Modulation Of Corneal Sensory Processing And Pain Responses By Dry Eye And Corneal Wounding, Ebru Yaman, Yangluowa Qu, Kaylin C Arpaia, Fairouz Elsaeidi, Uma Lakshmi Balakrishnan, Lance He, Henry Skrehot, Jehan Alam, Rui Chen, Mary Ann Stepp, Cintia S De Paiva, Stephen C Pflugfelder

Faculty, Staff and Students Publications

Background: Dry eye disease (DED) is a multifactorial disorder of the ocular surface in which tear film instability, epithelial barrier disruption, and neurosensory dysfunction contribute to symptom generation. Although several contributing factors have been identified, how different forms of ocular surface stress affect sensory pathways and behavioral responses remains unclear.

Purpose: This study aimed to evaluate corneal barrier function, sensory responses, and pain-related behaviors across acute and chronic dry eye and corneal injury models, and to assess stimulus-specific responses associated with TRPV1 and TRPM8 mediated pathways.

Methods: Female C57BL/6 J wild type and Mmp9KO mice were evaluated in acute desiccating …

Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso

Faculty, Staff and Students Publications

Wastewater-based epidemiology (WBE) is the analysis of wastewater to detect pathogen levels or activity for public health awareness or action. Pioneered in the 1940s, WBE underwent a resurgence during the COVID-19 pandemic, providing important information about number of cases, outbreaks, and seasonal impact. With advancements in detection technologies and growing interest in environmental surveillance, WBE is poised to become a standard practice in public health monitoring. Here, we provide an overview of the current state of the art of pathogen WBE, including methods of molecular detection, analysis of wastewater data, real-world applications and programs, public health interventions, and benefits and …

Correction: Establishing Standardized Transthoracic Echocardiography Reference Ranges For Mouse Models: Insights Into The Impact Of Anesthesia, Sex, And Age, Manuela A Oestereicher, Christopher S Ward, Elida Schneltzer, Susan Marschall, Helmut Fuchs, Valerie Gailus-Durner, Ghina Bou About, Mohammed Selloum, Hamid Meziane, Michelle Stewart, Lydia Teboul, Clare Norris, Dale Pimm, Marina Kan, Federico López Gómez, Robert Wilson, Mayra Monroy, Sheraz Pasha, Eva Zabrodska, Jan Prochazka, David Pajuelo Reguera, Zuzana Nichtova, Yann Herault, Sara Wells, Helen Parkinson, Jason D Heaney, Radislav Sedlacek, Xiang Gao, Martin Hrabe De Angelis, Nadine Spielmann

Faculty, Staff and Students Publications

This corrects the article "Establishing standardized transthoracic echocardiography reference ranges for mouse models: insights into the impact of anesthesia, sex, and age" in volume 12, 1695034.

Molecular Heterogeneity Of Hpv-Associated Cancers And Strategies To Overcome Treatment Resistance, Sara Rasouli, Weiyi Gong, Raegan Wood, Danyal Daneshdoust, Anam Khan, Rani Mahyoob, Chongwen Cao, Zihao Yu, Nagireddy Putluri, Gennady Shvets, Haichang Li, Bo Zhao, Xuefeng Liu, Jenny Li

Faculty, Staff and Students Publications

Human papillomavirus (HPV) is a major driver of global cancer incidence, responsible for nearly all cervical cancers and a significant proportion of oropharyngeal, anal, and other anogenital cancers. Despite the availability of effective vaccines, HPV-associated cancers persist due to persistent infection, immune evasion, and the virus's ability to integrate into the host genome, contributing to molecular heterogeneity and therapeutic resistance. Here, we summarize molecular heterogeneity and the emerging combined therapeutic strategies. High-risk HPV types, notably HPV16 and HPV18, initiate carcinogenesis through persistent infection of epithelial basal cells and through the actions of the E6 and E7 oncoproteins, which disrupt the …

Once-Weekly Navepegritide In Children With Achondroplasia: The Approach Randomized Clinical Trial, Ravi Savarirayan, Ciara Mcdonnell, Carlos A Bacino, Daniel G Hoernschemeyer, Janet M Legare, M Jennifer Abuzzahab, Paul L Hofman, Philippe M Campeau, Josep Maria De Bergua Domingo, Leanne M Ward, Kevin Smit, Alden Smith, Meng Mao, Michael S Ominsky, Lærke C Freiberg, Aimee D Shu, Hanne B Hove

Faculty, Staff and Students Publications

Importance: Historically considered a skeletal dysplasia characterized by disproportionate short stature, achondroplasia is a condition with multisystemic effects due to the widespread expression of the fibroblast growth factor receptor 3 variant throughout the body, impacting muscle, neurological function, cardiorespiratory health, and health-related quality of life.

Objective: To evaluate the efficacy, safety, and tolerability of once-weekly navepegritide, an investigational prodrug of C-type natriuretic peptide, while assessing benefits beyond growth that may have important implications for complications and health-related quality of life in children with achondroplasia.

Design, setting, and participants: Enrollment for this pivotal phase 2b, randomized, double-blind, placebo-controlled trial (APPROACH) was …

The Words Community Dwelling, Spanish-Preferring Mexican/Mexican American Adults Use To Talk About Alzheimer’S Disease And Genetic Testing: Implications For Education And Outreach, Jamie C Fong, Fatima I Chavez, Karla Silos, Mirna L Arroyo-Miranda, Gabriela Castro Castro, Mark E Kunik, Joshua M Shulman, Luis D Medina

Faculty, Staff and Students Publications

Introduction: Hispanic/Latino (H/L) adults are more likely than non-Hispanic White individuals to have Alzheimer's disease (AD), yet fewer than one in five H/L adults has apolipoprotein E (APOE) Ɛ4, underscoring gaps in understanding genetic risk across H/L heritage groups. H/L adults remain underrepresented in AD research that uses genetic data for participant stratification. To inform culturally appropriate educational materials for 16 million U.S. Spanish speakers, we identified culturally salient words Spanish-preferring H/L adults use to describe AD and genetic testing beyond APOE.

Methods: Community-residing, Spanish-preferring Mexican/Mexican American adults (n = 14) completed freelisting interviews, a method eliciting …

Finding Value In Professional Learning: Developing Teacher Learning That Is Internalized And Implemented In Practice, Stephanie Dossett

Electronic Theses and Dissertations

Abstract

This study was designed after the researcher engaged in multiple mandated professional learning experiences with faculty members who expressed dissatisfaction with their learning experiences, did not desire to engage in learning on the mandated topics, and wanted to engage in different types of learning opportunities. The problem was centered around dissatisfaction with professional learning among teachers and the lack of implementation of their professional learning in the classroom. The goal was to gather feedback that could help leaders design mandated learning for teachers that they would find satisfaction in and implement in their classroom. The study used semistructured qualitative …

Faculty Perceptions Of Engaging Generation Z Students Through Positive Education In The Classroom, Ashley D. Ragsdale

Electronic Theses and Dissertations

This qualitative study examined the engagement gap between Generation Z students and faculty in higher education, emphasizing how positive education approaches can help faculty become more confident and effective instructors. Generation Z students prefer instant internet access and digital learning, have shorter attention spans, and tend to be disengaged when instructors rely on traditional teaching methods. After the COVID-19 pandemic, this engagement gap became more evident. This basic qualitative study used semistructured interviews, reflexive journaling, and nonparticipatory observations. Participants included full-time health science faculty at a private university in central Texas. Each had at least 2 years of teaching experience …

Annual Faculty Senate Meeting Minutes October 2025-June 2026, Portland State University Faculty Senate

Annual Compilations of the Faculty Senate Minutes (Minutes Only)

Meeting minutes and summaries of Faculty Senate actions for the academic year 2025-26.

Faculty Senate Monthly Packet May 2026, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The May 2026 monthly packet includes the agenda, appendices, and the Faculty Senate minutes and attachments given in the meeting held May 4, 2026.

Faculty Senate Monthly Packet March 2026, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The March 2026 monthly packet includes the agenda, appendices, and the Faculty Senate minutes and attachments given in the meeting held March 2, 2026.

Faculty Senate Monthly Packet February 2026, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The February 2026 monthly packet includes the agenda, appendices, and the Faculty Senate minutes and attachments given in the meeting held February 2, 2026.

Faculty Senate Monthly Packet January 2026, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The January 2026 monthly packet includes the agenda, appendices, and the Faculty Senate minutes and attachments given in the meeting held January 5, 2026.

Does It Matter What People Lie About?, Stefanie Jung, Peter Krebs, Monika Leszczynska

Faculty Scholarship

We investigate whether people’s moral judgments of lies in pre-contractual negotiations differ from their views on whether such lies should give the deceived party a legal right to rescind the contract, and whether these judgments depend on the content of the lie. In a vignette study with 832 German students and 885 participants from Germany, Italy, and the United States, respondents evaluated a range of common negotiation lies. Across samples, participants were generally more likely to deem a lie immoral than to believe it should justify rescission, but the size of this gap varied depending on the lie’s subject. Lies …

Information Law Pluralism, Hannah Bloch-Wehba

Faculty Scholarship

Information-intensive activities are reshaping political, social, and economic institutions. As they respond to these shifts, legislators and regulators are embracing information as a regulatory device for tech. Far from limiting themselves to public disclosure, consumer notice, and other traditional mechanisms of fostering transparency and information flows, however, legislators are using other, more nuanced tools to incentivize regulated entities to obtain, generate, and share information.

This Article maps the landscape of the emerging information-based regimes for regulating tech and assesses their conceptual and practical implications. It canvasses an extensive set of recently enacted laws regulating the information economy and shows that, …

Moral Progress In Legal Doctrine, Philip Petrov

Faculty Scholarship

This article integrates the concept of moral progress – here, moral improvement in the thinking and behavior of individuals over time – into the study of legal doctrine. The article first presents a naturalistic account of what moral progress is and describes three of its most historically and analytically important forms: (1) moral circle expansion, (2) moral domain expansion, and (3) increasing sensitivity to proportionality. The article then analyzes three historical developments in U.S. tort law that qualify as instances of moral progress: (1) the partial demise of the “suicide rule” beginning around the 1980s (according to …

Evaluating Llms For Cpe Identification In Iot Reconnaissance, Christopher Davisson

EWU Masters Thesis Collection

Vulnerability identification during penetration testing relies on rigid string-matching to map network scan data to Common Platform Enumeration (CPE) identifiers and downstream Common Vulnerabilities and Exposures (CVEs). The approach frequently fails on physical Internet of Things (IoT) devices, which produce non-standard, irregular service banners that resist deterministic parsing. Large Language Models can reason through these fuzzy associations, but cloud-hosted models introduce cost, latency, and operational security concerns when processing reconnaissance data from live networks. This thesis asks whether locally-hosted open-weight Large Language Models (LLMs) can perform this task well enough to be useful, and how performance varies with model scale, …

Handwriting Recognition In Vr, Dominique Mosley

EWU Masters Thesis Collection

Virtual Reality (VR) is slowly becoming more popular for more than just entertainment. VR can be found in educational, office, and even healthcare settings to help discover more intuitive ways to teach, collaborate, and treat patients. Outside of the virtual world, these environments typically rely on writing for communicating or note-taking. Currently, VR input forces users to rely on clunky on-screen keyboards which disrupts the user’s immersion and breaks the flow of natural interaction. This thesis explores the potential of VR as a learning platform by combining it with artificial intelligence (AI). It aims to develop a VR-enhanced handwriting practicing …

Dietary Ecology Of Waterfowl Nest Predators In The Prairie Pothole Region: Evaluating Resource Use From Species To Individual Using Stable Isotope Analysis, Grace Barthelmess

EWU Masters Thesis Collection

Nest predation is a primary factor influencing waterfowl productivity in the Prairie Pothole Region (PPR) of North America. Although this system is intensely managed and studied, research has largely focused on how predators affect waterfowl populations, with comparatively little attention to how predators actually rely on waterfowl as a resource. Understanding predator feeding ecology is therefore critical for informing effective management strategies and interpreting the complexity of predator-prey interactions on this landscape. My objective overall was to elucidate the feeding ecology of nine focal predator species commonly associated with waterfowl nest predation in the Aspen Parkland Ecoregion of the PPR: …

Assessing Forest Health And Small Mammals After A Limited Suppression Wildfire In Colville National Forest, Samantha J. Kennel

EWU Masters Thesis Collection

In the face of a wildfire crisis, there is a growing need to expand the pace and scale of forest treatments, including the strategic use of wildfire as a management tool. However, ecological outcomes remain uncertain in forests shaped by more than a century of fire suppression. The 2022 Thor Fire, a managed wildfire in the Colville National Forest, Washington, provides an opportunity to evaluate forest health in a relatively understudied system. Using a control–impact design, I established 100 monitoring plots in burned and adjacent unburned forests to assess how wildfire and fire severity influence forest structure, fuels, and tree …

Religious Freedom, Jesuit Mission, And Dei, William M. Treanor, Amelia J. Uelmen

Georgetown Law Faculty Publications and Other Works

The ability of Jesuit educational institutions to pursue a central part of their mission – that of fostering diverse, equitable and inclusive educational environments – is under attack. This essay outlines several dimensions of their religiously-grounded mission and the reasons to strongly protect from government interference the rights of Jesuit universities to implement programs and practices that align with DEI values. First, for Jesuit universities, these programs and practices are rooted in a much deeper culture of the more than 2,000-year old Catholic intellectual tradition and the now 500-year old tradition of Jesuit spirituality. Second, drawing on the classic work …

Predictive Protest Policing, Christian Powell Sundquist

SMU Law Review

The policing of dissent in America is undergoing a radical transformation that threatens the fundamental right to protest. Demonstrations are no longer merely surveilled; they are algorithmically suppressed. Law enforcement agencies increasingly deploy algorithmic social media surveillance to predict protest violence, forecasting potential “riots” and justifying militarized responses before a single demonstrator takes to the street. This Article identifies and challenges what it terms “predictive protest policing,” arguing that these systems do not objectively detect threats but actively construct them, disproportionately targeting racial justice demonstrations. Drawing on evidence from the federal response to immigration protests in Minneapolis, the preemptive policing …

Improving Staff Knowledge And Consistency In Sat And Sbt Practices In The Critical Care Unit: A Quality Improvement Initiative, Morgan Crapo

Master's Theses and Capstones

Abstract

Background: Spontaneous Awakening Trails (SATs) and Spontaneous Breathing Trials (SBTs) are key components of the ICU Liberation Bundle and have been associated with shorter durations of mechanical ventilation, reduced intensive care unit (ICU) length of stay (LOS), and improvement in patient outcomes. Despite having strong evidence supporting their use, implementation remains inconsistent due to knowledge gaps, workflow barriers and interdisciplinary communication challenges.

Local Problem: This quality improvement (QI) project aimed to improve critical care nurses’ knowledge and confidence regarding the implementation of SATs and SBTs through an evidence-based educational intervention.

Methods: Guided by the Plan-Do-Study-Act (PDSA) framework, this QI …

A Quality Improvement Project: Enhancing Nursing Knowledge And Patient Safety In The Prevention Of Hospital-Acquired Pressure Injuries (Hapis) In A Medical-Surgical Unit, Kristen Vartabedian

Master's Theses and Capstones

Background: Hospital-acquired pressure injuries (HAPIs) are a significant quality indicator within the hospital system. HAPIs increase hospitalization, morbidity, and associated healthcare costs. The current evidence suggests that ongoing nursing education can improve pressure injury prevention and help in the early identification.

Local Problem: Nurses within a medical-surgical unit demonstrated a gap in knowledge in the identification of hospital acquired pressure injuries and lack of accuracy when charting skin findings. Thus, contributing to a delay in recognition and treatment of HAPIs.

Methods: This quality improvement project utilized the Plan-Do-Study-Act (PDSA) framework to guide implementation of educational flipbooks. Materials contained standardized wound …

Implementing A Nurse Re-Education Program To Promote Timely Use Of The Jada® System In The Postpartum Hemorrhage Cascade: A Quality Improvement Project, Maegan E. Doody

Master's Theses and Capstones

Background: Postpartum hemorrhage (PPH), defined as blood loss greater than 1,000 mL after delivery, is a leading cause of maternal morbidity in the United States. Identification of risk factors and timely intervention are critical to improving maternal outcomes after delivery. First-line interventions include manual uterine massage, uterotonic medications, and antifibrinolytic medications; however, when bleeding is not well controlled, the Jada® System (Jada) is a newer vacuum-induced hemorrhage control device with a high efficacy and safety profile, particularly when implemented earlier in the hemorrhage cascade.

Local Problem: In 2025, the annual rate of PPH within the microsystem was 7.29%, …

Reducing Readmissions For Copd Through Improved Education: A Gap Analysis, Raphael Gaughan

Master's Theses and Capstones

No abstract provided.

Promoting Equitable Access To Postpartum Hemorrhage Education: A Quality Improvement Project Using Educational Interventions For Night Shift Nurses, Michelle Stella

Master's Theses and Capstones

Abstract

Background: Postpartum hemorrhage (PPH) is a serious condition that can lead to maternal morbidity or mortality following the birth of their child. It is important for nurses to be properly educated to manage this condition quickly and efficiently. Night shift nurses often face barriers to accessing educational opportunities during their shift because most education is tailored to daytime hours.

Local Problem: At the project site facility, night shift nurses perceived inconsistent access to education compared to day shift nurses. This gap highlighted the need for more flexible educational modalities to meet the needs of night shift nurses.

Methods: This …

Addressing Perception Of Nurse Burnout Through Educational Interventions On An Inpatient Hematology And Oncology Unit: A Quality Improvement Project, Kendra Flint

Master's Theses and Capstones

Introduction Nurse burnout is a growing concern in healthcare due to its negative effects on nurse well-being, staff retention, patient safety and quality of care. This quality improvement project evaluated whether a brief educational intervention could improve nurses’ confidence in recognizing and managing early signs of burnout within an inpatient hematology and oncology unit.

Methods This QI project utilized the Plan-Do-Study-Act (PDSA) framework to guide implementation and evaluation. Registered nurses completed anonymous pre- and post- intervention electronic surveys and descriptive statistics were used to compare change in self-reported confidence and burnout perception.

Intervention Participants were directed through a brief electronic …

Improving Efficiency In The Intensive Care Unit Through Reduction Of Nurse Burnout: A Quality Improvement Initiative, Johanna Grace Koroma

Master's Theses and Capstones

Abstract

Background: Intensive care unit (ICU) nursing is prone to high levels of burnout, which poses concern for staff wellbeing, patient safety, and microsystem strain (Kerlin et al., 2020). Educational interventions may serve as a means of increasing awareness on the issue and reducing the effects of burnout, through promotion of evidence-based management strategies.

Local Problem: One ICU microsystem identified several key contributing factors to nurse burnout, including staffing shortages, limited resources, competing responsibilities within the macrosystem, and insufficient organizational support (Zhang et al., 2025). Baseline survey data of the population observed a prevalence of 50% “high” burnout profiles among …

Increasing Nursing Perceptions On Advanced Directives Through Education To Promote Patient Centered Care, Michelle Strong

Master's Theses and Capstones

No abstract provided.