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2026

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An Educational Intervention On Mutual Goal Setting For Hospital Nurses: A Mixed-Methods Study, Teresa Jerofke-Owen, Kristi Opper, Joseph Beiler, Maharaj Singh Jan 2026

An Educational Intervention On Mutual Goal Setting For Hospital Nurses: A Mixed-Methods Study, Teresa Jerofke-Owen, Kristi Opper, Joseph Beiler, Maharaj Singh

College of Nursing Faculty Research and Publications

Background:

Including patients in mutual goal setting is one mechanism to personalize care delivery and improve patient outcomes.

Objective:

The purpose of this study was to examine the impact of a nurse educational intervention about mutual goal setting on nurse engagement and self-efficacy for goal setting and the nurse/patient experience of goal setting.

Methods:

During this explanatory, sequential mixed-methods study, nurse engagement in goal setting and goal quality was assessed through chart audits 1-month pre-intervention (n = 173) and 1 and 3-months (n = 144, n = 137) post-intervention. Nurse self-efficacy was measured with the Appraisal Inventory Tool. Patient experience …


In Search Of The Soul Of Creativity: Authorship, Agency, And Meaning In Refractive Collaboration With Generative Ai, Fatima Nazir Jan 2026

In Search Of The Soul Of Creativity: Authorship, Agency, And Meaning In Refractive Collaboration With Generative Ai, Fatima Nazir

Theses and Dissertations

When images can be generated in seconds, what remains uniquely human in the act of creation? In Search of the Soul of Creativity: Authorship, Agency, and Meaning in Refractive Collaboration with Generative AI investigates where authorship, agency, and meaning reside within design practices mediated by generative AI. Rather than using AI to produce predictable results, this research deliberately relinquishes control to observe how generative systems interpret language through their own learned associations. Through a practice-led investigation across four generative models within the Higgsfield platform, user prompts were progressively shortened from full sentences to single words, revealing recurring patterns and cultural …


A Novel Superaug Adaptive Data Augmentation Strategy For Metabolic Syndrome Prediction: The First Egyptian National Cohort Study With Multi-National Comparison, Nihal Elsonny, Ashraf Elsharkawy, Abeer Tawakol, Amira Y. Haikal Jan 2026

A Novel Superaug Adaptive Data Augmentation Strategy For Metabolic Syndrome Prediction: The First Egyptian National Cohort Study With Multi-National Comparison, Nihal Elsonny, Ashraf Elsharkawy, Abeer Tawakol, Amira Y. Haikal

Mansoura Engineering Journal

Metabolic Syndrome (MetS) is a multifactorial disorder associated with an increased risk of cardiovascular disease, type 2 diabetes, and obesity-related complications. Early and accurate prediction of MetS remains challenging due to heterogeneous data sources, class imbalance, limited sample sizes in regional studies, and poor generalization across populations.

This study introduces a comprehensive machine learning framework for predicting MetS and its prognostic factors using two heterogeneous datasets: a newly collected Egyptian clinical cohort and the U.S.-based (NHANES) [CDC, 2023] dataset. For each dataset, multiple experimental pipelines are developed, integrating preprocessing, feature selection, data augmentation, hyperparameter tuning, and ensemble modeling. …


Intelligent Torque Control Of Switched Reluctance Motors Based On Ditc And Wavelet Neural Network, Ameer L. Saleh, László Számel Jan 2026

Intelligent Torque Control Of Switched Reluctance Motors Based On Ditc And Wavelet Neural Network, Ameer L. Saleh, László Számel

Mansoura Engineering Journal

Switched Reluctance Motors (SRMs) have been considered a high-performance and environmentally friendly solution for Electric Vehicle (EV) applications owing to their simpler construction, robust design, and high efficiency. However, it suffers from high torque ripple and acoustic noise due to its highly nonlinear magnetic characteristics and double-salient structure.  This paper introduces a nonlinear torque control based on the Direct Instantaneous Torque Control (DITC) scheme and a Wavelet Neural Network (WNN)  to achieve better dynamic response and mitigate torque ripple.  The proposed WNN is employed as a nonlinear torque controller, inserted between the torque error and the hysteresis torque controller within …


State-Dependent Queueing For Adaptive Signal Control: A Simulation-Based Performance Evaluation, Shaimaa Alseddiek, Usama Elrawy Shahdah, Hala B. Nafea, Hossam El-Din Moustafa, El-Said Ahmed Marzouk, Mohamed M. Ashour Jan 2026

State-Dependent Queueing For Adaptive Signal Control: A Simulation-Based Performance Evaluation, Shaimaa Alseddiek, Usama Elrawy Shahdah, Hala B. Nafea, Hossam El-Din Moustafa, El-Said Ahmed Marzouk, Mohamed M. Ashour

Mansoura Engineering Journal

Urban traffic congestion persists as a critical challenge to transportation system efficiency, sustainability, and safety. Traditional queuing models utilizing fixed service rates inadequately represent the dynamic feedback between congestion and capacity in real vehicular flow. State-Dependent Queuing Models (SDQMs) address this limitation by modelling service rate as a function of queue length or density. This research advances SDQM application for adaptive traffic signal control through development of a calibrated state-dependent departure rate implemented within a microscopic simulation environment using SUMO and TraCI. Six control strategies including fixed-time, actuated, and two SDQM variants were evaluated across traffic demands ranging from undersaturated …


Psychological Impact Of Cultural Heritage Vr Experience Using Well-Mind Framework. (Case Study: Mahmoud Sami Palace In Mansoura)., Sara Ahmed El-Bayoumi, Hager Ahmed El-Sayed El-Ayouti, Mohamed Mohamed Shawki Abo Leila Jan 2026

Psychological Impact Of Cultural Heritage Vr Experience Using Well-Mind Framework. (Case Study: Mahmoud Sami Palace In Mansoura)., Sara Ahmed El-Bayoumi, Hager Ahmed El-Sayed El-Ayouti, Mohamed Mohamed Shawki Abo Leila

Mansoura Engineering Journal

This study examines the psychological effects of immersive virtual reality (VR) experiences designed to preserve and disseminate intangible cultural heritage. It addresses the growing challenge of declining cultural engagement and the need for innovative tools that support psychological well-being, emotional engagement, and cultural connection. A VR-based reconstruction was developed within the historic Mahmoud Sami Al-Baroudi Palace in Mansoura, Egypt, focusing on traditional Egyptian practices and oral storytelling. The evaluation employed the WELL-MIND framework alongside participant feedback to assess both structured well-being indicators and subjective user experiences. The WELL-MIND-based assessment indicated improvements in cognitive stimulation, emotional engagement, and environmental perception. In …


Construction-Phase Leed Compliance In Egypt: Development Of A Rule-Based Expert System For Contractor Decision Support, Mohamed R. Ahmed, Atef A. Ragab, Sameh Y. Mahfouz Jan 2026

Construction-Phase Leed Compliance In Egypt: Development Of A Rule-Based Expert System For Contractor Decision Support, Mohamed R. Ahmed, Atef A. Ragab, Sameh Y. Mahfouz

Mansoura Engineering Journal

This study develops a rule-based expert system implemented in Python to support contractors in achieving LEED BD+C: New Construction v4 certification during the construction phase in Egypt. The research identifies and validates construction-phase obstacles affecting LEED compliance through a structured questionnaire targeting building contractors in Egypt. The questionnaire process was conducted in two stages: a pilot survey was used to screen and refine the initially identified obstacles, while the main survey was used to validate the practical relevance of the retained obstacles within the Egyptian construction context. In parallel, the study analyzes construction-phase prerequisites and credits relevant to contractors through …


Experimental Investigation And Optimization Of Process Parameters Affecting The Compressive And Flexural Strength Of Epoxy Concrete For Machine Tool Structure By Using Taguchi Method, Amitkumar C Gohil, Hardik G. Chothani Jan 2026

Experimental Investigation And Optimization Of Process Parameters Affecting The Compressive And Flexural Strength Of Epoxy Concrete For Machine Tool Structure By Using Taguchi Method, Amitkumar C Gohil, Hardik G. Chothani

Mansoura Engineering Journal

The structural performance of machine tool is strongly influenced by rigidity and damping characteristic; however, conventional material such as grey cast iron and steel exhibits limitation in achieving an optimal balance between weight, strength and vibration damping. The necessitates the development of alternative material with improved performance. In this study epoxy concrete is investigated as a potential material for machine tool structure, focusing on its compressive strength and flexural strength. A systematic experimental approach based on Taguchi method (L25 orthogonal array) was employed to optimize key process parameter, including resin contain, aggregate size, sand proportion, shaking time and curing duration. …


Professional Quality Of Life Among Medical Surgical And Telemetry Registered Nurses, William Lim, Emy-Lee Marie Anglo Ricafrente, Jenny Carrillo Jan 2026

Professional Quality Of Life Among Medical Surgical And Telemetry Registered Nurses, William Lim, Emy-Lee Marie Anglo Ricafrente, Jenny Carrillo

Publications 2026-present

No abstract provided.


Exploring Shared Experiences As Citizen Sport Diplomats: A Collaborative Self-Ethnography, Randall J. Griffiths, Jacob K. Tingle, Angela Breidenstein Jan 2026

Exploring Shared Experiences As Citizen Sport Diplomats: A Collaborative Self-Ethnography, Randall J. Griffiths, Jacob K. Tingle, Angela Breidenstein

School of Business Faculty Research

Research purpose: This study was a critical analysis of the lived experiences of three American university professors who served as volunteer citizen diplomats in a bi-lateral U.S. State Department sport exchange program with North Macedonian volleyball coaches.

Research methods: With the aim of capturing the experience of serving as citizen sport diplomats and making sense of it to inform future practice, this research utilized a collaborative self-ethnography approach. This reflexive approach brings together: (a) analytic autoethnography as individuals themselves are engaged in the ethnography and study, and (b) collective ethnography as a team collects and makes sense of shared data …


Two-Pyramids Model Of Radicalization To Terrorism, Clark Mccauley, Sophia Moskalenko Jan 2026

Two-Pyramids Model Of Radicalization To Terrorism, Clark Mccauley, Sophia Moskalenko

Psychology Faculty Research and Scholarship

This chapter reviews the origins and developments of the Two-Pyramids Model of radicalization, which distinguishes between the radicalization of opinions and the radicalization of actions. The Radicalization of Action Pyramid categorizes individuals from passive (inert) to those committing terrorist acts, while the Radicalization of Opinion Pyramid progresses from neutrality to a personal moral obligation to act violently for a cause. Empirical studies, including the Activism and Radicalism Intention Scales (ARIS), support the model’s distinction between activism and radicalism as separate dimensions. The chapter highlights the importance of group dynamics, diagnostic and prognostic frames, and the role of public opinion in …


Walking And Wondering, Helen T. Tran Jan 2026

Walking And Wondering, Helen T. Tran

Theses and Dissertations

My thesis approaches walking as a form of inquiry and the Flood Wall as a site open to reinterpretation. I believe that the way we walk changes the way we observe and experience the world around us. This contrast between purposeful and leisurely walking reveals how time and intention shape our awareness of space. When walking is no longer dictated by urgency, it invites observations and questions. Slowing our pace allows curiosity to emerge, which aligns with my design ethos of asking questions as a foundation for understanding and creating meaningful experiences.

The Flood Wall’s emphasis on uninterrupted movement prioritizes …


A Qualitative Analysis Of Teacher-Report Modifications Of A Tier 2 Evidence-Based Program In Elementary Schools After Implementation Supports Are Withdrawn, Navneet Kaur Jan 2026

A Qualitative Analysis Of Teacher-Report Modifications Of A Tier 2 Evidence-Based Program In Elementary Schools After Implementation Supports Are Withdrawn, Navneet Kaur

Theses and Dissertations

Growing literature emphasizes the importance of examining modifications (i.e., responses to unforeseen challenges and deliberate changes to a program) made by implementers to understand the long-term outcomes of evidence-based programs (EBPs), particularly after formal implementation supports, such as training and coaching, are withdrawn. Although prior research has documented that they occur during implementation, less is known about whether modifications occur once external supports are no longer available, and if so, what types of modifications are made, and the rationale for them. This gap is especially salient in school settings for teacher-delivered interventions. To address this gap, this study used semi-structured …


Artificial Intelligence And Mental Health: Promise, Pitfalls And Ethical Priorities, Maharaj Singh Jan 2026

Artificial Intelligence And Mental Health: Promise, Pitfalls And Ethical Priorities, Maharaj Singh

College of Nursing Faculty Research and Publications

Mental health conditions are prevalent across the lifespan, yet workforce shortages, long waiting times, and fragmented systems mean many people never receive timely, evidence‑based care. Artificial intelligence (AI), including machine‑learning classifiers and large language models (LLMs), is being explored to support earlier detection, closer symptom monitoring and scalable psychoeducation. Early studies suggest AI can surface risk signals from language, sleep/activity traces and clinical notes; summarise complex records for clinicians; and deliver structured self‑help at scale. At the same time, safety, bias, privacy and accountability concerns remain salient.


University Of New Hampshire Library Annual Report 2026: Better Together, Mairead Small Staid Jan 2026

University Of New Hampshire Library Annual Report 2026: Better Together, Mairead Small Staid

Annual Reports and Statistics

No abstract provided.


A Firm’S Operational Risk: Data Set And Empirical Evidence, Vivek Astvansh, Joseph J. Simpson Jan 2026

A Firm’S Operational Risk: Data Set And Empirical Evidence, Vivek Astvansh, Joseph J. Simpson

International Business and Entrepreneurship Faculty Publications

Problem definition: A firm’s stakeholders would benefit from a quantitative measure of the managerial disclosure of its operational risk and the implications of this disclosure. However, a quantitative and scalable measure of a firm’s disclosed operational risk is unavailable. Thus, the firm’s stakeholders remain unaware of its disclosed operational risk and the risk’s implications. Methodology/results: U.S. law requires a public firm to textually disclose its operational and nonoperational risks in Item 1A of its annual report (i.e., Form 10-K). We train 64 transformer models on U.S. public firms’ Item 1A text to score 131,920 firm-years (16,959 firms, 2005 to 2024) …


Effect Of Graphene Oxide On The Upconversion Photoluminescence Behavior Of Er/Yb Co-Doped Pvdf-Go Composite Nanofibers, Saptasree Bose, Jack Ryan Summers, Bhupendra B. Srivastava, Karen Lozano, Victoria Padilla-Gainza Jan 2026

Effect Of Graphene Oxide On The Upconversion Photoluminescence Behavior Of Er/Yb Co-Doped Pvdf-Go Composite Nanofibers, Saptasree Bose, Jack Ryan Summers, Bhupendra B. Srivastava, Karen Lozano, Victoria Padilla-Gainza

Mechanical Engineering Faculty Publications

Upconversion photoluminescence (UCPL) materials, particularly rare-earth (RE) doped nanoparticles, have garnered significant attention due to their ability to convert near-infrared (NIR) excitation into visible emission, offering benefits such as high photostability, long lifetimes, low autofluorescence, and deep tissue penetration. Among various platforms, polymer-based one-dimensional (1D) nanofibers with in-situ lanthanide doping remain relatively unexplored, despite their superior mechanical flexibility, processability, and potential for improved luminescence performance. In this study, we report the fabrication and UCPL quenching behavior of Er3+/Yb3+ co-doped polyvinylidene difluoride (PVDF) nanofibers incorporated with graphene oxide (GO), synthesized for the first time using the scalable Forcespinning® technique. PVDF, a …


Uncovering The Disciplinary Pulse Of Library And Information Science Through Large-Scale Topic Modelling Of Openalex Scholarly Literature, Sailendra Malik, Sukumar Mandal Jan 2026

Uncovering The Disciplinary Pulse Of Library And Information Science Through Large-Scale Topic Modelling Of Openalex Scholarly Literature, Sailendra Malik, Sukumar Mandal

Library Philosophy and Practice (e-journal)

Library and Information Science is among the oldest and intellectually pluralistic scholarly disciplines but the inner thematic structure has not been established. The article develops a systematic and data intensive mapping of the field by the Latent Dirichlet Allocation topic modelling to 7,824 articles in the English language indexed in OpenAlex in the year 2000 to 2025. A ten topic solution is an optimised solution that identifies a group of readable and sensible thematic domains including information literacy digital libraries scientometrics archives and scholarly communication. The analysis of temporal trajectory reveals that there have been consistent expansion at the emergent …


From Digital Skills To Digital Ventures: Exploring The Influence Of Digital Competence On Infopreneurship Intentions Of Library And Information Science Students In Nigerian Polytechnics, Uwaebuka Wisdom Madu Dr., Stephen Adekunle Ajayi Dr Jan 2026

From Digital Skills To Digital Ventures: Exploring The Influence Of Digital Competence On Infopreneurship Intentions Of Library And Information Science Students In Nigerian Polytechnics, Uwaebuka Wisdom Madu Dr., Stephen Adekunle Ajayi Dr

Library Philosophy and Practice (e-journal)

The focus of this study was to investigate the influence of digital competence on infopreneurship intention among Library and Information Science (LIS) students in federal polytechnics in South-West Nigeria, a context characterized by high graduate unemployment and rapid digital transformation. Guided by the Theory of Planned Behaviour and Eshet-Alkalai's Digital Literacy Model, a descriptive survey design was employed. The population comprised 638 final-year LIS students across four federal polytechnics, with a sample of 468 selected through multi-stage sampling. A validated questionnaire with a reliability coefficient of 0.828 was used for data collection. 388 responses amounting to 82.9% response rate was …


Dietary Ecology Of Waterfowl Nest Predators In The Prairie Pothole Region: Evaluating Resource Use From Species To Individual Using Stable Isotope Analysis, Grace Barthelmess Jan 2026

Dietary Ecology Of Waterfowl Nest Predators In The Prairie Pothole Region: Evaluating Resource Use From Species To Individual Using Stable Isotope Analysis, Grace Barthelmess

EWU Masters Thesis Collection

Nest predation is a primary factor influencing waterfowl productivity in the Prairie Pothole Region (PPR) of North America. Although this system is intensely managed and studied, research has largely focused on how predators affect waterfowl populations, with comparatively little attention to how predators actually rely on waterfowl as a resource. Understanding predator feeding ecology is therefore critical for informing effective management strategies and interpreting the complexity of predator-prey interactions on this landscape. My objective overall was to elucidate the feeding ecology of nine focal predator species commonly associated with waterfowl nest predation in the Aspen Parkland Ecoregion of the PPR: …


Relationships Between Benthic Macroinvertebrate Communities And Environmental Conditions In Headwater Tributaries Of The Pend Oreille Lake Watershed, Idaho, Devlin Mee Jan 2026

Relationships Between Benthic Macroinvertebrate Communities And Environmental Conditions In Headwater Tributaries Of The Pend Oreille Lake Watershed, Idaho, Devlin Mee

EWU Masters Thesis Collection

Benthic macroinvertebrates are widely used indicators of stream condition, and their communities respond to thermal and land-use conditions in headwater streams. This study characterized macroinvertebrate biomass, community composition, and diversity across forested headwater tributaries of the Pend Oreille lake watershed in northern Idaho, and examined their relationships with summer temperature, land development, and road proximity. Samples from thirteen streams collected in 2024 were identified to genus, measured, and converted to estimated biomass using published length–mass regressions; ten streams had recovered temperature loggers. Because environmental variables were characterized once per stream, all analyses were conducted at the stream level.

Estimated total …


Limosilactobacillus Reuteri Alleviates Proinflammatory T-Cell-Mediated Liver Injury And Transcriptomic Changes In Immunocompromised Mice, Ana Fadhel Alvarez, Zheng Yin, Beanna Okeugo, Alexander Banerjee, Meng Luo, Christopher M Taylor, Salomea Giorgberidze, Vaishali Harne, Rambabu Majji, Melissa N Munroe, Ji Ho Suh, Stephen T C Wong, Kang Ho Kim, Hari Krishna Yalamanchili, Suhair Al Salihi, Jon Marc Rhoads, Yuying Liu Jan 2026

Limosilactobacillus Reuteri Alleviates Proinflammatory T-Cell-Mediated Liver Injury And Transcriptomic Changes In Immunocompromised Mice, Ana Fadhel Alvarez, Zheng Yin, Beanna Okeugo, Alexander Banerjee, Meng Luo, Christopher M Taylor, Salomea Giorgberidze, Vaishali Harne, Rambabu Majji, Melissa N Munroe, Ji Ho Suh, Stephen T C Wong, Kang Ho Kim, Hari Krishna Yalamanchili, Suhair Al Salihi, Jon Marc Rhoads, Yuying Liu

Children’s Nutrition Research Center Staff Publications

Background: A deficiency of immunosuppressive regulatory T cells, as seen in scurfy (SF) mice or in IPEX syndrome in humans, can lead to multiorgan inflammation. Oral administration of the probiotic Limosilactobacillus reuteri Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM) 17938 prolongs survival and reduces Th1- and Th2-associated inflammation in SF mice. It remains unclear how DSM 17938-educated SF-CD4+ T cells modulate T-cell-liver communication.

Methods: To characterize CD4+ T cells from SF mice orally administered DSM 17938 (Prob-SF-CD4+ T cells) and to compare them with CD4+ T cells from SF mice (SF-CD4+ T cells), cells isolated from SF spleens were …


Mapping The Structural Connections Between The Anterior Cingulate Cortex And The Insula/Ventrolateral Prefrontal Cortex.Mapping The Structural Connections Between The Anterior Cingulate Cortex And The Insula/Ventrolateral Prefrontal Cortex, Wei Tang, Javier Guaje, Shreyas Fadnavis, Sarah R Heilbronner, Eleftherios Garyfallidis Jan 2026

Mapping The Structural Connections Between The Anterior Cingulate Cortex And The Insula/Ventrolateral Prefrontal Cortex.Mapping The Structural Connections Between The Anterior Cingulate Cortex And The Insula/Ventrolateral Prefrontal Cortex, Wei Tang, Javier Guaje, Shreyas Fadnavis, Sarah R Heilbronner, Eleftherios Garyfallidis

Faculty, Staff and Students Publications

The anterior cingulate cortex (ACC) is functionally closely related with the insula and the ventral lateral prefrontal cortex (vlPFC). The ACC and insula are the main hubs of the salience network, a set of functionally related brain regions involved in detecting salient stimuli and coordinating inter-network communication, while communication between ACC and vlPFC is closely linked to inhibitory control. However, despite strong indirect evidence from nonhuman primate (NHP) tract tracing, the structural connections between the ACC and the insula/vlPFC remain poorly understood in the human brain, in part because standard approaches fail to capture this projection. In this study, we …


Disrupted Intrathalamic And Thalamocortical Structural Covariance Networks In Posttraumatic Stress Disorder, Nick Steele, Ahmed Hussain, Delin Sun, C Lexi Baird, Courtney Russell, Neda Jahanshad, Lauren E Salminen, Miranda Olff, Jessie L Frijling, Dick J Veltman, Saskia B J Koch, Laura Nawijn, Mirjam Van Zuiden, Li Wang, Ye Zhu, Gen Li, Dan J Stein, Jonathan Ipser, Sheri Koopowitz, Yuval Neria, Xi Zhu, Orren Ravid, Sigal Zilcha-Mano, Amit Lazarov, Benjamin Suarez-Jimenez, Ashley A Huggins, Jennifer Stevens, Kerry Ressler, Tanja Jovanovic, Sanne J H Van Rooij, Negar Fani, Emily L Dennis, David F Tate, David X Cifu, William C Walker, Elisabeth A Wilde, Ivan Rektor, Pavel Říha, Milissa L Kaufman, Lauren A M Lebois, Justin T Baker, Anthony King, Israel Liberzon, Mike Angstadt, Nicholas D Davenport, Seth G Disner, Scott R Sponheim, Thomas Straube, David Hofmann, Guang Ming Lu, Rongfeng Qi, Amit Etkin, Adi Maron-Katz, Xin Wang, Austin Kunch, Hong Xie, Yann Quidé, Wissam El-Hage, Shmuel Lissek, Hannah Berg, Steven E Bruce, Josh Cisler, Marisa Ross, Ryan Herringa, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine Larson, Terri A Deroon-Cassini, Carissa W Tomas, Jacklynn M Fitzgerald, Brandee Feola, Jennifer U Blackford, Bunmi O Olatunji, Geoffrey May, Steven M Nelson, Evan M Gordon, Chadi G Abdallah, Ruth Lanius, Maria Densmore, Jean Théberge, Richard W J Neufeld, Paul M Thompson, Rajendra A Morey Jan 2026

Disrupted Intrathalamic And Thalamocortical Structural Covariance Networks In Posttraumatic Stress Disorder, Nick Steele, Ahmed Hussain, Delin Sun, C Lexi Baird, Courtney Russell, Neda Jahanshad, Lauren E Salminen, Miranda Olff, Jessie L Frijling, Dick J Veltman, Saskia B J Koch, Laura Nawijn, Mirjam Van Zuiden, Li Wang, Ye Zhu, Gen Li, Dan J Stein, Jonathan Ipser, Sheri Koopowitz, Yuval Neria, Xi Zhu, Orren Ravid, Sigal Zilcha-Mano, Amit Lazarov, Benjamin Suarez-Jimenez, Ashley A Huggins, Jennifer Stevens, Kerry Ressler, Tanja Jovanovic, Sanne J H Van Rooij, Negar Fani, Emily L Dennis, David F Tate, David X Cifu, William C Walker, Elisabeth A Wilde, Ivan Rektor, Pavel Říha, Milissa L Kaufman, Lauren A M Lebois, Justin T Baker, Anthony King, Israel Liberzon, Mike Angstadt, Nicholas D Davenport, Seth G Disner, Scott R Sponheim, Thomas Straube, David Hofmann, Guang Ming Lu, Rongfeng Qi, Amit Etkin, Adi Maron-Katz, Xin Wang, Austin Kunch, Hong Xie, Yann Quidé, Wissam El-Hage, Shmuel Lissek, Hannah Berg, Steven E Bruce, Josh Cisler, Marisa Ross, Ryan Herringa, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine Larson, Terri A Deroon-Cassini, Carissa W Tomas, Jacklynn M Fitzgerald, Brandee Feola, Jennifer U Blackford, Bunmi O Olatunji, Geoffrey May, Steven M Nelson, Evan M Gordon, Chadi G Abdallah, Ruth Lanius, Maria Densmore, Jean Théberge, Richard W J Neufeld, Paul M Thompson, Rajendra A Morey

Faculty, Staff and Students Publications

The thalamus is a heterogeneous structure crucial for corticocortical communication, affective–perceptual integration, motor preparation, and memory-related functions. Posttraumatic stress disorder (PTSD) is characterized by various symptoms that likely relate to thalamic functions. Group-level and individual differential structural covariance (SC) analyses were conducted on intrathalamic, thalamocortical, and thalamosubcortical volumetric networks by segmenting structural MRI data from 2,784 subjects (PTSD n = 1,306; controls n = 1,478) into 25 thalamic nuclei per hemisphere. We found that PTSD was associated with stronger intrathalamic and thalamocortical network strength and stronger SC between the limbic thalamus and the somatomotor and auditory thalamus. PTSD severity was …


Professionalism In Practice: A Novel Approach To Integrating Small Doses Of Case-Based Professionalism Education Into Monthly Grand Rounds., Allison H Taylor, Andrew Caruso, Kelley Arredondo, Ellen M Friedman, Stacey R Rose Jan 2026

Professionalism In Practice: A Novel Approach To Integrating Small Doses Of Case-Based Professionalism Education Into Monthly Grand Rounds., Allison H Taylor, Andrew Caruso, Kelley Arredondo, Ellen M Friedman, Stacey R Rose

Faculty, Staff and Students Publications

Introduction: Professionalism is a critical construct across the health professions, though learners and faculty report feeling underprepared to navigate difficult situations; education in professionalism is challenged by the absence of a universal definition, time constraints due to overcrowded curricula, and the lack of consistent messaging to learners and faculty.

Methods: Professionalism in Practice (PiP) was developed to provide small doses (∼5 minutes) of case-based professionalism education as part of an existing educational forum (Grand Rounds) to optimize attendance of both learners and faculty. Each vignette highlighted a common professionalism challenge and was aligned with an AAMC professional competency. Sessions were …


Sodium Supplementation Algorithm To Promote Growth In Infants Who Are Preterm: Randomized Clinical Trial, Brianna M Liberio, Gregory M Sokol, Hannah Rakow, Kelly Mosesso, Valerie Hole, William W Wong, Shaji K Chacko, Jeffrey L Segar Jan 2026

Sodium Supplementation Algorithm To Promote Growth In Infants Who Are Preterm: Randomized Clinical Trial, Brianna M Liberio, Gregory M Sokol, Hannah Rakow, Kelly Mosesso, Valerie Hole, William W Wong, Shaji K Chacko, Jeffrey L Segar

Faculty, Staff and Students Publications

Objective: Evaluate the effectiveness of an algorithm using urine sodium (Na) concentration to guide dietary Na supplementation compared with standard care to promote growth in infants who are preterm.

Methods: A randomized trial was conducted in 4 neonatal units in Indianapolis, Indiana, involving infants between 250/7 to 296/7 weeks gestation with birthweight > 500 g. Study arms consisted of standard care or use of algorithm beginning at 14 to 17 days postnatal age. The primary outcomes were somatic growth (weight, length, and head circumference) measured by change in Z-score between aged 2 weeks and 36 weeks postmenstrual age (PMA). Secondary outcomes …


Cultured Ex Vivo Human Brain Tissue Maintains Cell-Type Transcriptional Identities, J P Mcginnis, Sai Mallannagari, Maria Camila Guevara, Joshua Ortiz-Guzman, Benjamin D W Belfort, Suyang Bao, Snigdha Srivastava, Maria Morkas, Emily Ji, Kalman A Katlowitz, Angela Addison, Evelyne K Tantry, Carrie A Mohila, Melissa M Blessing, Nisha Gadgil, Samuel G Mcclugage, David F Bauer, William E Whitehead, Guillermo Aldave, Omar Tanweer, Naser Jaleel, Ali Jalali, Akash J Patel, Sameer A Sheth, Howard L Weiner, Shankar Gopinath, Ganesh Rao, Akdes Serin Harmanci, Daniel Curry, Benjamin R Arenkiel Jan 2026

Cultured Ex Vivo Human Brain Tissue Maintains Cell-Type Transcriptional Identities, J P Mcginnis, Sai Mallannagari, Maria Camila Guevara, Joshua Ortiz-Guzman, Benjamin D W Belfort, Suyang Bao, Snigdha Srivastava, Maria Morkas, Emily Ji, Kalman A Katlowitz, Angela Addison, Evelyne K Tantry, Carrie A Mohila, Melissa M Blessing, Nisha Gadgil, Samuel G Mcclugage, David F Bauer, William E Whitehead, Guillermo Aldave, Omar Tanweer, Naser Jaleel, Ali Jalali, Akash J Patel, Sameer A Sheth, Howard L Weiner, Shankar Gopinath, Ganesh Rao, Akdes Serin Harmanci, Daniel Curry, Benjamin R Arenkiel

Faculty, Staff and Students Publications

There is growing recognition of the need for human-based models of the nervous system and its diseases. Studies have investigated the electrophysiological properties of neurons in ex vivo human brain tissue, but the maintenance of other cell types remains unclear. We therefore used single-nucleus RNA sequencing of six patient samples to determine how well various cell types maintain their transcriptional identities over two weeks in organotypic slice culture (day 0, with 83 501 nuclei, and day 14, with 45 738). For each patient sample (two pediatric temporal lobectomies, one adult frontal cortex, two glioblastomas, and one medulloblastoma), we generated correlations …


Toward Ethical Provenance Tracking: The Ga4gh Model Data Access Agreement (Daa), Alexander Bernier, Bartha Maria Knoppers, Jonathan Lawson, Robyn Mcdougall, Maili Raven-Adams, Vasiliki Rahimzadeh Jan 2026

Toward Ethical Provenance Tracking: The Ga4gh Model Data Access Agreement (Daa), Alexander Bernier, Bartha Maria Knoppers, Jonathan Lawson, Robyn Mcdougall, Maili Raven-Adams, Vasiliki Rahimzadeh

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Standardizing contractual clauses that govern data access enables research institutions to responsibly steward genomic and related health data while enabling its efficient downstream reuse.

Methods: We describe a document analysis study using both qualitative and comparative law analytical approaches to identify the most common categories of clauses from 29 different data access agreements used by human biomedical research consortia globally. We furthermore characterized the legal positions and standard practices for each common element of the agreement and synthesized across them to develop model clauses. A total of 3 discussion sessions were organized virtually to refine the clauses among members …


Imagining Genomics And Population Health In 2050: Anticipating Future Research, Policy, And Governance Needs, Bartha Maria Knoppers, Yann Joly, Ma Apos N H Zawati, Habiba Alsafar, Jeffrey C Barrett, Laura Blackburn, Brian Hon-Yin Chung, Martina C Cornel, Edward S Dove, David Glazer, Calvin Wai-Loon Ho, Muin J Khoury, Anna C F Lewis, Anneke Lucassen, Peter F R Mills, Colin Mitchell, Nicola Mulder, Ainsley J Newson, Anthony Ng, Paul D P Pharoah, Vasiliki Rahimzadeh, Megan C Roberts, Saskia C Sanderson, Jeffrey M Skopek, Ron Zimmern, Eric M Meslin Jan 2026

Imagining Genomics And Population Health In 2050: Anticipating Future Research, Policy, And Governance Needs, Bartha Maria Knoppers, Yann Joly, Ma Apos N H Zawati, Habiba Alsafar, Jeffrey C Barrett, Laura Blackburn, Brian Hon-Yin Chung, Martina C Cornel, Edward S Dove, David Glazer, Calvin Wai-Loon Ho, Muin J Khoury, Anna C F Lewis, Anneke Lucassen, Peter F R Mills, Colin Mitchell, Nicola Mulder, Ainsley J Newson, Anthony Ng, Paul D P Pharoah, Vasiliki Rahimzadeh, Megan C Roberts, Saskia C Sanderson, Jeffrey M Skopek, Ron Zimmern, Eric M Meslin

Center for Medical Ethics and Health Policy Staff Publications

No abstract provided.


Access To Digital Health Technologies: Personalized Framework And Global Perspectives, Sanjiv M Narayan, Mina K Chung, Demilade Adedinsewo, Luisa C C Brant, Leslie L Davis, David Duncker, Jennifer L Hall, Janet K Han, Carolyn S P Lam, Eldrin Lewis, Joseph Loscalzo, Manlio F Márquez, Vasiliki Rahimzadeh, Fatima Rodriguez, Prashanthan Sanders, Emma Svennberg, Kenneth Stein, Mintu Turakhia, Clyde Yancy, Antonis A Armoundas Jan 2026

Access To Digital Health Technologies: Personalized Framework And Global Perspectives, Sanjiv M Narayan, Mina K Chung, Demilade Adedinsewo, Luisa C C Brant, Leslie L Davis, David Duncker, Jennifer L Hall, Janet K Han, Carolyn S P Lam, Eldrin Lewis, Joseph Loscalzo, Manlio F Márquez, Vasiliki Rahimzadeh, Fatima Rodriguez, Prashanthan Sanders, Emma Svennberg, Kenneth Stein, Mintu Turakhia, Clyde Yancy, Antonis A Armoundas

Center for Medical Ethics and Health Policy Staff Publications

The emergence and rapid adoption of digital health technologies (DHT) present unprecedented opportunities to democratize and reduce disparities in health care by monitoring health and disease at the point of care in all patients. However, limited access to DHT is becoming a major obstacle to realizing these goals. Access to DHT is influenced not only by well-recognized social determinants of health, but also by digital determinants of health, such as digital literacy and the need for broad access to digital infrastructure, as well as commercial and economic factors. Addressing these challenges and designing unbiased systems of care are essential to …