Towards The Development Of Targeted And Quantitative Mass Spectrometry Methods For The Investigation Of Biological Systems, William Gazlay

Graduate Doctoral Dissertations

Mass spectrometry has become an essential analytical platform for the characterization of complex biological systems, enabling detailed investigation of molecular structure, post-translational modifications, and protein expression. This dissertation applies modern mass spectrometry methodologies to three analytical challenges spanning lipidomics and proteomics.

The first study examined the influence of complexing agents on the sensitivity of collision-induced dissociation (CID) spectra to fatty acid position in synthetic XYZ-type triglycerides. Comparison of ammonium, lithium, and sodium adducts demonstrated that alkali metal adducts provide substantially improved positional sensitivity and greater consistency across triglyceride systems. These findings support the use of lithium and sodium adducts for …

Motor Imagery Eeg Decoding For Brain-Computer Interfaces: Structured Representation, Transfer, And Drift, Yiming Shen

Graduate Doctoral Dissertations

Motor imagery EEG decoding is often summarized by the accuracy of a final classifier, but the classifier is only the last stage of the pipeline. Before classification, the signal has already been shaped by preprocessing, feature extraction, source-session organization, and adaptation. This dissertation studies how feature representation, source-session transfer, and drift shape reliable MI-EEG decoding for brain-computer interfaces.

It first studies within-session decoding on public MI-EEG datasets using nested validation that keeps preprocessing, feature fitting, and model selection inside the training folds. This analysis separates gains from feature representation from gains due to nonlinear classification, and relates both comparisons to …

The Grasshopper's Journey To The Bloch Sphere, David Llamas

Graduate Doctoral Dissertations

The Grasshopper Problem asks a simple geometric question. A grasshopper lands on a lawn of fixed area and jumps a fixed distance in a random direction. What shape of lawn maximizes the probability that the grasshopper remains on the lawn after jumping? The jump rule is rotationally symmetric, but the best lawns do not have to be. This dissertation studies how that symmetry breaking occurs, maps the continuum problem to a novel constrained spin system, and uses the spherical Grasshopper Problem to compare quantum singlet correlations with classical local models.

For planar lawns, boundary-integral and perturbative calculations explain why the …

Gendered Precarity, Informality And Survival Among Cambodian Women Migrants In Thailand, Sokha Eng

Graduate Doctoral Dissertations

Migration scholars have long assumed that women migrant laborers move as individuals, leave family behind, are governed by labor migration policies, and are employed full-time. However, in the context of South-South migration, many workers migrate as families, with husbands, wives, and sometimes even children. Some engage in the informal economy, serving as casual and on-call workers. These types of employment fall outside the scope of standard labor migration policies and therefore receive less attention. As a result, migrants’ experiences in such work arrangements remain underexplored. This study examines the experiences of Cambodian migrant women in Thailand by examining the case …

The Role Of Critical Professional Development In Transforming The Teaching And Learning Practices Of White Faculty: Elevating Racial Consciousness To Center Equity, Kaitlyn E. Siner-Cappas

Graduate Doctoral Dissertations

The purpose of this study was to explore the experiences of white faculty participants in a critical professional development (CPD) program that seeks to enhance racial consciousness at a public research university. The goal of the study was to understand any perceived changes in faculty positionality and teaching and learning practices following their participation in the program, as well as identify the extent to which the program supported participants in a journey towards enhanced racial consciousness.

Four themes characterized the experiences of faculty participants in this CPD program: 1) experiencing the benefits of a learning community, 2) gaining confidence in …

Redesigning Quantum Theory, Matthew Weiss

Graduate Doctoral Dissertations

QBism understands quantum mechanics to be probability theory supplemented by additional nonclassical coherence conditions. In this dissertation, we develop these nonclassical coherence conditions from first principles, emphasizing the role of a well chosen reference measurement. After treating standard probability on subjective Bayesian lines, we demonstrate an equivalence between the QBist approach and the existing framework of generalized probabilistic theories. We show that the fundamental nonclassical coherence relation may almost always be taken to be a gentle modification of the law of total probability, and give a coherentist account of when an experimental scenario has a classical explanation. Finally, we show …

Traversing The Broken Staircase: The Experiences Of Academic Neglect For Black & Brown First-Generation College Students, Kashmeel D. Mckoena

Graduate Doctoral Dissertations

Although Black and Brown students are diversifying college campuses and opening doors for their families as new cohorts of first-generation collegians, they often find themselves silently dealing with the aftermath of academic neglect from U.S. secondary education. This phenomenon can be understood from extant literature as absence of reliable guidance, mentorship, resources, and support that help students persist and succeed in their academic goals. Existing explanations of grit and resilience (Duckworth et al., 2007) not only erase the existence and impact of academic neglect, but also mask the creative solutions and compensatory strategies that Black and Brown first-generation college students …

A Statistical Mechanics Approach To Reinforcement Learning, Jacob Adamczyk

Graduate Doctoral Dissertations

Reinforcement learning (RL), the study of optimal decision-making over long timescales in stochastic systems, has recently seen remarkable advances due in large part to the efforts of the deep learning community. RL has witnessed great success in solving problems in video games, robotics, biological control, and language modeling. However, a unified statistical mechanics framework to understand and develop the corresponding algorithms is lacking. To address this issue, we begin by showing that the reinforcement learning problem can be formulated and solved using the tools of statistical mechanics. Drawing on physical principles of free energy minimization and invariance, we address important …

Equitable Access To Literacy Assessment And Instruction For Students With Cerebral/Cortical Visual Impairment, Tammy Reisman

Graduate Doctoral Dissertations

Students with Cerebral/Cortical Visual Impairment (CVI) represent a growing population of learners whose visual difficulties originate in the brain rather than the eyes. As understanding of CVI has evolved, questions have emerged regarding the most appropriate approaches to literacy assessment and instruction. While some educational approaches emphasize maximizing visual functioning, increasing evidence supports the integration of compensatory skills and multiple sensory channels to improve literacy access. Understanding current literacy assessment and instructional practices is essential to ensuring equitable educational opportunities for students with CVI.

The purpose of this mixed-methods study was to examine current literacy assessment and instructional practices for …

Process And Change In The Global Governance Of Sustainable Development, S. Beth Fascitelli

Graduate Doctoral Dissertations

In 2015, to euphoric acclaim, the world adopted the 2030 Agenda for Sustainable Development. But with less than five years to deliver its seventeen Sustainable Development Goals (SDGs), the Agenda’s “transformational vision” remains unrealized. To understand why, this dissertation looks not to the Agenda’s implementation but to its birth, asking how the three-year process that produced it was designed, implemented, and experienced, and whether its mechanisms reinforced or challenged the structures that shape global sustainability governance. The premise is simple: how global agreements are negotiated matters as much as their substance. The study thus pushes back against a celebratory view …

Redefined: Understanding The Experience Of Black Joy Among Black Youth, Kaela A. Yamini

Graduate Doctoral Dissertations

The study of Black joy is a newer concept and, therefore, reflected in a small but growing body of literature. Many scholars have reflected on the theoretical nature of Black joy and how it can appear across settings, e.g., academically, occupationally, communally, and internally, but very few studies have examined this phenomenon empirically. Several definitions of Black joy have emerged in connection to history and suffering; however, there is still a notable lack of agreement among researchers. Despite that, all conceptualizations acknowledge how this emotional experience is much greater than the pain associated with it and highlight its ability …

“Nothing About Us Without Us”: Examining Sense Of Belonging And College Success Through The Experiences Of Students With Autism Spectrum Disorder, Courtney E. Mulligan

Graduate Doctoral Dissertations

Sense of belonging has become an increasingly important indicator of student engagement, persistence, and success in higher education. Despite this, limited research has explored how college students with autism experience and define belonging while at college. As increasing numbers of students with autism pursue postsecondary education, institutions face a growing need to better understand the factors that influence student experiences and outcomes. The purpose of this mixed-methods study was to investigate the experiences of sense of belonging among current college students with autism and identify the factors that contribute positively or negatively to this experience to inform more inclusive higher …

The Negotiated Identities Of Refugee-Background Women During Resettlement, Iuliia Fakhrutdinova

Graduate Doctoral Dissertations

Refugee-background women experience unique challenges while resettling in the U.S. as they navigate complicated transnational gender roles, education gaps, migration trauma, learning a new language, and literacy in the adaptation process during resettlement, which can derail the productive paths they are on. Therefore, ignoring refugee-background women’s unique experiences and failing to understand their identities prevents our society from doing social justice and creating a space for a smooth adaptation to the new context. Language plays a paramount role in identity formation, as it moves away from the belief that identity is an essential concept. For refugee-background women during resettlement, their …

Social Experiences Of Chinese International Students At A Us Liberal Arts College, Ke Yao

Graduate Doctoral Dissertations

This study provided detailed empirical evidence on social experiences of Chinese international students within a US liberal arts college context through examining their race, culture, gender, social class, and mental health experiences. This study showed that the experiences of Chinese international students in the US higher education institutions are influenced not only by individual adaptation but also by broader social and institutional contexts. First, findings of this study demonstrated that institutional features of liberal arts colleges, such as small campus environment, residential nature, and more interactive opportunities between domestic and Chinese international students, can simultaneously create opportunities for inclusion and …

Factorial Structure Of A Bilingual Progress Monitoring Tool For Mindfulness Interventions, Andrea V. Molina Palacios

Graduate Doctoral Dissertations

Mindfulness-based interventions (MBIs) are an increasingly popular option for schools to support youth in each of the multi-tiered systems of support (MTSS). MBIs have proven to increase attention, help with emotion regulation, decrease symptoms of anxiety and depression, and overall increase students’ wellbeing with a cost-effective package that makes it affordable for schools to implement. Moreover, MBIs have also proven to be effective for Hispanic youth who are at a higher risk of experiencing low access to mental health care and higher levels of poverty, which puts them at risk for dropping out and having low academic achievement. However, there …

The Anti-Racist Organization? Power, Embodiment, And The Politics Of Becoming, Patricia Tiimah Naya

Graduate Doctoral Dissertations

Why do organizational justice commitments so rarely produce structural transformation, and what happens to the people who take them seriously? This dissertation addresses that question through a longitudinal qualitative study of Aequitas University, a large public urban research institution in the northeastern United States, during a multi-year attempt to become “anti-racist.” Drawing on 129 semi-structured interviews with 115 organizational members, 7 focus group discussions, four years of field observation, and an archival corpus spanning more than a decade of institutional history, the dissertation examines how justice commitments move through organizations over time. Justice commitments do not simply succeed or fail. …

Genomic Based Environmental Health Assessment: Vieques, Puerto Rico, Valeria Hernandez Talavera

Graduate Doctoral Dissertations

From 1941 to 2003, the United States Navy and North Atlantic Treaty Organization (NATO) used Vieques, Puerto Rico, for military training, which led to long-term pollution from metals, organic chemicals, explosives, and per- and polyfluoroalkyl substances (PFAS). While earlier research found these contaminants in the environment and in living organisms, their combined effects on local ecosystems remain poorly understood.

This dissertation used a Genomic-Based Environmental Health Assessment (GEHA) framework to study the ecological risks from past military pollution in Vieques. The approach combined sediment toxicity tests, chemical analysis, gene expression studies, microbial community analysis, and community-based research. The four main …

From Structure To Experiences: How Facility Capacity And Staffing Shape The Adoption And Impact Of Lgbt-Affirming Policies In Long-Term Care, Andrew Alberth

Graduate Doctoral Dissertations

Long-term care (LTC) settings – including nursing homes (NHs) and assisted living facilities (ALFs) – provide necessary care for individuals with extreme health and functioning limitations. Sexual and gender minority (LGBT) older adults report challenges receiving effective, person-centered care LTC. Some LGBT older adults may hide their sexual orientation and gender identity when entering LTC settings or delay seeking needed LTC fearing discrimination from staff and other residents. Furthermore, staff in LTC settings indicate little awareness of LGBT-residents and possess inadequate LGBT-cultural competency necessary for providing person-centered care. Therefore, LGBT-residents LTC experiences remain underexplored in the broader research. Adopting LGBT-affirming …

Identifying Discrete Reappraisals And Examining The Properties Of Cognitive Reappraisal That Predict Emotional Outcomes, Jenny L. Wu

Graduate Doctoral Dissertations

Cognitive reappraisal is widely regarded as an adaptive emotion regulation strategy and a central strategy to promote cognitive change in psychological treatments. However, findings regarding its effectiveness have been inconsistent, potentially due to the tendency to conceptualize reappraisal as a uniform process. The present study sought to adopt a more fine-grained, process-oriented approach by examining variability in how reappraisal is implemented. Specifically, this study investigated (1) the overall effectiveness of cognitive reappraisal, (2) whether the perceived believability of reappraisals predicts emotional outcomes, and (3) whether different types of reappraisals are associated with differences in emotional outcomes. Participants completed a modified …

Home, Neighborhood, And Community Environments And Social Isolation In Later Life: Joint Associations And Their Moderation By Life-Course Socioeconomic Mobility, Jeein Law

Graduate Doctoral Dissertations

Social isolation is a major public health concern among older adults, yet less is known about how multilevel residential environments shape isolation among those aging in place. Guided by the Socio-Ecological Model, Person–Environment Fit, and a life-course perspective, this dissertation examined whether micro-level home hazards, meso-level neighborhood social cohesion and physical disorder, and macro-level census-tract structural conditions were associated with social isolation. It also examined whether life-course socioeconomic mobility moderated the associations between home and neighborhood environments and social isolation.

This dissertation used two nationally representative longitudinal studies of U.S. older adults. Aims 1 and 2 used the National Health …

I Must Be Well, To Do Well: Examining The Relationship Between Toxic Stem Environments, Trauma, Stem Support, And Academic Outcomes Among Diverse Graduate Women In Stem, Aisha Farra

Graduate Doctoral Dissertations

Women, particularly Women of Colour (WOC), remain underrepresented in STEM. In the last two decades, research has sought to better understand women’s experiences in STEM, highlighting challenges such as isolation, sexism, and racism, which negatively impact mental health and STEM persistence. While these mental health challenges have been documented, further work is needed to examine how these experiences are related to trauma symptoms and physical health outcomes, as well as the mechanisms through which they shape academic outcomes. This quantitative study investigated the relationships among toxic STEM experiences (i.e., gendered racism, sexism, and isolation), trauma symptoms and physical health concerns, …

Solving For X: Centering Black Girls’ Experiences In Mathematics Education, Natasha A. Fortes

Graduate Doctoral Dissertations

Black girls can grow up, attend school, and move through their math classes without ever feeling seen as capable mathematical thinkers. Their teachers may not affirm their brilliance. Their voices may even go unheard. Math classes may not be a space where they can imagine themselves belonging. These experiences do not reflect ability. Instead, they reflect on the conditions in which they are expected to learn. This study centers the voices of Black girls and asks what they deserve from their mathematics education and instructors to develop a mathematics identity. The study is grounded in Black feminist traditions and draws …

The Impact Of Childhood Adversity On Students In Urban Public Elementary Schools: Recognizing, Responding, And Implementing Interventions To Support Struggling Students Through In-Depth Conversations With School Leaders, Stephen Shaw-Lyon

Graduate Doctoral Dissertations

THE IMPACT OF CHILDHOOD ADVERSITY ON STUDENTS IN URBAN PUBLIC ELEMENTARY SCHOOLS: RECOGNIZING, RESPONDING, AND IMPLEMENTING INTERVENTIONS TO SUPPORT STRUGGLING STUDENTS THROUGH IN-DEPTH CONVERSATIONS WITH SCHOOL LEADERS

August 2026

Stephen P. Shaw-Lyon, A.A., Massasoit Community College

B.A., Arizona State University

M.Ed., Fitchburg State University

C.A.G.S., Bridgewater State University

Ph.D., University of Massachusetts Boston

Directed by Assistant Professor Bodunrin Banwo

This dissertation explores how adverse childhood experiences (ACEs) affect students in urban public elementary schools in Massachusetts. While the original ACE Study reshaped understanding of adult health outcomes, less research examines how trauma influences children’s academic, behavioral, and social experiences in …

Governing Climate Change For Sustainable Food Security In The Busoga Region Of Uganda, James Kintu

Graduate Doctoral Dissertations

Busoga, Uganda's most sugarcane-intensive sub-region, hosts seven mills and an expanding outgrower economy, yet remains among Uganda's most food-insecure areas, with over half of its households food-insecure. This study examined how governance of climate change and sugarcane expansion shapes capabilities for food access, land tenure, and decision-making among women, youth, and land-poor households in Jinja and Buyende.

The study developed an integrated CA-CEP-RFS framework, combining the Capability Approach, Comparative Environmental Politics, and the Resilient Food Systems framework, with Sen's Entitlement Framework bridging capabilities to production, trade, own-labor, and transfer entitlements. A qualitative case study drew on a documentary review, 27 …

Understanding Factors Influencing Multiple Tobacco Product Use Among Adolescents In Thailand: A Structural Equation Modeling Approach, Chaowalit Srisoem

Graduate Doctoral Dissertations

Tobacco use among Thai adolescents is shaped by personal, environmental, and product-related factors. However, the pathways linking these influences to actual behavior remain unclear. This study examined how personal, environmental, and product-related factors, along with intentions to use, relate to tobacco use among Thai adolescents. A cross-sectional secondary analysis was conducted using data from the 2022 Thailand Global Youth Tobacco Survey of 6,235 students aged 13–15 years. Survey weights methods were applied to produce nationally representative estimates. Confirmatory factor analysis and structural equation modeling assessed latent constructs, and multinomial logistic regression examined predictors of single, dual, and multiple product use. …

Multicomponent Reaction-Initiated Synthesis Of Polyheterocyclic Compounds, Ashutosh Nath

Graduate Doctoral Dissertations

Efficient synthesis of novel heterocycles with biological interest remains a challenge in modern organic chemistry. This dissertation presents the development of efficient synthetic strategies that combine multicomponent reactions (MCRs) with sequential reactions for rapid access a diverse array of polyheterocyclic compounds. The projects are: 1) Groebke-Blackburn-Bienaymé (GBB) reaction followed by N-acylation and Friedel-Crafts (FC) cyclization for the construction of imidazopyridine- and indole-fused azepinones involving an unusual ring-expansion process. 2) Modified GBB condensation products for intramolecular Diels-Alder (IMDA) cycloaddition and dehydrative re-aromatization to access imidazopyridine-fused isoquinolinones. 3) Integration of the Ugi-three component reaction (Ugi-3CR) and Pictet-Spengler (PS) reaction followed by …

The Effect Of State Policy On Individuals With Mental Illness In Nursing Homes: A Multilevel Analysis, Adrita Barooah

Graduate Doctoral Dissertations

ABSTRACT

THE EFFECT OF STATE POLICY ON INDIVIDUALS WITH MENTAL ILLNESS IN NURSING HOMES: A MULTILEVEL ANALYSIS

August 2026

Adrita Barooah, B.Sc., University of Delhi, India

M.S., University of Massachusetts Boston

Ph.D., University of Massachusetts Boston

Directed by Professor Pamela Nadash

The proportion of individuals living with a mental illness in U.S. nursing homes has grown substantially over the past few decades (Fashaw et al., 2020), raising serious concerns about care quality, resource adequacy, and costs to both nursing homes and government payers. The lack of adequate resources and knowledge has resulted in sub-par mental health care (O'Connor et al., …

Middle Class Affordability In The Mountain West, 2023, Kian Parikh, Krish Sharma, Mohit Pande, Kristian Thymianos, Caitlin J. Saladino, William E. Brown Jr.

Economic Development & Workforce

This fact sheet presents 2023 data on the share of middle-class households that can afford basic necessities in the five Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The Brookings Institution report, “In every corner of the country, the middle class struggles with affordability,” provides metropolitan-level estimates across all 50 U.S. states and the District of Columbia. This fact sheet focuses on middle class affordability data for the largest metro area in each Mountain West state and, where available, explores middle class affordability by race and ethnicity.

The Rider (2026-08-31), Daniela Chapa-Reyes

The Rider Archives

Vol. 12, No. 2

Innovating A Crustacean Embryo Toxicity (Cet) Assay For Screening Environmental Contaminants, Irina A. Polunina-Proulx

Graduate Doctoral Dissertations

Environmental pollutants can disrupt normal developmental processes, leading to neurobehavioral and developmental abnormalities. Toxicity tests are important for evaluating environmental contaminants; however, standard assays are often time- and cost-intensive and typically require large numbers of vertebrate animals. These limitations highlight the need to reduce reliance on vertebrate testing and to develop New Approach Methodologies that provide comparable results while improving efficiency and cost-effectiveness. This research utilizes a novel screening assay to evaluate developmental toxicity using Hyalella azteca. H. azteca is a freshwater amphipod widely used as a model organism for sediment toxicity in ecotoxicology, yet its embryos have been minimally …