Digital Commons Network^™

Grant-O-Thon: A Designathon-Informed Grant Writing Program To Enhance Research Grant Writing Skills In Low- And Middle-Income Countries, Yusha Tao, Gifty Marley, Lauren Fidelak, Bin Yu, Yusuf Babatunde, Anita N. Walker, Anthony A. Attama, Andrea L. Conroy, Esther K. Afolabi, Dimitrios N. Vatakis, Iheanyi Omezuruike Okonko, Shyngle K. Balogun, Hongyun Fu, Xin Peng, Ijeoma M. Ifeorah, Patience Kukundakwe, Alexandra Cossio, Ifeoma M. Obionu, Ángela Patricia Beltrán López, Matthew Idowu Olatubi, Ucheoma C. Nwaozuru, Yuanyi Chen, Huachun Zou, Eneyi E. Kpokiri, Daniil Wu, Oliver Ezechi, Juliet Iwelunmor, Meredith Labarda, Jason J. Ong, Weiming Tang, Joseph D. Tucker

Department of Pediatrics Faculty Publications

Problem

Early career researchers in low- and middle-income countries (LMICs) face substantial barriers when writing research grants and have limited writing support. A designathon approach was applied to organize a grant writing workshop (grant-o-thon) tailored for early-career LMIC researchers. This study describes the planning, implementation, and participant-reported outcomes of the grant-o-thon as a participatory training approach.

Approach

Grant-o-thons were organized in 2023, 2024, and 2025. Consistent with the designathon model, the grant-o-thon was structured in three stages: preparation using co-creation with end-users, intensive collaborative teamwork supported by mentor feedback and weekly writing deliverables, and structured follow-up. Each grant-o-thon consisted of …

Red-Sensitive Photopolymerizable Glass For Fabrication Of Holographic Optical Elements, Jamshed Aftab, Izabela Naydenova, Tatsiana Mikulchyk

Research Outputs: 2025-Present

Water-resistant photopolymerizable glass, which represents a photopolymerizable hybrid sol–gel (PHSG) material, has emerged as a compelling platform for holographic optical elements fabrication (HOEs), owing to its exceptional mechanical and thermal robustness with high holographic recording performance. Until now, PHSG compositions have been limited to blue/green-sensitive systems, despite significant interest in extending sensitivity into the red spectral region. Here, we report the first holographic photopolymerizable glass with sensitivity to red light, achieved through the incorporation of methylene blue (MB) as a photosensitizer and N-phenylglycine (NPG) as a co-initiator, with an optimal MB/NPG ratio of 1:150. This PHSG composition is capable of …

A Dual-Domain Face Forgery And Deepfake Detection Framework, Neha Pradyumna Bora, Pradyumna Mulchand Bora, Rushikesh Sanjay Kumavat, Raunak Manoj Gangwal, Prit Sandesh Jain, Hardik Vijay Ostwal

Mansoura Engineering Journal

Concerns about media authenticity, privacy, and information security arising from rapid advances in deepfake technology have made it increasingly important to detect manipulated facial content reliably. The primary goal of our work was to develop a deepfake detection model with high generalization across multiple datasets. To achieve this, we developed a hybrid detection approach that combines spatial visual texture analysis and frequency-domain analysis to detect manipulated facial images. Our approach includes convolutional spatial feature extraction from facial images and frequency—domain representations of the same images obtained by applying the fast Fourier transform. To help alleviate concerns about overreliance on frequency—domain …

Effect Of Two Cut Off Rows On Seepage Underneath Hy-Draulic Structures Using Weak Form Differential Quadra-Ture Element Method: A Theoretical Approach, Esraa Ahmed, El-Masry A. A, Hossam A.A. Abdel Gawad, Ahmed Elhamrawy

Mansoura Engineering Journal

Investigating confined seepage underneath hydraulic structures is crucial to ensure the safety of these structures. The Weak Form Quadrature Element Method (WFQEM) is the basis of this paper, which explores the behavior of confined flow. The seepage flow governing equation is solved numerically to estimate the uplift pressure underneath the hydraulic structures and the exit gradient.The Gauss–Lobatto–Legendre (GLL) type is used as nodal and integration points. Several models were solved to validate the applied numerical method. The obtained results are compared with theoretical and preceding numerical solutions mentioned in the literature. The system of equations generated from applying the WFQEM …

Preserving The Identity Of Historic Coptic Orthodox Monasteries In Egypt Under Contemporary Pressures: Case Studies Of St. Bishoy And St. Anthony Monasteries, George Medhat Adeeb, Mohamed Khairy Amin, Mohamed Ahmed Al-Sherbiny

Mansoura Engineering Journal

Historic Coptic Orthodox monasteries in Egypt (HCOMEs) represent an important component of Christian heritage, integrating architectural value with enduring spiritual traditions that reflect both tangible and intangible dimensions. However, contemporary development and changing functional demands are generating transformations that may affect their identity if not carefully managed. Despite extensive scholarship, limited research has systematically examined these transformations through a structured evaluative approach. This study addresses this gap by developing and applying an analytical and evaluation framework to examine how contemporary pressures influence the historical, architectural-spatial, and spiritual identity of HCOMEs, and to assess the effectiveness of monastic responses. The framework …

Control Of Steel Corrosion Using Natural Corrosion Inhibitor, Rasha A. Nasef, O. Hamed, M. M. El-Halwany, M. H. Mahmoud

Mansoura Engineering Journal

This study investigates corrosion control of AISI 430 stainless steel in 1M HCl medium using an eco-friendly inhibitor extracted from pomegranate peel (PPE). The inhibition efficiency was evaluated at different PPE concentrations, with the highest applied concentration of 13g/L. Corrosion behavior was evaluated through weight-loss measurements and potentiodynamic polarization techniques conducted at room temperature.

The experimental results showed that corrosion resistance improved as the inhibitor  concentration increased. Lower corrosion rates were observed in the presence of PPE, along with reduced anodic and cathodic activities, indicating that the extract functions as a mixed-type inhibitor. Surface analysis confirmed the formation of …

Patent Law's Trade Remedy, Michael Doane

Akron Law Faculty Publications

Although a trade remedy, not an intellectual property rights statute, Section 337 of the Tariff Act of 1930 plays an important and controversial role in the enforcement of intellectual property rights in the United States. As a trade remedy, Section 337 is designed and intended to promote innovation and investment in the United States through support of statutorily defined domestic industries against unfair competition from infringing imported products. This Article analyzes Section 337 as a trade remedy from the perspective of intellectual property rights owners and innovators such as start-up companies, universities, individual inventors, and other research and development-focused entities. …

Just Prosecution, G. Ben Cohen

Akron Law Faculty Publications

Prosecutors were once envisioned as the heroes of the criminal legal system, wielding immense power to secure justice. Yet their role remained largely untethered to a coherent, principled framework. Without clear guardrails, traditional prosecution contributed to mass incarceration, racial disparities, and punitive excesses. Progressive prosecution sought to redress these deficiencies, but a lack of cohesive theoretical grounding, accompanied by a divestiture of power, left prosecutions weak. Reform was fragmented by electoral pressures but remained subject to abolitionist critiques. This article asks readers to consider the idea of Just Prosecution as a way of reimagining the prosecutor’s role—raising the question of …

Neurotensin Drives Theca Cell Migration During Ovulation In Primates, Jessica S. Miller, Megan A. G. Sage, Thomas E. Curry Jr., Diane M. Duffy

Department of Biomedical and Translational Sciences Faculty Publications

Theca cells are a critical steroidogenic cell type of the ovarian follicle and corpus luteum. The ovulatory luteinizing hormone (LH) surge (or human chorionic gonadotropin (hCG)) stimulates theca cell relocation from the stroma surrounding the dominant follicle to full integration into the developing corpus luteum. Luteinizing hormone/human chorionic gonadotropin also stimulates granulosa cells to produce local mediators of ovulation, including the peptide neurotensin (NTS). To determine if hCG-stimulated NTS regulates theca cell relocation within the ovulatory follicle, vehicle or an NTS receptor antagonist was injected into a macaque dominant follicle, and ovaries were removed 48 h after hCG administration. Additional …

P38 Mapk Is Involved In Epigenetic Regulation Of Fibrotic Genes In Replication Induced Senescence In Lung Fibroblasts, Shan Zhu, Jennifer Q. Zhou, Kan Wang, Ming-Lei Guo, Yan Sanders

Department of Biomedical and Translational Sciences Faculty Publications

Fibroblast activation is essential for tissue repair following injury; however, prolonged activation drives pathological fibrosis. Idiopathic pulmonary fibrosis (IPF), a progressive and age-associated lung disease, is characterized by aberrant fibroblast activation, with increasing evidence implicating senescent and near-senescent fibroblasts in its pathogenesis. However, the underlying mechanisms remain poorly defined. In this study, we investigated whether histone modification is involved in TGF-β1 treated lung fibroblasts and contributes to the fibrotic phenotype. Human IMR90 lung fibroblasts at low and high population doubling levels (LPDL and HPDL), as well as primary IPF fibroblasts, were used in this study. In response to TGF-β1, both …

Brief Pulses Of High-Level Fluid Shear Stress Enhance Metastatic Potential And Rapidly Alter The Metabolism Of Cancer Cells, Amanda N. Pope, Devon L. Moose, Guy O. Hudson, Hank R. Weresh, Marion R. Dykstra, Aabha Y. Joshi, Patrick Breheny, Eric B. Taylor, Michael D. Henry

Department of Biomedical and Translational Sciences Faculty Publications

Circulating tumor cells (CTCs) face challenges to their survival, including mechanical and oxidative stresses that are different from cancer cells in solid primary and metastatic tumors. The impact of adaptations to the fluid microenvironment of the circulation on the outcome of the metastatic cascade is not well understood. Here, we find that cancer cells exposed to brief pulses of high-level fluid shear stress (FSS) exhibit enhanced invasiveness and anchorage-independent proliferation in vitro and enhanced metastatic colonization/tumor formation in vivo. Cancer cells exposed to FSS rapidly alter their metabolism in a manner that promotes survival by providing energy for cytoskeletal remodeling …

Stat4-Dependent Regulation Of Neuroinflammation In Atherosclerosis, Natalie Stahr, Alina K. Moriarty, Shelby D. Ma, W. Coles Keeter, Woong-Ki Kim, Larry D. Sanford, Elena V. Galkina

Department of Biomedical and Translational Sciences Faculty Publications

Atherosclerosis is linked to an increased risk of cognitive decline, with chronic inflammation being a common feature of both pathologies. IL-12 activates STAT4 to regulate myeloid cell functions, and blockade of this pathway alleviates cognitive impairment in Alzheimer's models. However, the mechanisms connecting vascular pathology to neuroinflammation remain unclear. Here, we examine whether STAT4 functions as a common mediator of neuroinflammation in atherosclerosis. We demonstrate that LysM^Cre-specific STAT4 deficiency ameliorates deficits in long-term memory in low-density lipoprotein-deficient (Ldlr^-/-) mice fed a high-fat diet (HFD-C). STAT4 deficiency moderately reduces Ser199-phosphorylated Tau burden. Atherosclerosis alters brain immune …

The Interplay Between Loneliness, Cortisol, And Nk Cell Function: The Role Of Cortisol In Nk Cell Dysfunction, Abhinav Saurabh, Yvonne Baumer, Laurel G. Mendelsohn, Elizabeth M. Aquino Peterson, Dana Sadler, Shirley J. Lopez De Leon, Ayushi Dave, Andrew S. Baez, Lola R. Ortiz-Whittingham, Mario A. Pita, Manuel A. Cintron, Hannatu A. Tarfa, Sandy T. Reynolds, Shelby R. Hicks, Sonal Sharda, J. Eleanor Seo, Maria Lopez-Ocasio, Pradeep K. Dagur, Skyler A. Kuhn, Neelam R. Redekar, James F. Troendle, Ayanna L. Wells, Marie Marah, Katherine J. Tolentino, Michael J. Corley, Alika K. Maunakea, Lynnette K. Nieman, Marcus R. Andrews, Tiffany M. Powell-Wiley

Department of Biomedical and Translational Sciences Faculty Publications

Chronic psychosocial stressors contribute to cardiovascular disease (CVD) and related risk factors, particularly in under-resourced communities. Psychosocial stressors activate the hypothalamic-pituitary-adrenal (HPA) axis, leading to sustained cortisol action on immune cells. Natural killer (NK) cells are altered in distribution and function in cardio-metabolic diseases; however, pathways linking cortisol as a marker of chronic stress to NK cell dysfunction remain understudied. We recruited 186 African American women from the Step It Up Community-Engaged, Digital Health Physical Activity Intervention study and collected cortisol, NK cell measures, and psychosocial stress measures using validated questionnaires, including chronic stress and loneliness. Plasma cortisol levels were …

Revised Microbiology Core Knowledge Objectives For Modern Undergraduate Medical Education, Timothy J. Bauler, Cindy G. Arvidson, Samina Akbar, Dennis N. Arvidson, Margaret E. Bauer, Dwayne M. Baxa, Rebecca J. Greenblatt, Kerstin Honer Zu Bentrup, Yingguang Liu, Inaia Phoenix, Julie A. Kerry

Department of Biomedical and Translational Sciences Faculty Publications

Defining the core content for each scientific discipline in a modern preclinical medical education curriculum is critical to ensure optimal student learning and application of foundational knowledge for clinical practice. Attendees of the Association of Medical School Microbiology and Immunology Chairs (AMSMIC) Educational Strategies Workshop recently highlighted the need for updated medical microbiology learning objectives, given the shift in medical education toward less time for preclinical coursework and more integrated learning. Herein, we describe the process of developing a comprehensive, educator-driven set of knowledge objectives for medical microbiology. These objectives emphasize common pathogens, as well as pathogens associated with severe …

Cross-Cultural Communication Challenges In Multicultural Hospitality Teams: A Case Study Of The Arlington Hotel, Dublin, Lorrana Rosendo Da Silva

Business ETD Collections

This study investigates intercultural communication challenges within multicultural teams in the hospitality sector in Dublin, focusing on how linguistic barriers, cultural expectations and the dynamics of subgroups influence staff collaboration and day-to-day coordination. The research employs a qualitative case study at the Arlington Hotel, utilizing four semi-structured interviews—two with managers and two with employees—analyzed using thematic analysis. The findings indicate that, particularly during periods of high operational pressure, differences in English proficiency and understanding of accents can affect the clarity of instructions and the confidence to seek clarification. Furthermore, subgroups based on language or nationalities were described as useful in …

Key Factors Influencing Consumer Booking Decisions On Booking.Com, And The Role Of Trust In Online Reviews, Deisiane Soares

Business ETD Collections

This study examines the factors influencing accommodation booking decisions on Booking.com, with a particular focus on the role of trust in online reviews. Using a quantitative survey, the research analyses how consumers evaluate key factors such as price, location, ratings, and user-generated reviews. The findings show that while online reviews help reduce uncertainty and build trust, they are not the main driver of booking decisions. Instead, price and location are the most influential factors, with trust in reviews acting as a supporting element. Trust is also found to be conditional, depending on review consistency, detail, and recency. Hence, the study …

Exploring The Challenges Faced By Home Care Workers In Dublin, Camila Melo Dos Santos

Business ETD Collections

This study explores the challenges faced by home care workers employed by private healthcare providers in Dublin, and how the workers perceive the training and organisational support available to manage job demands. Using a mixed methods approach, quantitative data was collected through a survey that received 24 responses, and qualitative data from four in depth interviews. The findings identify time pressure as the most significant challenge, and discovered that formal training is available but it is not considered relevant by the workers, who rely on their experience to deliver the service. Organisational support was perceived as inconsistent, with lack of …

Member Engagement And Retention Challenges In The Latin Cycling Club Dublin, Sarideth Ailin Solis Lopez

Business ETD Collections

This study investigates participant engagement and retention challenges at Latin Cycling Club Dublin, a volunteer-run, non-profit community cycling group based in Dublin, Ireland. The group brings together Spanish-speaking people and others interested in Latin culture who ride together for hobby, social connection, and health improvement. Despite having 259 Instagram followers, 125 Strava participants, and 112 WhatsApp group members, only 8 to 12 people join rides on a regular basis, representing a drop-off of approximately 90 to 93%. The same small core group attends most rides, while the majority of followers remain inactive. Female participation is below 10%, and non-Spanish speakers …

Adapting International Marketing Strategies To Local Markets: A Case Study Of Zambrero In Ireland, Júlia Megale Freitas Pimenta

Business ETD Collections

As companies expand into increasingly globalised markets, they face the strategic challenge of balancing global standardisation with responsiveness to local market needs. This study examines how the balance between standardisation and local adaptation influences customer perception in the international fast-casual food sector. While standardisation can provide economies of scale, operational efficiency, and consistency in global brand identity, adaptation allows companies to respond to differences in consumer preferences, cultural expectations, and competitive conditions. Drawing on international marketing and branding literature, the study considers how these strategies influence perceptions of brand identity, authenticity, value, and customer loyalty across different national markets. Particular …

Country-Of-Origin Cues And Indian Consumers’ Skincare Purchase Intention: A Research Proposal For Reliance Retail’S Tira Beauty, Mohammed Ismail Shareef

Business ETD Collections

This study investigated how Indian consumers perceive the "country-of-origin" (COO) cue when evaluating skincare products from Tira Beauty. Specifically, this study focused on COO for both Indian-origin and foreign-origin skincare to determine if there is a link between origin, consumer trust in brands, attitudes toward brands, and intentions to make purchases. Using a qualitative methodology and three semi-structured online zoom interviews with Indian consumers who are familiar with Tira Beauty, the study identified themes within the interview responses and analysed them using manual thematic analysis in Microsoft Excel. Results indicate that COO influences initial perceptions of products; however, it does …

“I Don’T Always See A Future For Me Here”: Oppressive Political Pressures On Lgbtq+ College Students’ Well-Being, Jodi Linley, Olivia M. Copeland, Kathleen J. Buell, Cindy Ann Kilgo, Megan Pendleton, Alex C. Lange, N F. Tennessen

Journal of Queer and Trans Studies in Education

In recent decades, colleges have broadly supported LGBTQ+ students. Now, institutions have shuttered LGBTQ+ initiatives in response to political pressures, with little consideration for the effects on students. This study answers the question, what current policy factors do LGBTQ+ college students describe as affecting their well-being, and in what ways? We analyzed 426 responses from a multi-institution study of LGBTQ+ students. By and large, students feel anxious and fearful as they navigate the current climate. Our analysis illustrated numerous factors, from the President and his administration to states and general emboldened violence, and the real and potential consequences of those …

The Law Of Quitting, Andrew K. Jennings

Faculty Articles

Throughout life, people enter countless positions of authority and trust in relation to one another and the public. These positions include, among many others, being a public official, being a corporate director, and being an employee. Law announces prerequisites for starting such positions, as well as incumbents’ rights and obligations once in them. But no office holds forever. Indeed, incumbents often choose to exit positions before they would otherwise end by expiration, removal, or death. Yet law governs such voluntary relinquishment—often called “resignation” or, more generically, “quitting”—largely as afterthought. That is, law expansively attends how positions of authority and trust …

Managing Deportation: How Docket Control Replaced Substantive Relief In Immigration Courts, R. Linus Chan

SMU Law Review

In the modern deportation era, immigration courts saw their ability to grant relief from deportation undergo significant restrictions, constraining individualized discretion in favor of "categorical" denials. Congress dramatically curtailed the discretionary tools available to immigration judges, with the latest being the pair of immigration reforms from 1996, shifting the locus of individualized decision-making away from the courts and toward enforcement officers and prosecutors. Immigration courts lost discretion in being able to decide who could formally be granted status and stay in the United States when facing deportation through various restrictive eligibility requirements written into the law.

This Article argues that …

Fda After Loper Bright, Erika Lietzan

SMU Law Review

Loper Bright Enterprises v. Raimondo, which overruled the Chevron, U.S.A. v. Natural Resources Defense Council decision from 1984, tells us that a court should determine the meaning of all statutory provisions for itself, rather than deferring to the views of the federal agencies that implement those provisions. But the overruling of Chevron may have less of an impact on the U.S. Food and Drug Administration (FDA) than conventional wisdom supposes. Most challenges to FDA action do not concern its statutory interpretations. And the agency prevailed in most cases involving statutory interpretation before the Chevron doctrine took hold. After 1984, …

Health Communication Challenges In The Digital Era: Two Empirical Investigations, Neeraj Gautam Patel

Yale Medicine Thesis Digital Library

Background: The quality and availability of health information consumed by the general public have undergone dramatic changes in the 21st century with the rise of digitization and the internet. These include the growth of direct-to-consumer (DTC) advertising of prescription drugs on television and online media, changes in health content on traditional news media platforms, and the propagation of health misinformation and disinformation on social media and other websites. Understanding the nature and sources of these changes can inform efforts and interventions aimed at improving the general public’s understanding of health information. One area of interest within regulated health communication is …

Towards Developing A Career Technology Fit Framework And Analyzing Its Influence On Work-Related Outcomes Among It Professionals, Gunjan Tomer

Journal of International Technology and Information Management

With growing attrition rate and significant demand for skilled IT professionals, the importance of studying their behaviour has become important for both academia and industry. Despite ample amount of research, there is still a gap between theory and practice. Based on our qualitative study conducted on Indian IT professionals we propose that technology allocation might contribute in understanding the behaviour of IT professionals. We found that IT professionals evaluate the technology allocated to them based on their individual career motives. This evaluation, either positive or negative, influences their job outcomes. Further, we explored the factors that make a technology preferable …

High Technology And The Developing State: The Arrival Of Supercomputers In India, Ramesh Subramanian

Journal of International Technology and Information Management

While India has made vast strides in information technology in the last few decades, its success is mainly attributed to its software, rather than its hardware sector. In fact, India’s attempts at developing computer hardware that can match international standards have largely been unsuccessful. A notable exception is its development of a series of supercomputers that match and exceed many international standards. This paper looks at an interesting period in India’s computing history – namely the 1980s and 1990s – focusing on its development of an indigenous supercomputer. During that period, supercomputers were thought to be the sole privy of …

Responsible People Analytics For Remote-Work Decisions: A Machine-Learning Benchmark For Classifying Perceived Productivity, Ruth Menjivar, Nima Molavi, Narges Mashhadi Nejad

Journal of International Technology and Information Management

This study examines whether employee-perception survey data can support responsible people-analytics decisions about remote-work productivity. Using the public New South Wales (NSW) Remote Working Survey 2021 (N=1,512), the study benchmarks statistical and machine-learning classifiers for self-reported perceived productivity classes (same, less, or more productive when working remotely relative to onsite work), not objective output, under default, class-weighted, and resampling protocols. Main evidence comes from 5×5 repeated stratified cross-validation using macro F1 and balanced accuracy with fixed model specifications. Class-balanced separability is modest. Random Forest, CatBoost, and LightGBM form a leading cluster with overlapping confidence intervals (macro F1 ≈0.51–0.52). Affective/well-being items, …

The Value Of Personal Data Ecosystems: A Flemish Media Sector Case Study, Maarten De Mildt, Melanie Verstraete, Sofie Verbrugge, Didier Colle

Journal of International Technology and Information Management

Personal Data Stores (PDSs) have been proposed as a privacy-preserving approach to data sharing that increases individual control over personal data while enabling new forms of cross-organizational collaboration. This collaboration leads to the emergence of Personal Data Ecosystems (PDEs). Despite growing interest in PDEs, limited research has examined how the organizational and economic barriers identified in prior studies manifest in practice. This paper investigates these challenges through a case study of the Flemish media sector within the Solid4Media project, which explores the use of PDSs to support data sharing and personalization across media organizations. Using a qualitative research design, data …

The Deepfake Litmus Test: A Multimedia Authenticity Mechanism, Amna Alzaabi, Hessa Alqubaisi, Fatima Alzaabi, Richard Ikuesan

All Works

Deepfake technologies have made it increasingly difficult to distinguish authentic video content from manipulated media. This paper presents a forensic detection framework, referred to as the Litmus Test, which focuses on structural analysis of MP4 container files to detect signs of tampering. Unlike conventional AI-based approaches that operate as black boxes, this method examines the atomic composition of video containers to identify anomalies. The proposed method performs atom-level inspection of MP4 file hierarchies and structural markers to uncover anomalies indicative of synthetic manipulation. Evaluations using datasets such as CelebDF, UADFV, and DeeperForensics reveal that the framework can identify inconsistencies common …