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Articles 109741 - 109763 of 109763
Full-Text Articles in Entire DC Network
Diet And Physical Activity Behaviours Among People With Insomnia Symptoms: A Cross-Sectional Survey To Understand Treatment Needs And Acceptability, Jacy Hyland, Moira Junge, Joseph J. Scott, David Cunnington, Mia A. Schaumberg, Mathew J. Summers, Timothy Baird, Claire M. Ellender, Caitlin Fehily, Emma Axelsson, Sara Winter, Jenny Bowman, Hattie H. Wright, Christopher D. Askew, Alexandra P. Metse
Diet And Physical Activity Behaviours Among People With Insomnia Symptoms: A Cross-Sectional Survey To Understand Treatment Needs And Acceptability, Jacy Hyland, Moira Junge, Joseph J. Scott, David Cunnington, Mia A. Schaumberg, Mathew J. Summers, Timothy Baird, Claire M. Ellender, Caitlin Fehily, Emma Axelsson, Sara Winter, Jenny Bowman, Hattie H. Wright, Christopher D. Askew, Alexandra P. Metse
Research outputs 2022 to 2026
Background: High adherence to a Mediterranean diet and regular moderate-intensity physical activity (≥5 days/week, ≥30 minutes/day) reduce the risk of insomnia symptom onset and maintenance, yet engagement in these behaviours among adults with insomnia symptoms and the acceptability of lifestyle support are not well understood.
Methods: Objectives: (1) characterise diet and physical activity behaviours among people with insomnia symptoms, including adherence to the Mediterranean diet and physical activity guidelines (moderate-intensity physical activity on ≥5days/week for ≥30 minutes/day), as well as the regularity of these behaviours; (2) explore clinical and socio-demographic factors associated with these behaviours; and (3) investigate the acceptability …
Early-Life Pathways To Inequalities In Child Mental Health: Evidence From Eight Birth Cohorts, Demetris Avraam, Gabriella Melis, Tim Cadman, Jennie Carson, Marie Aline Charles, Yu Wei Chua, Ahmed Elhakeem, Joaquín Escribano, Veit Grote, Dariusz Gruszfeld, Kathrin Guerlich, Rae-Chi Huang, Jennifer R. Harris, Jesus Ibarluzea, Jordi Julvez, Berthold Koletzko, Ashleigh Lin, Unai Martin, Rosemary Mceachan, Maria Melchior, Phillip Melton, Johanna Thorbjornsrud Nader, Angela Pinot De Moira, Maja Popovic, Simona Porru, Lorenzo Richiardi, Blanca Sarzo, Daniela Schlüter, Jordi Sunyer, Morris Swertz, Elvira Verduci, John Wright, Annick Xhonneux, Tiffany Yang, Daniela Zugna, Anne-Marie Nybo Andersen, Katrine Strandberg-Larsen, David Taylor-Robinson
Early-Life Pathways To Inequalities In Child Mental Health: Evidence From Eight Birth Cohorts, Demetris Avraam, Gabriella Melis, Tim Cadman, Jennie Carson, Marie Aline Charles, Yu Wei Chua, Ahmed Elhakeem, Joaquín Escribano, Veit Grote, Dariusz Gruszfeld, Kathrin Guerlich, Rae-Chi Huang, Jennifer R. Harris, Jesus Ibarluzea, Jordi Julvez, Berthold Koletzko, Ashleigh Lin, Unai Martin, Rosemary Mceachan, Maria Melchior, Phillip Melton, Johanna Thorbjornsrud Nader, Angela Pinot De Moira, Maja Popovic, Simona Porru, Lorenzo Richiardi, Blanca Sarzo, Daniela Schlüter, Jordi Sunyer, Morris Swertz, Elvira Verduci, John Wright, Annick Xhonneux, Tiffany Yang, Daniela Zugna, Anne-Marie Nybo Andersen, Katrine Strandberg-Larsen, David Taylor-Robinson
Research outputs 2022 to 2026
Background: Socioeconomic inequalities in children's emotional and behavioural problems are already present at school entry. We examined associations between early-life socioeconomic conditions and children's externalising and internalising problems and assessed whether early-life risk factors mediated these associations.
Methods: We analysed harmonised individual participant data from eight birth cohorts within the EU Child Cohort Network. Maternal educational level during pregnancy was used as an indicator of early-life socioeconomic conditions (SECs). Scores of children's externalising and internalising problems around school entry age were used as the outcome variables. Inequalities were quantified using the Slope Index of Inequality which captures the difference in …
Employer Perspectives On Graduates’ Professional Identity Formation In The Workplace, Denise Jackson, Michael Tomlinson
Employer Perspectives On Graduates’ Professional Identity Formation In The Workplace, Denise Jackson, Michael Tomlinson
Research outputs 2022 to 2026
Professional identity (PI) is recognised as a crucial dimension in how graduates negotiate the transition to employment and move towards a pathway of sustainable professional development. Perspectives on PI have been derived mainly from higher education students with little attention given to the perspective of employers involved in supporting and supervising graduates in the workplace. Accordingly, the study surveys 339 industry professionals to examine their perceptions of how formed graduates’ PI is at different times after recruitment and the influence of personal, organisational and external factors on identity formation at work. Employers recognised how a well-formed PI enables graduates to …
Fostering Authentic Corporate Social Responsibility Through Place-Based And Relational Methodologies In Mining Governance: A Global Synthesis, Mehran Nejati, Eduardo Ordonez-Ponce, Rumen Rachev, Belen Lopez Vazquez
Fostering Authentic Corporate Social Responsibility Through Place-Based And Relational Methodologies In Mining Governance: A Global Synthesis, Mehran Nejati, Eduardo Ordonez-Ponce, Rumen Rachev, Belen Lopez Vazquez
Research outputs 2022 to 2026
Purpose: As the global economy shifts towards low-carbon development, sustainable mining practices are becoming increasingly vital for balancing resource extraction with environmental and social responsibilities. This study aims to critically evaluate how traditional corporate social responsibility (CSR) frameworks fall short in addressing power asymmetries and territorial impacts, and to explore how place-based and relational methodologies can foster authentic corporate social responsibility (ACSR) in mining governance.
Design/methodology/approach: This review synthesises findings from 77 peer-reviewed studies published between 2015 and 2025, covering diverse global mining contexts. The analysis identifies transformative themes through a qualitative meta-synthesis approach, focusing on governance practices that empower …
From Awareness To Articulation: How Character Strengths Support Wellbeing Literacy In Pre-Service Teachers, Narelle Lemon, Marnie Harris, Rozita Dass, Carli Sanbrook, Rikki James, Tammy Green, Bev Adkin, Gail Berman
From Awareness To Articulation: How Character Strengths Support Wellbeing Literacy In Pre-Service Teachers, Narelle Lemon, Marnie Harris, Rozita Dass, Carli Sanbrook, Rikki James, Tammy Green, Bev Adkin, Gail Berman
Research outputs 2022 to 2026
Teacher wellbeing demands urgent attention given documented attrition and burnout, yet teacher education programmes often treat wellbeing as peripheral to professional preparation. Sustained teacher wellbeing is also linked to enhanced pedagogical efficacy, professional engagement, and the modelling of wellbeing for learners. This study examines how character strengths function as a scaffolding language through which wellbeing literacy, the intentional language to comprehend and compose wellbeing for self and others, is integrated within initial teacher education for pre-service teachers. Six podcast episodes from the Teachers Supporting Teachers series captured conversations between pre-service teachers and university academics exploring character strengths understanding and enactment. …
Governing Professional Mobility: An Llm-Assisted Framework And Empirical Taxonomy Of Health-Professional Mobility Agreements, David C. Benton, Andrew D. Benton
Governing Professional Mobility: An Llm-Assisted Framework And Empirical Taxonomy Of Health-Professional Mobility Agreements, David C. Benton, Andrew D. Benton
Research outputs 2022 to 2026
Background: Health-professional mobility agreements (eg, compacts, mutual recognition arrangements, memoranda of understanding) are increasingly used to address workforce shortages, support crossborder practice, and enable new technology-mediated modes of service delivery. Regulators need rapid, reproducible ways to assess whether such instruments protect the public while facilitating proportionate professional mobility.
Purpose: To develop and internally test a 10-dimension, 41-subdimension assessment framework for health-professional mobility agreements; examine whether large language model (LLM)–assisted coding can approximate expert legal regulatory assessment; and derive an empirical taxonomy of mobility and other similar instruments.
Methods: A focused documentary synthesis of legal instruments, academic literature, and intergovernmental guidance …
Hamstring Strength Assessment Methods In Sport: A Systematic Review And Meta-Analysis Of Post-Activity Strength Decrements, Asymmetry Benchmarks, And Measurement Reliability, Adam E. Sundh, Nicholas J. Ripley, A. J. Lamb, Paul Comfort
Hamstring Strength Assessment Methods In Sport: A Systematic Review And Meta-Analysis Of Post-Activity Strength Decrements, Asymmetry Benchmarks, And Measurement Reliability, Adam E. Sundh, Nicholas J. Ripley, A. J. Lamb, Paul Comfort
Research outputs 2022 to 2026
Hamstring strain injuries (HSI) represent one of the most prevalent and recurrent injuries in sport, making reliable strength assessment essential for neuromuscular monitoring in athletic populations. Despite the breadth of available testing modalities, no comprehensive synthesis of assessment methods, their reliability, post-activity strength responses, or normative asymmetry values has been undertaken. This systematic review and meta-analysis aims to evaluate the reliability of hamstring strength assessment methods, quantify the time-course of strength decrements following competition, establish normative inter-limb asymmetry benchmarks, and identify gaps to guide future assessment practices. PubMed, Scopus, SPORTDiscus, and Web of Science were searched from inception to November …
Human Resource Development Practices And Employee-Focused Voice: A Conceptual Model And Research Agenda, Hossein Ali Abadi, Andreas Wallo, Daniel Lundqvist, Alan Coetzer, Janice Redmond
Human Resource Development Practices And Employee-Focused Voice: A Conceptual Model And Research Agenda, Hossein Ali Abadi, Andreas Wallo, Daniel Lundqvist, Alan Coetzer, Janice Redmond
Research outputs 2022 to 2026
Critical theorists contend HRD has prioritized managerial interests over employee well-being. Some have advocated an ethics of care approach, emphasizing employee needs and well-being. However, there are few models to guide research on integrating care-oriented practices. We adopt a mutual gains perspective, proposing that HRD practices can enhance performance and employee well-being through employee-focused voice. HRD has overlooked voice, which is well-theorized in HRM. To address this gap, we conceptualize how key practices can foster employee-focused voice. We adapt and extend Nishii and Wright’s (2008) HR process model, integrate leadership styles, and develop propositions to guide studies on facilitating voice.
Information-Processing Gap And Insider Trading Profitability: Evidence From The Xbrl Mandate, Yuyun Huang, Jerry T. Parwada, Yuan George Shan, Joey W. Yang
Information-Processing Gap And Insider Trading Profitability: Evidence From The Xbrl Mandate, Yuyun Huang, Jerry T. Parwada, Yuan George Shan, Joey W. Yang
Research outputs 2022 to 2026
The information processing costs faced by external investors may provide corporate insiders with a comparative advantage. We examine how the phased introduction of the eXtensible Business Reporting Language (XBRL) mandate, designed to lower investors' costs of processing public disclosures, affects insiders’ trading profitability. We find that opportunistic insider sales, but not purchases, become significantly less profitable following the first wave of mandatory XBRL adoption. This decline is consistent with a reduced number of insider sales preceding 10-K filings that convey unfavorable news, as well as with a general fall in insider trading activity and profitability across all three mandate waves. …
Invertivore Fish Predation Is An Overlooked Source Of Carbonate Sediment On A Turbid Coral Reef, Jake L. Nilsen, Nicola K. Browne, Kyle M. Morgan, Joshua L. Bonesso, Dylan Benson, Shannon Dee, Michael J. O’Leary, Lisa A. Kirkendale, Peter U. Middelfart, Michael V.W. Cuttler, Jennifer L. Mcilwain
Invertivore Fish Predation Is An Overlooked Source Of Carbonate Sediment On A Turbid Coral Reef, Jake L. Nilsen, Nicola K. Browne, Kyle M. Morgan, Joshua L. Bonesso, Dylan Benson, Shannon Dee, Michael J. O’Leary, Lisa A. Kirkendale, Peter U. Middelfart, Michael V.W. Cuttler, Jennifer L. Mcilwain
Research outputs 2022 to 2026
The geomorphic stability of coral reef islands depends on a continued supply of biologically derived sediment from reefs. However, the ecological processes that produce detrital sediment remain poorly resolved. The role of fishes as sediment producers has largely focused on coral sand generated by parrotfishes (Labridae: Scarinae) in clear-water settings, while the contribution of other groups, such as durophagous invertivores, remains poorly understood. Here, we quantify the contribution of invertivores to carbonate sediments at an inshore reef in the Exmouth Gulf, Western Australia, by combining fish census data and dietary analysis, coupled with taphonomic and compositional analysis of benthic sediments. …
It Will Only Work If Everyone Is On Board: A Needs And Context Assessment To Inform Exercise Oncology Implementation Within A Public Healthcare Organisation, Georgia L. White, Mary A. Kennedy, Bryan A. Chan, Hattie Wright, Grace L. Rose
It Will Only Work If Everyone Is On Board: A Needs And Context Assessment To Inform Exercise Oncology Implementation Within A Public Healthcare Organisation, Georgia L. White, Mary A. Kennedy, Bryan A. Chan, Hattie Wright, Grace L. Rose
Research outputs 2022 to 2026
Introduction: Exercise has well-established benefits across the cancer continuum for people living with and beyond cancer, yet the exercise oncology field faces a research-to-practice gap. Understanding the factors that influence implementation in any given context is essential to ensure implementation strategies have the greatest likelihood of success. The study mapped onsite exercise oncology services, staff-reported implementation barriers and facilitators, organisational readiness, and experiences reported by people living with or beyond cancer, across a large public healthcare organisation.
Methods: Staff and people living with and beyond cancer across cancer care centres within the public healthcare organisation completed an online survey. Data …
Knowledge, Intentions And Attitudes Towards Osteoporosis And Other Health Conditions Among Older Australians, Phuong Dung Lam, Satvinder S. Dhaliwal, Christina M. Pollard, Jonine M. Jancey, Richard L. Prince, Deborah A. Kerr
Knowledge, Intentions And Attitudes Towards Osteoporosis And Other Health Conditions Among Older Australians, Phuong Dung Lam, Satvinder S. Dhaliwal, Christina M. Pollard, Jonine M. Jancey, Richard L. Prince, Deborah A. Kerr
Research outputs 2022 to 2026
Background: Osteoporosis burden is underdiagnosed and undertreated. While increasing community awareness and education are recognised priorities, research on how older adults view osteoporosis is limited. The aim was to assess osteoporosis-related knowledge, intentions and attitudes in relation to other health conditions in Australian adults aged 50 years and older.
Methods: A validated online questionnaire, developed with an expert panel, was administered to 1432 healthy volunteers, (64.3 ± 9.5 years). The questionnaire assessed knowledge of osteoporosis risk factors, attitudes and intentions. Multivariable logistic regression identified factors associated with low knowledge.
Results: Knowledge score across six topics was 29.5 ± 14.5 (100 …
Load-Settlement Behaviour Of Tailings Dam Foundation Strengthened Using The Wraparound Geosynthetic Reinforcement Technique, Francis Otieno, Sanjay Kumar Shukla
Load-Settlement Behaviour Of Tailings Dam Foundation Strengthened Using The Wraparound Geosynthetic Reinforcement Technique, Francis Otieno, Sanjay Kumar Shukla
Research outputs 2022 to 2026
This paper presents a numerical investigation of the load–settlement behaviour of a geosynthetic-reinforced tailings foundation comprised of gold tailings, subjected to the weight of a tailings dam embankment. The study considered varying conditions, including the horizontal and vertical components of the wraparound reinforcement, reinforcement burial depth, and shear strength parameters of the foundation material. A particular focus of this study is to investigate the effect of reinforcement wraparound ends on the settlement behaviour of the foundation using commercially available finite element (FE) software. The reinforcement is a single-layer biaxial woven geotextile, with and without wraparound ends, at varying depths from …
Mental Health Impacts Of Anti-Trans Stigma On Transgender People In Australia: A Mixed-Methods Study, Sav Zwickl, Sasha Bailey, Rin Chan, Shalem Y. Leemaqz, Joel Murray, Stevie Lane, Foster Skewis, Julian Grace, Eli Ward-Smith, Tomi Ruggles, Ada S. Cheung
Mental Health Impacts Of Anti-Trans Stigma On Transgender People In Australia: A Mixed-Methods Study, Sav Zwickl, Sasha Bailey, Rin Chan, Shalem Y. Leemaqz, Joel Murray, Stevie Lane, Foster Skewis, Julian Grace, Eli Ward-Smith, Tomi Ruggles, Ada S. Cheung
Research outputs 2022 to 2026
Background: Anti-trans stigma has escalated globally, yet there is limited empirical evidence examining its mental health impacts on trans populations.
Methods: In a May 2024 mixed-methods cross-sectional online survey, trans people aged ≥16 years living in Australia reported the frequency of seven anti-trans stigma experiences in the previous month, including exposure to anti-trans remarks in the news media or online; personal experience of online bullying, harassment or threats; having thought about, seen or heard about anti-trans rhetoric by Australian politicians and high-profile individuals; or anti-trans rallies; or police violence; or international anti-trans legislation and violence. Generalized linear models examined associations …
Pain In People With Dementia Is A Significant Contributor To Increased Professional Caregiver Burden: Results Of An Observation Study, Kreshnik Hoti, Ipsit Vahia, Paola Chivers, Jeffery Hughes
Pain In People With Dementia Is A Significant Contributor To Increased Professional Caregiver Burden: Results Of An Observation Study, Kreshnik Hoti, Ipsit Vahia, Paola Chivers, Jeffery Hughes
Research outputs 2022 to 2026
Aim: To investigate the association between the presence of neuropsychological symptoms, professional caregiver burden and pain intensity.
Methods: Eleven neuropsychiatric symptoms reportedly associated with caregiver burden which are included within the PainChek® pain assessment tool were identified: aggressiveness, inappropriate behavior, distressed, verbally offensive, confusion, restlessness, pacing and wandering, crying, screaming, altered sleep and resisting care. A caregiver burden score based on binary scoring of the presence of these indicators was calculated (summative score range from 0 to 11). Generalized estimating equations were used to evaluate the relationships between (1) pain score and sum of caregiver indicators present and (2) pain …
Relationships Between Physical Performance Characteristics And Match Characteristics Of English Academy Soccer Players, B. Dickinson, P. Jones, P. Comfort
Relationships Between Physical Performance Characteristics And Match Characteristics Of English Academy Soccer Players, B. Dickinson, P. Jones, P. Comfort
Research outputs 2022 to 2026
The aim of this study was to determine the relationships between physical performance and match characteristics of Elite academy soccer players using pooled data across U15, U16, U18, U23 age groups. Sixty elite academy soccer players including u15 (Subject: N = 15; age: 14.64 ± 0.25; mass: 59.88 ± 9.12 kg; height: 171 ± 6.69 cm), u16 (Subject: N = 15; age: 15.42 ± 0.36; mass: 65.11 ± 8.70 kg; height: 175 ± 7.21 cm), u18 (Subject: N = 15; age: 17.00 ± 1.00; mass: 72.85 ± 7.43 kg; height: 179 ± 6.43 cm), u23 (Subject: N = 15; age: …
School Is No Longer A Lone Wolf Effort: Leadership Strategies For Inclusive, Community-Based School Cultures, Stuart Woodcock, Elias Avramidis, Umesh Sharma, Pearl Subban, Caroline Sahli Lozano, Harry Kullman, Tim Lorman, Sergej Wüthrich, Margarita Knickenberg
School Is No Longer A Lone Wolf Effort: Leadership Strategies For Inclusive, Community-Based School Cultures, Stuart Woodcock, Elias Avramidis, Umesh Sharma, Pearl Subban, Caroline Sahli Lozano, Harry Kullman, Tim Lorman, Sergej Wüthrich, Margarita Knickenberg
Research outputs 2022 to 2026
Based on the premise that the successful implementation of inclusion is largely dependent on the educators’ commitment to inclusive ideals, this study sought to examine the ways principals promote an inclusive vision and foster the development of associated practices in their school community. The study employed an exploratory qualitative research design, collecting data through semi-structured interviews and focus groups with 12 principals of highly-ranked inclusive schools from four countries: Australia, Italy, Switzerland, and Spain. In so doing, the emphasis was placed on the principals’ perspectives and practices that contribute to the development of an inclusive school culture. The iterative process …
The Evolution Of Match-Play In Major League Soccer From 2018 To 2023, Callum J. Mccaskie, Christopher Wing
The Evolution Of Match-Play In Major League Soccer From 2018 To 2023, Callum J. Mccaskie, Christopher Wing
Research outputs 2022 to 2026
Major League Soccer (MLS) has experienced significant growth since its establishment 30 years ago. However, no research has investigated the on-field performance trends. Thus, the purpose of this study was to examine the evolution of MLS match-play via technical and tactical key performance indicators, and investigate the differences between teams according to league finishing position. MLS on-field performance indicators were obtained across six seasons from open-source website FBref. Mean game values were collected from 21 match performance indicators for every MLS team over six seasons. Teams were also classified according to their league finishing position at the conclusion of each …
Towards The Acoustic Characterisation Of Ngilgi Cave's Amphitheatre Chamber In Western Australia, Mary Rapp, Manuj Yadav, John Bassett
Towards The Acoustic Characterisation Of Ngilgi Cave's Amphitheatre Chamber In Western Australia, Mary Rapp, Manuj Yadav, John Bassett
Research outputs 2022 to 2026
Ngilgi Cave, Western Australia’s first show cave and a site of Wardandi custodianship for tens of thousands of years, has long been celebrated for its “remarkable acoustics”. This reputation is anchored in the early twentieth-century anecdote of Dame Nellie Melba singing in its Amphitheatre chamber. This paper presents a quantitative acoustic characterisation of that chamber using in situ measurements within a nominal 2500 m3 interconnected limestone volume with dense speleothem surfaces. Room acoustic parameters were measured as per ISO 3382–1 across four receiver positions spanning 1–15 m from the source. Spatially-averaged mid-frequency Reverberation Time was 1.2 s, Early Decay Time …
When Does The Peak Countermovement Jump Performance Occur? Mapping Peak-Trial Timing Across Six Clustered Repetitions, Karol Kruczek, Szymon Karpęcki, Tim Gabbett, Jason Lake, Michał Nowak
When Does The Peak Countermovement Jump Performance Occur? Mapping Peak-Trial Timing Across Six Clustered Repetitions, Karol Kruczek, Szymon Karpęcki, Tim Gabbett, Jason Lake, Michał Nowak
Research outputs 2022 to 2026
Force-plate countermovement jump (CMJ) testing is widely used to assess neuromuscular status, yet monitoring interpretation often relies on best-trial values from abbreviated protocols, potentially biasing conclusions when the session maximum occurs beyond the sampled attempts. We mapped peak-trial timing across a six-trial clustered (3 + 3) CMJ protocol for seven outcome and strategy force–time metrics, and tested whether this peak-trial pattern was preserved between personal best (PB) and typical state (TS) monitoring sessions, both defined using modified reactive strength index (mRSI) as the primary selection variable. Retrospective dual-force-plate data (1000 Hz; August 2020–December 2025) were analysed from 314 athletes who …
When The Panic Sets In: Ai-Proofing As Pedagogical Violence In Social Work Education, Norah Hosken, Susan Bailey
When The Panic Sets In: Ai-Proofing As Pedagogical Violence In Social Work Education, Norah Hosken, Susan Bailey
Research outputs 2022 to 2026
Universities’ rushed responses to generative Artificial Intelligence (AI) constitute pedagogical violence against students and educators in social work programs. Drawing on Matusov and Sullivan’s pedagogical violence framework and Bourdieu’s symbolic violence, we examine how institutional mandates to ‘AI-proof’ assessments contradict core social work values while inflicting systematic harm. AI-proofing policies impose time-limited assessments disadvantaging disabled students and those with caring responsibilities, deploy surveillance technologies that discriminate against non-native English speakers, demand unsustainable workload increases from burned-out educators, and dismantle scaffolded pedagogy aligned with how social workers learn to practise. Using collaborative autoethnography, we document our experiences across Australian universities and …
Multi-Omics Integration Reveals Vaccine-Specific Molecular Signatures And Temporal Dynamics Of Covid-19 Immune Responses, Anne H. Klein, David J. Beale, Thao V. Nquyen, Jian-Wei Liu, Petrus Jansen Van Vuren, Nagendrakumar B. Singanallur, Carol Lee, Andrew C. Boomer, Jennifer A. Juno, Stephen J. Kent, Adam K. Wheatley, Gough G. Au, Seshadri S. Vasan, Laurence Wilson, Alexander J. Mcauley
Multi-Omics Integration Reveals Vaccine-Specific Molecular Signatures And Temporal Dynamics Of Covid-19 Immune Responses, Anne H. Klein, David J. Beale, Thao V. Nquyen, Jian-Wei Liu, Petrus Jansen Van Vuren, Nagendrakumar B. Singanallur, Carol Lee, Andrew C. Boomer, Jennifer A. Juno, Stephen J. Kent, Adam K. Wheatley, Gough G. Au, Seshadri S. Vasan, Laurence Wilson, Alexander J. Mcauley
Research outputs 2022 to 2026
Vaccination elicits systemic immune responses that extend beyond antibody and lymphocyte activation, engaging coordinated metabolic and lipid pathways that modulate immune function. Nevertheless, how systemic molecular responses differ across COVID-19 vaccine platforms, including closely related mRNA platforms, remains poorly understood. Here, we performed integrated plasma proteomic, lipidomic, and metabolomic profiling of 53 SARS-CoV-2–naïve adults vaccinated with Pfizer-BioNTech, Moderna, or AstraZeneca COVID-19 vaccines. Samples were analysed across multiple timepoints using differential analysis and DIABLO-based multi-omics integration. Our findings reveal distinct platform-associated multi-omic molecular signatures not captured by unsupervised analyses alone. Pfizer-BioNTech vaccination was associated with widespread increases in immunoglobulin and complement …
Co-Designing Impact: Student-Led Prevention Messaging For The Primary Prevention Of Violence Against Women, Narelle Lemon, Lisa Holmes, Christina C. Gray, Jason Goopy
Co-Designing Impact: Student-Led Prevention Messaging For The Primary Prevention Of Violence Against Women, Narelle Lemon, Lisa Holmes, Christina C. Gray, Jason Goopy
Research outputs 2022 to 2026
Executive Summary:
Violence against women remains one of Western Australia's most serious and persistent social problems, and young adults aged 18–24 represent a pivotal demographic for primary prevention — the work of stopping violence before it starts. The Co-Designing Impact project, funded by the Department of Communities' Family and Domestic Violence Primary Prevention Grants Program 2024/2026 and delivered in partnership between Yourtoolkit.com and Edith Cowan University (ECU), engaged university students aged 18–24 in a six-session co-design program. Participants learned about the drivers of violence against women and the principles of primary prevention, then co-designed social media messaging intended to shift …