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2026

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Research Progress On Construction Strategies And Applications Of Protein-Based Composite Nanodelivery Systems, Xu Xiaojin, Xiong Xiangyuan, Gao Hongxia, Li Ziling Jan 2026

Research Progress On Construction Strategies And Applications Of Protein-Based Composite Nanodelivery Systems, Xu Xiaojin, Xiong Xiangyuan, Gao Hongxia, Li Ziling

Food and Machinery

In recent years, protein-based nanocarriers have attracted widespread attention for their excellent biocompatibility and superior delivery efficiency. However, single protein carriers suffer from some issues, such as high environmental sensitivity, insufficient targeting ability, and poor in vivo circulatory stability. The latest research progress of protein-based nanodelivery systems was analyzed, and common construction strategies were summarized and categorized, such as self-assembly technology, flash nanoprecipitation method, and pH-driven method;the advantages and limitations of different methods in particle size control and encapsulation efficiency were clarified. The coupling mechanisms, preparation methods, and application advantages of the composite systems composed of proteins and polysaccharides, inorganic …

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Research Advances In The Application Of Intelligent Responsive Hydrogels For Controlled Release And Quality Monitoring In Foods, Yin Hongli, Qu Yanfeng, Yang Jiaxing, Yao Jianuo, Li Weize, Liu Shiying Jan 2026

Research Advances In The Application Of Intelligent Responsive Hydrogels For Controlled Release And Quality Monitoring In Foods, Yin Hongli, Qu Yanfeng, Yang Jiaxing, Yao Jianuo, Li Weize, Liu Shiying

Food and Machinery

With the continuously increasing demand for intelligent and precise technologies in the food industry, intelligent responsive hydrogels, as an emerging class of functional materials, have demonstrated great application potential in controlled release and quality monitoring of food products. This article reviews recent research progress in intelligent responsive hydrogels in terms of base material selection and crosslinking methods, types of stimulus responsiveness, and underlying mechanisms. It elaborates on the design and application of intelligent hydrogels in controlled-release systems for food bioactive substances, covering antibacterial packaging, nutrient fortification, and flavor-controlled release. Additionally, the application of intelligent responsive hydrogels in food quality monitoring …

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Research Progress On Effects Of Processing Techniques On Mulberry Leaf Tea Quality, Liang Xiuhua, Ma Huanyan, Zhang Tanjie, Li Lamei, Lin Jie Jan 2026

Research Progress On Effects Of Processing Techniques On Mulberry Leaf Tea Quality, Liang Xiuhua, Ma Huanyan, Zhang Tanjie, Li Lamei, Lin Jie

Food and Machinery

Mulberry leaves serve as important raw materials with both medicinal and edible properties, rich in a variety of nutritional active ingredients. Processed mulberry leaf tea has antioxidant, hypoglycemic, hypolipidemic, anti-inflammatory, and other physiological functions, positioning it as a hot spot of research in the health food sector. Withering, fixation, fermentation, drying, stress treatment, and other processing techniques significantly affect the flavor quality, as well as the types and content of nutritional active ingredients of mulberry leaf tea, thereby affecting the nutritional quality and health benefits of the product. This study focuses on the effects of processing techniques such as withering, …

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Preparation And Characterization Of Nanocellulose-Based Edible Films And Their Fresh-Keeping Effects On Bananas, Tian Huan, Song Zhen, Li Zejun, Sun Yawen Jan 2026

Preparation And Characterization Of Nanocellulose-Based Edible Films And Their Fresh-Keeping Effects On Bananas, Tian Huan, Song Zhen, Li Zejun, Sun Yawen

Food and Machinery

[Objective] To prevent postharvest fruit decay and extend shelf life, a robust, water-resistant, and self-healing multifunctional edible fresh-keeping film was proposed. [Methods] The edible fresh-keeping film's microstructure, chemical structure, physicochemical properties, mechanical properties, and its effects on the shelf life of bananas were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray powder diffractometer (XRD), texture analyzer, and rheometer. [Results] The monomers within the edible film are cross-linked via hydrogen bonds, ester bonds, and electrostatic interactions, forming an irregular network structure on the surface. The film exhibits an elongation at break of 71.73% and a mechanical strength …

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Review Of Bootstrap Applications, Joshua Russell Jan 2026

Review Of Bootstrap Applications, Joshua Russell

Electronic Theses and Dissertations Archive

We investigate the bootstrap methodology and current applications. The bootstrap is a non-parametric resampling method that has universal applicability thanks to the statistical concepts of weak convergence, the law of large numbers, and the central limit theorem. Modern applications of bootstrap methodology have demonstrated time and time again that it is computationally efficient and robust. The earliest days of the bootstrap saw it validated by generating statistics, confidence intervals, and hypothesis tests. It is important to note the universal application and efficiency of the bootstrap, especially when researchers are tempted to utilize the more financially and computationally expensive techniques of …

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January 23, 2026 Ereporter, University Of Alabama At Birmingham Jan 2026

January 23, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

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Caribbean Early Childhood Educators, Primary Educators, And Student Teachers' Perceptions Of Visual Literacy And Visual Images Across The Curriculum, Monica Yvonne Hines-Graham Jan 2026

Caribbean Early Childhood Educators, Primary Educators, And Student Teachers' Perceptions Of Visual Literacy And Visual Images Across The Curriculum, Monica Yvonne Hines-Graham

Walden Dissertations and Doctoral Studies

The problem that was addressed through this study is the gap in knowledge about the integration and evaluation of visual literacy and visual images across the curriculum of early childhood educators, primary educators, and student teachers, despite it being a requirement for teachers in the Caribbean education system. Grounded in Hall and Hord’s concerns-based adoption model, the purpose of this study was to explore the perceptions of early childhood educators, primary educators, and student teachers with the integration and evaluation of visual literacy and visual images across the curriculum. For this basic qualitative design, semistructured interviews with 12 participants from …

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Educating With Chronic Health Conditions During And After A Pandemic: A Narrative Study Of Experiences, Job-Related Stressors, Mental Health, Wellbeing And Coping Strategies Among Black Female Educators, Shawnee Stanfield Blake Jan 2026

Educating With Chronic Health Conditions During And After A Pandemic: A Narrative Study Of Experiences, Job-Related Stressors, Mental Health, Wellbeing And Coping Strategies Among Black Female Educators, Shawnee Stanfield Blake

Student Theses and Dissertations

This qualitative, narrative research study explored the experiences lived by black female educators with chronic health conditions during and after the Covid-19 pandemic in the Southeastern region of the United States. These educators provided continued instruction in a central Jackson, Mississippi school district and a Georgia school district in the central Atlanta metropolitan area. The investigation during this body of work focused on how black female educators with chronic health conditions were impacted both personally and professionally. The research also centered on how these educators employed coping strategies. Candidates endured fear, stress and continued impact on their health. To subject …

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Longfin Mako (Isurus Paucus) Jaw, Nicholas D. Burchett, David W. Kerstetter Jan 2026

Longfin Mako (Isurus Paucus) Jaw, Nicholas D. Burchett, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

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Male Great Hammerhead (Sphyrna Mokarran) Chondrocranium, Michelle W. Bassali, Nicholas D. Burchett, Samuel Escobar, Preston Rice, David W. Kerstetter Jan 2026

Male Great Hammerhead (Sphyrna Mokarran) Chondrocranium, Michelle W. Bassali, Nicholas D. Burchett, Samuel Escobar, Preston Rice, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Male ~10ft Great Hammerhead (Sphyrna mokarran) Chondrocranium

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Sustainability Implications Of Agricultural Practices In The Arkansas Delta: A Field To Market Approach, Melissa Adelle Palumbo Jan 2026

Sustainability Implications Of Agricultural Practices In The Arkansas Delta: A Field To Market Approach, Melissa Adelle Palumbo

Student Theses and Dissertations

The Field-to-Market Fieldprint Calculator is a software tool designed to estimate and compare relative sustainability of differing agricultural practices. This observational research compared conservation techniques to conventional practices in rice and cotton on three separate farms in Northeast Arkansas. Considering management and site conditions, the Fieldprint Calculator was used to compare sustainability metrics to standards at various spatial scales in a spidergraph report. Eight metrics were analyzed to produce reports, including greenhouse gas emissions, water quality and quantity, land and energy use, soil carbon and conservation, and biodiversity. Results showed no significant change in yield between the different production methods, …

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Cotton Production In The Arkansas Delta - A Focus On Water Quality Impacts, Trenton Alexander Barker Jan 2026

Cotton Production In The Arkansas Delta - A Focus On Water Quality Impacts, Trenton Alexander Barker

Student Theses and Dissertations

Farmers in Arkansas irrigate more farmland than 47 other states in the U.S. Agricultural production is a vital contributor to the economy of the state; however, it also contributes heavily to water quantity and quality issues within the Mississippi River Basin and the Gulf of Mexico. Row-crop producers have adopted soil and water conservation practices to mitigate these effects, yet many farmers remain hesitant to adopt conservation methods due to uncertainties about their effects on yield and profits. This thesis evaluates the water quality impacts of conventional and conservation cotton tillage systems under irrigated and rainfed conditions. Runoff, plant development, …

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Direct Solar-Energy Powered Hydrothermal Treatment To Promote Biomethane Production From Anaerobic Digestion Of Rice Processing Waste, Kainat Rahnuma Jan 2026

Direct Solar-Energy Powered Hydrothermal Treatment To Promote Biomethane Production From Anaerobic Digestion Of Rice Processing Waste, Kainat Rahnuma

Student Theses and Dissertations

Hydrolysis is a slow and energy-intensive process and a rate-limiting step in anaerobic digestion (AD). This research investigates performance strategies for integrating hydrothermal treatment (HT) with AD. HT-AD systems were less economically viable than AD-only options because of the high energy consumption of HT. Therefore, we used solar energy to conduct HT via either solar cookers or solar panels. The HT method significantly improved digestion performance, reducing the lag phase from 60 to 24 h, and increasing overall yield. Hydrothermally treated rice, rice bran, and rice hulls produced 22,932 mL, 13,136 mL, and 1283 mL, respectively. However, untreated rice, rice …

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Stories From Former Foster Youth College Graduates: The Positive Impact Of K-12 Schooling And Related Educational Policy, Amanda Moon, Kristen D. Seay Jan 2026

Stories From Former Foster Youth College Graduates: The Positive Impact Of K-12 Schooling And Related Educational Policy, Amanda Moon, Kristen D. Seay

Faculty and Staff Publications

Youth in foster care face disproportionate challenges when it comes to education and personal well-being. Many studies use a deficit lens when evaluating these challenges. In contrast, this study is asset-based, centering first-person accounts from five former foster youth college graduates. Using a counter-narrative framework, we conducted semi-structured interviews with participants to reveal key supports in K-12 schooling participants believed helped them achieve academic and life milestones. These were relationships with teachers and coaches, access to extracurricular activities, and literacy-rich environments. We also reviewed 11 relevant federal educational policies to identify provisions and implementation needs that aligned with participant experiences. …

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A Universal Of Human Social Cognition: Children From 17 Communities Process Gaze In Similar Ways, Manuel Bohn, Julia Christin Prein, Agnes Ayikoru, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Joan Isabella, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Katie Slocombe, Robert Z. Sparks, Jahnavi Sunderarajan, Wilson Vieira, Zhen Zhang, Yufei Zong, Roman Stengelin, Daniel B.M. Haun Jan 2026

A Universal Of Human Social Cognition: Children From 17 Communities Process Gaze In Similar Ways, Manuel Bohn, Julia Christin Prein, Agnes Ayikoru, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Joan Isabella, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Katie Slocombe, Robert Z. Sparks, Jahnavi Sunderarajan, Wilson Vieira, Zhen Zhang, Yufei Zong, Roman Stengelin, Daniel B.M. Haun

School of Psychology

Theoretical accounts typically assume that key features of human socio-cognitive development are universal. This paper reports a large-scale cross-cultural study (17 communities, diverse ethnicities, N = 1,377, 709 female, mean = 5.50 years, -collected March 2022 to January 2024) on gaze following in early childhood. To test for universality, cognitive processing signatures were derived from a computational model treating gaze following as social vector estimation. Results showed substantial variation between communities and individuals. Yet, the processing signature was found in all communities. Individual differences in performance were related to children's familiarity with the data-collection device but not opportunities for social …

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Communication Disorders Graduate Student: Perspective Of Voice, Maycie Brentney Terrell / Blankenship Jan 2026

Communication Disorders Graduate Student: Perspective Of Voice, Maycie Brentney Terrell / Blankenship

Student Theses and Dissertations

This study examined the influence of training in SPEAK OUT!® on the perceptual ratings of voice and speech made by communication disorders (CD) graduate students. The purpose of this study was to investigate the influence of SPEAK OUT!® training by comparing those who have undergone SPEAK OUT!® training with those who have not. To address this, 36 participants who attend communication disorders graduate programs within the United States were recruited. Data were collected through a Qualtrics survey distributed via email and analyzed using the Statistical Package for the Social Sciences (SPSS). The findings indicate that perceptual ratings across most voice …

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Investigating The Challenges That Black Female Superintendents Face While Navigating Local School Boards, Eric Dailey Jan 2026

Investigating The Challenges That Black Female Superintendents Face While Navigating Local School Boards, Eric Dailey

Student Theses and Dissertations

For the past twenty years, Black women have increasingly ascended to the role of school district superintendent. Black female superintendents navigate education systems that were not built with them in mind creating unique challenges. The purpose of this qualitative phenomenological study was to investigate the challenges that Black female superintendents face while navigating local school boards. This study was informed by glass ceiling theory, gendered organizations theory, and a black feminist framework establishing a research base for this study’s focus. Eight Black female superintendents were interviewed using an interview protocol. This study reveals that Black female superintendents experience similar challenges …

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High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann Jan 2026

High-Throughput Screens Identify Genotype-Specific Therapeutics For Channelopathies, Christian L. Egly, Alex Shen, Tri Q. Do, Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo, Matthew Ku, Brian P. Delisle, Brett M. Kroncke, Björn C. Knollmann

Physiology Faculty Publications

Genetic diseases such as ion channelopathies substantially burden human health. Existing treatments are limited and not genotype specific. Here, we report a 2-step high-throughput approach to rapidly identify drug candidates for repurposing as genotype-specific therapy. We first screened 1,680 medicines using a thallium-flux trafficking assay against Kv11.1 gene variants causing long QT syndrome (LQTS), an ion channelopathy associated with fatal cardiac arrhythmia. We identified evacetrapib as a suitable drug candidate that improves membrane trafficking and activates channels. We then used deep mutational scanning to prospectively identify all Kv11.1 missense variants in an LQTS hotspot region responsive to treatment with evacetrapib. …

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Extraction Process Optimization Of Black Ginseng Polysaccharides By Compound Enzymes, Liu Xin, Xu Duoduo, Qiu Chaonan, Fan Bo, Hou Xiangzhu, Zhang Huijia, Gao Yang Jan 2026

Extraction Process Optimization Of Black Ginseng Polysaccharides By Compound Enzymes, Liu Xin, Xu Duoduo, Qiu Chaonan, Fan Bo, Hou Xiangzhu, Zhang Huijia, Gao Yang

Food and Machinery

[Objective] To optimize the extraction process of black ginseng polysaccharides (BGP) by an enzyme extraction method, and to investigate the antioxidant activity of BGP. [Methods] The optimal dosage of compound enzymes for BGP extraction is obtained using the orthogonal method, and the process conditions for BGP extraction by compound enzymes are optimized using the response surface method. The in vitro antioxidant activity of BGP is evaluated using the DPPH and the ABTS+ radical methods. [Results] The optimal enzyme ratio is 120 mg cellulase, 120 mg pectinase, and 80 mg papain. The optimal enzymatic hydrolysis process conditions are an enzymatic digestion …

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Community And Individual Risk Factors Associated With Tuberculosis Treatment Outcomes: Ca, Md, And Oh, [2017-2021]., Kadiatu Banjoko Jan 2026

Community And Individual Risk Factors Associated With Tuberculosis Treatment Outcomes: Ca, Md, And Oh, [2017-2021]., Kadiatu Banjoko

Walden Dissertations and Doctoral Studies

There are unsuccessful treatment outcomes with Tuberculosis (TB) disease, although effective therapies exist. This study aimed to identify predictors of unsuccessful treatment using the socioecological model. A quantitative cross-sectional study and multinomial logistic regression analysis were used to measure the associations between long-term care (LTC), homelessness, correctional facility, Human Immunodeficiency Virus (HIV), diabetes, excess alcohol, illicit drug use, and TB treatment outcomes of death, lost to follow-up, and treatment refusal. The sample consisted of 7,589 individuals aged 15 and older with pulmonary TB between 2017 and 2021, residing in California, Ohio, and Maryland. Findings indicated a correlation between community factors …

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Ai-Assisted Qualitative Analysis Of Formative Feedback To Support Student-Centered Learning In Physiology, Sulekha Anand, Ursula Holzmann, Alexander Y. Payumo Jan 2026

Ai-Assisted Qualitative Analysis Of Formative Feedback To Support Student-Centered Learning In Physiology, Sulekha Anand, Ursula Holzmann, Alexander Y. Payumo

Faculty Research, Scholarly, and Creative Activity

This study evaluates the effectiveness of large language models (LLMs), specifically Claude Sonnet 4.0 and ChatGPT 4.1, for analyzing formative feedback to support student-centered learning (SCL). In large courses, instructors often struggle to promptly review and synthesize student input. We used a low-stakes task: analyzing 63 anonymous student responses to a Muddiest Point prompt in a human physiology class after a lecture on respiratory physiology. Across 20 runs, both LLMs consistently identified "Ventilation and Lung Mechanics" as the most frequent area of confusion, aligning with human analysis. LLMs completed the task significantly faster than a human reviewer (average: 19.6 s/31.0 …

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Restoration Enhances Carbon Storage In Mangroves After Hurricane Impacts, Robert Puschendorf Jan 2026

Restoration Enhances Carbon Storage In Mangroves After Hurricane Impacts, Robert Puschendorf

School of Biological and Marine Sciences

Mangroves are globally important blue-carbon ecosystems, yet their resilience isthreatened by extreme weather events and hydrological alterations. Insoutheastern Mexico, a large mangrove die-off occurred in 1995 followingHurricane Roxanne and Tropical Storm Opal, linked to storm-surge–drivenhypersalinity, sedimentation, and prolonged flooding. In 2005, an ecologicalrestoration program was launched in the Términos Lagoon region, focusing onhydrological rehabilitation and reforestation with Avicennia germinans. Fourteenyears later, we assessed ecosystem recovery by quantifying total ecosystemcarbon stocks (TECS), defined as the sum of 0–50-cm soil organic carbon andtree biomass carbon, across conserved, degraded, and restored sites, and byreconstructing vegetation cover dynamics from multi-decadal satellite imagery(1984–2023). TECS differed …

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Intestinal Epithelial Tlr5 Signaling Promotes Barrier-Supportive Macrophages, Ming-Ting Tsai, Ryann Callaghan, Charles Ng, Lisette Peres-Tintin, Dean B Matthews, Nikketa Stanford, Karuna Ganesh, Mary K Estes, Gretchen E Diehl Jan 2026

Intestinal Epithelial Tlr5 Signaling Promotes Barrier-Supportive Macrophages, Ming-Ting Tsai, Ryann Callaghan, Charles Ng, Lisette Peres-Tintin, Dean B Matthews, Nikketa Stanford, Karuna Ganesh, Mary K Estes, Gretchen E Diehl

Faculty, Staff and Students Publications

Intestinal macrophages are essential for epithelial barrier repair. In homeostasis, macrophages are continuously replenished by recruitment of circulating CCR2+ monocytes into the intestinal lamina propria. This requires the commensal microbiota, however, the specific microbial factors and downstream host pathways that coordinate macrophage replenishment are inadequately understood. Here, we show that colonization with an E. coli isolate increased CCR2+ macrophages in the intestine and ameliorated pathology in a colitis model. Using human colonic organoids, we showed E. coli colonization induced CCL2 secretion by intestinal epithelial stem cells which promoted monocyte migration. In vivo, protection was abolished in the absence of epithelial …

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Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin Jan 2026

Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin

Faculty, Staff and Students Publications

Adult mammalian hearts exhibit limited regenerative capacity because of the restricted renewal of cardiomyocytes. Recent studies reveal that mammalian hearts exhibit transient regenerative potential within a short time frame after birth, suggesting a regulatory mechanism that prevents adult hearts from initiating a regenerative response to cardiac injury. Here, we discovered that an active form of YAP, named YAP6SA, which is not inhibited by the Hippo signaling pathway and does not interact with TEADs, induces cardiomyocyte cell cycle reentry. In addition, YAP6SA interacts with scaffold protein MPDZ to regulate Rho GTPases and promote cell cycle progression in cardiomyocytes (CMs). Importantly, YAP6SA …

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De Novo Variants In The Splicing Factor Gene Sf3b1 Are Associated With Neurodevelopmental Disorders, Kevin Uguen, Tiffany Bergot, Marie-Pier Scott-Boyer, Solène Chapalain, Camille Desdouets, Séverine Commet, Changlian Zhu, Yiran Xu, Yangong Wang, Tony Roscioli, Frederic Tran-Mau-Them, Laurence Faivre, Julien Maraval, Julian Delanne, Anne-Sophie Denommé-Pichon, Antonio Vitobello, Céline Jost, Marc Planes, Susan Hiatt, Patricia Wheeler, Claudia Gonzaga-Jauregui, Heng Wang, Baozhong Xin, Valerie Sency, Michael C Kruer, Somayeh Bakhtiari, Patrick Sulem, Cynthia Curry, Trine Prescott, Gertrud Strobl-Wildemann, Theresa Brunet, Martine Doco Fenzy, Thomas Courtin, Céline Poirsier, Trine Bjørg Hammer, Christina D Fenger, Melissa Macpherson, Kosuke Izumi, Jacqueline Leonard, Dong Li, Elaine H Zackai, Ian A Glass, Scott Ward, Philippe M Campeau, Maria Carla Hermida Borroto, Laurence Le Moigno, Hilde Van Esch, Liesbeth De Waele, Daniel G Calame, James R Lupski, Giulia Barcia, Cristina Peduto, Pauline Planté-Bordeneuve, Lucie Dupuis, Roberto Mendoza-Londono, Dimitri J Stavropoulos, Jennifer Gillibert-Duplantier, Thomas Besnard, Laura Do Souto Ferreira, Benjamin Cogné, Stéphane Bézieau, Arnaud Droit, Laurent Corcos, Eric Lippert, Claude Férec, Sebastien Küry, Delphine G Bernard Jan 2026

De Novo Variants In The Splicing Factor Gene Sf3b1 Are Associated With Neurodevelopmental Disorders, Kevin Uguen, Tiffany Bergot, Marie-Pier Scott-Boyer, Solène Chapalain, Camille Desdouets, Séverine Commet, Changlian Zhu, Yiran Xu, Yangong Wang, Tony Roscioli, Frederic Tran-Mau-Them, Laurence Faivre, Julien Maraval, Julian Delanne, Anne-Sophie Denommé-Pichon, Antonio Vitobello, Céline Jost, Marc Planes, Susan Hiatt, Patricia Wheeler, Claudia Gonzaga-Jauregui, Heng Wang, Baozhong Xin, Valerie Sency, Michael C Kruer, Somayeh Bakhtiari, Patrick Sulem, Cynthia Curry, Trine Prescott, Gertrud Strobl-Wildemann, Theresa Brunet, Martine Doco Fenzy, Thomas Courtin, Céline Poirsier, Trine Bjørg Hammer, Christina D Fenger, Melissa Macpherson, Kosuke Izumi, Jacqueline Leonard, Dong Li, Elaine H Zackai, Ian A Glass, Scott Ward, Philippe M Campeau, Maria Carla Hermida Borroto, Laurence Le Moigno, Hilde Van Esch, Liesbeth De Waele, Daniel G Calame, James R Lupski, Giulia Barcia, Cristina Peduto, Pauline Planté-Bordeneuve, Lucie Dupuis, Roberto Mendoza-Londono, Dimitri J Stavropoulos, Jennifer Gillibert-Duplantier, Thomas Besnard, Laura Do Souto Ferreira, Benjamin Cogné, Stéphane Bézieau, Arnaud Droit, Laurent Corcos, Eric Lippert, Claude Férec, Sebastien Küry, Delphine G Bernard

Faculty, Staff and Students Publications

SF3B1 is an essential and ubiquitous splicing factor that plays a pivotal role in the early steps of pre-mRNA splicing. Recurrent somatic missense mutations in SF3B1 are frequent in cancers, but no constitutional variant has been reported so far. We describe here a cohort of 26 individuals with neurodevelopmental disorders, harbouring SF3B1 constitutional heterozygous variants that appeared mostly de novo. Patients present with a global developmental delay, associated with variable neurological and facial dysmorphic traits. A dichotomy may emerge between patients harbouring predicted loss of function (n = 9) and missense variants (n = 17), the latter being associated with …

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Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer Jan 2026

Scaling Pedestrian Crossing Analysis To 100 U.S. Cities Via Ai-Based Segmentation Of Satellite Imagery, Marcel E. Moran, Arunav Gupta, Jiali Qian, Debra Laefer

Faculty Research, Scholarly, and Creative Activity

Accurately measuring street dimensions is essential to evaluating how their design influences both travel behavior and safety. However, gathering street-level information at city-scale with precision is difficult given the quantity and complexity of urban intersections. To address this challenge in the context of pedestrian crossings — a crucial component of walkability — we introduce a scalable and accurate method for automatically measuring crossing distance at both marked and unmarked crosswalks, applied to America’s 100 largest cities. First, OpenStreetMap coordinates were used to retrieve satellite imagery of intersections throughout each city — totaling roughly three million images. Next, Meta’s Segment Anything …

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Nighttime Or Daytime? How Milk Melatonin Levels Relate To Differential And Somatic Cell Count In Dairy Cow Milk, Eleonora Dall'olio, Claudio Cipolat-Gotet, Melania Andrani, Valeria Cavalli, Giovanni Ferri, Mario Baratta, Roberta Saleri, Fabio De Rensis Jan 2026

Nighttime Or Daytime? How Milk Melatonin Levels Relate To Differential And Somatic Cell Count In Dairy Cow Milk, Eleonora Dall'olio, Claudio Cipolat-Gotet, Melania Andrani, Valeria Cavalli, Giovanni Ferri, Mario Baratta, Roberta Saleri, Fabio De Rensis

The Thai Journal of Veterinary Medicine

This study investigates the impact of winter nighttime versus daytime milking on melatonin concentration in milk and explores its relationship with somatic cell count (SCC) and differential somatic cell count (DSCC). Milk samples were collected from 40 Holstein cows at 12-hour intervals (04:00 AM Night samples and 04:00 PM Day samples) during the winter season (11 h of light and 13 h of darkness). The relationship between melatonin content, SCC and DSCC was assessed. Night milk had significantly higher melatonin levels (15.63 ± 1.90 pg/mL) compared to day milk (6.80 ± 0.75 pg/mL). SCC was significantly lower in night milk …

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Effect Of Dietary Chitosan Oligosaccharide Levels And Molecular Weight With Deacetylation Degree Characteristics On Peptide Transporter 1 Gene Expression In Weaning Pig’S Small Intestine, Boonrit Thongsong, Sarinee Kalandakanond-Thongsong, Rath Pichyangkura Jan 2026

Effect Of Dietary Chitosan Oligosaccharide Levels And Molecular Weight With Deacetylation Degree Characteristics On Peptide Transporter 1 Gene Expression In Weaning Pig’S Small Intestine, Boonrit Thongsong, Sarinee Kalandakanond-Thongsong, Rath Pichyangkura

The Thai Journal of Veterinary Medicine

The present study aimed to assess the expression response of peptide transporter1 (PepT1) mRNA (SLC15A1) in weaning pig’s small intestine to the effect of dietary chitosan oligosaccharide (COS) supplement level, molecular weight (MW) and deacetylation degree (DD) characteristics. On days 28 and 56 of the experiments, small intestine samples obtained from our previous two experiments on weaned pigs were used to study the PepT1 mRNA expression. In experiment 1, pigs received either a basal diet or a basal diet supplemented with 75, 150, or 225 mg/kg COS. In experiment 2, pigs received either a basal diet or a basal diet …

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Collaboration Of Economic Institutions Based On Empowerment Programs To Strengthen Food Security: The Case Of Laying Hens In North Gorontalo, Karin Safitri Jan 2026

Collaboration Of Economic Institutions Based On Empowerment Programs To Strengthen Food Security: The Case Of Laying Hens In North Gorontalo, Karin Safitri

Jurnal Administrasi Bisnis Terapan

This study analyzes the role of economic institutional cooperation in strengthening food security through the development of laying hen farming in North Gorontalo Regency. Eggs are positioned as a strategic animal food due to their nutrient density and affordability for households, while also being relevant to the agenda of improving nutritional status through government programs. This study examines how the synergy of village and community institutions (e.g., Village-Owned Enterprises, cooperatives, and livestock groups) with regional livestock empowerment programs (e.g., the 2 Goats 10 Chickens/G2-10 Movement) and the national Free Nutritious Meals (MBG) program can strengthen production capacity, expand the farmer …

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2020u_Uc02_Approved_Pm_Bs-Interdisciplinary-Studies-Curriculum-Changes-Revision1, Undergraduate Curriculum Council Jan 2026

2020u_Uc02_Approved_Pm_Bs-Interdisciplinary-Studies-Curriculum-Changes-Revision1, Undergraduate Curriculum Council

All Approved Curriculum

No abstract provided.

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