Digital Commons Network^™

Progressive Remodeling Of Global Protein Interaction Networks In A Mouse Model Of Tauopathy, Weiwei Lin, Sadhna Phanse, Sophie J F Van Der Spek, Noah Lampl, Morgan C Stephens, Zihan Wang, Joseph T Nigro, Alejandro Rondon Ortiz, Ryan Hekman, Anna Lourdes F Cruz, Rebecca Roberts, Lulu Jiang, Juan Botas, Andrew Emili, Benjamin Wolozin

Faculty, Staff and Students Publications

Neurodegenerative disease is marked not just by loss of proteins or cells, but by dynamic rewiring of macromolecular interaction networks that precede and drive pathology. Here, we present a temporally resolved, systems-scale map of multi-protein complex remodeling in a tauopathy model, integrating co-fractionation mass spectrometry, quantitative phosphoproteomics, and machine learning to decode phosphorylation-dependent shifts in protein interactomes across disease progression. This interactomic atlas serves as a resource to investigate functional assemblies, including MAPT-Dpysl2 and Cyfip1-actin, as well as ptk2b-Kars/Dars and ptk2b-Msn-Farsb-complexes, that modulate early disease phenotypes in vivo. Notably, it captures the composition, dynamics, and regulatory state of protein complexes …

Paradoxes Of Customary Land Formalization: A Comparative Study Of Papua New Guinea And Indonesia From A Political Anthropology Perspective, Adi Prasetijo

Antropologi Indonesia

This article studies the dynamics of customary land ownership in Papua New Guinea (PNG), where approximately 97 percent of land is collectively held by clans. Drawing on insights from political anthropology—particularly normative pluralism (Griffiths, 1986; von Benda-Beckmann, 2006), Polanyi's double movement (Filer, 2014), along with cosmological perspectives on land and identity (Weiner & Glaskin, 2007; Ingold, 2021), it analyzes how government efforts to formalize customary land through the Land Act 1996 and the Incorporated Land Groups (ILG) Act 2009 generate three principal paradoxes: (1) protection versus exclusion, (2) recognition versus commodification, and (3) negotiation versus rigidity. The study blends an …

Pressure-Induced Electronic, Structural And Optical Properties Of Ru-Linbo3 Perovskite: A Dft+U Study, Zahraa M. Saab, Hussein A. Miran

Baghdad Science Journal

Owing to its remarkable features, lithium niobate (LiNbO₃) has been deployed in wide range of applications. In this study, the structural, electronic, and optical properties of the pristine LiNbO₃ and Ru substituted B-site of LiNbO₃ were investigated by employing density functional theory approach (DFT) within CASTEP code based on (GGA-PBE). Moreover, different hydrostatic pressures (0, 5, 10, 15, and 20 GPa) were applied. The results revealed that the optimized lattice parameters and energy bandgap are in well agreement with the published results. Besides, the insertion of Ru atoms at Nb site of LiNbO₃ leads to …

Secure Medical Data Hiding Using Dwt, Qpso, And Lightweight Encryption, Aymen Mudheher Badr, Mohammed Layth Talal, Amal Sufiuh Ajrash, Wildan Jameel Hadi

Baghdad Science Journal

With the ever-increasing demand for secure transmission and storage of medical records in a healthcare system, quick and effective data protection techniques are required. In this paper, a new approach of using Speck-Cipher, Discrete Wavelet Transform (DWT), and Quantum-based Particle Swarm Optimization (QPSO) is proposed for the security of embedded medical data in medical images. The technique can also maintain good image quality and offers Speck-96bit to safeguard sensitive medical data with high noise & compression attack resistance (CR = 0.95). The results showed that the proposed method performs better, with a Peak Signal-to-Noise Ratio (PSNR) of 46.0 dB (Max …

Who Holds The Power: A Discourse Analysis Surrounding Human Trafficking, Maria Bernardo

The Compass

Narratives surrounding human trafficking in the United States have shaped public understanding through government, media, and non-governmental organizations (NGOs). Human trafficking is a complex global issue involving exploitation using force, fraud, or coercion for numerous purposes. Through the examination of intertextual relationships among government reports, victim narratives, and media coverage, this project aims to look at dominant narratives about human trafficking while comparing them to policy. While policy criteria describes indicators, literature argues how human trafficking is not clearly defined. A common issue in literature is the definition of a trafficked person. There is often a debate between what scholars …

Patriotism From The Past To The Present: Inclusive And Exclusive Pratriotism As Powerful Forces In American History And Trump’S Presidency, Nicole Burgon

The Compass

What is patriotism? Is it standing for the “Star-Spangled Banner” before every sports game? Is it displaying the American flag in front of a house? While Americans often associate patriotism with these symbolic gestures, American patriotism is an attitude that has been present since the start of our nation’s history. Patriotism can be defined as a feeling of devotion, attachment, commitment, or support for one’s country. It is, however, more than a single dictionary definition. In 1946, Merle Curti’s The Roots of American Loyalty traced American patriotism throughout history as “a pattern of emotions and ideas.” In a 1999 article …

The Compass, Issue 13, The Compass

The Compass

No abstract provided.

The Commercialization Of Wellness: Gray Market Peptides & Cancer, Bryan M. Burt

Advances in Cancer Education and Quality Improvement

No abstract provided.

The Oriental Religions In Roman Paganism, Franz Cumont

Hannah Arendt Marginalia - All

New York : Dover Publications, [1956]

Call #: BL805 .C8 1956

Contains underling and marginal lining

PDF information: 47 pages - 15.6 MB

The Greeks And Their Gods, Wkc Guthrie

Hannah Arendt Marginalia - All

Boston : Beacon Press, 1955.

Call : BL781 .G8 1955

Arendt copy contains underlining and marginal lining

PDF Information : 106 Pages, 53.2 MB

Kingship And The Gods : A Study Of Ancient Near Eastern Religion As The Integration Of Society & Nature, Henri Frankfort

Hannah Arendt Marginalia - All

Chicago ; London : University of Chicago Press, [1948]

Call #: BL325.K5 F7

Contains underlining and marginal lining

PDF information: 37 pages - 18 MB

Reconstructing The Administrative State In The Shadow Of The Unitary Executive, William Thomas Worster

ConLawNOW

The Supreme Court’s unfolding embrace of the unitary executive theory has now substantially restricted Congress’s ability to insulate administrative agencies from presidential control. In Trump v. Slaughter, the Court invalidated the Federal Trade Commission’s statutory removal protections and, in turn, shifted its substantial regulatory, adjudicative, and enforcement powers from independence to far more enhanced presidential supervision. The decision thus exposes a fundamental problem in the constitutional organization of, and legislative assumptions supporting, the administrative state, that have evolved over a substantial part of the nation’s history. Modern agencies are classified as “executive,” firmly placed within Article II under the …

The Shorthorn: August 12, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: August 11, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: July 28, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: July 26, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: July 14, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: June 30, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: June 23, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: June 21, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: May 31, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: April 28, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: April 29, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: April 21, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorhtorn: April 15, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: April 5, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: March 18, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: March 16, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: March 11, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: March 8, 1988

The Shorthorn Newspaper Collection: 1980s

No abstract provided.