Digital Commons Network^™

Quantifying Nurse And Midwife-Led Research Impact: Retrospective Application Of The Framework To Assess The Impact From Translational Health Research (Fait) Model On Two Exemplar Randomised Controlled Trials, Kim Neylon, Rouen, Lisa Whitehead, Greg Sharplin, Kathleen Baird, Marion Eckert

Research outputs 2022 to 2026

Background: Nurse- and midwife-led clinical trials are underrepresented in Australia and New Zealand, despite their potential to improve health outcomes and deliver economic value. Demonstrating the broader impact of such research is essential to inform policy and funding decisions. Aim: To assess the utility of the Framework to Assess the Impact from Translational health research (FAIT) in capturing the translational impact of nurse- and midwife-led randomised controlled trials through retrospective application to two exemplar studies. Methods: FAIT was retrospectively applied to the RSVP (nurse-led) and DAME (midwife-led) trials using three components: Modified Payback, Economic Analysis, and Narrative. Program Logic Models …

S-Methyl Cysteine Sulfoxide: Its Effects On Cardiometabolic Outcomes In High-Fat Fed C57bl/6 Mice And Relevance To Human Health, Caroline R. Hill, Balmer, Hayley Abbiss, Jonathan M. Hodgson, Joshua R. Lewis, Armaghan Shafaei, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

S-Methyl cysteine sulfoxide (SMCSO) is an organosulfur compound with demonstrated hypocholesterolemic, anti-diabetic, and antioxidant benefits in rodents. However, the doses used have limited translatability for humans. We explored whether SMCSO could blunt development of diet-induced metabolic syndrome features in mice using doses that are potentially more translatable and achievable in humans. Male mice (C57BL/6; n = 54) were randomly assigned into one of five groups: [1] normal-diet; [2] high-fat-diet; or high-fat-diet with [3] 60 mg kg⁻¹, [4] 170 mg kg⁻¹, or [5] 350 mg per kg per body weight (BW) of SMCSO, respectively. Doses were administered …

On Burden Of Diseases, Prevention, Medical Research And Health Service Delivery: Grampian Case Study, Seshadri S. Vasan, Sudarshan Anand, Miae Lee, Nicholas C. Fluck

Research outputs 2022 to 2026

Burden of diseases measured as disability-adjusted life years (DALYs) per 100,000 people can be mined from public domain data, when they are made available by population health surveillance systems. This can be analysed to allow insightful comparisons with the national average, and to understand differences in trends between the sexes, age groups, time periods, geographic regions, and sub-regions. In this illustrative case study, we have analysed the Scottish burden of disease database to understand what ailed the population of the Grampian region before the COVID-19 pandemic. We have identified that selected cancers, ischaemic heart disease, Alzheimer’s disease and other dementias …

A Randomized Double-Blind, Placebo-Controlled Dose–Response Study To Assess The Gluten Threshold Dose In Celiac Disease, A. James M. Daveson, Emma Craig, Alina Vitak, Robert S. Ware, Jennifer Schafer, Anuj Sehgal, Utpal Bose, Michelle J. Colgrave, Melinda Y. Hardy, Jason A. Tye-Din, Robert P. Anderson

Research outputs 2022 to 2026

Background & Aims: Celiac disease is an immune-mediated enteropathy triggered by gluten ingestion. The effect of very small gluten exposures remains uncertain, contributing to international variations in food-labeling standards. Interleukin 2 (IL2) rises rapidly after gluten ingestion, serving as a biomarker of immune activation. We aimed to identify the lowest gluten dose that elicits a measurable IL2 response and accompanying symptoms in treated celiac disease. Methods: We conducted a randomized double-blind, placebo-controlled adaptive dose–response trial in adults with biopsy-proven celiac disease on a gluten-free diet for >2 years. Participants (n = 51; median age, 52 years; 69% were female) underwent …

Beyond Assumptions: What Students Really Think About School Wellbeing Programs, Amanda Madden

Research outputs 2022 to 2026

The study examined students’ perceptions of effective components in school-based wellbeing programs, addressing a critical gap where adolescent voices are absent. Data was gathered through a questionnaire, individual interviews, and focus groups conducted with 36 Year 12 students across three independent co-educational schools in Western Australia. Thematic analysis identified seven key components essential for effective wellbeing programming: targeted content providing respite from academic pressures, engaging and relatable presenters, strategic timing, developmental appropriateness, meaningful measurement, genuine teacher engagement, and authentic incorporation of student voice. Students valued practical, non-academic content and expressed scepticisms about teacher-delivered programs. Timing emerged as a previously underexplored …

Global, Regional, And National Burden Of Epilepsy, 1990–2021: A Global Burden Of Disease Study, Jinqing Zhao, Qiannan Chen, Jiahan Dong, Meng Gao, Siqi Ge, Anxin Wang

Research outputs 2022 to 2026

Background: Epilepsy is a common neurological disorder characterised by spontaneous seizures without an identifiable cause, leading to high morbidity and a significant public health burden. Understanding trends in its incidence, prevalence, mortality, and disability-adjusted life years (DALYs) is essential for developing effective prevention and treatment strategies. We aim to describe global trends in epilepsy over the past 32 years and explore the impact of sociodemographic index (SDI) levels on disease burden using the Global Burden of Disease 2021 data. Methods: We analysed the global burden of epilepsy (1990–2019) using age-standardised rates (ASRs) and their 95% uncertainty intervals (UI). We assessed …

Gender Justice In The Triple Planetary Crisis: A Scoping Review, Catelyn Richards, Micah Peters, Julia Charalambous, Lila Singh-Peterson, Lucy Osborn, Aletha Ward, Jessica Leclair, Tracy Levett-Jones

Research outputs 2022 to 2026

Aim: To identify and report how gender justice is conceptualised and discussed in contemporary health literature in relation to the Triple Planetary Crisis of climate change, pollution and biodiversity loss, with a particular focus on the experiences of women and gender-diverse populations, and the representation of nurses and other healthcare professionals dominated by women. Design: Scoping review. Data Sources: Searches were conducted across MEDLINE (Ovid), Scopus, CINHAL, Embase and ProQuest, focusing on studies published from January 1 2000–23 September 2024. Review Methods: The review was conducted in accordance with the JBI methodology for scoping reviews and reported against the Preferred …

Methodological Considerations For Studies In Sport And Exercise Science With Women As Participants Part Ii: Guidance For Applied Studies In Elite Female Athletes, Kirsty J. Elliott-Sale, Richard J. Burden, Kathryn E. Ackerman, Louise M. Burke, Naama Constantini, Anthony C. Hackney, Rachel Harris, Franco M. Impellizzeri, Xanne A.K. Janse De Jonge, Constance M. Lebrun, Clare Minahan, Sophia Nimphius, Stuart M. Phillips, Sarianna Sipilä, Juliette A. Strauss, Paul Swinton, Craig Sale

Research outputs 2022 to 2026

The purpose of this statement is to guide the design and conduct of high-quality sport and exercise science studies investigating the effects of varied ovarian hormone profiles on the health and athletic performance of elite female athletes. Beyond the menstrual cycle, these athletes present with a wide range of ovarian hormone profiles, including those associated with puberty and menarche, menstrual dysfunction, hormonal contraceptive use, pregnancy and postpartum, perimenopause, menopause and post-menopause. To effectively integrate knowledge of ovarian hormone profiles into high-performance sport and address the diverse needs of female athletes, future research and educational initiatives must encompass this broader spectrum …

Peptidomic Profiling Of In Vitro Digesta From Diverse Microalgae Species, Sara Hamzelou, Damien Belobrajdic, Henri Brook, Wei Chen, Fletcher Hiten, Kim Lee Chang, Diane Purcell, Utpal Bose, Simone Osborne, Cassandra Pegg, Michelle L. Colgrave

Research outputs 2022 to 2026

Microalgae are a sustainable protein source, yet few species are used for human nutrition. This study evaluated eight species for protein quality, digestibility, and peptide profiles after simulated gastrointestinal digestion using INFOGEST. Amino acid content, and intestinal-phase peptide mixtures were analysed by mass spectrometry. The methanol precipitation method was used to separate digested (supernatant) and undigested (pellet) peptides following in vitro INFOGEST digestion. The pellet was further separated by molecular weight into 3–10 kDa and >10 kDa fractions to isolate the lower molecular weight peptides from the higher ones. This separation method enabled the identification of potential digested peptides within …

The First Systematic Review Of Treatment Characteristics And Recidivism Outcomes For Indigenous People Who Have Sexually Offended, James L. Finney, Natalie Gately, Suzanne Rock, Braden Hill

Research outputs 2022 to 2026

It is of great importance that research investigates the impact of sexual offender treatment programmes given the damage caused by sexual offences to victims and society more broadly. However, psycho-criminological literature has focused on reporting post-treatment recidivism outcomes for people who have sexually offended homogeneously and has not investigated the unique experiences of Indigenous people. Therefore, we systematically collated and critically appraised studies reporting recidivism outcomes for Indigenous people who have received treatment for sexual offences. Fourteen studies were identified utilising a sample of 5,635 individuals (30.7% Indigenous or First Nations). Recidivism was lower for Indigenous and First Nations people …

A Multidimensional Evaluation Of Various Isometric Posterior Chain Strength Assessments: Comparative Force Production Characteristics, Administrative Feasibility, And Athlete-Reported Experience, Adam E. Sundh, Nicholas J. Ripley, Aj J. Lamb, Devin S. Vervoort, Paul Comfort

Research outputs 2022 to 2026

Isometric posterior chain strength assessments are increasingly employed in high-performance sports for benchmarking and fatigue monitoring, yet little is known about how practical implementation factors influence protocol selection. The aim of this study was to examine the feasibility, practicality, participant perceptions, and reliability of four commonly used isometric posterior chain assessments, the long-lever bridge (LLB), standing 90:20, supine 90:90, and supine 30:30. Thirty-seven NCAA division II athletes (19 females: age = 20.1 ± 0.9 years, height = 166.7 ± 5.2 cm, body mass = 67.0 ± 12.1 kg; and 18 males: 19.7 ± 1.2 years, height = 178.9 ± 6.6 …

Blue Poppy Study: Frequency Of Ptsd In The West Australian Police Force, Daniel Talbot, Peter Drummond, Christopher Lee

Research outputs 2022 to 2026

Objective: As exposure of police officers to traumatic incidents has increased in recent years, the aim was to determine the prevalence of post-traumatic stress disorder (PTSD) and associated distress in the West Australian (WA) Police Force. Method: Participants were 1,278 sworn officers from the Western Australia (WA) Police Force, recruited via advertisements placed in the WA Police Union newsletter. This sample represented approximately 18.5% of the WA Police workforce. PTSD symptoms were assessed using the PTSD Checklist for DSM-5 (PCL-5), administered through an online survey platform. This study employed a cross-sectional correlational design. Factors related to PTSD were assessed using …

Challenging The Monopoly Giant: Market Challenger Premium As Competitive Advantages, Cheuk Hang Au, Chih Yuan Chou

Research outputs 2022 to 2026

Market challengers frequently disrupt established incumbents with innovative ideas or novel business models. Yet, they frequently face high entry barriers and the entrenched power of incumbents. Even when challengers provide products or services better aligned with the market, competing effectively can remain difficult, particularly in monopoly-dominated sectors. This paper presents a case study of ViuTV entering Hong Kong’s monopoly-led free-to-air TV market. We identify IFH (innovation, freshness, hope) strategies for challengers to gain competitive advantage, leading to the emergence of a “market challenger premium” as a unique competitive edge. We also examine the role of customer cognitive biases and the …

A Contribution To Constructing A Theory And Model Of Social Work Leadership, Cheri Darlene Bilitz

Theses and Dissertations (Comprehensive)

Few schools of social work provide formal leadership education and training for emerging social workers—the research topic under exploration was how social work leaders constructed their leadership style. The purpose of the study was to develop a model of social work leadership through understanding leaders’ journeys into leadership and the contextual factors that shaped their leadership. Participants shared the qualities they believed were paramount for leading today and into the future. Seeing schools of social work as leadership incubators for emerging social workers, participants shared their suggestions for scaffolded leadership curriculum. The methodological approach for this research study was constructivist …

Moral Identity And Cognitive Mechanisms In Moral Decision-Making, Zachariah I. Hamzagic

Theses and Dissertations (Comprehensive)

Moral identity can be broadly conceptualized as the degree to which an individual places moral values as directly relevant to their personal identity. A recently introduced developmental framework of moral identity argues that moral identity can be conceptualized as a lifelong goal. According to this theoretical framework, the moral identity goal (i.e., to be a moral person and engage in moral action) becomes stronger over the course of development by becoming more abstract (i.e., general), internalized (to satisfy personal ideals) and promotion (i.e., action) oriented. Additionally, the strength of the moral identity goal predicts moral functioning. To date there has …

Picturing Your Goals: Examining Imagery Perspective And Self-Concordance In Goal Motivation, Cana J. Reuber

Theses and Dissertations (Comprehensive)

Mental imagery is often used as a strategy to increase motivation and support goal pursuit, but it remains unclear when different forms of imagery are most effective. Prior work suggests that adopting a third-person imagery perspective may enhance goal striving by promoting more abstract, identity-relevant processing. In line with this work, we predicted that third-person imagery would be most beneficial for self-concordant goals. The present research tested this prediction across three studies. In Study 1 (N = 273), participants identified a personal goal, visualized themselves pursuing and attaining it from either a first- or third-person perspective, and reported their …

Exploring Religious-Spiritual Struggles Among Muslim Immigrants In The Canadian Context, Ayse Erenay

Theses and Dissertations (Comprehensive)

Migration to a new culture and adaptation to a different lifestyle may cause emotional and psychological stress. In some cases, immigrants may experience religious and/or spiritual (R/S) struggles due to challenges to their beliefs and practices in the country they have immigrated to. Based on Pargament (2007, 2013)’s R/S struggle framework, these struggles may include questions about the ultimate meaning of life, one’s relationship with God, or doubt about one’s belonging within a religious or spiritual community. Muslim immigrants face unique struggles since Islamic teachings require Muslims to visibly practice their faith and reflect on God’s presence as a central …

The Power Of Letting Go: The Role Of Goal Adjustment Capacities Across Future And Daily Perspectives Of Chronic Illness, Alexandra Dagher, Meaghan Barlow

Theses and Dissertations (Comprehensive)

Goal adjustment capacities are self-regulatory processes that protect psychological well-being by allowing individuals to disengage from unattainable goals and reengage in new attainable ones. Although research has shown that these capacities are beneficial in the context of chronic illness, little is known about how their effectiveness may differ across various aspects of the chronic illness experience. The present research consisted of two distinct yet complementary studies examining the role of goal adjustment capacities in two chronic illness contexts. Study 1 (N = 149) prompted participants to imagine the future progression of a chronic illness, whereas Study 2 (N …

The Effects Of Appearance Change And Partial Face Visibility On Eyewitness Identification, Raina-Lynn A. Brock M.A., Judy Eaton Ph.D.

Theses and Dissertations (Comprehensive)

There is limited research examining the possibility of a temporary appearance change (e.g. a black eye) between exposure to a perpetrator at the time of a crime and later identification attempts by eyewitnesses. Across two experimental studies, this research examines how eyewitness identification decisions are impacted by an appearance change and how lineup procedures can influence eyewitness accuracy. Study 1 examined how a transient facial feature, a black eye, affects the accuracy of eyewitnesses’ identification decisions, while manipulating the severity of the black eye (prominent bruising, faded bruising, no bruising). Participants (N=403) were exposed to a 43-second mock crime video …

Fear Across The Map: A Cross-Municipal Analysis Of Fear Of Crime In Canada, Muhammad Ali

Theses and Dissertations (Comprehensive)

This study examines the predictors of fear of crime (FOC) across three Canadian municipalities: Hamilton, Ontario; Brantford, Ontario; and North Battleford, Saskatchewan. Data from 1,956 survey responses were analyzed to understand how certain factors shape FOC across different municipal contexts in Canada. This study uses descriptive statistics, reliability analyses, correlation matrices, and Ordinary Least Squares regression models to examine whether FOC, and the predictors of FOC, operate consistently across municipalities. The findings indicate that the predictors of FOC are relatively reliable across municipal contexts. However, the influence of the predictors of FOC can vary across municipalities. Importantly, the level of …

A Literature Review Of Adoptive Cell Therapy (Act) In Non-Small Cell Lung Cancer (Nsclc) With Emphasis On Chimeric Antigen Receptor (Car) T Cell And Tumor Infiltrating Lymphocyte (Til) Therapies, Brianna Wickham

Honors Program Theses

Non‑small cell lung cancer (NSCLC) accounts for the majority of lung cancer diagnoses and remains a leading cause of cancer‑related mortality despite advances in surgery, chemotherapy, radiation, and immune checkpoint inhibitors. While immunotherapy has improved outcomes for some patients, many develop treatment resistance or experience significant toxicity, highlighting the need for alternative therapeutic strategies. Adoptive cell therapy (ACT), which involves the infusion of autologous immune cells expanded or engineered ex vivo, has demonstrated substantial success in hematologic malignancies and is now being investigated for use in solid tumors such as NSCLC. This literature review examines the current state of ACT …

Exploring Parent-Child Reminiscing Style And Internal-State Talk When Discussing Positive And Negative Shared Events, Komal Verma Miss.

Theses and Dissertations (Comprehensive)

Conversations between parents and children about past events play a critical role in children’s social, emotional, and cognitive development. Parents scaffold their children in learning to recount details of their autobiographical memories by creating a space to reflect on internal states, specifically emotions and cognitions. Parents with an ‘elaborative’ reminiscing style are responsive to children’s utterances and ask open-ended questions (e.g., What do you remember about...?). Parents who are less ‘elaborative’ typically ask narrow questions like Did you like it?” that do not encourage conversation. Children whose parents use an elaborative reminiscing style have children who produce the most detailed …

Bovine Lactoferrin Maintains Antibacterial Effect Against Neonatal Escherichia Coli Septicaemia Isolates Despite The Presence Of Iron Acquisition Genes, Matthew Mayorga, Joshua L. Wheatley, Brianna N. Maldonado, Susana Chavez-Bueno

Student Publications

Introduction. Escherichia coli is a dominant cause of neonatal sepsis for which no prevention measures currently exist. Lactoferrin (LF) is an iron-sequestering antibacterial protein that has been noticed to decrease neonatal late-onset sepsis.

Hypothesis/Gap Statement. LF’s effect on in vitro growth of neonatal E. coli clinical isolates causing septicaemia is unknown. The prevalence of iron acquisition virulence genes which contribute to pathogenicity outcomes in these strains has also not been described in detail.

Aim. To evaluate bovine lactoferrin’s (bLF) effects on the in vitro growth of neonatal septicaemia E. coli isolates, and to determine the presence of iron acquisition …

Levonorgestrel Intrauterine System Use And The Risk Of Cervical Cancer In Women With Human Papillomavirus, Britney Margheim, Lauren Zakshorn, Sadie Wiens

Student Publications

No abstract provided.

Effects Of Short-Term Exposure To Environmentally Relevant Pesticides Mixture On Morphological Alterations, Oxidative-Nitrative Stress Biomarkers, Cellular Apoptosis, And Antioxidant Expression In Kidneys Of Goldfish, Esmirna Cantu, Md Saydur Rahman

School of Earth, Environmental, & Marine Sciences Faculty Publications

Chemical stressors are pervasive, affecting both terrestrial and aquatic environments. The continual influx of these toxins is damaging ecosystems and the organisms that inhabit them. The abundance of environmental toxins makes aquatic habitats inhospitable for aquatic life. These chemical stressors consistently disrupt the life processes of aquatic organisms, particularly their physiological functions. This study examined on the effects of environmentally relevant pesticides mixture (low-dose and high-dose: S-metolachlor: 2.4 go/L, 12 μg/L; linuron: 2.0 μg/L, 10 μg/L; isoproturon: 1.2 μg/L, 6.0 μg/L; tebucanozole: 1.2 μg/L, 6.0 μg/L; aclonifen: 0.8 μg/L, 4.0 μg/L; atrazine: 0.4 μg/L, 2.0 μg/L; pendimethalin: 0.4 μg/L, 2.0 …

A Preliminary Investigation Of Research Collaboration Through Scientific Paper Co-Authorship In The Gulf Of Mexico, Juliet Vallejo, Evelyn Roozee, Dongkyu Kim, Andrew M. Song, Christopher A. Gabler, Jasper R. De Vries, Antonia Sohns, Gordon M. Hickey, Owen Temby

School of Earth, Environmental, & Marine Sciences Faculty Publications

It is well known that publications with collaborators from external institutions increase citations. This effect scales with spatial distance. There are also many barriers to long-distance collaborations, including linguistic differences, funding constraints, and the incremental costs of remote collaboration. This paper uses the Gulf of Mexico as a case study to examine long-distance research collaboration because it consists of three countries with diverse development levels and two prominent diplomatic languages, within a singular regional ecosystem of tremendous natural and economic value. This paper uses bibliometric network analysis to examine scientific research article co-authorship in the Gulf of Mexico from 2000 …

The Impact Of Regional Fishery Management Organization Structure On Collaborative Performance, Evelyn Roozee, Owen Temby, Gordon M. Hickey

School of Earth, Environmental, & Marine Sciences Faculty Publications

Collaboration is integral to understand, plan, coordinate, and implement management measures for fisheries that cross international borders. Regional Fishery Management Organizations (RFMOs) are the main arenas for countries to collaborate and make decisions for transboundary fisheries, but these organizations have generally failed to prevent the depletion of some of the world's most valuable fish stocks. It is unclear how the structure and functioning of RFMOs can improve collaborative performance to better manage transboundary fish stocks. Using fuzzy-set qualitative comparative analysis, our study analyzes 10 RFMOs to identify the combination of six organizational conditions associated with high and low collaborative performance. …

Histochemical Alteration, Protein Nitration, And Antioxidant Expression In Oysters As Early Warning Indicators For Microplastic Contamination In The Texas Gulf Coast, Rebecca Muñiz, Md Faisal Amin, Md. Saydur Rahman

School of Earth, Environmental, & Marine Sciences Faculty Publications

Microplastics are widely distributed in aquatic environments and have been detected in numerous organisms. Marine bivalves are among the most affected aquatic organisms by microplastics due to their filter-feeding behavior. In this study, 60 oysters were collected from two sites along the Texas Gulf Coast. Fourier transform infrared (FTIR) spectroscopy and Nile red staining were used to detect microplastics in oyster (Crassostrea virginica) tissues. We compared field and laboratory samples collected after a two-week depuration period to identify differences in the shape and size of microplastics in oyster tissues. Results from the field sites showed a large number of microplastics, …

Real Time Waste Classification Using Deep Learning: Comparing Mobilenetv2 And Resnet 18 With Transfer Learning And Fine Tuning, Abdul Moaiz

ICT

Waste contamination is a major problem all over the world. The Environmental Protection Agency reports that over two thirds of waste found in general household and commercial bins could have been placed in the recycling or organic waste bins instead in Ireland, with food waste and plastics being the most common misplaced items. This project presents a deep learning solution to classify nine categories of waste from camera images in real time with the goal of helping users sort waste correctly at the source. Following the CRISP DM framework, two convolutional neural network architectures were trained and compared, MobilenetV2 and …

Bitcoin Prediction System Usind Machine Learning Techniques, Carolina Azevedo De Castro

ICT

This project investigated the use of machine learning techniques to predict short-term Bitcoin price direction using historical market data obtained from Yahoo Finance. Following the CRISP-DM methodology, the dataset was analysed, prepared, and transformed through feature engineering techniques including moving averages, volatility indicators, return measures and price position metrics. Multiple classification algorithms were evaluated, including Bayesian Classification, K-Nearest Neighbour, Decision Tree, Random Forest, Logistic Regression, Support Vector Machine and XGBoost. Several optimisation strategies were also tested, including feature selection, hyperparameter tuning, feature scaling and class weight balancing. Results showed that predicting short-term Bitcoin price movements remains challenging, with most models …