Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2026

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 8671 - 8700 of 14603

Full-Text Articles in Entire DC Network

Quantitative Analysis Of Thiamine, Riboflavin, And Niacin Vitamins By High-Performance Liquid Chromatography In Pharmaceutical Sample Tablets And Drops, Sarra A. Abrahem, Suhad A. Ibrahim, Alaa Sh. Abdulbari, Noor M. Ali, Maryam Y. Hashim Mar 2026

Quantitative Analysis Of Thiamine, Riboflavin, And Niacin Vitamins By High-Performance Liquid Chromatography In Pharmaceutical Sample Tablets And Drops, Sarra A. Abrahem, Suhad A. Ibrahim, Alaa Sh. Abdulbari, Noor M. Ali, Maryam Y. Hashim

Baghdad Science Journal

Levering cutting-edge high-performance liquid chromatography techniques with a C-18 column, we meticulously crafted a gradient of MeOH and glacial CH3COOH (96–5%), pulsating through at a mesmerizing 1.2 ml/min. With ultraviolet detection at a precise wavelength of 245 nm, we unraveled the mysteries of these vital nutrients. Thiamine reveals itself at a retention time of 3.5 min, followed by Riboflavin at 8.1 min and Niacin at 10.8 min. The findings of this study were not just a spectacle of scientific powers but were also rigorously benchmarked against commercial drugs, ensuring accuracy and reliability in our analysis.


Studying The Level Of Amyloid-A And Fibrinogen-Like Protein 1 And Other Biomarkers In The Sera Of Rheumatoid Arthritis Of Iraqi Patients, Aya Waleed Aziz, Bushra Faris Hasan Mar 2026

Studying The Level Of Amyloid-A And Fibrinogen-Like Protein 1 And Other Biomarkers In The Sera Of Rheumatoid Arthritis Of Iraqi Patients, Aya Waleed Aziz, Bushra Faris Hasan

Baghdad Science Journal

Rheumatoid arthritis (RA) isa common chronic autoimmune disease characterized by synovitis causing pain and inflammation and can result in joint destruction, its risk factors involve a family history of disease, obesity, smoking as well as viral infections. In this study, serum amyloid A and fibrinogen-like protein 1 were evaluated in 80 patients and 40 healthy controls (both men and women). Measurement of SAA, FGL1, RF, CRP, and MPO were performed using ELISA kits, the colorimetric method has been employed for estimating lipid profile, and Westergren method has used to measure ESR. The results indicated that levels of SAA, FGL1, MPO, …


First Record Of Keratitis Caused By Valkampfia In Iraq, Turkan K. Karyagdi Mar 2026

First Record Of Keratitis Caused By Valkampfia In Iraq, Turkan K. Karyagdi

Baghdad Science Journal

Acanthamoeba is the most well-known causes amoebic keratitis. However, other free-living amoebas (FLA), such as Valkampfia, can also causes of keratitis. Twenty-two samples were collected from cases suspected of amoebic keratitis in Kirkuk Hospital to investigate the presence of Acanthamoeba . Cultivation process was carried out directly on non-nutrient agar (NNA) medium supported with killed Escherichia coli bacteria. Inverted and light microscope were used at 40X magnification to diagnose cultures growth .Only two samples showed positive growth on NNA medium. However, no any presence of Acanthamoeba was observed as were expected using polymerase chain reaction (PCR) which ampilified by …


Distribution Of Some Antibiotic Resistance Genes Among Carbapenem-Resistant Acinetobacter Baumannii Isolated From Patients Lying Icu In Al-Najaf /Iraq, Ghufran Rajab Taher, Ahlam Kadhim Alyasseen Mar 2026

Distribution Of Some Antibiotic Resistance Genes Among Carbapenem-Resistant Acinetobacter Baumannii Isolated From Patients Lying Icu In Al-Najaf /Iraq, Ghufran Rajab Taher, Ahlam Kadhim Alyasseen

Baghdad Science Journal

Acinetobacter baumannii is a significant nosocomial pathogen, affecting immunocompromised and critically ill patients in intensive care units (ICUs). The emergence of carbapenem-resistant A. baumannii (CRAB) poses a threat due to its resistance to multiple antibiotics. This study investigates the prevalence of carbapenemase-encoding genes among CRAB isolates from ICU patients at AL-Sadder hospital/ Najaf. Eight sputum specimens were collected from ICU patients suspected of A. baumannii. The isolates were identified through morphological, biochemical tests and the Vitek 2 Compact system. Antibiotic sensitivity was determined by the Vitek 2 Compact system (using AST card). only 5 A. baumannii isolates have been …


Protective Effect Of Boswellia Carterii And Gum Arabic (Senegalia Senegal) On Induced Arthritic In Male Rats, Basma Ali Jasim, Alia Hussein Ali Mar 2026

Protective Effect Of Boswellia Carterii And Gum Arabic (Senegalia Senegal) On Induced Arthritic In Male Rats, Basma Ali Jasim, Alia Hussein Ali

Baghdad Science Journal

The study aims to use natural substances like Senegalia senegal and Boswellia carterii to treat rheumatoid arthritis, a painful disease affecting joints and making movement difficult, , The two plants were used to treat the symptoms of induced arthritis in male rats by using the complete freund's adjuvant method. A group of thirty adult male rats was used in this study, divided into six groups, with five rats for each group. The 1st group was the negative control (without arthritis induced and without treatment); the 2nd group is the positive control group (with arthritis induced and without any treatment); the …


Chicago Brass Band And Symphonic Winds: March 20, 2026, Dr. Mark Taylor, Dr. F. Mack Wood, Dr. Damon S. Talley, Madison Mueller-Howell Mar 2026

Chicago Brass Band And Symphonic Winds: March 20, 2026, Dr. Mark Taylor, Dr. F. Mack Wood, Dr. Damon S. Talley, Madison Mueller-Howell

School of Music Programs

This is the one hundred and twenty-first program of the 2025-2026 season.

Center for the performing Arts

March 20, 2026

Friday Evening

8:00 p.m.


Multi-Objective Optimization Of Waste Incineration For Minimal Carbon Monoxide And Sulfur Dioxide Emission And Rate Maximization: A Case Study Of Mbezi, Mkuranga-Pwani, Tanzania, Grangay M. Nyanghura, Enock W. Nshama Mar 2026

Multi-Objective Optimization Of Waste Incineration For Minimal Carbon Monoxide And Sulfur Dioxide Emission And Rate Maximization: A Case Study Of Mbezi, Mkuranga-Pwani, Tanzania, Grangay M. Nyanghura, Enock W. Nshama

Tanzania Journal of Science

Incineration is widely employed for hazardous waste disposal, but results in harmful flue gas emissions. This study optimizes a double-chamber incineration process to reduce sulfur dioxide (SO2) and carbon monoxide (CO) emissions while maximizing the incineration rate. The effects of waste mass, primary chamber temperature (PT), and secondary chamber temperature (ST) were analyzed using a full factorial design of 27 experiments. ANOVA revealed that mass had the greatest impact on emissions and incineration time, ST had a moderate effect, and PT had little influence. Regression analysis provided models for incineration time, CO, and SO2 emissions. Single-objective optimization using sequential quadratic …


Honey Bees (Apis Mellifera) Pollination Enhances Watermelon (Citrullus Lanatus) Yield In Kibaha Tanzania, Beatrice Tonola, Charles Olambo Joseph, Mkabwa L.K. Manoko, Shibonage K. Mashilingi Mar 2026

Honey Bees (Apis Mellifera) Pollination Enhances Watermelon (Citrullus Lanatus) Yield In Kibaha Tanzania, Beatrice Tonola, Charles Olambo Joseph, Mkabwa L.K. Manoko, Shibonage K. Mashilingi

Tanzania Journal of Science

Honey bees are essential pollinators of the world’s food crops. However, information on the influence of honey bee pollination on watermelon yield is limited in Tanzania. This study assessed efficiency of honey bee pollination on watermelon yield. The study tested three improved watermelon varieties (Zebra F1, Candy F1 and Sukari F1) and three pollination environments: (Caged with Apis mellifera (CAM), Caged without insects (CW) and Open pollination (OP) in two seasons. The experiment was arranged in a split-plot design in randomized complete block design (RCBD) with three replications. Results showed no significant interaction between pollination environment and varieties. Significant difference …


Performance Forum - March 20, 2026, Mia Cotton, Sheng Yuan Kuan, Virgilio Vazquez, Dj Combs, Ay Kawasaki, Yilian Concepcion, Jon Cruz, Aidan Quintana Mar 2026

Performance Forum - March 20, 2026, Mia Cotton, Sheng Yuan Kuan, Virgilio Vazquez, Dj Combs, Ay Kawasaki, Yilian Concepcion, Jon Cruz, Aidan Quintana

Performance Forum

No abstract provided.


Antibacterial Activity Of Sapium Ellipticum, Securidaca Longepedunculata, And Allophylus Africanus Against Drug-Resistant Pseudomonas Aeruginosa Isolates, Eleonora A. Mbare, Rose J. Masalu, Cyprian B. Mpinda Mar 2026

Antibacterial Activity Of Sapium Ellipticum, Securidaca Longepedunculata, And Allophylus Africanus Against Drug-Resistant Pseudomonas Aeruginosa Isolates, Eleonora A. Mbare, Rose J. Masalu, Cyprian B. Mpinda

Tanzania Journal of Science

Pseudomonas aeruginosa poses a major clinical challenge due to its high levels of antibiotic resistance. This study evaluated the antibacterial activity of three medicinal plant extracts Allophylus africanus (leaves), Securidaca longepedunculata (root bark), and Sapium ellipticum (stem bark), against 30 drug-resistant P. aeruginosa isolates. Antibacterial screening was conducted using the agar well diffusion method, followed by determination of minimum inhibitory concentrations (MICs) via a 96-well microtiter plate assay. All three plant extracts demonstrated inhibitory activity against three resistant P. aeruginosa strains (gentamicin-resistant strains F4 and GR4RAU-AI, and ceftazidime-resistant strain 19-10), with inhibition zones of varying diameters. MIC values showed strain-specific …


Science Challenges And Solutions To Support Implementation Of The Biodiversity Beyond National Jurisdiction Agreement, Claire L. Szostek, Angus Atkinson, Victor Martinez-Vicente, Ana M. Queirós, Peter I. Miller, Kerry L. Howell, Rebecca C. Millington, Susan Kay, Matthew Faith, Karen Tait, Elizabeth Talbot, Andrew Rees, Chris Lyal, Jeff Ardron, Matthew Frost Mar 2026

Science Challenges And Solutions To Support Implementation Of The Biodiversity Beyond National Jurisdiction Agreement, Claire L. Szostek, Angus Atkinson, Victor Martinez-Vicente, Ana M. Queirós, Peter I. Miller, Kerry L. Howell, Rebecca C. Millington, Susan Kay, Matthew Faith, Karen Tait, Elizabeth Talbot, Andrew Rees, Chris Lyal, Jeff Ardron, Matthew Frost

School of Biological and Marine Sciences

The Biodiversity Beyond National Jurisdiction (BBNJ) Agreement provides a new opportunity to consolidate and achieve global marine environmental goals. Here we focus on how science and technology will support its implementation. We provide an overview of existing scientific knowledge and methods that are scalable to Areas Beyond National Jurisdiction (ABNJ). Reviewing data gaps, challenges and opportunities, we outline solutions and a roadmap focused on enhancing resources and capacity.


Plant-Based Dietary Patterns Are Associated With Slower Epigenetic Aging, Hyunju Kim, Christina A Castellani, Jiantao Ma, Alexis C Wood, Audrey Ting, Morgan E Grams, Bing Yu, Kelly Ruggles, James S Floyd, Dan E Arking, Casey M Rebholz Mar 2026

Plant-Based Dietary Patterns Are Associated With Slower Epigenetic Aging, Hyunju Kim, Christina A Castellani, Jiantao Ma, Alexis C Wood, Audrey Ting, Morgan E Grams, Bing Yu, Kelly Ruggles, James S Floyd, Dan E Arking, Casey M Rebholz

Faculty, Staff and Students Publications

Greater adherence to plant-based diets is associated with health benefits. Dietary intake can modify DNA methylation patterns, but it is unknown whether plant-based diets in a largely non-vegetarian population are associated with DNA methylation-based epigenetic aging measures. We examined the associations between 4 different types of plant-based diets indices (PDI) [overall PDI, provegetarian diet, healthy PDI, and unhealthy PDI] and epigenetic aging. We used data from the Atherosclerosis Risk in Communities (ARIC) Study (N=2,810) and National Health and Nutrition Examination Survey (NHANES, N=2,056). PDIs negatively scored higher intake of animal products and positively scored higher intake of all or selected …


Volume 60-1 Full Issue, Ryan Brown Mar 2026

Volume 60-1 Full Issue, Ryan Brown

Journal of STEM Teacher Education

No abstract provided.


“I’M So Hungry”: Assessing Stem Sensemaking Through Data-Informed Writing, Bailey Nafziger, Alesia Mickle Moldavan, Katie Brkich Mar 2026

“I’M So Hungry”: Assessing Stem Sensemaking Through Data-Informed Writing, Bailey Nafziger, Alesia Mickle Moldavan, Katie Brkich

Journal of STEM Teacher Education

To engage elementary learners in the complex task of STEM sensemaking, teachers must entice and inspire learners to ask questions, explore, and communicate their findings. This article shares a 5E/3D lesson designed and taught in our elementary science methods courses to model how preservice teachers can integrate literacy and mathematics into a science investigation for STEM sensemaking. We modified a traditional lesson on bird beak adaptations to have a differentiated, interdisciplinary writing component justified by data. We discuss why data-supported literacy is a non-negotiable in science education reforms and how teachers can differentiate tasks to make scientific writing more approachable …


Who Feeds On Whom? Identifying Ticks Feeding On Mammal, Brenna G. Albright, Christina Espada, Mykenna Zettle, Abbey Jones, David T. Gauthier, Holly Gaff Mar 2026

Who Feeds On Whom? Identifying Ticks Feeding On Mammal, Brenna G. Albright, Christina Espada, Mykenna Zettle, Abbey Jones, David T. Gauthier, Holly Gaff

Knowledge and Creativity Expo

Study of tick-host association is critical to understanding host-pathogen ecology. Collection of ticks from mammalian hosts is difficult because of permitting, cost, and time considerations, particularly for medium and large mammals. The ODU Tick Research Team has been collecting ticks from mammals since 2010 using a combination of serendipitous sampling from roadkill and donations from veterinarians, hunters, and wildlife rehabilitators. In this work, we quantify the association between Ixodes scapularis and Ixodes keiransi and various mammalian hosts in Virginia. Ixodes scapularis (deer tick or blacklegged tick) is the primary vector of the Lyme disease bacterium (Borrelia burgdorferi s.s.) in …


Targeting Hypothalamic Oxidative Stress And Neuroinflammation: A Novel Neuroprotective Role For Annona Muricata Seed Extract In Aluminium- Induced Alzheimer-Like Neurodegeneration, O. A Bamgbose, O. D Akanji, P. B Fakunle, D. O Taiwo-Ola, K. O Odubela, E. O Olayemi, B. A Akanbi, B. M David Mar 2026

Targeting Hypothalamic Oxidative Stress And Neuroinflammation: A Novel Neuroprotective Role For Annona Muricata Seed Extract In Aluminium- Induced Alzheimer-Like Neurodegeneration, O. A Bamgbose, O. D Akanji, P. B Fakunle, D. O Taiwo-Ola, K. O Odubela, E. O Olayemi, B. A Akanbi, B. M David

AUIQ Complementary Biological System

Alzheimer's disease (AD) is increasingly recognized as a multisystem neurodegenerative disorder involving oxidative stress and neuroinflammation beyond classical hippocampal pathology. The hypothalamus, a key regulator of metabolic and neuroendocrine homeostasis, remains comparatively underexplored in experimental AD models. This study investigated the effects of aqueous Annona muricata seed extract (SSE) on hypothalamic oxidative injury in an aluminium chloride (AlCl3)-induced Alzheimer's disease–like model in Wistar rats. Adult Wistar rats of both sexes were randomly assigned to five groups (n = 5): control, AlCl3 (100 mg/kg), SSE alone (200 mg/kg), AlCl3 + SSE, and AlCl3 + donepezil (10 …


Issue 482 March 19-April 2, 2026, The Local Voice Mar 2026

Issue 482 March 19-April 2, 2026, The Local Voice

The Local Voice

Featured Articles: "ZZ Top Brings The Big One! to Ole Miss’ Backyard."; "Aimee Nezhukumatathil’s Night Owl Illuminates the Dark. Off Square Books to host book launch for Night Owl on Tuesday, March 24 at 5:30 pm."; "The View Beyond The Balcony: “Conversation” with a Pop-Up."


Voice And Pain: Representations Of Disability In Adaptations Of “The Little Mermaid”, Ace Molloy Mar 2026

Voice And Pain: Representations Of Disability In Adaptations Of “The Little Mermaid”, Ace Molloy

Departmental Honors & Graduate Capstone Projects

Hans Christian Andersen’s 1837 story, “The Little Mermaid,” is a popular fairy tale that has been adapted several times by writers, filmmakers, and game developers. It is one of the few fairy tales with explicit portrayals of disability; the mermaid in the tale is nonspeaking and experiences chronic pain, as well as being a mermaid—a nonnormative figure who is aligned with disability. This paper looks at the ways that the mermaid is portrayed in literary, film, and new media adaptations from a disability-justice perspective. Examining multiple representations of the character, I argue that while feminist adaptations erase her disability and …


The Indiana Statesman, March 19, 2026, Indiana State University Mar 2026

The Indiana Statesman, March 19, 2026, Indiana State University

Student Newspaper

Education Extravaganza Connects Indiana State Students with K-12 Employers; Terre Haute police officers unite for the Special Olympics


Of Epistemes And Insects: How Drosophila And Butterflies Shape Our Understanding Of Radiation Risk, Donna M. Goldstein, Magdalena E. Stawkoski Mar 2026

Of Epistemes And Insects: How Drosophila And Butterflies Shape Our Understanding Of Radiation Risk, Donna M. Goldstein, Magdalena E. Stawkoski

Faculty Publications

This paper explores the complexities of extrapolating insect data to understand nuclear exposure effects on humans. Within radiation research, animal studies are invaluable tools for understanding biological effects of radiation exposure. However, data are often employed selectively, exposing unsettled science in extrapolating animal data to human radiation effects. Here we focus on our understanding of the genetic effects of radiation exposure, and how the debates about the long-term effects on humans were molded by research carried out on the model organism known as Drosophila; disagreements among scientists occurred within the constraints of research on this model organism, creating what …


A Day At Lillie Valley Farm Using Ai To Develop A Children's Picture Book's Visual World, Lisa Nicholas Mar 2026

A Day At Lillie Valley Farm Using Ai To Develop A Children's Picture Book's Visual World, Lisa Nicholas

AI Day 2026

Early-stage picture book development often requires extensive manual visual iteration to establish tone, style, and character cohesion. This project explores how AI-assisted illustration tools can streamline that exploratory phase while preserving artistic authorship. Lillie Valley Farm serves as a case study in blending human storytelling with AI-generated visual prototyping, following Bonnie and Farmer Sid in a warm farm setting. The human characters are intentionally illustrated only from behind, creating an immersive "reader-as-character" experience for young audiences.


Coping With Climate Change: A Mixed-Methods Approach To Understanding Irrigation Technology Outcomes In Gujarat, India, Jamie M. Sommer, Trupti Jain, Biplabketan Paul, Karina Yager, Eliza White, Andrew Hargrove, Peggy Ann Spitzer Mar 2026

Coping With Climate Change: A Mixed-Methods Approach To Understanding Irrigation Technology Outcomes In Gujarat, India, Jamie M. Sommer, Trupti Jain, Biplabketan Paul, Karina Yager, Eliza White, Andrew Hargrove, Peggy Ann Spitzer

Montclair State University Scholarship & Creative Works

Previous research on climate change interventions highlights that adaptation and mitigation strategies must be tailored to local contexts to effectively benefit both people and the environment. However, there remains a gap in analyzing the effectiveness of locally specific climate-related technologies in enhancing food security, improving livelihoods, and addressing social dimensions such as women’s autonomy. The authors address that gap by drawing on two data sources, one quantitative and one qualitative, to evaluate the impact of an irrigation technology. Specifically, the authors assess its effectiveness in improving crop yields and addressing issues related to migration, women’s autonomy, and economic conditions. The …


David Hice V. Eqt Corp Mar 2026

David Hice V. Eqt Corp

2026 Decisions

USDC for the Western District of Pennsylvania


Targeting Cardiomyocyte-Derived Extracellular Vesicle Mir-574-5p Protects Against Cognitive Impairment Induced By Ischemia-Reperfusion, Erya Chen, Xiaoyu Zhu, Haiqing Chang, Qi Li, Zhenkun Zhao, Changteng Zhang, Yu Cao, Yajing Wang, Xinliang Ma, Tao Zhu, Shu Zhang, Lu Gan, Jin Liu, Chan Chen Mar 2026

Targeting Cardiomyocyte-Derived Extracellular Vesicle Mir-574-5p Protects Against Cognitive Impairment Induced By Ischemia-Reperfusion, Erya Chen, Xiaoyu Zhu, Haiqing Chang, Qi Li, Zhenkun Zhao, Changteng Zhang, Yu Cao, Yajing Wang, Xinliang Ma, Tao Zhu, Shu Zhang, Lu Gan, Jin Liu, Chan Chen

Department of Emergency Medicine Faculty Papers

BACKGROUND:  Acute myocardial ischemia/reperfusion (MI/R) increases risk for cognitive decline, yet the underlying mechanisms mediating heart-brain communication remain poorly understood. Small extracellular vesicles (sEVs) have emerged as novel long-range signaling mediators and may play a critical role.

METHODS: MI/R was induced by transient ligation of the left anterior descending artery. Cognitive performance was assessed using multiple behavioral tests. sEVs derived from cardiomyocytes were labeled to track their distribution and cellular uptake in the brain. Heart and brain tissues were analyzed for microRNAs (miRNAs) expression using bioinformatics, qPCR, and RNAScope. The role of specific miRNAs was investigated through genetic inhibition of …


Fibrinogen-Bmal1 Signaling As A Therapeutic Target To Limit Aortic Dissection By Preserving Vsmc Contractility, Xiaohan Zhong, Dongjie Li, Yuanfei Zhao, Lu Dai, Jinzhang Li, Zhiqi Ji, Bojing Zuo, Hongshan Liu, Haixia Huang, Wei Wang, Haiyang Li, Yuyong Liu, Ming Gong, Xin-Liang Ma, Wenjian Jiang, Meili Wang, Hongjia Zhang Mar 2026

Fibrinogen-Bmal1 Signaling As A Therapeutic Target To Limit Aortic Dissection By Preserving Vsmc Contractility, Xiaohan Zhong, Dongjie Li, Yuanfei Zhao, Lu Dai, Jinzhang Li, Zhiqi Ji, Bojing Zuo, Hongshan Liu, Haixia Huang, Wei Wang, Haiyang Li, Yuyong Liu, Ming Gong, Xin-Liang Ma, Wenjian Jiang, Meili Wang, Hongjia Zhang

Department of Emergency Medicine Faculty Papers

Aortic dissection (AD) is a life-threatening vascular disease with a high mortality rate. Surgery is essential in the acute phase but carries significant risks, whereas elective surgery during the chronic phase yields better outcomes. However, no pharmacological therapy has been proven effective in slowing AD progression. In our recent pilot clinical study, an association between higher plasma fibrinogen levels and improved clinical outcomes was observed in AD patients, suggesting a potential protective role of fibrinogen. However, direct evidence supporting this hypothesis is lacking. In this study, a population-based analysis of nonsurgically managed patients with acute AD revealed a distinct association: …


Audubon Society Minutes, W.A. Ginham Mar 2026

Audubon Society Minutes, W.A. Ginham

Documents

Minutes of the Audubon Society--October 7, 1931, in Wesleyan Hall. The second part of the meeting was noted on November 4, 1931.


The Cowl - V. 89 N. 16 - March 19, 2026 Mar 2026

The Cowl - V. 89 N. 16 - March 19, 2026

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 16 - March 19, 2026. 16 pages.


Immunoregulatory Effects Of Choerospondias Axillaris (Roxb.) B.L.Burtt & A.W.Hill Fruit Extract In Mice With Insights On In Vitro Mechanism, Ravi Gautam, Anju Maharjan, Jaehee Lee, Sujeong Yang, Jihun Jo, Manju Acharya, Daeun Lee, Narayan Prasad Ghimire, Saroj Lamichhane, Byungsun Min, Changyul Kim, Hyoungah Kim, Yong Heo Mar 2026

Immunoregulatory Effects Of Choerospondias Axillaris (Roxb.) B.L.Burtt & A.W.Hill Fruit Extract In Mice With Insights On In Vitro Mechanism, Ravi Gautam, Anju Maharjan, Jaehee Lee, Sujeong Yang, Jihun Jo, Manju Acharya, Daeun Lee, Narayan Prasad Ghimire, Saroj Lamichhane, Byungsun Min, Changyul Kim, Hyoungah Kim, Yong Heo

Department of Microbiology and Immunology Faculty Papers

BACKGROUND: Lapsi (Choerospondias axillaris), a plant native to Nepal, has been traditionally used in Asian countries to treat cardiovascular conditions. However, its effects on immune regulatory function remain largely unexplored. This study aimed to in vivo evaluate the immunoregulatory properties of Lapsi fruit extract in mice on immunotoxic responses with analysis on in vitro mechanism for immune suppression, oxidative stress, and inflammatory response. Male Balb/c mice were intragastrically administered various doses of the extract for 21 days. In some mice, immune suppression was induced with cyclophosphamide, and subsequent immune recovery was assessed. In addition, RAW264.7 cells and THP-1-derived macrophages were …


Fire Scarring Does Not Significantly Impact Conifer Growth Response To Forest Fires In Utah, Connor B. Biser, Russell Torgersen, Otto Degroff, Steve Petersen Mar 2026

Fire Scarring Does Not Significantly Impact Conifer Growth Response To Forest Fires In Utah, Connor B. Biser, Russell Torgersen, Otto Degroff, Steve Petersen

Student Works

BYU Wildfire Symposium 2026 - First Place Research Application, People's Choice Award

Wildfires are an increasingly prevalent disturbance in forests in the western United States, and play an essential role in ecosystem function. Micro-variations in fire dynamics and intensity can leave individual trees with varying levels of damage. We hypothesized that trees with fire-scars would suffer a growth depression directly following the disturbance. Core samples were taken for dendrochronological analysis from 185 conifers at 29 points, representing 11 fires from 6 years. Our findings showed a growth depression in the first year following the fire, with no significant difference between …


Immunotherapy Of Tsa-1.C4 Or In Combination With Bnz Confers Protection Against Trypanosoma Cruzi Infection With A Distinct Cytokine Response, Landy Magaly Pech-Pisté, Victor Dzul-Huchim, Christian Florian Teh-Poot, Fabian Gusovsky, Kathryn Jones, Peter Hotez, Liliana Estefanía Villanueva-Lizama, Maria Elena Bottazzi, Jaime Ortega-Lopez, Julio Vladimir Cruz-Chan Mar 2026

Immunotherapy Of Tsa-1.C4 Or In Combination With Bnz Confers Protection Against Trypanosoma Cruzi Infection With A Distinct Cytokine Response, Landy Magaly Pech-Pisté, Victor Dzul-Huchim, Christian Florian Teh-Poot, Fabian Gusovsky, Kathryn Jones, Peter Hotez, Liliana Estefanía Villanueva-Lizama, Maria Elena Bottazzi, Jaime Ortega-Lopez, Julio Vladimir Cruz-Chan

Faculty, Staff and Students Publications

Chagas disease is a poverty-related neglected tropical disease caused by the protozoan Trypanosoma cruzi affecting approximately 6.3 million people, predominantly in the Americas. Approximately 30% of T. cruzi infections progress to chronic cardiomyopathy and 10% of these cases end in death from cardiac failure. The first-line drug Benznidazole (BNZ) require a prolonged treatment regimen and can be highly toxic. Here, we evaluate a therapeutic vaccine in T. cruzi-infected mice, based on the recombinant Trypomastigote Surface Antigen 1 (TSA-1.C4) protein and the emulsified adjuvant E6020, and in combination with a suboptimal dose of BNZ. We observed a reduced burden parasite in …