Digital Commons Network^™

Investigation Of Mercury Bioaccessibility In Subsistence Fishes From The Canadian Subarctic, Kiran Mateo Sharma Mr

Theses and Dissertations (Comprehensive)

Fish consumption is the primary pathway for human exposure to methylmercury (MeHg), a global contaminant of concern known to cause adverse health effects. Fort Albany First Nation, a remote Indigenous community in northern Ontario that relies on fish for both subsistence and cultural practices, has expressed concern regarding the safety of local fish consumption. Community members and leaders have communicated several priorities for scientific research that are the foundation of this thesis. Specifically, consumers of wild-caught fish have asked how traditional cooking methods may affect mercury concentrations in fish, and how mercury concentrations in little-studied organs, such as liver and …

Is Prosocial Behavior A Unique Correlate Of Academic Success In Emerging Adulthood?, Jacqueline Di Biase

Theses and Dissertations (Comprehensive)

Prior developmental research has frequently linked prosocial behavior to stronger academic functioning during childhood and adolescence (Cruz et al., 2024; Gerbino et al., 2018; Oberle et al., 2022), yet its relevance to academic success in emerging adulthood remains unclear. Guided by a Positive Youth Development (PYD) framework, the present study sought to address gaps in emerging adulthood research by examining the academic relevance of prosocial behavior while accounting for influential developmental assets and testing its independent contribution to academic achievement. Undergraduate students (N = 501) completed a cross-sectional self-report survey assessing prosocial behavior, self-control, dutifulness, sociability, and cumulative grade …

Nanoparticle Carriers Enhance The Prophylactic Antiviral Effects Of Dsrna In Vitro And Ex Vivo, Shayne Oberhoffner, Stephanie Dewitte-Orr, Starla Richardson, Leah Haile, Dominique Daniels, Erin Cooper, Aizah Ijaz, Janet Velasquez Perez, Mathilde Peruzzi, Bertrand Collet, Paul Craig, Kristof Jenik

Theses and Dissertations (Comprehensive)

Aquaculture now outpaces traditional capture fisheries as the world population and demand for sustainable protein sources increases. Wild and farmed species are increasingly susceptible to pathogen spread as global temperatures rise and stocking densities increase. Despite the devastating losses experienced by aquaculture due to viral infections, there remain few effective prophylactic antiviral therapeutics. Long double-stranded (ds)RNA is a uniquely viral molecule produced by nearly all viruses during their replication cycle, and its detection by salmonids like rainbow trout (Oncorhynchus mykiss) and chinook salmon (Oncorhynchus tshawytsha) leads to the establishment of a defensive antiviral state. Previous in vitro studies demonstrated a …

Implementation Of A 3-Dimensional Hydrodynamic Numerical Model On A Large Northern Lake, Kirin Lorente

Theses and Dissertations (Comprehensive)

Climate change is impacting high latitude regions disproportionately more than those at a lower latitude. With polar lakes being highly sensitive to changes in the climate, shifts in lake ice dynamics and hydrodynamics are indicators of such changes in regional and global climates. These changes impact future seasons in a positive feedback loop, where changes in winter ice cover impact open water nutrients levels and lake thermal structure. This highlights the importance for long-term monitoring. Despite the abundance of lakes distributed across Northern Canada, there has been limited research conducted on these sentinels of climate change.

Specifically, Great Bear Lake …

" Who Am I Here?" Exploring The Racial Identity Development Of Chinese Adolescent International Students In Canada: A Constructivist Grounded Theory Approach, Wen Juan Song

Theses and Dissertations (Comprehensive)

Abstract

This dissertation explores the racial identity development and associated mental health challenges of Chinese Adolescent International Students (CAIS) in Canada, a population navigating complex intersections of race, age, migration, and belonging. Despite their growing presence in Canadian secondary education, CAIS remain understudied in both educational and mental health research, particularly in relation to racial identity development within Western, multicultural societies. Using a Constructivist Grounded Theory methodology, this study draws on in-depth interviews with twenty-five CAIS participants, including ten current high school students, three returnees to China, and twelve who remained abroad in post-secondary education or employment.  The study is …

Geovig And Purevig: Geometry-Aware Architectures For Efficient Computer Vision, Omar Ismail

Theses and Dissertations (Comprehensive)

Deploying deep learning models for medical image analysis on mobile devices requires a balance between inference latency, memory footprint, and delineating anatomical boundaries with high accuracy. While Convolutional Neural Networks (CNNs) and mobile Vision Transformers (ViTs) offer efficiency, they often struggle to model the irregular, non-local geometric structures inherent in biological tissues without incurring prohibitive computational costs. In this thesis, we introduce GeoViG (Geometric Vision Graph), an architecture that bridges the gap between efficient grid-based processing and explicit Geometric Deep Learning. GeoViG introduces a novel transition from high-resolution pixel grids to low-resolution dynamic graphs via a SpreadEdgePool operator, a geometry-aware …

Investigating The Immunostimulatory Potential Of Dsrna-Silk Nanoparticle Complexes In Melanoma, Samuel J. Peters

Theses and Dissertations (Comprehensive)

The rate of resistance to immune checkpoint inhibitor treatment in metastatic melanoma is quite high, with an overall rate of 70%. Melanoma achieves these high rates of resistance by suppressing the immune response in the tumour microenvironment (TME), making them immunologically “cold”. The type 1 interferon response could be leveraged to initiate immune responses in melanoma, making their “cold” TMEs “warm” again. Double-stranded ribonucleic acids (dsRNAs) are potent activators of an innate immune response; however, they are susceptible to degradation by nucleases present in the body and need a carrier. Silk nanoparticles (SNPs) are an ideal drug-delivery platform as they …

The Impact Of Regional Fishery Management Organization Structure On Collaborative Performance, Evelyn Roozee, Owen Temby, Gordon M. Hickey

School of Earth, Environmental, & Marine Sciences Faculty Publications

Collaboration is integral to understand, plan, coordinate, and implement management measures for fisheries that cross international borders. Regional Fishery Management Organizations (RFMOs) are the main arenas for countries to collaborate and make decisions for transboundary fisheries, but these organizations have generally failed to prevent the depletion of some of the world's most valuable fish stocks. It is unclear how the structure and functioning of RFMOs can improve collaborative performance to better manage transboundary fish stocks. Using fuzzy-set qualitative comparative analysis, our study analyzes 10 RFMOs to identify the combination of six organizational conditions associated with high and low collaborative performance. …

Biomarkers Of Foraging And Reproduction In Captive Adult Female Hawksbill Sea Turtles (Eretmochelys Imbricata), Joslyn Blessing Kent, Kari Renee Dawson, Shingo Fukada, Masae Makabe, Isao Kawazu, Ken Maeda, Roldán A. Valverde

School of Earth, Environmental, & Marine Sciences Faculty Publications

Hawksbill sea turtles (Eretmochelys imbricata) are listed as critically endangered by the International Union for the Conservation of Nature (IUCN). To implement best conservation practices for this species, its biology should be well understood. Attempting to characterize the foraging physiology of free-ranging hawksbill sea turtles is complicated by the fact that sampling is typically limited to nesting females during the reproductive season. Without data from non-reproductive periods, it is difficult to determine whether observed physiological values reflect baseline conditions or are specific to the energetically demanding nesting season. Accordingly, in this study, we described the physiology of foraging in …