Digital Commons Network^™

Hiv Infection, Neurotoxicity, Inflammation, Premature Aging, And Therapeutic Challenges To Plwh: An Overview, Mudit Tyagi, Ulhas P. Naik, Kratika Tyagi, Madhulika Sharma, Gagan Kaushal, Alok Bhushan, Michael Bukrinsky, Priya Tyagi

Department of Medicine Faculty Papers

HIV infection remains a major global health challenge due to its complex pathogenesis and lifelong persistence in people living with HIV (PLWH). A central barrier to eradication is the virus's ability to establish long-lived latent reservoirs in different tissues, including the central nervous system (CNS), where it evades immune clearance and antiretroviral therapy (ART). These reservoirs, seeded early during infection, fuel viral rebound if ART is interrupted, requiring lifelong treatment. In the CNS, HIV persists despite systemic viral suppression because of limited ART penetration across the blood-brain barrier (BBB), and infection of long-lived cells such as microglia and perivascular macrophages. …

Coordinated Stimulation Of Axon Regenerative And Neurodegenerative Transcriptional Programs By Atf4 Following Optic Nerve Injury, Preethi Somasundaram, Madeline M Farley, Melissa A Rudy, Katya Sigal, Andoni I Asencor, David G Stefanoff, Malay Shah, Puneetha Goli, Jenny Heo, Shufang Wang, Nicholas M Tran, Trent A Watkins

Faculty, Staff and Students Publications

Stress signaling is important for determining the fates of neurons following axonal insults. Previously, we showed that the stress-responsive kinase PERK contributes to injury-induced neurodegeneration (Larhammar et al., 2017). Here, we show that PERK acts primarily through activating transcription factor-4 (ATF4) to stimulate not only pro-apoptotic but also pro-regenerative responses following optic nerve damage. Using conditional knockout mice, we find an extensive PERK/ATF4-dependent transcriptional response that includes canonical ATF4 target genes and modest contributions by C/EBP Homologous Protein (CHOP). Overlap with c-Jun-dependent transcription suggests interplay with a parallel stress pathway that orchestrates regenerative and apoptotic responses. Accordingly, neuronal knockout of …

Deception And Deception Mitigation In Multi-Agent Systems, Nancirose Piazza

Doctoral Works at the University of New Haven

In multi-agent learning systems where agents interact in dynamic and complex environments, cooperation, coordination and communication are fundamental to achieving collective or individual goals. However, the rise of both emergent and induced deceptive behaviors pose significant challenges to system integrity and performance. Emergent deception and deceptive behaviors may manifest as a result of objective misalignment or incomplete situational awareness, leading to systematic failure in coordination. Agents that engage in intentional deceptive behaviors manipulate outcomes for their self-interest, undermining the fairness, security and reliability of these systems. Modeling and mitigating these forms of deception is critical to not only ensure effective …

Pest Management For Utah Cut Flower Production: Insects And Their Relatives, Nick Volesky, Marion Murray, Melanie Stock

All Current Publications

Pest management is important in cut flower production, marketability, and farm profitability. This fact sheet focuses on animal pests (insects, arthropods, mollusks, and vertebrates), not diseases or weeds, and has two parts. Part 1 applies Integrated Pest Management (IPM): using preventive techniques, pest thresholds, and best management practices with pests in cut flower crop production. Part 2 highlights the top 10 common pests of cut flowers in Utah and their management.

The Current - Volume 36 Issue 7, Nova Southeastern University

Student Newspapers

No abstract provided.

Spartan Daily, February 26, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 16

Decyl Caffeate Inhibits The Proliferation Of Human Triple-Negative Breast Cancer Cells, Che-Yi Chao, Woei-Cheang Shyu, Chih-Lung Lin, En-Pei Isabel Chiang, Yueh-Hsiung Kuo, Feng-Yao Tang

BioMedicine

Background: Over recent decades, considerable attention has been directed toward the discovery of novel compounds capable of targeting survival-related signaling networks as therapeutic candidates for triple-negative breast cancer (TNBC). Central to TNBC pathobiology are the Akt/mTOR and MAPK/ERK signaling axes, both contribute to tumor progression and therapeutic resistance. Caffeic acid (CA), a naturally derived phenolic compound with anti-inflammatory activity, has previously been investigated for its anti-cancer potential. Purpose: In the present study, we explored the therapeutic value of newly synthesized CA derivatives in TNBC models using both cellular and animal-based systems. Methods: The anti-tumor efficacy of these CA derivatives was …

Increased Dairy Product Consumption Is Associated With Shorter Telomere Length In Buccal Cells Among Normotensive Adults, Hsin-Hwa Tsai, Yang-Di Su, Zi-Lun Lai, Chia-Yu Lin, Shu-Fan Lin, Hsiu-Ching Hsu, Wen-Yuan Lin, Po-Ren Hsueh

BioMedicine

Background: Telomere length (TL) is a biomarker of biological aging and a predictor of age-related diseases. Dietary patterns, including dairy consumption, may influence telomere dynamics, but the evidence remains limited, particularly in Asian populations. This study investigates the association between dairy consumption and relative telomere length (RTL) in Taiwanese adults, with results analyzed by hypertension status.

Methods: A cross-sectional survey was conducted among 259 adults in Taipei, Taiwan. RTL was measured using quantitative PCR from buccal cells. Dietary intake was assessed through self-reported questionnaires, with a focus on dairy frequency and fat content. Multiple linear regression models were used to …

Empathy Training Program As A Strategy To Improve Empathy In Elementary School Students, Rizqi Hanabella

Jurnal Pendidikan Humaniora

This study examined the effectiveness of an empathy training program for elementary school students using a non-randomized quasi-experimental design (untreated control group with pretest-posttest and follow-up measurements). The participants were 39 students from Grade IV and Grade V who were assigned to groups based on existing class membership. The program was developed from Davis's empathy framework (perspective-taking, fantasy, empathic concern, and personal distress), and empathy was measured using an Interpersonal Reactivity Index based scale adapted for elementary students. Data were analyzed using a mixed-design ANOVA. The findings showed a significant time-by-group interaction, and the experimental group demonstrated a significant increase …

Book Review: Gone Feral: Unruly Women And The Undoing Of Normative Femininity, Ali Saha

Journal of International Women's Studies

No abstract provided.

The Translucent Culprit, Cammie Tolleshaug

Fresh Voices: Composition at Cal Poly

No abstract provided.

To What Extent?, Carson Dangberg

Fresh Voices: Composition at Cal Poly

No abstract provided.

Not A Monster, Jessica Hadley

Fresh Voices: Composition at Cal Poly

No abstract provided.

In Vitro Meat: Unnatural Or Life Saving, Joseph Coplon

Fresh Voices: Composition at Cal Poly

No abstract provided.

Defying Gender Roles With Friendship And Ponies, Liam Gow

Fresh Voices: Composition at Cal Poly

No abstract provided.

Wild Child, Dylan Grant

Fresh Voices: Composition at Cal Poly

No abstract provided.

Almost Heaven, Nicholai Busch

Fresh Voices: Composition at Cal Poly

No abstract provided.

A Beautiful Failure, Lydia Kwong

Fresh Voices: Composition at Cal Poly

No abstract provided.

Chipotle: "Food With Integrity", Emily Cheung

Fresh Voices: Composition at Cal Poly

No abstract provided.

A Pep Talk, Kaitlyn Krautkramer

Fresh Voices: Composition at Cal Poly

No abstract provided.

Not My Clay Doll, Kiana Chan

Fresh Voices: Composition at Cal Poly

No abstract provided.

Have You Ever Heard Of A Louisiana Tree Dog?, Alex Batta

Fresh Voices: Composition at Cal Poly

No abstract provided.

The Local Outsider: Sleeping Sickness Drug Trials, Social Exclusion, And Responses Of Women In The Uyui District Of Tanzania, 1964-2005, Hamisi M. Machangu

Journal of International Women's Studies

Unethical practices in sleeping sickness drug trials conducted in the Uyui District of Tanzania from 1964 to 2005 resulted in physical and psychological disabilities among participants and contributed to the social exclusion of its women participants. Although these practices are understood to have caused disabilities, existing studies have overlooked their contribution to the social exclusion of women. Drawing from both primary and secondary sources, this article treats the impact of such practices as a window to examine the nature and dimensions of social exclusion of women with disabilities and how these women responded to social exclusion at the grassroots level. …

Bodies And Beyond: Reading Liminal Corporealities In Ambai’S Short Stories, Keerthana S

Journal of International Women's Studies

This article demonstrates how the Indian writer Ambai’s short stories construct counter-narratives to phallogocentric structures, opening up fresh avenues of theoretical engagement in the cultural context of Tamil Nadu, India. Despite advancements towards gender equality, cultural symbols and metaphors such as tali (ornament worn by Tamil women denoting their marital status), karpu (chastity), and veera tai (valorous mother), often govern the lives of women to a great extent. I argue that Ambai’s stories both resist the hegemonic constraints of such cultural symbols and also endeavour to reconfigure them. Ambai’s renderings of cultural semiotics enable women to experience their bodies removed …

Recasting The Sacred: Gendered Embodiments In The Shadow Puppet Theatre Of Kerala, V. K. Karthika

Journal of International Women's Studies

Tholppavakkoothu, traditional leather shadow puppetry from Kerala, a southern state within India, has long been performed in temples as a sacred ritual. This ritual art form was a male-dominated performance in which ideas regarding physical purity (in connection with menstruating female bodies) excluded women from participating. Such patriarchal codifications were challenged when Pentholppavakkoothu, an all-women leather puppetry troupe, emerged in 2021, as it not only took the art outside temple premises but enabled the participation of women in the making and performance of the art. This paper critiques the gender dynamics within Tholppavakkoothu, analysing how cultural rituals and body politics …

Feminist Reflexivity In Practice: Addressing Positionality And Building Sisterhood Through Fieldwork With Black Migrant Sex Workers In Istanbul, Yeliz Kendir-Gök

Journal of International Women's Studies

This article addresses feminist reflexivity and researcher positionality in ethnographic fieldwork with undocumented Ugandan women sex workers in Istanbul’s Tarlabaşı and Aksaray neighborhoods. Drawing on fourteen months of immersive research, including participant observation, semi-structured interviews, and reflexive journaling, the study examines how both the researcher and participants engaged in strategic forms of resistance within racialized and gendered urban spaces. The analysis is grounded in a feminist epistemological framework that draws on Kandiyoti’s notion of patriarchal bargaining and Scott’s theory of hidden transcripts. Findings reveal how participants and the researcher used subtle forms of resistance, such as strategic silence or performative …

Whose Rules, Whose Rights?: Conflict-Related Sexual Violence And Legal Protections In Wartime, Sadaf Shabbir

Journal of International Women's Studies

This article critically analyzes conflict-related systematic sexual violence (CRSV) within the frameworks of international humanitarian law, particularly the Geneva Conventions and the 1977 Additional Protocols. Moving beyond viewing CRSV as an isolated atrocity, it situates sexual violence within the historical and political roots of conflict, using case studies from the Democratic Republic of Congo and the Syrian Arab Republic. The analysis demonstrates how sexual violence operates as a weapon within exploitative wartime economies, where institutional collapse and illicit resource networks enable the commodification and control of women’s bodies. Furthermore, the article introduces a sectarian lens to the study of CRSV, …

An Archival Responsibility: A Scoping Review Of Literature Regarding The Documentary Burdens Of Refugees, Ana Roeschley, Kinza Alizai, Crystal Tharayil, Amy Lanier, Merrion D. Frederick, Homero R. Cuevas

Journal of Contemporary Archival Studies

Documented individuals who do not live in conflict zones can usually access and use their records to migrate, begin new careers, enroll their children in educational institutions, and gain access to healthcare through mostly routine record-related procedures. However, these standard processes become impossible obstacles for refugees when they lose access to their personal records as part of their forced displacement. Though ever-present for refugees, these documentary burdens are compounded in times of societal crises and political upheaval—times when documentation is most critical. If archivists and archival scholars are to address these issues, it is important to understand the scope of …

The Soul Of Reading: Broadside Lotus Press And Black Poetry As Celebration And Resistance, Leah Van Belle

Michigan Reading Journal

No abstract provided.

Author Talks In A Virtual Graduate Literature Course, S. Rebecca Leigh

Michigan Reading Journal

In a graduate, online course, seven invited guests – a combination of authors and illustrators, some of whom are Michiganders – spoke to 18 graduate students and practicing teachers, about books, writing, illustrating for children, and trends in education today. This is a literature course that is guided by the questions, “What are current topics and issues connected to literature today?,” and “How might we rise above these challenges that puts contemporary literature in the hands of students?”