Digital Commons Network^™

Diffusion-Informed Joint Segmentation Enhances Detection Of Thalamic Atrophy In Parkinson’S Disease, Gozde Kizilates-Evin, Ani Kicik, Emel Erdogdu, Dilek Betul Saridede, Sevim Cengiz, Basar Bilgic, Hasmet A. Hanagasi, Esin Ozturk-Isik, Tamer Demiralp, Ali Bayram

All Works

The thalamus is a critical subcortical hub that relays sensorimotor information and regulates higher-order cognitive processes. Accurate delineation of thalamic nuclei is essential for elucidating disease mechanisms and tracking clinical progression. In this study, we compared two segmentation approaches implemented in FreeSurfer: the conventional structural method and a joint framework that integrates diffusion tensor imaging. Magnetic resonance imaging (MRI) data from 24 healthy controls (HC), 27 patients with cognitively normal Parkinson’s disease (PD-CN), and 33 Parkinson's disease patients with mild cognitive impairment (PD-MCI) were analyzed. Segmentation methods were compared in HC to assess their effect on volume estimates. Group comparisons …

Assessment Of Glycemic Control Among Patients With Type 2 Diabetes Mellitus Attending A Tertiary Diabetes And Endocrinology Center In Sulaymania City/ Iraq, Lina Ali Al-Khafaji, Bahjat Abdulridha Alsaeedy

Muthanna Medical Journal

Introduction: The sociodemographic and clinical factors play a role in type 2 Diabetes Mellitus (T2DM) glycemic control.
Objectives: To assess glycemic control among T2DM patients and its association with sociodemographic and clinical factors.
Materials and methods: A prospective observational study of 210 patients with T2DM at a tertiary diabetes and endocrinology center in Sulaymania city/ Iraq, from April to November 2024. The study involved sociodemographic data, body mass index, blood pressure, and blood tests for HbA1c, fasting blood sugar, total cholesterol, LDL, HDL, triglycerides, blood urea and creatinine. The performed HbA1c tests were compared with baseline results to identify differences, …

Best Practices For Supporting Occupational Therapy Students With Disabilities During Clinical Education: Results From A Three-Round Delphi Study, Courtney Gohean, Katie Mclaughlin, Aster Harrison

Department of Occupational Therapy Faculty Papers

INTRODUCTION: Disabled occupational therapy students face systemic barriers in clinical education. Although legal mandates require reasonable accommodations, implementation is often inconsistent, and few standardized guidelines exist for fieldwork education. This study is aimed at establishing best practices for supporting occupational therapy and occupational therapy assistant students with disabilities during fieldwork.

MATERIALS AND METHODS: A three-round Delphi study was conducted with a panel of 30 experts, including disabled occupational therapy students, disabled occupational therapy practitioners, academic fieldwork coordinators (AFWCs), fieldwork educators (FWEs), disability services staff, and researchers. In Round 1, participants answered open-ended questions about challenges, accommodations, and environmental supports. Responses …

The Impact Of Gun Control Policies On Firearm-Related Deaths: A Two Decade State-By-Year Analysis, Rabana Tajrin

Dissertations, Theses, and Capstone Projects

This report analyzed firearm-related deaths rates in the United States at the state level over a two decade period between 2000 to 2019. The study used a state-by-year analytical framework created from the U.S. Gun Deaths by County, 1999–2019 dataset (Eltom, 2019) in order to examine national trends, state-level differences, changes over time, geographic concentration, and regional variation. The analysis focused on firearm-related deaths by adjusting for population size differences (i.e., the crude firearm-related death rate) across U.S. states from 2000 to 2019. These analyses indicated that firearm-related deaths increased nationally during the study period. Total firearm-related deaths rose from …

Allyship And Affect: Qualitative Investigations Into Social Transformation, Michael Lucinda Jane Greer

Dissertations, Theses, and Capstone Projects

Allies have faced several critiques in feminist philosophy. Some have argued that they lack the requisite political interests to be motivated to dismantle the social structures from which they stand to benefit. Others have argued that the epistemic limitations resulting from their social privilege are insurmountable. Yet others have argued that allyship is too individualistic a concept, preferring a more collectivist concept like solidarity. However, there remain privileged individuals who understand themselves as complicit in perpetuating oppressive forms of life, and who wish to transform themselves and work in coalition across difference to dismantle structural oppression. How ought these individuals …

Authoritarianism, Hostility And Threat: An Analysis Of American Political Podcasts Surrounding The 2024 Presidential Election, Noah D. Cohen

Dissertations, Theses, and Capstone Projects

Political rhetoric surrounding key events has seen sharp increases in emotionally affective speech, intergroup sentiment, and rhetoric unbecoming of democratic societies in recent years. Similarly, semi-democratic and ideologically driven speech has become increasingly normalized within an era of political polarization and hardline beliefs in modern media. Within this economy of outrage, sensational and largely unmoderated media formats, particularly podcasts, have become a mainstay of political information and discourse. This raises an important question: how does rhetoric surrounding political events construct intergroup sentiment and authoritarian rhetoric within political media, particularly American political podcasts? Further, given political podcasts’ growing social influence in …

Intimate Partner Violence And Emotion Regulation Among Emerging Adults: Investigating The Roles Of Dispositional Mindfulness And Executive Function In The Context Of A Laboratory-Induced Stress Paradigm, Mikell Bursky

Dissertations, Theses, and Capstone Projects

Intimate Partner Violence (IPV) is a major public health concern that impacts an estimated 10 million men and women in the United States annually. IPV refers to a range of physical, sexual or psychological forms of aggression committed against a current or former romantic partner in the context of a relationship. The highest rates of IPV are observed in emerging adulthood, a developmental period between the ages of 18 to 25 that is significant for the transition from adolescence into adulthood, and the establishment of first meaningful intimate relationships. Although distal risk factors for IPV such as violence in the …

The Cranial Nerves And Electrical Stimulation, Devin K. P. Adair

Dissertations, Theses, and Capstone Projects

Cranial nerves provide afferent pathways that enable bottom-up modulation of central autonomic and cognitive neural pathways. Because these pathways project to brainstem nuclei such as the nucleus tractus solitarius and engage neuromodulatory systems, including the locus coeruleus, electrical stimulation offers a mechanistically grounded approach to influencing brain function. This thesis tested whether active transcutaneous auricular vagus nerve stimulation (taVNS) produces physiological responses indicative of parasympathetic engagement, defined as decreases in heart rate, increases in heart rate variability, and decreases in respiration relative to a dose-matched earlobe control condition. Using cardiac and respiratory measures as physiological markers, taVNS at the tragus …

Teaching Third Graders To Read Multisyllable Words: Segmentation Versus Whole Word Reading, Jolie D. Heath

Dissertations, Theses, and Capstone Projects

In the early years of elementary school when children are still learning to read, they are presented with words of increased syllable length, and orthographic and morphological complexity in the texts they read.  Although multisyllabic words comprise 90% of words in the English lexicon and carry important linguistic information for expanding vocabularies and comprehension of content, few studies have focused on teaching middle elementary children to read multisyllabic words.  Many children lack strategies to identify these longer more complex words accurately and easily, leading to reading difficulties that place weaker readers at higher risk for school related problems and limit …

The Effects Of Chronic Nicotine Exposure On Dopamine-Mediated Reinforcement Learning And Striatal Neurotransmission, Srishti Bose

Dissertations, Theses, and Capstone Projects

Tobacco is one of the most widely used substances across the United States; tobacco consumption is linked with several diseases and is one of the leading causes of preventable death in the country. Nicotine is the active substrate found in tobacco products, acting as a stimulant, which reinforces continued use. The introduction of tobacco-free options such as e-cigarettes and oral pouches has driven an increase in nicotine exposure across the population, especially in young adults. Acute nicotine use induces neuroadaptations in the mesolimbic dopaminergic system, which mediates reinforcement learning and addiction, that potentiates reward-related neurotransmission. Furthermore, there are clinical studies …

Retrieval Information From Working Memory: The Output Gating Framework Perspective And Its Underlying Processes, Chen Tiferet-Dweck

Dissertations, Theses, and Capstone Projects

Working memory (WM) keeps information accessible and available for further processing. However, not all the information we maintain in WM is behaviorally relevant at any given moment. To act effectively, we must dynamically control which memory representations are accessed to support ongoing goal-directed behavior. While the mechanisms underlying the selection of single items from WM access are comparatively well-studied, less is known about the principles governing multi-item access. Existing models of WM access imply that selecting multiple items should take longer and be more error-prone than single-item access. Yet, paradoxically, prior studies have shown that retrieving all items in WM …

The Role Of Temperament In Criminal Trajectories: Development, Stability, And Predictive Power Across The Life Course, Joshua A. Lang

Dissertations, Theses, and Capstone Projects

Temperament, an individual's largely innate tendency to experience and regulate responses to their environment, has long been studied but was only recently introduced as a primary predictor of criminal behavior (DeLisi & Vaughn, 2014). While prior criminological theories have incorporated temperament-related constructs, such as negative affect (Agnew, 1992; Moffitt, 1993) and self-control (Gottfredson & Hirschi, 1990), no other theory has explicitly positioned temperament as the central factor in offending. DeLisi and Vaughn’s temperament-based theory of antisocial behavior posits that individuals with low effortful control and high negative emotionality—features of a difficult temperament—are more likely to engage in criminal behavior. Despite …

Towards Identifying Fear And Safety Network States Across Sex, Rhonda Kolaric

Dissertations, Theses, and Capstone Projects

Post-traumatic stress disorder (PTSD) is a trauma- and stressor-related disorder with a lifetime prevalence of 5-6% in men, and 10-12% in women (National Center for PTSD). Generalized anxiety disorder (GAD) is a highly prevalent anxiety- and depression-related psychiatric disorder with a lifetime prevalence of 1-2% in men, and 3-4% in women (National Institutes of Health). Both of these disorders disproportionately affect women. A hallmark feature of both disorders is the maladaptive generalization of fear, in which defensive responses extend beyond the original traumatic or threatening stimulus to neutral or unrelated cues. This overgeneralization can become debilitating, disrupting cognitive, emotional, and …

New York City Women’S Experiences With Perinatal Depression Inquiries, Diagnosis, And Treatment Initiation, Caterina Pisciotta

Dissertations, Theses, and Capstone Projects

Perinatal depression represents a significant public health concern, yet many women who experience depression symptoms during the perinatal period (either during pregnancy and/or after birth) do not receive treatment. Initiatives, such as ThriveNYC, were designed to address these gaps by screening and treating perinatal women for maternal depression, integrating screening into routine perinatal care and strengthening pathways to treatment. Using representative survey data collected between 2016 and 2021 via the Center for Disease Control and Prevention’s Pregnancy Risk Assessment Monitoring System (PRAMS), this study examined trends in perinatal depression inquiries (a proxy for “screening”) and postpartum diagnosis, as well as …

Tennessee Archivist 45, No. 4, Society Of Tennessee Archivists

Tennessee Archivist newsletters

Fall 2026 issue of the Tennessee Archivist, a newsletter produced by the Society of Tennessee Archivists.

Parenthood And Re-Appraisal Of Childhood Maltreatment, Gayathri Cheran

Dissertations, Theses, and Capstone Projects

Background: Child maltreatment is associated with poorer physical and mental health outcomes across the lifespan.  Individuals’ appraisals of childhood maltreatment have important implications for these outcomes.  Appraisal is shaped by biological, psychological, and social-cultural factors, each of which undergoes change in parenthood.  Parenthood may prompt re-appraisal of childhood maltreatment in that being a parent evokes one’s experience of being parented.

Hypotheses: (1) Re-appraisal will be more likely in parents than non-parents.  In parents, re-appraisal will be more likely among: (2) primiparous parents, (3) parents with offspring of the same sex, and (4) parents who experienced maltreatment older in childhood (at …

Scrolling Through Stress: Physiological Stress Recovery Shapes Risk For Problematic Social Media Use In Young Adults With Depressive Symptoms, Abigail Findley

Dissertations, Theses, and Capstone Projects

Depression is among the most consistent correlates of problematic social media use (PSMU), yet how depressive symptoms confer this risk, and for whom, remains poorly understood. The present study examined whether stress regulation explains the link between depressive symptoms and PSMU in young adults, testing specifically whether stress recovery acts as a mechanism linking the two or as a vulnerability that determines for whom they are linked, and whether distress tolerance (DT) shapes these pathways. Participants (N = 77) were young adults (18–25) with elevated depressive symptoms. Following the Trier Social Stress Test, participants completed a 15-minute social media …

The Development And Piloting Of A Novel Client-Rated Trans And Gender Expansive Clinical Competence Scale For Mental Health Providers, Karen Abraham

Dissertations, Theses, and Capstone Projects

Transgender and gender expansive individuals (TGEI) are people who encompass a broad and comprehensive set of experiences of gender diverse individuals and identities that exist both within and beyond a binary framework. In the United States, the Williams Institute identified a proportion of 0.5% of American adults identifying as transgender (Herman et al., 2022). TGE samples report poorer physical and mental health than their cisgender counterparts across the lifespan (Rastogi et al., 2025; Reisner et al., 2015; Reisner, Poteat, et al., 2016). Health disparities of TGEI relative to their non-TGE counterparts can be seen in the prevalence of mood disorders …

Using Early And Periodic Screening, Diagnostic, And Treatment (Epsdt) To Improve Access To Obesity Pharmacotherapy: A Practical Guide For Clinicians Caring For Youth With Obesity Across United States Medicaid Programs:, Jaime M. Moore, Valerie M. O'Hara, Cassie Totman, Brooke Sweeney, Sarah Hampl, Alaina P. Vidmar

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Coverage of obesity pharmacotherapy for youth varies substantially across state Medicaid programs. This variability limits access to evidence-based treatment for pediatric obesity. The Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) benefit is a federally mandated Medicaid provision requiring coverage of medically necessary services for individuals under age 21, even when such services are not included in standard state Medicaid benefits. Despite its broad scope, EPSDT remains underutilized due to limited awareness and operational complexity.

METHODS: We developed a clinician-facing, practice-oriented framework to operationalize EPSDT for pediatric obesity treatment. This approach integrates (1) review of federal EPSDT policy and …

Non-Vigorous Physical Activity Associated With Reduced Hospitalization Risk With Or Without Diabetes Or Peripheral Artery Disease: Study Of Latinos., Sarah K. Alver, Carmen C. Cuthbertson, Kelly R. Evenson, Jennifer A. Schrack, Daniela Sotres-Alvarez, Natasha Z. Anita, Yasmin Mossavar-Rahmani, Linda C. Gallo, Jordan A. Carlson, Matthew Allison, Martha L. Daviglus, Olga Garcia-Bedoya, Christina Cordero, Xiaonan Xue, Jianwen Cai, Kunihiro Matsushita, Robert C. Kaplan

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: This study assessed whether greater physical activity (PA) and lesser sedentary behavior (SB) reduce hospitalization risk equally among those with and without prediabetes, diabetes, or peripheral artery disease (PAD).

METHODS: We studied PA, SB and hospitalizations in 12,734 adults from the Hispanic Community Health Study/Study of Latinos, who were 52.2% female with mean (standard deviation) age 41.1 (14.9) yr at baseline. Participants reported 10,025 nonpregnancy-related hospitalizations (excluding emergency room only) over 13 yr. We modeled the association between accelerometer-measured activity (SB; light intensity physical activity [LPA]; moderate physical activity [MPA]; vigorous physical activity [VPA]) and hospitalization, using Andersen-Gill proportional …

Prediction Of Decline In Ovarian Function In Turner Syndrome., Roopa Kanakatti Shankar, Tazim Dowlut-Mcelroy

Manuscripts, Articles, Book Chapters and Other Papers

Comment on

• The role of hormonal markers in predicting reproductive lifespan in girls with Turner syndrome-a retrospective study. van der Coelen S, Sas T, Richter-Unruh A, Braat D, Fleischer K, Nadesapillai S, IntHout J, van der Velden J.J Endocr Soc. 2026 Jun 5;10(7):bvag122. doi: 10.1210/jendso/bvag122. eCollection 2026 Jul.PMID: 42272567 Free PMC article.

The Rise And Fall Of Lateral Electrical Surface Stimulation (Less) Through The Lens Of Srs Archives., Ali Rezazadeh Shirazi, Jay I. Kumar, Katie Dold, George H. Thompson, Andrew G. King, Richard M. Schwend, John P. Lubicky, Jay Shapiro, Behrooz A. Akbarnia, History Committee Of The Scoliosis Research Society

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Lateral electrical surface stimulation (LESS), commercially known as the ScoliTron™, emerged in the late 1970s as a noninvasive alternative to bracing for adolescent idiopathic scoliosis. Early clinical reports generated considerable enthusiasm and adoption, but the technique was ultimately abandoned. This study examined the rise and fall of LESS through a combined analysis of the Scoliosis Research Society (SRS) archives and published literature, with the goal of understanding factors that influence the adoption, evaluation, and abandonment of innovation in scoliosis care.

METHODS: A structured historical review was conducted using archival materials from the Scoliosis Research Society (SRS), including meeting abstracts, …

Pharmacogenetics In Pediatric Cardiology., Adenike Adenikinju, Jonathan B. Wagner, Mollie Walton

Manuscripts, Articles, Book Chapters and Other Papers

Children with congenital and acquired heart disease frequently require complex and prolonged pharmacotherapy, often involving off-label cardiovascular medications with narrow therapeutic ranges. Consequently, variability in drug response and medication-related adverse events remains a significant clinical challenge in pediatric cardiology. Pharmacogenetics provides a framework to individualize drug selection and dosing by incorporating genetic variability alongside established clinical and developmental factors. This review outlines the current clinical utility and emerging role of pharmacogenetics in pediatric cardiology, emphasizing applications most relevant to day-to-day patient care. Established pharmacogenetic associations with direct implications for pediatric cardiac practice include gene-drug pairs involving tacrolimus (CYP3A5), …

Parent-Child Neural Dynamics During A Stressful Task: Probing Associations With Temperament And Anxiety, Joscelin Rocha-Hidalgo, Harmony Nguyen, Dakota Reis, Denny Schaedig, Kahlil I Thompson, Susan B Perlman, Koraly E Pérez-Edgar

2020-Current year OA Pubs

Dynamic social interactions between parents and children can contribute to anxiety risk, amplifying shared genetic risk. Research has focused on observed behaviors to explain intergenerational transmission. Neural synchrony may contribute as a biological conduit for behavioral transmission of risk. We examined 109 parent-child dyads (

Perioperative Depression And Anxiety Care In Older Patients: A Randomized Clinical Trial, Joanna Abraham, Katherine J Holzer, Simon Haroutounian, Bethany Pennington, Ana Baumann, Ryan Calfee, Theresa Cordner, Kenneth E Freedland, Thomas Kannampallil, Benjamin Kozower, Emily Lenard, J Philip Miller, Mary Politi, Michael Yingling, Michael S Avidan, Eric J Lenze

2020-Current year OA Pubs

IMPORTANCE: Depression and anxiety are common among older adults undergoing surgery and are associated with adverse postoperative outcomes. However, effective tailored perioperative mental health interventions are lacking.

OBJECTIVE: To evaluate a perioperative intervention to optimize mental health.

DESIGN, SETTING, AND PARTICIPANTS: A single-blind, hybrid, type 1, effectiveness-implementation randomized clinical trial was conducted (November 1, 2022, to March 31, 2025), with 3-month postoperative follow-up, at a US academic and community practice hospital network. Participants were 60 years or older; scheduled for cardiac, oncologic, or orthopedic surgery; and had clinically meaningful symptoms of depression and/or anxiety based on the Patient Health Questionnaire-Anxiety …

Parents' Views On Family Care At A Neonatal Intensive Care Unit — A Qualitative Study, Linea Grothe Larsen, Suzanne Forsyth Herling, Sanne Allermann Beck, Anne Brødsgaard, Jos M. Latour, Rikke Louise Stenkjaer

School of Nursing and Midwifery

PurposeThe current study aims to explore parents' views on family care at a neonatal intensive care unit.MethodsWe conducted a qualitative exploratory study with a descriptive approach based on open-ended written narrative responses from the Danish version of EMpowerment of PArents in The Intensive Care—Neonatology questionnaire. The study was conducted at a Danish level IV NICU working with family-centred care and family integrated care. The data was analysed using inductive content analysis by Graneheim and Lundman. The Standards for Reporting Qualitative Research checklist was followed.Main FindingsIn total, 311/727 parents responded to the distributed questionnaire. Of those, 210 responded to the open-ended …

How Conditions Within Immigration Removal Centres In The United Kingdom Affect The Mental Wellbeing Of Detainees: A Scoping Review, Niamh Gallagher, Tristan Price, Matthew Griggs

Peninsula Medical School

BackgroundImmigration Removal Centres (IRCs) are used to detain people for immigration control by the UK government. This scoping review aims to examine the experiences of detainees within UK IRCs, specifically how conditions within them, including the regime, affect their mental wellbeing.MethodsThe Joanna Briggs Institute guideline for scoping reviews was followed. Six bibliographic databases and additional grey literature sources were searched for quantitative and qualitative evidence. Descriptive analyses and quality assessments were conducted.ResultsFifteen research studies and nine pieces of grey literature were included, comprising a total of 1353 participants and 11 IRCs. The majority of data was qualitative in methodology and …

Sexual Education And Sti Prevention In High School: A Neutrosophic Analysis Of The Opportunities And Risks Of Generative Artificial Intelligence, Antonio Pioquinto Rivera, Gregorio Nunez Hernandez, Rosalinda Villa Juarez

Neutrosophic Sets and Systems

Sexually transmitted infections (STIs) remain a critical challenge during adolescence. Given the limitations of traditional sex education, generative artificial intelligence (GAI) has emerged as a personalized and anonymous consultation alternative. This study analyzes, from a neutrosophic perspective, the scientific evidence published between 2019 and 2026 on the use of GAI to strengthen STI prevention among high school students. Through a critical integrative review of thirteen reference studies, a matrix was built that classifies the findings across four dimensions (AI-mediated learning, sexual education, STI prevention, and educational equity) according to their truth (T), falsity (F), and indeterminacy (I) components. The results …

Project-Based Learning And Mathematical Competencies In Primary Education: A Neutrosophic Cognitive Map Reading Of A Critical Integrative Review, Uriostegui Adan Yurithzi Majogani

Neutrosophic Sets and Systems

Developing mathematical competencies in primary school is essential for interacting with the environment. Faced with the limitations of traditional direct instruction, project-based learning (PBL) has emerged as an active alternative. This study analyzes, through a critical integrative review of ten reference studies (2016-2026), whether PBL determines the development of basic mathematical competencies in primary school students, and formalizes the resulting conceptual system as a neutrosophic cognitive map (NCM) with eight concepts and nine causal connections classified as positive, negative, or indeterminate. The static analysis of the map identifies PBL as the most central concept and makes explicit that the direct …

Taxi Geometry And Euclidean Geometry: Congruence And Similarity Of Triangles, Jose Carlos Pinto Leivas, Osvaldo Jesus Rojas Velazquez, Diana Carolina Perez Duarte, Randy Zabaleta Mesino

Neutrosophic Sets and Systems

This article presents an instrument that describes the experience implemented with students of a graduate programme in the courses of Analytic Geometry and Linear Algebra. The purpose of the instrument, as a didactic resource, was to analyse how the connections between the classical cases of congruence and similarity of triangles in Euclidean Geometry and in Taxi Geometry can be explored. The metric analysis of the productions shows that the three classical congruence criteria - SSS, SAS and ASA - cease to hold under the taxicab metric, and that equilaterality does not imply equiangularity in that geometry. In addition, a neutrosophic …