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Blood Product Transfusion And Coagulopathy In Children With Traumatic Brain Injury: A Narrative Review., Robert Marcel T. Huibonhoa, Niranjan Vijayakumar, Daniel Kelly, Oliver Karam, Madhuradhar Chegondi

Manuscripts, Articles, Book Chapters and Other Papers

Traumatic brain injury (TBI) is a leading cause of critical illness and mortality in children. Transfusion of blood products, a common intervention in the management of pediatric TBI, has important implications for related principles, including trauma-induced coagulopathy, cerebral perfusion, and cerebral oxygen delivery. Knowledge gaps persist due to the limited availability of pediatric-specific data regarding blood product transfusion in TBI. In particular, there is a lack of prospective studies defining appropriate specific laboratory thresholds and transfusion targets, as well as insufficient evidence to guide the weighing of potential benefits against transfusion-related risks in this population. Although blood product transfusion in …

Grover's Disease: A Review Of The Current Treatment Options, Dustin Ross, Dmsc, Mph, Pa-C

Lynchburg Journal of Medical Science

Grover’s disease, also known as transient acantholytic dermatosis, is an uncommon dermatologic condition characterized by pruritic papulovesicular eruptions that predominantly affect the trunk of older adults. Although the disease is often self-limited, it may significantly impair quality of life. This review summarizes treatment options and emerging therapies for Grover’s disease reported in the literature since 2019. A comprehensive search of PubMed and MEDLINE identified 1,068 records, of which thirteen publications met inclusion criteria, including one systematic review, one narrative review, one nonrandomized controlled study, nine case reports, and one fact sheet, representing a total of 337 patients. The literature demonstrates …

Growing Wise: Proverbs 2:1–11 As A Formative Paradigm For Jesuit Formation, Carlos Cesar Barbosa Silva

Loyola Papers

This article offers a theological reading of Proverbs 2:1-11 as a sapiential text on the formation of the human person in the religious life and explores its implications for Jesuit formation. Through attention to the literary and theological movement of the passage, the article identifies four formative movements: the active search for Wisdom, its reception as a divine gift, its ethical expression, and its interior integration. These movements provide a biblical lens for examining three risks in Jesuit formation: overprotection, careerism, and sterile intellectualism. The article argues that in Proverbs 2:1-11, Wisdom is a gift that transforms the heart and …

The Internally Displaced Persons In Fada N’Gourma Diocese, Burkina Faso: A Study On Human Dignity In The Light Of Catholic Social Teaching, Wendpouiré Améline Kabore

Loyola Papers

This study explores the experiences of the Internally Displaced Persons in the Diocese of Fada N’Gourma in Burkina Faso amid terrorism. It uses the See-Judge- Act method of Catholic Social Teaching to investigate the challenges to IDPs’ dignity. The observations reveal an IDP population victimized by discrimination and neglect within the host communities, emphasizing the moral imperative to uphold dignity. The research contributes to theological reflection on displacement and dignity while highlighting the Church’s unique faith-based humanitarian assistance, free from proselytism and political agendas despite the structural and practical limitations and difficulties.

Martyrdom And The Call To Daily Witness In The Teaching Of Pope John Paul Ii, Nguyen Van Tam

Loyola Papers

This article explores Pope John Paul II’s understanding of martyrdom and its meaning for Christian life and witness today. Drawing especially on the encyclical Veritatis Splendor and the post-synodal apostolic exhortation Vita Consecrata, it presents martyrdom as the fullest expression of fidelity to Christ, rooted in his Paschal Mystery and sustained by grace, truth, love, and hope. The article examines the Christological, anthropological, ecclesiological, and eschatological dimensions of martyrdom. It also highlights John Paul II’s understanding of “daily martyrdom,” through which Christians are called to give themselves faithfully to Christ in ordinary life. In this sense, martyrdom remains a living …

Hope Amidst Desolation: A Socio-Historical And Theological Reflection On Myanmar Catholicism, Set Paing Tun

Loyola Papers

This research paper examines the profound spiritual resilience of Catholics in Myanmar amid ongoing socio-political turmoil, including the coup d’état, civil war, and rising inflation. Utilizing socio-historical and literary analyses, this paper investigates how Psalm 23 functions as a vital source of hope and consolation, fostering resilience among Myanmar Catholics experiencing uncertainty and desolation. The analysis highlights Psalm 23:4, which states, “even though I walk through the darkest valley, I fear no evil for you are with me,” and explores the metaphor of God as a shepherd who provides and protects, resonating with the lived experiences of believers facing suffering …

Medieval Canon Law On Catechesis And Christian Formation, Enrico C. Eusebio Jr.

Loyola Papers

By reconstructing medieval catechetical legislation, this paper presents a distinct field of research within the Church’s canonical system, one long overlooked in canonical historical study, which has long focused on matrimonial, liturgical, or disciplinary norms. Drawing primarily from conciliar and synodal canons and episcopal directives, this study demonstrates that long before the Council of Trent, the Church was already systematically legislating on the teaching of Christian doctrine and Christian formation. As Church practice shifted from adult to infant baptism, catechetical formation moved from the holistic pre-baptismal catechumenate to doctrinal and moral instruction through the catechetical sermons of bishops, parish priests, …

Desire For The Good: A Philosophical Roadmap Through Spacetime, Bertrand Leong

Loyola Papers

No abstract provided.

Full Issue, Volume 7, Issue 2

Loyola Papers

No abstract provided.

Broad Laboratory Testing Does Not Show Utility For Telogen Effluvium: A Retrospective Analysis Of 22-Million Laboratory Results Using Trinetx, Zachary J.K. Neubauer, Shari R. Lipner

Student Papers, Posters & Projects

No abstract provided.

Proton Versus Photon Radiotherapy For Patients With Oropharyngeal Cancer In The Usa: A Multicentre, Randomised, Open-Label, Non-Inferiority Phase 3 Trial, Steven J Frank, Paul M Busse, J Jack Lee, David I Rosenthal, Mike Hernandez, David M Swanson, Adam S Garden, G Brandon Gunn, Samir H Patel, James W Snider, Daniel J Ma, Jason K Molitoris, Nancy Y Lee, Upendra Parvathaneni, Mark W Mcdonald, Noah S Kalman, Alexander Lin, Nasiruddin Mohammed, Christina Henson, Christian Hyde, Gopal K Bajaj, Sanford R Katz, Roi Dagan, William H Morrison, Jay P Reddy, C David Fuller, Shalin J Shah, Jack Phan, Gregory M Chronowski, Lauren Mayo, Erich M Sturgis, Renata Ferrarotto, Xiaorong R Zhu, Xiaodong Zhang, Li Wang, Katherine A Hutcheson, Adel K El-Naggar, Amy C Moreno, Anna Lee, Michael T Spiotto, Neil D Gross, Stephen Y Lai, Jay J Liao, Jonathan Paly, Zhongxing Liao, Robert L Foote

Faculty, Staff and Student Publications

Background: Radiotherapy is an integral component of treatment for oropharyngeal cancer. Toxicity from the current state-of-the-art photon radiotherapy, intensity-modulated radiation therapy (IMRT), has prompted the search for alternative, less toxic therapies. One such alternative that might de-intensify treatment is proton therapy. In this trial, we aimed to directly compare IMRT with intensity-modulated proton therapy (IMPT), both concurrent with systemic therapy, hypothesising comparable disease control and survival and lower toxicity.

Methods: This randomised, multicentre, open-label, non-inferiority, phase 3 trial was conducted in 21 sites (cancer centres or universities) in the USA. Patients (aged ≥18 years) with stage III or stage IV …

Technology-Enabled Cognitive Behavioral Therapy For Insomnia (Cbt-I) In Older Adults With Mild Cognitive Impairment: Development And Feasibility Study, Hongtu Chen, Marta Pagán-Ortiz, Sara Romero Vincente, Emma Chapman, James Maxwell, Otis L. Owens, Sue E. Levkoff Scd, Msw, Sm

Faculty and Staff Publications

Background/Objectives: Mild Cognitive Impairment (MCI) is a transitional stage between normal aging and early dementia, affecting up to 20% of older adults. Sleep disturbances, particularly insomnia, affect around 60% of individuals with MCI, contributing to declines in cognitive and physical function. Although Cognitive Behavioral Therapy for Insomnia (CBT-I) is an evidence-based non-pharmacological treatment, few studies have adapted it for individuals with MCI. This pilot study developed and evaluated Slumber, a clinician-supported mobile CBT-I app tailored for older adults with MCI and insomnia. Methods: The study had three aims: (1) to develop the app for delivering CBT-I to individuals with …

Large-Scale Blood Pressure Gwas Accounting For Gene-Depression Interactions In 564,680 Individuals From Diverse Populations, Songmi Lee, Clint L Miller, Amy R Bentley, Michael R Brown, Pavithra Nagarajan, Raymond Noordam, John L Morrison, Karen Schwander, Kenneth Westerman, Minjung Kho, Aldi T Kraja, Paul S De Vries, Farah Ammous, Hughes Aschard, Traci M Bartz, Anh Do, Charles T Dupont, Mary F Feitosa, Valborg Gudmundsdottir, Xiuqing Guo, Sarah E Harris, Keiko Hikino, Zhijie Huang, Christophe Lefevre, Leo-Pekka Lyytikäinen, Yuri Milaneschi, Giuseppe Giovanni Nardone, Aurora Santin, Helena Schmidt, Botong Shen, Tamar Sofer, Quan Sun, Ye An Tan, Jingxian Tang, Sébastien Thériault, Peter J Van Der Most, Erin B Ware, Stefan Weiss, Wang Ya Xing, Chenglong Yu, Wei Zhao, Md Abu Yusuf Ansari, Pramod Anugu, John R Attia, Lydia A Bazzano, Joshua C Bis, Max Breyer, Brian Cade, Guanjie Chen, Stacey Collins, Janie Corley, Gail Davies, Marcus Dörr, Jiawen Du, Todd L Edwards, Tariq Faquih, Jessica D Faul, Alison E Fohner, Amanda M Fretts, Srushti Gangireddy, Adam Gepner, Mariaelisa Graff, Edith Hofer, Georg Homuth, Michelle M Hood, Xu Jie, Mika Kähönen, Sharon L R Kardia, Carrie A Karvonen-Gutierrez, Lenore J Launer, Daniel Levy, Maitreiyi Maheshwari, Lisa W Martin, Koichi Matsuda, John J Mcneil, Ilja M Nolte, Tomo Okochi, Laura M Raffield, Olli T Raitakari, Lorenz Risch, Martin Risch, Ana Diez Roux, Edward A Ruiz-Narvaez, Tom C Russ, Takeo Saito, Pamela J Schreiner, Rodney J Scott, James Shikany, Jennifer A Smith, Harold Snieder, Beatrice Spedicati, E Shyong Tai, Adele M Taylor, Kent D Taylor, Paola Tesolin, Rob M Van Dam, Rujia Wang, Wei Wenbin, Tian Xie, Jie Yao, Kristin L Young, Ruiyuan Zhang, Alan B Zonderman, Biobank Japan Project, Lifelines Cohort Study, Maria Pina Concas, David Conen, Simon R Cox, Michele K Evans, Ervin R Fox, Lisa De Las Fuentes, Ayush Giri, Giorgia Girotto, Hans J Grabe, Charles Gu, Vilmundur Gudnason, Sioban D Harlow, Elizabeth Holliday, Jonas B Jost, Paul Lacaze, Seunggeun Lee, Terho Lehtimäki, Changwei Li, Ching-Ti Liu, Alanna C Morrison, Kari E North, Brenda W J H Penninx, Patricia A Peyser, Michael M Province, Bruce M Psaty, Susan Redline, Frits R Rosendaal, Charles N Rotimi, Jerome I Rotter, Reinhold Schmidt, Xueling Sim, Chikashi Terao, David R Weir, Xiaofeng Zhu, Nora Franceschini, Jeffrey R O'Connell, Cashell E Jaquish, Heming Wang, Alisa Manning, Patricia B Munroe, Dabeeru C Rao, Han Chen, W James Gauderman, Laura J Bierut, Thomas W Winkler, Myriam Fornage

Faculty, Staff and Student Publications

Gene-environment interactions may enhance our understanding of blood pressure (BP) biology. We conducted a meta-analysis of multi-population genome-wide association studies (GWASs) of BP traits accounting for gene-depressive symptomatology (DEPR) interactions. Our study included 564,680 adults from 67 cohorts and four population backgrounds: African (5%), Asian (7%), European (85%), and Hispanic (3%). We discovered seven previously unreported BP loci showing gene-DEPR interaction. These loci mapped to genes implicated in neurogenesis (TGFA and CASP3), lipid metabolism (ACSL1), neuronal apoptosis (CASP3), and synaptic activity (CNTN6 and DBI). We also showed evidence for gene-DEPR interaction at nine known BP loci, further suggesting links between …

The Distribution Of Cadmium And Its Isotopes In The Subarctic Pacific, J. M. Malloy, H. R. Hunt, M. Sieber, S. Takano, H. Obata, T. M. Conway

Making Waves REU

• Cadmium (Cd) is a bioactive trace element that can act as a micronutrient, driving large scale chemical processes like photosynthesis and cellular respiration [1,2].
• The uptake of major nutrients is limited by dissolved iron (Fe) availability in high nutrient low chlorophyll (HNLC) surface regions like the subarctic Pacific [2,4].
• Upwelling of Cd-rich deepwater is a Cd source, in addition to riverine, atmospheric, and anthropogenic inputs [1].
• Dissolved cadmium isotopic compositions (δ114Cd) provide insight into the biogeochemical processes controlling Cd distributions throughout the water column, including biological uptake in surface waters, regeneration, and water mass mixing at depth.
• Here we present …

Association Of Neighborhood Economic Trajectories And Risk Of Mortality Among Older Adults, Erika Figueroa-Solis, Qian Xiao

Faculty, Staff and Student Publications

Background

Lower neighborhood socioeconomic status (SES) and decline in neighborhood SES have been linked to detrimental health outcomes, such as cardiovascular disease (CVD), cancer, and mortality. However, few studies have investigated distinct types of neighborhood economic trajectories in relation to mortality. We examined the association between the recently developed multidimensional measure of neighborhood trajectories and mortality in older adults enrolled in the National Institutes of Health-AARP Diet and Health Study (NIH-AARP).

Methods

Neighborhoods were classified into five groups based on economic change patterns from 2000 to 2016 using American Community Survey data: Stability, Growth, Displacement, Abandonment, and Poverty Concentration. Mortality …

Characteristics And Effectiveness Of Maternal Health Interventions To Prevent Mother-To-Child Transmission (Pmtct) Of Syphilis In A Global Setting: A Scoping Review Using Intervention Mapping As A Framework, Jinni Tang, Anusha Sajja, Christine Markham, Emily T Hebert, Irene Stafford, Sheryl Dacso, Melissa F Peskin

Faculty, Staff and Student Publications

Background: Despite the availability of cost-effective treatments, maternal syphilis continues to contribute significantly to preventable stillbirths and congenital syphilis cases worldwide. This scoping review aimed to identify and characterize maternal health interventions designed to prevent mother-to-child transmission (PMTCT) of syphilis globally, using a modified Intervention Mapping (IM) framework.

Methods: We conducted a scoping review of maternal health interventions targeting PMTCT of syphilis published between January 2010 and August 2023. Searches were performed in PubMed, Medline Ovid, and Embase, supplemented by manual reference screening. Eligible studies described at least one maternal health intervention addressing syphilis PMTCT and were analyzed using a …

Identification Of Cadm1 As An Immunotherapeutic Target And Evaluation Of A Novel Cadm1-Targeting Antibody-Drug Conjugate In Preclinical Osteosarcoma Models, Yifei Wang, Zhongting Zhang, Caterina Longo, Wendong Zhang, Qi Wang, Amer Najjar, Xiangjun Tian, Rossana N Lazcano Segura, Michael E Roth, Jonathan Gill, Douglas J Harrison, Zhaohui Xu, Yanhua Yi, Xin Zhou, Sylvester Jusu, Timothy M Stearns, Steven B Neuhauser, Carol J Bult, Jing Wang, Alexander J Lazar, Richard Gorlick

Faculty, Staff and Student Publications

Due to the paucity of validated cell surface osteosarcoma-specific targets, patients with this condition have long been excluded from the benefits of antibody-drug conjugate (ADC) therapy observed in patients with several solid and hematologic malignancies. Our comprehensive surfaceome profiling approach previously identified osteosarcoma-specific cell-surface antigens that are highly expressed in osteosarcomas but minimally expressed in normal tissues. As a result, one such antigen, CADM1, was selected for the generation of an ADC. We tested a CADM1-targeting ADC with a tesirine payload (SG3249) in vitro in osteosarcoma, rhabdomyosarcoma, and neuroblastoma patient-derived xenograft cell lines. In vivo, we tested six CADM1-expressing osteosarcoma …

Secure Distributed Multiple Imputation Enables Missing Data Inference For Private Data Proprietors, Haris Smajlović, Yi Lian, Qi Long, Ibrahim Numanagić, Xiaoqian Jiang

Faculty, Staff and Student Publications

Scattered between many healthcare providers across the US, Electronic Health Records (EHR) are extensively used for research purposes. Collaboration and sharing of EHRs between multiple institutions often provide access to more diverse datasets and a chance to conduct comprehensive studies. However, these collaboration efforts are usually hindered by privacy issues that render the pooling of such data at a centralized database impossible. Furthermore, EHRs are often incomplete and require statistical imputation prior to the study. To enable collaborative studies on top of incomplete, private EHRs, here we provide a provably secure solution built with secure multiparty computation (SMC) that provides …

Grief, Memory, And Hope: Significance Of Ancestral Land In Psalm 137, “By The Rivers Of Babylon,” In Healing Intergenerational Migration Trauma, Shimbo Pastory William

Loyola Papers

Psalm 137 presents a paradigmatic expression of exile and lament, and the power of shared hope to return to the ancestral land. Memories trigger strong feelings and a firm resolve not to “forget” the ancestral home. This paper argues from a constructive perspective that in Psalm 137, the memory of ancestral land is not merely nostalgic or a source of grief, but it functions as a theological act that preserves communal identity and sustains hope for restoration and healing. Even today, we feel strongly about land, especially ancestral lands, because they are closely connected to our identity, cherished memories, grief, …

Il-18 Metabolically Reprograms Car-Expressing Natural Killer T Cells And Enhances Their Antitumor Activity, Gabriel A Barragán Bravo, David A De La Cerda, Elisa Landoni, Kshiti Dholakia, Piotr Humeniuk, Leidy D Caraballo Galva, Ying Wang, Gengwen Tian, Boning Yang, Linjie Guo, Michael S Wood, Xavier Rios, Xin Xu, Amy N Courtney, Erica J Di Pierro, Joan Jacob, Yi-Han Li, Akshaya Adaikkalavan, Norihiro Watanabe, Sufeng Mao, George Miles, Gianpietro Dotti, Leonid S Metelitsa

Faculty, Staff and Students Publications

Invariant natural killer T cells (NKTs) have intrinsic anti-tumor properties that make them promising candidates for chimeric antigen receptor (CAR) immunotherapies. Transgenic cytokine expression can enhance cellular therapy potency, and we hypothesized that co-expressing IL-18 alone or with IL-15 would boost CAR-NKT therapeutic potential. To test this, we generated retroviral constructs expressing IL-15 and/or IL-18 with an inducible caspase 9 safety switch and co-transduced them with a GD2-specific CAR into human NKTs. Co-expression of IL-18 or IL-15/IL-18 increased CAR-NKT cytotoxicity, proliferation, and cytokine secretion in vitro compared to IL-15 alone. IL-18 also enhanced GPC3.CAR and CD19.CAR NKT activity against hepatocellular …

Transcriptomic Signature-Guided Depletion Of Intermediate Alveolar Epithelial Cells Ameliorates Pulmonary Fibrosis In Mice, Fei Peng, Chun-Sun Jiang, Zhen Zheng, Shahram Aliyari, Dan Shan, Aaryan Sabharwal, Qinyan Yin, Shigeki Saito, Chao He, Ivan O Rosas, Joseph A Lasky, Victor J Thannickal, Yong Zhou

Faculty, Staff and Students Publications

Single-cell RNA sequencing (scRNA-seq) has identified intermediate epithelial states in pulmonary fibrosis, including KRT5-/KRT17+ aberrant basaloid cells in humans and Krt8+ alveolar differentiation intermediates (ADIs) in mice. Their functional contributions to fibrogenesis, however, remain unclear. Here, we introduce an RNA-sensing-dependent protein translation technology that enables selective targeting of Krt8+ ADI cells in vitro and in vivo. Transcriptomic analysis revealed Small Proline-Rich Protein 1 A (SPRR1A) mRNA as a shared marker of murine Krt8+ ADIs and human KRT5-/KRT17+ basaloid cells, distinguishing them from other lung cell populations. Using programmable RNA sensors, we demonstrated selective EGFP-labeling of Krt8+ ADI cells in vivo, …

Plasma Proteomics And Incident Coronary Heart Disease, Matthew P Huber, Jennifer A Brody, Colleen M Sitlani, Thomas R Austin, Usman A Tahir, Shuliang Deng, Devendra Meena, Jingsha Chen, Kunihiro Matsushita, Christie M Ballantyne, Josef Coresh, Robert E Gerszten, Russell P Tracy, Ting Ye, Bruce M Psaty, Joshua C Bis, James S Floyd

Faculty, Staff and Students Publications

Background: Systematic profiling of plasma proteins in population studies offers a complementary approach to discovery of novel risk factors and may provide new insights into the causes of coronary heart disease.

Methods: To explore relationships between the circulating proteome and coronary heart disease (CHD), we evaluated associations of 4780 plasma proteins with incident CHD in the Cardiovascular Health Study (CHS, N=2856, 575 CHD events) and replicated significant associations in the Atherosclerosis Risk in Communities Study (ARIC, N = 10456; 1375 events).

Results: We find that 11 proteins significantly associate with incident CHD after adjusting for risk factors; and eight significantly …

Fragmented Foundations: Interpreter Educator Resources And Uneven Student Preparation, Kierstin S. Muroski

Journal of Interpretation

The readiness-to-work gap among graduates of signed language interpreting programs has been widely acknowledged for decades. Efforts to address the gap have primarily focused on training methods and student performance. This paper shifts the focus to interpreter educators, examining whether the inconsistencies in their awareness and use of discipline-related books may contribute to the disparate educational outcomes of students entering the workforce. Drawing on survey data from 75 interpreter educators in the United States, this study explores demographic patterns of their book awareness and usage in teaching. Results indicate that awareness and utilization of discipline-related books to support teaching are …

Defending And Challenging American Empire: The 1927-28 University Of Oregon Forensics Program World Debate Tour And The November 25, 1927, Manila "Debate Of The Century", Trond Jacobsen, David Frank

Studies in Debate and Oratory

From October 1927 through April 1928, three Oregon debaters traveled more than 25,000 miles to seventeen countries on four continents, participating in thirty-two debates and seventy-five public speaking engagements as part of the first-ever Debate World Tour. This tour was audacious, but indicative of a remarkable history of debate at Oregon. Drawing on archival materials held by the Special Collections and University Archive at the University of Oregon and other primary and contemporary materials, we document that world tour and feature a November 25, 1927, debate on Filipino independence at the Manila Opera House and the tour of America by …

The Archon, 1952 Edition, Zeta Phi Beta Sorority Incorporated

Josie Green Washington Papers

A 1952 edition pamphlet called The Archon, an official organ of the Zeta Phi Beta Sorority.

The Archon, 1951 Edition, Zeta Phi Beta Sorority Incorporated

Josie Green Washington Papers

A 1951 edition pamphlet called The Archon, an official organ of the Zeta Phi Beta Sorority.

To Extract Or Not To Extract: On What Basis Do We Make That Decision? (Part I), Ib Leth Nielsen

Taiwanese Journal of Orthodontics

The decision to remove permanent teeth is often challenging for the orthodontist, and multiple factors should be considered. The primary reason for extracting teeth is crowding, followed by aesthetic concerns, particularly the risk of creating a flat facial profile from over-retracting the front teeth. Often, the facial growth patterns are overlooked in this decision-making process. This review will explore how facial morphology, growth patterns, and maturation stages influence the extraction decision. We shall address common concerns related to extractions, such as the impact on esthetics, airways, the effect of extractions on buccal corridors, their relationship to TMJ issues, and the …

Synthesis And Characterization Of Mn4S4:Ni2S2 Chalcogenide Electrodes For Superior Supercapacitive Properties, Yasser T. Alharbi

University of Bisha Journal for Basic and Applied Sciences

The growing interest of researchers is shifted towards energy storage systems and the production of energy storage materials. In present research, an innovative Mn₄S₄:Ni₂S₂ semiconducting nanocomposite has synthesized using single source technique by fabricating di hexyldithiocarbamate ligand to further improve the efficiency of charge storing batteries. The fabricated material shown efficient optical property with direct band gap in range of 3.2–3.26eV. The crystallographic analysis examined the average crystalline size of the prepared nanocomposite particles of about 22 nm. The IR spectroscopy analysis has shown the presence of metal-sulfur bond and their peaks has …

Assessing Knowledge, Attitude, And Practice Of Diabetic Retinopathy Management Among Patients In Riyadh, Ferial M Zeried, Lulwah Mesfer Al-Haqbani, Anayochukwu Edward Anyasodor, Ezinne Ngozika, Uchechukwu L Osuagwu

University of Bisha Journal for Basic and Applied Sciences

Aim: Diabetic retinopathy (DR) is a common microvascular complication of diabetes and a leading cause of preventable vision loss. Understanding patients’ knowledge, attitudes, and practices (KAP) toward DR screening and management is critical for designing effective interventions. This study aimed to assess the KAP of individuals with diabetes regarding DR in Riyadh, Saudi Arabia.

Methods: A web-based cross-sectional survey was conducted among 535 Saudi adults with diabetes between January and April 2021. Descriptive statistics were used to summarize participant characteristics and KAP levels. Multivariate logistic regression (MLR) was performed to identify sociodemographic and clinical predictors of high KAP, with adjusted …

Prognostic Value Of Baseline Qfr In Single-Vessel Intermediate Coronary Stenosis, Yanfeng Lu, Abdulrahman Alqazzaz, Jasmine Bao, Gary S. Mintz, Jiahao Feng, Yong Zhang, Shanshan Gao, Qiang Song, Feifei Ning, Xin Huang, Ning Guo

Student Papers, Posters & Projects

BACKGROUND AND OBJECTIVES: The prognostic value of baseline Quantitative Flow Ratio (QFR) in real-world patients remains unclear. This study aimed to evaluate the prognostic value of baseline QFR and its three-tier model-low, grey-zone, and high QFR-in patients with single-vessel intermediate stenosis.

METHODS: This retrospective study included 478 patients with QFR between 0.70 and 0.90 who underwent coronary angiography between May and June 2023. Patients were stratified into Low (0.70-0.74), Grey-Zone (0.75-0.85), and High (0.86-0.90) QFR groups. The primary endpoint was major adverse cardiac events (MACE); the key secondary endpoint was target vessel failure (TVF). Kaplan-Meier and Cox proportional hazards models …