Digital Commons Network^™

Chasing Disinfection Byproducts Through The Pipes: How 66 Dbps Change Over Time In Chlorinated Vs. Chloraminated Distribution Systems, Erik Niehaves, Patrick T. Justen, Ashley A. Perkins, Alexandria L.B. Forster, Caroline O. Granger, Susan D. Richardson

Faculty Publications

While disinfection byproducts (DBPs) are typically measured at drinking water treatment plants, levels can change dramatically within the distribution system before reaching the consumer. In this study, the spatio-temporal trends of 66 DBPs across 9 different classes were examined in two drinking water distribution systems with similar source waters, but different pretreatments and residual disinfectants. One system uses residual chlorine in the distribution system, and the other uses chloramine, allowing for examination of how DBP concentrations change over time in distribution systems with different residual disinfectants. Four routes were sampled for each system with six time points over three days …

Volume 34, Number 3, Winter 2025/26, Office Of Communications, Illinois Wesleyan University

Illinois Wesleyan University Magazine, 2018-present

VOLUME 34 | NUMBER 3 | Winter 2025/2026

ON OUR COVER:

Elliot Notrica '26 is developing micro-organisms that create new food products from food waste like cocoa husks and leftover bread dough.

18 Found Families. Celebrate one of the best-attended IWU Homecoming Weekends with stories of alumni friendships across the decades.

22 The Future of Food. Elliott Notrica '26 is the founder and CEO of Symbio Bioculinary where he is creating the future of food with cutting-edge genetic engineering.

26 Hope in Crisis. EmPath units, invented by Scott Zeller '82, are revolutionizing emergency care around the world.

Eng 3604e-710 Public Writing And Women’S And Gender Studies, Elizabeth Tacke

Spring 2026

No abstract provided.

Improving Stem Assessments: Strategies For Increasing The Accessibility And Adoption Of Two-Stage Exams, Kristina Callaghan

LSU Doctoral Dissertations

Over three decades of research have shown that students taught using active learning strategies achieve better learning outcomes compared to those taught using traditional methods. Two-stage exams, which pair a traditional exam with a group component, are an increasingly popular method for incorporating active learning within the assessment component of a course. Previous studies have shown this assessment strategy provides a variety of benefits for students, including increased engagement and collaboration, immediate feedback, and potentially increased content retention. However, the unique circumstances of each instructor can pose a non-trivial barrier to the implementation of two-stage exams. In this thesis, we …

Teriparatide Use In Osteopenic Patients Undergoing Single-Level Lumbar Fusion Associated With Decreased 2-Year Revision Rates, Mitchell K. Ng, Ariel N. Rodriguez, Abigail Razi, Ahmed K. Emara, Brian T. Ford, Ameer Tabbaa, Divya Gouni, Jacquelyn J. Xu, Paul G. Mastrokostas, Jad Bou Monsef, Afshin E. Razi

Rothman Institute Papers

Context:  Low bone density is common among lumbar fusion patients and increases the risks of pseudarthrosis, hardware failure, and revision. Teriparatide improves bone mass and fusion in osteoporosis, but its benefit in osteopenia or normal bone remains uncertain.

Aims:  To evaluate the association between teriparatide exposure and (1) postoperative complications, (2) 90-day readmission, and (3) 2-year reoperation, stratified by bone health status (osteoporotic, osteopenic, and normal) in patients undergoing single-level lumbar fusion.

Setting and Design:  A retrospective cohort study using the PearlDiver database from 2010 to 2021 identified patients undergoing single-level lumbar fusion.

Subjects and Methods:  Patients on teriparatide were …

Improving The Well-Being Of Mothers Of Infants And Toddlers Through Mindfulness And Creativity, Tia L. Curran

Mindfulness Theses

U.S. mothers of infants and toddlers report experiencing feelings of confusion surrounding their identity in early motherhood. Research also shows emotion dysregulation, cognitive overwhelm, attention issues, high stress and isolation as common challenges mothers of toddlers and infants experience in their daily lives. These challenges can directly impact a mother’s well-being as well as her child’s well-being and the entire family unit. Mindfulness practice and creative expression are two ways of being that relate directly to each other and have been shown to improve well-being. Through repeated exercising of mindfulness and creativity, one can regulate their emotions and reduce stress …

Complexity Mindsets, Complex Flow, And More: A Qualitative Grounded Theory Study On The Phenomenon Of Practitioners Working Within Complex Social Systems, Emma D. Stellman

Educational Studies Dissertations

This qualitative grounded theory study addressed gaps in the literature regarding the application of complexity theory to complex social phenomena (CSP), for which no straightforward solutions or simple interventions exist. While complexity theory has played an important role in groundbreaking innovations in quantitative fields such as medicine, engineering, and finance, its application remains limited in human-centered developmental domains including education, social work, and healthcare. Using a grounded theory design informed by phenomenological approaches, this study examined the lived experiences of a group of six CSP practitioners, each of whom participated in two individual, semi-structured video interviews. Interview data were analyzed …

Why Agtech Startups Fail? Evidence From Global Shutdown Patterns In 2025 And The Cost-Adoption Mismatch Effect, Ankit Chandra, Ishani Lal

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Agricultural technologies are widely seen as a driver for sustainability, resilience, and food-system transformation. Yet in 2025, agtech startup across North America, Europe, Asia, and Africa experienced multiple shutdowns. Although each company closed for its own reasons, the failures highlight consistent underlying patterns. We analyze 18 publicly reported shutdowns across controlled-environment agriculture (CEA), robotics, insect protein, digital platforms, sensors, and ag-biotechnology. We find that most ventures struggled not with scientific feasibility but with economic and adoption dynamics at the farm level. We identify a Cost-Adoption Mismatch Effect, in which the capital and operational burden of a technology exceeds farmers’ capacity …

The Impact Of Vdr Gene And Biochemical Indicators In Osteoporosis, Sabah Subhi Ismael Barani, Mohammed Abdullah Ajeel, Safwan Jasim Sultan

BioMed Visions Journal

Osteoporosis is a disorder caused by bone remodeling imbalance in which bone resorption outpaces bone production, resulting in weaker bone structure. Factors such as heredity and insufficient calcium and vitamin D consumption.

This study included an examination of 80 female patients of different ages (40–58 years) in Mosul. The participants were divided into two groups: 20 individuals served as the control group, while the rest 60 were osteoporotic women based on clinical cases and taking X ray DEXA. The blood samples are divided into two parts serum for biochemical tests and blood for genetic diversity in genes associated to Vitamin …

Sirtuins And Cartilage Preservation: From Cellular Function To Therapeutic Innovation, Muthanna K. Zaki, Khalil A. Hadid, Mohammed N. Abed, Fawaz A. Alassaf

BioMed Visions Journal

The bones are cushioned by a thin layer of hyaline cartilage that permits physical activity to be performed without experiencing any discomfort. However, these tissues are susceptible to several diseases involving osteoarthritis and rheumatoid arthritis resulting in cartilage degradation. Sirtuins (SRTs) and SRT-activating molecules have been shown in previous studies to affect cartilage and chondrocytes positively. This review aims to explore the potential protective effects of SRTs on cartilage and chondrocytes. It also highlighting various SRT-activating substances and their potential therapeutic applications in managing cartilage-related diseases. Google Scholar, Cochrane Library, and PubMed were used to search about related studies. The …

Neural Rewiring Of Resilience: The Effects Of Combat Deployment On Functional Network Architecture, Noga Yair, Tom Zalmenson, Omer Azriel, Dana Shamai-Leshem, Yaron Alon, Niv Tik, Lucian Tetse-Laur, Ariel Ben-Yehuda, Daniel Samuel Pine, Anderson M. Winkler, Ido Tavor

School of Medicine Publications

Background: Although combat-deployed soldiers are at high risk for developing trauma-related psychopathology, most will remain resilient for the duration and aftermath of their deployment tour. The neural basis of this type of resilience is largely unknown, and few longitudinal studies exist on neural adaptation to combat in resilient individuals for whom a pre-exposure measurement was collected. Here, we delineate changes in the architecture of functional brain networks from pre- to postcombat in psychopathology-free, resilient participants.

Methods: Tier 1 infantry recruits (n = 50) participated in this longitudinal, functional magnetic resonance imaging study together with a comparison group of university students …

Whole Genome Sequence Analysis Of Pulmonary Function And Copd In 44,287 Multi-Ancestry Participants, Wonji Kim, Lucinda Antonacci-Fulton, Susan K Dutcher, Et Al.

2020-Current year OA Pubs

BACKGROUND: Whole genome sequence (WGS) data in multi-ancestry samples supports discovery of low-frequency or population-specific genetic variants associated with chronic obstructive pulmonary disease (COPD) and lung function.

RESULTS: We performed single variant, structural variant, and gene-based analysis of pulmonary function (FEV

CONCLUSIONS: Large-scale multi-ancestry WGS analysis improves variant discovery and fine-mapping resolution for lung function and COPD and highlights biologically relevant genes and pathways.

Anoikis Resistance And Metastasis Of Ovarian Cancer Can Be Overcome By Cdk8/19 Mediator Kinase Inhibition, Mehri Monavarian, Resha Rajkarnikar, Emily Faith Page, Asha Kumari, Liz Quintero Macias, Felipe Massicano, Nam. Y. Lee, Sarthak Sahoo, Nadine Hempel, Mohit Kumar Jolly, Lara Ianov, Elizabeth Worthey, Abhyudai Singh, Igor Roninson Ph.D., Eugenia Broude Ph.D., Mengqian Chen Ph.D., Karthikeyan Mythreye

Faculty Publications

Anoikis resistance, or evasion of cell death triggered by matrix detachment, is a hallmark of cancer cell survival and metastasis. We showed that repeated exposure to suspension stress followed by recovery under attached conditions leads to development of anoikis resistance. The acquisition of anoikis resistance was associated with enhanced invasion, chemoresistance, and immune evasion in vitro and distant metastasis in vivo. This acquired anoikis resistance was not genetic, persisting for a finite duration without detachment stress, but was sensitive to CDK8/19 mediator kinase inhibition that could also reverse anoikis resistance. Transcriptomic analysis revealed that CDK8/19 kinase inhibition induces bidirectional transcriptional …

Rab5c Increases Endothelial Release Of Vwf By Regulating Vesicle Trafficking, Paula Reventun, Pablo Toledano-Sanz, Maria Delgado-Marin, Maria Viskadourou, D Brian Foster, Paul S De Vries, Maria Sabater-Lleal, Nunzio Alcharani, Claudia Gonzalez-Cucharero, William O Osburn, Alanna C Morrison, Alisa S Wolberg, Nicholas L Smith, Marios Arvanitis, Charles J Lowenstein

Faculty, Staff and Student Publications

Background: Abnormal levels of VWF (von Willebrand Factor) are a risk factor for venous thromboembolism (VTE) and bleeding. Genome-wide association studies for VWF have identified novel candidate genes that may regulate VWF levels in humans, including RAB5C (RAS-associated protein RAB5C). We hypothesized that RAB5C regulates VWF release from endothelial cells.

Methods: We studied the effect of RAB5C on vesicle trafficking in human endothelial cells. We performed CRISPR (clustered regularly interspaced short palindromic repeats) interference targeting 2 genetic variants linked to altered VWF levels and evaluated RAB5C expression by reverse transcription-quantitative polymerase chain reaction. We silenced RAB5C or overexpressed RAB5C wild-type, …

Kenyon Collegian - January 15, 2026

The Kenyon Collegian

No abstract provided.

Ultrasonography Of Normal Fetal Kidney Width Measurement For Estimation Of Gestational Age In Sudanese Pregnant Women, Mohamed Omer Mustafa Omer, Mohaned Haleeb Edris, Ali H. Adam, Mohammed A. Abdelmotalab, Hamza Idriss

Iraqi National Journal of Medicine

Background: A precise estimate of gestational age (GA) is essential for providing optimal maternity care and determining the labor date. Aim: This study aimed to determine gestational age between the 14th and 40th weeks for Sudanese pregnant women by measuring the normal fetal kidney width using ultrasound. Methods: The study was designed as a descriptive cross-sectional study in Khartoum and Gezira states, Sudan, from June 2016 to May 2017. Three hundred ninety healthy pregnant women aged between 15 and 45 years were assessed by ultrasound, with overall normal well-being fetuses. Linear regression models for estimating gestational age were developed based …

Evaluation Of D-Dimer Level In Covid-19 Patients, Amal Malik, Noor Kadhim Mohamed-Jawad, Hiba Dawood, Ali Adnan Mohsin

Iraqi National Journal of Medicine

Background: The COVID-19 pandemic is associated with prothrombotic complications, leading to increased morbidity and mortality. D-dimer, a fibrin degradation product, serves as a biomarker for coagulation abnormalities. This study evaluates the role of D-dimer in predicting disease severity and hospitalization in COVID-19 patients. Aim: To assess correlations between D-dimer levels and age, gender, comorbidities, disease severity, and hospitalization needs in COVID-19 patients. Methods: A retrospective analysis of 78 COVID-19-positive patients admitted to an outpatient clinic was conducted. Data on demographics, comorbidities, vaccination status, disease severity, and admission D-dimer levels were analyzed using statistical tests (t-tests, chi-square, Mann-Whitney U). Results: The …

Post-Induction Minimal Residual Disease Study By Flow Cytometry In Pediatric B All And Its Correlation With Initial Clinical And Laboratory Parameters, Huda Ali Alnaseri, Yassmin Ali Alaamiri, Hussam Mahmood Salih

Iraqi National Journal of Medicine

Background: Acute lymphoblastic leukemia (ALL) is a cancer characterized by the rapid and uncontrolled growth of immature lymphoid cells. Among its subtypes, B-lineage ALL in children represents the most frequently diagnosed malignancy in the pediatric population. Despite high survival rates, relapsed or refractory cases remain challenging. Minimal Residual Disease (MRD), detected by flow cytometry, is a strong prognostic marker that guides the intensity of post-induction therapy. Aim: This study aims to evaluate the correlation between post-induction MRD, measured by multicolor flow cytometry, and the initial clinical and laboratory parameters in pediatric patients with B-ALL. Methods: A retrospective cross-sectional study was …

Levels Of 8-Isoprostane And Advanced Oxidation Protein Products In Relation To Sperm Count And Motility, Ahmed Sulaiman, Sherwan Salih

Iraqi National Journal of Medicine

Background: Oxidative stress is implicated in male infertility, with reactive oxygen species contributing to sperm dysfunction. Among oxidative stress markers, 8-isoprostanes (8-isoP) and advanced oxidation protein products (AOPP) serve as indicators of lipid peroxidation and protein oxidation, respectively. However, their relationship with specific sperm abnormalities remains unclear. Aim: This study investigates the oxidative stress markers 8-isoprostane (8-isoP) and advanced oxidation protein products (AOPP) across different semen profiles and explores their correlation with sperm count and motility to evaluate their potential as diagnostic biomarkers in male infertility. Methods: A cross-sectional study was conducted on male partners of infertile couples between May …

Serum Iron Profile In Sudanese Patients Infected By Helicobacter Pylori, Rimaz Gurashi, Abuagla M. Dafalla, Suhair A. Ahmed, Shereen Faisal, Abdelkarim A. Abdrabo

Iraqi National Journal of Medicine

Background: Helicobacter pylori is a Gram-negative, spiral-shaped, motile bacterium that represents one of the most widespread chronic infections in humans, affecting nearly half of the global population. Iron is a vital micronutrient required for almost all living organisms, including H. pylori, which relies on iron to establish colonization. Although several studies have indicated an association between iron deficiency (ID) or iron deficiency anemia (IDA) and H. pylori infection, the precise mechanisms remain incompletely understood. Aim: To assess the serum iron profile among Sudanese patients with H. pylori infection. Methods: Analytical case‑control hospital-based study was conducted at Bahri Hospital, Khartoum state …

Association Of Matricellular Protein, Growth Factor, And Transcription Factor With Molecular Subtypes Of Breast Cancer: A Case Control Study, Marwa Munther Homman, Eman Tariq Ali, Maitham Ali Alrikabi

Iraqi National Journal of Medicine

Background: Breast cancer is a heterogeneous disease comprising molecular subtypes such as Luminal A, Luminal B, Human Epidermal Growth Factor 2 (HER-2)-Enriched, and Triple Negative, each with distinct clinical, molecular, and immunological features. Immunological markers play a critical role in modulating tumor behavior, angiogenesis, and immune evasion. Aim: This study aimed to identify key immunological markers that correlate with the molecular (intrinsic) subtypes of breast cancer and to explore their potential as prognostic factors. Methods: Serum samples from 180 breast cancer patients (56 untreated and 74 treated) were analyzed using Enzyme-Linked Immunosorbent Assay (ELISA) to determine the levels of four …

Writing From The Rift: Queer Temporality And The Refusal Of Resolution, Daniela Ruiz Perez

Masters Theses

This thesis develops a phenomenological method for reading speculative literature as a site where queer ecological temporality is experienced rather than explained. Working with Annihilation (2014) by Jeff VanderMeer, The Day of the Triffids (1951) by John Wyndham, and Undrowned: Black Feminist Lessons from Marine Mammals (2020) by Alexis Pauline Gumbs, the project treats reading as a bodily practice shaped by forms of attention. Texts are not interpreted for stable meaning and instead I remain with moments where resolution is withheld. The work is informed by a Marxist attention to how capitalist time organizes labor, productivity, and value, and how …

Dna Methyltransferase Inhibitors In Hematological Malignancies And Solid Tumors, Valentin Wenger, Guillermo Garcia-Manero, Robert Zeiser, Michael Lübbert

Faculty, Staff and Student Publications

Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5-position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor suppressor genes, oncogenes, and other key regulatory genes. The first-generation DNMTi azacitidine and decitabine have demonstrated substantial efficacy in the treatment of medically non-fit, older patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy (IC), by virtue of their favorable safety profile. Despite these clinical achievements, however, single-agent DNMTi treatment …

Serendipity In Psychiatric Discoveries: Historical Lessons And Future Imperatives For Clinical Observation, Stanley Lyndon, Vineeth P John

Faculty, Staff and Student Publications

Aims and method: Serendipity has driven many of psychiatry's most important treatments, yet contemporary systems may undermine clinicians' ability to notice and develop unexpected therapeutic effects. This selective narrative review synthesises landmark discovery stories, conceptual accounts of serendipity and contemporary case examples to clarify how chance observations become robust advances.

Results: Across historical and modern examples, serendipitous discoveries consistently reflected the interaction of unexpected events with prepared observers working in supportive institutional and research systems. We identify current barriers created by standardised care, funding and trial structures, and professional fragmentation, and outline a multi-level framework for cultivating serendipity through phenomenological …

Bridging Hypoxia And Vision Loss: The Emerging Role Of Connexins In Local And Systemic Eye Diseases, Xianping Zhang, Yalong Cheng, Jean X Jiang, Yuting Li

Faculty, Staff and Student Publications

Hypoxic eye diseases represent a pivotal yet often underappreciated contributor to the onset and progression of many retinal disorders. When hypoxia persists or exceeds the tissue's compensatory capacity, it triggers pathological retinal neovascularization, blood-retinal barrier disruption, and neuronal apoptosis, ultimately resulting in irreversible visual impairment. Connexins (Cxs) form gap junction channels and hemichannels and regulate retinal cell proliferation, differentiation, and survival, thereby playing a central regulatory role in the pathogenesis of hypoxic ocular diseases. In addition to gap junctions, Cx hemichannels promote transmission of molecules between intra- and extracellular environments, further influencing retinal homeostasis under hypoxic stress. This review synthesizes …

Epilepsy Disease Classification: A Community Effort To Enhance The Mondo Disease Ontology, Nicole Vasilevsky, Sarah Gehrke, Kathleen Mullen, Subit Barua, Ian Braun, Tobias Brünger, Curtis Coughlin, Alina Ivaniuk, Daniel Korn, Dennis Lal, Stephanie Marsh, Elaine O'Loughlin, Daniel Olson, Yousif Shwetar, Christalena Sofocleous, Vanessa Vogel-Farley, Heidi Grabenstatter, Melissa Haendel, Christopher Mungall, Sabrina Toro

Faculty, Staff and Student Publications

Motivation: Epilepsy is a diverse group of neurological disorders affecting over 50 million people worldwide. While common epilepsy types are well studied, rare epilepsies-often severe and genetically complex-pose significant challenges in diagnosis, research, and treatment. Accurate and interoperable etiology and disease classifications are critical for improving data sharing, supporting clinical decision-making, and advancing rare disease research.

Results: To enhance the accuracy of epilepsy-related disease concept representation within the Mondo Disease Ontology (Mondo), we conducted a series of expert-driven workshops in collaboration with the team from the Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP). Specialists in epileptology, genetics, neurodevelopment, biomedical …

Desert Plant Endophyte Genome Database: A Curated Repository Of Endophytic Bacterial Genomes Across Arid Ecosystems, Sabiha Parween, Arun Prasanna Nagarajan, Amal K. Alghamdi, Abdul Aziz Eida, Feras F. Lafi, Luma Albanna, Nida Salem, Barakat Abu-Irmaileh, Zaid A. Pirzada, Shahid Siddique, Ruben Garrido-Oter, Paul Schulze-Lefert, Maged M. Saad, Heribert Hirt

All Works

Microbial communities associated with desert plants play a pivotal role in enhancing host survival under extreme environmental stressors, including drought, salinity, and nutrient limitation. The Desert Plant Endophyte Microbial Collection is one of the largest curated repositories of 2500 cultivable endophytic bacteria isolated from 23 native desert plant species across Saudi Arabia, Jordan, and Pakistan. Representing a broad spectrum of arid microhabitats from inland deserts and mountain wadis to coastal mangroves and date palm oases, the collection supports integrative studies on microbial ecology and plant-microbe interactions in water-limited ecosystems. A central component of this initiative is the Desert Plant Endophyte …

Shedding The Chrysalis: Black Women Leading In Higher Education, Olga M. Welch, Carolyn R. Hodges

Navigating Careers in Higher Education Series

Shedding the Chrysalis: Black Women Leading in Higher Education features the voices of six experienced and emerging Black females in a variety of academic leadership roles. This book provides a Black feminist perspective, highlighting the need to address racial realism within higher education administration. These personal testimonies focus on a variety of levels in the academic hierarchy to emphasize the continuum across the lived experiences of these women, some of whom have served in multiple upper-level administrative roles. The contributors’ positions range from postdoctoral research fellows to positions reporting to central administration at predominantly white institutions. Shedding the Chrysalis underscores …

The Disintegration Of Fordism And The Transformation Of Black Anti-Semitism In America, 1945-2005, Mark P. Worrell

Fast Capitalism

No abstract provided.

Torture And Absolution: The Shadow Twin Towers Of Atro/City, Cynthia Haynes

Fast Capitalism

No abstract provided.