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From The Archives: Houston's Pharmaceutical Past, Kelsey Koym

TMC Library Newsletter (2015-)

Step back into Houston's early pharmaceutical history with the McGovern Historical Center's newest collection, the Houston Drug Company Records.

Explore the story behind the collection and how these records found their way to the McGovern Historical Center: The Houston Drug Company Records

New Publishing Benefit For Tmc Authors: Mdpi, Joanne Romano

TMC Library Newsletter (2015-)

Publishing with MDPI? TMC-affiliated authors can now take advantage of new benefits through MDPI's Institutional Open Access Program (IOAP), including a discount on article processing charges (APCs) when publishing in MDPI journals.

Planning to publish? Learn more about the MDPI author benefit and how to take advantage of your TMC affiliation: Publishing Support at the TMC Library: MDPI

Heartland Virus Preclinical Research Project, Brian B. Gowen

Funded Research Records

No abstract provided.

Star Anise's Shield: How Illicium Verum Protects Dna From Oxidative Damage: An Integrated Experimental And Computational Study, Rafeef Amer Abdul-Jabar, Sabaa Ali Mohammed Al. Fadal, Anwar H. Ali

Baghdad Science Journal

Illicium verum, a star anise evergreen tree, is of great ethnopharmacological, medicinal, and biological interest. Objective: To develop an aqueous extract from its fruits and to evaluate its antioxidant potential, particularly in terms of DNA protection. The extraction method was straightforward; total phenolics (123 mg GAE/g) and flavonoids (51.3 mg QE/g) were quantified, and antioxidant (DPPH radical scavenging and iron (III) reducing) properties determined. The total antioxidant capacity (TAE) of the extract was estimated, and its protectiveness on human genomic DNA was examined. In addition, an in silico computer docking simulation was conducted to describe the molecular interactions of …

Monitoring Of Plankton And The Symbiosis In Maintaining Fertility In Tropical Water, Luthfiana Aprilianita Sari, Fio Surya Pratama Semendo Panhar, Naufal Falatehan, Fitrul Azizi Firdaus, Octavia Kartika Sari, Nurul Ashikin Abdullah, Felipe Polivanov Ottoni, Sulastri Arsad, Veryl Hasan, Syifania Hanifah Samara

Baghdad Science Journal

Plankton serve as live food for aquatic organisms and are indicators of water fertility, which is related to its abundance and diversity. Some live feeds also form a symbiotic relationship with macroalgae, known as epiphytic plankton, which is found in estuarine waters. The Brondong estuary area, Brondong District, Lamongan, East Java, with abundant Caulerpa sp. macroalgae, exemplifies these characteristics. This study aimed to identify the abundance, diversity, uniformity, and dominance indices of zooplankton, epiphytic microalgae, phytoplankton, and chlorophyll a in the Brondong estuary. Given that research on identifying epiphytic plankton species attached to Caulerpa sp. is lacking, this study investigates …

Diagnostic Assessment Of Blood Parasites In Tick-Infested Horses (Ixodidae In Iraq: A Comparative Survey Between Microscopic Inspection And Elisa Technique, Wasan Addai Al-Marsomy

Baghdad Science Journal

Ticks (Ixodidae) are a major vector for many parasites that cause considerable diseases in horses; the most prominent are tick fever or bloody urine fever, which is caused by Babesia or Piroplasmosis, which is found inside red blood cells, leading to blood loss or hemolytic anemia, or Theileria parasite, affecting lymphocytes and erythrocytes, and other parasites, such microorganisms negatively impact in immunity of equines. This study involved the collection of blood samples (75) from horses; samples were divided into two groups: the first group (40) cases infested with a tick parasite and the second group (35) healthy horses. Specimens were …

Dung Removal And Tunneling Contributions: Ecomorphological Traits And Functional Performance Of Onthophagus Gazella And Onthophagus Ramosellus, Takhmina Nazir, Mubashar Hussain

Baghdad Science Journal

Dung beetles perform various functions in ecosystems, such as nutrient cycling, aeration of soil, and dung burial activities that increase soil properties. Genus Onthophagus is well known for its role in dung removal and decomposition. We appraised the role of Onthophagus ramosellus and Onthophagus gazella in dung removal under field conditions. Species-specific functional features like body size and dry body weight associate these dung beetle species with tunneling depth and dung removal. We installed mesocosms (18 cm height and 12 cm diameter) at three sites in district Gujrat, i.e., Chak, Chopala, and Kot Mir Hussain. Treatment groups used in the …

Phytochemical Screening And Antioxidant Potential Of Glycyrrhiza Glabra L. Extract And Silver Nanoparticles Against Aspergillus Spp., Sakar Abdulqadr Saheed, Badr Qader Ismael

Baghdad Science Journal

Medicinal plants continue to be a source of antifungal agents, and the green synthesis of nanoparticles has enhanced the bioactive potential of Glycyrrhiza glabra L. In the present study, ultrasonic-assisted chloroform- and ethanol-extracted leaves & roots were prepared, whereas aqueous extracts were used for green synthesis of Ag NPs. Phytochemical evaluation of the extract showed the availability of terpenoids, phenols, flavonoids, tannins, saponins, and resins. Formation of Ag NPs was confirmed by a UV–Vis plasmon resonance peak at 400–438 nm, FT-IR functional groups (O–H, C=O, and C–N), spherical morphology from FE-SEM, EDX signal of silver atoms, and fcc planes in …

Molecular Characterization And Genotypic Distribution Of Hepatitis B Virus Isolates In Iraq: Prevalence Of Drug Resistance Mutations, Omar Hamid Salman, Raghad Harbi Al-Azzawi

Baghdad Science Journal

Hepatitis B virus (HBV) remains one of the most pervasive viral threats worldwide, posing a significant risk to millions. Due to the absence of proofreading activity during reverse transcription, HBV exhibits a high genetic variability. To date, ten distinct HBV genotypes have been identified globally, associated with varying disease outcomes, including progression to cirrhosis and carcinoma, as well as responses to antivirals. Consequently, genotypic analysis and molecular characterization of HBV are critical for optimizing therapeutic strategies. This study aimed to investigate the distribution of HBV genotypes among Iraqi patients and to characterize their molecular profiles. Therefore, a modified protocol was …

Probable Renal-Limited Sarcoidosis Presenting With Tubulointerstitial Nephritis Without Granulomas On Renal Biopsy: A Diagnostic Challenge, Jawahar Hamood Alnoumani, Muhammad Shoaib, Asma Marzouqi, Ali Al Lawati

Sultan Qaboos University Medical Journal

Sarcoidosis is an idiopathic multisystem inflammatory disorder characterised by non-caseating granulomas and a wide range of reported prevalence. Renal-limited sarcoidosis is a rare manifestation of sarcoidosis which remains a diagnostic challenge due to lack of extra renal manifestation and specific diagnostic criteria. We report a 37-year-old man who presented to a tertiary care hospital, Muscat, Oman, in 2024, with a two-month history of fever, weight loss, hypercalcaemia, high-to-normal 1,25-Vitamin D, high angiotensin-converting enzyme levels and acute kidney injury. His renal biopsy showed evidence of tubulointerstitial nephritis without granulomas or nephrocalcinosis. After exclusion of infectious, malignant, drug- related and autoimmune causes, …

The Cul-De-Sac Paradox: The Relationship Between Walkability, Playability, And Children’S Physical Activity, Lydia Reader

McKelvey School of Engineering Graduate Student Theses & Dissertations

Walkability and playability are two constructs on how the built environment can support physical activity, the former most relevant to adults and the latter designed with children in mind. There are concerns that walkability and playability are intrinsically in competition with one another, with urban forms supportive of physical activity for adults detrimental toward the physical activity of children and vice versa. This thesis explores this conflict using agent-based modeling as a tool for refining the theoretical constructs behind playability and children’s physical activity. We examine the state of the current evidence for the relationship between walkability and children’s physical …

Data-Driven Staging Of Neurodegenerative Pathology Related To Alzheimer’S Disease, Thomas Earnest

McKelvey School of Engineering Graduate Student Theses & Dissertations

Alzheimer’s Disease (AD), the most common cause of dementia, is a dual proteinopathy exhibiting deposits of extracellular amyloid-beta (Aβ) and intracellular tau in brain tissue. Models which describe the spatial and temporal trajectories of these pathologies have been invaluable for understanding AD and have the potential to support diagnosis, disease monitoring, and treatment development. Disease staging systems, which provide protocols for assessing individual disease severity based on their extent of brain pathology, have been crucial for explaining and diagnosing AD. However, these systems have been primarily informed by post-mortem histological assessments and are not directly applicable to disease assessment in …

Dissecting Tumor Evolution And Immune Composition In Prc2 Loss (H3k27me3 Loss) Vs Retained Mpnst, Kuangying Yang

Arts & Sciences Graduate Student Theses and Dissertations

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise sporadically or in the setting of neurofibromatosis type 1 (NF1). Although benign plexiform neurofibromas (PNs) are common in NF1, only a subset undergo malignant transformation, and the molecular events that define high-risk progression remain incompletely understood. A major axis of biological heterogeneity in MPNST is loss of Polycomb Repressive Complex 2 (PRC2), commonly detected through loss of H3K27me3 and frequently mediated by alterations in SUZ12 or EED. This dissertation integrates three manuscript-based studies to define genomic resources, tumor-intrinsic vulnerabilities, and immune microenvironmental remodeling in NF1-associated peripheral nerve sheath tumors, …

Exploring Wearable Technology In Freshmen High School Physical Education: Effects On Engagement And Enjoyment, Danielle Madrid

Doctorate in Kinesiology

Wearable technology offers physical educators a potential tool for providing real-time feedback and supporting student engagement during physical activity. This mixed-methods study examined the influence of Polar A370 wearable fitness trackers on enjoyment and engagement among 99 ninth-grade students enrolled in high school physical education. During a two-week within-subject crossover intervention, students alternated between participating in physical education lessons with and without wearable technology. Physical activity enjoyment was assessed before and after the intervention using the Physical Activity Enjoyment Scale (PACES), while a researcher-developed supplemental survey, open-ended responses, and observational field notes provided additional information regarding students’ motivation, engagement, and …

Risk Assessment And Sentencing Bias: The Role Of Socioeconomic Status And Mental Health, Lily A. Walsh

Student Theses

The current research examined the impact of risk assessment information in the sentencing of defendants of varying socioeconomic statuses (SES), and mental health statuses. A US sample of students studying law (N = 137) was assigned to view one of eight vignettes that manipulated the defendants SES (i.e., low or high), mental health status (i.e., schizophrenia diagnosis or no diagnosis), and the availability of risk data (i.e., present or absent). Participants sentenced the defendant to probation, short-term jail, or prison, and indicated the sentence length in years. An Ordinal Logistic Regression and a Three-way Factorial ANOVA indicated neither the availability …

Poppers Maculopathy Due To Alkyl Nitriteinfused Candle: A Case Report, Tori Sayers, Murtaza K. Adam

School of Medicine Publications

Recreational inhalation of alkyl nitrites (“poppers”) is associated with a characteristic toxic maculopathy presumably due to ischemic changes in the central macula. Alkyl nitrite candles are available for purchase online and do not appear to be regulated. We report a unique retrospective case of vision loss following second-hand inhalation of vapor from a “poppers” candle in which a 29-year-old Hispanic male with no previous medical history presented with acute bilateral vision loss after attending a party at a nightclub. The patient denied sungazing, exposure to lasers, and a family history of inherited retinal disease. History was significant for use of …

Retaining Teaching Hospital Nonacademic Nurse Educators: Addressing Burnout And Building Workforce Resilience, Walter Guevara

Walden Dissertations and Doctoral Studies

Burnout and high turnover intentions among nonacademic nurse educators (NANEs) in academic teaching hospitals pose a critical challenge for healthcare administration, threatening workforce stability, nursing education capacity, and healthcare outcomes. The purpose of the integrative review was to examine evidence-based strategies to reduce burnout and enhance resilience among NANEs, thereby improving retention, well-being, and workforce sustainability. An integrative literature review was conducted using the Johns Hopkins Evidence-Based Practice appraisal tools and 49 sources published between 2020 and 2025 were found to match criteria and quality for thematic analysis. Guided by Herzberg’s two-factor theory, a thematic analysis was used to synthesize …

Staff Education On Improving Medication Adherence, Oneil Dobgima Galega

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project addressed a practice gap in an outpatient behavioral health setting involving inconsistent use of structured communication strategies to support medication adherence among psychiatric patients. Although nurses routinely provided medication instructions, approaches such as motivational interviewing and psychoeducation were underutilized, limiting patient engagement, understanding, and adherence, and ultimately affecting care continuity and outcomes. The purpose of the project was to improve psychiatric nurses’ knowledge and intent to use motivational interviewing and psychoeducation to enhance medication adherence. The guiding practice-focused question examined whether a structured educational intervention could strengthen nurses’ competencies in these communication strategies. …

Staff Education To Improve Consistent Phq-9 Administration In An Outpatient Psychiatric Practice, Ngozi Eboru

Walden Dissertations and Doctoral Studies

Depression is a leading cause of disability and is associated with functional impairment, reduced quality of life, and increased healthcare utilization. Consistent administration of the Patient Health Questionnaire-9 (PHQ-9) is an essential component of measurement-based care, supporting the identification, monitoring, and treatment of depressive symptoms. A retrospective chart review at a private outpatient psychiatric practice identified inconsistent PHQ-9 administration and documentation, with a baseline completion rate of 62%. The purpose of this Doctor of Nursing Practice staff education project was to evaluate the impact of a structured educational intervention on the consistency of PHQ-9 administration among staff involved in the …

Strategies For Managing Change In Home Health Care Businesses, Halbert Brown

Walden Dissertations and Doctoral Studies

Home health care agencies may experience financial hardship when regulatory inspections result in deficiencies and administrative penalties. Home health company (HHC) leaders are concerned because ineffective change management strategies may contribute to ongoing regulatory deficiencies, penalties, and reduced business performance. Grounded in Lewin’s change management theory, the purpose of this qualitative pragmatic inquiry project was to explore change management strategies some HHC owners successfully implemented to reduce administrative deficiencies and penalties to augment business performance and profitability. The participants were six leaders from HHC firms in the southwestern region of the United States who had developed effective strategies to improve …

Staff Education To Improve Nursing Knowledge On Pressure Injury Prevention, Kheeda Kimberly Gopaul

Walden Dissertations and Doctoral Studies

Staff education in this project was focused on improving nursing staff’s knowledge on pressure injury prevention, inspired by the persistent care quality gap. The gap in practice as of 2024 related to hospital-acquired pressure injury (HAPI) at the host health organization was reported to be approximately 0.2 per 1,000 discharges. It was apparent that education could benefit the nursing staff to improve their knowledge in pressure injury prevention. The education in service focused on continuous nursing skin assessments, to ensure over prolonged hospitalization, patients’ skin does not deteriorate with the development of pressure injuries or advancing of pre-existing pressure ulcers. …

Exploring The Experiences And Support Needs Of African Immigrant Families Raising Children With Autism Spectrum Disorder In Ohio, Linda Nkoumba Eteki

Walden Dissertations and Doctoral Studies

Autism spectrum disorder (ASD) presents unique challenges for families; however, African immigrant parents raising children with ASD in Ohio experience additional difficulties related to cultural stigma, systemic inequities, and limited access to culturally responsive services. This social work practice problem is important because it reflects disparities in diagnosis, intervention, service access, and family support that align with social work’s commitment to equity, advocacy, and social justice. The purpose of this qualitative study was to explore the experiences of African immigrant families raising children with ASD in Ohio and to examine how they describe autism-related stigma, caregiving challenges, and interactions with …

Staff Education To Improve Central Line Maintenance Documentation Compliance, Martha Danette Oglesby

Walden Dissertations and Doctoral Studies

This was a staff education quality improvement project aimed at improving compliance with central line maintenance documentation among nurses on a busy transitional care unit (TCU). The practice problem was inconsistent documentation of central line bundle documentation. Documentation is an important part of nursing care and is the most effective way to communicate the care provided. Effective documentation is a pivotal way of identifying evidence-based care to prevent central line-associated bloodstream infections (CLABSIs). The practice-focused question was, In nursing staff working on an inpatient TCU, what is the impact of targeted education on evidence-based central venous catheter bundle care documentation, …

Lived Experiences Of Clinical Psychologists: Personal Coping Strategies To Address Emotional Exhaustion, Ayushi Shrestha

Walden Dissertations and Doctoral Studies

Emotional exhaustion is a key element of burnout among clinical psychologists. However, there are limited qualitative studies that examine how psychologists experience and cope with it. This study explored how licensed clinical psychologists experience and cope with emotional exhaustion. The study used Orem’s Self-Care Deficit Theory to explore how clinicians perceive, interpret, and respond to emotional demands. Semi structured interviews with licensed clinical psychologists experiencing emotional exhaustion were used to collect data. Data were analyzed using an interpretative phenomenological analysis approach, including descriptive and pattern coding to identify themes. Five themes were identified: workplace and organizational stressors; emotional experience of …

Relationship Between Sociodemographic Factors And Opioid Overdose Mortality In Milwaukee County, 2020-2021, Elizabeth David

Walden Dissertations and Doctoral Studies

Opioid overdose deaths increased significantly from 2020 to 2021, with Milwaukee County experiencing higher rates than the national and state averages. African American and Hispanic residents faced disproportionately high fatal overdose rates. The purpose of this quantitative retrospective cross-sectional study was to examine the associations among socioeconomic status, race, age, access to treatment (measured by emergency medical services [EMS] naloxone administration), and opioid overdose mortality among underserved minority populations in Milwaukee County. Guided by the social-ecological model, the study analyzed data from the Milwaukee Health Department and the Milwaukee County Medical Examiner's Office across 34 ZIP codes. Inclusion criteria for …

Openness To Experience And Creative Capacity Among Active First Responders, William Reagan

Walden Dissertations and Doctoral Studies

Because emergency services demand adaptive, creative problem-solving within procedurally rigid cultures, this study examined whether Openness to Experience predicted creative capacity among active first responders and whether age or tenure moderated that relationship. A cross-sectional design used N = 117 first responders from eight agencies. Openness was measured with the Big Five Inventory-2 (percentile ranks); creativity was assessed with the Divergent Association Task (DAT; n = 116) and the Consensual Assessment Technique (CAT; n = 111). Covariates were age, tenure, rank, gender, and, for 46 participants at one agency, a dispatch-derived operational exposure score. In the full sample, Openness did …

Addressing Implicit Bias Toward Patients With Substance Use Disorders Through A Staff Education Quality Improvement Initiative, Jeanne Baleng Okuwobi

Walden Dissertations and Doctoral Studies

This doctoral project was a staff education quality improvement (QI) initiative designed to reduce implicit bias among healthcare providers toward patients with substance use disorder (SUD) at a community mental health center. Provider implicit bias toward patients with SUD contributes to stigma, inequitable care, reduced treatment engagement, and poorer health outcomes; addressing this bias is essential to advancing patient safety, health equity, and quality nursing care. The practice-focused question guiding this project asked whether a 9-week evidence-based staff education program incorporating didactic instruction and reflective practice would reduce provider implicit bias toward patients with SUD compared with current practice, which …

Mexican Women Caregivers’ Support For Family Members With Type 2 Diabetes, Andrea Mesa

Walden Dissertations and Doctoral Studies

Type 2 diabetes (T2D) is a persistent public health challenge in the United States, disproportionately affecting Hispanic populations. Mexican-origin women often serve as primary caregivers for relatives living with diabetes, yet their voices and lived experiences remain underrepresented in research. This study addressed the limited understanding of how cultural values and caregiving roles influence diabetes management within Hispanic families. The purpose of this qualitative phenomenological study was to explore the lived experiences of Mexican-origin women aged 40 to 60 who care for a family member with T2D. Guided by the theory of planned behavior and social cognitive theory, the study …

Sbirt Staff Education To Registered Nurses In The Emergency Department, Rosemary Thuet

Walden Dissertations and Doctoral Studies

Summary The project hospitals have, on average, 2,400 emergency department (ED) visits a month. Although patients receive a social screening, there are no specific assessments to determine if the person is at risk for alcohol use disorder (AUD). The lack of screening is a missed opportunity to provide a Screening, Brief Intervention and Referral to Treatment (SBIRT) assessment of over 2,400 patients a month or 48,000 people annually. Although several screening tools could be used for an SBIRT assessment, the recommendation of ED nursing leadership is to implement the tool known as the CAGE Questionnaire (Cut down, Annoyed, Guilty, and …

Staff Education To Improve Behavioral Health Integration In Primary Care, Nelly Endah Atu

Walden Dissertations and Doctoral Studies

This staff education project addressed a persistent gap in the delivery of integrated physical and mental healthcare for patients with co-occurring conditions. Fragmented care in primary care contributes to untreated mental health needs, increased patient distress, higher costs, and poor outcomes. The aim of this project was to develop, deliver, and evaluate a staff education program equipping nurses, nurse practitioners, and interdisciplinary team members with the knowledge, skills, and practical strategies needed to improve behavioral health integration in primary care. The practice question was, among interdisciplinary staff in a community health setting, did the implementation of an evidence-based, ADDIE-designed staff …