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Articles 24871 - 24900 of 27127
Full-Text Articles in Entire DC Network
Dystop: Dynamic Staleness Control And Topology Construction For Asynchronous Decentralized Federated Learning, Yizhou Shi, Qianpiao Ma, Yan Xu, Junlong Zhou, Ming Hu, Yunming Liao
Dystop: Dynamic Staleness Control And Topology Construction For Asynchronous Decentralized Federated Learning, Yizhou Shi, Qianpiao Ma, Yan Xu, Junlong Zhou, Ming Hu, Yunming Liao
Research Collection School Of Computing and Information Systems
Federated Learning (FL) has emerged as a potential distributed learning paradigm that enables model training on edge devices (i.e., workers) while preserving data privacy. However, its reliance on a centralized server leads to limited scalability. Decentralized federated learning (DFL) eliminates the dependency on a centralized server by enabling peer-to-peer model exchange. Existing DFL mechanisms mainly employ synchronous communication, which may result in training inefficiencies under heterogeneous and dynamic edge environments. Although a few recent asynchronous DFL (ADFL) mechanisms have been proposed to address these issues, they typically yield stale model aggregation and frequent model transmission, leading to degraded training performance …
Llamoco: Instruction Tuning Of Large Language Models For Optimization Code Generation, Zeyuan Ma, Yue-Jiao Gong, Hongshu Guo, Jiacheng Chen, Yining Ma, Zhiguang Cao
Llamoco: Instruction Tuning Of Large Language Models For Optimization Code Generation, Zeyuan Ma, Yue-Jiao Gong, Hongshu Guo, Jiacheng Chen, Yining Ma, Zhiguang Cao
Research Collection School Of Computing and Information Systems
Recently, combining the strength of large language models (LLMs) and Evolutionary Computation (EC) has shown promising results for addressing optimization problems. It typically involves either iterative next-step solution seeking or directly prompting LLMs to generate critical optimization codes. However, these methods often suffer from low computational efficiency, high sensitivity to prompt design, and a lack of domain-specific knowledge. We introduce LLaMoCo, the first instruction-tuning framework designed to adapt LLMs for solving optimization problems in a code-to-code manner. LLaMoCo features a comprehensive instruction set that includes code-style problem descriptions as input prompts and robust optimization codes from expert EC optimizers as …
Understanding Wage Theft: Beyond The Numbers Through Community Practice, Lived Experience, And Research, André Simões Da Silva, Lenita Reason, Cristina Araujo Brinkerhoff
Understanding Wage Theft: Beyond The Numbers Through Community Practice, Lived Experience, And Research, André Simões Da Silva, Lenita Reason, Cristina Araujo Brinkerhoff
Gastón Institute Publications
Wage theft is a widespread form of labor exploitation that disproportionately affects immigrant and other vulnerable workers. This report examines the scope and impact of wage theft in Massachusetts by analyzing case data from the Brazilian Worker Center (BWC) alongside wage and labor enforcement data from the Massachusetts Attorney General’s Office (AGO). The analysis demonstrates how wage theft affects immigrant workers across industries, with particularly high numbers of cases in construction, cleaning, and hospitality. The data also reveal significant gaps in the reporting and enforcement of wage violations, particularly among domestic workers, whose cases are likely substantially underrepresented in available …
Social Support, Trauma And Neurophysiological Stress, Devon S. Glicken
Social Support, Trauma And Neurophysiological Stress, Devon S. Glicken
UNF Graduate Theses and Dissertations
Traumatic life experiences and the prolonged effects of stress can negatively impact an individual’s mental and physical health. Hyperreactivity to acute stressors can often be seen in individuals with anxiety, depression, and suicidal ideations, conditions commonly observed with endocrine dysfunction. How do traumatic experiences, particularly experiences related to military affiliation, influence stress responses and feelings of burdensomeness and thwarted belongingness? This study predicted (1) that military-affiliated individuals (and those with PTSD symptomology and high perceived life stress) will have heightened neurophysiological responses to minor levels of acute stress compared to individuals without military-affiliations (and those without PTSD symptomology or high …
Novice Teachers' Perceptions Of Clinical Experience And Their Preparedness To Teach In High-Need Urban Schools, Robin D. Renelus
Novice Teachers' Perceptions Of Clinical Experience And Their Preparedness To Teach In High-Need Urban Schools, Robin D. Renelus
UNF Graduate Theses and Dissertations
This hermeneutic phenomenological study examined novice teachers’ perceptions of how clinical experiences in a teacher preparation program prepared them to teach in high-need urban schools. The study included 12 novice teachers with three or fewer years of teaching experience who completed their clinical experience at the same university in Northeast Florida. Data were collected using Seidman’s (2019) three-interview approach, which explored participants’ backgrounds, day-to-day teaching experiences, and reflections on their sense of preparedness. Data were analyzed to develop textural descriptions of what participants experienced and structural descriptions of how those experiences were shaped (Moustakas, 1994).
Participants described clinical experiences as …
From Preparation To Practice: A Study Of Assistant Principals After Completion Of An Aspiring Assistant Principal Preparation Program, Mallory L. Mcconnell
From Preparation To Practice: A Study Of Assistant Principals After Completion Of An Aspiring Assistant Principal Preparation Program, Mallory L. Mcconnell
UNF Graduate Theses and Dissertations
Leadership programs and readiness in schools, particularly those in Florida, is well studied. However, few studies have investigated how current assistant principals who have completed Clay County District School’s Aspiring Assistant Principal Program describe their experiences, believe the program has prepared them for the realities of school leadership, or identify the most impactful elements that have supported their leadership development. This case study seeks to collect foundational research knowledge by analyzing data from the program, participants, and key facilitators. Using a sampling of current assistant principals who have completed the Aspiring Assistant Principal Program, this research examines the results in …
Genetic Diversity Of Cryptosporidium Species In New York State, Kimberly A. Mergen
Genetic Diversity Of Cryptosporidium Species In New York State, Kimberly A. Mergen
Electronic Theses & Dissertations (2024 - present)
The knowledge regarding Cryptosporidium infections in New York State (NYS) is severely lacking in two ways: 1) there are currently no NYS-based data regarding the subtypes of Cryptosporidium parvum and Cryptosporidium hominis, which are the two most prevalent species that infect humans and 2) information regarding uncommon Cryptosporidium species that infect the New York population is also unavailable. Filling these gaps concerning this pathogenic parasite would provide a substantial amount of information when considering public health, outbreak investigations, and prevention measures. Therefore, improving Cryptosporidium subtype and species surveillance in NYS will aid in prevention and control efforts as well …
As If It Were Food: A Prose Translation Of The Old English Genesis B, Kane R. Malone
As If It Were Food: A Prose Translation Of The Old English Genesis B, Kane R. Malone
Electronic Theses & Dissertations (2024 - present)
The anonymous Old English poem known as “Genesis B” comes down to us as one of the most inherently human retellings of the Fall of Adam and Eve. Despite this, the piece is seldom read by the average twenty-first century middle-school learner. The poem, originally penned in Old English, has been translated into modern English numerous times, yet as I read through a variety of these translations, they all seemed to downplay the human element which I found intriguing. Thus, I created my own translation of “Genesis B” with a more general audience in mind, looking to create something that …
Entropic Foundation Of Finance And Physics: Securities Price Dynamics And Quantum Theory, Mohammad Abedi
Entropic Foundation Of Finance And Physics: Securities Price Dynamics And Quantum Theory, Mohammad Abedi
Electronic Theses & Dissertations (2024 - present)
In many scientific and financial contexts, we must reason and make predictions under conditions of incomplete information. This dissertation develops Entropic Dynamics (ED) as a unified framework for deriving dynamical laws directly from principles of inference. Within this approach, probability distributions represent states of knowledge, and their evolution is determined through entropy maximization subject to relevant constraints. This leads to a novel concept of entropic time and a formulation of dynamics as an inferential process. In this talk, I will present how ED provides a common foundation across multiple domains. In physics, quantum dynamics for particles and scalar fields in …
Human Vaccine Hesitancy Spillover In The Field Of Veterinary Medicine: A Systematic Narrative Review Of Impacts And Veterinary Responses, Allison Schimpf
Human Vaccine Hesitancy Spillover In The Field Of Veterinary Medicine: A Systematic Narrative Review Of Impacts And Veterinary Responses, Allison Schimpf
HEAL Project Outputs
Human vaccine hesitancy spillover in the veterinary field is a relatively new concept that has gained traction since the COVID-19 pandemic. Concerns about vaccine safety have increased among pet owners leading to questions about the potential impacts of reduced vaccination and how veterinarians can address these attitudes. A systematic search strategy following PRISMA 2020 guidelines was used with 3 different databases to collect peer-reviewed research articles from 2022 until now. The initial search yielded 376 articles for review and 11 were included after screening. Articles were analyzed using a narrative review format. Results showed that pet owners are more vaccine …
Wherefore Art Thou Competitors? How Situational Affordances Help Differentiate Among Prosocials, Individualists, And Competitors, Y. Liu, A.W. Stivers, R.O. Murphy, N.J. Van Doesum, J. Joireman, M. Gallucci, E. Aharonov-Majar, U. Athenstaedt, L. Bai, R. Böhm, N.R. Buchan, X.-P. Chen, K.B. Dumont, J.B. Engelmann, Li, Norman P., H. Euh, S. Fiedler, J. Friesen, S. Gächter, C. Garcia
Wherefore Art Thou Competitors? How Situational Affordances Help Differentiate Among Prosocials, Individualists, And Competitors, Y. Liu, A.W. Stivers, R.O. Murphy, N.J. Van Doesum, J. Joireman, M. Gallucci, E. Aharonov-Majar, U. Athenstaedt, L. Bai, R. Böhm, N.R. Buchan, X.-P. Chen, K.B. Dumont, J.B. Engelmann, Li, Norman P., H. Euh, S. Fiedler, J. Friesen, S. Gächter, C. Garcia
Research Collection School of Social Sciences
The Triple Dominance Measure (choosing between prosocial, individualistic, and competitive options) and the Slider Measure (“sliding” between various orientations, for example, from individualistic to prosocial) are two widely used techniques to measure social value orientation, that is, the weight individuals assign to own and others’ outcomes in interdependent situations. Surprisingly, there is only moderate correspondence between these measures, but it is unclear why and what the implications are for identifying individual differences in social value orientation. Using a dataset of 8021 participants from 31 countries and regions, this study revealed that the Slider Measure identified fewer competitors than the Triple …
Artificial Intelligence, Fundamental Motives, And Evolutionary Mismatch, Amy J. Lim, Jose. C. Yong, Edison Sora Tan
Artificial Intelligence, Fundamental Motives, And Evolutionary Mismatch, Amy J. Lim, Jose. C. Yong, Edison Sora Tan
Research Collection School of Social Sciences
In recent years, the intersection of artificial intelligence (AI) and psychology has garnered unprecedented attention, particularly following the advent of generative AI tools in 2022. These tools, capable of producing human-like text, images, and even deepening our understanding of cognitive processes, have not only captured the public imagination but also sparked new concerns and debates within the psychological community. While AI has been a subject of research for decades, the emergence of its generative capabilities has truly thrust AI into the spotlight. This article explores how these advancements are reshaping our understanding of human cognition and behavior, as well as …
Active Synchronous Participation In Online University Courses: Areview, María Dolores Rueda Montero
Active Synchronous Participation In Online University Courses: Areview, María Dolores Rueda Montero
Capítulos de libros
This work explores the nature of synchronous active participation in online university education, focusing on its pedagogical value, challenges, and effective design strategies. While asynchronous learning dominates online higher education due to flexibility, the literature consistently highlights its limitations in engagement, motivation, and social connection. Synchronous active participation can compensate for these constraints by fostering social presence, sustained attention, and real-time interaction, especially when it is intentionally designed and facilitated. This study examines key themes such as webcam use, multimodal participation, community building, instructional design, and instructor digital competence. Findings show that non-use of cameras often reflects privacy, anxiety, or …
Developing Your Research Project: Writing An Annotated Bibliography, Fabiola Ceballos-Durham
Developing Your Research Project: Writing An Annotated Bibliography, Fabiola Ceballos-Durham
Open Educational Resources
Students build the foundation for a criminal justice research project by evaluating and summarizing scholarly articles and websites in an APA-style annotated bibliography.
Creating A Social Media Campaign, Alexa Capeloto
Creating A Social Media Campaign, Alexa Capeloto
Open Educational Resources
Students research an issue related to social good and apply visual, news, and digital literacy skills to design an original image and a proposed social media campaign.
Writing To Different Audiences For Different Purposes, Kim Liao
Writing To Different Audiences For Different Purposes, Kim Liao
Open Educational Resources
Students research a recent technology and write three pieces for different audiences: an informational guide for nonexperts, an analytical memo for professionals, and a public-facing op-ed. They revise these pieces into a portfolio and reflect on how their writing choices serve each audience and purpose.
Toxicology Case Study Model, Ana Pego
Toxicology Case Study Model, Ana Pego
Open Educational Resources
Graduate students apply laboratory skills to an authentic forensic toxicology case by interpreting evidence, recommending analytical methods, and presenting a critical group assessment.
Challenges And Best Practices For The Development Of Coastal Hazard Decision Support Tools, Noah Hallisey
Challenges And Best Practices For The Development Of Coastal Hazard Decision Support Tools, Noah Hallisey
Open Access Dissertations
There is growing interest in developing Decision Support Tools (DSTs) supporting emergency managers and other decision-makers during coastal storm events. Yet many tools fail to inform decision-making due to challenges associated with their development and transition into operational tools for real-time decision-making. This dissertation investigates these challenges and offers best practices for their development and implementation for real-world decision-making through a literature review, interviews with subject matter experts in the United States, and a real-world case study.
Manuscript 1 reviews existing published literature to understand whether and how tool developers are incorporating emergency managers in the development of DSTs and …
You’Re Gonna Be Popular: A Semiotic Exploration Of Meaningful Tools Used To Promote Popular Music Artists, Maya Raye Kurth
You’Re Gonna Be Popular: A Semiotic Exploration Of Meaningful Tools Used To Promote Popular Music Artists, Maya Raye Kurth
Masters Theses
I have been to dozens of concerts, but after experiencing The Era’s Tour I became a Swiftie so quickly and passionately that I was looking for comparable concerts and fan experiences and found very few. It made me wonder how and why this fan experience stuck with me and what made it so special. With that question in mind, I started this project with the question of how successful indie music is marketed.
To answer this question, I used semiotics as the driving theory behind this study. Semiotics allowed me to establish a binary between organic and manufactured and allowed …
The Role Of International Student Office Directors In Facilitating The Transitional Adjustment Of International Students In U.S Higher Education, Agnes Afi Yigah
The Role Of International Student Office Directors In Facilitating The Transitional Adjustment Of International Students In U.S Higher Education, Agnes Afi Yigah
Masters Theses
This qualitative study explored how International Student Office Directors facilitate the transitional adjustment of international students in U.S. higher education institutions. Guided by Schlossberg’s Transition Theory (1981) and Schlossberg’s Mattering and Marginality Theory (1989), this study examined the challenges international students face, the support strategies implemented by International Student Office Directors, and the institutional factors influencing student adjustment and well-being. International students experience challenges related to housing and logistical adjustment, financial and immigration-related stressors, academic system adjustment and self-advocacy, and social integration and emotional adjustment. Proactive and holistic support approaches, including pre-arrival communication, orientation programs, academic support, emotional support, and …
De Novo And Inherited Dominant Variants In U4 And U6 Snrna Genes Cause Retinitis Pigmentosa, Mathieu Quinodoz, Kim Rodenburg, Zuzana Cvackova, Karolina Kaminska, Suzanne E De Bruijn, Ana Belén Iglesias-Romero, Erica G M Boonen, Mukhtar Ullah, Nick Zomer, Marc Folcher, Jacques Bijon, Lara K Holtes, Stephen H Tsang, Zelia Corradi, K Bailey Freund, Stefanida Shliaga, Daan M Panneman, Rebekkah J Hitti-Malin, Manir Ali, Ala'a Altalbishi, Sten Andréasson, Georg Ansari, Gavin Arno, Galuh D N Astuti, Carmen Ayuso, Radha Ayyagari, Sandro Banfi, Eyal Banin, Tahsin Stefan Barakat, Mirella T S Barboni, Miriam Bauwens, Tamar Ben-Yosef, Virginie Bernard, David G Birch, Pooja Biswas, Fiona Blanco-Kelly, Beatrice Bocquet, Camiel J F Boon, Kari Branham, Dominique Bremond-Gignac, Alexis Ceecee Britten-Jones, Kinga M Bujakowska, Cyril Burin Des Roziers, Elizabeth L Cadena, Giacomo Calzetti, Francesca Cancellieri, Luca Cattaneo, Naomi Chadderton, Peter Charbel Issa, Luísa Coutinho-Santos, Stephen P Daiger, Elfride De Baere, Marieke De Bruyne, Berta De La Cerda, John N De Roach, Julie De Zaeytijd, Ronny Derks, Claire-Marie Dhaenens, Lubica Dudakova, Jacque L Duncan, G Jane Farrar, Nicolas Feltgen, Beau J Fenner, Lidia Fernández-Caballero, Juliana M Ferraz Sallum, Simone Gana, Alejandro Garanto, Jessica C Gardner, Christian Gilissen, Roser Gonzàlez-Duarte, Kensuke Goto, Sam Griffiths-Jones, Tobias B Haack, Lonneke Haer-Wigman, Alison J Hardcastle, Takaaki Hayashi, Elise Héon, Lies H Hoefsloot, Alexander Hoischen, Josephine P Holtan, Carel B Hoyng, Manuel Benjamin B Ibanez, Chris F Inglehearn, Takeshi Iwata, Brynjar O Jensson, Kaylie Jones, Vasiliki Kalatzis, Smaragda Kamakari, Marianthi Karali, Ulrich Kellner, Caroline C W Klaver, Krisztina Knézy, Robert K Koenekoop, Susanne Kohl, Taro Kominami, Laura Kühlewein, Tina M Lamey, Rina Leibu, Bart P Leroy, Petra Liskova, Irma Lopez, Victor R De J López-Rodríguez, Quinten Mahieu, Omar A Mahroo, Gaël Manes, Luke Mansard, M Pilar Martín-Gutiérrez, Nelson Martins, Laura Mauring, Martin Mckibbin, Terri L Mclaren, Isabelle Meunier, Michel Michaelides, José M Millán, Kei Mizobuchi, Rajarshi Mukherjee, Zoltán Zsolt Nagy, Kornelia Neveling, Monika Ołdak, Michiel Oorsprong, Yang Pan, Anastasia Papachristou, Antonio Percesepe, Maximilian Pfau, Eric A Pierce, Emily Place, Raj Ramesar, Francis Ramond, Florence Andrée Rasquin, Gillian I Rice, Lisa Roberts, María Rodríguez-Hidalgo, Javier Ruiz-Ederra, Ataf H Sabir, Ai Fujita Sajiki, Ana Isabel Sánchez-Barbero, Asodu Sandeep Sarma, Riccardo Sangermano, Cristina M Santos, Margherita Scarpato, Hendrik P N Scholl, Dror Sharon, Sabrina G Signorini, Francesca Simonelli, Ana Berta Sousa, Maria Stefaniotou, Kari Stefansson, Katarina Stingl, Akiko Suga, Patrick Sulem, Lori S Sullivan, Viktória Szabó, Jacek P Szaflik, Gita Taurina, Alberta A H J Thiadens, Carmel Toomes, Viet H Tran, Miltiadis K Tsilimbaris, Pavlina Tsoka, Veronika Vaclavik, Marie Vajter, Sandra Valeina, Enza Maria Valente, Casey Valentine, Rebeca Valero, Sophie Valleix, Joseph Van Aerschot, L Ingeborgh Van Den Born, Mattias Van Heetvelde, Virginie J M Verhoeven, Andrea L Vincent, Andrew R Webster, Laura Whelan, Bernd Wissinger, Georgia G Yioti, Kazutoshi Yoshitake, Juan C Zenteno, Roberta Zeuli, Theresia Zuleger, Chaim Landau, Allan I Jacob, Siying Lin, Frans P M Cremers, Winston Lee, Jamie M Ellingford, David Stanek, Susanne Roosing, Carlo Rivolta
De Novo And Inherited Dominant Variants In U4 And U6 Snrna Genes Cause Retinitis Pigmentosa, Mathieu Quinodoz, Kim Rodenburg, Zuzana Cvackova, Karolina Kaminska, Suzanne E De Bruijn, Ana Belén Iglesias-Romero, Erica G M Boonen, Mukhtar Ullah, Nick Zomer, Marc Folcher, Jacques Bijon, Lara K Holtes, Stephen H Tsang, Zelia Corradi, K Bailey Freund, Stefanida Shliaga, Daan M Panneman, Rebekkah J Hitti-Malin, Manir Ali, Ala'a Altalbishi, Sten Andréasson, Georg Ansari, Gavin Arno, Galuh D N Astuti, Carmen Ayuso, Radha Ayyagari, Sandro Banfi, Eyal Banin, Tahsin Stefan Barakat, Mirella T S Barboni, Miriam Bauwens, Tamar Ben-Yosef, Virginie Bernard, David G Birch, Pooja Biswas, Fiona Blanco-Kelly, Beatrice Bocquet, Camiel J F Boon, Kari Branham, Dominique Bremond-Gignac, Alexis Ceecee Britten-Jones, Kinga M Bujakowska, Cyril Burin Des Roziers, Elizabeth L Cadena, Giacomo Calzetti, Francesca Cancellieri, Luca Cattaneo, Naomi Chadderton, Peter Charbel Issa, Luísa Coutinho-Santos, Stephen P Daiger, Elfride De Baere, Marieke De Bruyne, Berta De La Cerda, John N De Roach, Julie De Zaeytijd, Ronny Derks, Claire-Marie Dhaenens, Lubica Dudakova, Jacque L Duncan, G Jane Farrar, Nicolas Feltgen, Beau J Fenner, Lidia Fernández-Caballero, Juliana M Ferraz Sallum, Simone Gana, Alejandro Garanto, Jessica C Gardner, Christian Gilissen, Roser Gonzàlez-Duarte, Kensuke Goto, Sam Griffiths-Jones, Tobias B Haack, Lonneke Haer-Wigman, Alison J Hardcastle, Takaaki Hayashi, Elise Héon, Lies H Hoefsloot, Alexander Hoischen, Josephine P Holtan, Carel B Hoyng, Manuel Benjamin B Ibanez, Chris F Inglehearn, Takeshi Iwata, Brynjar O Jensson, Kaylie Jones, Vasiliki Kalatzis, Smaragda Kamakari, Marianthi Karali, Ulrich Kellner, Caroline C W Klaver, Krisztina Knézy, Robert K Koenekoop, Susanne Kohl, Taro Kominami, Laura Kühlewein, Tina M Lamey, Rina Leibu, Bart P Leroy, Petra Liskova, Irma Lopez, Victor R De J López-Rodríguez, Quinten Mahieu, Omar A Mahroo, Gaël Manes, Luke Mansard, M Pilar Martín-Gutiérrez, Nelson Martins, Laura Mauring, Martin Mckibbin, Terri L Mclaren, Isabelle Meunier, Michel Michaelides, José M Millán, Kei Mizobuchi, Rajarshi Mukherjee, Zoltán Zsolt Nagy, Kornelia Neveling, Monika Ołdak, Michiel Oorsprong, Yang Pan, Anastasia Papachristou, Antonio Percesepe, Maximilian Pfau, Eric A Pierce, Emily Place, Raj Ramesar, Francis Ramond, Florence Andrée Rasquin, Gillian I Rice, Lisa Roberts, María Rodríguez-Hidalgo, Javier Ruiz-Ederra, Ataf H Sabir, Ai Fujita Sajiki, Ana Isabel Sánchez-Barbero, Asodu Sandeep Sarma, Riccardo Sangermano, Cristina M Santos, Margherita Scarpato, Hendrik P N Scholl, Dror Sharon, Sabrina G Signorini, Francesca Simonelli, Ana Berta Sousa, Maria Stefaniotou, Kari Stefansson, Katarina Stingl, Akiko Suga, Patrick Sulem, Lori S Sullivan, Viktória Szabó, Jacek P Szaflik, Gita Taurina, Alberta A H J Thiadens, Carmel Toomes, Viet H Tran, Miltiadis K Tsilimbaris, Pavlina Tsoka, Veronika Vaclavik, Marie Vajter, Sandra Valeina, Enza Maria Valente, Casey Valentine, Rebeca Valero, Sophie Valleix, Joseph Van Aerschot, L Ingeborgh Van Den Born, Mattias Van Heetvelde, Virginie J M Verhoeven, Andrea L Vincent, Andrew R Webster, Laura Whelan, Bernd Wissinger, Georgia G Yioti, Kazutoshi Yoshitake, Juan C Zenteno, Roberta Zeuli, Theresia Zuleger, Chaim Landau, Allan I Jacob, Siying Lin, Frans P M Cremers, Winston Lee, Jamie M Ellingford, David Stanek, Susanne Roosing, Carlo Rivolta
Faculty, Staff and Student Publications
Small nuclear RNAs (snRNAs) combine with specific proteins to generate small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. U4 snRNA forms a duplex with U6 and, together with U5, contributes to the tri-snRNP spliceosomal complex. Variants in RNU4-2, which encodes U4, have recently been implicated in neurodevelopmental disorders. Here we show that heterozygous inherited and de novo variants in RNU4-2 and in four RNU6 paralogs (RNU6-1, RNU6-2, RNU6-8 and RNU6-9), which encode U6, recur in individuals with nonsyndromic retinitis pigmentosa (RP), a genetic disorder causing progressive blindness. These variants cluster within the three-way junction of the U4/U6 duplex, …
Geospatial Disparities In Adolescent Mental Health Resources: School- And Community-Level Evidence From Travis County, Texas, Sharon V Munroe, Jingjing Gao, Gayla Ferguson, Muinat Abolore Idris, Eric C Jones
Geospatial Disparities In Adolescent Mental Health Resources: School- And Community-Level Evidence From Travis County, Texas, Sharon V Munroe, Jingjing Gao, Gayla Ferguson, Muinat Abolore Idris, Eric C Jones
Faculty, Staff and Student Publications
Background: Adolescents in the United States face growing mental health challenges, with nearly one in three high school students reporting poor mental health in the past 30 days. Schools increasingly serve as key access points for mental health care. However, geographic disparities in access to school-based mental health services remain underexplored.
Purpose: This study examines the spatial distribution of adolescent mental health resources in Travis County, Texas, and evaluates how school- and community-level factors are associated with the presence of on-site school social workers.
Methods: School locations, enrollment data, and the presence of on-site social workers were mapped and analyzed …
Understanding Ehlers-Danlos Syndrome: A Claims-Based Analysis Of Healthcare Cost Patterns, Samson A Oyediran, Youngran Kim, Zhanna Novikov, Trudy M Krause
Understanding Ehlers-Danlos Syndrome: A Claims-Based Analysis Of Healthcare Cost Patterns, Samson A Oyediran, Youngran Kim, Zhanna Novikov, Trudy M Krause
Faculty, Staff and Student Publications
Background: Ehlers-Danlos Syndrome (EDS) is a rare connective tissue disorder associated with substantial clinical complexity and healthcare utilization. Despite increasing recognition of EDS, little is known about its economic burden in the United States.
Objective: To assess the all-cause healthcare costs for individuals with newly diagnosed EDS during the pre-diagnosis year and the first 2 years post-diagnosis.
Methods: A retrospective cohort study was conducted using the Merative™ MarketScan® Commercial Claims and Encounters Database (2016-2022). Newly diagnosed patients were identified using ICD-10-CM codes, with the first observed diagnosis defined as the index date. Continuous enrollment for 12 months pre-index and 24 …
Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data, Joonha Chang, Wenyaw Chan
Latent Classification Of Time-Dependent Transition Rates In Longitudinal Binary Outcome Data, Joonha Chang, Wenyaw Chan
Faculty, Staff and Student Publications
Continuous-time Markov chain (CTMC) models and latent classification methods are commonly used to analyze longitudinal categorical outcomes in medical research. While CTMC models are popular for their simplicity and effectiveness, their assumption of constant transition rates presents limitations in capturing dynamic behaviors. To address this, non-homogeneous continuous-time Markov chains (NH-CTMCs) have been developed, incorporating time-varying transition rates to enhance model flexibility. In this study, we leverage closed-form transition probabilities for a fully ergodic two-state NH-CTMC model and propose a latent class clustering approach to identify heterogeneous transition rate patterns within the population. We emphasize the potential advantages of these models …
“If He Did It, I Can Do It, Too. I Can Change My Life Around”: The Social Model Of Recovery Within The Context Of Recovery Homes Accepting Residents Prescribed Medications For Opioid Use Disorder, Jodie M Dewey, Kathryn R Gallardo, Meenakshi S Subbaraman, Amy A Mericle
“If He Did It, I Can Do It, Too. I Can Change My Life Around”: The Social Model Of Recovery Within The Context Of Recovery Homes Accepting Residents Prescribed Medications For Opioid Use Disorder, Jodie M Dewey, Kathryn R Gallardo, Meenakshi S Subbaraman, Amy A Mericle
Faculty, Staff and Student Publications
Introduction: This paper provides an in-depth examination of examines four recovery residences, that serve individuals prescribed medications for opioid use disorder (MOUD). The study has two primary aims: first, to deepen understanding of how recovery residences adopt and operationalize Social Model of Recovery principles; and second, to identify gaps in staff integration of residents receiving MOUD-gaps that may either support or undermine the integrity of the social model within these settings.
Methods: We conducted semi-structured interviews with 17 residents receiving MOUD living in four participating recovery homes. The interviews were conducted between August 2022 and January 2024 using a semi-structured …
Corrigendum To 'Continuous Vital Sign Monitoring On Surgical Wards: The Cosmos Pilot, Nikola Anusic, Alper Gulluoglu, Elyad Ekrami, Edward J Mascha, Shuyi Li, René Coffeng, Alparslan Turan, Amber Clemens, Christine Perez, John W Beard, Daniel I Sessler, Cosmos Pilot Investigators
Corrigendum To 'Continuous Vital Sign Monitoring On Surgical Wards: The Cosmos Pilot, Nikola Anusic, Alper Gulluoglu, Elyad Ekrami, Edward J Mascha, Shuyi Li, René Coffeng, Alparslan Turan, Amber Clemens, Christine Perez, John W Beard, Daniel I Sessler, Cosmos Pilot Investigators
Faculty, Staff and Student Publications
Study objectives: Alerts for vital sign abnormalities seek to identify meaningful patient instability while limiting alarm fatigue. Optimal vital sign alarm settings for postoperative patients remain unknown, as is whether alerts lead to effective clinical responses reducing vital sign disturbances. We conducted a 2-phase pilot study to identify thresholds and delays and test the hypothesis that alerts from continuous monitoring reduce the duration of vital sign abnormalities.
Design: Two-phase pilot.
Patients: 250 adults having major non-cardiac surgery.
Setting: Surgical wards.
Intervention: All patients had routine vital sign monitoring by nurses at 4-h intervals. We initially continuously recorded clinician-blinded saturation, heart …
Pregnancy And Breastfeeding Are Associated With Less Later-Life Cognitive Decline In A Longitudinal, Prospective Cohort, Molly M Fox, Jennifer E Bramen, Dayoon Kwon, Mark A Espeland, Yijia Sun, Li Zhang, Aladdin H Shadyab, Ramon Casanova, Joann E Manson, Marcus Y Chang, Verna R Porter, Leslie V Farland, Qian Xiao, Robert A Wild, Prabha Siddarth, Carolyn J Crandall
Pregnancy And Breastfeeding Are Associated With Less Later-Life Cognitive Decline In A Longitudinal, Prospective Cohort, Molly M Fox, Jennifer E Bramen, Dayoon Kwon, Mark A Espeland, Yijia Sun, Li Zhang, Aladdin H Shadyab, Ramon Casanova, Joann E Manson, Marcus Y Chang, Verna R Porter, Leslie V Farland, Qian Xiao, Robert A Wild, Prabha Siddarth, Carolyn J Crandall
Faculty, Staff and Student Publications
Introduction: The brains of female mammals evolved to undergo structural and functional changes during pregnancy and lactation, equipping them for motherhood. However, long-term cognitive health implications of these adaptations in women are poorly understood.
Methods: In the Women's Health Initiative (WHI) Memory Study (WHIMS; n = 7427) and WHI Study of Cognitive Aging (WHISCA; n = 2304), postmenopausal women completed reproductive history interviews, annual global cognitive assessment from mean age 70 for up to 13 years, and multi-domain cognitive testing for up to 8 years.
Results: Each additional month pregnant was associated with higher scores of global cognition. Each additional …
Artificial Light At Night Extends Pollen Season And Elevates Allergen Exposure, Brandt Geist, Lin Meng, Daniel S W Katz, Huidong Li, Franz Hölker, Qian Xiao
Artificial Light At Night Extends Pollen Season And Elevates Allergen Exposure, Brandt Geist, Lin Meng, Daniel S W Katz, Huidong Li, Franz Hölker, Qian Xiao
Faculty, Staff and Student Publications
Artificial light at night (ALAN), a growing environmental stressor in urban ecosystems, disrupts natural light-dark cycles and alters plant phenological events such as leaf-out and flowering. However, the extent to which ALAN influences airborne pollen season timing and exacerbates allergy-related health risks remains largely understudied. This study investigates how ALAN influences the timing and duration of the airborne pollen season across the Northeastern United States from 2012 to 2023 and the consequences of allergenic pollen exposure. Using daily pollen concentrations from the National Allergy Bureau, ALAN data from the Visible Infrared Imaging Radiometer Suite product, and gridded Daymet climate data, …
Plasma Proteomic Profile Of Dietary Potassium And Incident Ckd, Jiaqi Yang, Lauren Bernard, Jingsha Chen, Valerie K Sullivan, Bing Yu, Eugene P Rhee, Paul A Welling, Casey M Rebholz
Plasma Proteomic Profile Of Dietary Potassium And Incident Ckd, Jiaqi Yang, Lauren Bernard, Jingsha Chen, Valerie K Sullivan, Bing Yu, Eugene P Rhee, Paul A Welling, Casey M Rebholz
Faculty, Staff and Student Publications
Background:: There is a need for objective biomarkers of dietary potassium. The mechanisms through which dietary potassium influences kidney health are incompletely understood.
Methods:: Atherosclerosis Risk in Communities study participants at visit 3 (1993–1995) with dietary and proteomics data were randomly divided into discovery (N=6,814) and replication (N=3,380) sets. We examined associations between dietary potassium and 4,955 aptamers using multivariable linear regression, adjusting for sociodemographic factors, health behaviors, and estimated glomerular filtration rate, with a false discovery rate of 0.05. Then, we tested the prospective associations between potassium-related proteins and incident chronic kidney disease (CKD).
Results:: …
Examining Tobacco Prevention And Cessation Among Dental Students In Southern Italy, Olga Di Fede, Samuel Tundealao, David Okuji, Gaetano La Mantia, Irene Tamí-Maury
Examining Tobacco Prevention And Cessation Among Dental Students In Southern Italy, Olga Di Fede, Samuel Tundealao, David Okuji, Gaetano La Mantia, Irene Tamí-Maury
Faculty, Staff and Student Publications
Background: Previous studies have reported that tobacco use among healthcare providers (HCPs) has a negative impact on their beliefs and attitudes toward tobacco prevention and control measures. However, little is known about these among Italian dental students. Therefore, this single-site study examined tobacco use behaviors and the knowledge, attitudes, and perceptions of dental students at a public university in Southern Italy regarding tobacco prevention and control.
Methods: A cross-sectional study through an online survey was conducted among 115 students aged 18 + years enrolled in dentistry and dental hygiene programs at a Southern Italy university. Chi-squared, Fisher's, t-tests, and …