Digital Commons Network^™

Following The Thread: Maria Lai’S 1981 Legarsi Alla Montagna, Claire Borre

Theses and Dissertations

This thesis examines Maria Lai’s (1919-2013) Legarsi alla montagna (1981), a three-day, relational project in which seventeen miles of ribbon were wound through the Sardinian town of Ulassai. In its conception, execution, and legacy, Lai’s project represented a significant challenge to traditional monumentality.

Airbnb And The End Of The Local, Nadia Beyersdorf

Theses and Dissertations

This thesis examines how second-home ownership and self-catered tourism reshape community life in Tenby, Wales. While gentrification research often focuses on permanent displacement, less attention has been given to the movement of temporary residents that erodes local culture, social ties, and transforms everyday relationships in coastal towns.

Retroactive Eligibility Waivers: Innovative Or Ineffective?, Mohamed Kacem Benyamine

Theses and Dissertations

Medicaid’s retroactive eligibility provision covers medical expenses for beneficiaries up to 90 days before the application date. Retroactive eligibility insulates uninsured, low-income households from expensive healthcare emergencies. New Hampshire, Arkansas, and Iowa recently obtained waivers to end retroactive coverage. Using a difference-in-differences design and data from the Behavioral Risk Factor Surveillance System, I evaluate whether changes in retroactive coverage affect enrollment rates and self-reported health. Removing retroactive eligibility has no statistically significant effects on insurance enrollment or self-reported health. However, it does increase rates of access to a doctor by 1.0% overall and by 1.6% for women. Removing retroactive eligibility …

Fugitive Formalisms: Strategies Of Dissemblance And Dissent In The Work Of Queer-Identifying Artists, 1970–Present, Rowan Diaz-Toth

Theses and Dissertations

Utilizing case studies of works by Hélio Oiticica, Scott Burton, and Felix Gonzalez-Torres as points of departure, this thesis puts forth a speculative historical framework for reconsidering queer art practices up through the present day in opposition to regimes of visibility and transparency, exploring the subversive, fugitive potential of non-representational formalisms.

The Role Of Exotic Plants In The Diet Of Black-And-White Colobus Monkeys (Colobus Guereza) In Kibale National Park, Uganda, Michelle Gaykov

Theses and Dissertations

Exotic plants have both positive and negative impacts on their environment. They may act as additional food sources for the local fauna or as competition for local flora or leading to changes within a landscape or ecosystem. To considere the role of exotics in primate diet, this study focused on the dietary role of exotic plant species in the diet of a leaf-eating foregut fermenting monkey, the black-and-white colobus monkeys (Colobus guereza) in Kibale National Park, Uganda. Int this study, I followed individuals in two groups of black-and-white colobus monkeys for 21 days recording their food intake (0700-1900). I also …

Qualitative Exploration Of Hallucinations Among Adolescents With Suicide Ideation And/Or Attempts, Rebecca E. Lewis

Theses and Dissertations

A qualitative study exploring and characterizing how psychotic experiences (PEs), specifically hallucinations, may affect suicidal behaviors in adolescents. Thematic analysis revealed eight key themes within the connection, capturing unique perspectives and nuanced meanings. Exploring this intersection may increase the understanding of adolescent PEs and help inform more targeted interventions.

One Stone's Journey, Satoko Saito

Theses and Dissertations

One Stone’s Journey is a participatory, experiential thirty-minute documentary about uranium. By using an embroidered world map and appealing to participants’ senses—especially touch—the project explores the possibility of telling the story of radiation, which is invisible, intangible, and silent. Uranium is a radioactive material used by the United States in the development and production of the atomic bombs during the Manhattan Project. This year, 2025, marks the 80th anniversary of the atomic bombings of Hiroshima and Nagasaki. The Fukushima Daiichi nuclear power plant accident in 2011 was on a scale comparable to the Chernobyl disaster of 1986, and the threat …

The Effect Of Medical Aid In Dying On Health Outcomes And Risky Behavior Of The Elderly, Jacky Wu

Theses and Dissertations

This study examines the effects of Medical Aid in Dying (MAiD) legalization on health outcomes and behavior among elderly U.S. adults using BRFSS data from 2005-2022. Using staggered difference-in-differences, this paper finds that MAiD increases exercise, lowers BMI, and reduces blood pressure medication use.

Career Plans Among Graduating Us Emergency Medicine Residents, Dave W. Lu, Bo Gu, D. Mark Courtney, Bryan G. Kane, Michelle D. Lall, Michael Gottlieb, Yvette Calderon, Christopher Bennett

Department of Emergency Medicine Faculty Papers

IMPORTANCE: The emergency medicine (EM) workforce is undergoing complex change, including a potential projected physician surplus, the volatile and evolving interests of medical students, and the continued high rates of burnout. Understanding the career intentions of graduating residents is critical to inform workforce planning.

OBJECTIVE: To examine the career plans, anticipated career durations, and key factors associated with the career decisions of graduating US EM residents.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional survey study, which sampled graduating residents from all Accreditation Council for Graduate Medical Education-accredited categorical EM programs, was conducted after the 2023 American Board of Emergency Medicine In-Training …

Review Of Human Anatomy And Physiology Preparatory Course, Alex Zuo

Open Educational Resources - Reviews

No abstract provided.

Precision Acoustofluidics For High-Throughput Mechanobiology In Suspension Cells, Kaichun Yang, Ruoyu Zhong, Ke Li, John Mai, Pengzhan Liu, Ye He, Joseph Rich, Ying Chen, Janna Wang, Zhiteng Ma, Zhiteng Ma, Xianchen Xu, Qian Wu, Tony Jun Huang

Faculty Publications

Mechanomodulation, the process of altering cellular behavior through applied mechanical forces, plays a critical role in physiological processes and has substantial implications for cancer therapy, immunology, and drug development. However, precise and efficient stimulation of nonadherent cells remains a major challenge, limiting the investigation of mechanotransduction pathways and the development of targeted therapeutics. Here, we developed an acoustofluidic platform named Suspension-cell Targeted Response to Excitation via Acoustofluidic Mechanomodulation (STREAM) to enable precise, high-throughput stimulation of suspension cells. STREAM accomplishes this using 101.14-megahertz high-frequency surface acoustic waves to deliver controlled mechanical stimulation at a throughput of 500,000 cells per minute. STREAM …

Light Is Not Always Right: Peri-Iridial Lightness Reduces Attractiveness Via Perceived Sex-Typicality Across Human Populations, Vojtěch Fiala, Juan Olvido Perea-García, Petr Tureček, Sławomir Wacewicz, Juan David Leongómez, Šimon Pokorný, Ondřej Pavlovič, S. Adil Saribay, Farid Pazhoohi, Robert Mbe Akoko, Karel Kleisner

School of Psychology

Abstract: Evolutionary psychology views the human eye as special. In particular, it claims that the light peri-iridial tissues surrounding a relatively darker iris form a combination that sets us apart from other primates. From this perspective, much less attention has been paid to how eye colouration varies between humans, although evidence indicates that variations in peri-iridial and iridial colouration influence both perceived facial attractiveness and sex-typicality. To determine what aspects of eye colouration influence the perception of faces, we have measured the colour of peri-iridial eye tissues (‘the white of the eye’) and the iris in nine samples from seven …

Career Plans Among Graduating Us Emergency Medicine Residents, Dave W. Lu, Bo Gu, D. Mark Courtney, Bryan G. Kane, Michelle D. Lall, Michael Gottlieb, Yvette Calderon, Christopher Bennett

Department of Emergency Medicine Faculty Papers

IMPORTANCE: The emergency medicine (EM) workforce is undergoing complex change, including a potential projected physician surplus, the volatile and evolving interests of medical students, and the continued high rates of burnout. Understanding the career intentions of graduating residents is critical to inform workforce planning.

OBJECTIVE: To examine the career plans, anticipated career durations, and key factors associated with the career decisions of graduating US EM residents.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional survey study, which sampled graduating residents from all Accreditation Council for Graduate Medical Education-accredited categorical EM programs, was conducted after the 2023 American Board of Emergency Medicine In-Training …

Cognitive And Economic Development, John Luke Gallup

Economics Faculty Publications and Presentations

A burgeoning literature has found that early childhood health conditions of individuals have large causal effects on their cognitive development, education and earnings. How much does early cognitive development contribute to the national economy? Although researchers have long studied the role of worker health for economic growth, they have not assessed the role of early cognitive development.

Cognitive ability is the foundation of human capital, affecting both educational attainment and economic growth. The risk factors for poor cognitive development are very high in many countries. Each risk factor also causes child mortality, making child survival a viable proxy for good …

Continuous Learning And Customer Value Creation In The Healthcare: Mediating Effects Of Innovations Adoption Value Recognition, Binto M. Binto, Omari Khalifa Mbura

Business Management Review

This research investigates the influence of continuous learning on the effectiveness of customer value creation in the Tanzania’s healthcare system, with a specific focus on the mediating effects of innovation adoption value recognition. Using a cross-sectional design, data were collected from 360 healthcare professionals across three zonal referral hospitals in Tanzania. Data analysis employed a structural equation modelling using SMART-Partial Least Squares software version 4.0. The findings indicate that continuous learning enhances healthcare customer value creation both directly and indirectly. Also, innovation adoption value recognition serves as a mediating variable of the direct causal relationship, offering partial mediation effects between …

Dual Challenges, Shared Wins: Unlocking Climate Financing For Nutrition, Chiara Dell’Aira, Natalia Rovelo-Velazquez, Sarah Lahaye, Xiu Xin Catherine Lok, Stella Nordhagen, Stephen Dorey, Mireya Vilar-Compte

Department of Public Health Scholarship and Creative Works

Background

The intertwined challenges of climate change and malnutrition amplify each other, with climate change exacerbating malnutrition, particularly in vulnerable populations; and food systems significantly contributing to emissions and environmental degradation. Addressing these issues together offers opportunities for shared gains, yet funding streams for these sectors remain siloed and misaligned.

Objective

This study developed a scoring methodology to assess the compatibility of climate funds with financing nutrition-related actions where synergies align with climate funds’ primary goals, referred to as the “scope for nutrition integration”.

Methods

Using the Climate Funds Update database, 18 active climate funds were systematically reviewed …

Cost-Effectiveness Of Home-Based Self-Sampling Vs Clinician Sampling For Anal Precancer Screening, Haluk Damgacioglu, Timothy L Mcauliffe, Timothy J Ridolfi, Elizabeth Chiao, Maria E Fernandez, Vanessa Schick, Jennifer S Smith, Bridgett Brzezinski, Jenna Nitkowski, Ashish A Deshmukh, Alan G Nyitray

Faculty, Staff and Student Publications

Importance: Anal cancer screening is recommended for high-risk populations, particularly sexual and gender minority (SGM) individuals. However, the cost-effectiveness of home-based self-sampling in increasing anal cancer screening uptake has not yet been evaluated in the US.

Objective: To evaluate the cost-effectiveness of home-based anal self-sampling compared with clinic-based screening among SGM individuals.

Design, setting, and participants: This economic evaluation used data from a 2-group randomized clinical trial conducted in Milwaukee, Wisconsin, from January 2020 to August 2022, enrolling SGM individuals aged 25 years or older. Participants were randomized to home-based self-sampling or clinic-based screening. Costs for home-based screening were obtained …

Type Iv Secretion Systems: Reconciling Diversity Through A Unified Nomenclature, Peter J Christie, Gabriel Waksman, Ronnie Per-Arne Berntsson, Nicolas Soler, Nathalie Leblond-Bourget, Badreddine Douzi

Faculty, Staff and Student Publications

Type IV secretion systems (T4SS) are versatile nanomachines responsible for the transfer of DNA and proteins across cell envelopes. From their ancestral role in conjugation, these systems have diversified into a superfamily with functions ranging from horizontal gene transfer to the delivery of toxins to eukaryotic and prokaryotic hosts. Recent structural and functional studies have uncovered unexpected architectural variations not only among Gram-negative systems but also between Gram-negative and Gram-positive systems. Despite this diversity, a conserved set of core proteins is maintained across the superfamily. To facilitate cross-system comparisons, we propose in this review a unified nomenclature for conserved T4SS …

Laboratory Evaluation Of Armie, A Portable Sps30-Based Low-Cost Sensor Node For Pm 2.5 Monitoring., Asbjørn Kloppenborg, Louise B Frederickson, Rasmus Ø Nielsen, Clive E Sabel, Tue Skallgaard, Jakob Löndahl, Jose G C Laurent, Torben Sigsgaard

School of Geography, Earth and Environmental Sciences

BACKGROUND: Low-cost particulate matter sensors have enabled new opportunities for exposure monitoring but require evaluation before application in epidemiological studies. This study assessed the performance of the SPS30 sensor integrated into the ARMIE portable monitoring sensor-node under controlled laboratory conditions.

METHODS: Sensors were co-located with two comparison instruments-the optical DustTrak photometer and the combined Scanning Mobility Particle Sizer (SMPS) and Aerodynamic Particle Sizer (APS)-across multiple aerosol sources, including candle burning, cooking, cigarette smoke, and clean air, under both regular and high-humidity conditions. Calibration performance was evaluated using leave-one-sensor-out and leave-one-source-out approaches.

RESULTS: The ARMIE node demonstrated strong agreement with the …

A Recurrent Neural Network For Forecasting Dead Fuel Moisture Content With Inputs From Numerical Weather Models, Jonathon Hirschi, Jan Mandel, Kyle Hilburn, Angel Farguell

Faculty Research, Scholarly, and Creative Activity

This paper proposes a recurrent neural network (RNN) model of dead 10 h fuel moisture content (FMC) for real-time forecasting. Weather inputs to the RNN are forecasts from the High-Resolution Rapid Refresh (HRRR), a numerical weather model. Geographic predictors include longitude, latitude, and elevation. Forecast accuracy is estimated in a study that utilizes a spatiotemporal cross-validation scheme. The RNN is trained on HRRR forecasts and observed FMC from weather station sensors within the Rocky Mountain region in 2023, then used to forecast FMC at new locations for all of 2024. The model is evaluated using a 48 h forecast window. …

Etoposide-Associated Severe Rhabdomyolysis In A Patient With Diffuse Large B-Cell Lymphoma: A Case Report And Review Of The Literature, Ibrahim Al Nabhani, Ruquiya Al Dhuhli, Farah Al Kindy, Mahmood Al Abri, Khalil Al Farsi, Almundher Al Oraimi

Sultan Qaboos University Medical Journal

Rhabdomyolysis is a clinical syndrome characterised by skeletal muscle necrosis with subsequent release of intracellular constituents into the circulation. Although multifactorial in aetiology, chemotherapeutic agents, including etoposide, are rarely implicated. We report a 62-year-old male who presented to a tertiary care hospital in Muscat, Oman, in 2023 with severe rhabdomyolysis and advanced-stage diffuse large B-cell lymphoma following the first cycle of R-CEOP chemotherapy. Extensive evaluation excluded infectious, inflammatory and structural neuromuscular aetiologies. Work-up for metabolic myopathy suggested, but did not confirm, multiple acyl-CoA dehydrogenase deficiency. The patient’s clinical course was complicated by acute kidney injury necessitating dialysis, followed by gradual …

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-06 Site Evaluation Summary Report (Dated December 10, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-22 Site Evaluation Summary Report (Dated December 10, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-12 Site Evaluation Summary Report (Dated December 9, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Peroxisomal Integrity In Demyelination-Associated Microglia Enables Cellular Debris Clearance And Myelin Renewal In Mice, Joseph A Barnes-Vélez, Xiaohong Zhang, Yaren L Peña Señeriz, Kiersten A Scott, Yinglu Guan, Jian Hu

Faculty, Staff and Student Publications

Demyelination associated microglia (DMAM) orchestrate the regenerative response to demyelination by clearing myelin debris and promoting oligodendrocyte maturation. Peroxisomal metabolism has emerged as a candidate regulator of DMAMs, though the cell-intrinsic contribution in microglia remains undefined. Here we elucidate the role of peroxisome integrity in DMAMs, using cuprizone-mediated demyelination coupled with conditional KO of peroxisome biogenesis factor 5 (PEX5) in microglia. Absent demyelination, PEX5 conditional KO (PEX5cKO) had minimal impact on homeostatic microglia. However, during cuprizone-induced demyelination, the emergence of DMAMs unmasked a critical requirement for peroxisome integrity. At peak demyelination, PEX5cKO DMAMs exhibited increased lipid droplet burden and reduced …

Public Support For Alcohol-Control Policies And Political Ideology In The Us, Joël Fokom Domgue, Robert Yu, Ernest Hawk, Sanjay Shete

Faculty, Staff and Student Publications

This cross-sectional study examines the role of US adults’ political affiliation, perception about alcohol use and cancer, and sociodemographic and behavioral factors in banning outdoor alcohol advertising and adding cancer warnings on alcohol containers.

Cholesterol Efflux Protein, Abca1, Supports Anticancer Functions Of Myeloid Immune Cells, Shruti V Bendre, Yu Wang, Basel Hajyousif, Rajendra K C, Shounak G Bhogale, Dhanya Pradeep, Natalia Krawczynska, Claire P Schane, Erin Weisser, Avni Singh, Simon Han, Hannah Kim, Lara Kockaya, Anasuya Das Gupta, Adam T Nelczyk, Hashni Epa Vidana Gamage, Yifan Fei, Desirée Rodríguez-Casiano, Xingyu Guo, Haoyun Li, Ryan J Deaton, Fei Mo, Maria Sverdlov, Peter H Gann, Saurabh Sinha, Sahil Sahni, Kun Wang, Kevin Van Bortle, Emad Tajkorshid, Wendy A Woodward, Wonhwa Cho, Erik R Nelson

Faculty, Staff and Student Publications

Breast and other solid tumors respond poorly to immune therapy. Myeloid cells (MCs) such as macrophages contribute to resistance. Established clinical evidence links cholesterol to cancer outcomes, with MC function being regulated by cholesterol metabolism. We screened MC-expressed regulators of cholesterol homeostasis linked to survival and identified the cholesterol efflux protein ABCA1. ABCA1 activity increases anticancer functions of macrophages: enhancing tumor infiltration, decreasing angiogenic potential, reducing efferocytosis, and improving support of CD8+ T cell activity. Mechanistically, different AKT isoforms are involved, through both PI3K-dependent and PI3K-independent mechanisms. Highlighting the clinical relevance of our findings are correlations between ABCA1 in macrophages …

Nf2 Loss Malignantly Transforms Human Pancreatic Acinar Cells And Enhances Cell Fitness Under Environmental Stress, Yi Xu, Michael H Nipper, Angel A Dominguez, Chenhui He, Francis E Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang

Faculty, Staff and Student Publications

Pancreatic ductal adenocarcinoma (PDAC) occurs as a complex, multifaceted event driven by the interplay of tumor-permissive genetic mutations, the nature of the cellular origin, and microenvironmental stress. In this study, using primary human pancreatic acinar 3D organoids, we performed a CRISPR-KO screen targeting 199 potential tumor suppressors curated from clinical PDAC samples. Our data revealed significant enrichment of a list of candidate genes, with neurofibromatosis type 2 associated gene (NF2) emerging as the top target. Functional validation confirmed that loss of NF2 promoted the transition of PDAC to an invasive state, potentially through extracellular matrix modulation. NF2 inactivation …

Racial, Ethnic, And Socioeconomic Survival Disparities In Early-Onset Metastatic Colorectal Cancer, Jennifer S Wang, Benny Johnson, Caitlin C Murphy

Faculty, Staff and Student Publications

Importance: Rates of metastatic colorectal cancer (mCRC) are rising among young adults. Disparities by race and ethnicity and neighborhood-level socioeconomic status (SES) among this population are understudied.

Objective: To examine the association of race and ethnicity and neighborhood-level SES with mortality among a community-based sample of young adults with mCRC.

Design, setting, and participants: This cohort study used a large electronic health record-derived database of young adults with cancer treated at 280 community-based US clinics between 2013 and 2021. Eligible patients were young adults aged 18 to 49 years diagnosed with de novo or recurrent mCRC. Patients were followed up …

Medicaid Expansion And Breast Cancer Care And Outcomes-What Lies Ahead?, Meghan H. Maceyko, Oluwadamilola M. Fayanju

Department of Surgery Faculty Papers

No abstract provided.