Digital Commons Network^™

Genomic Based Environmental Health Assessment: Vieques, Puerto Rico, Valeria Hernandez Talavera

Graduate Doctoral Dissertations

From 1941 to 2003, the United States Navy and North Atlantic Treaty Organization (NATO) used Vieques, Puerto Rico, for military training, which led to long-term pollution from metals, organic chemicals, explosives, and per- and polyfluoroalkyl substances (PFAS). While earlier research found these contaminants in the environment and in living organisms, their combined effects on local ecosystems remain poorly understood.

This dissertation used a Genomic-Based Environmental Health Assessment (GEHA) framework to study the ecological risks from past military pollution in Vieques. The approach combined sediment toxicity tests, chemical analysis, gene expression studies, microbial community analysis, and community-based research. The four main …

Identifying Discrete Reappraisals And Examining The Properties Of Cognitive Reappraisal That Predict Emotional Outcomes, Jenny L. Wu

Graduate Doctoral Dissertations

Cognitive reappraisal is widely regarded as an adaptive emotion regulation strategy and a central strategy to promote cognitive change in psychological treatments. However, findings regarding its effectiveness have been inconsistent, potentially due to the tendency to conceptualize reappraisal as a uniform process. The present study sought to adopt a more fine-grained, process-oriented approach by examining variability in how reappraisal is implemented. Specifically, this study investigated (1) the overall effectiveness of cognitive reappraisal, (2) whether the perceived believability of reappraisals predicts emotional outcomes, and (3) whether different types of reappraisals are associated with differences in emotional outcomes. Participants completed a modified …

“School’S Not For Me. I Don't Belong In School.”: Students With Dis/Abilities’ Perspectives On Special Education During State Intervention, Leila E. Parks

Graduate Doctoral Dissertations

This qualitative study presents the lived experiences of 10 racialized teens with dis/abilities who received special education services in the Boston Public Schools during state intervention. As a youth participatory action research collective, the young people in the study’s Youth with Dis/Abilities Research Group explored issues of inclusion and exclusion, ableism, racism, and safety at school. The project was framed by dis/ability critical race studies, incorporating aspects of critical race theory and disability studies in education. Based on stories expressed through free-writes, poetry, drawings, interviews, and group conversations, the racialized teens with dis/abilities shared negative school experiences overall. Though most …

Innovating A Crustacean Embryo Toxicity (Cet) Assay For Screening Environmental Contaminants, Irina A. Polunina-Proulx

Graduate Doctoral Dissertations

Environmental pollutants can disrupt normal developmental processes, leading to neurobehavioral and developmental abnormalities. Toxicity tests are important for evaluating environmental contaminants; however, standard assays are often time- and cost-intensive and typically require large numbers of vertebrate animals. These limitations highlight the need to reduce reliance on vertebrate testing and to develop New Approach Methodologies that provide comparable results while improving efficiency and cost-effectiveness. This research utilizes a novel screening assay to evaluate developmental toxicity using Hyalella azteca. H. azteca is a freshwater amphipod widely used as a model organism for sediment toxicity in ecotoxicology, yet its embryos have been minimally …

Home, Neighborhood, And Community Environments And Social Isolation In Later Life: Joint Associations And Their Moderation By Life-Course Socioeconomic Mobility, Jeein Law

Graduate Doctoral Dissertations

Social isolation is a major public health concern among older adults, yet less is known about how multilevel residential environments shape isolation among those aging in place. Guided by the Socio-Ecological Model, Person–Environment Fit, and a life-course perspective, this dissertation examined whether micro-level home hazards, meso-level neighborhood social cohesion and physical disorder, and macro-level census-tract structural conditions were associated with social isolation. It also examined whether life-course socioeconomic mobility moderated the associations between home and neighborhood environments and social isolation.

This dissertation used two nationally representative longitudinal studies of U.S. older adults. Aims 1 and 2 used the National Health …

From Structure To Experiences: How Facility Capacity And Staffing Shape The Adoption And Impact Of Lgbt-Affirming Policies In Long-Term Care, Andrew Alberth

Graduate Doctoral Dissertations

Long-term care (LTC) settings – including nursing homes (NHs) and assisted living facilities (ALFs) – provide necessary care for individuals with extreme health and functioning limitations. Sexual and gender minority (LGBT) older adults report challenges receiving effective, person-centered care LTC. Some LGBT older adults may hide their sexual orientation and gender identity when entering LTC settings or delay seeking needed LTC fearing discrimination from staff and other residents. Furthermore, staff in LTC settings indicate little awareness of LGBT-residents and possess inadequate LGBT-cultural competency necessary for providing person-centered care. Therefore, LGBT-residents LTC experiences remain underexplored in the broader research. Adopting LGBT-affirming …

Solving For X: Centering Black Girls’ Experiences In Mathematics Education, Natasha A. Fortes

Graduate Doctoral Dissertations

Black girls can grow up, attend school, and move through their math classes without ever feeling seen as capable mathematical thinkers. Their teachers may not affirm their brilliance. Their voices may even go unheard. Math classes may not be a space where they can imagine themselves belonging. These experiences do not reflect ability. Instead, they reflect on the conditions in which they are expected to learn. This study centers the voices of Black girls and asks what they deserve from their mathematics education and instructors to develop a mathematics identity. The study is grounded in Black feminist traditions and draws …

Our Claims Matter: Latin American Migrants’ Nonviolent And Everyday Resistance Across Transnational Spaces, Pryanka Penafiel-Cevallos

Graduate Doctoral Dissertations

This dissertation examines how Latin American migrants engage in nonviolent resistance across transnational spaces in Ecuador, challenging dominant narratives that portray migrants primarily as passive actors or humanitarian subjects. Focusing mainly on Venezuelan, Colombian, and returned Ecuadorian migrants, the study places migrants’ political agency at the center of analysis. It asks how migrants resist, for what purposes, and under which conditions they mobilize nonviolent and everyday resistance practices to claim rights, dignity, and human security in a host country marked by both legal innovation and growing exclusion.

Drawing on civil resistance theory, everyday resistance approaches, and migration scholarship, the research …

Governing Climate Change For Sustainable Food Security In The Busoga Region Of Uganda, James Kintu

Graduate Doctoral Dissertations

Busoga, Uganda's most sugarcane-intensive sub-region, hosts seven mills and an expanding outgrower economy, yet remains among Uganda's most food-insecure areas, with over half of its households food-insecure. This study examined how governance of climate change and sugarcane expansion shapes capabilities for food access, land tenure, and decision-making among women, youth, and land-poor households in Jinja and Buyende.

The study developed an integrated CA-CEP-RFS framework, combining the Capability Approach, Comparative Environmental Politics, and the Resilient Food Systems framework, with Sen's Entitlement Framework bridging capabilities to production, trade, own-labor, and transfer entitlements. A qualitative case study drew on a documentary review, 27 …

I Must Be Well, To Do Well: Examining The Relationship Between Toxic Stem Environments, Trauma, Stem Support, And Academic Outcomes Among Diverse Graduate Women In Stem, Aisha Farra

Graduate Doctoral Dissertations

Women, particularly Women of Colour (WOC), remain underrepresented in STEM. In the last two decades, research has sought to better understand women’s experiences in STEM, highlighting challenges such as isolation, sexism, and racism, which negatively impact mental health and STEM persistence. While these mental health challenges have been documented, further work is needed to examine how these experiences are related to trauma symptoms and physical health outcomes, as well as the mechanisms through which they shape academic outcomes. This quantitative study investigated the relationships among toxic STEM experiences (i.e., gendered racism, sexism, and isolation), trauma symptoms and physical health concerns, …

Understanding Factors Influencing Multiple Tobacco Product Use Among Adolescents In Thailand: A Structural Equation Modeling Approach, Chaowalit Srisoem

Graduate Doctoral Dissertations

Tobacco use among Thai adolescents is shaped by personal, environmental, and product-related factors. However, the pathways linking these influences to actual behavior remain unclear. This study examined how personal, environmental, and product-related factors, along with intentions to use, relate to tobacco use among Thai adolescents. A cross-sectional secondary analysis was conducted using data from the 2022 Thailand Global Youth Tobacco Survey of 6,235 students aged 13–15 years. Survey weights methods were applied to produce nationally representative estimates. Confirmatory factor analysis and structural equation modeling assessed latent constructs, and multinomial logistic regression examined predictors of single, dual, and multiple product use. …

Multicomponent Reaction-Initiated Synthesis Of Polyheterocyclic Compounds, Ashutosh Nath

Graduate Doctoral Dissertations

Efficient synthesis of novel heterocycles with biological interest remains a challenge in modern organic chemistry. This dissertation presents the development of efficient synthetic strategies that combine multicomponent reactions (MCRs) with sequential reactions for rapid access a diverse array of polyheterocyclic compounds. The projects are: 1) Groebke-Blackburn-Bienaymé (GBB) reaction followed by N-acylation and Friedel-Crafts (FC) cyclization for the construction of imidazopyridine- and indole-fused azepinones involving an unusual ring-expansion process. 2) Modified GBB condensation products for intramolecular Diels-Alder (IMDA) cycloaddition and dehydrative re-aromatization to access imidazopyridine-fused isoquinolinones. 3) Integration of the Ugi-three component reaction (Ugi-3CR) and Pictet-Spengler (PS) reaction followed by …

Dynamics Of Swimming Microorganisms At Structured Liquid Crystal Interfaces, Vajra Sabhapathy Badha

Graduate Doctoral Dissertations

Active matter systems are self-driven units that consume energy to generate motion and mechanical stresses, producing non-equilibrium states of broad physical significance. Examples include synthetic microswimmers and migrating cells. Motile bacteria are a widely studied biological example because their self-propelled motion, hydrodynamic interactions, and collective organization are strongly coupled to local environmental conditions. Their swimming is sensitive to interfacial viscoelasticity, ordering, confinement, and hydrodynamic boundary effects, making them useful for investigating how interfaces regulate active biological motion. Because bacterial accumulation and attachment at interfaces are central to colonization and biofilm formation, these interactions are relevant to both active matter physics …

The Effect Of State Policy On Individuals With Mental Illness In Nursing Homes: A Multilevel Analysis, Adrita Barooah

Graduate Doctoral Dissertations

ABSTRACT

THE EFFECT OF STATE POLICY ON INDIVIDUALS WITH MENTAL ILLNESS IN NURSING HOMES: A MULTILEVEL ANALYSIS

August 2026

Adrita Barooah, B.Sc., University of Delhi, India

M.S., University of Massachusetts Boston

Ph.D., University of Massachusetts Boston

Directed by Professor Pamela Nadash

The proportion of individuals living with a mental illness in U.S. nursing homes has grown substantially over the past few decades (Fashaw et al., 2020), raising serious concerns about care quality, resource adequacy, and costs to both nursing homes and government payers. The lack of adequate resources and knowledge has resulted in sub-par mental health care (O'Connor et al., …

Nihilistic Violence Aesthetics In Public Online Communication, Heath Nicholas Landress

Journal of Social, Behavioral, and Health Sciences

Public online communication has increasingly included violence-related content that is meme-based, ironic, visually stylized, multimodal, and only partially ideological. This comprehensive literature review synthesized research on online extremism, extremist memes, toxic multimodal content, dehumanizing digital communication, nihilistic violent extremism, warning behaviors, platform affordances, and youth-facing online environments. The purpose was to clarify what the literature had established; identify where the scholarship remained fragmented; and map research domains relevant to social, behavioral, public safety, and human services scholarship. The review used a structured, comprehensive literature review strategy supported by integrative synthesis procedures. The final corpus contained 34 scholarly sources, including 32 …

Plaza Off The Park, Hdfc V. Mcgowan

All Decisions

Court dismissed holdover against proprietary lessee in HDFC because petition failed to accurately describe the regulatory status of the unit and tenancy as required by RPAPL § 741(4). Court held that respondent's ability to independently discover the correct regulatory status does not obviate the landlord's burden to describe the premises accurately in the petition from the start.

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Gamclust: Identification Of Regulated Metabolic Modules In Bulk, Single Cell And Spatial Gene Expression Data, Anastasiia Gainullina, Evgeniia Chikina, Maxim N Artyomov, Alexey Sergushichev

2020-Current year OA Pubs

MOTIVATION: Metabolism operates as a highly interconnected biochemical network, and its regulation emerges from coordinated changes across many reactions and metabolites. The integration of gene expression profiling data with organism-scale metabolic networks has proven to be a valuable tool for understanding cellular metabolic regulation. However, the increasing complexity of profiling technologies and experimental designs requires the development of specialized tools.

RESULTS: Here, we present GAMclust, an R package implementing and extending the previously published GAM-clustering pipeline for identifying transcriptionally regulated metabolic modules in complex gene expression datasets. GAMclust supports bulk, single-cell, and spatial gene expression profiling. It includes built-in KEGG …

A Novel Approach For Evaluating And Comparing Multiple Antipsychotic Polypharmacy In Adults Across Specialist Intellectual Disability Services In England And Wales: A Retrospective Feasibility Cohort Study, Samuel J. Tromans, Helen Neilens, Crispin Musicha, Victoria Allgar, Emily Stanyard, Richard Laugharne, Paula Mcgowan, Angela Hassiotis, Sarah Lennard, Lance V. Watkins, Bhathika Perera, Kiran Purandare, Ashok Roy, Indermeet Sawhney, Sujeet Jaydeokar, Ryan Ashford, Chris Rollinson, Hanna Abraham, Nusra Khodabux, Ogheneochuko Akusu, Samuel Paisley, Georgios Mousailidis, Meera Naran, Rohit Shankar

Peninsula Medical School

Background:In England and Wales, significant numbers of people with intellectual disability (PwID) are prescribed antipsychotics for a range of licensed and non-licensed indications, particularly behaviours that challenge. There is no system to compare antipsychotic prescribing practices across specialist adult intellectual disability (ID) services.Aim:This study aimed to determine whether converting antipsychotics and their doses to equivalent chlorpromazine units enables comparison of licensed (psychosis, etc.) and non-licensed (behaviours that challenge) prescribing between different services.Method:A feasibility retrospective cohort study using convenience sampling captured anonymized data of PwID on ⩾2 antipsychotics across eight specialist England and Wales adult ID services. The doses prescribed across …

Lanthorn, Vol. 61, No. 02, August 31, 2026, Grand Valley State University

Volume 61, August 10, 2026 – current

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Principals’ Experiences With Implementation Practices For School Board Policies In An Urban School District, Andrea J. Richardson

Walden Dissertations and Doctoral Studies

Effective policy implementation is crucial for improving educational outcomes and ensuring equitable learning environments. While existing literature has shown that policy implementation is influenced by factors such as leadership capacity, stakeholder engagement, communication, resource availability, organization context, and accountability, there is little known about how K-12 urban principals narrate, interpret, and make meaning of their experiences to implementing board-mandated policies. This study addressed this gap by exploring how principals in an urban school district in Ohio navigated the complexities of implementing school board policies amid resource limitations, stakeholder resistance, and accountability pressures. The purpose of this qualitative narrative inquiry study …

Searching The Druggable Genome Using Large Language Models, Lars Schimmelpfennig, Matthew Cannon, Quentin Cody, Joshua Mcmichael, Adam C Coffman, Susanna Kiwala, Kilannin Krysiak, Alex H Wagner, Malachi Griffith, Obi L Griffith

2020-Current year OA Pubs

SUMMARY: The druggable genome encompasses the genes that are known or predicted to interact with drugs. The Drug-Gene Interaction Database (DGIdb) provides an integrated resource for discovering and contextualizing these interactions, supporting a broad range of research and clinical applications. DGIdb is currently accessed through structured web interfaces and API calls, requiring users to translate natural-language questions into database-specific query patterns. To allow for the use of DGIdb through natural language, we developed the DGIdb Model Context Protocol (MCP) server, which allows large language models (LLMs) access to up-to-date information through the DGIdb API. We demonstrate that the MCP server …

Re: 2nd Quarter 2026 – Interim Site-Wide Surface Water Monitoring Data Report Silver Bow Creek Butte Area Npl Site, Butte Priority Soils Operable Unit Consent Decree-Civil Action No. Cv 89-039-Bu-She, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites: Ur-35 Construction Completion Report (Ccr), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

The purpose of this Butte Priority Soils Operable Unit (BPSOU) Unreclaimed (UR) Sites Construction Completion Report (CCR) is to describe the tasks completed as described in the Final BPSOU UR Sites: UR-35 Remedial Action Work Plan (RAWP) (referred to herein as RAWP; Atlantic Richfield Company, 2025) (Appendix A). This CCR was prepared to outline Remedial Action (RA) tasks performed at the UR source area, UR-35, within the BPSOU (referred to herein as UR-35 Site or Site) as part of the Further Remedial Elements Scope of Work described in the BPSOU Consent Decree (EPA, 2020). All work was completed according to …

Law Enforcement In Providing Protection For Revenge Porn Victims On Social Media, Augustha Kwanzaa Rich Samuel Simbolon, Muhammad Rivan Subarna

Jurnal Vokasi Indonesia

Revenge porn, which is the distribution of pornographic material without the victim's consent, is a serious and growing problem online. This practice is usually carried out by ex-partners in revenge, by distributing intimate images or videos of the victim to the internet. This research aims to identify the impact of revenge porn on victims, as well as assess the effectiveness of existing legal protection. The method used is a qualitative approach through literature study. The data collected includes revenge porn cases that occurred in Indonesia, as well as a review of regulations governing the protection of privacy and victims' rights. …

Optimal Quantitative Controller Design For Twin Rotor Mimo System, Mustafa Khreabet, Hazem Ali

Engineering and Technology Journal

In this paper, the control approach is used for achieving the desired performance and stability of the twin-rotor MIMO system. This system is considered one of the complex multiple inputs of multiple-output systems. The complexity because of the high nonlinearity, significant cross-coupling and parameter uncertainty makes the control of such systems is a very challenging task. The dynamic of the Twin Rotor MIMO System (TRMS) is the same as that in helicopters in many aspects. The Quantitative Feedback Theory (QFT) controller is added to the control to enhance the control algorithm and to satisfy a more desirable performance. QFT is …

Experimental And Numerical Investigation Into Residual Stress During Turning Operation For Stainless Steel Aisi 316, Safa Lafta, Maan Tawfiq

Engineering and Technology Journal

RS (residual stresses) represent the main role in the performance of structures and machined parts. The main objective of this paper is to investigate the effect of feed rate with constant cutting speed and depth of cut on residual stresses in orthogonal cutting, using Tungsten carbide cutting tools when machining AISI 316 in turning operation. AISI 316 stainless steel was selected in experiments since it is used in many important industries such as chemical, petrochemical industries, power generation, electrical engineering, food and beverage industry. Four feed rates were selected (0.228, 0.16, 0.08 and 0.065) mm/rev when cutting speed is constant …

Extended Meshfree Approach For Crack Statistical Analysis Of Anisotropic Functionally Graded Brazilian Disc Subjected To Traction Load, Hassanein Khalaf, Haider Mehbes, Ameen Nassar

Engineering and Technology Journal

An extended meshless method that relying upon Galerkin formulation is applied on the crack analysis of orthotropic functionally graded Brazilian disc. Weak form is involved to solve the governing equation in the numerical method. In addition, enrichment terms and sub-triangle techniques are applied to improve the accuracy of relevant results. This paper depicts the influence of variation in the crack stretch and non-homogeneity parameters on the values of stress intensity factors using a developed MATLAB program. In the isotropic case, it is clear that when the length of crack increases, SIF increases. Graduation in has more effect in increasing the …

Investigation The Effect Of Negative Polarity Of Surface Roughness And Metal Removal Rate During Edm Process, Shahd Taqi, Saad Shather

Engineering and Technology Journal

The Electro discharge machine that named (EDM) is used to remove the metal from the workpiece by spark erosion. The work of this machining depends on the multiple variables. One of the most influential variants of this machine is the polarity, the material of the electrode, the current and the time pulses. Essentially the polarity of the tool (electrode) positive and the work piece is negative, this polarity can be reversed in this paper was reversed the polarity that was made the tool (electrode) negative and the work piece was positive. The aim of this paper was focused on the …

Prediction Of Surface Roughness Of Mild Steel Alloy In Cnc Milling Process Using Ann And Ga Technique, Hind Abdulridha

Engineering and Technology Journal

In this paper, Analysis Of Variance (ANOVA), Artificial Neural Network (ANN), and Genetic Algorithm (GA) have been studied to predict the effect of milling parameters on the Surface Roughness (Ra) during machining of mild steel alloy. The milling experiments carried out based on the Taguchi design of experiments method using (L16) orthogonal array with 3 factors and 4 levels. The influence of three independent variables such as spindle speed (910, 930, 960, and 1000 rpm), feed rate (93, 95, 98, and 102 mm/min), and Tool Diameter (8, 10, 12, and 14 mm) on the Surface Roughness (Ra) were tested and …