Digital Commons Network^™

Frequent Police Contact And Nonfatal Overdose Among People Who Use Drugs In Rural Appalachia, Javier A. Cepeda, Talia Loeb, Zach R. Salazar, Brittney D. Williams, Brooke Hiltz, Brandon Del Pozo, Eileen V. Pitpitan, Leo Beletsky, April M. Young, Jennifer R. Havens

Behavioral Science Faculty Publications

Introduction: Police contact shapes subsequent health practices and outcomes among people who use drugs (PWUD). However, the relationship between police encounters with overdose remains under-researched. We evaluated how police stop-and-search was associated with nonfatal overdose and identified correlates of frequent police contact among PWUD in rural Kentucky.

Methods: From May 2023– April 2024, 774 PWUD were enrolled in the Social Networks of Appalachian People and KyOSK studies. The exposure of interest was self-reported police stop-and-search in the past 6 months (0, 1–3, ≥4 times). The primary outcome was self-reported nonfatal overdose in the past 6 months. We evaluated the association …

Formative Research To Identify Contributors To Risky Drinking And Adapt An Alcohol Reduction Intervention Among Young Adults Vulnerable To Hiv: Qualitative Focus Group Study, Fidelis Y. Sesenu, Sally Kirklewski, Bryce Takenaka, Jaime Brown, Erin Nicholson, Kimberly Haney, Kaylia Carroll, Arjee Restar, Donte Travon Boyd, Keisa Fallin-Bennett, Trace Kershaw, Carolyn Lauckner

Communication Faculty Publications

Background: Across populations, risky drinking has been demonstrated to increase HIV risk behaviors. This is of special concern for sexually minoritized cisgender men and gender-diverse young adults (aged 18‐34 years), who report greater incidence of hazardous drinking (as defined by the Alcohol Use Disorders Identification Test - Consumption criteria) and HIV compared to their heterosexual and/or cisgender peers.

Objective: This study aimed to examine alcohol perceptions, patterns of use, and the role that anti-LGBTQ+ (lesbian, gay, bisexual, transgender, queer) policies and discrimination played in alcohol risk behaviors for sexually minoritized cisgender men and gender-diverse individuals. Results were used to inform …

Anatomical Atlas Of Kinase Responsiveness To Weight Gain: Adipose Depot Reprogramming In Diet-Induced Adiposity, Wang-Hsin Lee, Zachary A. Kipp, Sally N. Pauss, Genesee J. Martinez, Mei Xu, Terry D. Hinds, Jr.

Pharmacology and Nutritional Sciences Faculty Publications

Background/Objectives: Adipose tissue depots located at different anatomical sites exert differential functions in response to adiposity and glucose intolerance. These fat depots exhibit distinct metabolic signaling patterns that may influence pathological fat accumulation, thereby affecting the efficacy of anti-obesity interventions. Nonetheless, the mechanisms underpinning depot-specific signaling and pathway responsiveness remain insufficiently understood.

Methods: Kinase activity was characterized during the progression of adiposity across five adipose tissue depots in obese versus lean mice using the advanced PamGene kinome technology. Furthermore, kinase pathways in human preadipocytes and mouse 3T3-L1 preadipocytes were analyzed and compared with those in their differentiated, mature adipocytes. The …

Social Engagement Moderates The Relationship Between Cognitive Functioning, Depressive Symptoms, And Restless Sleep In Older Black Adults, Sunkanmi Folorunsho, Olufunmilola Abraham, Darlingtina K. Esiaka

Pharmacy Practice and Science Faculty Publications

INTRODUCTION: Older Black adults face higher dementia risk, but it is unclear whether social engagement offsets the effects of depression and restless sleep.

METHODS: We analyzed 1,905 Black adults aged 50+ from the 2016-2020 Health and Retirement Study (HRS). Linear mixed-effects models tested how depressive symptoms, restless sleep, and social engagement predicted baseline cognition and cognitive decline.

RESULTS: Higher depressive symptoms and restless sleep were associated with lower baseline cognition (about 0.2 and 0.5 points lower) and faster decline (β×time ≈ −0.07 and −0.05). Greater social engagement predicted higher baseline cognition (about 0.6 points higher) and slower decline (β×time ≈ …

Developing Curcumin Analogues For Treating Breast Cancer, Tulasi Laxmi Nutalapati

Theses, Dissertations and Capstones

Breast cancer is still one of the most common types of cancer and one of the most common causes of cancer-related deaths in women around the world. Despite significant advances in early detection and treatment strategies, drug resistance, systemic toxicity, and poor outcomes in aggressive subtypes continue to limit the overall effectiveness of cancer therapy. Natural compounds have become promising anticancer agents because they can target many different things and are not very toxic. Curcumin has shown promise as an anticancer drug, but it cannot be used in the clinic because it does not absorb well, breaks down quickly, and …

Investigation Of Reey Concentrations In Argillaceous Rocks Associated With Coal Beds In Southwestern West Virginia, Alyssa Cameron Long

Theses, Dissertations and Capstones

Rare earth elements (REEs) and Yttrium are classified as “critical minerals” that are used in many industries and are typically extracted from carbonatites and related alkaline plutonic rocks. The limited availability of REE+Y requires finding alternate sources such as coal fly ash, tonstein, fireclays, and shales. This study investigates the potential enrichment of shales, fireclays, and siltstones interbedded with coal from southwestern WV in REEY, and the mechanisms of such enrichment. Using ICP-AES analysis of various rock types shows that shales, silty shales, and siderite nodules interbedded with Fire Clay and Chilton Coal beds in the Kanawha Formation record the …

Validity And Reliability Of Force Insoles To Measure Center Of Pressure During Return-To-Sport Testing, Delaney Mcneese, Charles Eisner, Rachel Todd, Brian W. Noehren, Meredith K. Owen

Biomedical Engineering Faculty Publications

Center of pressure is a valuable biomechanical variable, predicting joint loading contributions during movement and giving insight into compensatory patterns. The purpose of this study was to assess the validity and reliability of force insoles in calculating vertical ground reaction force and center of pressure during return-to-sport jump testing. Ten healthy individuals performed double- and single-leg vertical and horizontal jumps on an instrumented treadmill while wearing instrumented force insoles. Vertical ground reaction force and anterior–posterior and medial–lateral center of pressure were collected at peak vertical ground reaction force from both devices. Repeat testing occurred 7 ± 5 days following the …

Non-Contact Optical Spectroscopy For Metabolic And Vascular Characterizations Of Orthotopic Tongue Cancer Models In Vivo, Md Zahid Hasan, Jing Yan, Sumit Sarker, Pranto Soumik Saha, Caigang Zhu

Biomedical Engineering Faculty Publications

Most tissue optical spectroscopy platforms use a fiber probe for light delivery and collection, while the inconsistent probe-sample contact could induce significant distortions in the measured optical signals, which consequently bring analysis errors. Moreover, it will be practically difficult to use a fiber probe for measurements in some cases such as oral cancer investigations using small animal models. To address the critical challenge, we report a portable, lens-based, optical spectroscopy device capable of quantifying key vascular and metabolic parameters in vivo without probe-sample contact. We combined lenses based diffuse reflectance and fluorescence spectroscopy into one portable platform to enable multi-parametric …

Combined Autofluorescence And Diffuse Reflectance Spectroscopy For Rapid Metabolic And Vascular Characterizations Of Orthotopic Tongue Tumors In Vivo, Pranto Soumik Saha, Jing Yan, Sumit Sarker, Zahid Hasan, Caigang Zhu

Biomedical Engineering Faculty Publications

Precise label-free quantification of tissue metabolic and vascular dynamics in vivo represents a critical challenge for cancer therapy prediction and longitudinal treatment assessment. In this study, we demonstrated a portable autofluorescence and diffuse reflectance spectroscopy device along with novel spectroscopic algorithms to quantify tissue vascular and metabolic parameters of orthotopic head and neck cancer models in vivo. Tissue-mimicking phantom studies were used to verify the dual-modal optical spectroscopy and easy-to-use spectroscopic algorithms for rapid and accurate estimation of tissue oxygen saturation, total hemoglobin contents, and intrinsic optical redox ratio. Animal studies were conducted to demonstrate the feasibility of our …

Noninvasive Diffuse Optical Monitoring Of Cerebral Blood Flow And Oxygenation Responses To Intermittent Hypoxia In Neonatal Rats, Pegah Safavi, Mehrana Mohtasebi, Chowdhury Azimul Haque, Faezeh Akbari, Xuhui Liu, Yiqi Yuan, Li Chen, Lei Chen, Guoqiang Yu

Biomedical Engineering Faculty Publications

Significance: Intermittent hypoxia (IH) is common in preterm neonates and can cause hypoxic–ischemic brain injury. Simultaneous monitoring of cerebral blood flow (CBF) and oxygenation is essential to detect oxygen delivery-extraction mismatches and guide intervention.

Aim: We aimed to adapt and test an innovative diffuse speckle contrast flow oximetry (DSCFO) system for continuous monitoring of cerebral hemodynamics during IH in neonatal rats, a model approximating human neonates.

Approach: Two compact laser diodes and a miniature CMOS camera were integrated into a fiber-free probe for continuous monitoring of changes in relative CBF (rCBF) and oxy- and deoxy-hemoglobin concentrations (Δ[HbO₂] and …

Successful Anesthetic Management Of Patient With Marfan Syndrome: Optimizing Cardiovascular Stability And Maternal Outcomes, M Roberts, C Cox, K Leavitt

South Atlantic Division GME Research Days 2026

No abstract provided.

Comparative Evaluation Of R134a And Hfo‐1234ze Cryogen Spray Cooling Using A Mouse Model With Controllable Epidermal Pigmentation, Wangcun Jia, Yurie Jeong, Crystal Huynh, Oswald Lai, Emily Nguyen, Grant Swajian, Jade Niu, Ayana Kashikar, Joshua Khaw, Hong Pu, Bernard Choi, John August D'Orazio, J. Stuart Nelson, Bahman Anvari

Pediatrics Faculty Publications

Objectives: Cryogen spray cooling (CSC) is critical for protecting the epidermis during laser dermatologic procedures. The widely used cryogen, R134a, has a high global warming potential (GWP), motivating interest in environmentally favorable alternatives such as HFO-1234ze. This study evaluated whether HFO-1234ze provides epidermal protection comparable to R134a during laser exposure and investigated the mechanistic basis underlying any differences in cooling performance.

Methods: Laser-induced epidermal injury in conjunction with two cryogens was assessed in K14-SCF Mc1r^e/e mice with pharmacologically controllable interfollicular epidermal pigmentation. Laser treatment sites were assigned fluences relative to baseline skin lightness (L*) to span subthreshold …

From Tension To Teaching: Combating Incivility And Bullying Behaviors Directed At Nursing Students, Shelley Dyal

Theses

Background: The phrase “nurses eat their young” has long been used to describe the culture of incivility and bullying often directed at nursing students. These behaviors in the nursing clinical learning environment break down nurse-student relationships. To address this issue, nursing staff must have the tools to fulfill their roles as educators and mentors in clinical settings. The purpose of this project is to implement and evaluate the effectiveness of an evidence-based asynchronous educational workshop focused on incivility reduction and student mentorship among nursing staff in a rural hospital setting.

Methods:  This study used a quantitative, one-group pretest–posttest intervention design …

Empowering Change: Impact Of Motivational Interviewing On First-Semester Nursing Students' Perceived Confidence And Communication Skills, Norma L. Branyon

Theses

Background: Effective communication is vital when interacting with others, regardless of the profession. When healthcare providers lack the skills to facilitate conversations about behavior changes, poor patient outcomes can be produced. New graduate nurses often encounter difficulties in effectively communicating with patients and display reluctance to engage with patients and their families. Ineffective communication may lead to increased anxiety, miscommunication, and mistrust. This communication gap can hinder therapeutic relationships, patient engagement, and overall health outcomes. Communication plays a crucial role in student nurses’ self-confidence, motivation, and personal and professional growth. Therefore, role transition for new nurses can be difficult and …

Genomic Characterization Of A Novel Bloom-Forming Cyanobacterial Species From Western Kansas., Louisa Acquah

Master's Theses or Doctor of Nursing Practice

Harmful cyanobacterial blooms are a danger to freshwater systems, particularly in water limited regions such as western Kansas, yet the genetic identity and diversity of bloom-forming taxa in this region remain poorly characterized. In this study, I investigated a cyanobacterial bloom in Horsethief Reservoir (Kansas, USA) in summer 2024 with the aim of resolving the taxonomic identity and genomic features of the dominant organism. Bloom water samples were collected, and the dominant cyanobacterium was enriched and rendered nearly axenic through controlled cultivation and repeated subculturing. Preliminary 16S rRNA gene sequencing indicated affiliation with the genus Limnothrix, but with notable …

The Effects Of Childhood Maltreatment On Executive Functioning: The Difference Between Cumulative Trauma, Abuse Severity, And Neglect, Kelly Krehbiel

Master's Theses or Doctor of Nursing Practice

Childhood maltreatment is prevalent in the United States with around 558,899 children being victims of abuse in 2022 (U.S Department of Health & Human Services, 2024). Neglect is the most common form of abuse with around 74 percent of abused children being neglected; however, neglect tends to be the least researched form of abuse. Childhood maltreatment has long-term effects on a person’s mental, physical, and cognitive health. Previous research suggests that childhood maltreatment leads to severe deficits in executive functioning skills such as working memory and cognitive flexibility. Executive functioning skills are important for almost every aspect of life including …

Exploring The Link Between Soil Microbes, And Land Use Through A One Health Lens, Yaw A. Antwi

Master's Theses or Doctor of Nursing Practice

The diversity of microbes within the soil plays an essential role in soil ecosystem

functioning. However, these microbes may also serve as environmental reservoirs for antibiotic resistance genes. The study examined the diversity of bacteria that are found in soil across Rural/Agricultural and Rural/Nonagricultural landscapes within some selected counties in Kansas and its associated antibiotic resistance genes taxa. A total of twenty-four soil samples was collected and analyzed using 16S rRNA gene amplicon sequencing which targeted the V3-V4 regions. Statistical analysis revealed that the alpha diversity metrics (Chao1 richness and Shannon evenness) showed no significant difference in microbial structure (p=0.693, …

Increasing Mental Health Literacy In An African Immigrant Community In The United States, Dominic T. Nchamukong

Master's Theses or Doctor of Nursing Practice

Abstract

Introduction: The aim of this quality-improvement project was to assess the impact of an educational intervention on mental health literacy, attitudes, stigma, and help-seeking behaviors among members of an African immigrant community in Maryland.

Framework: The Health Belief Model (HBM) guided implementation of the project. The intervention was delivered using HBM constructs to promote increased mental health literacy.

Methods: The study was conducted in four phases: pre-project preparation, recruitment, educational intervention, and post-intervention evaluation. The six-week program was delivered both online and in person. Participants completed pre- and post-surveys measuring knowledge, attitudes, stigma, and willingness to seek professional mental …

Protecting Your Largest Organ: A Journey In Skin Cancer Education, Prevention, And Early Detection, Krista Schneider

Master's Theses or Doctor of Nursing Practice

Rates of skin cancer diagnoses continue to increase globally, making skin cancer one of the most commonly diagnosed malignancies. Despite rising incidence, many individuals lack knowledge of risk factors, warning signs, and effective prevention strategies. This quality improvement project aimed to improve skin cancer awareness by providing targeted skin cancer education to young adults enrolled at a university in the Midwestern United States. Conducted from August 18 to December 1, 2025, this project followed the Plan-Do-Study-Act framework. Educational presentations were delivered to students enrolled in freshman seminar courses over a two-day period, accompanied by distribution of digital flyers and pamphlets. …

Fragments & Formations, Charles D. Schluckebier

Master's Theses or Doctor of Nursing Practice

My work begins with an idea, but is driven by curiosity as it develops, often arriving somewhere different than initially planned. I maintain control over the direction while allowing decisions to shift in response to what emerges. Creating artwork becomes a space where ideas are not illustrated by worked through – physically and mentally at the same time. I approach making as problem-solving, where each sculpture functions as a puzzle resolved through construction. I push materials beyond their intended function, forcing them into new conditions where form emerges through resistance, constraint, and play. Material behavior informs the outcome but does …

Mythology Of Whiteness: Constructing Black Girls As A Bully, Kathleen O'Brien, Pamela Twyman Hoff

Faculty Publications - College of Education

This analytical essay uses data from a qualitative study by O’Brien (2017) that explored the social construction of bullying. O’Brien interviewed 16 high school students enrolled in alternative and college-preparatory high schools. Although the study did not focus specifically on Black girls, their narratives surfaced a distinctly different story—one that exposed how whiteness, intersectional power, and cultural ways of knowing construct Black girls as quintessential bullies in schools. This re-analysis explores how Black girls are cast within the mythology of whiteness as archfoes—not merely as disruptive, but as symbolic antagonists whose existence threatens the normative order of whiteness …

The Impact Of School Climate On Student Achievement, Tonia L. Schiro

All Electronic Theses and Dissertations

This literature review explores the relationship between school climate and student achievement by examining research from education, psychology, and school improvement literature. School climate encompasses many aspects of the educational environment, including perceptions of safety, the quality of relationships among students and staff, levels of engagement, and students’ sense of belonging within the school community. The review investigates how these factors contribute to academic success and influence students’ overall educational experiences. Findings across the literature consistently demonstrate that positive school climates are associated with higher levels of student achievement, stronger engagement, improved attendance, and greater social-emotional well-being. The review also …

Collective Bargaining In The Usa : Union Success Within And Outside Of The Flawed Legal Framework, Angela B. Cornell

Cornell Law Faculty Publications

The labour movement in the US experienced a powerful upswing under President Biden, but even with a labour-friendly administration thousands of new bargaining units labour without collective bargaining agreements years a#er being organised. The many limitations and weaknesses of the collective-bargaining framework under the private-sector statute, the NLRA, contribute to this very unfortunate outcome including enterprise rather than sectoral bargaining, a lack of meaningful remedies for serious bargaining violations, very little interest arbitration when the parties cannot reach agreement and the extremely limited right to strike. Millions of American workers are deprived of the right to bargain collectively because of …

The Role Of Tumor Microenvironment In Glioblastoma Multiforme(Gbm) Therapeutic Resistance, Kwesi E. Taylor

Master's Theses or Doctor of Nursing Practice

Despite significant advances in cancer research and treatment, Glioblastoma multiforme (GBM) remains one of the most difficult cancers to treat effectively, with minimal improvement in long-term survival rates over the past few decades. This is largely attributed to tumor heterogeneity and the ability of tumor cells to develop adaptive resistance mechanisms supported by the tumor microenvironment (TME). Although the TME is recognized as a key contributor to tumor progression and therapeutic resistance, the underlying molecular pathways and regulatory genes remain incompletely understood. This study investigated the role of the tumor microenvironment in GBM therapeutic resistance using a bioinformatics approach. Single-cell …

Identifying Socio-Economic Areas Of Concern Towards Inclusion In Gis Hazard Management In Detroit, Michigan., Ernestina Osei

Master's Theses or Doctor of Nursing Practice

This study examined the spatial distribution of socio-economic vulnerability and accessibility to essential services in Detroit, Michigan, using a Geographic Information Systems (GIS)-based approach. The research aimed to identify areas of greatest concern by integrating socio-economic indicators, including poverty, housing vacancy, income, unemployment, and crime, with spatial measures of access to critical infrastructure such as hospitals, fire stations, police stations, and grocery stores. Both feature-based and raster-based analyses were employed, including buffer and overlay analysis, service area evaluation, Euclidean distance modeling, and multi-criteria suitability analysis.

A mixed-methods framework was adopted to combine quantitative spatial analysis with contextual understanding of urban …

Defend The Fort: Indigenous History, Remembrance, And Memorialization In Ellis County, Kansas, Sarah Keiss

Master's Theses or Doctor of Nursing Practice

This thesis provides an in-depth look into the Indigenous history of the area that would later become Western Kansas and Ellis County. Analyzing the history of the area from before European colonization to the Native American resistance against American expansion in the 1860s, this thesis illustrates the complex and layered history of the area. Even prior to European settler presence in the area, the native tribes felt the effects of European settlement and trade around them, leading to drastic changes in geographic distribution and access to new resources, particularly horses. Over the course of the nineteenth century, white settlement completely …

Bridging The Gap In Patient Attendance: A Dnp-Led Quality Improvement Project To Reduce No-Show Rate By Implementing Text Message Reminders, Charles D. Rogers

Master's Theses or Doctor of Nursing Practice

Missed medical appointments contribute to revenue loss, workflow inefficiencies, increased staff burden, and reduced patient access to care in primary care settings. This Doctor of Nursing Practice (DNP) quality improvement project evaluated the impact of an automated text message (SMS) reminder system on no-show rates in a privately owned, medium-sized family practice in a rural setting, aiming to reduce the baseline no-show rate of 11.4% to 10% or less. Guided by the Model for Improvement and the Plan-Do-Study-Act (PDSA) framework, automated SMS reminders were sent 48 hours prior to scheduled appointments. Existing 24-hour phone call reminders were maintained. Formative assessments …

Advanced Practice Workforce: ​Drivers Of Satisfaction & Retention​, Stephanie Bork, Amber Balzer, Sally Russell, R. K. Elswick Jr., Terry Jone, Kimberlee Ketchersid, Joseph Deranieri

School of Nursing Publications

Problem

The turnover of advanced practice registered nurses (APRNs) is costly for institutions and creates gaps in care for organizations. The aims of this study are to describe the characteristics of the APRN and PA workforce in a large, integrated academic medical center and examine relationships between APRN and PA workforce characteristics and organizational outcomes.

Background

APRNs encompass a diverse group of licensed clinicians and are integral to healthcare delivery. As APRNs roles expand to support healthcare needs, turnover is costly and adversely affects patient care. The APRN role remains constrained in many healthcare institutions, contributing to burnout and job …

The Impact Of Somali Parental Involvement On Elementary Education In Minnesota: Opportunities And Challenges, Abdiqani Abdullahi Elmi

All Electronic Theses and Dissertations

Abstract This qualitative study examines the challenges faced by Somali-American parents in Minnesota regarding involvement in their children's education, particularly during elementary school. The elementary level is a critical stage for students' learning and a foundational pillar for both academic development and social integration, making parental involvement during this stage especially important. However, immigrant families, specifically Somali-Americans, face significant challenges that impede their ability to participate actively in their children's educational journey. This qualitative phenomenological research investigated barriers that might stem from limited formal education, low English proficiency, cultural, linguistic, and socioeconomic challenges. The methodology used in this research is …

The Role Of Mentorship In Women’S Pathways To Senior Superintendency Positions In K–12 Public Education, Tara Falasco

All Electronic Theses and Dissertations

Although women comprise the majority of the K–12 workforce, they remain underrepresented in senior superintendency leadership positions, a disparity attributed to systemic and social factors such as implicit bias, gender stereotypes, limited access to professional networks, and inequitable mentorship and sponsorship structures that restrict advancement opportunities. Mentorship is widely recognized as an important factor in women’s pathways to senior roles; however, women often report less access to advocacy-oriented sponsorship than men, leaving those in building-level leadership (e.g., principals, assistant principals) facing barriers—such as limited access to networks, implicit gender bias, and work–life balance challenges—when seeking senior superintendency positions. This phenomenological, …