Digital Commons Network^™

Racing To Safety: Tax Policy For Ai Safety-By-Design, Mirit Eyal, Yonathan Arbel

Articles

The White House recently announced its vision of artificial intelligence (AI) policy: AI development is a race and America must win it. To that end, a new America's AI Action Plan directs federal agencies and states to remove regulatory barriers to AI development and accelerate innovation. This approach leaves limited room for regulatory measures that would address the safety risks of powerful AI systems: their behavior in novel domains remains unpredictable, their decision-making opaqueness, and their alignment with human values is uncertain. While experts warn of large-scale accidents, policymakers find themselves in a bind: Regulate AI and cede ground to …

Sampling And Counting Graph Structures With Triangle Motifs, Sherry Robinson

Theses

Understanding the structure of real-world networks often relies on identifying significant (i.e., occurring significantly more frequently than random) subgraph patterns, or motifs, such as triangles. To assess their significance, null models generate random samples from a constrained distribution of graphs, preserving selected properties while randomizing others. These models may either generate random graphs or sample structures from a fixed input graph. This thesis focuses on the latter, specifically the problem of sampling and counting graph structures that incorporate triangle motifs. While efficient algorithms exist for sampling classical structures such as matchings, extending these methods to higher-order motifs remains an important …

Avoiding Misleading Estimates Of Among-Individual Variance Caused By Non-Random Sampling Of Individuals In A Changeable Environment, Denis Réale, Hassen Allegue, Yimen G. Araya-Ajoy, Ned A. Dochtermann, Shinichi Nakagawa, Joel L. Pick, Holger Schielzeth, David F. Westneat, Niels J. Dingemanse

Biology Faculty Publications

Animal ecologists frequently quantify variance in hierarchically structured traits in wild populations. Importantly, phenotypic plasticity within the period of measurement can modify the trait of interest in response to various unmeasured, temporally or spatially changeable, environmental conditions. Non-random sampling among units of the random effect (e.g. individuals) regarding the environment at issue may lead to estimates of the variance among ((Formula presented.)) or within ((Formula presented.)) such units that conflate several types of processes. This mixing of underlying biology can affect interpretations of the random effect variance. Here, we explore the conditions leading to this situation and assess potential solutions …

How Wasteful Is Signaling?, Alex Frankel, Navin Kartik

Cowles Foundation Discussion Papers

Signaling is wasteful. But how wasteful? We study the fraction of surplus dissipated in a separating equilibrium. For isoelastic environments, this waste ratio has a simple formula: β/(β + σ), where β is the benefit elasticity (reward to higher perception) and σ is the elasticity of higher types’ relative cost advantage. The ratio is constant across types and is independent of other parameters, including convexity of cost in the signal. We show that the directional effects of β and σ on waste extend to non-isoelastic environments.

Toward A Neuroleadership Framework, Bryan G. Wood

PhD in Organizational Leadership

Neuroleadership is an emerging field that seeks to connect neural mechanisms, psychological processes, and leadership behaviors within organizational contexts. Despite continued scholarly interest, the literature remains conceptually fragmented and lacks a coherent framework for organizing its recurring themes and constructs. The purpose of this study was to develop a conceptual framework for neuroleadership through a quantitative analysis of records retrieved from the PsycINFO database and interpreted through qualitative synthesis. The findings revealed recurring themes related to core leadership processes, applied contexts, and associated outcomes while also indicating thematic convergence without full conceptual integration across the field. These patterns were organized …

An Evidence-Based Educational Intervention To Enhance Nurses' Knowledge Of Metabolic Syndrome In Residential Care Facilities, Marie Tanyi

Doctor of Nursing Practice Scholarly Projects

The project addresses a critical gap in nursing education by implementing a structured, evidencebased educational intervention led by an Advanced Practice Registered Nurse (APRN) to improve nurses’ knowledge of metabolic syndrome in residential care facilities. The purpose was to determine whether this intervention could significantly enhance nurses’ understanding and management of metabolic syndrome, a complex cluster of disorders present in adult populations. Nine nurses participated in targeted educational sessions focusing on definition, diagnosis, complications, and evidence-based prevention and management strategies. Each participant completed the Metabolic Syndrome Knowledge Scale (MSKS) questionnaire before and after the intervention to assess changes in knowledge. …

Corporate Fiduciary Duties And The Climate And Biodiversity Crisis, Eric W. Orts, Sandra G. Schafhäutle

Michigan Journal of Environmental & Administrative Law

This Article argues that addressing one of the most urgent environmental challenges facing humanity today—the global climate and biodiversity crisis—calls for a transformation at the heart of corporate law: its fiduciary duties. After demonstrating how current corporate fiduciary duties are implicated in this crisis, we argue for reform of fiduciary duties operating at two levels: those governing directors and officers of business corporations, and those governing institutional investors and asset managers. We then distinguish between two general kinds of corporate fiduciary duties: permissive and mandatory. We contend that corporate law should accommodate a more expansive understanding of fiduciary duties by …

Four Decades, No Progress: Time For A Columbia River Basin Compact, Liesl L. Bogaard

Michigan Journal of Environmental & Administrative Law

Since the Power Act’s passage in 1980, the government entities who develop and implement energy policy in the Pacific Northwest have operated under a congressional mandate to protect fish and wildlife in the Columbia River Basin. However, nearly half a century later, the number of wild salmon and steelhead returning to their native spawning grounds is still in decline, largely due to dam operations in the Columbia and its tributaries. This Note examines the history of hydroelectric power generation in the Columbia River Basin and its impact on fish populations, drawing parallels between the environmental crisis in the Columbia River …

Owning Geothermal Energy, Gabriel Eckstein

Michigan Journal of Environmental & Administrative Law

Geothermal energy holds vast potential for decarbonizing the U.S. energy system, yet the sector remains significantly underdeveloped, supplying only 0.4% of the nation's electricity. A principal barrier to growth is the fragmented and ambiguous legal landscape currently governing ownership of geothermal resources: thirty-three states lack any clear statutory or common-law framework identifying who owns subsurface thermal energy. This Article examines the physical characteristics of geothermal energy, recent developments in the U.S. geothermal sector, and the principal doctrinal approaches that might govern ownership of subsurface heat, including the ad coelum doctrine, common-pool and open-access frameworks, the rule of capture, and public …

Strategies And Techniques In Early Childhood Education, Abigail Strutzenberg

Master's Theses & Capstone Projects

As early childhood education shifts toward high-stakes accountability, the traditional "bridge year" of age four is increasingly dominated by "drill-and-kill" academic instruction. This project investigates the growing tension between rigorous academic standards and developmentally appropriate practices. The study explores how the implementation of intentional, play-based strategies—specifically guided play and multisensory scaffolding—can meet mandatory benchmarks for phonemic awareness and self-regulation without compromising a child’s social-emotional well-being. Ultimately, the research seeks to identify how educators can reclaim their pedagogical autonomy by balancing state mandates with the intrinsic needs of the developing child. The central thesis argues that when academic content is embedded …

Library News April 2026, Research Medical Library

Library News 2026

• Measuring Impact: How the RML Supported High-Quality Scientific Publishing in 2025
• Names, Logos, and Seals Through the Years
• Recent Published Books from UT MD Anderson Authors and Editors
• In What Instances Should You Use “Instance” and “Incidence”?

Effects Of Tubulin-Binding Medications On Microplastic Uptake And Cyotoskeletal Functionality Across Diverse Cell Types, Alejandra D. Favela Santos

Posters - 2026

• Microtubules are composed of of a- and b- tubulin heterodimers, vital for cell structure, shape, and intracellular transport • Microtubules are also useful as they separate chromosomes during cell division • Microplastics (< 5 mm) are considered a health threat and have been found throughout the whole body (1) o In several studies, microplastics have been correlated to higher rates cardiorespiratory issues, endocrine disruption, and cancer (1) • Tubulin-binding medications are widely used as chemotherapeutic agents as they are known for disrupting cell division and targeting tubulin (2,3) o In this study, these medications were used to determine whether microtubules play a role in microplastic uptake § Colchicine typically binds to tubulins and arrests polymerization and growth § Nocodazole disrupts polymerization and prevents spindle formation § Vinblastine inhibits microtubule assembly and disruptions miotic spindle formation.

• The purpose of this study was to determine if different concentrations of tubulin-binding medications affect microplastic uptake o C2C12, RAW 264.7, and MOVAS cell lines were used to evaluate whether these changes are cell type specific 

If microtubule dynamics are disrupted, microplastic uptake can be affect in a concentration-dependent and cell type- specific manner.

Research Showcase Program, St. Mary's University

Program - 2026

No abstract provided.

Development Of A Dendritic Cell Model To Unravel The Secrets Of Cards Toxin, Lizbeth Gomez

Posters - 2026

Dendritic cells (DCs) are derived from hematopoietic stem cells of the bone marrow. They are the most efficient antigen presenting cell, presenting antigens to T cells to initiate clonal expansion and differentiation of the T cells into memory and effector cells. Thus, activating the effector functions of T cells in cell-mediated and humoral immune responses (2). Community-acquired respiratory distress syndrome (CARDS) toxin is produced by Mycoplasma pneumoniae that causes acute and chronic lung infections (4). Dendritic cells play a key role in the immune response to respiratory mycoplasmas (3). However, the mechanism underlying in DC and CARDS toxin interactions are …

Signaling Response Of Epinephrine Treated Cards Toxin-Infected Thp-1 Macrophages, Trinity Martinez

Posters - 2026

Aspiration pneumonia is a common mild case of pneumonia, a disease where the lungs are inflamed and filled with fluid, compromising respiration and gas exchange. One common cause of mild pneumonia is bacterial infection via a pathogen known as Mycoplasma pneumoniae. M. pneumoniae causes a variety of respiratory illness- ranging from pharyngitis, tracheobronchitis, mild pneumonia- and in rare cases encephalitis. M. pneumoniae produces the CARDS toxin, which participates in ADP-ribosylation and vacuolization (Kannan et al., 2006)1. The CARDS toxin causes aspiration pneumonia by paralyzing the cilia that lines the respiratory tract. Epinephrine, or Adrenaline- is a hormone that is medically …

G-Quadruplex Dna-Driven Genomic Instability Under Ber Loss, Addison Belick, Claryssa Gutierrez, Joslynn Rosas, Andrea Vargas

Posters - 2026

Base Excision Repair (BER) is a cellular tool that can repair damaged DNA (Hindi et al., 2022, Cellular and Molecular Life Sciences). G-quadruplexes (G4s) are unique 4-stranded structures in DNA or RNA that are rich in guanine (Gray et al., 2023, Nat. Chem. Biol). The purpose of this study is to understand whether BER contributes to the removal of G4s in DNA. This will determine if the BER-deficient yeast is more sensitive to treatment with G4-binding drugs than the BER-proficient yeast. We will replace the APN1 gene in the yeast genome with the URA3 gene, because the wild type yeast …

Effects Of Mycoplasma Pneumoniae Cards Toxin On Lung Fibroblast Function, Shuri Magdalene

Posters - 2026

Mycoplasma pneumoniae is a common respiratory pathogen whose virulence depends largely on the community-acquired respiratory distress syndrome (CARDS) toxin, a 591-amino-acid ADP-ribosylating protein¹. CARDS toxin induces immune responses²˒³, causes vacuolation in lung epithelial cells, and contributes to the inflammatory and pathological features of pneumonia. IMR-90 fibroblasts. IMR-90 cells are human fetal lung fibroblasts widely used to study responses to inflammatory signals, extracellular matrix production, and lung injury or repair. Rationale. Fibroblasts are key drivers of tissue remodeling and fibrosis during lung injury. Defining how CARDS toxin influences fibroblast programs in inflammation, cell-cycle control, and matrix remodeling²˒³ will clarify how M. …

Evaluating The Effects Of Akt Knockdown And Everolimus Treatment On Ewing Sarcoma, Arisha Arif, Alfie Barcenez, Nicole Vanegas-Riddick

Posters - 2026

The purpose of this study is to use the gene AKT1, due to the interest in AKT1’s role in cancer cell proliferation, and the drug Everolimus, to determine if combined targeted therapy works as a more efficient therapeutic approach. We hypothesize that the knockdown of AKT1 will increase the sensitivity of Ewing sarcoma cells to Everolimus, resulting in reduced proliferation and/or survival compared to drug treatment alone. This would suggest that AKT1 normally protects cells from drug-induced stress. Ewing Sarcoma has been connected to chromosomal translocations and most common in pediatric patients. It is most often treated with chemotherapy and …

Impact Of Ashwagandha Treatment On Cytokine Production And Macrophage Differentiation Into Thp-1 Cells, Betsi Diaz Chavarin, Aditi Kumar

Posters - 2026

Inflammation is a critical biological response that enables the immune system to react to infections, injuries, or stressful situations. However, chronic or excessive inflammation can lead to tissue damage and contribute to a wide range of diseases, including neurodegenerative disorders, metabolic syndromes, and immune dysregulation. 3,4 Interleukin-1 beta (IL-1β) is a key pro-inflammatory cytokine that plays a central role in initiating and amplifying the immune response. 1,2 It is primarily produced by activated monocytes and macrophages in response to stimuli such as pathogens or stress signals. In addition, IL-1β acts on the hypothalamus to induce fever, which creates an environment …

Sirna Knockdown Of Rptor Alters Gene Expression In Ewing Sarcoma Cells, Sergio Cipriano, David Leavitt, Michael Oliva, Liam Valdez

Posters - 2026

Ewing sarcoma is a highly aggressive cancer that primarily affects children and young adults. Although treatment options exist, many patients do not respond effectively, showing the need for improved targeted therapies¹. RPTOR is a key in mTORC1 complex which regulates cell growth, proliferation, and survival². LY2874455 is a selective pan-FGFR inhibitor that targets growth factor signaling pathways involved in tumor progression³, and FGFR signaling interacts with pathways such as mTOR, making it a potential target for combination therapies. We hypothesized that silencing RPTOR in Ewing sarcoma cells would disrupt mTOR signaling and alter expression of genes linked to cell survival …

Take A Hit? Take A Hit: Quantifying Cell Death In E-Cigarette Exposed Bronchial Epithelial Cells Following Cards Toxin Treatment, Truman Havrda, Hannah Jiron, Sierra Trevino

Posters - 2026

The rapid rise of e-cigarette use among young adults has created a significant public health challenge, as the popularity of "vaping" has grown faster than our understanding of its long term cellular consequences. Current research indicates that e-cigarette vapor (ECV) induce high levels of oxidative stress and impair the lungs' ability to clear bacterial pathogens. Furthermore, ECV exposure upregulates specific receptors on the surface of airway cells, essentially making it easier for bacteria to adhere to and infect the lungs. While we know that both e-liquids and vapor trigger inflammatory responses and cytotoxicity, there is limited data on how these …

Between Boots And Beaches: A Study Of Spanglish Across The Souothwest, Payton Mayfield, Kaylynn Perez, Demetri Zoutis, Sandra Villarreal

Posters - 2026

When two living organisms reproduce, they create new life—an entity that is distinct, yet traceable to its origins through inherited traits. While languages are not biological, a similar process of creation can occur through contact and convergence. When two languages interact, a new vernacular may emerge, shaped by its linguistic “parentage” while developing its own structures, meanings, and cultural significance. Spanglish represents one such linguistic evolution. This study examines the development of Spanglish across the United States mid-West, with a focus on communities spanning from Texas to California. By comparing these regions, the research identifies both shared patterns and regional …

Does Social Grouping Influence Object Play By Belugas?, Javier Obiltas, Phillip Clayton

Posters - 2026

Play is defined as voluntary behavior that differs from functional behaviors and typically occurs in low-stress environments. In cetaceans, object play has been linked to development, motor skill practice, and social learning. Play behavior is an important factor of development in belugas, because belugas are social animals that live and interact within groups, the composition of these groups or "groupings" might influence their play behaviors. Understanding how said groupings may affect the play rates may help researchers better understand the development of behavior and social dynamics of the beluga groupings. The purpose of this study was to see whether grouping …

Does Shape Matter?: How Salamander Head Morphology Shifts Based On Environment, Caitlyn Pinaga, Naomi Ramirez, Sonia Cerrillo

Posters - 2026

Groundwater salamanders of the genus Eurycea represent a diverse group of amphibians inhabiting the aquifer systems of central Texas, where both surface-dwelling and fully subterranean species coexist. Subterranean habitats impose extreme selective pressures, including complete darkness, limited nutrient availability, and stable environmental conditions, which drive convergent morphological traits such as eye reduction or loss, decreased pigmentation, and elongation of appendages. A key evolutionary pattern seen in these systems is sensory compensation, in which the reduction of one sensory modality, in this case vision, is accompanied by the enhancement of others. In aquatic salamanders, this often involves expansion of the lateral …

Smell Over Sight: Determining Levels Of Olfactory Gene Expression Between Surface And Subterranean Eurycea Salamanders, Sonia Cerrillo, Iliana Melendez, Naomi Ramirez

Posters - 2026

In the karst aquifers of central Texas, including the Edwards and Trinity systems, organisms live in an environment defined by constant temperatures, total darkness, and scarce food resources. These conditions have driven the evolution of salamanders in the genus Eurycea, particularly those that have adapted to subterranean life. Cave-dwelling species like Eurycea rathbuni exhibit hallmark “blind salamander” traits, including educed eyes, loss of pigmentation, and flattened head morphology. In contrast, surface-dwelling relatives such as Eurycea nana and Eurycea sosorum retain fully developed eyes and pigmentation, while some species like Eurycea latitans display both surface and subterranean forms across different populations.

Gene Expression And Apoptotic Responses To Panobinostat Treatment And Yap Knockdown In Ewing Sarcoma Cells, Luna Collazo-Garcia, Alejandra Favela Santos, Madeline Torres-Salazar, Isabella Toscano

Posters - 2026

Ewing sarcoma is an aggressive pediatric cancer driven by abnormal gene expression caused by the EWS-FLI1 fusion protein

Usually treated with intensive treatments such as chemotherapy and radiation

Outcomes remain poor for metastatic disease, highlighting the need for new therapeutic strategies

The Hippo signaling pathway regulates cell proliferation and survival through the transcriptional co-activator YAP1

A Wealth Of Well-Being, Jake Grove

Furman Magazine

Jose Morales-Martinez '18 gives back to a community that has shown him so much.

2026 Spring Nutshell, Morehead State University. Institutional Research & Analysis.

Office of Institutional Research & Analysis Publication Archive

Spring 2026 issue of the Nutshell.

From Prediction To Prevention: How The Va Uses Analytics To Reduce Chronic Disease And Mental Health Risk, Leelakrishna Angadala

Undergraduate Student Symposium

Predictive analytics has become an essential component of preventive care strategies within the Veterans Health Administration (VHA), which serves a medically and psychosocially complex population at elevated risk for chronic disease and mental health conditions. This research examines how the VHA has leveraged predictive analytics to improve early identification, prevention, and targeted intervention for chronic illnesses and mental health disorders. Specifically, it explores established initiatives such as the Care Assessment Needs (CAN) score for identifying veterans at high risk of hospitalization or mortality, the Reach Out, Stay Strong, Essentials for Veterans (REACH VET) program for suicide risk prediction and prevention, …

The Role Of Hip Internal Rotation And Ground Reaction Forces On Lower Back Pain In Amateur Golfers, Katrina Arndt

Undergraduate Student Symposium

Lower back pain (LBP) is the most common musculoskeletal injury amongst golfers; the high velocity and repetitive motion of the golf swing on the lumbar spine leads to substantial compressive and torsional forces, making LBP primarily and overuse injury. An additional risk factor for LBP is limited lead hip internal rotation (LHIR), which forces the lumbar spine to compensate through excessive rotation. The golf swing also relies heavily on the efficient transfer of energy generated from the ground through the lower body, a process quantified by ground reaction forces (GRFs). While existing research has separately examined LBP and GRFs, there …