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Full-Text Articles in Entire DC Network
Spartan Daily, March 5, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, March 5, 2026, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, 2026
Volume 166, Issue 19
Judicial Independence As A Constitutional Commitment In Montana, John Carr
Judicial Independence As A Constitutional Commitment In Montana, John Carr
Montana Law Review
No abstract provided.
The End Of Peremptory Strikes?: Free Exercise And Religion-Based Batson Challenges, Jeremy Ross
The End Of Peremptory Strikes?: Free Exercise And Religion-Based Batson Challenges, Jeremy Ross
Montana Law Review
No abstract provided.
Montana Kaimin, March 5, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, March 5, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, 1898-present
Student newspaper of the University of Montana, Missoula.
Using Facial Landmarks For Lip Motion Interpretation Applications, Kimi S. Wright
Using Facial Landmarks For Lip Motion Interpretation Applications, Kimi S. Wright
Theses and Dissertations
Facial motion, particularly lip movement, carries rich information about human speech that can be leveraged for a variety of computer vision and speech-processing tasks. Unlike other pixel-based methods, this work investigates the use of facial landmarks as a compact, privacy- preserving, and computationally efficient representation for lip-motion analysis. We evaluate landmark-based models across multiple tasks, including visual voice activity detection (VVAD), lip–audio synchroniza- tion, and visual speech recognition (VSR) for liveness detection. Using LRS3-VVAD1 and LRS22 datasets, we demonstrate that landmark-only models can achieve performance comparable to pixel-based systems for VVAD and synchronization, while significantly reducing parameter counts and inference …
March 5, 2026, The Daily Mississippian
March 5, 2026, The Daily Mississippian
Daily Mississippian (all digitized issues)
No abstract provided.
The Physiology, Pathophysiology, And Clinical Implications Of Fluid Resuscitation In Critically Ill Patients, Akram M. Eraky, Yasser Mokhtar, Adnan Khan, Amr Farag, Sondos Elawany, Walaa Alsabbagh, Alisha Wright, Mostafa Alamrosy
The Physiology, Pathophysiology, And Clinical Implications Of Fluid Resuscitation In Critically Ill Patients, Akram M. Eraky, Yasser Mokhtar, Adnan Khan, Amr Farag, Sondos Elawany, Walaa Alsabbagh, Alisha Wright, Mostafa Alamrosy
GME Publications
One of the most common interventions in the ED and ICU to restore physiologic homeostasis is fluid administration. It is essential for the intensivists and ED physicians to be aware of the physiological characteristics of different fluids and the potential harm associated with their use. In this article, we explore the physiology and pathophysiology of fluid administration in humans, emphasizing how fluid administration can alter acid-base balance, perfusion, osmotic and oncotic pressures, immunologic and inflammatory responses, and hemodynamics. We also discuss fluid resuscitation strategies across common clinical scenarios, such as septic shock, diabetic ketoacidosis, rhabdomyolysis, acute pancreatitis, and acute brain …
Bi-Allelic Variants In Nrdc Cause A Neurodevelopmental Disorder Characterized By Neonatal Lethality, Microcephaly, And Brain Abnormalities, Davut Pehlivan, Abigail Sandoval, Reza Maroofian, François Lecoquierre, Aisha M Al Shamsi, Gyu S Lee, Osman Yesilbas, Preston Taylor, Matthew B Mcdougal, Vahid Bahrambeigi, Omid Aryani, Juan Felipe Ramirez, Khalid Hama Salih, Chadi Al Alam, Heba Morsy, Haytham Hussien, Tarek Omar, Ibrahim M Abdelrazek, Anne Claire Brehin, Dana Marafi, Tugba Kalayci, Jubran Abu Rahma, Jawabreh Kassem Talbeya, Husein Dabbah, Eric Verspyck, Toktam Moosavian, Jawid M Fatih, Tadahiro Mitani, Gulsen Akay, Daniel G Calame, Anne-Marie Guerrot, Wendy K Chung, Henry Houlden, James R Lupski, Adel Shalata, Wan Hee Yoon
Bi-Allelic Variants In Nrdc Cause A Neurodevelopmental Disorder Characterized By Neonatal Lethality, Microcephaly, And Brain Abnormalities, Davut Pehlivan, Abigail Sandoval, Reza Maroofian, François Lecoquierre, Aisha M Al Shamsi, Gyu S Lee, Osman Yesilbas, Preston Taylor, Matthew B Mcdougal, Vahid Bahrambeigi, Omid Aryani, Juan Felipe Ramirez, Khalid Hama Salih, Chadi Al Alam, Heba Morsy, Haytham Hussien, Tarek Omar, Ibrahim M Abdelrazek, Anne Claire Brehin, Dana Marafi, Tugba Kalayci, Jubran Abu Rahma, Jawabreh Kassem Talbeya, Husein Dabbah, Eric Verspyck, Toktam Moosavian, Jawid M Fatih, Tadahiro Mitani, Gulsen Akay, Daniel G Calame, Anne-Marie Guerrot, Wendy K Chung, Henry Houlden, James R Lupski, Adel Shalata, Wan Hee Yoon
Faculty, Staff and Students Publications
Nardilysin (NRDC) plays a role in multiple cellular functions in diverse cellular compartments, including ectodomain shedding in the plasma membrane, as well as chaperoning a key Krebs cycle enzyme in mitochondria. We had previously reported limited clinical information from two individuals with homozygous frameshift variants in NRDC. With inclusion of previously published individuals, here we report 14 individuals (10 females, four males) from nine unrelated families carrying homozygous NRDC pathogenic variants. Common clinical features include severe to profound developmental delay/intellectual disability (12/12), microcephaly (13/13), prematurity (5/13), lethality in the first 3 years of life (9/14), seizures (7/11), joint contractures (4/8), …
Computational Discovery Of Sars-Cov-2 Viral Entry Inhibitory Peptides From Androctonus Mauretanicus Scorpion Venom: Molecular Docking And Molecular Dynamics Simulations Targeting The Spike Protein, Reda Chahir, Salaheddine Redouane, Jacob Galan, Hicham Hboub, Lahoussaine Aserrar, Salma Chakir, Ahmed Salim Lahlou, Hinde Aassila, Rachid El Fatimy, Naoual Oukkache
Computational Discovery Of Sars-Cov-2 Viral Entry Inhibitory Peptides From Androctonus Mauretanicus Scorpion Venom: Molecular Docking And Molecular Dynamics Simulations Targeting The Spike Protein, Reda Chahir, Salaheddine Redouane, Jacob Galan, Hicham Hboub, Lahoussaine Aserrar, Salma Chakir, Ahmed Salim Lahlou, Hinde Aassila, Rachid El Fatimy, Naoual Oukkache
School of Medicine Publications
Background and Objective:
While vaccination remains central to controlling the COVID-19 pandemic, the emergence of SARS-CoV-2 variants with partial resistance to immune responses has highlighted the need for complementary therapeutic strategies. Among these, antiviral agents that inhibit viral entry mechanisms are of particular interest. Animal venoms, especially scorpion venoms, are a rich source of bioactive peptides with potential antiviral properties. This study aimed to evaluate peptides derived from the Moroccan scorpion Androctonus mauretanicus as inhibitors of SARS-CoV-2 spike glycoprotein, which mediates virus entry into host cells via ACE2 receptor binding.
Material and Methodology:
Six peptides from the venom of the …
Tidal Modulation Of Topographic Eddies Drives Marine Megafauna Aggregations, Harvey Cairns, Daniel Conley, Philip Hosegood, Christopher Stokes
Tidal Modulation Of Topographic Eddies Drives Marine Megafauna Aggregations, Harvey Cairns, Daniel Conley, Philip Hosegood, Christopher Stokes
School of Biological and Marine Sciences
Hanifaru Bay, in Baa Atoll, Maldives, is globally recognised for hosting the largest known feeding aggregations of reef manta rays (Mobula alfredi). These aggregations are spatially and temporally discrete, often associated with flood tides, and are thought to result from hydrodynamic processes that elevate zooplankton concentrations. This study investigates the role of flow-topography interactions, specifically around the small headland-like feature in the bay’s inlet (the ‘nodule’), in creating conditions conducive to these feeding events.A Delft3D hydrodynamic model of Baa Atoll was developed to simulate tidal flows within the bay, with high-resolution mesh focusing on Hanifaru Bay. Calibration and validation against …
Global Evidence For The Ecological Effects Of Greening Of Grey Infrastructure: A Systematic Review Protocol, Jessica R. Allen, Louise B. Firth, Melanie J. Bishop, Katherine A. Dafforn, Ferrante Grasselli, Mick E. Hanley, Antony M. Knights, Mariana Mayer-Pinto, Abigail Mcquatters-Gollop, Kathryn A. O’Shaughnessy, Francesca Porri, Rebecca K. Smith, Elisabeth M.A. Strain, Anaëlle J. Lemasson
Global Evidence For The Ecological Effects Of Greening Of Grey Infrastructure: A Systematic Review Protocol, Jessica R. Allen, Louise B. Firth, Melanie J. Bishop, Katherine A. Dafforn, Ferrante Grasselli, Mick E. Hanley, Antony M. Knights, Mariana Mayer-Pinto, Abigail Mcquatters-Gollop, Kathryn A. O’Shaughnessy, Francesca Porri, Rebecca K. Smith, Elisabeth M.A. Strain, Anaëlle J. Lemasson
School of Biological and Marine Sciences
BackgroundThe presence of artificial structures in our marine environments is increasing rapidly, with negative impacts for biodiversity. Greening of grey infrastructure (GGI) - an eco-engineering method applied to the marine context - aims to increase the ecological value of traditional grey infrastructure, while still allowing it to perform its primary human-centric function. GGI is a rapidly increasing field of research, being tested and implemented worldwide by academics, private practitioners, governments, non-governmental organisations (NGOs), amongst others, using a variety of methods. Outcomes vary widely, and results are communicated across a range of peer-reviewed and grey literature, rendering the evidence base for …
Brd4-Mediated Er Membrane Contact Creates Functionally Distinct Mitochondrial Subtypes, Brandon Chen, Rachel M Guerra, David J Pagliarini, Et Al.
Brd4-Mediated Er Membrane Contact Creates Functionally Distinct Mitochondrial Subtypes, Brandon Chen, Rachel M Guerra, David J Pagliarini, Et Al.
2020-Current year OA Pubs
Inter-organellar communication is critical for cellular metabolism. One of the most abundant inter-organellar interactions occurs at the endoplasmic reticulum and mitochondria contact sites (ERMCSs). However, an understanding of the mechanisms governing ERMCS regulation and their roles in cellular metabolism is limited by a lack of tools that permit temporal induction and reversal. Through screening approaches, we identified fedratinib, an FDA-approved drug that dramatically increases ERMCS abundance by inhibiting the epigenetic modifier BRD4. Fedratinib rapidly and reversibly modulates mitochondrial and ER morphology, induces a distinct ER-mitochondria envelopment structure, and alters metabolic homeostasis. Moreover, ERMCS modulation depends on mitochondrial electron transport chain …
High School Teachers’ Perspectives Of Middle School Biomedical Science Career Exploration Programs, Stephanie Gurule-Leyba
High School Teachers’ Perspectives Of Middle School Biomedical Science Career Exploration Programs, Stephanie Gurule-Leyba
Walden Dissertations and Doctoral Studies
Biomedical sciences (BMS) are a common career pathway for U.S. Hispanic high school students interested in pursuing healthcare careers. Little was known about how middle school career exploration programs in science, technology, engineering, and mathematics motivate Hispanic students to continue pursuing BMS careers. The purpose of this basic qualitative study was to explore high school teachers’ perspectives of how middle school BMS career exploration programs can motivate Hispanic students’ interest in BMS careers. The study was grounded in Keller’s attention, relevance, confidence and satisfaction motivation model. Thirteen high school BMS teachers, who have taught or are currently teaching the PLTW …
A.Actinomycetemcomitans Adhesi Protein Increasing Il-8 Titre In Heart Of Wistar Rat With Aggressive Periodontitis (Protein Adhesin Dari A.Actinomycetemcomitans Meningkatkantiter Il -8 Di Dalamjantungtikuswistar Denganperiodontitis Agresif), Rini Devijanti Ridwan, Retno Indrawati
A.Actinomycetemcomitans Adhesi Protein Increasing Il-8 Titre In Heart Of Wistar Rat With Aggressive Periodontitis (Protein Adhesin Dari A.Actinomycetemcomitans Meningkatkantiter Il -8 Di Dalamjantungtikuswistar Denganperiodontitis Agresif), Rini Devijanti Ridwan, Retno Indrawati
Dentofasial
Cardiovascular and periodontal diseases are common inflammatory conditions in the human population. Tlymphocytes
participate
in
the
pathogenesis and inflammatory events of atherosclerosis. These immune cells enter the
inflamed artery wall and join macrophages via a number of interferon-c-inducible chemokines. Chemokines (IL-8),
cytokines, and growth factors also participate in this process. The interaction between interleukin- 8 and its receptor,
CXCR2, can also contribute to lesion formation in mice. The main causes of aggressive periodontitis is
Actinobacillus
actinomycetemcomitans
. Previous studies have proven that adhesin protein with 24 kDa molecular weight from
A.actinomycetemcomitans is a specific adhesin, this adhesin proteins play a …
Saliva Buatan Meningkatkan Kekuatan Tekan Semen Ionomer Kaca Tipe Ii Yang Direndam Dalam Minuman Isotonik (Artificial Saliva Increases The Compressive Strength Of Glass Ionomer Cement Type Ii Soaked In Isotonic Drinks), Juliatri Juliatri, D.H.C. Pangemanan, Dwi Cahya Fitriyana
Saliva Buatan Meningkatkan Kekuatan Tekan Semen Ionomer Kaca Tipe Ii Yang Direndam Dalam Minuman Isotonik (Artificial Saliva Increases The Compressive Strength Of Glass Ionomer Cement Type Ii Soaked In Isotonic Drinks), Juliatri Juliatri, D.H.C. Pangemanan, Dwi Cahya Fitriyana
Dentofasial
Immersion of glass ionomer cement (GIC) type II in acid drink like isotonic drink could reduce its compressive strength.
This is due to the matrix degradation process of GIC in acid condition. However, there is artificial saliva that can
neutralize this condition. The purpose of this study was to evaluate the effect of artificial saliva on compressive strength
of glass ionomer cement type II immersed in isotonic drink. The GICspecimens of 6 x 6 x 12 mm
3
beam were immersed for
24 hours in distilled water, 24 hours in isotonic drink, 24 hours in isotonic drink continued with 72 …
Efek Pegagan (Centella Asiatica L)Terhadap Proliferasi Mesenchymal Stem Cell (Effect Of Pegagan (Centella Asiatica L)To Mesenchymal Stem Cell Proliferation), Ira Arundina, Ketut Suardita
Efek Pegagan (Centella Asiatica L)Terhadap Proliferasi Mesenchymal Stem Cell (Effect Of Pegagan (Centella Asiatica L)To Mesenchymal Stem Cell Proliferation), Ira Arundina, Ketut Suardita
Dentofasial
Stem cells provide new hope to fasten the healing process of various oral diseases including periodontal tissue
(periodontitis). At present time, there is not yet found a material that can fix the teeth perfectly. Adult stem cells from
bone marrow widely used for treatment. Numbers of stem cell are limited so growth factor is necessary to promote
proliferation of stem cells. Growth factor that has been used is expensive and difficult to get. Because of these
constraints, it is necessary to develop alternative uses of medicinal plants as growth factor that accelerates wound
healing process. This study is aimed to …
Sandwich Osteotomy For Vertical And Transversal Augmentation Of The Posteriormandible: A Review Sandwich Osteotomy Untuk Augmentasi Vertikal Dan Transversal Pada Posterior Mandibula: Sebuah Tinjauan, Sariatun Tawainela, Irma Drismayanti, A’La Unas B, Muh. Ruslin, Eri H. Jubhari
Sandwich Osteotomy For Vertical And Transversal Augmentation Of The Posteriormandible: A Review Sandwich Osteotomy Untuk Augmentasi Vertikal Dan Transversal Pada Posterior Mandibula: Sebuah Tinjauan, Sariatun Tawainela, Irma Drismayanti, A’La Unas B, Muh. Ruslin, Eri H. Jubhari
Dentofasial
The use of endosseous implants is directly related to the topography and quality of the patient’s residual bone. Several
techniques have been tried to expand its application through implant design alterations and surgical techniques for bone
augmentation. This article reviews the sandwich osteotomy combined with an interpositional autograft for vertical and
transversal augmentation in the atrophic mandible prior to endosseous implant placement. In conclusion, segmental
mandibular sandwich osteotomy can be recommended to fulfill the dimensional requirements of preimplant bone
augmentation in atrophic posterior mandible.
Perbandingan Tingkat Keberhasilan Implan Antara Osteogenesis Distraksi Dengan Autogenous Bone Graft Ratio Of Successful Rate Of Dental Implan Between Distraction Osteogenesis With Autogenous Bone Graft, Irma Drismayanti, Sariatun T, A’La Unas B, Muh. Ruslin, Eri H. Jubhari
Perbandingan Tingkat Keberhasilan Implan Antara Osteogenesis Distraksi Dengan Autogenous Bone Graft Ratio Of Successful Rate Of Dental Implan Between Distraction Osteogenesis With Autogenous Bone Graft, Irma Drismayanti, Sariatun T, A’La Unas B, Muh. Ruslin, Eri H. Jubhari
Dentofasial
Endosseous dental implants are the treatment of choice for restoring function and reconstructing most edentulous
areas of the maxilla and mandible. One of the most common problems in oral implantology is insufficient bone height
between the alveolar ridge and the mandible canal, as a result of mandibular atrophy from edentulism. Generally,
alveolar bone defects can be reconstructed by either distraction osteogenesis (DO)or autogenous bone grafting
(ABG). This paper discussed implant successful rate in DO versus ABG. DO shows a higher successful rate of implant
than ABG with the result more esthetic, lower rate of infection and bone resorption, no pain …
Sitotoksisitas Pemutih Gigi Berdasarkan Konsentrasi Bahan, Mardiana A. Adam, Asti Meizarini
Sitotoksisitas Pemutih Gigi Berdasarkan Konsentrasi Bahan, Mardiana A. Adam, Asti Meizarini
Dentofasial
The aim of this study was to evaluate the cytotoxicity of several tooth whitening material,
carbamide peroxide 10%, 15%, 20% and hydrogen peroxide 38% toward BHK-21 cell
using MTT assay. Each well of microplates which used for the test were aliquotted BHK21
cell suspension, after that the test solution were added to eight well each group,
respectively. The result showed that percentages of the living cell at 10% carbamide
peroxide group = 86,73%; 15% = 81,22%; 20% = 81,82%; 38% hidrogen peroksida =
64,08%, respectively. Anova test and LSD showed no significant difference between 10%,
15%, 20% groups, but there …
Perbandingan Sitotoksisitas Endomethasone, Ah Plus, Dan Apexit Plus Terhadap Sel Fibroblas Dengan Teknik Root Dipping, Christine A. Rovani, Kamizar Kamizar, Munyati Usman
Perbandingan Sitotoksisitas Endomethasone, Ah Plus, Dan Apexit Plus Terhadap Sel Fibroblas Dengan Teknik Root Dipping, Christine A. Rovani, Kamizar Kamizar, Munyati Usman
Dentofasial
The purpose of this study was to evaluate the lowest cytotoxicity of three endodontic
sealers, Apexit Plus, AH Plus and Endomethasone that can be used safely. The crown
of 30 intact lower premolars were removed at cementodentinal juntion and the teeth
were prepared with crown down technique with # 20 initial file and # 30 master
apical file. After sterilization, the 30 teeth were randomly divided into three groups
and filled with gutta percha using laterally condensation technique and Apexit Plus,
AH Plus, and Endomethasone as sealers. Apex of the roots was dipped 1.5 mm into
culture medium for 24 …
Teknik Penyajian Presentasi Ilmiah Yang Efektif Dengan Menggunakan Media Elektronik, Elizabeth Mailoa
Teknik Penyajian Presentasi Ilmiah Yang Efektif Dengan Menggunakan Media Elektronik, Elizabeth Mailoa
Dentofasial
The digital era has transformed the manner in which scientific material is presented
to dental professional. With recent technological advances, speakers presenting
information have greater options to deliver their materials. Most notably, speakers
are able to use media to assist and enhance presentations. Recent technology of
presentations with software such as PowerPoint has becoming popular lately, because
this software has many advantages, such as the ability to incorporate graphics, text
and sound in a multimedia files. An effective presentation is when your audience can
easily grasp the ideas you are trying to get across. In scientific presentations
engaging and clear …
Considerations Of Tooth Extraction During Pregnancy, M. Hendra Chandha
Considerations Of Tooth Extraction During Pregnancy, M. Hendra Chandha
Dentofasial
regnancy is a common sense. However, when dental care, is likely to perform in
particular tooth extraction, a dentist should be aware of any systemic changes occurred
during pregnancy that can lead to several problems in dental practice. This paper is aimed
to discuss the consideration of taking dental radiography and prescribing medicine for an
expectant mother that can't be avoided during oral surgery.
Jbs – Usa Silver Anniversary Conference Chicago, March 23-26, 2023 Thomas Club At Symphony Center
Jbs – Usa Silver Anniversary Conference Chicago, March 23-26, 2023 Thomas Club At Symphony Center
Journal of the Jussi Björling Societies of the USA & UK
The Board of Directors is delighted to announce registrations are now available for our 25th Anniversary Conference in Chicago. In addition to celebrating Jussi’s career, we will be adding extra activities and remembrances of 25 years of JBS-USA.
Numerals And Other Means Of Expressing Plurality In Language And Thought: A Developmental Perspective Across Cultures., Giovanni Giuseppe G.G. Nicosia Prof.
Numerals And Other Means Of Expressing Plurality In Language And Thought: A Developmental Perspective Across Cultures., Giovanni Giuseppe G.G. Nicosia Prof.
Numeracy
Several ancient languages use linguistic structures to differentiate between singular, dual, and plural forms that are used when one, two, or many objects are referenced. (Some languages go further, adding a trial form to differentiate two from three.) In many modern languages, numerals are used to convey precise number. After reviewing a range of ways languages express number (including the interesting case of Pirahã which does not express precise number), the paper concludes with a proposed developmental path for the expression of quantity in languages.
The Student Movement Volume 110 Issue 16: Running, Biking, And Swimming Into Women's History Month, Addison Randall, Ysa Dennis, Melanie Webb, Anna Pak, Esther R. Knott, Laura Pérez, Madison Vath, Corinna Bevier
The Student Movement Volume 110 Issue 16: Running, Biking, And Swimming Into Women's History Month, Addison Randall, Ysa Dennis, Melanie Webb, Anna Pak, Esther R. Knott, Laura Pérez, Madison Vath, Corinna Bevier
The Student Movement V. 110 (2025-2026)
ARTS & ENTERTAINMENT
Creativity and Talent on Display at the AU Composers Concert, Addison Randall
The Idea of Patrick Bateman: Yuppie Culture and Misinterpreting Films, Ysa Dennis
Bringing Home Full Numbers: A Review of AUTW's 'Much Ado About Nothing', Melanie Webb
HUMANS
Students Serving Through Their Studies, Anna Pak
NEWS
Administration Announces Endowed Chair for Stephen Zork, Addison Randall
IDEAS
'Until I Make My Brothers Understand...', Esther R. Knott
PULSE
Students Explore Relationships with Purpose at Makarios First Spanish Small Group Meeting, Laura Pérez
Senioritis Through a Temporal Context, Madison Vath
LAST WORD
The True Story of How 'National Treasure' …
Student Senate Meeting Minutes March 4, 2026, Student Senate-Winona State University
Student Senate Meeting Minutes March 4, 2026, Student Senate-Winona State University
Student Senate Meeting Minutes
This document is the official Winona State University Student Senate Minutes for March 4, 2026.
The Lumberjack, March 04, 2026
The Lumberjack, March 04, 2026
Cal Poly Humboldt's Student Newspaper
The student newspaper of Humboldt State University.
Young Fisher Completes Longest Recorded Journey To Find New Forest Home, Robbin Ray
Young Fisher Completes Longest Recorded Journey To Find New Forest Home, Robbin Ray
UNH Today Archive
No abstract provided.
The Medicinal Landscape Of Chrysanthemum Indicum L.: Bridging Traditional Wisdom And Modern Evidence, Gavin Liu, Elena Alexa, Tao Zhang
The Medicinal Landscape Of Chrysanthemum Indicum L.: Bridging Traditional Wisdom And Modern Evidence, Gavin Liu, Elena Alexa, Tao Zhang
Research Outputs: 2025-Present
Chrysanthemum indicum L. (C. indicum), a perennial herb widely distributed across East Asia,has long been utilised in traditional medicine and as a functional food ingredient. Contemporaryresearch has revealed a chemically diverse phytochemical profile, dominated byflavonoids, phenolic acids, sesquiterpene lactones, essential oils, carotenoids, and polysaccharides,which collectively underpin its broad pharmacological potential. Experimentalstudies demonstrate that extracts and isolated constituents of C. indicum exert pronouncedantioxidant, anti-inflammatory, antimicrobial, hepatoprotective, cardioprotective, and anticancereffects in vitro and in vivo, often through modulation of key molecular pathwayssuch as NF-κB, NLRP3 inflammasomes, AMPK–SIRT1, and Nrf2 signalling. Emergingpharmacokinetic evidence indicates variable oral bioavailability and metabolic transformationof major bioactive compounds, …