Digital Commons Network^™

The Addict, Lacy M. Johnson

Creative Nonfiction Magazine

No abstract provided.

Grave Robber: A Love Story, Joyce Marcel

Creative Nonfiction Magazine

No abstract provided.

Speaking Of Ears And Savagery, Steven Church

Creative Nonfiction Magazine

No abstract provided.

Encounter: Erik Larson 1

Creative Nonfiction Magazine

No abstract provided.

Quotidian Nonfiction, Patrick Madden

Creative Nonfiction Magazine

No abstract provided.

A Murderer’S Work, J. Nicholas Geist

Creative Nonfiction Magazine

No abstract provided.

Blot Out, Colleen Kinder

Creative Nonfiction Magazine

No abstract provided.

Then & Now, Adam Regn Arvidson

Creative Nonfiction Magazine

No abstract provided.

Exogenous Myrosinase From Mustard Seed Increases Bioavailability Of Sulforaphane From A Glucoraphanin-Rich Broccoli Seed Extract In A Randomized Clinical Study, Angela Mastaloudis, Lola Holcomb, Jed W. Fahey, Camila Olson, David C. Nieman, Colin Kay, Robert O'Donnell, Alessandra Pecorelli, Marissa Kinney, Yanyan Li, Suzanne L. Ishaq, Giuseppe Valacchi

Pharmacy Faculty Scholarship

Inactive glucoraphanin (GR) in broccoli is converted to the antioxidant, anti-inflammatory, and anti-bacterial sulforaphane (SF) by cruciferous vegetable enzyme myrosinase (Myr), or similar enzymes from specific gut bacteria; both sources have variable efficiency. The effects of exogenous Myr on the conversion efficiency of GR to SF was compared to gut microbial Myr-like activity. In a randomized, double-blind, crossover study, sixteen subjects (9 F: 7 M) received a single oral dose of GR in broccoli seed extract with Myr-containing mustard seed powder, or broccoli seed extract alone, both with ascorbic acid. GR + Myr, on average, doubled the bioavailability of SF …

Evolving Strategies In Prostate Cancer: Emerging Approaches And Unmet Needs From The Bridging The Gaps In Prostate Cancer Expert Panel, Rana Mckay, Benjamin Maughan, Alicia Morgans, Neal Shore, Evan Yu, Ravi Madan, Jacob Berchuck, Bradley Carthon, Steven Finkelstein, Leonard Gomella, Michael Gorin, Andrew Hahn, Stacy Loeb, Vivek Narayan, Daniel Petrylak, Charles Ryan, Karine Tawagi, Phuoc Tran, Tanya Dorff

Department of Urology Faculty Papers

BACKGROUND: The expansion of treatment options for prostate cancer (PC) has improved disease-specific and overall survival outcomes but has also raised questions about the optimal level of treatment needed for patients based on their individual prognosis and accounting for potential toxicity, incorporating quality of life considerations.

METHODS: A panel of experts met to discuss current controversies in the care of patients with PC across the disease continuum. Multidisciplinary experts review advances and persistent uncertainties in biomarker-guided assessment, imaging, and systemic therapy for prostate cancer. The discussion outlines priority gaps in evidence that must be addressed to optimize individualized patient care. …

Two Decades Since Cms V. Argentina: Concession Contracts, Necessity Doctrine, And The Imf’S Impact On Sovereign Economic Governance, Esraa S. Saied Abdallah

Theses and Dissertations

In the evolving landscape of international trade, particularly within the framework of Bilateral Investment Treaties (BITs), the primary aim has been to promote and protect foreign investment. The 1980s witnessed a notable increase in investment treaties, coinciding with a global shift toward privatization that was significantly influenced by the impact of international financial institutions, including the International Monetary Fund (IMF) and the World Bank. By the 1990s, BITs had evolved to offer specific guarantees aimed at reducing the risks foreign investors faced in host states. However, despite the growth and transformation brought about by foreign investments, disputes arising under investment …

Mechanized Tube Well Installation, Robert M. Stwalley Iii, Grace L. Baldwin Kan-Uge, Roger Tormoehlen

Purdue University Press Books

Mechanized Tube Well Installation provides detailed information on the design development of a mechanized means to install shallow tube wells using a hydraulic driver attached to a small vehicle. This book explores the creation of this technique through the merging of available components, selection of the components, testing of the assembly, and the driving of wells. It also provides comprehensive coverage of state-of-the-art engineering, technology, and best practices as they relate to driving water wells for human consumption, animal care, and irrigation. Mechanized Tube Well Installation is well-aligned with collegiate humanitarian aid, environmental and natural resources engineering, and agricultural equipment …

Teaching Integrated Stem In Middle School, S. Selcen Guzey

Purdue University Press Books

Teaching Integrated STEM in Middle School is a valuable resource for educators, researchers, and policymakers who are committed to furthering integrated STEM education. Through a review of the literature on the topic, the volume offers a clear understanding of the impact of integrated STEM education on instructors’ teaching practices and student outcomes. The book presents a framework and instructional guide that educators can utilize to develop new curricular materials. Two sample units—focused on designing a two-stage water filter and formulating sunscreen—provide step-by-step guidance for lesson implementation and offer strategies for assisting students as they use engineering models to devise design …

Ancient Wisdoms For Modern Crises: Learning From Laozi’S “Daodejing”, Steve Hallett

Purdue University Press Books

We live in a time of abundance and comfort for some, scarcity and hardship for others—a period that seems to have all of us teetering on the brink. Certainly, there is no lack of modern crises, but do we possess the wisdom to overcome them, and where might we seek that wisdom? Ancient Wisdoms for Modern Crises: Learning From Laozi’s “Daodejing[JR1] [ED2] [NN3] ” looks to the Daodejing, a text written during the late Zhou Dynasty (600–400 BCE), for guidance. One of the core treatises of Eastern philosophy, it advocates humility, simplicity, and sustainable living. As both a …

Protocols In Root-Microbe Interactions, Anjali S. Iyer-Pascuzzi

Purdue University Press Books

Protocols in Root-Microbe Interactions describes laboratory protocols that have been developed and optimized for scientists working in root-microbe interactions, specifically for those wanting to quantify immune responses in plant roots. The experiments are focused on cellular to whole-root scale and include molecular biology, biochemistry, and histology techniques. Written in an easy-to-understand fashion that is suitable for both early career and experienced scientists, the protocols were optimized for tomato roots but can easily be adapted to roots of other plant species, or if needed, to leaves. The book includes information on quantifying pattern-triggered immune (PTI) responses in plant roots and covers …

Market Signals From Online Behavior, Nicole J. Olynk Widmar, Michael L. Smith, Erin Robinson

Purdue University Press Books

Market Signals From Online Behavior asks, What do social media trends, Google searches, and online chatter reveal about consumer behavior? It also poses the question, How can we interpret these signals without losing sight of the people behind the posts? This book examines the digital traces left by consumers and explores how these signals intersect with food, agriculture, retail, and beyond.

Drawing from real-time data and social-listening analysis, Market Signals connects the dots between what is trending online and what it means for markets in the real world. Whether it is the rise of plant-based eating, changing holiday shopping norms, …

Horse Evaluation: A Multibreed Text For Competitive Youth Equine Judges, Colleen M. Brady

Purdue University Press Books

Horse judging is one of the most popular activities in 4-H, FFA, and other youth-development organizations. Judging teaches youth how to both critically analyze animals based on a specific set of criteria and justify their decisions through oral reasoning. This book includes information on examining a wide variety of breeds—from quarter horses and Arabians to Saddlebreds, Drafts, and Miniatures—and covers a range of disciplines. Both halter and performance classes are explored, and the rules and regulations used to govern contests at the national level are provided. Example sets of reasons are supplied for most classes, as are lists of potential …

Assessing Knowledge, Attitudes, And Practices (Kap) Towards The One Health Approach In Governmental Officers In Egypt, Nour Elsersawy

Theses and Dissertations

Background: the one health (OH) approach emphasizes the interconnectedness among human, animal, and environmental health and requires multisectoral collaboration to address complex health challenges. Egypt faces significant threats at the human-animal-environment interface, including endemic and emerging zoonotic diseases, antimicrobial resistance (AMR), food safety challenges, and vector-borne diseases. Despite established coordination mechanisms and the launch of the One Health National strategic framework (2023-2027) of Egypt, the extent to which oh principles are understood, embraced, and practiced by governmental officers responsible for implementation remains incompletely understood. Objectives: this study assessed and evaluated the knowledge, attitudes, and practices (KAP) regarding the one health …

Groove Goes The Distance: An Initial Inquiry Into Jazz Music In Egypt, Farida Gohar

Theses and Dissertations

Jazz music has been a historically contentious site of social, cultural, and political signification. From the violent subjugation that characterized its origins and aspirational freedom that animated its practice, to its transformation into a distinctly “American” music instrumentalized by the US State Department to counter Soviet influence, jazz’s capacity for the inscription of meaning is vast and regularly cause for debate. The particular configuration of jazz music in Egypt is no less complicated although seldom studied. This thesis ventures an initial mapping of the dynamics and negotiations that historically defined the initiation of “Egyptian” jazz, as well as the ones …

Law And The (Re)Production Of Class Hierarchies In Egypt, Ahmad Abdelnaby

Theses and Dissertations

This thesis investigates how Egypt’s legal system, structurally tilted toward the elite and constitutive of inequality, has interacted with the country’s entrenched culture of class-based discrimination to produce a legal culture uniquely comfortable with hierarchy. It contends that class-based discrimination in Egypt has evolved from a social prejudice into a juridical condition, one in which the law does not merely mirror inequality but actively constructs and rationalizes it. By examining the intersection between legal structure and Egypt’s entrenched moral order of class-based discrimination, the study reveals a legal culture that no longer hides its hierarchies behind the veil of neutrality …

Investigating Tau Pathology In The Retina And Anterior Segment Structures Of The Eye In A 3-Nitropropionic Acid–Induced Tauopathy Mouse Model, Mohamed Sayed Ahmed Abdel-Kader Qasem

Theses and Dissertations

Background and Objectives: Alzheimer's disease, the most prevalent neurodegenerative disorder in older adults, is characterized by accumulation of hyperphosphorylated tau and amyloid-beta (Aβ) plaques in the central nervous system. Given the retina's shared embryological origin with the brain, its direct neural connectivity via the optic nerve, and similarities in vasculature and age-related degeneration patterns, retinal pathology may serve as an early, non-invasive biomarker for Alzheimer's disease. This study employed 3-nitropropionic acid (3NP) as a pathway-specific tauopathy model driven by mitochondrial dysfunction. The study particularly aimed to investigate whether retinal and corneal tau pathology reflects underlying tau-related neurodegeneration triggered by …

Metagenomic Profiling Of Gut Microbiome Signatures Across Liver Disease Stages And Hcv-Related Hepatocellular Carcinoma In Egyptian Patients, Marwa A. Zahra

Theses and Dissertations

Dysbiosis in the gut microbiome, particularly concerning the synchronous crosstalk between the gut and the liver, has been associated with various diseases. This study profiles the gut microbiome in liver diseases among Egyptian patients, with a focus on the hepatitis C virus (HCV) and hepatocellular carcinoma (HCC), both of which are highly prevalent in Egypt. Utilizing shotgun metagenomic sequencing, we analyzed microbial gene catalogs and taxonomic profiles from 46 Egyptian patients categorized into five groups: healthy individuals, liver disease patients of different etiologies, post-HCV, treated HCV, and HCV-HCC patients. Healthy and treated HCV patients exhibited distinct microbial profiles characterized by …

Refugees In Egypt: State Framing, Ministerial Narratives, And The Politics Of Representation On Social Media, Habiba Kohail

Theses and Dissertations

This study examines Egyptian government discourse on refugees in 2024, a year characterized by heightened regional displacement and the enactment of Egypt’s first Asylum Law (Law No. 164 of

2024). Using a multidisciplinary framework that combines framing analysis with van Dijk's socio-cognitive approach, the study systemically analyzes how the government construct refugees on social

media and sets the boundaries of their inclusion in Egypt.

The thesis analyzes the Egyptian government discourse on refugees across official social media platforms from January 1, 2024, to December 31, 2024, a period that witnessed an increase in the government engagement in the refugee issue …

Prephiral Bacterial Infectious Agent Triggers Neuroinflammatory Responses And Neurobehavioral Impairment In Wild-Type Mice, Hadeer Atalah

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's and Parkinson's, present an increasing global challenge, with chronic neuroinflammation identified as a principal factor alongside genetic, environmental, and infectious influences (Boyd et al., 2022).  Epidemiological data associate bacterial infections with a 40% heightened risk of Parkinson's disease; however, the mechanisms—especially the direct connection between peripheral sepsis and the silent onset of central nervous system pathology absent acute meningitis—are inadequately investigated (Smeyne et al., 2021), particularly concerning common pathogens like Klebsiella pneumoniae in high-burden areas such as Egyptian ICUs, where it constitutes 30% of cases (Alkompoz et al., 2023). This study filled the gap by creating …

The Indeterminacy Of Customary International Law, Mohamed Diaa Tawfik

Theses and Dissertations

This thesis explores the judicial formation of customary international law and examines how international courts oscillate between interpretive and law-making functions. It analyzes key theoretical frameworks—including Kelsen’s Pure Theory of Law, Dworkin’s Law as Integrity, Kennedy’s radical indeterminacy, and Koskenniemi’s Descending-Ascending Approach—to understand how courts assert and shape customary norms beyond mere state practice and opinio juris. The work concludes that the International Court of Justice and other tribunals increasingly act as de facto lawmakers under the guise of interpretation, advocating the indeterminacy they try to avoid.

Reconfiguring The Category Of 'Sudan' Through The Literary Field: Representation, Disposability, Ambiguity And The 'Magical' In Four Post-Colonial Novels (2002-2022), Mourad Farahat

Theses and Dissertations

In this thesis I shall argue that contemporary African literature, with ‘’both its ethnographic imagination and anthropological complexity’’ (Orock, 2022, p.3), its use of ‘disruptive’ characters, and its focus on the embeddedness of the ‘collective’, the ‘common’ and the ‘vulgar’ in the personal (Mbembe, 2003), may help us mitigate some social scientific limitations on the study of Africa, and may aid us in understanding relations of power within the post-colony. I seek to show how contemporary Sudanese literature has already moved beyond the fixed social categories, lines, and limits which dominate some of the social scientific literature on Sudan. Literature …

Uncovering Potential Therapeutic Targets For Spinal Cord Injury; Insights From Single-Cell And Cross-Species Transcriptomics, Sara Samy Abouzekry

Theses and Dissertations

Central nervous system (CNS) injury remains a devastating healthcare problem. Despite years of research, it remains almost impossible to achieve meaningful functional repair following traumatic brain injury (TBI) and spinal cord injury (SCI). Spinal cord injury (SCI), a highly devastating subset of CNS trauma, is considered a challenge due to the extremely limited regenerative capacity of the nervous system in adult mammals. In contrast, certain species display remarkable repair abilities followed by moderate regenerative ability in neonatal mammals, indicating that regeneration is shaped by the evolutionary context as well as the developmental age.

To uncover the core molecular mediators of …

Research As A Reciprocal Act: How Rural Grade 5 And 6 Co-Researchers Transformed Their Adult Research Mentors, Bonnie Stelmach, Leah Peters, Rae Ann Van Beers

The Qualitative Report

Including children and youth in research contributes to their academic and life skills development, but how do co-researching experiences transform adult mentors?  Walkerdine (1997) stated that research “provides not only ways of seeing others, but ways of understanding ourselves” (p. 15). In this spirit, we report on our experiences to share how co-researching with eight Grade 5 and 6 students in a rural K-9 school in Alberta, Canada, which gave us insights into research and teaching assumptions and practices. Data were collected from observations of the students co-conducting interviews with K-6 research participants, students’ self-assessments of their co-researching experiences, transcripts …

A Learning Model For Effective Literacy Instruction In Diverse Papuan Contexts, E. Oos M. Anwas, Anggi Afriansyah, Muhammad Mulyadi, Dwi Purwoko, Zulfikri Anas, Virgiawan Listanto, Dini Dwi Kusumaningrum, Fikri Muslim, Dayu Rifanto

The Qualitative Report

This study seeks to address the persistent challenge of low literacy rates among Papuan primary school children by answering the research question: What factors hinder literacy development, and how can a holistic learning model improve literacy outcomes in this context? Conducted in Keerom and South Manokwari Regencies, the research adopts a qualitative approach to design an inclusive and effective learning model. The study involved a multi-stakeholder approach, engaging primary school students, educators (teachers and principals), parents, community leaders (village heads, religious leaders, and traditional leaders), government officials (education office and local government), legislative representatives (DPRD members), and academic experts from …

Does Increasing Human Impact Across The Holocene Result In Simplification Of Vegetation Composition And Diversity Across Europe? A Pollen-Based Spatio-Temporal Approach, Caterina Röhm, Maria Antonia Serge, Ralph Fyfe, François Gillet, Laurent Marquer, Agnès Lagnoux, Thierry Klein, Didier Galop, Florence Mazier

School of Geography, Earth and Environmental Sciences

Land use and climate change are the primary drivers of current biodiversity loss, but have had different impacts on biodiversity across the Holocene epoch. To enhance our understanding of current changes in diversity and its impact on ecosystem functions, knowledge of long-term interactions between vegetation diversity, land use change, and climatic change is crucial. Grid-cell estimates of quantified regional vegetation cover (RV_est) based on pollen data from 1607 sites across Europe, transformed using the REVEALS (Regional Vegetation Estimates from Large Sites) model, have been used to explore spatiotemporal changes in vegetation and regional diversity during the Holocene (25 …