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Shadowless In A World Of Shadows: Diminishing The Refraction Of Light Via Nanoconfinement, Vuk Uskoković

Administration and Staff Articles and Research

This paper presents a physicochemical study that merges science and art in the context of exploring the refractive index of water under nanoconfinement. Using a simple and economical experimental approach, it is shown that confinement within the micropores of a zeolitic structure, characterized using electron microscopy and X-ray diffraction, paradoxically reduces the refractive index of water, bringing confined water droplets closer to a shadowless state. Counterintuitively, water under confinement, as indicated by vibrational spectroscopic analyses performed in the transmittance mode in the IR range and reflectance mode in the near-IR range, exhibits greater structural freedom than in its bulk or …

Using Early And Periodic Screening, Diagnostic, And Treatment (Epsdt) To Improve Access To Obesity Pharmacotherapy: A Practical Guide For Clinicians Caring For Youth With Obesity Across United States Medicaid Programs:, Jaime M. Moore, Valerie M. O'Hara, Cassie Totman, Brooke Sweeney, Sarah Hampl, Alaina P. Vidmar

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Coverage of obesity pharmacotherapy for youth varies substantially across state Medicaid programs. This variability limits access to evidence-based treatment for pediatric obesity. The Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) benefit is a federally mandated Medicaid provision requiring coverage of medically necessary services for individuals under age 21, even when such services are not included in standard state Medicaid benefits. Despite its broad scope, EPSDT remains underutilized due to limited awareness and operational complexity.

METHODS: We developed a clinician-facing, practice-oriented framework to operationalize EPSDT for pediatric obesity treatment. This approach integrates (1) review of federal EPSDT policy and …

20260901: Alumni Association, 1932-2024, Alumni Association

Guides to University Archives

These items include materials from the Alumni Association at Marshall University from 1932-2024. Items were received in 2026 and include notable materials from or about the Alumni Office and other campus events including Herald-Advertiser issues of early campus, the Sesquicentennial Souvenir Section from the Herald-Dispatch, issues of The Parthenon, Marshall Magazine, the Marshall High School Yearbook from the 1960s "The Brigadier", a songbook from Sigma Alpha Epsilon, and other materials from Sigma Alpha Epsilon from the 1960s and 1980s. This is not an exhaustive list. Please download the finding aid for a full list of contents.

Single Immunoglobulin Interleukin1-Related Receptor-Twist1 Axis Regulates Barrier Function In Neonatal Intestine., Aparna Venkatraman, Wei Yu, Heather Menden, Sherry M. Mabry, Joshua Wheatley, Shahid Umar, Susana Chavez-Bueno, Venkatesh Sampath

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND & AIMS: The genetic basis of impaired intestinal barrier function in preterm infants is poorly understood. Variants in single immunoglobulin interleukin1-related receptor, a negative regulator of Toll-like receptor signaling, have been identified in preterm infants with necrotizing enterocolitis. We hypothesized that single immunoglobulin interleukin1-related receptor variants associated with necrotizing enterocolitis impair gut barrier function to pathobionts. The aim of this study was to determine how single immunoglobulin interleukin1-related receptor genetic variants disrupt neonatal intestinal barrier integrity and promote susceptibility to Gram-negative bacteria implicated in sepsis and necrotizing enterocolitis pathogenesis.

METHODS: Transgenic mice and preterm infant-derived enteroids expressing SIGIRR variants …

Non-Vigorous Physical Activity Associated With Reduced Hospitalization Risk With Or Without Diabetes Or Peripheral Artery Disease: Study Of Latinos., Sarah K. Alver, Carmen C. Cuthbertson, Kelly R. Evenson, Jennifer A. Schrack, Daniela Sotres-Alvarez, Natasha Z. Anita, Yasmin Mossavar-Rahmani, Linda C. Gallo, Jordan A. Carlson, Matthew Allison, Martha L. Daviglus, Olga Garcia-Bedoya, Christina Cordero, Xiaonan Xue, Jianwen Cai, Kunihiro Matsushita, Robert C. Kaplan

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: This study assessed whether greater physical activity (PA) and lesser sedentary behavior (SB) reduce hospitalization risk equally among those with and without prediabetes, diabetes, or peripheral artery disease (PAD).

METHODS: We studied PA, SB and hospitalizations in 12,734 adults from the Hispanic Community Health Study/Study of Latinos, who were 52.2% female with mean (standard deviation) age 41.1 (14.9) yr at baseline. Participants reported 10,025 nonpregnancy-related hospitalizations (excluding emergency room only) over 13 yr. We modeled the association between accelerometer-measured activity (SB; light intensity physical activity [LPA]; moderate physical activity [MPA]; vigorous physical activity [VPA]) and hospitalization, using Andersen-Gill proportional …

Prediction Of Decline In Ovarian Function In Turner Syndrome., Roopa Kanakatti Shankar, Tazim Dowlut-Mcelroy

Manuscripts, Articles, Book Chapters and Other Papers

Comment on

• The role of hormonal markers in predicting reproductive lifespan in girls with Turner syndrome-a retrospective study. van der Coelen S, Sas T, Richter-Unruh A, Braat D, Fleischer K, Nadesapillai S, IntHout J, van der Velden J.J Endocr Soc. 2026 Jun 5;10(7):bvag122. doi: 10.1210/jendso/bvag122. eCollection 2026 Jul.PMID: 42272567 Free PMC article.

Inosine-Triphosphate-Pyrophosphatase Activity As A Potential Predictor Of Methotrexate Remission In Juvenile Idiopathic Arthritis., Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Methotrexate (MTX) is the first-line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro.

METHODS: ITPA enzymatic activity was measured by high-performance liquid chromatography with ultraviolet detection in erythrocyte lysates from patients with JIA (enrolled in Trieste, Italy; Florence, Italy; and Kansas City, Missouri) receiving weekly MTX (10-15 mg/m²) for at least 12 months. Remission was evaluated by Wallace et al criteria. ITPA rs1127354, which …

Association Between Estimated Time With Low Glomerular Filtration Rate And Access To Transplant Among Youth With Advanced Chronic Kidney Disease., Elaine Ku, Timothy Copeland, Charles E. Mcculloch, Jonathan D. Savant, Bradley A. Warady, Susan L. Furth, Sarah Kizilbash, Daniel I. Feig, Roshan P. George, Joseph T. Flynn, Judith Jerry-Fluker, Matthew B. Matheson, Sandra Amaral, Ckid Investigators

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Slower chronic kidney disease (CKD) progression allows more time for transplant preparation. Whether differences in CKD progression by race/ethnicity associate with preemptive or living donor transplantation in youth has not been well studied.

METHODS: We examined the association between time spent with low eGFR (between 10-30 mL/min/1.73 m²) and odds of preemptive or living donor transplantation among youth with CKD. eGFR was estimated using the bedside Schwartz (if < 18 years) and CKD-EPI 2021 equations (if ≥ 18 years) and the CKiD U25 equation in sensitivity analysis. Time spent with low eGFR was compared by race/ethnicity.

RESULTS: Among 333 youth with CKD (median age 11 years [IQR 7,14]), median time spent with low eGFR was 28.8 months. 77% were preemptively waitlisted, and 45% received preemptive …

The Rise And Fall Of Lateral Electrical Surface Stimulation (Less) Through The Lens Of Srs Archives., Ali Rezazadeh Shirazi, Jay I. Kumar, Katie Dold, George H. Thompson, Andrew G. King, Richard M. Schwend, John P. Lubicky, Jay Shapiro, Behrooz A. Akbarnia, History Committee Of The Scoliosis Research Society

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Lateral electrical surface stimulation (LESS), commercially known as the ScoliTron™, emerged in the late 1970s as a noninvasive alternative to bracing for adolescent idiopathic scoliosis. Early clinical reports generated considerable enthusiasm and adoption, but the technique was ultimately abandoned. This study examined the rise and fall of LESS through a combined analysis of the Scoliosis Research Society (SRS) archives and published literature, with the goal of understanding factors that influence the adoption, evaluation, and abandonment of innovation in scoliosis care.

METHODS: A structured historical review was conducted using archival materials from the Scoliosis Research Society (SRS), including meeting abstracts, …

Posaconazole Target Attainment In Critically Ill Children: A 15-Year Single-Center Retrospective Analysis., Kathryn Pavia, Addison M. Pritchett Ms, Jennifer Goldman

Manuscripts, Articles, Book Chapters and Other Papers

Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter-individual variability in dose-exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU) patients related to changes in physiology during critical illness. The rates of subtherapeutic posaconazole exposure among critically ill children in ICU's are unknown. This single-center retrospective analysis at a large freestanding children's hospital used TDM results from 2010 to 2025 obtained while patients were undergoing care in a pediatric ICU. Therapeutic targets were ≥ 1.0 mg/L …

Maternal Violent Injury And Child Exposure To Violence-A Call For Trauma-Informed And Structural Responses., Gunjan Tiyyagura, M Katherine Henry, Kimberly Randell

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Characteristics Of Individuals With Cerebral Palsy Across The Us., Bhooma R. Aravamuthan, Amy F. Bailes, Micah Baird, Kristie Bjornson, Ira Bowen, Angeline Bowman, Elizabeth R. Boyer, Rose N. Gelineau-Morel, Laurie Glader, Paul H. Gross, Stacey Hall, Edward A. Hurvitz, Michael Kruer, Thomas Larrew, Neena I. Marupudi, Patrick G. Mcphee, Stephen A. Nichols, Garey Noritz, Joyce Oleszek, Justin Ramsey, Jeffrey S. Raskin, Heather Riordan, Brandon G. Rocque, Manish N. Shah, Benjamin J. Shore, M Wade Shrader, David Spence, Charles B. Stevenson, Richard Stevenson, Sruthi P. Thomas, Joyce P. Trost, Stephen R. Wisniewski, Cerebral Palsy Research Network

Manuscripts, Articles, Book Chapters and Other Papers

This cross-sectional study examines how demographics and characteristics of individuals with cerebral palsy across the US associate with Gross Motor Function Classification System level and genetic etiology.

Outcomes For Congenitally Corrected Transposition Of Great Arteries Using Various Surgical Techniques: A Systematic Review And Network Meta-Analysis., S U Hasan, Sur Usmani, S H Ahmed, A Pervez, M A Kamalia, A D Shah, Mujeeb Zubair

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Congenitally corrected transposition of the great arteries (ccTGA) is a rare disorder. Here, we evaluated the effectiveness of physiological, anatomical and Fontan repair techniques for ccTGA.

METHODS: A systematic database search in PubMed, Embase and Cochrane Central Register of Controlled Trials was conducted from inception to 5 June 2023. Random-effects network meta-analysis was performed, comparing mortality, postoperative arrhythmias, reintervention after definitive surgery and transplant-free survival in patients undergoing physiological, anatomical and Fontan repair.

FINDINGS: A total of 1,209 patients were included from nine studies. Fontan repair was associated with a higher rate of transplant-free survival (absolute risk [AR] 0.999 …

Patient-Specific Computational Fluid Dynamics Modeling Of Airway Collapse In Infants With Robin Sequence., Gautam Jalori, Michael Barbour, Michael Bindschadler, Kelly Evans, John P. Dahl, Alberto Aliseda

Manuscripts, Articles, Book Chapters and Other Papers

Robin Sequence (RS) is a congenital condition in which patients experience dynamic, periodic obstruction or collapse of the upper airway due to an underdeveloped jaw and a posteriorly displaced tongue. Current clinical techniques for evaluating airway obstruction do not provide quantifiable data and fail to account for the dynamic nature of obstruction or collapse. There is no standardized criterion to characterize obstruction or collapse severity. This study presents the first method that extracts airway motion from 4-dimensional computed tomography and performs a patient-specific, moving-mesh computational fluid dynamics (CFD) analysis of RS patients with complete airway collapse or obstruction. To quantify …

Hla-Dr Expression At Diagnosis Is Not Predictive Of Relapse Risk Post Allogeneic Hematopoietic Stem Cell Transplantation For Pediatric Acute Myeloid Leukemia: A Report From The Children's Oncology Group., Vasant Chinnabhandar, Michael R. Verneris, Kirk R. Schultz, Alan S. Gamis, Richard Aplenc, Chad A. Hudson, Todd A. Alonzo, Robert B. Gerbing, John T. Horan, Joseph H. Chewning

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Udm Dean's Report - A Look At The Student Of Today As We Prepare Them For Tomorrow, Mert N. Aksu Dds, Jd, Mhsa, Cert. Dph

The Journal of the Michigan Dental Association

UDM Dental School Dean Mert N. Aksu discusses the profiles, expectations, and challenges of modern dental students, highlighting their collaborative nature, tech-savviness, and focus on wellness and work-life balance. The report outlines UDM's clinical curriculum enhancements, including systems-based biomedical integration, and extensive clinical practice labs. Aksu addresses the substantial 58% inflation-adjusted rise in educational debt since 2008 and updates on community service rotations (Corktown Clinic, Titans for Teeth), the implementation of the new Vermont Track for rural care, the adoption of AI radiographic analysis, and comprehensive student mental health support programs.

Um Dean's Report - Meeting The Challenge Of Educating Dentists In A Constantly Evolving Profession, Jacques E. Nör

The Journal of the Michigan Dental Association

University of Michigan School of Dentistry Dean Jacques Nör highlights the school's historical legacy during its 150th anniversary and details recent academic, clinical, and research progress. Key developments include the establishment of the state-of-the-art Digital Dentistry Center for in-house digital workflows, a pediatric certificate program in Social Epidemiology funded by a $2.1 million federal grant, the transition to Epic electronic health records (integrated with MyChart), and the community-based collaborative care rotation program in Marquette. The report also highlights national faculty leadership roles and $24.1 million in research funding.

Is Prenatal Contraceptive Counseling Enough? Intimate Partner Violence Timing And Postpartum Contraception In Hispanic Women, Lucas E. Espinoza, Luis Enrique Espinoza, Paris G. Rangel, Jennifer L. Talleff, Amiee Griffis

Criminal Justice Faculty Publications

Purpose: Intimate partner violence (IPV) is a major public health concern that can impact women’s reproductive decisions, but how IPV timing and prenatal contraceptive counseling are associated with postpartum contraceptive use in Hispanic women is poorly understood. This study examines the association between IPV timing, prenatal contraceptive counseling, and postpartum contraceptive use among Hispanic women.

Methods: Data were drawn from the 2019–2020 Pregnancy Risk Assessment Monitoring System and included 11,721 Hispanic women who had recently given birth. IPV was classified based on timing as none, preconception, prenatal, or both. Multivariable logistic regression models were estimated with analyses moderated and stratified …

La Citación En Educación: Funciones Retóricas En Textos Académicos Escritos Por Expertos Y Estudiantes Universitarios, David Sanchez-Jimenez, Juan Antonio Núñez Cortés, Enrique Alonso Sainz

Publications and Research

The present study aims to investigate the differences in citation usage and frequency among university students and expert writers in the field of Education. The analyzed corpus comprises 50 papers written in this discipline and is divided into two sub-corpora: one consisting of 25 TFGs and the other one formed by 25 articles published in specialized journals. To examine this phenomenon, a qualitative and quantitative methodology was employed, performing a textual analysis of the rhetorical functions of citations. This analysis is based in the typology proposed by Petrić in her 2007 article, slightly modified for the purpose of the present …

Diversity And Species Richness Of Lepidopteran Stemborers And Their Host Plants Across Major Vegetation Mosaics Of East Africa, Elie Ntirenganya, Muluken Goftishu, Yoseph Assefa, Bonoukpoè Mawuko Sokame, Simon Boniface Boni, Janvier Uwayezu, Hategekimana Athanase, Venuste Nsengimana

All Peer-Reviewed Publications

The study was carried out in the major ecological vegetation mosaics of Rwanda, including Afro-alpine mountain mosaics within the Guineo–Congolese region in the north; Akagera sub-humid savanna mosaics in the east; montane forest mosaics in the south; and modified urban wetland and riparian mosaics of Kigali City, within the Sudanian–Guinea–Congo transition zone. At each selected locality, purposive sampling in (i) edges of the cultivated field and adjacent uncultivated lands, (ii) open patches along the forest access roads and pathways, (iii) riparian zones along urban areas, rivers, and streams, (iv) edge of lakes, and (v) swamp ecosystems was conducted to detect …

Mitochondrial Phylogeography And Insecticide Resistance Of Aedes Aegypti In Kenya, Brenda Musimbi, Sandy Hickson, Trizah K. Milugo, Eleanor Robinson-Rice, Josephine Osalla, Gilbert Rotich, Frank Jiggins, David P. Tchouassi

All Peer-Reviewed Publications

Aedes aegypti is the primary vector of arboviruses such as dengue, yellow fever, Zika, and chikungunya. Here, we investigate the mitochondrial DNA (mtDNA) structure and insecticide resistance of Ae. aegypti populations across Kenya. Using 175 newly sequenced Kenyan COI mtDNA fragments, along with global reference sequences, we assess maternal ancestry and phylogeographic structure. Genetic structure across Kenya was not well explained by isolation-by-distance alone, with several populations deviating from this pattern. Nairobi and Mombasa, separated by >400 km, showed greater maternal genetic similarity than expected under isolation-by-distance, a pattern that may reflect gene flow along transportation corridors. Conversely, Ukunda, around …

Quantile Normalisation Enables Interpretable Spatial Prioritisation Of Persistence-Related Mechanistic Suitability Under Uncertainty For Tomato Red Spider Mite (Tetranychus Evansi) In Africa, Komi Mensah Agboka, Luca Rossini, Quinto Juma Meltus, Bonoukpoè Mawuko Sokame, Abdulmutallab G.A. Azrag, Thomas Dubois, Elfatih M. Abdel-Rahman

All Peer-Reviewed Publications

Mechanistic trait models are increasingly considered to estimate persistence-related suitability for invasive species, although translating reproduction metrics into operational indicators for spatial decision-making remains challenging. Branching-process transformations are widely applied to convert mechanistic reproduction numbers into probabilities of establishment; however, such transformations may compress spatial gradients when persistence is broadly feasible. Using tomato red spider mite (Tetranychus evansi) as a case study across Africa, this study developed an uncertainty-aware, physiologically-based model and generated spatially explicit estimates of expected reproduction (R0). We compared three representations: raw mechanistic suitability, branching-process persistence probability, and quantile-normalised suitability. Although all representations preserved rank ordering, branching …

Collecting Holistic Evidence On Agroecology Performance To Accelerate Sustainable Food System Transitions, Sarah K. Jones, Andrea Cecilia Sánchez, Chris Dickens, Matthias S. Geck, Chaturangi Wickramaratne, Veronique Alary, Peter Bolo, Dennis Junior Choruma, Somphasith Douangsavanh, Modou Gueye Fall, Gatien Falconnier, Shweta Gupta, Chris Kettle, Smitha Krishnan, Sylvia Nyawira, Guillermo Orjuela-Ramirez, Boko Michel Orounladji, Piedad Pareja, Telma Sibanda, Christine Lamanna

All Peer-Reviewed Publications

A growing body of research shows the potential of agroecology for enabling a shift to planet-friendly and socially just agrifood systems through context-specific transition pathways. We conduct a scoping review to identify and evaluate the potential of 42 existing agroecology adherence and/or agricultural performance assessment tools to generate credible, legitimate, salient and transferable evidence to inform these transitions. Results show that while multiple relevant tools exist, each of them can be strengthened in at least one area. While most tools are transferable (low time and resource requirements) and have legitimacy (open access with transparent methods), tools have variable saliency (holistic …

Machine Learning-Enabled Chemical Ecology For Integrated Pest Management: From Volatiles To Field Applications, Steve B.S. Baleba, Victor O. Omondi, Pascal Aigbedion-Atalor, Emmanuel Peter, Souleymane Diallo, Komi Mensah Agboka

All Peer-Reviewed Publications

Machine learning is transforming chemical ecology by accelerating the discovery and deployment of semiochemical-based tools for precision pest management. These advances are particularly important in the face of climate change, pesticide resistance, and the growing need for sustainable agricultural intensification. This review synthesizes how machine learning can be applied across the semiochemical discovery and implementation pipeline, from chemical signal detection to field deployment and decision support for integrated pest management. We review major machine learning approaches and demonstrate how they extract biologically relevant information from high-dimensional chemical, electrophysiological, behavioral, sensor, and field datasets. These methods accelerate semiochemical discovery, prioritize candidate …

Social Prescribing For People In Vulnerable Situations In Europe: Protocol For A Process Evaluation Of An Rct In Eight Countries, Kerryn Husk, Elizabeth Gilmour, Stephanie Tierney, Debra Westlake, Anuschka Arni, Hendrik Napierala, Farhad Rezvani, Marius Dierks, Wolfram J. Herrmann

Peninsula Medical School

Objective Social prescribing is a pathway that connects individuals to non-clinical services. It supports and addresses social needs, such as those related to loneliness, housing instability and mental health. Social Prescribing Europe (SP-EU), a European Union funded project, seeks to co-create an adaptation of the social prescribing pathway based on the needs of the following target groups: LGBTIQ+ people, refugees and first-generation immigrants, older people living alone. This adapted social prescribing pathway will be tested in a pragmatic randomised controlled trial (RCT) in ten hubs, covering eight countries, across Europe. The aim of this process evaluation is to explore the …

Reply, Jacqueline L. Chen, Amanda J. Lu, Rohan Verma, Li Wang, Douglas D. Koch, Allison J. Chen

Department of Medicine Faculty Papers

No abstract provided.

From Suitability To Invasion Risk: Integrating Correlative And Mechanistic Models For Predicting The Potential Distribution Of The Red Palm Weevil, Abdelmutalab G.A. Azrag, Komi Mensah Agboka, Elfatih M. Abdel-Rahman, Rehemah Gwokyalya, Seid A. Kemal, Hamadttu A.F. El-Shafie, Mohamed A. Bob, Samira A. Mohamed, Sunday Ekesi, Abdou Tenkouano

All Peer-Reviewed Publications

The red Palm Weevil (RPW) Rhynchophorus ferrugineus is the most devastating pest of palm trees and is responsible for significant economic and biodiversity losses worldwide. The larvae bore deep into the trunk or crown for feeding, resulting in extensive tunneling and mortality of the trees. In this study, we developed a hybrid modeling framework for RPW that integrates ecological niche modeling (ENMs) with a temperature-driven risk index (RI). The ENM was developed from the RPW occurrence data, while the RI was driven from temperature-dependent life history traits of RPW. The two approaches were combined through a weighted additive method to …

Measuring Quality Of Life In Advanced Chronic Liver Disease With Fact-Hep: Findings From The Pal Liver Trial, Manisha Verma, Binu John, Don Rockey, Sid Barritt, Victor Navarro, Linda Shaw, Andrzej Kosinski, Elliot Tapper, Archita Desai

Einstein Health Papers

BACKGROUND: Patient-reported outcome measures (PROMs) are increasingly incorporated into hepatology research, yet few have been rigorously evaluated, particularly among patients with decompensated cirrhosis. The Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) captures multidimensional liver disease-specific burden, while the disease-agnostic PROMIS-29 assesses physical and mental health broadly. We evaluated the performance of FACT-Hep and its relationship to PROMIS-29 among participants with cirrhosis or hepatocellular carcinoma (HCC) enrolled in a prospective multicenter clinical trial.

METHODS: Baseline data were analyzed from 935 participants enrolled in the PAL LIVER trial. This study enrolled patients with Child-Turcotte-Pugh (CTP) B/C cirrhosis and/or with HCC. Health-related quality of …

Remote Sensing Integrated Modeling Of Fall Armyworm Parasitoid Interactions In Africa Using Fractional Differential Equations, Marian Adan, Steeven Belvinos Affognon, Henri E.Z. Tonnang, Klaus Greve, Christian Borgemeister, Georg Goergen

All Peer-Reviewed Publications

The invasion of fall armyworm (Spodoptera frugiperda; FAW) into Africa poses a major threat to agricultural systems, particularly maize production, necessitating effective biological control strategies. This study presents an ecological modelling framework that integrates temperature data with fractional differential equations (FDEs) to investigate interactions between FAW and its parasitoid natural enemies. By incorporating temperature-driven effects on life-history traits and ecological memory dynamics, the model captures key features of host–parasitoid interactions under variable environmental conditions. Equilibrium states corresponding to FAW extinction, parasitoid extinction, and coexistence were analytically derived, and sensitivity analysis of the FAW reproduction number highlighted its central role in …

Noncoding Rna Transcripts Based Molecular Phenotyping Of Masld And Mash Patients, Frida M. Delgadillo, Karla Perez, Barbara Yang, Subramanian Dhandayuthapani, Murali Yallapu, Subhash C. Chauhan, Enrique I. Ramos, Shrikanth S. Gadad

School of Medicine Publications

Background and aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive hepatic metabolic disorder characterized by excessive fat accumulation in hepatocytes. MASLD can advance to metabolic dysfunction-associated steatohepatitis (MASH). These conditions often lead to hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC) if not timely diagnosed and managed; thus, molecular phenotyping of MASLD and MASH conditions is highly desirable. The analyses were performed to identify distinct, differentially expressed genes, particularly noncoding ones, in MASLD and MASH patient samples, thereby expanding diagnostic and therapeutic options.

Methods: We extracted the data from a recent transcriptomic study by Govaere et al. on MASLD …