Digital Commons Network^™

The Shared Superintendent In Iowa: Benefits, Challenges, And Lessons Learned Over The Last Thirty Years, Amanda Schmidt

Dissertations and Theses @ UNI

This study examined the benefits, challenges, and leadership qualities associated with the shared superintendent model, and compared them with lessons learned over the last thirty years. Understanding how this model impacts dynamics within schools and the community is crucial to identifying strategies that support effective governance and enhance educational outcomes for all involved. A qualitative, phenomenological study approach was used to research the role of the shared superintendent in rural Iowa. Participants were those who served as a shared superintendent between a minimum of two school districts within the state of Iowa and have held this position for at least …

Stem Identities Of Iowa State University's Biological And Biomanufacturing Systems Technology Students, Levi Nettleton

Dissertations and Theses @ UNI

No abstract provided.

From The Goodness Of Our Hearts: A Scoping Review Of Qualitative Literature On Altruism As A Reward Mechanism For Nursing, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Emily Horner, Norah L. Johnson

College of Nursing Faculty Research and Publications

Introduction

Altruism, the desire to help others, is a common motivation for choosing a career in nursing. Improved understanding of the role of altruism as a reward or motivation for currently-practicing nurses may inform future interventions to improve effort-reward balance among practicing nurses. Therefore, the purpose of this study was to collect, examine, and present literature on how altruism has been described as a reward mechanism or motivation for engaging in professional nursing.

Methods

This scoping review of literature used the Arksey & O’Malley method, PRISMA-ScR reporting checklist, and Rayyan review management platform. PubMed, Web of Science, and CINAHL were …

Organizing And Advocacy Analysis And Innovation, Shari Simon

Open Educational Resources

This assignment emphasizes students’ evaluation and creation skills while connecting to their broader coursework on advocacy and community engagement. Students analyze a real-world advocacy campaign, applying a SWOT framework to evaluate its strengths, weaknesses, opportunities, and threats. They then generate at least two original ideas to enhance or expand the campaign’s impact, drawing on their lived experiences, critical thinking, and social awareness. The assignment encourages the use of AI tools, such as ChatGPT, to support brainstorming, research, and content generation, with reflection on how AI contributed to their process. By integrating personal perspective, analytical rigor, and creative problem-solving, students develop …

Colloquial Language, Standard Language, Or Educated Language?, Rocio Carranza Brito

Open Educational Resources

This assignment invites students to critically explore Spanish dialects, regional expressions, and language variations through guided interactions with ChatGPT. Students will examine colloquialisms across chosen Spanish dialects, analyze their meanings and linguistic significance, and compare AI-generated examples with their own academic revisions. Through structured reflection, students will assess the strengths, limitations, and risks of using AI as a language tool. The focus will be on intentional prompting, linguistic awareness, and critical evaluation, rather than simply substituting human expression.

Analyzing Headers With Chatgpt, Raymond Rosas

Open Educational Resources

This assignment invites students to examine how section headers function as rhetorical and organizational tools in research writing by analyzing headers generated by ChatGPT. Using a shared sample text, students prompt generative AI to produce multiple sets of headers that foreground different analytical emphases (e.g., race or language). Students then compare these AI-generated headers to identify how shifts in emphasis reshape the implied structure, focus, and interpretation of a text. Through analysis and reflection, students use these insights to inform their own planning for inquiry-based research writing, while critically evaluating the affordances and limitations of generative AI at an early …

A Low-Stakes Assignment That Introduces Ai Technology Into The Analysis And Writing Process, Tim Mccormack

Open Educational Resources

In this ENG 225 assignment, students use AI (ChatGPT) to perform tasks related to summarizing, paraphrasing, quoting, and responding to a text, then compare the AI-generated work to their own. Using Blitzer’s article “The Rhetorical Situation”, students create APA citations, summaries, paraphrases, key quotes, and personal responses with AI guidance. The assignment emphasizes critical evaluation by having students analyze the accuracy, effectiveness, and differences between human and AI-generated work. This exercise develops skills in rhetorical analysis, source engagement, and reflective assessment of AI as a tool for writing and research.

Genocide, Memory & Prevention: Ethical Inquiry And Critical Thinking Through Research & Ai, Linda Humes

Open Educational Resources

This assignment engages students in ethical inquiry and critical analysis by examining lesser-known or silenced genocides within a global and historical context. Using academic sources alongside responsible use of generative AI, students compare dominant and marginalized narratives, analyze recurring patterns and causes of genocide, and reflect on prevention strategies. The assignment emphasizes ethical AI use, historical memory, and the development of civic awareness, empathy, and critical thinking in the study of race, power, and inequality.

Analyzing Best Practices In Reintegration, Education, Restorative Justice, And Reentry, Sergio Grossi

Open Educational Resources

This collaborative assignment in SOC 301 (Penology) requires students to critically examine best practices in reintegration, prison education, rehabilitation, and restorative justice through comparative international case studies, such as APAC, Bastøy Prison, or the Inside-Out Prison Exchange Program. Working in groups, students analyze at least five peer-reviewed sources to assess both documented benefits (e.g., reduced recidivism, improved reintegration) and key challenges (e.g., scalability and sustainability). The scaffolded structure—proposal, draft, final paper, and presentation—strengthens research skills, critical thinking, and evidence-based academic communication.

Analyzing The Use Of Ai To Transcribe An Interview In Spanish, Rocío Carranza Brito

Open Educational Resources

This assignment explores the differences between oral and written language and the challenges of transcribing speech. Students conduct an interview with a selected person, using ChatGPT to create and refine interview questions. They record the interview and use Otter.ai to generate a literal transcription that captures natural speech features such as repetitions and hesitations. After reviewing and correcting the transcript against the audio, students format it with participants’ initials to focus on content rather than timestamps. A simplified transcription guideline is applied to mark key elements. Finally, students reflect on the transcription process, addressing what was most difficult to represent …

Analyzing Minnick V. California Using Chatgpt, Nicholas Malkov

Open Educational Resources

This assignment in the Race and Ethnicity course asks students to critically analyze the Supreme Court case Wayne Minnick et al. v. California Department of Corrections et al. through a structured case brief and ethical use of AI. Students examine key legal elements of the case while exploring issues of race, ethnicity, and institutional discrimination in the correctional system. After briefing the case, students use AI tools to generate and revise discussion questions that deepen analysis of themes such as racial discrimination, intersectionality, sentencing, advocacy, and policy reform. The assignment emphasizes critical thinking, legal analysis, and responsible AI engagement.

Essay Assignment On Current Political Development, Esther Verhalle

Open Educational Resources

This assignment asks students to reflect on how recent election results may influence policies related to the administration of justice. Students use ChatGPT as a brainstorming tool to generate possible policy impacts, then select one example and analyze it using course readings. By connecting AI-generated ideas to established scholarly arguments, students practice evidence-based reasoning and application of course concepts. The assignment also requires students to reflect on the strengths and limitations of using AI for idea generation, emphasizing independent analysis, proper citation, and critical engagement with AI-assisted work.

Formulating Research Question With Chat Gpt, Nicholas Malkov

Open Educational Resources

This assignment guides students through the process of developing strong, focused, and measurable research questions while critically engaging with ChatGPT as a collaborative tool. Students begin by identifying a broad topic, narrowing it to a specific and feasible area of inquiry, and determining the purpose and type of research question (descriptive, explanatory, comparative, or evaluative). After drafting their own question, they use ChatGPT to generate feedback and suggested refinements, which they must evaluate critically using the FINER criteria (Feasible, Interesting, Novel, Ethical, Relevant). Through comparison of AI-generated and human-generated revisions, students assess the strengths, limitations, and ethical considerations of AI …

Digital Cultures, Dei, And Ai: Critical Analysis Assignment, Oluremi Alapo

Open Educational Resources

This assignment presents a scaffolded, equity-centered approach to teaching digital culture and artificial intelligence (AI) within an undergraduate Diversity and Multicultural Education course at the City University of New York. Designed as a Writing Intensive, COIL-informed learning experience, the assignment invites students to critically examine digital technologies and AI as social and cultural systems shaped by power, access, and inequality.

Pharmacogenetic Hslco1b1*14-Guided Dosing Of Methotrexate In Transgenic Arthritic Mice Normalizes Exposure And Response., Felicia Gooden, Brennan D. Meier, Griffin D. Shaffer, Kim Gibson, Paul Toren, Nieko C. Punt, Sandhya Subash, Dilip K. Singh, Bhagwat Prasad, Laura Ramsey, Zachary L. Taylor

Manuscripts, Articles, Book Chapters and Other Papers

Juvenile idiopathic arthritis (JIA) is a chronic autoimmune disease that negatively affects ~100,000 children under the age of 16 in the United States. About ~30% of these patients fail first-line drug therapy with low-dose methotrexate (MTX) due to poor tolerability or lack of efficacy. The SLCO1B1*14 allele is associated with increased MTX clearance and has been linked to reduced overall drug exposure and nonresponse to MTX in JIA patients. Herein, we describe transgenic hSLCO1B1*14 and hSLCO1B1*1 DBA1/J mSlco1b2 knock-out mice, which we used to assess arthritic response to MTX using the collagen-induced arthritis model. Mass spectrometry-based proteomics analysis revealed that …

Constitutional Powers Midterm Exam, Jordan Reitzfeld

Open Educational Resources

Students apply constitutional principles and court decisions to contemporary questions about the powers of Congress, the president, and the judiciary. They defend positions on possible reforms and analyze property rights, copyright, and trademark issues.

Reimagining Justice: Transformative Justice Analysis In Adult Felony Cases, Marisa Tramontano

Open Educational Resources

In this sociology final project, students take the role of a sociologist working with a public defender and analyze the records and social history of a client facing sentencing for a felony. They write a report for a judge explaining how structural factors and sociological concepts illuminate the case, then recommend responses that include alternatives to incarceration. A reflective essay examines the limits of the available information, ethical considerations, and how the project shaped their understanding of justice.

The Trials We Remember: Exploring Historical Significance Through Interviews, Sara Mcdougall

Open Educational Resources

Students interview someone about a judicial trial that mattered to them and reflect on a trial of personal significance. They share what they learned through a classmate presentation, exploring how people assign meaning to trials while practicing communication skills.

(Re)Discovering The Streets Of Nyc: Honorary Signs, Sticker Street Art & Collective/Collaborative Investigations, Mark Mcbeth

Open Educational Resources

In a scaffolded series of assignments, students investigate NYC honorary street signs and sticker art through photography, research, individual essays, and a collaborative project.

The Steelerville Case: Applying Criminological Theory To Crime And Police Morale, Shamus Smith

Open Educational Resources

Students use a fictional town’s economic decline and rising crime to evaluate at least two criminological theories and their implications for policy. Role-playing as consultants, they develop research-supported recommendations to reduce crime and improve police morale.

Association Of N-Terminal Pro-Brain Natriuretic Peptide With Ckd Progression In The Ckd In Children Study., Alexander Kula, David K. Prince, Joseph T. Flynn, Susan L. Furth, Bradley A. Warady, Tamara Isakova, Derek Ng, Jeese Seegmiller, Rob Christenson, Nisha Bansal

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Expanding The Genetic And Phenotypic Spectrum Of Polrmt-Related Mitochondrial Disease., Mahmoud R. Fassad, Sebastian Valenzuela, Monika Oláhová, Jack J. Collier, Charlotte V Y Knowles, Eleni Mavraki, Miriam Elbracht, Nergis Güzel, Thomas Herberhold, Ingo Kurth, Andrea Maier, Larissa Mattern, Carol J. Saunders, Helen Mccullagh, Katrin Õunap, Saskia B. Wortmann, Andre Reis, Lei Zhang, Claes M. Gustafsson, Robert Mcfarland, Robert W. Taylor

Manuscripts, Articles, Book Chapters and Other Papers

Mitochondrial diseases are a complex group of conditions exhibiting significant phenotypic and genetic heterogeneity. Genomic testing is increasingly used as the first step in the diagnostic pathway for mitochondrial diseases. We used next-generation sequencing followed by bioinformatic data analysis to identify potentially damaging variants in the POLRMT gene (NM_005035.4) in six new affected individuals. Structural protein analysis predicted the detrimental impact of variants on POLRMT protein structure. Patients show extended phenotypic abnormalities often presenting early in life with features including global developmental delay, cognitive impairment, short stature and muscular hypotonia. This study expands the genetic and phenotypic landscape of mitochondrial …

Greater Body Dissatisfaction At Admission Is Associated With Lower Bmi At Discharge In Anorexia Nervosa: Predictive Validity Of The Eating Pathology Symptoms Inventory., Danielle A N Chapa, Marianna L. Thomeczek, Brianne N. Richson, Alan Duffy, Kara A. Christensen Pacella, Kelsie T. Forbush, Renee D. Rienecke, Dan V. Blalock, Sara R. Gould, Victoria L. Perko, Philip S. Mehler

Manuscripts, Articles, Book Chapters and Other Papers

People with anorexia nervosa (AN) engage in dietary restriction and other weight loss behaviors that result in dangerously low body weight, leading to an increased risk for mortality and medical complications. Weight gain is one of the most important indicators of treatment progress and recovery for AN. There are limited predictors of weight gain for patients with AN, making it difficult for clinicians to anticipate which patients are likely to respond favorably to treatment. Thus, there is a need to identify additional, potentially modifiable predictors of weight gain within a higher level of care for AN. This study tested the …

A Comparison Of Poly(Methyl Methacrylate) And Silorane-Based Cements As Carriers For Local Doxorubicin Delivery., Grahmm A. Funk, Elizabeth M. Menuey, Zachary D. Denton, Dalan M. Pittz, Alejandro Parrales, Tomoo Iwakuma, Kathleen V. Kilway, Terence E. Mciff

Manuscripts, Articles, Book Chapters and Other Papers

Orthopedic osteosarcomas and metastatic lesions can be difficult to treat with systemically delivered chemotherapy agents alone. Following removal of the primary tumor, implantation of cement to fill the lesion is often done to stabilize weight-bearing bones. One of the commonly used treatments to address osteosarcoma is systemic delivery of doxorubicin. Therefore, research on the incorporation and release of efficacious doxorubicin for local delivery from cement is important. Poly(methyl methacrylate) (PMMA)-based bone cements are the gold standard in orthopedics but have inherent disadvantages. Efforts to overcome some of these deficiencies led to the development of a novel silorane-based biomaterial (SBB). This …

Bovine Lactoferrin Maintains Antibacterial Effect Against Neonatal Escherichia Coli Septicaemia Isolates Despite The Presence Of Iron Acquisition Genes, Matthew Mayorga, Joshua Wheatley, Brianna N. Maldonado, Susana Chavez-Bueno

Manuscripts, Articles, Book Chapters and Other Papers

Introduction. Escherichia coli is a dominant cause of neonatal sepsis for which no prevention measures currently exist. Lactoferrin (LF) is an iron-sequestering antibacterial protein that has been noticed to decrease neonatal late-onset sepsis.Hypothesis/Gap Statement. LF's effect on in vitro growth of neonatal E. coli clinical isolates causing septicaemia is unknown. The prevalence of iron acquisition virulence genes which contribute to pathogenicity outcomes in these strains has also not been described in detail.Aim. To evaluate bovine lactoferrin's (bLF) effects on the in vitro growth of neonatal septicaemia E. coli isolates, and to determine the presence of iron acquisition virulence …

Identification Of Neural Crest And Melanoma Cancer Cell Invasion And Migration Genes Using High-Throughput Screening And Deep Attention Networks., J C Kasemeier-Kulesa, S Martina Perez, R E Baker, Paul M. Kulesa

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Cell migration and invasion are well-coordinated in development and disease but remain poorly understood. We previously showed that the neural crest (NC) cell migratory wavefront shares a 45-gene panel with other cell invasion phenomena. To rapidly and systematically identify critical genes, we performed a high-throughput siRNA screen and statistical and deep learning analyses to determine changes in NC- versus non-NC-derived human cell line behaviors.

RESULTS: We find 14 out of 45 genes significantly reduced c8161 melanoma cell migration; four of the 14 genes altered leader cell motility (BMP4, ITGB1, KCNE3, and RASGRP1). Deep learning identified marked disruptions in cell-neighbor …

Safety And Effectiveness Of Emicizumab In People With Haemophilia A Enrolled In The Athn 7 Haemophilia Natural History Study., Tyler W. Buckner, Shannon L. Carpenter, Nabil Daoud, Christine L. Kempton, Lucy Lee, Lynn Malec, Thomas W. Mclean, Paul Morton, Carrie O'Neill, Janice M. Staber, Michael Wang, Stacy E. Croteau, Michael Recht

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: The Natural History Study of the Safety, Effectiveness, and Practice of Treatment for People with Haemophilia (ATHN 7) monitors use of contemporary haemophilia therapies, including emicizumab, a bispecific antibody substituting for activated factor (F)VIII in people with haemophilia A (HA).

AIM: To report participant characteristics and real-world safety and effectiveness of emicizumab in ATHN 7.

METHODS: ATHN 7 is a prospective observational cohort study conducted across 26 American Thrombosis and Haemostasis Network (ATHN)-affiliated sites. People with HA receiving emicizumab were eligible for inclusion in this analysis. Clinical information was collected quarterly through participant interview and medical record review. Safety …

A 20th Century Historical Perspective On Congenital Syphilis And Lessons For Today., Jane F. Knapp, Robert Schremmer

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Evaluation Of Mycoplasma Genitalium Positivity And Co-Infection With Chlamydia Trachomatis And/Or Neisseria Gonorrhoeae At Various Care Sites Across The United States, Rebecca Lillis, Rodney Arcenas, Christy M. Boraas, Steven E. Chavoustie, Lashonda Crane, Nicole D'Empaire, Aaron C. Ermel, Glenn Harnett, Federico Hinestrosa, Stacey House, Joseph Miller, Anthony Mills, Ronald Poblete, Stephen Young, Barbara Van Der Pol

School of Medicine Faculty Publications

OBJECTIVES: We evaluated Mycoplasma genitalium (MG) positivity and co-infection with Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG), based on results from a trial assessing clinical performance of the Cobas® Liat CT/NG/MG point-of-care test. METHODS: A prospective, US, multicenter, noninterventional study assessed MG positivity in prospective urine samples (male) and clinician-collected vaginal swabs (female) from symptomatic/asymptomatic patients aged ≥14 years attending various clinical settings. Participants were designated positive or negative for MG, CT, and NG based on combined results from three US Food and Drug Administration-approved assays and one laboratory-developed test. MG co-infection with CT and/or NG was assessed. RESULTS: Among …

Optimizing Healthy Aging: A Preventative Approach To Support Community-Dwelling Older Adults, Jada Welke

Occupational Therapy Capstones

Introduction: Healthy aging is a complex and multidimensional process influenced by physical, cognitive, psychosocial, environmental, and lifestyle factors across the lifespan. Increasing evidence from researchers suggests that many health care systems continue to rely on reactive models that address decline only after functional limitations emerge. Preventive interventions initiated in midlife have the potential to significantly influence long-term health outcomes, independence, well-being, and quality of life. As a result, there is growing recognition that multidimensional, proactive screening and intervention should begin earlier, before age-related conditions become clinically significant.

Purpose: The purpose of this scholarly project was to address this need through …