Digital Commons Network^™

Multi-Omics Informed Drug Response Prediction For Precision Medicine, Iyioluwa O. Adaramola, Anowarul Kabir

OneUSF Summer Undergraduate Research Symposium

Motivation: Treating cancer in patients is hard within precision oncology due to the heterogeneity in cancer cells. Developing predictive methods that estimate drug-responses in cancer cell lines can improve our understanding of treatment effectiveness. The goal of this study is to explore the fundamental and data-driven limitations of the existing advanced learning methods for drug response prediction for precision oncology.

Approach & Findings: We examine current state-of the-art methods that utilize multi-omics patient data and/or signaling pathways to predict drug response across various cell lines. Our analysis identifies that models that learn molecular and topological manifolds demonstrate richer representation of …

Design With, Not For: Augmented Reality For Understudied Populations, Safal Baral

OneUSF Summer Undergraduate Research Symposium

Augmented reality (AR) has shown promise in domains from education to healthcare. Yet, most AR research samples general adult users, overlooking populations with more specific needs. This poster presents two projects focusing on understudied groups: adults with Parkinson’s disease (PD) and children.

The first project explores AR-based cueing systems for adults with PD. Freezing of Gait (FoG) is a debilitating symptom that temporarily and involuntarily blocks movement. To study how AR can assist individuals experiencing FoG, we are conducting a qualitative study with semi-structured interviews and storyboard-based evaluations with people with PD (PwPD), alongside co-design focus groups with clinicians. We …

St. Basil's Hymn Book

William J. Marsh Papers

The Tenth Edition of the St. Basil's Hymn Book, compiled by the Basilian Fathers of Toronto and published by Benziger Brothers.

Old Favorite Songs

William J. Marsh Papers

Score of Old Favorite Songs by various composers.

Detecting Silently Blind Security Detections By Joining Rule-To-Source Dependencies Against Per-Tenant Ingestion, And Change-Impact Regression Watch For Detection Rules, Alpenshield Gmbh

Defensive Publications Series

Two related mechanisms for detection-content health in a multi-tenant security operations platform. First, a detection-blindness detector: a maintained dependency graph mapping each detection rule to the log tables its query reads is joined against per-tenant per-table ingestion volume and baselines, yielding a finding when a rule's required input table has stopped ingesting for a tenant, so the rule is silently blind even though it reports no failure. Second, a change-impact regression watch: a time-boxed watch, opened at a detection-rule change by the change pipeline or by an operator, compares post-change alert volume against the pre-change baseline and issues a verdict …

Gpu Ray Tracing And Di!Erentiable Multi-Physics Innovations, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of GPT-5.2 Thinking and Gemini 3 Reasoning, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes : EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). Description: defensive publication covering enabling inventions around GPU/RT-core ray tracing, differentiable simulation, experimental validation, interoperability (standards), operational security, sustainability, and cross-domain applications (RF/LiDAR/IR/acoustics/seismology/climate/nuclear/biophotonics/medical), …

Neuromorphic Soft Swarm Robotics, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of GPT-5.2 Thinking and Gemini 3 Reasoning, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes : EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). It discloses enabling systems and methods combining soft actuation (HASEL/EAP), event-based vision (DVS), neuromorphic computing (SNN), and swarm intelligence, covering devices/sensors, closed-loop control, …

Adaptive Control Of A Media Environment Using Synchronized Physiological Data, Rohit Jain

Defensive Publications Series

Media environments can operate without awareness of a user's physiological state, and some integration methods may be limited by factors such as high-latency cloud processing or simplistic control actions. A system is described that can establish a low-latency communication channel between one or more wearable devices, such as a smart watch or fitness tracker, and a media playback system, for example, a smart television or streaming device. With appropriate user consent, physiological data, such as heart rate variability and electrodermal activity, can be transmitted from the wearable device and processed locally on the media system. Based on this real-time analysis, …

Weibull-Aft And Random Forest Hybrid Modeling Of Diesel Generators In Burkina Faso, Zoewendbem Alain Ilboudo, Frédéric Bationo

Engineering and Technology Journal

Diesel thermal power plants are an essential link to ensure energy security in the countries of the Sahel, despite the development of renewable energies. In Burkina Faso, these plants contribute greatly to electricity production. However, their operation is influenced by a particularly restrictive environment characterized by ambient temperatures up to 49 °C, humidity variability greater than 70% and high exposure to dust. These conditions accelerate equipment degradation, reduce reliability and increase unexpected failures. This study proposes a contextualized predictive maintenance tool. Indeed, it is based on a Contextualized Global Risk Index (GPRI) combining a climate risk indicator, a probability of …

Extremophile-Inspired Biomimetics Potential Analysis, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of ChatGPT o3, GPT-5 Thinking, Gemini and Grok, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes: EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). This defensive disclosure provides enabling embodiments that translate extremophile mechanisms (thermostability, cryo-activity, anhydrobiosis, halotolerance, radiotolerance, barophily) into materials, devices, processes, control algorithms, interoperable …

The Challenges Of Romantic Relationships In Contemporary Societies, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of ChatGPT o3, GPT-5 Thinking and Grok, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes : EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). This disclosure details technical systems, methods, and architectures spanning ethical matching, socio-ecological scoring, closed-loop UX, a!ective VR, safety/consent, intergenerational models, community optimization, data …

Feasibility Study And Market Analysis – Innovations For Compact Fusion Reactors (Arc, Sparc, St-E1), Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of GPT-5.2 Thinking and Gemini 3 Reasoning, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes : EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). It covers four compact-fusion bottlenecks (vapor-shielding thermal protection, active control of HTS REBCO magnets, irradiation-driven self-healing structural materials, and chiral tritium-breeding blankets) and …

2026 August 18 - Faculty Senate Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

Experiencing God Firsthand, Joseph Khabbaz

The Main Thing Devotional

Why settle for a secondhand faith when you can have a firsthand experience with God?

Learning Challenges And Their Correlation Among Nursing Students Using Artificial Intelligence Bots, Sofia Magdalena Norbe Robles, Francine Isabel M. Adarne, Astrid Jaide Arellano, Charlene Azucenav, Ianne Jasmine A. Bayan, Luis Manuel M. Caudal, Angelica S. De Guzman, Jan Philip Dela Cruz, Gweneth E. Gabon, Adrian Paolo P. Mabahague, Rebeka L. Ricabierta, Andru Nicolas P. Rosal, Jodi Darla S. Taroc, Sheena Margaret B. Valera

International Nursing Research Congress (INRC)

The rise of Artificial Intelligence (AI) has profoundly transformed the digital age, bringing notable implications for nursing education. AI, defined as the simulation of human intelligence in machines (Duggal, 2023), has revolutionized nursing, where students face various challenges related to Knowledge, Skills, and Attitudes (KSA) when using AI bots for academic purposes. This study examines the learning challenges encountered by nursing students in the domains of knowledge, skills, and attitudes (KSA) when using AI bots for academic purposes, particularly in relation to ethical considerations.

A descriptive-correlational research design was employed, using structured questionnaires to analyze the relationship between demographic profiles, …

Immigration Stress And Inequities Driving Diabetes Distress In Hispanic Adults: A Scoping Review, Rachell Nguyen

International Nursing Research Congress (INRC)

Background: Hispanic adults in the United States experience disproportionately high rates of type 2 diabetes mellitus (T2DM) and co-occurring mental health conditions. These disparities are intensified by immigration-related stress, acculturation challenges, and minority stress, all of which contribute to heightened diabetes distress and reduced self-management capacity.

Purpose: This scoping review examined how immigration stressors, acculturation processes, and minority stress influence diabetes distress and mental health outcomes among Hispanic adults with T2DM.

Methods: Using Arksey and O’Malley’s six-step scoping review framework and PRISMA-ScR guidelines, a comprehensive search of PubMed, CINAHL Complete, MEDLINE (OVID), and ScienceDirect identified studies published between 2015 and …

Risk Stratification And Screening For Sleep Apnea In Cardiology Outpatient Setting, Ma Vanessa Simoy Mabazza, Tanya Tanzillo, Paul H. Nguyen, Rubina D. Nguyen

International Nursing Research Congress (INRC)

Background: Obstructive sleep apnea (OSA) is the most prevalent sleep disorder and is strongly associated with cardiovascular disease (CVD), but remains widely underdiagnosed due to inconsistent and non-standardized screening practices in outpatient settings.

Local Problem: Patients with CVD were reported to be diagnosed with OSA following sleep studies at an outpatient cardiology clinic. The need for a consistent, evidence-based approach to risk-stratification and screening was recognized.

Aim: The aim of this project was to increase the sleep apnea risk stratification rate among new adult cardiology patients from 53% to at least 85% over a 16-week implementation period by incorporating the …

Bridging Theory And Innovation: Cultivating Nursing Scholars Through Research, Ai And Mentorship, Charlene Whitaker-Brown, Judy Cornelius

International Nursing Research Congress (INRC)

As a newly R1 Carnegie Classification institution, in the Southeastern part of the United States, there is renewed emphasis on expanding research opportunities for undergraduate and graduate students. In response, the Research Explorer Program commencing in Winter 2025 is being launched as a pilot initiative to enhance student research engagement within the School of Nursing.

This program introduces a cohort of 10 undergraduate nursing students to the fundamentals of nursing research through mentorship with graduate nursing students. Grounded in the belief that early exposure to research strengthens clinical reasoning, evidence-based practice, and leadership, the initiative will provide undergraduates with hands-on …

Fmea-Based Risk Assessment And Improvements For Vascular Access Education In Hemodialysis, Nai-Hua Hsiao

International Nursing Research Congress (INRC)

This study evaluates and improves the patient education and care process before and after arteriovenous fistula surgery in hemodialysis patients. Inadequate implementation of this process may lead to multiple clinical risks. Currently, Southern X Hospital lacks a standardized patient education protocol, resulting in duplicated, omitted, or inconsistent content. These deficiencies negatively affect patients' comprehension and adherence, potentially leading to resource waste and reduced dialysis quality. To address these issues, this study applies Failure Mode and Effects Analysis (FMEA) to systematically identify potential failure modes within the education and care continuum. The CRITIC (Criteria Importance Through Intercriteria Correlation) method is used …

Multi-Interactive Teaching For Clinical Nursing Preceptors: Impact On Learning Styles And Competence, Shui-Tao Hu, Shu-Ling Yeh, Yi-Ling Chang

International Nursing Research Congress (INRC)

Background: Newly recruited nurses face high turnover and adaptation challenges, requiring clinical preceptors to possess diversified teaching competencies. Multi-interactive teaching, integrating simulation, discussion, and immediate feedback, can enhance teaching reflection and professional development.

Purpose: To examine the effects of multi-interactive teaching on clinical preceptors’ learning styles and teaching competence.

Design: Quasi-experimental, one-group pretest-posttest design.

Methods: Six multi-interactive workshops were conducted for experienced clinical preceptors, covering preceptor characteristics, learner learning styles, teaching competence, and strategies for coaching difficult learners. Workshops included seminars and real-time interactive communities. Participants were registered nurses (clinical ladder 3 or above, or ladder 2 with >5 years’ …

Rewilding Health: A Global Nursing Framework For Nature-Based Interventions And Planetary Well-Being, Amber Lea Vermeesch, Mary Rockwood Lane, Erica Timko Olson

International Nursing Research Congress (INRC)

Purpose: Rewilding—defined as restoring natural ecosystems and reconnecting humans to nature—offers a scalable, evidence-informed strategy to advance global health goals identified by the World Health Organization and United Nations Sustainable Development Goal (SDG) 3. This project examines how nurses can operationalize rewilding and nature-based interventions (NBIs) as ethical, clinical, and policy actions supporting universal health coverage, mental health promotion, non-communicable disease prevention, and global well-being.

Background: Growing evidence demonstrates that exposure to nature reduces stress, improves immune function, decreases depression and anxiety, enhances cancer survivorship outcomes, and promotes social connectedness. Aligning with Watson’s Unitary Caring Science and Chinn’s Emancipatory Nursing, …

Trends And Characteristics Of Behavioral Trials On Hpv Vaccination: A Systematic Review (2006-2025), Jutamas Suwannawat, Megan Whaley, Tsui-Sui Annie Kao, Angela Chia-Chen Chen

International Nursing Research Congress (INRC)

Background: Although human papillomavirus (HPV) vaccination has effectively prevented HPV-related cancers and infections since 2006 (Rosenblum et al., 2022; Semprini et al., 2025), uptake remains suboptimal (Franco et al., 2019; Guo et al., 2025; Han et al., 2025). Behavioral clinical trials have increasingly sought to enhance HPV uptake, yet few have examined overall trends. This study examined trends and characteristics of behavioral HPV vaccine trials between 2006 and 2025.

Methods: We searched ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform, and the International Standard Randomized Controlled Trial Number for behavioral HPV vaccination trials registered between 2006 and 2025. Inclusion criteria …

God's Will Or Man's? The Power Of Religious Rhetoric In Shaping Wartime Domestic Policy Preferences, Claire E. Brimhall

Undergraduate Honors Theses

How do individuals represent their religious beliefs in the political sphere? Is this impacted by levels of conflict in a given society? In times of war, people of faith often rally behind leaders and policies that diverge from the values upheld by their religious institutions. In fact, in many such cases, religious affiliation and church attendance are among the strongest predictors of support for these political actors.

This thesis examines two such cases where religious voters support policies that contradict the moral teachings of their faith, advancing a theory that a state’s appeals to religion can fundamentally reshape how believers …

Molecular Pathogenesis And Genomic Profiling Of Fusobacterium Nucleatum: A Review Of Virulence Determinants & Antimicrobial Resistance Mechanisms In Dental And Systemic Infections, Mawahb Hatem Mones, Thariat Abdualrahman Al-Joubori, Ibrahim Faisal Ibrahim

Muthanna Medical Journal

Fusobacterium nucleatum is one of the key bacteria in the oral microbiota, which plays a key role in the structural integrity of dental plaque, an anaerobic bacterium. Emerging clinical evidence has increasingly linked this opportunistic pathogen to severe systemic pathologies, notably colorectal cancer and adverse pregnancy outcomes. This review synthesizes current genomic and molecular insights to elucidate the complex mechanisms driving fusobacterial virulence and antimicrobial resistance (AMR). We critically discuss the roles of key adhesins, such as FadA and Fap2, in modulating host cell signaling and facilitating immune evasion. Furthermore, we determine the genomic architecture involved in the transfer …

Are 2d:4d Finger-Length Ratios Related To Bdsm Power Play Roles? An Exploratory Study, Phoenix R. Crane

Psychology and Neuroscience Faculty Publications

This study explored the relationships between 2D:4D ratio, a biological marker influenced by prenatal androgen exposure, and personality traits among members of the BDSM community. The 2D:4D ratio, calculated by dividing the length of the second (index) finger by the length of the fourth (ring) finger, is a non-invasive measure of prenatal exposure to androgens, with a smaller 2D:4D ratio associated with higher levels of testosterone exposure. Previous, albeit conflicting, research suggests that higher levels of testosterone are associated with dominance, aggression, risk-taking, and sensation-seeking. The present study draws on these findings to propose an androgenization of power play roles. …

Selective Loss Of Primary Cilia And Neurotrophic Signaling In G51d Α-Synuclein Mice Highlights A Common Pathway To Parkinson’S Disease, Yu-En Lin, Ebsy Jaimon, Youngdoo Kim, Annabeth Loftman, Aaran Vijayakumaran, Benjamin D W Belfort, Claire Y Chiang, Benjamin R Arenkiel, Huda Y Zoghbi, Suzanne R Pfeffer

Duncan NRI Faculty and Staff Publications

Parkinson's disease is characterized by dopaminergic neuron loss and accumulation of α-synuclein aggregates in the brain. G51D α-synuclein knock-in mice provide a genetically and clinically relevant model of disease, exhibiting early olfactory deficits, age-dependent motor impairment, and progressive phospho-α-synuclein accumulation. In multiple Parkinson's disease models, striatal cholinergic and parvalbumin interneurons, as well as astrocytes, lose primary cilia and the neurotrophic signaling needed to sustain dopaminergic neurons. We show here that G51D α-synuclein mice share these phenotypes. Phospho-Ser129 α-synuclein accumulation correlates with cilia loss in cholinergic interneurons but not in spiny projection neurons that accumulate higher phospho-α-synuclein levels. In the piriform …

Improved Foraminal Expansion And Pain Scores Following Placement Of Novel Expandable Interlaminar Stabilization Device For Lumbar Spinal Stenosis, Robert P. Norton, Ian Koch, Kendra Primavera, Roy Y. Miloh, Alex R. Vaccaro, Mitchell K. Ng

Department of Orthopaedic Surgery Faculty Papers

STUDY DESIGN: Retrospective cohort study.

OBJECTIVE: To evaluate radiographic durability and clinical outcomes following placement of a novel expandable interlaminar stabilization device for single-level lumbar spinal stenosis. Specifically, we aimed to: 1) quantify immediate postoperative posterior column distraction; 2) determine whether foraminal expansion is improved postoperatively without radiographic subsidence; and (3) assess potential improvements in patient-reported pain/clinical outcomes.

METHODS: A retrospective review was performed of adult patients undergoing single-level decompression supplemented by an interlaminar device for symptomatic lumbar spinal stenosis by a single surgeon from 2024 to 2025. Radiographic parameters included anterior, middle, and posterior disc height, foraminal height, and …

August 18, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Software Tools And Simulation Exercises For Radiation Oncology Cyber-Attack Resiliency, Yevgeniy Vinogradskiy, James Lamb

Department of Radiation Oncology Faculty Papers

This review summarizes the rationale for radiation oncology cyberattack simulation exercises, recent results from multi-institutional resiliency drills, and the landscape of software tools developed to help clinics resume radiotherapy treatments rapidly and safely during a cyberattack or other major clinical software outage. Simulation exercises using record-and-verify (R&V) downtime and File Mode treatment delivery have identified failure modes not apparent in theoretical planning alone, including risks related to treatment documentation, repeated fractions, patient setup, and missed safety checks. Available software tools emphasize insulated backup of DICOM-format planning data and clinical notes, treatment-state dashboards, File Mode treatments, redundant R&V installations, and human-readable …

Parents’ Perceptions Of Their Children With Disabilities’ Mental Health During The Rapid Transition To Online Learning At The Time Of The Covid-19 Pandemic, Arnell Rorie Footman

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic prompted an abrupt shift to online learning, raising significant concerns about the mental health of children with disabilities. Existing research highlights increased rates of anxiety, depression, and social isolation during due to the disruptions in structured routines and in-person support systems. This generic qualitative study, guided by Bronfenbrenner’s EST was conducted to explore parents’ perceptions of the mental health challenges experienced by their students with disabilities during the rapid transition to online learning at the time of COVID-19 pandemic. Data was obtained through semi-structured interviews in which parents voiced their perceptions and experiences concerning their children’s mental …