Digital Commons Network^™

Perception Of Dementia Risk Among Black Adults: An Ecological Analysis Of Causal Loop Diagrams With A Structural And Social Determinant Of Health Composite Index, Jean-Francois Trani, Ramkrishna K Singh, Alexis Ib Walker, Semere Bekena, Yiqi Zhu, Ganesh M Babulal, Robbie Hart

2020-Current year OA Pubs

INTRODUCTION: To investigate drivers of dementia risk disparities among older Black Americans using a community-based system dynamics (CBSD) approach.

METHODS: Over 18 months, 234 participants created 36 causal loop diagrams (CLDs) on dementia risk. An ecological analysis compared structural differences across groups based on scores on a structural and social determinants of health composite index (S/SDOH-CI).

RESULTS: Groups in the highest SDOH-CI quantile were more likely to identify key protective pathways linking mental health, substance use, exercise, medication, and community support to reduce dementia risk. In contrast, fewer than 25% of low-SDOH-CI groups identified these connections, and under 15% recognized …

The Association Between Major Depressive Disorder, Plasma Biomarkers Of Alzheimer's Disease, And Mild Behavioral Impairment Among Older Adults, Yiqi Zhu, Jean-Francois Trani, Ramkrishna K Singh, Semere Bekena, Jonathan Williams, Eric J Lenze, Ganesh M Babulal

2020-Current year OA Pubs

INTRODUCTION: Plasma biomarkers and mild behavioral impairment (MBI) are associated with dementia risk, but their relationships with major depressive disorder (MDD) are understudied. This study aimed to examine associations between plasma biomarkers of Alzheimer's disease (AD) and MBI among older adults with and without MDD.

METHODS: Older adults aged ≥65 were recruited from longitudinal studies of depression and AD (

RESULTS: Older adults with MDD were more likely to endorse MBI. After adjustment, Aβ42/Aβ40 and p-tau217/np-tau217 positivity were associated with MBI among those with MDD but not among those without.

DISCUSSION: Neuropsychatric symptoms (NPS) and biomarkers are AD risk factors. …

The Impact Of Congenital Heart Disease On The Timing Of Alzheimer's Disease In Down Syndrome, Julianne G Clina, Beau Ances, Et Al.

2020-Current year OA Pubs

INTRODUCTION: The incidence of Alzheimer's disease (AD) in Down syndrome (DS) exceeds 90%. Approximately 50% of people with DS have congenital heart disease (CHD). Having CHD increases risk for early-onset AD in populations without DS, but it is unclear if CHD influences AD in DS.

METHODS: Data from the Alzheimer Biomarker Consortium-Down Syndrome (ABC-DS) were used. Participants with CHD (

RESULTS: People with CHD scored lower for visuospatial ability (

DISCUSSION: Presence of CHD may influence AD progression in DS.

HIGHLIGHTS: In adults with Down syndrome (DS), those with congenital heart disease (CHD) had higher amyloid beta and reached the …

Relationship Among Sleep Disturbance, Stress, And Suicidal Ideation In Clinical High Risk For Psychosis, Heather M Wastler, Daniel Mamah, Et Al.

2020-Current year OA Pubs

BACKGROUND AND HYPOTHESIS: Sleep disturbance is a well-established risk factor for suicide, though few studies to date have examined whether sleep disturbance contributes to suicide risk among individuals at clinical high risk for psychosis (CHR). The current study addressed this gap in the literature. We hypothesized that sleep disturbance would have a unique relationship with suicidal ideation/attempts when accounting for other variables in the model. We also hypothesized that the interaction between sleep disturbance/attenuated positive symptoms and sleep disturbance/stress would be related to suicidal ideation/attempts in CHR.

STUDY DESIGN: The current study used data generated by the Accelerating Medicines Partnership® …

Errors And Misconceptions In Mathematics Teacher Retraining: An Investigation Of Subject Knowledge Enhancement Course Results, Gabor Szalontai

School of Law, Humanities and Social Sciences Theses

This thesis investigates the subject knowledge capabilities and deficiencies of teachers who wished to enter or return to secondary mathematics teaching and took part in the Subject Knowledge Enhancement Plus programme. It focuses on the proportions, types and causes of their mistakes, as well as their potential for development and the possibility of increasing their awareness of errors.The study uses recorded responses of 1602 participants from the online assessment of the courses, which ran across England. The assessment, covering the entire secondary curriculum and consisting of 643 questions, provided an interactive, multiple-attempt design allowing the investigation of the participants’ results …

Improving Primary Initial Teacher Training (Itt) Trainees’ Confidence In Mathematics Teaching, Pinar Gumus

School of Law, Humanities and Social Sciences Theses

This research aimed to investigate how primary ITT trainees’ confidence in teaching mathematics could be improved through the curriculum coherence approach. A convergent mixed-method case study design was employed, collecting both quantitative and qualitative data from undergraduate trainees over three years via questionnaires. University mathematics tutors and selected school-based mentors were also interviewed using a semi-structured format.Following the analysis of the first year’s questionnaires, a new mathematics curriculum was designed for the second year of the study. As required by DfE and Ofsted, teaching plans and resources incorporated conceptual mathematics techniques, theory-practice links, and the Core Content Framework (CCF). The …

“We're Just Glorified Babysitters.” : Early Years Educators' Perspective On Learning And Expertism, Hayley Fisher

School of Law, Humanities and Social Sciences Theses

This qualitative study explores early years educators’ perceptions of learning and expertise, emphasising how they experience, develop, and articulate their professional knowledge in early childhood education. Based on ten in-depth semi-structured interviews, it critically examines the often complex and conflicting ways educators view their roles, identities, and professional development. The research is rooted in adult learning theories, including Knowles’ (1972) andragogy, Kolb’s (1984) experiential learning model, and Mezirow’s (1997) transformative learning theory, alongside Eraut’s (1994) work on professional knowledge and expertise, which highlights the relational, practice-based, and social dimensions of knowledge formation. Through thematic analysis, four key themes emerged: expertee-ism, …

"Tell Me About Your Esol Experience": Exploring Language Journeys Through Shared Stories, Rocio Rivero-Gutierrez

School of Law, Humanities and Social Sciences Theses

This thesis explores the English language learning experiences of ESOL(English for Speakers of Other Languages) participants from southern Spain, examining the interplay between language acquisition, cultural adaptation, andidentity transformation. Grounded in my own ESOL journey — shaped both inSpain and through immersion in an English-speaking context — the studyinvestigates how participants assign meaning to their L2 engagement acrossdiverse social settings, and how English becomes a tool for bothcommunication and personal reinvention. The research adopts a qualitative, narrative-based methodology. The datawere generated through in-depth interviews, small group discussions, andreflective journal entries with nine adult participants, all native Spanishspeakers. Crucially, the data …

Exploring And Increasing Women’S And Girls’ Recreational Ocean Access In A Coastal Community In The Tropical Majority, Florence Barraud

School of Law, Humanities and Social Sciences Theses

Vast gender inequalities restrict women’s and girls’ access to ocean spaces, particularly in the tropical majority. Globally, 68% of women cannot swim, compared to 43% of men. In many coastal communities, women are key stewards of highly biodiverse yet vulnerable marine environments that people rely upon for food security, livelihoods, culture, and coastal protection. Being able to swim is imperative for enabling access to the dominant environment and a core recreational, educational, and economic space. This study aimed to explore and increase women’s and girls’ recreational ocean access in the Maldives, a tropical majority island nation.Utilising a pragmatic feminist approach, …

Safe Family Therapy Activities And The Emotional Well-Being Of Parents Of Autistic Children, Gamze Camci

School of Law, Humanities and Social Sciences Theses

This thesis addresses a critical gap in the existing literature on the emotional well-being of parents of autistic children by applying SAFE family therapy activities grounded in the Narrative Attachment Therapy approach through a three-cycle action research design. Stage 1 involved 3 parents as primary participants, with their children present during selected sessions. Stage 2 included 2 families; the primary focus was on 3 parents across these families. Stage 3 engaged 5 therapists. Data were collected through interviews, diaries, questionnaires and therapy recordings. Data from interviews and journals were analysed thematically, whereas questionnaires were analysed idiographically. The first and second …

Exploring The Reading Motivation And Reading Experiences Of Secondary School Students With Dyslexia In England, Ahmet Kaan Alper

School of Law, Humanities and Social Sciences Theses

This research examines how a small group of secondary school students with dyslexia in England make sense of their reading experiences and motivation to read across school, home and everyday settings. It responds to concerns that literacy policy and practice foreground accuracy, speed and comparison, leaving limited space for reading for pleasure on students’ own terms. Drawing on Michel Foucault’s concepts, the study treats dyslexia and literacy as historically and institutionally produced categories and explores how discourses, norms and accountability regimes shape what counts as legitimate reading and a motivated reader. The research is grounded in a relativist ontology and …

Social And Emotional Experiences Of Higher Education Students With Dyslexia In Türki̇Ye And England: Exploring The Effect Of Context, Levent Yigit

School of Law, Humanities and Social Sciences Theses

This research study examined the social and emotional experiences of university students with dyslexia in Türkiye and England who had received an official diagnosis at some point in their lives. Findings were compared and the differing experiences in two different countries highlighted. Six students in Türkiye and five students in England participated in the study. To produce an in-depth subjective dataset capturing life-stories, a qualitative narrative approach was adopted. Three, and for some participants four, consecutive semi-structured interviews were conducted, with at least a one-week interval between each interview. The study adopted a longitudinal approach as each interview investigated students’ …

The Effects Of Altered Partial Pressures Of Gas On Cognitive And Neural Function, Daniel Graham

School of Psychology Theses

Oxygen is central to neural function, yet the precise mechanisms and effects by which varying oxygen levels, whether through Hypoxia, Hyperoxia, or Hyperbaric Oxygen Therapy (HBOT), shape cognition and brain activity remain incomplete. This thesis adopts a novel, multi-modal framework that integrates normobaric gas manipulations, cognitive testing, Transcranial Magnetic Stimulation (TMS), Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), and HBOT to examine how gas and pressure variability influences cognitive, motor, and neural processes. Chapter 3 presents the findings of a preliminary experiment investigating normobaric oxygen manipulations on cognition. Standardised cognitive assessments revealed domain-general impairments (i.e. memory and executive function) under …

Trialing A Novel Method Of Skin Mucus Sampling To Measure Stress And Reproductive Steroid Hormones In Mobula Species Mobula Alfredi And Mobula Munkiana, Bethany Faulkner

School of Biological and Marine Sciences Theses

Anthropogenic pressures, exacerbated by exceptionally slow population growth, have led to all mobulid species being listed on the IUCN Red List. Understanding stress and reproductive physiology is essential for improving mobulid conservation strategies. However, few studies have investigated the hormonal processes that underlie stress responses and reproductive physiology in mobulids. Studies on fish species have identified positive correlations between steroid hormone concentrations in blood and skin mucus, the collection of the latter being a much less invasive technique. This pilot study examined the feasibility of using skin mucus as a non-invasive matrix for detecting steroid hormones in two mobulid species. …

A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes

Peninsula Dental School

Introduction The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health interventions consider gender as part of their approach. The aim of this pilot study was to test the hypothesis that the oral microbiome and microenvironment change during female ageing and are thus worthy of further consideration both experimentally and clinically. Methods This observational pilot study retrospectively assessed women aged 18 to 89 years (n = 60) attending a UK primary care dental school facility for blood pressure …

Seeing Anxiety: Ecological Video Ethnography And Simulation To Understand Anxiety And Decision-Making In Dental Care, Mona Nasser, Hannah Drayson, Sally Hanks, Nicholas Peres, Michael Punt

Peninsula Dental School

BACKGROUND: Dental anxiety is a widespread barrier to care, often contributing to appointment avoidance, treatment disruption, and emotional strain for both patients and clinicians. While extensively studied as a psychological trait, less attention has been paid to how anxiety manifests situationally and relationally, through non-verbal, affective, and spatial cues within clinical encounters. Moreover, in certain contexts, such affective signals can intersect with decision-making processes, shaping how patients interpret, engage with, or withdraw from clinical choices.

OBJECTIVE: To explore how anxiety manifests within the micro-choreography of dental encounters, develop a taxonomy of 'anxious tells', and assess the utility of ecological video …