Digital Commons Network^™

Blood Flow Regulates Metabolism In Hematopoietic Development, Pamela L Wenzel

Faculty, Staff and Student Publications

Blood flow modifies oxygen availability and biomechanical forces within the vasculature of the embryo as the hematopoietic system develops. The aorta-gonad-mesonephros (AGM) envelops the largest artery in the body and is a critical site for the emergence of hematopoietic stem cells (HSCs). Herein, I discuss the role of hypoxia-inducible factors (HIFs) and force as determinants of metabolism and fate determination. To address the effects of blood flow on hematopoietic development, I employ mouse embryo models and biomimetic culture. Real-time cell metabolic analyses show that oxygen consumption rates (OCR) and extracellular acidification rates (ECAR) are altered by flow in cultures of …

Host Modulation Therapy In Periodontitis: From Established Therapies To Emerging Technologies, Aonjittra Phanrungsuwan, Jiaqi Huang, Neeraja Dharmaraj, Alejandra Cobos Perez, Omid Veiseh, Simon Young, Chun-Teh Lee

Faculty, Staff and Student Publications

Periodontitis is a biofilm-induced chronic inflammatory disease, characterized by gingival inflammation and alveolar bone loss. According to a national survey, approximately half of the U.S. adults are affected by periodontal disease. To effectively prevent and treat periodontitis, it is essential to address its underlying causes. The primary etiological factors include polymicrobial synergy and dysbiosis of the oral microbiota, and a dysregulated immune response. The standard therapeutic approach, mechanical removal of biofilm through debridement, sometimes demonstrates limited efficacy, particularly in cases of severe periodontitis, which may require adjunctive or additional therapy. Emerging evidence indicates that periodontal tissue destruction is initiated by …

Streamlining Eligibility Assessment For Alzheimer’S Disease-Modifying Therapies: Prediction Of Mmse Scores Using The Digital Clock And Recall, Ali Jannati, Claudio Toro-Serey, Marissa Ciesla, Emma Chen, John Showalter, David Bates, Alvaro Pascual-Leone, Sean Tobyne

Faculty, Staff and Students Publications

           Introduction: The eligibility of anti-amyloid disease-modifying therapies (DMTs) and their integration into clinical practice in some institutions requires a specific range of Mini-Mental State Examination (MMSE) scores. Reliance on this pencil-and-paper psychometric instrument imposes operational burdens and risks of perpetuating health disparities, given the test's known educational and cultural biases. This study evaluates the efficacy of the Digital Clock and Recall (DCR™)-a rapid, FDA-listed digital cognitive assessment-to crosswalk to MMSE scores using machine learning, thereby offering a faster, scalable, and equitable mechanism for patient triage.

Methods: We conducted a retrospective analysis using data from the multi-site Bio-Hermes-001 (BH) study ( …

Prophetic Preaching As A Tool For Social Justice, Trevor A. O'Reggio

Faculty Publications

No abstract provided.

“I Don’T Always See A Future For Me Here”: Oppressive Political Pressures On Lgbtq+ College Students’ Well-Being, Jodi Linley, Olivia M. Copeland, Kathleen J. Buell, Cindy Ann Kilgo, Megan Pendleton, Alex C. Lange, N F. Tennessen

Journal of Queer and Trans Studies in Education

In recent decades, colleges have broadly supported LGBTQ+ students. Now, institutions have shuttered LGBTQ+ initiatives in response to political pressures, with little consideration for the effects on students. This study answers the question, what current policy factors do LGBTQ+ college students describe as affecting their well-being, and in what ways? We analyzed 426 responses from a multi-institution study of LGBTQ+ students. By and large, students feel anxious and fearful as they navigate the current climate. Our analysis illustrated numerous factors, from the President and his administration to states and general emboldened violence, and the real and potential consequences of those …

Reconsidering The Definition Of Triple-Negative Breast Cancer In The Immune Checkpoint Inhibitor Era: An Optimal Cut-Off Value For Hormone Receptor Percentage Of Her2-Negative Invasive Breast Cancer, Takeo Fujii, Toshiaki Iwase, Yu Shen, Jami Fukui, Naoto T Ueno

Faculty, Staff and Student Publications

The optimal cut-off values of estrogen receptor (ER) and progesterone receptor (PgR) expression to define the positivity of ER and PgR have been under discussion for over a decade but remain controversial. The American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) and the St. Gallen International Expert Consensus recommended that breast cancers with ≥1% of ER or PgR expression should be considered hormone receptor (HR)-positive tumors but ER/PR expression of 1% to 10% should be reported as HR-low positive; however, among HER2-negative disease, data on the overall benefit of adjuvant endocrine therapies for patients with HR-low positive disease is …

A Preliminary Investigation Of Research Collaboration Through Scientific Paper Co-Authorship In The Gulf Of Mexico, Juliet Vallejo, Evelyn Roozee, Dongkyu Kim, Andrew M Song, Christopher A Gabler, Jasper De Vries, Antonia Sohns, Gordon M Hickey, Owen Temby

Faculty, Staff and Student Publications

It is well known that publications with collaborators from external institutions increase citations. This effect scales with spatial distance. There are also many barriers to long-distance collaborations, including linguistic differences, funding constraints, and the incremental costs of remote collaboration. This paper uses the Gulf of Mexico as a case study to examine long-distance research collaboration because it consists of three countries with diverse development levels and two prominent diplomatic languages, within a singular regional ecosystem of tremendous natural and economic value. This paper uses bibliometric network analysis to examine scientific research article co-authorship in the Gulf of Mexico from 2000 …

Digital Communication Strategies For Culinary Medicine In Cancer Prevention And Survivorship: Information-Seeking Habits And Content Preferences Of Online Cooking Media Among Adults Participating In Four Cancer Prevention And Control Cohort Studies, Margaret Raber, Sara Fares, Maria Vazquez, Larkin Strong, Carrie Daniel-Macdougall, Lorna Mcneill, Karen Basen-Engquist

Faculty, Staff and Student Publications

Introduction

Poor diet and excess weight have been linked to increased risk for at least 13 types of cancer. Culinary medicine utilizes experiential cooking skill development to improve individuals’ capacity for healthy eating. Digital communication strategies offer pathways for scalable culinary medicine interventions, but little research has explored how online cooking tools could be leveraged for cancer prevention messaging. We conducted a cross-sectional survey study exploring online cooking information-seeking habits and content preferences among participants in four cancer prevention and control cohorts to inform future digital culinary medicine interventions.

Methods

A cross-sectional survey study was conducted with a convenience sample …

Researching A New Religious Phenomenon Of The Central Asia: Digital Sufism, Bekzhan A. Azhimov, Nurlan Kairbekov, Jolaman Bulan, Tussipkhan Imammadi

Occasional Papers on Religion in Eastern Europe

This study examines the emergence of digital Sufism as a modern spiritual phenomenon. It investigates the participation of Sufi groups on social media, the themes conveyed in their online sermons, and the ways their digital strategies compare with other Islamic organizations. The article further explores how Sufi orders navigate virtual environments, questioning whether they reveal elements of esoteric knowledge in these spaces. The notion of digital Sufism is presented as a lens for understanding how Sufi traditions integrate modern technology to widen the influence and relevance of their teachings. The research highlights how Sufism has adjusted to the challenges of …

Legislative Support Of Religious Policy In Ukraine Under Martial Law, Volodymyr Karpunets, Andrii Shevchuk, Oleksandr Bilchuk

Occasional Papers on Religion in Eastern Europe

The article examines the legislative framework of Ukraine's religious policy under the conditions of martial law caused by the full-scale armed aggression of the Russian Federation. The constitutional foundations of state-confessional relations are analyzed, particularly the provisions of Article 35 of the Constitution of Ukraine on freedom of conscience and religion, as well as Article 64, which provides for the possibility of temporary restrictions on religious rights under martial law. Key legislative acts are reviewed: the Laws of Ukraine "On Freedom of Conscience and Religious Organizations" (1991, with amendments in 2018 and 2019), "On the Legal Regime of Martial Law" …

From The History Of The Arrival Of The True Cross In Georgia, Giorgi Sosiashvili, Aleksandre Mgebrishvili Prof. Dr.

Occasional Papers on Religion in Eastern Europe

This article explores the complex historical and theological narratives surrounding the arrival of the True Cross—the Life-Giving Wood—in Georgia, as preserved in medieval Georgian chronicles and ecclesiastical writings. Drawing upon primary sources such as the Conversion of Kartli, the chronicles of Leonti Mroveli, Nikoloz Gulaberidze, and Arsen Ikaltoeli, as well as later accounts by Prince Teimuraz, Niko Dadiani, and Platon Ioseliani, the study reconstructs the multi-layered tradition of how fragments of the Holy Cross were brought from Byzantium to Kartli during the reign of King Mirian. According to these sources, Emperor Constantine the Great and Queen Helena dispatched to Georgia …

Preservation Of Architectural-Religious Heritage In Modern Ukraine, Olga Gold, Maksym Vasalatiy, Olga Dobrodum

Occasional Papers on Religion in Eastern Europe

This article examines answers to a number of pressing questions regarding the preservation of architectural heritage in the modern world: what philosophical views underlie the preservation of world heritage; and what is unique about the protection of religious architectural heritage. The architectural philosophy of religious buildings represents a complex of original concepts, both material and spiritual. The hypothesis consists of constructing an algorithm and mechanism for protecting cultural heritage from the perspective of the philosophy of architecture in post-war Ukraine. The preservation of historical and cultural heritage sites is one of the most complex areas of activity in the fields …

Moral Quandaries In Extremis: The Last Thing By Leopold Lahola, Madeline Vadkerty

Occasional Papers on Religion in Eastern Europe

A review of Leopold Lahola, The Last Thing. Translated by Julia and Peter Sherwood. Prague, Karolinum Press, 2025. 217 pages, paperback, ISBN 978-80-246-6041.7

Frontmatter (Volume 46, Issue 4), Paul B. Mojzes

Occasional Papers on Religion in Eastern Europe

No abstract provided.

Eurasianism As The Ideological Foundation Of Putin's Russia: Protestant Dimensions., Pavlo Pavlenko

Occasional Papers on Religion in Eastern Europe

This article explores the ideological foundations of contemporary Putinist Russia, identifying Eurasianism as a primary socio-philosophical and geopolitical doctrine driving the Kremlin's imperial ambitions. The author traces the evolution of Eurasianism from its origins in "White émigré" circles to its current role as a conceptual bedrock for Russian fascism. A comparative analysis is provided between Eurasianism and the "Russian World" (Russkiy Mir) doctrine, highlighting their distinct approaches to ethnocentrism and continental unity. A significant portion of the study is dedicated to the "Eurasianization" of Protestant denominations within the Russian Federation, illustrating how these communities have been instrumentalized by the state …

Challenges Of The Religious Leadership In The Era Of Digitalization And Information-Communication Technology: The Example Of North Macedonia And Serbia, Vesna Zabijakin Chatleska, Marijana Maksimovic, Ruzhica Cacanoska

Occasional Papers on Religion in Eastern Europe

Abstract

The rapid development of the digitalization and the information-communication technology resulted in their wider use in the everyday professional and personal life, via various forms of its manifestation, such as, social networks, podcasts and artificial intelligence. The willingness and the capability of the religious leaders to accept information and communication innovations, and to adjust them to the existing specific structure of the religious communities, presupposes a strategic re-thinking of the religious practices and the relations with the believers in the online space. New technologies have enabled simpler and faster communication in religious communities, but with the use of digital …

Islamic Education And Imperial Governance: Kazakh Institutions In Turkestan (1867–Present), Mavluda Smanova

Occasional Papers on Religion in Eastern Europe

This article explores development of religious education among Kazakh populations within Turkestan Governor-Generalship from 1867 to the early twentieth century, placing it within wider context of imperial administration, Islamic intellectual heritage, and reformist initiatives. It contends that Islamic learning institutions were not merely shaped by colonial influence but operated as flexible and enduring systems deeply rooted in local social structures. Rather than suppressing these institutions, Russian imperial authorities adopted a policy of controlled integration, bringing them under administrative oversight while simultaneously promoting alternative educational models. This dynamic gave rise to diverse and negotiated educational landscape rather than a uniformly imposed …

The Phenomenon Of Professional Burnout Among Military Chaplains In Ukraine, Artem Makovskyi, Oleg Mateyuk, Oleksandr Bilovskyi, Anton Datskov, Dmytro Oleshko

Occasional Papers on Religion in Eastern Europe

The article presents a comprehensive study of the phenomenon of professional burnout among military chaplains in Ukraine in the context of their personal experience of being in extreme (combat) conditions. The relevance of the problem is due to the prolonged impact of combat operations, high psycho-emotional stress, and the special role of military chaplains in the system of moral and psychological support for Ukraine's security and defense sector. The theoretical and methodological basis of the study was the concept of professional burnout by K. Maslach, the provisions of the person-centered approach, and the theory of personal experience. The empirical study …

Two Fronts Of War: Physical And Spiritual: A Conversation With The Head Of The Chaplaincy Service Of The Land Forces Of The Armed Forces Of Ukraine– Larysa Polianska, Valentyna Kuryliak

Occasional Papers on Religion in Eastern Europe

She is an officer – and a woman. Emphasizing that she is not a military chaplain herself, she describes her role as a manager of the spiritual front. She is responsible for organizing the fulfillment of soldiers’ spiritual and religious needs and coordinating military chaplaincy activities. This conversation with Colonel Larysa Polyanska explores what it means for a woman to lead the chaplaincy service of the Land Forces of the Armed Forces of Ukraine, the reality of two fronts – physical and spiritual – and the pain of loss, prayer, and the power of words.

Frontmatter (Volume 46, Issue 5), Paul B. Mojzes

Occasional Papers on Religion in Eastern Europe

No abstract provided.

Socio-Psychological Portrait Of Muslim Women Who Joined Radical Religious Organizations, Akerke Sakbayeva, Nagima Baitenova, Zhuldyz Zhorabek, Assel Alimkhanova, Raimbek Zeinullin

Occasional Papers on Religion in Eastern Europe

This article examines the socio-psychological characteristics, motivations for radicalization, and the legal and social status of Muslim women who have joined radical religious organizations from gender and cultural studies perspectives. In recent years, the increasing involvement of women in violent extremist movements has intensified the need to investigate this phenomenon not only as a security issue, but also as a complex social, cultural, psychological, and gender-related phenomenon. The study analyzes both internal and external factors influencing the radicalization of women, including social marginalization, identity crises, emotional dependency, limited religious literacy, and perceptions of social injustice. Particular attention is given to …

Ideology And Law In Tension: The Macedonian Socialist Model Of Secularism And Its Constitutional Legacy, Aleksandar Spasenovski

Occasional Papers on Religion in Eastern Europe

This article examines the constitutional and ideological foundations of church–state relations in socialist Macedonia (1945–1990), situating them within the broader framework of socialist Yugoslavia. It argues that the Macedonian model of secularism was shaped by a structural tension between Marxist atheism as an official ideological doctrine and formal constitutional guarantees of freedom of religion. While constitutional texts affirmed separation and religious liberty, statutory regulation and political practice constrained the public role of religion and marginalized religious communities within the socialist legal order.

By analyzing ideological premises, constitutional provisions, and legislative instruments, the article identifies the defining paradox of the Yugoslav …

Ten Signatories, A Hundred Communities: Pluralization Without Consolidation In Slovenian Protestantism, Katja Brkič Golob

Occasional Papers on Religion in Eastern Europe

This article examines why contemporary Slovenian Protestantism exhibits a dual structure: a low‑variance Lutheran core (the Evangelical Church of the Augsburg Confession - ECAC) and a high‑variance neo‑Protestant field (mainly Pentecostal, Charismatic, Evangelical, and some Baptist communities). Using the public Register of Churches and Other Religious Communities as an administrative tracer of organizational volatility (first registrations, renamings, deletions), and situating findings in census/survey context, the study shows that post‑1991 legal liberalization enabled rapid formalization without automatic consolidation. A four‑lens framework—historico‑legal, sociological (church–sect–mysticism; religious‑economy), ecclesiological (order vs. movement), and psychological (charisma and its routinization; risks of authoritarian patterns)—explains why tensions in …

An Interdisciplinary Approach To Understanding The Social Ministry Of The Orthodox Church Of Ukraine In The Context Of Christian Theology And Socio-Humanitarian Sciences, Rostyslav Didukh

Occasional Papers on Religion in Eastern Europe

The article presents a comprehensive interdisciplinary scientific and theological analysis of the social ministry of the Orthodox Church of Ukraine (OCU) in the context of Christian theology and socio-humanitarian disciplines. Modern approaches of Orthodox theology to the social mission of Christianity ensure the integrity of the development of the human and society. The need to ensure the coherence of theological concepts of the Orthodox Church social teaching with the existing church and parish life, church educational mission, theological education, and social work is emphasized. Special attention is paid to the interdisciplinary connections of Orthodox theology, religious studies, psychology, pedagogy and …

The Canonical-Legal Status Of Autocephaly And Autonomy In The Context Of Pan-Orthodox Dialogue, Ivan Yovchev

Occasional Papers on Religion in Eastern Europe

Historical procedures for granting autonomy and autocephaly are not strictly standardized in canonical law and often rely on local traditions, agreements, and specific historical-political circumstances. This leads to a diversity of practices – from unilateral tomoses (decrees) of autocephaly issued by the mother church to decisions supported by a broader pan-Orthodox consensus. At the pan-Orthodox level, the question of how new autocephalous and autonomous churches are proclaimed has been under discussion since the Pan-Orthodox preparatory commissions of the 20th–21st centuries. Preparatory documents envisage the need for a pan-Orthodox agreement, with autocephaly to be granted through a tomos signed by the …

Islamic Identity In Post-Soviet Kazakhstan: Between Nation-Building And Global Religious Transformations, Ainur Adaikhan, Ainur Shormanova, Nurlan Orynbekov

Occasional Papers on Religion in Eastern Europe

This study examines the formation and expression of Islamic identity in Kazakhstan within the broader post-Soviet transformation of religion, nationhood, and state governance. Following decades of Soviet-imposed atheism, Islam re-emerged as a significant cultural and social force after independence in 1991. The objective of this research is to analyze how Islamic identity is constructed, expressed, and regulated in contemporary Kazakhstan, and to assess the interaction between ethnocultural belonging, institutional governance, and global religious influences. Methodologically, the study employs a mixed analytical approach combining theoretical interpretation, quantitative analysis of census and survey data, and institutional analysis of religious policy frameworks. Empirical …

Theological Foundations And Regional Adaptation Of Jihadist Ideology In Russia: Case Of The North Caucasus, Tilekkabyl Amangeldi, Gulzhan Rasheva

Occasional Papers on Religion in Eastern Europe

The growth of jihadist movements in the post-Soviet space has generated significant scholarly interest in the ideological and theological mechanisms that sustain militant mobilization. Russia, particularly the North Caucasus, represents an important regional context where global jihadist doctrines intersect with local political conflicts and historical narratives of resistance. This article examines the theological foundations of Russian jihadist movements in order to understand how militant actors reinterpret Islamic doctrines to legitimize violence and construct ideological authority. The study aims to analyze the key theological concepts that shape jihadist discourse in Russia and to explore how global Salafi-jihadist ideology has been adapted …

Religion At The Bedside: Institutionalizing Medical Chaplaincy In Ukraine’S Secular Healthcare Space And Its Moral Tensions, Iryna Horokholinska

Occasional Papers on Religion in Eastern Europe

The author conceptualizes medical chaplaincy in Ukraine as a phenomenon of significance for society and its value sphere. It is emerging at the intersection of the secular healthcare system, the social functionality of religion, wartime trauma, and the growing need for spiritual and existential care. The study demonstrates that, in the context of full-scale war, the social relevance of medical chaplaincy is not merely a pragmatic response to psychological and moral challenges, but also a systemic manifestation of the post-secular transformation of the public sphere characteristic of both Ukraine and the contemporary world.

The article further examines the legal and …

Security Challenges For The Activities Of Religious Organizations During Russian-Ukrainian War, Iryna Kondratieva, Iryna Fenno

Occasional Papers on Religion in Eastern Europe

In the article authors identify the greatest security challenges for religious organizations of Ukraine during Russian-Ukrainian war. In conditions of martial law, external threats and risks associated with the existential dimension become particularly acute. In the context of armed conflict and military operations, issues of survival assume paramount importance. Religious communities, like all other civilian populations, incur substantial losses and are perpetually vulnerable during the active phase of armed conflict. Security challenges are defined by authors as the most significant factor in changes in religious life in Ukraine during martial law.  Among them authors examine in detail war crimes in …

Frontmatter (Volume 46, Issue 6), Paul B. Mojzes

Occasional Papers on Religion in Eastern Europe

No abstract provided.