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Articles 115651 - 115677 of 115677
Full-Text Articles in Entire DC Network
Obesity Education For Occupational Therapy Students: A Missing Piece?, Laura Stocksborough, Shirley Masterson-Ng
Obesity Education For Occupational Therapy Students: A Missing Piece?, Laura Stocksborough, Shirley Masterson-Ng
Journal of Occupational Therapy Education
People with obesity experience discrimination and stigma at the hands of healthcare workers who often fail to address associated complexities. There is an association between obesity and reduced occupational engagement; however, occupational therapists are underutilized in the field of obesity. Previous research suggests this could be due to occupational therapists receiving a lack of education in obesity. The current study aimed to determine if occupational therapy pre-registration students in the United Kingdom were receiving education in obesity, and what factors influenced whether they received education in obesity. Fifty-nine occupational therapy lecturers from across the United Kingdom completed an online survey. …
Preparing Clinician-Educators: Otd Students' Perceptions Of An Intraprofessional Teaching–Learning Experience, Dianna Lunsford, Anne M. Moscony, Blair Carsone
Preparing Clinician-Educators: Otd Students' Perceptions Of An Intraprofessional Teaching–Learning Experience, Dianna Lunsford, Anne M. Moscony, Blair Carsone
Journal of Occupational Therapy Education
Professional communication and the educator role are essential entry-level competencies in occupational therapy. To date, and to the authors' knowledge, no published study has used an inductive qualitative approach to examine how entry-level occupational therapy doctoral students describe and make meaning of a structured teaching-learning assignment that pairs them with occupational therapy assistant students and casts them in the role of teacher and evaluator. This retrospective qualitative study examined occupational therapy doctoral students' perceptions of a structured peer teaching–learning assignment grounded in the Learning by Teaching framework. Participants included entry-level occupational therapy doctoral students in their final year of study …
Artificial Intelligence: Current Uses In Occupational Therapy Education, Breanna Chycinski, Rebecca Tauber, Brina Crown, Caitlin Noble, Meredith Murphy
Artificial Intelligence: Current Uses In Occupational Therapy Education, Breanna Chycinski, Rebecca Tauber, Brina Crown, Caitlin Noble, Meredith Murphy
Journal of Occupational Therapy Education
Although artificial intelligence (AI) may be an advantageous tool to enhance learning, its societal impacts are still widely unexplored. This study examined how AI is utilized in occupational therapy master’s and doctoral educational programs by faculty and students, while also investigating how such programs are preparing students to employ AI in ethical and beneficial ways. Through the lens of the Person-Environment-Occupation (PEO) Model, this paper examined relationships among occupational therapy students, faculty, their educational environments, and AI. An online survey was distributed to faculty at accredited occupational therapy programs across the United States. Questions included topics such as classroom practices, …
Maladaptive Mindsets In Occupational Therapy Education: A Scoping Review, Steven D. Taff, Lauren Werning, Kim L. Lipsey, Gregory O. Costas, Maribeth Clifton
Maladaptive Mindsets In Occupational Therapy Education: A Scoping Review, Steven D. Taff, Lauren Werning, Kim L. Lipsey, Gregory O. Costas, Maribeth Clifton
Journal of Occupational Therapy Education
In educational settings, maladaptive mindsets refer to negative and counterproductive thoughts or beliefs that can adversely impact one’s ability to learn, engage, and respond to challenges. This scoping review aimed to examine how maladaptive mindsets are represented in occupational therapy education literature and their reported impacts on student learning, mental health, and well-being. Following PRISMA-ScR and established scoping review methodologies, a comprehensive search of six databases yielded 497 unique articles from the last two decades. Only four of the articles met inclusion criteria after screening and full text review. Data was extracted from the four selected articles and analyzed using …
Playfulness, Leisure Motivation, And Coping Skills As Contributors To Graduate Health‑Professions Academic Performance, Amiya Waldman-Levi, Ruth Peer, Noah Frydman, Piermiline Datilus, Suzan Khavkin, Anita Bundy
Playfulness, Leisure Motivation, And Coping Skills As Contributors To Graduate Health‑Professions Academic Performance, Amiya Waldman-Levi, Ruth Peer, Noah Frydman, Piermiline Datilus, Suzan Khavkin, Anita Bundy
Journal of Occupational Therapy Education
Poor mental health affects graduate allied health students’ academic performance. Playfulness, leisure motivation, coping skills, and engagement in leisure activities may contribute to coping with academic stressors. The purpose of this study was to understand the role of leisure participation, playfulness, coping strategies, and anxiety on academic performance of entry-level graduate health professions students. We used a mixed method, exploratory, correlational cross-sectional design to study the relationships between anxiety, playfulness, leisure motivation, coping skills, and academic performance (grade point average) among 108 entry-level occupational therapy, physical therapy, and speech-language pathology students. Measures included the Intrinsic Leisure Motivation Scale, Adult Playfulness …
Students’ Perceptions Of The Value And Challenges Of Oral Assessment In An Undergraduate Occupational Therapy Programme, Alexa M. Andrew, Rachel Sayers, Kristy Richards
Students’ Perceptions Of The Value And Challenges Of Oral Assessment In An Undergraduate Occupational Therapy Programme, Alexa M. Andrew, Rachel Sayers, Kristy Richards
Journal of Occupational Therapy Education
Oral assessments are used in undergraduate occupational therapy programs to facilitate students’ ability to articulate their professional reasoning in relation to a case scenario. Oral assessments are seen by assessors/lecturers as crucial preparation for fieldwork placement. Oral assessments are known to provoke anxiety among students. The aim of this research was to explore students’ perspectives of the value and challenges of the oral assessment. The method was qualitative and focus groups and individual interviews were used to collect data. Thematic analysis of the transcripts was conducted using a semantic approach. Four themes emerged as a result of the data analysis: …
Understanding Self-Directed Learning Development In Occupational Therapy Students: A Mixed Methods Approach, Adrianne Osmundson, Jenna Heffron
Understanding Self-Directed Learning Development In Occupational Therapy Students: A Mixed Methods Approach, Adrianne Osmundson, Jenna Heffron
Journal of Occupational Therapy Education
Occupational therapy students enter graduate school at different stages of self-directed learning (SDL) readiness, and SDL skills must be explicitly taught. However, limited consensus exists on how SDL skill development should be incorporated into educational experiences. A retrospective parallel convergent mixed methods study was conducted to elicit an understanding of SDL development in a single cohort of master’s level occupational therapy students (n = 29) who participated in weekly SDL labs during their graduate education. The SDL labs were designed using Knowles’ (1975) seminal definition of SDL related to individuals taking the initiative to determine their needs, goals, strategies, and …
Professional Identity Building Scale (Pibs) Development: Measuring Self-Authorship And Dimensions Of Professional Identity In Graduate Students, Anne M. Haskins, Sarah Nielsen, Nicole C. Harris, Adrienne M. Salentiny, Marilyn G. Klug
Professional Identity Building Scale (Pibs) Development: Measuring Self-Authorship And Dimensions Of Professional Identity In Graduate Students, Anne M. Haskins, Sarah Nielsen, Nicole C. Harris, Adrienne M. Salentiny, Marilyn G. Klug
Journal of Occupational Therapy Education
Grounded professional identity is needed for individuals to function successfully within their professions. The purpose of this study was to develop and test a new instrument intended to measure the professional identity of graduate students. Within a recursive methodological design, we developed a 71-item Professional Identity Building Scale (PIBS) based on a new conceptualized combination of Baxter Magolda’s Epistemological Reflection Model phases and Villanueava and Nadelson’s dimensions of professional identity. We pilot tested 129 occupational therapy graduate students at two sites in two states, adjusted the instrument and then retested the PIBS with data from 347 respondents in the same …
Exploring The Influence Of A Longitudinal Small-Group Mentorship Course On Occupational Therapy Graduates’ Professional Identity Formation, Tosh Whitley, Lovejot Mangat, Susan G. Rappolt, Daniela Testani, Siobhan Donaghy, Lynn Cockburn, Sylvia Langlois, Ruheena Sangrar, Eric Lee, Rachel Roby, Erin Knobl, Susan Hannah, Anne Fourt, David Gerstle, Naomi Davids-Brumer, M. Shone Joos
Exploring The Influence Of A Longitudinal Small-Group Mentorship Course On Occupational Therapy Graduates’ Professional Identity Formation, Tosh Whitley, Lovejot Mangat, Susan G. Rappolt, Daniela Testani, Siobhan Donaghy, Lynn Cockburn, Sylvia Langlois, Ruheena Sangrar, Eric Lee, Rachel Roby, Erin Knobl, Susan Hannah, Anne Fourt, David Gerstle, Naomi Davids-Brumer, M. Shone Joos
Journal of Occupational Therapy Education
Professional identity formation is a critical aspect in facilitating the transition of healthcare professionals into entry-level practice. Previous literature has highlighted the benefits of mentorship in shaping professional identity formation among healthcare learners. However, few studies have explored longitudinal small-group mentorship courses on professional identity formation in entry-level occupational therapists. The aim of this study was to explore the perspectives of graduates on whether pre-certification mentorship influenced their professional identity formation. Online surveys, comprising open-ended and fixed-choice questions, were collected from graduates of a professional Master of Science in Occupational Therapy (MScOT) program across four cohorts (2020-2023) who completed a …
Implementing Entrustable Professional Activities: Evaluation And Insights From Undergraduate Occupational Therapy Clinical Practice Education In Singapore, Heidi, Siew Khoon Tan, Gabriel, Wu-Xin Kwek, Corrine, Kar Ling Hoo, Florence, Wai Fong Cheong, Muhammad Rahizan Zainuldin
Implementing Entrustable Professional Activities: Evaluation And Insights From Undergraduate Occupational Therapy Clinical Practice Education In Singapore, Heidi, Siew Khoon Tan, Gabriel, Wu-Xin Kwek, Corrine, Kar Ling Hoo, Florence, Wai Fong Cheong, Muhammad Rahizan Zainuldin
Journal of Occupational Therapy Education
Competency-based education is widely adopted in occupational therapy programs, yet translating broad competency frameworks into authentic clinical assessment remains challenging. Entrustable Professional Activities (EPAs) offer an outcome-oriented approach by integrating multiple competencies into observable clinical tasks. This study evaluated the implementation of a nationwide EPA framework alongside an established competency-based assessment tool within an undergraduate occupational therapy clinical practice education program in Singapore. Guided by the 2018 Ottawa Consensus Framework for Good Assessment, this qualitative evaluation study conducted seven focus group discussions with 18 occupational therapy clinical educators and 12 students who experienced the integrated EPA and competency-based assessment system. …
Psychosocial And Behavioral Health Fieldwork: Impact On Occupational Therapy Assistant Student Stigma And Confidence, Tiffany L. Benaroya, Ann A. Murphy, Michelle Zechner, Meredith Cimmino, Margaret Swarbrick
Psychosocial And Behavioral Health Fieldwork: Impact On Occupational Therapy Assistant Student Stigma And Confidence, Tiffany L. Benaroya, Ann A. Murphy, Michelle Zechner, Meredith Cimmino, Margaret Swarbrick
Journal of Occupational Therapy Education
This study examined the impact of psychosocial and behavioral health fieldwork experiences on occupational therapy assistant students’ attitudes toward individuals with serious mental illness and their confidence in working with this population. The study compared different fieldwork experiences among 30 occupational therapy assistant students from multiple cohorts to assess potential changes in stigmatizing attitudes and confidence across four different measures: the Attribution Questionnaire – 9, the Mental Illness Clinician’s Attitudes Scale v 4, the Knowledge Test of Mental Illness, and the Student Confidence Questionnaire. Repeated measures ANOVA indicated a statistically significant reduction in stigma from pre- to post-placement (p=0.04) on …
Occupational Therapy Assistant Students’ Perceptions Of Level I Fieldwork Instructional Methods: A Mixed Methods Study, Tiffany L. Benaroya, Susan M. Higgins
Occupational Therapy Assistant Students’ Perceptions Of Level I Fieldwork Instructional Methods: A Mixed Methods Study, Tiffany L. Benaroya, Susan M. Higgins
Journal of Occupational Therapy Education
Level I fieldwork is a cornerstone of occupational therapy assistant (OTA) education. Placement shortages have prompted OTA programs to expand instructional methods beyond traditional methods to include standardized patients, faculty-led site visits, simulated and virtual environments, and non-traditional placements. Limited research has examined OTA student perceptions of these instructional methods. Therefore, this study explored OTA student preferences, recommendations for future use, and perceived strengths and challenges of Level I fieldwork instructional methods. Nineteen OTA students completed surveys in Fall 2023 and Fall 2024 in this retrospective mixed methods study. Students ranked instructional methods directly experienced in Level I fieldwork: traditional …
Nbcot First-Time Pass Rates At A Hispanic-Serving Institution: The Role Of Academic Metrics And Primary Language, Timothy Tu
Journal of Occupational Therapy Education
This retrospective study examined academic and demographic predictors of first-time success on the National Board for Certification in Occupational Therapy (NBCOT) exam among graduates (N = 82) from the classes of 2019 through 2022 at a Hispanic-Serving Institution. Despite demographic growth, Hispanic and linguistically diverse practitioners remain underrepresented in the profession. Analyzed variables included self-reported primary language, undergraduate GPA (UGPA), prerequisite GPA (PGPA), Graduate Record Examination (GRE) scores, and Occupational Therapy Knowledge Exam (OTKE) performance. Univariate and multivariate logistic regression analyses were conducted using SPSS 31. Three factors significantly predicted first-time NBCOT pass status: UGPA (p = .010), OTKE scores …
Sustaining A High-Fidelity Simulation Assessment For Fieldwork Readiness: A Process Description And Quality Assurance Process, Mary K. Thelander, Sue Iliff, Geneva L. Nolan, Heidi M. Sanders
Sustaining A High-Fidelity Simulation Assessment For Fieldwork Readiness: A Process Description And Quality Assurance Process, Mary K. Thelander, Sue Iliff, Geneva L. Nolan, Heidi M. Sanders
Journal of Occupational Therapy Education
Occupational therapy students often report feeling underprepared for the complex and integrative demands of Level II fieldwork, prompting increased use of simulation-based approaches to support clinical readiness. This process description outlines the design, implementation, and sustained quality assurance of the Occupational Therapy Student Performance Assessment (OTSPA), a multimodal, high-fidelity simulation required before fieldwork in a Southwestern occupational therapy graduate program. Grounded in a problem-based learning framework, the OTSPA integrates multiple levels of simulation fidelity and requires students to complete a full-cycle clinical experience, including referral review, interaction with a standardized patient, documentation, and intervention planning. Faculty evaluate performance using structured, …
Reimagining Level I Fieldwork: A Virtual Home-Based Observation Model In Occupational Therapy Education, Tara Mansour, Colleen Muse, Nicole Williams, Rachel Pittmann
Reimagining Level I Fieldwork: A Virtual Home-Based Observation Model In Occupational Therapy Education, Tara Mansour, Colleen Muse, Nicole Williams, Rachel Pittmann
Journal of Occupational Therapy Education
Fieldwork is essential to occupational therapy education, yet placement demand and constraints on clinician capacity require programs to consider innovative approaches to practice-based learning. Home-based practice is especially difficult to offer as a traditional Level I placement because of travel and space constraints inherent to how services are delivered. This educational innovation describes and evaluates a structured virtual home-based Level I fieldwork model implemented through a partnership between an entry-level occupational therapy program and a national rehabilitation provider. Students completed five live virtual observations of services delivered in clients' living environments. The model, now in its fifth year, incorporated prebriefing, …
Crispr-Cas9 Unleashed: Gene-Slicing Adventures In The Cancer Battlefield, Shivakuma Sonnaila, Shilpi Agrawal
Crispr-Cas9 Unleashed: Gene-Slicing Adventures In The Cancer Battlefield, Shivakuma Sonnaila, Shilpi Agrawal
Chemistry & Biochemistry Faculty Publications and Presentations
Cancer, a global health menace, continues to pose significant challenges in terms of incidence and mortality, necessitating innovative therapeutic strategies. Despite existing treatments, the limitations persist, prompting a quest for novel approaches. The emergence of immunotherapy marked a transformative era in solid tumor treatments, yet its efficacy is constrained by adverse effects. Concurrently, the integration of advanced technologies into cancer treatment explores the vast potential residing at the molecular level through gene analysis and manipulation. This review articulates the role of state-of-the-art genome editing technology, notably clustered regularly interspaced short palindromic repeats (CRISPR-Cas9), in overcoming the constraints of immunotherapy for …
Reclaiming Sophia In The Age Of Ai: Theological And Ethical Reflections On Consecrated Technology And Human Dignity, Matthew H. Sauber
Reclaiming Sophia In The Age Of Ai: Theological And Ethical Reflections On Consecrated Technology And Human Dignity, Matthew H. Sauber
Faculty Scholarship 2026
The cultural emergence of artificial intelligence systems named after figures of divine wisdom—most notably the Hanson Robotics humanoid Sophia, granted Saudi citizenship in 2017—reveals a gap between the language of the wisdom traditions and that of contemporary technology. This paper treats that gap as the occasion for theological and ethical reflection on AI. Drawing on the Sophia tradition across its Hebrew, Hellenistic-Patristic, Gnostic, Russian Sophiological, perennialist, and Sufi articulations—especially Sergei Bulgakov’s account of Sophia as mediation between divine wisdom and created order—it develops a framework termed Consecrated Technology. The argument unfolds in three moves: (1) a structural critique showing how …
Rsif Burkina Faso Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif Burkina Faso Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Burkina Faso has placed human capital development and structural economic transformation at the center of its development agenda. The country’s National Development Plan 2026–2030 (Plan RELANCE) seeks to build a sovereign and prosperous nation through endogenous and sustainable development, with priorities that include strengthening human capital, productive sectors and infrastructure. These ambitions require a stronger base of scientists, engineers and innovators capable of supporting the country’s transformation.
Burkina Faso has demonstrated its commitment to strengthening advanced scientific capacity through its participation in PASET-Rsif since 2020. As one of the nine African governments contributing to the Regional Scholarship and Innovation Fund, …
Rsif Ghana Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Ghana Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Ghana's development agenda puts science, technology and innovation (STI) at the centre of its plans for a more productive, diversified, knowledge-driven economy. The Medium-Term National Development Policy Framework 2026–2029 names two constraints on industrial development: low investment in research and development (R&D), and a shortage of skilled industrial personnel. In response, it calls for greater use of applied research, more R&D investment and industry-relevant skills. The 2026–2029 Medium-Term Development Plan for science and technology and the National STI Policy support these goals. They call for mainstreaming STI across sectors, expanding tertiary STEM education and strengthening research infrastructure and institutional capacity. …
Rsif CôTe D'Ivoire Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif CôTe D'Ivoire Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Côte d’Ivoire’s National Development Plan (PND) 2026–2030 seeks to accelerate the country’s transformation through industrialization, increased productivity, human capital development and private-sector growth. Priority areas include agriculture and agro-industry, digital transformation, and infrastructure and industrial development, all of which increasingly depend on strong scientific and technological capabilities.
Côte d’Ivoire has been investing in PASET-Rsif since 2019, with an initial contribution of USD 1 million to support advanced doctoral training for Ivorian scientists. To date, 11 Ivorian scholars are pursuing PhD training across selected African Host Universities, complemented by research placements and collaboration with international partner institutions. The scholars are developing …
Rsif Kenya Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Kenya Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Kenya's Vision 2030 aims to turn the country into a competitive, industrializing, knowledge-based economy. The Fourth Medium Term Plan (MTP IV) 2023–2027 advances this goal by prioritizing agriculture, micro, small and medium enterprises (MSMEs), housing, healthcare, and the digital and creative economy. MTP IV treats science, technology and innovation (STI) and human capital as key enablers of transformation. It also names several weaknesses in the STI system: too little investment in research and development, limited commercialization of local innovations, and weak links between research and industry.
To address these gaps, Kenya needs a critical mass of highly qualified scientists, engineers …
Rsif Mozambique Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif Mozambique Country Report 2026 - English, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Mozambique is endowed with significant natural resources, including arable land, water, energy and minerals, and occupies a strategic position as a logistics corridor in Southern Africa. Transforming these assets into inclusive and sustainable economic growth will increasingly depend on the country’s ability to develop a highly skilled workforce, strengthen its scientific and technological capabilities, and translate research and innovation into solutions for national development.
Mozambique joined PASET in 2019, reinforcing the country’s commitment to developing the advanced scientific and technical skills needed to support its national development ambitions. The Government subsequently committed USD 6 million to Rsif through the World …
Rsif Nigeria Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Nigeria Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Nigeria's long-term ambition, set out in Nigeria Agenda 2050, is to become an upper-middle-income, diversified and knowledge-driven economy. The Medium-Term National Development Plan (MTNDP) 2026–2030, now being finalized, is the main vehicle for that goal. These frameworks prioritize economic diversification away from oil, industrialization, agricultural productivity, digital transformation, and human capital development. Science, technology and innovation (STI) is treated as a key driver across all of them. Nigeria's National Science, Technology and Innovation Policy also calls for more investment in research and development, stronger links between research and industry, and wider commercialization of local innovations.
Nigeria is one of the …
Rsif Senegal Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Senegal Country Report 2026, Regional Scholarship And Innovation Fund (Rsif)
Rsif Country Progress Reports
Senegal’s Vision 2050, operationalized through the National Development Strategy (SND) 2025–2029, sets an ambitious pathway towards a more sovereign, competitive and resilient economy. The agenda prioritizes productive transformation, industrialization and local value addition, human capital development, digital transformation and sustainable development, with research and innovation positioned as important enablers of national transformation.
Senegal is a founding member of PASET and has been contributing to Rsif since 2020. The country committed USD 2 million (Fig.1) through the World Bank-supported Africa Centres of Excellence for Higher Education for Development Impact (ACE Impact) project to support advanced doctoral training for Senegalese scientists. This …
Moringa Oleifera As An Immunomodulator, Noha Swilam, Khaled A. Nematallah, Omayma Eldahshan'
Moringa Oleifera As An Immunomodulator, Noha Swilam, Khaled A. Nematallah, Omayma Eldahshan'
Pharmacy
Moringa oleifera has gained increasing attention for its diverse pharmacological properties, including its potential to modulate immune responses. This chapter explores the immunomodulatory potential of M. oleifera, exploring both its phytochemical composition and experimental evidence from in vitro and in vivo studies. Key bioactive constituents, such as flavonoids (quercetin, kaempferol, apigenin), phenolic acids (chlorogenic, ferulic, caffeic), glucosinolates (glucomoringin) and their hydrolysis product, benzyl isothiocyanate, are identified as contributors to its immune-regulating properties. It has been demonstrated that these substances affect cytokine expression, suppress pro-inflammatory mediators, increase phagocytic activity and alter lymphocyte reactions. In order to support the plant's traditional use …
Comparative Bioassay-Guided Fractionation Of Citrus Species: Phytochemical Characterization And Nanoformulation Of A Polyphenol-Rich Leaf Fraction From Citrus Aurantifolia For Skin Anti-Aging Applications, Noha Swilam, Khaled A. Nematallah, Amgad Albohy, Noha M. Badawi, Sameh S. Gad, Maha M. Shouman, Saeed S. Al-Ghamdi, Nahla Ayoub
Comparative Bioassay-Guided Fractionation Of Citrus Species: Phytochemical Characterization And Nanoformulation Of A Polyphenol-Rich Leaf Fraction From Citrus Aurantifolia For Skin Anti-Aging Applications, Noha Swilam, Khaled A. Nematallah, Amgad Albohy, Noha M. Badawi, Sameh S. Gad, Maha M. Shouman, Saeed S. Al-Ghamdi, Nahla Ayoub
Pharmacy
Background: Skin aging is driven by oxidative stress and ultraviolet (UV) exposure, leading to extracellular matrix degradation and loss of skin elasticity. This study aimed to identify the most biologically active Citrus species using a bioassay-guided approach and evaluate its potential for dermal applications. Methods: Hydroalcohol extracts and ethyl acetate fractions of Citrus sinensis, Citrus aurantifolia, and Citrus reticulata leaves were screened for antioxidant, enzyme-inhibitory, and polyphenol content. The most active fraction was characterized by UPLC-PDA and LC–MS/MS, formulated into Span-based nanovesicles, and evaluated for physicochemical properties and drug release. Biological activity was assessed using an in vitro scratch wound-healing …
Role Of Plants And Phytochemicals In Promoting Proliferation And Osteogenic Differentiation Of Dental Mesenchymal Stem Cells: A Comprehensive Review, Hala El-Zahar, Essam Abdel-Sattar, Marwa Yousry Moustafa Issa, Shereen N. Raafat, Noha Swilam
Role Of Plants And Phytochemicals In Promoting Proliferation And Osteogenic Differentiation Of Dental Mesenchymal Stem Cells: A Comprehensive Review, Hala El-Zahar, Essam Abdel-Sattar, Marwa Yousry Moustafa Issa, Shereen N. Raafat, Noha Swilam
Pharmacy
Abstract Objectives Dental mesenchymal stem cells (MSCs) represent a promising source for regenerative medicine due to their accessibility and capacity to differentiate into osteoblasts and other lineages. Osteogenic differentiation of dental MSCs is essential for bone formation and is regulated by multiple signaling pathways, cytokines, growth factors, and transcription factors. This review aims to summarize the effects of plant-derived extracts and phytochemicals on the proliferation and osteogenic differentiation of dental MSCs. Methods In this review, an extensive literature search was conducted covering studies from the past 10 years, using different online databases (SCOPUS, Google Scholar, PubMed, Web of Science, Science …