Digital Commons Network^™

A Retrospective Cohort Study Of Uterine Cancer Epidemiological Analysis And Age-Based Disparities In Saudi Arabian Population Across 32 Years, Sallwa M. Alshehre, Mohammad A. Althubiti

Saudi Medical Journal

Objectives: To investigate the burden of uterine tumour in Saudi Arabia during the past 32 years (1990–2021), with an emphasize on the prevalence, incidence, mortality, and disability-adjusted life years (DALYs). Knowing these patterns strengthen the national aims of cancer control under Kingdom of Saudi Arabia (KSA) Vision 2030. Methods: A retrospective study was performed using data retrieved from the Global Burden of Disease (GBD) database. The work included population from Saudi Arabia between 1990 and 2021 and tested standardization age-specific metrics, involving uterine tumour incidence, prevalence, mortality, and DALYs. Results: Uterine tumour cases raised from 507 in 1990 to 6,366 …

Seroprevalence Of Hepatitis B And Hepatitis C In Patients Hospitalized In Palliative Care Service, Meryem Betos Koçak, Burcu Güler

Saudi Medical Journal

Objectives: Patients receiving palliative care often have complex comorbidities and frequent healthcare exposure, which may place them at risk for blood-borne infections such as hepatitis B virus (HBV) and hepatitis C virus (HCV). However, data on the seroprevalence and prognostic impact of these infections in palliative populations remain limited. This study aimed to determine the seroprevalence of HBV and HCV markers in patients hospitalized in a palliative care unit and to assess their association with mortality. Methods: This retrospective study conducted on 545 adult patients a tertiary palliative care unit between 2018 and 2024. Demographic characteristics, comorbidities, nutritional support, mobility, …

Impact Of Treatment On The Health-Related Quality Of Life Of Children With Cancer In Saudi Arabia, Fayzah Hussain Alhussain, Amany Anwar Saeed Alabdullah

Saudi Medical Journal

Objective: The impact of cancer on health-related quality of life (HRQOL) is considerable, particularly for children undergoing oncological treatment. While research has addressed HRQOL in childhood cancer survivors, less attention has been given to those actively undergoing treatment, including in Saudi Arabia. This systematic review aimed to address this gap by quantitatively evaluating studies reporting on the HRQOL of children in Saudi Arabia during their active cancer treatment phase. We also compare these findings with studies from around the world, emphasising demographic, medical and parental predictors of HRQOL. Methods: A comprehensive search of relevant databases (MEDLINE, CENTRAL, Embase, PsycINFO and …

Dream-State Consolidation Transformers For Long-Horizon Artificial Intelligence, Johny Manuel-Devadoss, Joanna Johnson, Jayden Jack Johnson

Defensive Publications Series

Contemporary transformer architectures achieve strong performance through large-scale parameterization, retrieval augmentation, and extended context windows. However, persistent token-level retention scales poorly for lifelong or long-horizon cognition due to increasing computational cost, retrieval interference, context fragmentation, and memory saturation. This paper proposes a speculative but computationally grounded framework termed Dream-State Consolidation Transformers (DSCT), in which artificial systems alternate between online inference phases and offline consolidation phases. During online operation, systems process high-resolution episodic information from external environments. During offline consolidation, episodic traces are replayed under stochastic perturbation and compressed into semantically stable latent representations.

Unlike conventional persistent-memory systems, DSCT prioritizes abstraction …

Biology Major Takes On Research And Collegiate Boxing In Senior Year, Devin Chivers

College of Arts and Sciences Newsroom

Beyond her genetics research in the lab, Ja’Brina Hargrave-Perkins trains and competes with UD’s boxing club.

A Novel Machine-Learning Based Method For Resolving Secondary Structure Topology In Medium-Resolution Cryo-Em Density Maps, Bahareh Behkamal, Mohammad Parsa Etemadheravi, Ali Mahmoodjanloo, Amin Mansoori, Mahmoud Naghibzadeh, Kamal Al Nasr, Mohammad Reza Saberi

Computer Science Faculty Research

Medium-resolution cryo-electron microscopy (cryo-EM) density maps preserve substantial information about protein secondary-structure organization; however, accurately recovering the topology and connectivity of α-helices and β-strands remains challenging due to noise, structural heterogeneity, and the intrinsic resolution limitations that obscure residue-level detail. Topology determination is a key intermediate step toward building atomic protein models from medium-resolution cryo-EM density maps. It requires identifying the correct correspondence and orientation between secondary-structure elements (SSEs), i.e., α-helices and β-strands, predicted from the amino-acid sequence and those detected in the three dimensional (3D) density map. Despite significant advances in cryo-EM reconstruction and molecular modelling, this correspondence problem …

Lgbtqia+ Inclusion In K-12 Education: A Systematized Review Of U.S. South Atlantic Region Educational Policy, Benjamin Little

Educational Specialist, 2020-current

LGBTQIA+ students experience disproportionate rates of discrimination, bullying, and mental health challenges within their educational settings, while educational policies shaping school climate vary considerably across jurisdictions. The purpose of this systematized review was to identify trends in the structure and implementation of LGBTQIA+ inclusion policies across K-12 state-level public education systems within the U.S. South Atlantic region and to examine how these policies addressed the needs of transgender youth and LGBTQIA+ students of color. This review synthesized publicly available state education documents, legislative materials, and nonprofit policy reports using a systematized review methodology guided by PRISMA principles and qualitative theme …

What’S Behind The Mask: The Diagnostic Divide In The Female Autism Phenotype, Shelley Gies Alston

Educational Specialist, 2020-current

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by differences in social communication and restrictive, repetitive behaviors; however, women are diagnosed at significantly lower rates than men. This study examined whether DSM-5-TR diagnostic practices may contribute to the underdiagnosis and delayed identification of ASD in individuals assigned female at birth (AFAB), with attention to masking behaviors, gendered social expectations, and clinician interpretation of symptoms. Grounded in the Female Autism Phenotype (FAP), a retrospective mixed-methods study surveyed 12 AFAB individuals aged 18–24 who self-identified or were formally diagnosed with ASD. Participants completed a 44-item online survey including Likert-scale and open-ended …

Decolonizing The Home: Anti-Racist Parenting In Asian American Families And Its Effects On Children's Mental Health, Danielle Angela R. Soriano

College Honors Program

Few studies in the field of psychology have investigated how anti-racist and anti-colonial parenting styles are practiced, especially within the Asian American community. The current study aims to investigate how anti-colonial and anti-racist parenting practices are explicitly manifested and their relationship with mental health in Asian American communities. This study concludes by proposing new directions in literature and exploring how anti-colonial approaches can support positive mental health outcomes in children and adolescents. By borrowing questions from the California Department of Education Parent Engagement Module Series and developing new items tailored to our participants’ demographics, we found that the majority (n …

Care As Method: Sound, Duration, Relation In Contemporary Art Practice, Violet L. White

MFA in Visual Art

Abstract Care as Method: Sound, Duration, and Multispecies Relation in Contemporary Art Practice

This thesis proposes care as a method of artmaking, not a subject, theme, or aesthetic position, but the actual structural logic through which a body of work is built, sustained, and understood. Working at the intersection of ecological art practice and relational aesthetics, it asks what happens when the encounter at the center of the work is not between two people but between species, infrastructures, and histories of use and what obligations that encounter generates.

The argument is developed through six interconnected works: installations, sound compositions, sculptures, …

A Kantian Guide To Understanding Agentic Ai And Its Ethical Consequences, Amelia Wang

Senior Honors Papers / Undergraduate Theses

The rapid emergence of Agentic AI, which are systems capable of autonomous, multi-step decision-making with minimal human oversight, has prompted growing discourse and concern regarding whether such systems possess a form of agency comparable to that of human beings, and subsequently, what ethical responsibilities ensue if they do. This thesis argues that many of the ethical risks surrounding Agentic AI stem from a fundamental misconception, which is the tendency to describe these systems using the language of agency ("deciding," "acting," "choosing") without examining whether they satisfy the philosophical conditions for genuine rational agency. Drawing on Immanuel Kant's Groundwork of the …

Psychometric Framework For Coexistence With Large Carnivores, Benjamin Ghasemi, Gerard Kyle, Tara Teel, Rebeca Niemiec, Kevin Crooks, Jenny Anne Glikman, Neil H. Carter, John A. Vucetich, Michelle L. Lute, Stewart Breck, Beatrice Frank, Dana Hoag, Jonathan Salerno, Lily M. Van Eeden, Jeremy T. Bruskotter

Michigan Tech Publications

Human–carnivore coexistence is essential for biodiversity conservation, yet measuring the attitudes and behaviors that support it remains methodologically challenging. We developed psychometric scales to assess willingness to coexist with carnivores and the underlying beliefs of this coexistence through an iterative expert elicitation process grounded in risk perception theory and moral psychology to ensure strong content validity. The scales measure willingness to coexist and encompass individual and collective behaviors and their cognitive antecedents: perceived positive consequences, perceived negative consequences, and ethical considerations. We validated the scales based on three representative samples of Colorado residents (n = 434, 442, 433) focused on …

Past, Present, And Future For The Children's Oncology Group (Cog) Renal Tumor Committee Trials, Nicholas Cost

Grand Rounds

At the conclusion of this activity, learners will be able to:

1. Describe COG Renal Tumor Committee.
2. Discuss outcomes from the last generation of COG Renal Tumor studies.
3. Examine current and next generation of COG Renal Tumor studies

Psy 1100 Writing Intensive Syllabus, Jos Khan

Open Educational Resources

This is an ZTC/OER syllabus for a PSY 1100 writing intensive course at Kingsborough Community College.

Thrombin-Induced Myofibroblast Differentiation Is Regulated By Myocardin And Novel Effector Genes In Ipf Fibroblasts, Christiana Okeke

Biotechnology Theses

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by fibroblast activation, excessive extracellular matrix (ECM) deposition, and irreversible respiratory decline. In this study, we investigated the role of myocardin and its downstream effectors, RGS5, DLGAP5, and TAGLN, in thrombin-induced myofibroblast differentiation and ECM remodeling using primary human IPF fibroblasts. Myocardin knockdown significantly attenuated thrombin-induced expression of profibrotic genes, including FN1, COL1A1, PAI-1, ACTA2, and CNN1, as well as the novel effectors RGS5, DLGAP5, and TAGLN, confirming myocardin as a central regulator of fibrotic signaling. Silencing RGS5 produced minimal effects on gene and protein expression despite minor downward …

Identification Of Proteins With Immune Stimulatory Activities From The Culture Filtrates Of Nontuberculous Mycobacteria, Christian Albert Agyei Acheampong

Biotechnology Theses

Nontuberculous mycobacteria (NTM) are the mycobacterial species other than Mycobacterium tuberculosis, which causes tuberculosis, and Mycobacterium leprae, which causes leprosy. Diseases caused by NTM are on the rise in the United States and are steadily becoming a significant public health problem globally, particularly in developed countries. Despite the ability of NTM pathogens to interact with the host immune system, the proteins responsible for eliciting host immune responses remain unidentified, making the accurate and timely diagnosis of the disease a challenge. In this study, we tested the hypothesis that NTM strains secrete proteins that stimulate immune responses. Our study …

Mapping And Framing Circular Economy In The Sixth Assessment Report Of The Intergovernmental Panel On Climate Change: A Systematic Text Analysis, Marta Castellini, Nadezhda Ushakova, Sergio Vergalli

Fondazione Eni Enrico Mattei Working Papers

Although the circular economy (CE) is recognised as a key climate mitigation strategy, its integration within global climate frameworks, such as those developed by the Intergovernmental Panel on Climate Change (IPCC) in its Assessment Reports, remains unclear. This study provides a systematic analysis of how the circular economy is framed in the climate-mitigation context of the IPCC Sixth Assessment Report using a mixed-methods approach that combines computational text analysis with qualitative content analysis through sentence-level manual coding. Eight Chapters relevant to the mitigation were examined and findings show that CE is most frequently framed as a supporting strategy (44.3%), followed …

First Recombinant Expression, Purification, And Film Formation Of A Single Solitary Bee Silk Protein From Osmia Lignaria, Oran Wasserman, Kristin K. Durrant, Jackson J. Morley, Paula E. Oliveira, Mallory R. Wootton, Brianne E. Bell, Ethon D. Van Noy, Randolph V. Lewis, Justin A. Jones

Biology Student Research

Solitary bees account for most described bee species worldwide, with many spinning silk fibers to form protective cocoons during development; however, solitary bee silk proteins remain largely unexplored in recombinant systems and biomaterial fabrication. Here, we report the first recombinant expression and biomaterial formation from a solitary bee silk protein. Osmia lignaria silk fibroin 2 (OligF2) was expressed in Escherichia coli BL21(DE3) using an expression and purification scheme adapted from a recombinant hagfish intermediate filament (rHIF) workflow, yielding 0.34 g/L at ~70% purity. The purified OligF2 protein was cast into films at 0.75% and 1% (w/v). …

Underlying Mechanisms In The Relationship Between Ptsd And Irritable Bowel Syndrome, Jillian B. Heymann

Dissertations

Current bodies of knowledge support the relationships between posttraumatic stress disorder (PTSD) and irritable bowel syndrome (IBS), pain catastrophizing and PTSD, and pain catastrophizing and IBS. However, much less is known regarding how pain catastrophizing influences the relationship between PTSD and IBS. Additionally, while correlations between some demographic and trauma-related symptomatology have been elucidated in the relationship between PTSD and IBS, their impact as potential moderators on the relationship between PTSD and IBS has yet to be fully examined. Examining a student sample from a large midwestern university, the present study aimed to investigate the potential mediating and moderating roles …

Cardiac Hdac3 Disruption Contributes To Hdac Inhibitor-Induced Qt Prolongation, Jiao Lu, Christopher Ward, Sichong Qian, Lilei Zhang, Jiang Chang, Zheng Sun

Faculty, Staff and Students Publications

Histone deacetylase (HDAC) inhibitors are approved for cancer treatment and are being investigated for a wide range of other diseases. Despite their therapeutic promise, clinical studies have reported cardiac side effects, particularly electrocardiogram (EKG) abnormalities, with QT interval prolongation being one of the most consistently reported findings. The mechanisms underlying these cardiac effects remain unclear. In this study, we investigated the role of HDAC3 in cardiac electrophysiology. We found that postnatal depletion of cardiac HDAC3 in mice caused QT interval prolongation, recapitulating the EKG abnormalities reported with HDAC inhibitor use. Adult-onset inducible depletion of cardiac HDAC3 induced additional EKG abnormalities, …

Contested Surveillance: Gendered Citizenship And Political Participation In Egypt And Lebanon, Mohamad Zarif

Theses and Dissertations

While the 2011 Arab Uprisings were famously framed by the utopian narrative of a 'Facebook Revolution', this view has given way to a dystopian reality in which digital infrastructures can facilitate authoritarian retrenchment. This thesis interrogates how lowermiddle- and working-class precarious youth navigate and perceive this "Architecture of Control" in Cairo and Beirut. Using a comparative qualitative design with purposive and snowball sampling, this research integrates digital ethnography and fourteen interviews with eighteen participants (nine women, seven men) to capture lived experiences of surveillance rather than the internal logic of state security institutions. The study yields three primary findings. First, …

Peer-Led Team Learning: Transforming The Introductory Colsa Experience, Derek Edry

UNH Today Archive

No abstract provided.

Be Prepared For Your Nurse Practitioner Clinical Readiness Exam, Elizabeth Heavey, Renee Biedlingmaier, Colleen Burgoyne, Carnel C. Jackson

Milne Open Textbooks

This text contains case studies and review questions for nurse practitioner students; focusing on the 3Ps of nurse practitioner education (Pharmacology, Pathophysiology, and Physical (Health) Assessment) to help NP students prepare for their clinical courses and pass their clinical readiness exam.  It includes cases commonly seen in entry-level NP practice.  In addition to the three individual sections of the text that focus on cases applying content from each of the distinct courses (Pathophysiology, Pharmacology, and Physical Assessment), we included summative case studies at the end of the book that connect all three areas in a single case. Because these three …

Treatment Of Different Non-State Actors In Detention: A Legal, Moral, And National Security Analysis, Alison P. Raedel

Senior Honors Projects, 2020-current

This thesis analyzes state behavior regarding the treatment of non-state actors through three major frameworks: international law, ethical theory, and national security. Two cases are compared: the treatment of al-Qaeda detainees by the United States after the attacks of September 11th, 2001, and the treatment of the Angolan liberation movements by the Portuguese during the Angolan War of Independence. These cases were chosen to assess how the three frameworks apply across different non-state actors, which include terrorist organizations and liberation movements. International law provides a baseline for rights and protections, but it is often selectively interpreted. Just war theory gives …

Quality Care For Neurodivergent Youth, Emily V. Bogaev

Dissertations, 2020-current

Neurodivergent youth are becoming increasingly present in counseling settings, yet many counseling approaches have historically been shaped by deficit-oriented frameworks that conceptualize neurodivergence as something to be corrected. These perspectives may overlook the lived experiences and strengths of neurodivergent individuals. The purpose of this dissertation was to examine neurodivergence in counseling through three complementary manuscripts addressing conceptual foundations, youth perspectives, and counselor preparation. The first manuscript is a conceptual article that explores neurodivergent-affirming counseling and contrasts affirming frameworks with traditional deficit-based approaches. The second manuscript utilized a qualitative narrative inquiry design to explore neurodivergent youths’ perceptions of neurodivergence and the …

Louisiana State University Health Sciences Center - 2026 - 153rd Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 153rd Commencement of LSU Health Sciences Center - New Orleans held May 14, 2026.

Environmental Dna (Edna) Assessment Of Fish And Decapod Diversity And Their Association With Cetacean Distribution In Matang Coastal Waters, Perak, Lim Chuan Hui

Student Works (2020-2029)

The estuarine and coastal regions of Matang, Perak, Peninsular Malaysia, are vital fishing grounds and recognised biodiversity hotspots, but are increasingly exposed to human activities. Understanding the biodiversity of marine fish and decapods is crucial for effective conservation efforts. Conventional biodiversity monitoring methods face several challenges, including invasiveness, inconsistencies in sampling techniques, reduced taxonomic accuracy, time-consuming processes, high costs, and often only providing approximate estimates. In this study, we evaluated the use of environmental DNA (eDNA) metabarcoding to assess marine fish and decapod diversity in Matang waters and to explore possible associations between fish assemblages and local cetacean occurrence. Water …

Exploring Spike-Dependent And Ace2-Independent Sars-Cov-2 Interactions With Salivary Epithelial Cells In The Absence Of Ace2, Caitlynn M L Barrows, Thaise C Geremias, Simon Young, Mary C Farach-Carson

Faculty, Staff and Student Publications

Salivary gland infection by SARS-CoV-2 requires viral entry via routes and mechanisms that remain unresolved. This study examined the expression of the angiotensin-converting enzyme 2 (ACE2) receptor in salivary tissues and basal cell-derived human salivary progenitor cells (hS/PCs), an unstudied potential entry point for SARS-CoV-2. Multiple detection modalities, including immunocytochemistry, Western blotting, flow cytometry and RT-PCR, demonstrated a consistent lack of ACE2 protein and transcript in both tissue specimens and primary salivary epithelial cells. Antigen retrieval at pH 9 was determined to be optimal for immunodetection protocols, yet ACE2 remained undetectable. Small intestine tissue served as a positive control, confirming …

Elementary Students' Science Attitudes And Teachers' Implementation Of The Ngss Science Practices: A Mixed Methods Study, Michelle Laborn

Dissertations

It has been recorded in the literature that student science interest drops as students enter and transition to middle and high school. This dissertation takes up the areas of student science interest and the teaching of the science practices in the context of elementary education. This study seeks to understand student science interest in elementary students in the years before entering middle school where a drop of interest is frequently reported. It is hypothesized that an increased use or implementation of the NGSS science practices by classroom teachers would generate higher science interest in elementary students. In a framework of …

Pedagogical Possibilities Toward Positive Embodiment: Applying The Developmental Theory Of Embodiment To Educational Contexts, Elena Buis

Dissertations

Young adolescents, particularly girls, often experience uncomfortable and negative relationships with their bodies, contributing to negative physical, mental, and emotional outcomes. Although educators have implemented interventions to address this issue, those grounded in positive embodiment remain underexplored. Specifically, the Developmental Theory of Embodiment (DTE), a prominent framework in eating disorder and body image research, has not been integrated into educational research or practice. This dissertation explores the integration of DTE into educational theory, practice, and pedagogy across three complementary articles and examines the teaching and learning of Be Body Positive (BBP), a positive embodiment intervention, with a fifth grade Girl …