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Articles 4591 - 4620 of 1791776
Full-Text Articles in Entire DC Network
Development Of Minimalist Trifunctional Building Blocks For Chemical Biology Probe Synthesis, Luke E. Bohrer
Development Of Minimalist Trifunctional Building Blocks For Chemical Biology Probe Synthesis, Luke E. Bohrer
Electronic Theses and Dissertations
The completion of the Human Genome Project in 2003 generated expectations that genomic information would accelerate the discovery of new protein drug targets and FDA-approved therapies. However, many small-molecule drug candidates continue to fail in clinical trials, and much of the human proteome remains undercharacterized in terms of structure, function, and disease relevance. Chemical tools are therefore essential for defining protein function, mapping protein interactions, and identifying disease-associated molecular mechanisms. Among these tools, small-molecule chemical probes provide a powerful strategy for connecting biological activity with target identification, functional analysis, and the development of effective therapies.
This dissertation describes the development …
Impact Of Taped Problems Intervention Modification On Children With Deafness, Clyniece Hodge
Impact Of Taped Problems Intervention Modification On Children With Deafness, Clyniece Hodge
Electronic Theses and Dissertations
Children with hearing loss are at an increased risk of experiencing setbacks in various areas of life, including academic performance and employment opportunities. Academically, they are likely to experience poor academic achievement in reading, as well as in mathematics (ASHA, 2013). In comparison to gifted hearing students and average-ability hearing students, students with hearing loss are at a higher risk of low mathematics performance (Hassan & Mohammed, 2019). Despite these known challenges and risk factors, limited research has been conducted to identify effective intervention strategies for improving mathematical outcomes among this population. As such, this study aimed to evaluate the …
Integrating Naturalistic Developmental Behavioral Interventions In Inclusive Classrooms To Support Autistic Students, Paige J. Johnson
Integrating Naturalistic Developmental Behavioral Interventions In Inclusive Classrooms To Support Autistic Students, Paige J. Johnson
Electronic Theses and Dissertations
The current trend of an increasing prevalence rate of autism spectrum disorder creates a growing need for evidence-based interventions that can be accessed in the natural environments, such as within inclusive educational settings. Naturalistic Developmental Behavioral Interventions (NDBIs) integrate principles of applied behavior analysis and developmental psychology, and offer effective tools for increasing social communication behaviors in autistic children that align with the neurodiversity-affirming movement. The present study sought to evaluate the effectiveness of Behavior Skills Training (BST) in teaching core NDBI skills to a preschool teacher, examine changes in teacher self-efficacy related to supporting autistic students, and assess the …
A Mixed-Methods Pilot Study Of A 10-Week Wellness Program For Resident Assistants, Emily L. Lee-Chong
A Mixed-Methods Pilot Study Of A 10-Week Wellness Program For Resident Assistants, Emily L. Lee-Chong
Electronic Theses and Dissertations
This mixed-methods pilot study used semi-structured interviews with 15 resident assistants (RAs), complemented by descriptive pre- and post-test data from the Five Factor Wellness Inventory (FFWEL), to explore their lived experiences of participating in a 10-week wellness program grounded in the Indivisible Self Model of Wellness (IS-WEL). The purpose of this study was to examine the program's perceived influence on wellness practices and to explore the feasibility of implementing wellness-focused programming. Using a hermeneutic inquiry approach, the study identified four themes reflecting participants’ experiences throughout the program. Themes highlighted the importance of self-awareness through the IS-WEL model, the value of …
Race And Trauma: An Analysis Of Trauma Symptomology Across Diverse Youth Populations, Mara J. Niccoli
Race And Trauma: An Analysis Of Trauma Symptomology Across Diverse Youth Populations, Mara J. Niccoli
Electronic Theses and Dissertations
The adverse effects of trauma, particularly among youth who identify as Black, is a critical issue. This study investigated the relationship between race and trauma symptomology among children and adolescents who received weekly trauma therapy. With the use of clinical assessment data, this study sought to determine whether Black youth presented to treatment with higher trauma acuity than non-Black youth and if there were disparate outcomes in symptomology after treatment. The results indicated that on average, Black youth presented to treatment with lower trauma acuity than non-Black youth, and there were disparate outcomes in trauma symptomology between the two racial …
A Philosophy Of Communication Response To Bullying In Corporate America, Chris A. Phillips Dr.
A Philosophy Of Communication Response To Bullying In Corporate America, Chris A. Phillips Dr.
Electronic Theses and Dissertations
This philosophy of communication response to bullying in corporate America follows the structure of posing research questions, synthesizing relevant literature, and offering advice to practitioners. It invites the reader to have hope in continuing the conversation through a constructive hermeneutic approach to the problem. By building on literature in oppression, silencing, bullying, incivility, and communication ethics, this dissertation reveals how (rhetoric) and why (philosophy) the problem occurs in corporate America today. This dissertation offers a new angle to an old problem, or, a rhetoric and philosophy of bullying. It responds to the following questions:
RQ 1: As a destructive communication …
Between Care And Despair: An Existential Phenomenological Study Of Eco-Anxiety As Lived Experience, Conor H. Sukhdeo
Between Care And Despair: An Existential Phenomenological Study Of Eco-Anxiety As Lived Experience, Conor H. Sukhdeo
Electronic Theses and Dissertations
This dissertation explores the lived experience of eco-anxiety among young adults aware of the ongoing ecological crisis but not directly exposed to climate-related disasters. Grounded in the human science tradition, ecopsychology, and existential phenomenology, this study employed Scott Churchill’s (2022) approach to Existential Phenomenological Research (EPR) to deepen our understanding of the phenomenon of eco-anxiety. Four participants, residing in Pittsburgh and aged 18-25, produced written experiential descriptions and participated in open-ended phenomenological interviews. As outlined by EPR, this data was analyzed through meaning unit delineation, imaginative variation, phenomenological reduction, and structural synthesis to produce individual situated structures of eco-anxiety for …
Empathetic Political Communication As The Political Identity Of Female Legislators: A Phenomenological Study In The Surabaya City Dprd, Nurannafi Farni Syam Maella, Farida Farida, Herlina Harsono Njoto, Hamizah Sahharon, Vinna Amalia
Empathetic Political Communication As The Political Identity Of Female Legislators: A Phenomenological Study In The Surabaya City Dprd, Nurannafi Farni Syam Maella, Farida Farida, Herlina Harsono Njoto, Hamizah Sahharon, Vinna Amalia
JURNAL KOMUNIKASI INDONESIA
Politics has long been constructed as a masculine arena dominated by discourses of power, authority, and instrumental rationality. The presence of female legislators disrupts this hegemony by foregrounding empathetic modes of political communication that emphasize inclusivity, relational engagement, and responsiveness to social realities. These communicative practices not only contest dominant masculine norms in political discourse but also expand deliberative spaces and support the formulation of gender-responsive public policies. Accordingly, this study examines how female legislators in the Surabaya Legislative Council construct and enact empathetic political communication as a core expression of their political identity. Using a qualitative phenomenological approach, this …
Alma Matters April - June 2026 Vol. 01 Issue 02, Aga Khan University Alumni Association
Alma Matters April - June 2026 Vol. 01 Issue 02, Aga Khan University Alumni Association
The Aga Khan University Newsletter and Magazine for Alumni (AKU-NAMA)
- Advancing Healthcare Through Global Collaboration
- AKU and Sindh Govt Launch Historic Nursing Partnership
- New Dean for Faculty of Arts and Sciences
- AKU Showcase Explores AI in Research for Global Impact
- Aga Khan University and LUMS Forge Strategic Partnership
- Alumni Affairs Launches ‘AKU Connect’ – A Mentorship Platform for Students
- The Power of Alumni Giving
- Gift Signing Ceremony with AKU MBBS Class of ‘05
- NEWS , HIGHLIGHTS AND UPDATES
- AKU ENTITIES
Cultivating Young Naturalists: Developing A Junior Master Naturalist 4-H Special Interest Club In Cook County, Il, Matthew M. Stinson
Cultivating Young Naturalists: Developing A Junior Master Naturalist 4-H Special Interest Club In Cook County, Il, Matthew M. Stinson
Capstone Projects – Politics and Government
This capstone researches the development, implementation, and evaluation of a Junior Master Naturalist (JMN) 4-H Special Interest (SPIN) Club, a pilot environmental education program for high-school students in South Suburban Cook County, Illinois. Through a partnership among University of Illinois Extension – Serving Cook County, the Forest Preserves of Cook County, and the Friends of the Forest Preserves, JMN addressed two goals: increasing 4-H participation and engagement among high-school aged youth and encouraging high-school aged participation in local forest preserves spaces. Grounded in research on positive youth development, 4-H youth development, and environmental education, the program provided hands-on, place-based learning …
Large-Scale Dna Barcoding Reveals Highly Distinct Insect Distribution Patterns Across Costa Rican Ecosystems, José A. Hernández Ugalde, Daniel H. Janzen, Winnie Hallwachs, Bert Kohlmann, Paul D.N. Hebert, Brian V. Brown, James Whitfield, José. L. Fernández-Triana, Roberto Fernández Ugalde, Eugenie Phillips Rodriguez, Ronald Zúñiga, M. Alex Smith, Dirk Steinke, Michael Sharky, Donald Quicke, Ramya Manjunath, Robert Puschendorf
Large-Scale Dna Barcoding Reveals Highly Distinct Insect Distribution Patterns Across Costa Rican Ecosystems, José A. Hernández Ugalde, Daniel H. Janzen, Winnie Hallwachs, Bert Kohlmann, Paul D.N. Hebert, Brian V. Brown, James Whitfield, José. L. Fernández-Triana, Roberto Fernández Ugalde, Eugenie Phillips Rodriguez, Ronald Zúñiga, M. Alex Smith, Dirk Steinke, Michael Sharky, Donald Quicke, Ramya Manjunath, Robert Puschendorf
School of Biological and Marine Sciences
Although insects are fundamental to understanding and conserving global biodiversity, they are vastly understudied. Here, we present a national inventory of Costa Rican insects based upon 3.78 million DNA barcodes representing 152 891 Barcode Index Numbers (BINs, proxies for species) from 28 localities sampled from 2017 to 2023 through the national BioAlfa program of Costa Rica. Although only 3.6% of BINs are linked to Linnean species, barcode-based community analyses revealed strong, consistent ecogeographic structure. Clustering of BIN data using bootstrapped Jaccard distances revealed seven distinct mainland assemblages and a distinct island cluster, shaped primarily by Costa Rica’s mountain ranges, elevation, …
“No Te Metas, Eso Es De Hombres”: How Gendered Barriers Shape Women’S Income And Success In Rural Mexico’S Livestock Sector, Sofia Gaeta Garcia
“No Te Metas, Eso Es De Hombres”: How Gendered Barriers Shape Women’S Income And Success In Rural Mexico’S Livestock Sector, Sofia Gaeta Garcia
McNair Summer Research Program
Women play a significant role in Mexico’s livestock sector, contributing to production, breeding, animal care, and local market activity. However, their labor is often overlooked and undervalued. Women’s work is often treated as “help” rather than recognized as real labor. The calls for “No te metas, eso es de hombres” and “La mujer ayuda, el hombre decide” reflect the gendered ideas this project examines. This research argues that financial, structural, and cultural barriers limit women’s participation in rural Mexico’s livestock industry by restricting their access to income, resources, decision-making power, and financial independence. Using a qualitative research design, this project …
Outbound Tourism – A Cluster Analysis Of Indian Travellers Based On Travel Motivation And Preferences, Shweta Belwal, Rakesh Belwal, Zoe Morgan, Latifa Hamood Al Badi
Outbound Tourism – A Cluster Analysis Of Indian Travellers Based On Travel Motivation And Preferences, Shweta Belwal, Rakesh Belwal, Zoe Morgan, Latifa Hamood Al Badi
Plymouth Business School
PurposeThis study aims to explore the travel motivations and preferences of Indian outbound tourists, segmented by motivation and sociodemographic traits.Design/methodology/approachUsing a quantitative research approach, the study administered a structured questionnaire via SurveyMonkey to potential Indian outbound travellers. Exploratory factor analysis (EFA) was used to identify key motivational factors, followed by hierarchical and k-means cluster analyses to derive and validate traveller segments.FindingsThe EFA revealed a five-factor structure comprising culture and heritage; adventure and aquatic activities; business and luxury; affordability and ease; and spatial-cultural proximity. Cluster analysis confirmed four distinct tourist segments: global nature explorers; proximity-conscious discerning explorers; indifferent travellers; and budget-conscious …
Understanding And Supporting Youth Affected By Trauma And Stress, Cara Murray, Anna Gilliam, Jared Hawkins, Christina Pay
Understanding And Supporting Youth Affected By Trauma And Stress, Cara Murray, Anna Gilliam, Jared Hawkins, Christina Pay
All Current Publications
Adults who work with youth are central to creating environments where young people feel safe, supported, and able to succeed. However, some youth have experienced stress, adversity, or trauma that can make it more difficult for them to feel safe, connected, and successful. By learning how to support youth with compassion and consistency, caring adults can help buffer the effects of adversity and promote resilience.
Re: Comment Letter For The Draft Final Butte Priority Soils Operable Unit (Bpsou) Butte Treatment Lagoons (Btl) Groundwater Treatment System Quarterly Operation And Maintenance Report – Quarter 1 2026 (Dated June 26, 2026), Emma Rott
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Improving Bench Work Competence Through Qr Code Based E-Lkpd Featuring Sop Video And K3 Safety Checklist, Firman Muhadi Saputra, Marsono Marsono, Imam Muhtarom, Mingchang Wu
Improving Bench Work Competence Through Qr Code Based E-Lkpd Featuring Sop Video And K3 Safety Checklist, Firman Muhadi Saputra, Marsono Marsono, Imam Muhtarom, Mingchang Wu
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study examines the use of a QR Code-based E-LKPD integrated with SOP videos and a K3 safety checklist in improving vocational students’ bench work competence. A pretest–posttest control group design was applied to 63 tenth-grade machining students at SMKN 1 Jenangan Ponorogo in the 2025/2026 academic year selected through purposive sampling. Data were collected using performance assessment observation sheets and written tests. The results show that both groups achieved the competent category, with the experimental class obtaining a slightly higher mean score (80.22) than the control class (77.07), However the independent t-test results indicate that the difference is not …
Heuristic Inquiry As A Research Method In Music Education, Austina F. Lee
Heuristic Inquiry As A Research Method In Music Education, Austina F. Lee
Visions of Research in Music Education
This article presents heuristic inquiry as a form of autoethnography and its potential as a methodological resource for music educators. Rather than reporting findings from a single study, the article illustrates how heuristic inquiry can serve as a structured yet flexible process of critical reflection that helps teachers navigate the cultural and political contexts of their work. Drawing on the author’s experiences as a high school choral director, the discussion highlights the six phases and seven processes of heuristic inquiry, showing how personal reflection, cultural awareness, and relational care can be interwoven into professional practice. By framing autoethnography as both …
Consequences Of Teacher Violence Among Musicians, Karla María Reynoso Vargas, Basilio Fernández-Morante
Consequences Of Teacher Violence Among Musicians, Karla María Reynoso Vargas, Basilio Fernández-Morante
Visions of Research in Music Education
This is a standalone work, but it is complementary to the study, “Teacher violence in university music education: An exploration in a Mexican context.” It presents the analysis of emerging information found in 53 stories of victims of teacher violence in university music programs. We incorporated reflections and contributions from students, professionals, and dropouts of music careers in the Mexican Republic, who voluntarily shared their stories. The first category describes the consequences of teacher violence. On one hand, there were effects interpreted as positive, including the activation of achievement orientation, overexertion, and self-demand. It is pointed out that these consequences …
Consecuencias De La Violencia Docente: Recuentos Desde El Campo De La Formación Musical Universitaria En México, Karla M. Reynoso Vargas, Basilio Fernández-Morante
Consecuencias De La Violencia Docente: Recuentos Desde El Campo De La Formación Musical Universitaria En México, Karla M. Reynoso Vargas, Basilio Fernández-Morante
Visions of Research in Music Education
Este es un trabajo independiente, pero complementario al estudio «La violencia docente en la educación musical universitaria: una exploración en el contexto mexicano». Presenta el análisis de la información que se desprende de 53 relatos de víctimas de violencia docente en programas universitarios de música. Incorporamos reflexiones y aportaciones de estudiantes, profesionales y personas que abandonaron sus carreras de música en la República Mexicana, quienes compartieron voluntariamente sus historias. La primera categoría describe las consecuencias de la violencia docente. Por un lado, se observaron efectos interpretados como positivos, entre ellos la activación de la orientación al logro, el sobreesfuerzo y …
Teacher Violence In University Music Education: An Exploration In The Mexican Context, Karla María Reynoso Vargas, Basilio Fernández-Morante
Teacher Violence In University Music Education: An Exploration In The Mexican Context, Karla María Reynoso Vargas, Basilio Fernández-Morante
Visions of Research in Music Education
This article presents the results of an exploratory phenomenological study aimed at identifying expressions of teacher violence in university music training environments in the Mexican context. We analyzed 53 accounts from students, professionals, and dropouts of music degree programs who studied at universities or conservatories across nine Mexican states and voluntarily shared their testimonies through the Mexican Association of Music Psychology (AMEPSIM). We address sociological assumptions about the dynamics of violence, the socio-educational weight of the conservatory tradition and its potential link to the limited application of contemporary pedagogical principles, as well as the normalization of teacher violence. Various forms …
Teacher Education In The Arts: A Case Study Of Constraint, Standardization, And Resistance, Terry Sefton, Danielle Sirek
Teacher Education In The Arts: A Case Study Of Constraint, Standardization, And Resistance, Terry Sefton, Danielle Sirek
Visions of Research in Music Education
In this case study, we explore one course in one Ontario initial teacher education program to examine the intersecting institutional documents and practices that regulate teaching in the arts (dance, drama, music, and visual arts). Using the feminist sociological research approach of institutional ethnography, we identify and trace institutional mechanisms that regulate teaching in the arts and how four women instructors activated or resisted those regulatory practices. Our analysis illuminated tensions between institutional policies and practices, and instructors’ efforts to maintain creativity, ambiguity, and discipline-specific experiential learning in the course. While instructors varied in their pedagogical approaches, over a seven-year …
Editorial: Colaboraciones A Través De Las Culturas/Collaborations Across Cultures, Cara Faith Bernard, Jennifer Lang
Editorial: Colaboraciones A Través De Las Culturas/Collaborations Across Cultures, Cara Faith Bernard, Jennifer Lang
Visions of Research in Music Education
No abstract provided.
Enzymatic Synthesis Of Salicylate In Yersina Pestis Proceeds Via Intramolecular Hydroxyl Group Transfer., Clarke Miller
Enzymatic Synthesis Of Salicylate In Yersina Pestis Proceeds Via Intramolecular Hydroxyl Group Transfer., Clarke Miller
Georgia Journal of Science
The salicylate synthase (YbtS) of Yersinia pestis catalyzes the initial step in the biosynthesis of yersiniabactin, an iron-scavenging siderophore and critical virulence factor. While YbtS is proposed to share a reaction mechanism with other anthranilate synthase homologs, the exact catalytic pathway has remained unresolved. In this work, stable isotope (18O) labeling and mass spectrometry are utilized to clarify the catalytic mechanism of YbtS. The results of the following set of experiments demonstrate that the salicylate hydroxyl group does not originate from solvent water, directly challenging previously proposed models. Instead, the lack of solvent-labeled oxygen incorporation and the absence …
Ummle‑1.0 — Caldwell–Copilot Universal Marine‑Medicine & Longevity Engine A Unified Open‑Hardware Biomedical Research Platform Cern‑Ohl‑P • No Patents • No Secrets • Builder‑Ready • Research‑Only, Michael Victor Caldwell Mr.
Ummle‑1.0 — Caldwell–Copilot Universal Marine‑Medicine & Longevity Engine A Unified Open‑Hardware Biomedical Research Platform Cern‑Ohl‑P • No Patents • No Secrets • Builder‑Ready • Research‑Only, Michael Victor Caldwell Mr.
Defensive Publications Series
UMMLE‑1.0 is a unified open‑hardware biomedical research platform designed to accelerate discovery, extraction, stabilization, purification, and non‑invasive delivery research for marine‑derived therapeutic compounds. Marine organisms produce powerful molecules such as anti‑cancer macrolides, antiviral peptides, neuro‑protective toxins, and non‑addictive analgesics. These compounds are fragile, shear‑sensitive, and easily degraded by heat, contamination, or mechanical stress.
UMMLE‑1.0 integrates six coordinated subsystems:
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Ultra‑Pure Water Core
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Marine Biomass Extraction Core
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Thermal Stabilization Core
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Plasma Purification Core
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Ocular Delivery Research Core
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Neural‑Glymphatic Longevity Research Core
Each subsystem is fully open‑hardware, modular, and builder‑ready.
This platform is non‑clinical, research‑only, and intended for laboratories, universities, and humanitarian research …
Competition For All? The Ftc’S Ban On Non-Competes And The More Effective Route In Promoting Competition, Aniqah Nashiat
Competition For All? The Ftc’S Ban On Non-Competes And The More Effective Route In Promoting Competition, Aniqah Nashiat
St. John's Law Review
(Excerpt)
Employment contracts have historically included non-compete agreements, which are restrictive covenants forbidding employees from working “for competitors of their former employer for a certain period of time and over a defined geographic area.” American jurisprudence has always left enforcement of these non-competes to states. In the federal government, Congress has never successfully passed legislation on the per se illegality of non-competes. Instead, President Joe Biden signed an executive order in 2021 aimed at promoting the interests of American workers because companies requiring them to sign non-competes restricted their ability to change jobs. Biden explained that strengthening antitrust laws would …
Caging Songwriters In The Compulsory Licensing Framework: A Battle Of Fairness And Equity, Maria Kaganis
Caging Songwriters In The Compulsory Licensing Framework: A Battle Of Fairness And Equity, Maria Kaganis
St. John's Law Review
(Excerpt)
Imagine it is November 2023, and you log onto Spotify to stream your favorite music. As you do, you notice you now have access to up to fifteen hours of the most popular audiobooks. You really enjoy the addition of audiobooks to Spotify and have used the new feature for months. Come March of 2024, however, you get an email stating that Spotify will be introducing a . . . music-audiobook bundle as part of your current subscription? Is that not what you already had? Shrugging it off, you move on and continue enjoying your music, audiobooks, and podcasts …
Change And Continuity: Foreign Affairs And Procedure At The Supreme Court 2024–25, Margaret E. Mcguinness
Change And Continuity: Foreign Affairs And Procedure At The Supreme Court 2024–25, Margaret E. Mcguinness
St. John's Law Review
(Excerpt)
The 100th anniversary of the founding of the Law School is a wonderful occasion to discuss how research and teaching form us as professors within the St. John’s community. I teach, research, and write about international law, international human rights, diplomacy, and the ways in which international law becomes law in the United States. I also teach civil procedure and international litigation. These two strands of my work allow me to think about the complex interplay between international law and domestic court procedure. I also have professional experience in each of these areas: First, as a career diplomat for …
How Law Changed Sex In The Twenty-First Century, Noa Ben-Asher
How Law Changed Sex In The Twenty-First Century, Noa Ben-Asher
St. John's Law Review
(Excerpt)
Thank you, wonderful students of St. John’s Law. Thank you, Professor Eva Subotnik, for your ongoing work on this event. Thank you, Dean Exum, for leading the school in these consequential times for the legal profession. And thank you, Judge Lohier, for taking the time to join us today.
Transgender issues have been in the spotlight in recent years. While many litigators and scholars think of this growing body of law and politics as “transgender rights,” I would like to persuade you in the short time that I have today that what is broadly and interestingly at stake is …
Utilization Of An Open-Access Markerless Motion Analysis Software For A Biomechanics Movement Analysis Project., Tamra L. Llewellyn, Michael J. Nolan
Utilization Of An Open-Access Markerless Motion Analysis Software For A Biomechanics Movement Analysis Project., Tamra L. Llewellyn, Michael J. Nolan
Educational Practices in Kinesiology
The movement analysis project (MAP) is a common assignment in many undergraduate biomechanics courses. The purpose of this article is to introduce kinesiology educators to an open-source, AI-enabled, markerless software for motion capture, OpenCap, which can be used in MAP and research. This tool is currently being used in an in-person, upper-level, undergraduate biomechanics course where students are required to have taken Anatomy & Physiology. There is very little time, money, or expertise needed to implement this resource. Using 2 iPads on tripods and the OpenCap app and web-based interface, movements can be quickly converted to skeleton visualization and joint …
The Gci Vortex Sentinel (Av-1): Open-Hardware Architecture For Chemical-Free Pfas And Micro-Pollutant Remediation Via Acoustic-Vortex Concentration And Plasma-Cavitation Mineralization, Michael Victor Caldwell Mr.