Digital Commons Network^™

Therapeutic Potential Of Bacillus Coagulans Unique Is2 Probiotic Supplementation On Early Periodontitis Patients: A Randomized Controlled Trial, Renu Gaur, Aysha Jebin A, Prabhuji M L V

International Arab Journal of Dentistry

Objectives: Bacillus coagulans (B. coagulans) is a probiotic commonly used for broad spectrum of systemic infections, its potential to treat oral infections, particularly periodontitis, is still being studied.The aim of the study was to evaluate the efficacy of probiotic B. coagulans as an adjunct to SRP in periodontitis patients.

Methods: Thirty systemically healthy patients with stage I/ stage II and grade A/ grade B periodontitis were selected and randomly divided into two groups. The control group received SRP along with placebo and the test group received SRP + B. coagulans probiotic chewable tablets. At baseline, one month, and three months …

Biologically Oriented Preparation Technique In Implant-Supported Fixed Prostheses: A Systematic Review, Ghida Lawand, Roudy Khayat, Yara Ismail, Maryse Nassif, Mahmood Dashti, Jimmy Londono, Rami Al Bahri, Hani Tohme

International Arab Journal of Dentistry

This systematic review was conducted to assess the clinical and esthetic outcomes associated with convergent collar implants and compare them to divergent collar implant. The review was registered on the PROSPERO register (registration number: CRD42022326338). The systematic literature search was conducted in accordance with PRISMA guidelines to identify studies on implant-supported prostheses related to the Biologically Oriented Preparation Technique (BOPT) until June 2023. Inclusion criteria involved experimental and clinical studies published in peer-reviewed journals, excluding expert opinions. Data extraction was performed, adhering to predefined parameters for BOPT, specifications of convergent collar implants, and the assessment of outcomes. The systematic review …

Balneotherapy For Sleep Improvement And Reducing Depression In Knee Osteoarthritis Patients, Anca Paula Ciurba, Alexandru Bogdan Ilieș, Ionel Haidu, Doriana Ioana Ciobanu, Theodora Ursu, Florin Mihai Marcu, Dorina Ianc

Baltic Journal of Health and Physical Activity

Background: Knee osteoarthritis (OA) is the most common chronic condition and a leading cause of global disability, often associated with pain, depression, and sleep disturbances. The purpose of this study was to investigate the effectiveness of warm mineral water combined with physical therapy on sleep quality, depression and pain intensity in patients with knee osteoarthritis. Materials and Methods: The study involved 101 subjects (68.78±6.92 years) who were assigned to  a control group (CG) or an experimental group (EG). All subjects benefited from physical therapy and electrotherapy for 10 days. The experimental group additionally benefited from therapy with hot mineral water. …

Screening For Food Insecurity In An Outpatient Ophthalmology Clinic: A Health Equity- Quality Improvement Fellowship Project, Christine Coward, Tricia Jacobson, Mahadevan Subramanian, Sharon Ojo, Theresa Green, Neil Seligman, Jan Schriefer

Journal of Academic Ophthalmology

Background: Various social determinants of health have been implicated in ophthalmic diseases, with food insecurity being particular important, given the link between food and conditions such as diabetic and hypertensive retinopathy. Although quality improvement initiatives that address food insecurity screening exist, data extending to the ophthalmic clinical setting is limited.

Purpose: We implemented a health equity quality improvement fellowship project to improve screening for food insecurity in an urban ophthalmology outpatient clinic that sees adults and children.

Methods: Several initiatives were implemented in an attempt to reach a goal of 80% of patients screened for food insecurity. …

Disgust Sensitivity And Orderliness, Ari Rad

SACAD: Scholarly Activities

This literature review serves as a map for understanding the relation between disgust sensitivity and trait orderliness, with a focus on a cybernetic framework to conceptualize the emotion of disgust as an evolutionary system. It adopts a systematic approach that begins with the evolutionary foundations and basic definitions of disgust as an emotion, trait orderliness, and, lastly, the process by which these traits could be pathologized. The pathologization is explained within the hypothesized cybernetic system (the Cybernetic Disgust-Orderliness Hypothesis) with the goal of demonstrating the interdependency of trait orderliness and the emotion of disgust. The body of research regarding the …

Mondo: Integrating Disease Terminology Across Communities., Nicole A Vasilevsky, Sabrina Toro, Nicolas Matentzoglu, Joseph E Flack, Kathleen R Mullen, Harshad Hegde, Sarah Gehrke, Patricia L Whetzel, Yousif Shwetar, Nomi L Harris, Mee S Ngu, Gioconda L Alyea, Megan S Kane, Paola Roncaglia, Eric Sid, Courtney L Thaxton, Valerie Wood, Roshini S Abraham, Maria Isabel Achatz, Pamela Ajuyah, Joanna S Amberger, Lawrence Babb, Jasmine Baker, James P Balhoff, Jonathan S Berg, Amol Bhalla, Xavier Bofill-De Ros, Ian R Braun, Eleanor C Broeren, Blake K Byer, Alicia B Byrne, Tiffany J Callahan, Leigh Carmody, Lauren E Chan, Amanda R Clause, Julie S Cohen, Marcello Deluca, Natalie T Deuitch, May Flowers, Jamie Fraser, Toyofumi Fujiwara, Vanessa Gitau, Jennifer L Goldstein, Dylan Gration, Tudor Groza, Benjamin M Gyori, William Hankey, Jason A Hilton, Daniel S Himmelstein, Stephanie S Hong, Charles T Hoyt, Robert Huether, Eric Hurwitz, Julius O B Jacobsen, Atsuo Kikuchi, Sebastian Köhler, Daniel R Korn, David Lagorce, Bryan J Laraway, Jane Y Li, Adriana J Malheiro, James Mclaughlin, Birgit H M Meldal, Shruthi Mohan, Sierra A T Moxon, Monica C Munoz-Torres, Tristan H Nelson, Frank W Nicholas, David Ochoa, Daniel Olson, Tudor I Oprea, Tomiko T Oskotsky, David Osumi-Sutherland, Kelley Paris, Helen E Parkinson, Zoë M Pendlington, Xiao P Peng, Amy Pizzino, Sharon E Plon, Bradford C Powell, Julie C Ratliff, Heidi L Rehm, Lyubov Remennik, Erin R Riggs, Sean Roberts, Peter N Robinson, Justyne E Ross, Kevin Schaper, Brian M Schilder, Johanna L Schmidt, Elliott W Sharp, Morgan N Similuk, Damian Smedley, Tam P Sneddon, Rachel Sparks, Ray Stefancsik, Gregory S Stupp, Shilpa Sundar, Terue Takatsuki, Imke Tammen, Kezang C Tshering, Deepak R Unni, Eloise Valasek, Adeline Vanderver, Alex H Wagner, Ryan F Webb, Danielle Welter, Doron Yaya-Stupp, Andreas Zankl, Xingmin Aaron Zhang, Julie A Mcmurry, Christopher G Chute, Ada Hamosh, Christopher J Mungall, Melissa A Haendel

Faculty Research 2026

Precision medicine aims to enhance diagnosis, treatment, and prognosis by integrating multimodal data at the point of care. However, challenges arise due to the vast number of diseases, differing methods of classification, and conflicting terminological coding systems and practices used to represent molecular definitions of disease. This lack of interoperability artificially constrains the potential for diagnosis, clinical decision support, care outcome analysis, as well as data linkage across research domains to support the development or repurposing of therapeutics. There is a clear and pressing need for a unified system for managing disease entities⁠-including identifiers, synonyms, and definitions. To address these …

Sex-Specific Differences In Lung Mitochondrial Function And Injury In Rats Exposed To Hyperoxia, Taheri Pardis, Abraham G. Taye, Devanshi D. Dave, Elizabeth R. Jacobs, Guru Prasad Sharma, Anne V. Clough, Ranjan K. Dash, Said H. Audi

Mathematical and Statistical Science Faculty Research and Publications

Hyperoxia is both an essential therapy and a contributor to lung injury in acute respiratory distress syndrome. We hypothesized that adult female rats are relatively protected from hyperoxia-induced acute lung injury (HALI) compared with males and that this protection is associated with sex-dependent differences in lung mitochondrial bioenergetics and H₂O₂ production. Adult rats were exposed to room air (normoxia) or hyperoxia (>95% O₂) for up to 60 h. Lung injury was assessed by pleural effusion, lung wet weight, pulmonary vascular filtration coefficient (K_f), histologic injury scores, and cleaved caspase-3 (CC3) staining. …

Morphology, Phylogeny And Distribution Of Scaeurgus (Cephalopoda: Octopoda) In Southeast Pacific Seamounts, Sergio A. Carrasco, Christian M. Ibáñez, Andrea I. Varela, Jan M. Tapia-Guerra, Erin E. Easton, Javier Sellanes

School of Earth, Environmental, & Marine Sciences Faculty Publications

Octopuses of the genus Scaeurgus inhabit upper bathyal benthic habitats and are composed of five recognized species. In this study, we conducted morphological and molecular phylogenetic analyses of two individuals of Scaeurgus and provided additional field observations of the genus in seamounts of the Nazca and Salas y Gómez ridges (southeast Pacific Ocean) over the last six years. Specifically, two specimens of Scaeurgus were collected at 234 m depth in 2019 during the EPIC oceanographic cruise onboard the R/V Mirai (JAMSTEC, Japan), and five other specimens were video recorded at depths between 210 and 340 m during three oceanographic expeditions …

Mondo: Integrating Disease Terminology Across Communities, Nicole A Vasilevsky, Sabrina Toro, Nicolas Matentzoglu, Joseph E Flack, Kathleen R Mullen, Harshad Hegde, Sarah Gehrke, Patricia L Whetzel, Yousif Shwetar, Nomi L Harris, Mee S Ngu, Gioconda L Alyea, Megan S Kane, Paola Roncaglia, Eric Sid, Courtney L Thaxton, Valerie Wood, Roshini S Abraham, Maria Isabel Achatz, Pamela Ajuyah, Joanna S Amberger, Lawrence Babb, Jasmine Baker, James P Balhoff, Jonathan S Berg, Amol Bhalla, Xavier Bofill-De Ros, Ian R Braun, Eleanor C Broeren, Blake K Byer, Alicia B Byrne, Tiffany J Callahan, Leigh C Carmody, Lauren E Chan, Amanda R Clause, Julie S Cohen, Marcello Deluca, Natalie T Deuitch, May Flowers, Jamie Fraser, Toyofumi Fujiwara, Vanessa Gitau, Jennifer L Goldstein, Dylan Gration, Tudor Groza, Benjamin M Gyori, William Hankey, Jason A Hilton, Daniel S Himmelstein, Stephanie S Hong, Charles T Hoyt, Robert Huether, Eric Hurwitz, Julius O B Jacobsen, Atsuo Kikuchi, Sebastian Köhler, Daniel R Korn, David Lagorce, Bryan J Laraway, Jane Y Li, Adriana J Malheiro, James Mclaughlin, Birgit H M Meldal, Shruthi Mohan, Sierra A T Moxon, Monica C Munoz-Torres, Tristan H Nelson, Frank W Nicholas, David Ochoa, Daniel Olson, Tudor I Oprea, Tomiko T Oskotsky, David Osumi-Sutherland, Kelley Paris, Helen E Parkinson, Zoë M Pendlington, Xiao P Peng, Amy Pizzino, Sharon E Plon, Bradford C Powell, Julie C Ratliff, Heidi L Rehm, Lyubov Remennik, Erin R Riggs, Sean Roberts, Peter N Robinson, Justyne E Ross, Kevin Schaper, Brian M Schilder, Johanna L Schmidt, Elliott W Sharp, Morgan N Similuk, Damian Smedley, Tam P Sneddon, Rachel Sparks, Ray Stefancsik, Gregory S Stupp, Shilpa Sundar, Terue Takatsuki, Imke Tammen, Kezang C Tshering, Deepak R Unni, Eloise Valasek, Adeline Vanderver, Alex H Wagner, Ryan F Webb, Danielle Welter, Doron Yaya-Stupp, Andreas Zankl, Xingmin Aaron Zhang, Julie A Mcmurry, Christopher G Chute, Ada Hamosh, Christopher J Mungall, Melissa A Haendel

Faculty, Staff and Students Publications

Precision medicine aims to enhance diagnosis, treatment, and prognosis by integrating multimodal data at the point of care. However, challenges arise due to the vast number of diseases, differing methods of classification, and conflicting terminological coding systems and practices used to represent molecular definitions of disease. This lack of interoperability artificially constrains the potential for diagnosis, clinical decision support, care outcome analysis, as well as data linkage across research domains to support the development or repurposing of therapeutics. There is a clear and pressing need for a unified system for managing disease entities⁠-including identifiers, synonyms, and definitions. To address these …

Field Notes, Sean T. Zadar, Dwight Chasar, Haans Petruschke, Bill Whan, Judy Semroc

Cleveland Bird Calendar

No abstract provided.

Field Notes, Ben Winger, Dwight Chasar, Ann Chasar, Dick Rickard, Bob Finkelstein

Cleveland Bird Calendar

No abstract provided.

Field Notes, Leo Deininger, Dick Rickard, Dwight Chasar

Cleveland Bird Calendar

No abstract provided.

Field Notes, Ed Pierce, Ben Winger, Scott Wright, Vernon Weingart

Cleveland Bird Calendar

No abstract provided.

Noteworthy Records, Larry Rosche

Cleveland Bird Calendar

No abstract provided.

Field Notes, John Pogacnik, Jean Hoffman, Dick Hoffman

Cleveland Bird Calendar

No abstract provided.

Field Notes, Robert Harlan, Rich Stallcup

Cleveland Bird Calendar

No abstract provided.

Field Notes, Larry Rosche, Ray Hannikman, Florian Graff, Andrew Fondrk

Cleveland Bird Calendar

No abstract provided.

Dna Barcoding Of Eight Freshwater Fish Species (Order Siluriformes) From The River Ravi, Pakistan, Hafiz Muhammad Ashraf, Hafiz Abdullah Shakir, Muhammad Irfan, Shaukat Ali, Chaman Ara, Noor Khan, Muhammad Khan, Abdul Qadir, Muhammad Zafar Saleem

Karbala International Journal of Modern Science

Pakistan's freshwater bodies host significant fish species, but molecular identification is still in its infancy, necessitating the use of morphological and molecular DNA barcoding techniques. The study confirmed the species of the order Siluriformes found in the River Ravi, Pakistan, using DNA extracted from muscle tissue, sequenced for the COI gene, and obtained accession and Barcode Index Numbers from GenBank and BOLD databases. In the BLAST search, identities ranged from 99.23–100% and 99.52–100% in the GenBank and BOLD databases, respectively. The study revealed that the Kimura 2-Parameter genetic distance increased from lower to higher taxonomic levels: within species (0.00%) < within genus (15.17%) < within family (19.77%). The study estimated average nucleotide differences (104.964) and nucleotide diversity (0.16099) but found Tajima's neutrality test to be statistically insignificant. The neighbor-joining tree displayed closely linked species under a node, whereas divergent species were grouped under distinct nodes. The COI gene-based DNA barcoding aids in Pakistan's fish resource inventory, monitoring, and management, providing valuable input for traditional methods.

Eco-Assisted Ultrasonic Synthesis, Characterization, And Electrical Conductivity Study Of Polyaniline/ Silica@Fe3o4 Q1 Nanocomposites, Ali Salim Shaway, Kholoud Dham Khamkheem, Jawad Kadhim Abaies, Athra G. Sager

Karbala International Journal of Modern Science

وفي هذه الدراسة الصوتية، أصبحت السيليكا المُنتجة بأكسيد الحديد (Fe₃O₄) ومركبات نانوية قائمة على البولي أنيلين مُطعّم بنسبة 5-15% من السيليكا المُعزز للحديد (Fe₃O₄). وأكملت نهائيا ماء أنيلين والمركبات العلمية المتنوعة الارتباط باستخدام تقنيات FT-IR وUV-Vis وXRD وSEM وTEM. وأحدثت نتائج XRD أن حجم جسيمات البولينج أنيلين الناي (PANI) يبلغ 55.5. مكثف هذا الحجم إلى 45.2 عند تطعيم بولي أنيلين بنسبة 15% وزناً من السيليكا المُغلفة بأكسيد الحديد (Fe₃O₄) مُحضّرة بطريقة جيدة بشكل جيد، مما يميل إلى التمدد بشكل ثابت في تشكيل المركب المتباين المنظم. ضاقت النطاق البصري من 3.2 إلى 2.5 إلكترون فولت مع زيادة نسبة المطعّم، مما يشير …

Ultrasound-Guided Percutaneous Sclerotherapy Of A Canine Hepatic Cyst Using Lower-Concentration Ethanol: A Case Report, Minyoung Kim, Dongyeong Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 10-year-old female Pomeranian was referred after a hepatic cyst was incidentally identified during a routine health check. Ultrasound-guided simple drainage was initially performed, and cytological examination of the aspirated fluid confirmed a simple cyst. However, the cyst re-expanded to its original size within 2 weeks. Therefore, ultrasound-guided percutaneous sclerotherapy was elected using lower-concentration ethanol (83%), a readily available medical disinfectant, rather than conventional high-concentration ethanol. Approximately 50% of the aspirated volume was replaced with 83% ethanol and retained for 20 min to achieve effective epithelial ablation. Post-procedural follow-up revealed a transient increase in cyst size and serum alanine aminotransferase …

Ultrasonography Accompanied By Genetic Testing In Feline Polycystic Kidney Disease, Thao Phuong Vu, Thong Quang Le, Ha Nguyen Nhat Tran, Khoa Hoang Dang Le, Anh Phu Nam Bui

The Thai Journal of Veterinary Medicine

Autosomal dominant polycystic kidney disease (ADPKD), caused by the PKD1 c.10063C>A mutation, is a prevalent inherited feline disorder, but its allele frequency in Vietnam remains unidentified. This study aimed to determine the carrier frequency of this variant in British Shorthair, Maine Coon, and Ragdoll cats in Ho Chi Minh City and to correlate genotype with ultrasonographic phenotype. Ninety-seven client-owned cats were genotyped for the pkd1 mutation using PCR-RFLP. A subset of 47 cats also underwent abdominal ultrasonography to detect renal cysts. Genotypic results were correlated with sonographic findings, and risk factors were analyzed using chi-square tests and odds ratios …

The Effects Of Sun Exposure On The Intensity And Distribution Of Salamander Biofluorescence, Julianne Chairez

Scholars Week

Salamanders have been used in a variety of different experiments to  determine the health of various ecosystems. Biofluorescence was recently studied in  amphibians in a study done in 2020. Not much is known about all its functions,  more studies are needed to fully understand how it works and how it can be affected  by environmental factors. Learning more about the functions of salamander  biofluorescence could lead to a greater understanding of how pollutants and human  impacts can affect salamanders and the health of their ecosystems. This project  aims to focus on tiger salamander biofluorescence and how its distribution and  intensity …

Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta

Michigan Tech Publications

Featured Application: This paper has important applications in environmental health risk assessment and urban soil remediation planning. By demonstrating how machine learning can predict lead bioaccessibility in lead paint-contaminated soil, the study provides a scalable, cost-effective alternative to laboratory-based extraction methods. Such models could support rapid screening of contaminated sites, helping prioritize high-risk areas for intervention and allocate remediation resources more efficiently. This model is expected to advance data-driven decision-making for managing lead-contaminated soils and protect vulnerable urban populations from exposure. Lead contamination in urban soils, primarily from deteriorating lead-based paint, poses a significant health risk in the United States. …

Entwurzelt, Melanie Fischer

Theses and Dissertations

Entwurzelt (Uprooted) is an installation that explores the emotional landscape of displacement-trauma, grief, and the search for belonging in the aftermath of war and unrest. The vessels in this installation evoke the presence of a forest--each one a symbolic tree, rooted in memory and shaped by personal and collective histories. Being torn from the familiar means leaving behind everything except memories and carrying a void that may never be fully filled. Yet, in unfamiliar places, fragments of comfort can be found--echoes of what once was. For me, the forest is more than a memory--it is a bridge between past and …

Characterization Of Srsf1’S Functions In Transcription And Alternative Splicing, Elena Bisotto

Electronic Theses and Dissertations 2020 - Present

Serine/Arginine splicing factor 1 (SRSF1) is an RNA-binding protein (RBP) that serves as a central regulator of RNA biogenesis. SRSF1 has been implicated in cell replication, motility, ageing, immune function, and other physiological processes, while its dysregulation is associated with multiple cancers and autoimmune diseases. In this study, we characterized the global impact and structural requirements of SRSF1-mediated gene regulation to elucidate its proto-oncogenic functions.

Utilizing a time-course RNA sequencing (RNA-seq) approach in HEK293 cells, we identified 28 primary transcriptional targets of SRSF1, 18 of which were consistently upregulated in the established cancer cell models PC-3 and MCF-7. These targets …

Quantitative Detection Of Chicken And Duck Derivatives In Pork Products Based On Digital Pcr Technique, Yang Xiaoli, Xin Le, Cui Ying, Li Hongduo, You Yaning

Food and Machinery

[Objective] To establish a polymerase chain reaction (PCR) quantitative detection method for chicken and duck adulteration in pork. [Methods] Primers and probes are designed based on single-copy genes specific to porcine, duck, and chicken. Then, a digital PCR quantitative detection method is established for derivatives in meat products, while verification is conducted on the detection limit, sensitivity, and specificity of the method. Additionally, a conversion coefficient K is introduced to convert copy number into the mass fraction of meat. Afterwards, the established method is applied to detect adulteration in 20 commercially available meat product samples. [Results] A digital PCR quantitative …

Comparison Of Amino Acids And Volatile Flavor Compounds In Various Parts Of Ternary Pig Meat, Li Rui, Wang Jingyu, Shi Xixiong, Zhang Aiwen, Yu Xuan, Xu Linna

Food and Machinery

[Objective] To scientifically evaluate the differences of amino acids and volatile flavor compounds in various parts of Ternary pig meat. [Methods] The composition of amino acids and volatile flavor compounds in front leg meat, hind leg meat, and longissimus dorsi muscle of the Ternary pig is compared and analyzed. [Results] The total amino acid content of fore limb meat, hind limb meat, and longissimus dorsi muscle is 16.13, 15.69, and 17.26 g/100 g, respectively. The essential amino acid content is 6.33, 6.12, and 6.71 g/100 g, respectively. The non-essential amino acid content is 9.79, 9.57, and 10.56 g/100 g, respectively. …

Opium Of The Masses: An Analysis Of Archeobotanical Research In The City Of Tábor, Czechia And How It Potentially Influenced Forms Of Radical Hussism, Sasha Gladding

Undergraduate University Honors Capstones

Opium of the Masses performs in depth analysis of the Hussite Wars–a time period lasting from 1419 to 1436, Jan Hus, Hussite factionalism, and archeobotany. This analysis proposes that there are numerous possible contributing factors to the development of the radical Hussite teachings and ways of life. The instability of the Catholic hierarchy and the dissenting teachings of Jan Hus also likely were contributors to the development of the unique sociopolitical and spiritual practices of the radical Hussites. It is also possible that the Hussite factions residing in the Czech (then Bohemian) town of Tábor utilized opium as an entheogen …

Head Shot, Joanmarie Ilaria Davoli

Mercer Law Review

The prohibition of cruel and unusual punishment in the Eighth Amendment of the U.S. Constitution requires that execution methods avoid “superadding pain.” The U.S. Supreme Court has held that the imposition of a death sentence should include no additional pain beyond that needed to kill. That means, for example, that while pain may be inherent in the method of killing, torture is prohibited. As concerns about the pain involved in lethal injections has increased, states have begun executions by shooting inmates in the heart and by suffocation through gas mask. These methods have been used despite evidence that they superadd …

Relational Histories: Exploring The Transmission Of Ceramic Technology In The Norton Sound Region Through Petrographic Analysis, Laurel Michelle Diciuccio

Dissertations and Theses

Ceramic technology in the Bering Strait region of the North American Arctic dates to approximately 2,500 BP and is broadly divided into two traditions: the Early Arctic (Norton, pre-1,500 BP) and the Late Arctic (Thule, post-1,500 BP). While Arctic ceramic studies have focused on raw material sourcing, vessel use, and cooking performance, this research investigates forming methods and ceramic fabrics to better understand their place in the technological behavioral chain. This approach fills a gap in the literature by centering on vessel construction and offers new insights from Norton Sound sites, including type sites Iyatayet and Nukleet.

Macroscopic and petrographic …