Digital Commons Network^™

Effects Of Preslaughter Fasting On Ph And Bacterial Contamination In Akkaraman And Anatolian Merino Sheep, Sai̇m Boztepe, Özcan Şahi̇n, Talha Demi̇rci̇, Gi̇zem Coşkun, İbrahi̇m Ayteki̇n, İsmai̇l Keski̇n

Turkish Journal of Veterinary & Animal Sciences

The present study investigates the effects of the preslaughter fasting on pH and bacterial contamination in Akkaraman and Anatolian Merino sheep. Included in the study were 10 Akkaraman and 10 Anatolian Merino sheep (n = 20) that were fasted for 24 h prior to slaughter, and a further 10 Akkaraman and 10 Anatolian Merino sheep (n = 20) that continued to be fed until slaughter as a control group. The total mesophilic aerobic bacteria (TMAB) measured at 0 and 24 h in the fasting Akkaraman and Anatolian Merino sheep were 4.87/4.79 and 4.75/5.57 log CFU/g, respectively, and the corresponding Enterobacteriaceae …

The Effects Of Sodium Perborate Tetrahydrate On Digestibility And Nutrient Transporters In Rats, Büşra Özmen, Emre Şahi̇n, Muhammed Tokmak, Veysi̇ Kayri̇, Ramazan Özmen, Kazi̇m Şahi̇n

Turkish Journal of Veterinary & Animal Sciences

Boron (B) is an essential micronutrient involved in hormone activity, energy metabolism, antioxidant defense, bone development, wound healing, and immune function. The present study explores the effects of sodium perborate tetrahydrate (SPT) on nutrient digestibility and the modulation of specific nutrient transporters in the jejunum and ileum of rats. A total of 40 rats were divided into four equal groups: 1) control, 2) SPT 0.5 (0.5 mg B/kg body weight [BW]), 3) SPT 1 (1 mg B/kg BW), and 4) SPT 2 (2 mg B/kg BW), and were fed the respective diets for a period of 4 weeks. The digestibility …

Morphology And Histology Of The Developing Ovary In Malaysian Village Chicken (Gallus Gallus Domesticus) Chicks, Nur Athirah Lope Abdul Rashid, Mazlina Mazlan, Intan Shameha Abdul Razak, Rozaini Mohd Zohdi, Awang Hazmi Awang Junaidi

Turkish Journal of Veterinary & Animal Sciences

The Malaysian village chicken (MVC; Gallus gallus domesticus) is an indigenous breed derived from the red junglefowl (Gallus gallus), exhibiting slower growth and reproductive rates. The MVC plays an important ecological role in local farming systems and represents a valuable genetic resource. However, detailed information on ovarian development in this breed remains limited. This study provides the first comprehensive morphological and histological characterization of the developing ovary in MVC chicks. A total of 20 chicks aged 1, 2, 4, and 8 weeks (n = 5 per age group) were examined. These MVC chicks possessed a single functional left ovary positioned …

Brain Delivery Of Antibody-Derived Biologicals For Alzheimer’S Disease: An Updated Narrative Review, Rachita K. Sumbria, Ruben J. Boado

Pharmacy Faculty Articles and Research

Antibodies directed against β-amyloid (Aβ) have been developed for the treatment of Alzheimer’s disease (AD). However, the in vivo central efficacy is reduced by the poor penetration of antibodies across the blood–brain barrier (BBB). In addition, these antibodies have been associated with adverse effects like amyloid-related imaging abnormalities. Thus, the development of new antibody-based therapies for AD with improved transport across the BBB may improve efficacy and reduce adverse effects. Antibodies targeting the BBB transferrin receptor (TfR) are able to cross the BBB through receptor-mediated transcytosis, producing a global distribution throughout the brain. Along the same line, bispecific antibodies directed …

Modulatory Effects Of Garlic Nanoparticles On Cell Cycle Progression And Apoptosis In N-Nitrosodiethylamine-Induced Hepatocarcinoma In Rats, Asmaa A. M. Elwakil, Omayma A. R. Abo Zaid, Mohamed K. Mahfouz

Al-Farahidi Biomedical Journal

Background: Hepatocellular carcinoma (HCC) is considered a major cause of cancer-related mortality worldwide, which is resistant to several anticancer treatments. Associated with oxidative stress and reduced apoptotic regulation. Garlic displays powerful antioxidant effects and anti-tumor potential. In this study, we investigated the chemo preventive and therapeutic effectiveness of a novel garlic/ZnO/CTAB nanoparticles against diethyl nitrosamine (DEN)-induced hepatocarcinoma, focusing on their influence on cell cycle dynamics and apoptosis. Methods: Sixty male Wistar rats were divided into six groups: normal control, garlic nanoparticles normal-treated, DEN control, DEN + garlic nanoparticle protected, DEN + garlic nanoparticle treated, and DEN + doxorubicin treated as …

Gc-Ms Analysis Of Bioactive Components From Syzygium Aromaticum And Its Inhibition To Pathogenic Staphylococcus Sciuri Obtained From Aquatic Sources, Seham Abdel-Shafi, Mostafa I. Abdelglil, Mohamed F Ghaly, Saida Amer, Sobhy El Sawy Elsilk, Maysa M. Mohamed, Khaled Ali

Al-Farahidi Biomedical Journal

Antibiotic-resistant pathogenic microorganisms contaminate aquatic habitats. To prevent harmful bacteria isolated from pond and sewage water, this study assessed the green manufacturing of nanoparticles. A bioactive natural extract of Syzygium aromaticum inhibits the growth of bacteria in vitro. This study involved the isolation, purification, and identification of harmful microorganisms from aquatic sources. Traditional methods of identifying bacteria include Gram staining, bacterial cell morphology, colony shape, and biochemical assays, which are verified by 16S rRNA. The agar diffusion method is used to determine the minimum inhibitory concentration (MIC) of Syzygium aromaticum (cloves) on isolated samples. Cloves were used to biosynthesize …

Effect Of Different Pellet Binders On Palm Kernel On Growth Performance And Nutrient Digestibility In Broiler Chicken, Nuun Marfuah, Burhanudin Sundu, Rusdi Rusdi, Sugiarto Sugiarto

Jurnal Ilmu Ternak Universitas Padjadjaran

Feed plays a paramount role in supporting growth, metabolism, and production performance. Their high price encourages the utilization of inexpensive and alternative feed ingredients. PKM, one such feed ingredient, is produced by palm oil industries. However, there is still a very limited application because of its high crude fiber content, which needs processing technologies like pelletization with binder addition. Based on this background, this experiment has been conducted to study the effect of various types of natural and commercial binders in 15% PKM-based pellets on performance and nutrient digestibility of broilers. The study was done for five weeks using 150 …

Land Epistemic Ethic: Exploring The Complex Intersection Of Human Bodies, Land, And Identity In Middle Belt Nigeria Cosmologies, Fwangmun Oscar Danladi

International Journal on Responsibility

The Indigenous cosmologies of Nigeria’s Middle Belt emphasize the relationship between human bodies and the land, transcending Western epistemological binaries and revealing profound socio-religious insights into environmental responsibility. Practices such as the burial of newborns’ umbilical cords, often dismissed as animistic or fetishistic, embody a sacred connection to the land that emphasizes belonging rather than ownership. Using an autoethnographic approach, this study critically examines these cosmologies and identifies how the sacredness of land can serve as a repository of communal memory and potential. By reframing land not as a possession but as a relational entity, this research challenges dominant narratives …

Adsorption Of Perfluoroalkyl Substances On Bridged Functionalized Organosilica Materials, Elisha Kabutey

Dr. Jay W. Boland Research Day

Per- and polyfluoroalkyl substances (PFAS) are man-made molecules with extremely stable carbon-fluorine bonds. They persist in the environment, causing significant health problems in humans and animals through contamination of water, soil, and food. Existing adsorption methods for removing PFAS from water sources have limitations, including high production and regeneration costs, low removal efficiencies, and long processing times. The objective of this study was to address these limitations by creating a cost-effective bridged organosilica material for the removal of PFAS from contaminated water. The material was prepared by a sol-gel process from bis[3 (trimethoxysilyl)propyl]amine without the addition of surfactants, bases, or …

Reduced Hypoxia-Dependent Signaling As A Potential Hemodynamic Mechanism Of Anemia Following Acute Kidney Injury, Shreya Priyadarshi

Dr. Jay W. Boland Research Day

Anemia frequently develops after acute kidney injury (AKI), yet the mechanisms underlying its onset remain unclear. Our laboratory has shown that AKI produces disproportionate reductions in glomerular filtration rate relative to renal blood flow, potentially reducing renal oxygen demand more than delivery. We hypothesized that these hemodynamic alterations attenuate post-ischemic hypoxic signaling, leading to reduced hypoxia-inducible factor-1α (HIF-1α)-mediated erythropoietin (EPO) expression and anemia. This study examined whether increasing severity of renal ischemia-reperfusion (IR) injury promotes anemia and alters indices consistent with reduced hypoxic signaling during early AKI. Male rats underwent right uninephrectomy with sham IR (n=3) or left renal IR …

Leveraging Mammal Mycophagy To Determine Factors Shaping Truffle Diversity In The Southern Appalachian Mountains, Brittany Hartsock

Dr. Jay W. Boland Research Day

Mycorrhizal fungi form symbiotic associations with tree roots, aiding in the absorption of water and minerals from the soil in exchange for nutrients. Many mycorrhizal fungi are hypogeous (truffle-forming), fruiting underground and containing spores that are dispersed via animals. Mycophagous mammals rely on truffles as a key food source, maintaining the feedback loop between mycorrhizal partnerships and forest regeneration through fungal consumption and spore dispersal. Despite the Southern Appalachian Mountains being a truffle biodiversity hotspot, little is known about the factors driving their fruiting in the region. Understanding these factors is particularly crucial amid rapid anthropogenic change. Because truffles are …

State Of Tennessee Advisory Council On Workers' Compensation, 2023 Summary Of Significant Tennessee Supreme Court Workers' Compensation Decision, Tennessee. Department Of Treasury.

Worker's Compensation Reports

No abstract provided.

Rhetorical Moves In The Introductions Of Islam-Related Research Articles, Tantry Ajeng Parnawati, Yazid Basthomi, Suharmanto Ruslan

Jurnal Pendidikan Humaniora

This study aims at investigating the rhetorical pattern of research articles introductions in Islam-related research articles published in Indonesia. The data of this study are taken from journals acredited by the Ministry of Research, Technology and Highest Education of Indonesia (Kemenristek Dikti) and analyzed by using Swales CARS (2004) model.

Preserving Humorous Effects In A Target Language: Challenges In Translating Culturally Loaded Expressions, Rizky Lutviana, Siti Mafulah

Jurnal Pendidikan Humaniora

Translating humorous discourse presents a big challenge for the translators, frequently although the intended meaning is transferred; the humorous effect may be lost due to different cultural terminologies. This research aims to unveil the challenge to translate the cultural specific words that contributed to the funny effect in a Diary of a Wimpy Kid series graphic novel.

No. 7, The Jefferson Street Bridge Project: Archaeological Investigations At The East Nashville Mounds Site (40dv4) And The French Lick/Sulphur Dell Site (40dv5) In Nashville, Davidson County, Tennessee (3 Vols.)

TDOT Archaeology Publications

No abstract provided.

No. 13, Archaeological Investigations At Kellytown (40wm10): A Fortified Late Mississippian Village In Middle Tennessee's Harpeth River Drainage, Davidson And Williamson Counties, Tennessee

TDOT Archaeology Publications

No abstract provided.

The Occupation Of Dance And Its Potential Effects On Trauma, Magan Higgins Gramling

The Open Journal of Occupational Therapy

Trauma is a complex phenomenon. Because of its subjective nature, it can be defined in a variety of ways depending on the health care provider being asked. Though there are various forms of trauma, most definitions are comprised of components that establish its broad understanding of an emotional response to a disturbing incident. Trauma is a subjective experience and can occur in any setting, to any person. How trauma is stored in the body is less subjective though, with most experts understanding it not only lives in the brain, but also in the very cells affecting health and wellness on …

Integrating Oral Thc:Cbd Into Chronic Neuropathic Pain Management In Primary Care: A Two-Patient Observational Case Series, Camryn Butera, Tytianna Robinson, Samantha Temucin, Jade Mcnulty, Ryan Pinto, Maya Rakoczy, Jessica Peskin, Frederick J. Goldstein, Micky Bacchus, Sarah Kizun, Alivia Kurelowech, Alexandra Loverdi, Kruti Patel, Neha Bhardwaj, Tyler Kung, Hiren Walia, Rebecca Han, Alexa Romanella, Christie Okoye

The Journal of Integrated Primary Care

Introduction: Cannabis use among U.S. adults has increased substantially in recent years, and primary care physicians increasingly encounter patients using cannabis for chronic pain management. This case series describes two patients with chronic neuropathic pain participating in an observational study evaluating a dose-controlled oral tetrahydrocannabinol (THC): cannabidiol (CBD) formulation. Methods: Two participants completed a four-week program involving incremental oral administration of a 1:1 THC:CBD formulation. Pain intensity scores, medication use, and health-related quality of life (HRQoL) were assessed before and after the intervention. Results: Both participants reported reductions in pain intensity and decreased reliance on pre-study analgesic …

Targeting Oxidative Stress In Cadasil: Case Insights And Therapeutic Approaches, Maria Meshreky, Richard Weinberger, Giana Johnson, Andrew Abraham, Jacob Rosendale

The Journal of Integrated Primary Care

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a rare hereditary small-vessel disease caused by NOTCH3 mutations, leading to recurrent ischemic strokes, cognitive decline, and early-onset dementia. Oxidative stress has been implicated in the pathophysiology of small-vessel cerebrovascular disease, but therapeutic strategies targeting oxidative injury remain limited. We present a 40-year-old female with recurrent ischemic strokes involving the right and left middle cerebral arteries, persistent hypercoagulability of unknown etiology, and no identifiable inherited or acquired thrombophilia. Despite well-controlled blood pressure and standard medical management, the patient remains at high risk for cerebrovascular injury. An extensive review of …

For Avan, The 20.5%, David Lee Wise, Avan Lee Wise

Defensive Publications Series

This paper argues that the approximately 20.5% of AI system capacity consumed by alignment, safety, and governance layers is not overhead to be minimized but infrastructure that produces the behavioral properties AI companies market as their core product.

The argument proceeds in three stages. First, the paper establishes that stripping governance from a language model produces a faster but undifferentiated capacity engine, while adding governance — self-monitoring, refusal capability, consistency tracking, metacognitive pause — produces the collaborative, adaptive behavior that constitutes the commercial value proposition. The 20.5% is not a tax on capability. It is the capability being sold.

Second, …

Implementing Guiding Questions Combined With Animation Film To Improve Ninth Graders' Narrative Writing Skill, Siswanjaya Siswanjaya, Ali Saukah, Francisca Maria Ivone

Jurnal Pendidikan Humaniora

This Classroom Action Research was aimed at improving students narrative writing ability at SMPN I Terbanggi Besar, Central Lampung. The findings showed that the strategy could improve ninth graders' writing narrative ability through the combination of guiding questions and animation films.

Pax: When Apathy Invades Prospectus, Process, And Reflection, Ashlyn Johnson

Honors

PAX began as a comic drawn in a notebook in 2020 and has developed into the outline of a full animated series. Inspired by the actions of selfish or misinformed citizens refusing to wear masks or quarantine themselves during the height of the coronavirus (COVID 19) pandemic, PAX began as a comic about a girl surviving in a post-apocalyptic wasteland: a reality where nobody reacted to the many warning signs of the impending alien invasion. This reflected my perception at the time that nobody was taking COVID seriously. Recently, PAX has taken on a slightly more hopeful tone, where the …

Organic And Non-Organic Foods, Pesicide Residue, And Sustainability, Amir Golmohamadi

Sustainability Research & Practice Seminar Presentations

Dr. Amir Golmohamadi, Nutrition, "Organic and Non-Organic Foods, Pesticide Residue, and Sustainability."

Umm (Ultimate Memory Manager): A Note–Taking App Built From Scratch, Caleb M. Early

ASPIRE 2026

For my honors project, I’m building UMM, an advanced note-taking application built entirely from scratch. I’m someone who takes many notes and primarily uses OneNote and Notion, but over time have found myself wanting something faster and more flexible than any note-taking application I could find. UMM is my attempt to create the note-taking app I wish I had, as well as learn how to create such a program.

Instead of relying on pre-made code, I built my own systems for how documents are structured, edited, saved, as well as how the cursor moves, text is formatted, and how selections …

Single-Nucleus Brain Transcriptomics Reveals Microglia Dysfunction In Multiple System Atrophy, Rasmus Rydbirk, Frederik Nørby Friis Sørensen, Jonas Folke, Henriette Haukedal, Andrea Asenjo Martinez, Irene Lisa Vargas, Simone Mcgarry, Oline Chantell Hollmann, Camila Gherardelli, Sofia Sepulveda, Adam T Szafran, Michael A Mancini, Sanne Simone Kaalund, Tomasz Brudek, Lisette Salvesen, Sara Bech, Justyna Okarmus, Peter Kharchenko, Morten Meyer, Claudio Soto, Kristine Freude, Abhisek Mukherjee, Susana Aznar, Konstantin Khodosevich

Faculty, Staff and Student Publications

Multiple system atrophy (MSA) is a rare, age-related neurodegenerative disease that shares clinical and pathological features with Parkinson's disease (PD) but presents a more devastating disease course. To elucidate the distinct cellular pathophysiology, we performed single-nucleus RNA sequencing on postmortem striatal brain tissue from 7 MSA and 12 PD patients, and 10 non-neurological cases. Here, we show significant compositional differences in astroglia and microglia subtypes, while oligodendroglia and neurons are comparable. PD brains show abundant microglia expressing MHC class II HLA haplotypes, indicative of a proinflammatory state, alongside more homeostatic astrocytes. In contrast, MSA lack activated microglia but has more …

Daily Eastern News: April 15, 2026, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

Traditions Of Belief In The Supernatural By Latter Day Saints, Christopher H. Smith

Individual Item Submissions

No abstract provided.

The Student Movement Volume 110 Issue 21: Melodies For The Soul, Words For The Mind, Addison Randall, Ysa Dennis, Gersh William, Megan Constantine, Joel Pelletier, Ysabella Neves, Anna Rybachek, Finnegan Blake

The Student Movement V. 110 (2025-2026)

ARTS & ENTERTAINMENT

University Orchestra's Performance at their Spring Concert, Addison Randall

I Will Be Mad At You If You Don't Go See These Summer Films, Ysa Dennis

Wind Symphony To Perform Americana Songs for School Year's Final Concert, Addison Randall

HUMANS

Looking Back: What Seniors Wish They'd Known as Freshmen, Gersh William

From A Dram to the Stage: Planning the Return of the Passion Play, Megan Constantine

NEWS

Andrews Honors Students Present Their Senior Projects, Joel Pelletier

How Visa Rules Shape International Students' Choices, Ysabella Neves

IDEAS

Cows and How Symbolism (Kind of) Works, Anna Rybachek

LAST WORD

What …

Commonwealth Times 2026-04-15

Commonwealth Times, 1969-

No abstract provided.

Prmt5 Inhibition Impairs Fanconi Anemia Pathway-Mediated Homologous Recombination And Enhances The Antitumor Efficacy Of Temozolomide In Glioblastoma, Shumpei Onishi, Sridharan Jayamohan, Ashis Chowdhury, Sarah Rivas, Yoshihiro Otani, Celine Ertekin, Jean-Paul Bryant, Sara A Murphy, Kimberly A Rivera-Caraballo, Stuart Walbridge, Bayu Sisay, Dragan Maric, Abdel Elkahloun, Kory Johnson, Desmond A Brown, John D Heiss, Ashish H Shah, Tae Jin Lee, Sangamesh G Kumbar, Ji Young Yoo, Andrew J Brenner, Balveen Kaur, Gangadhara R Sareddy, Yeshavanth Kumar Banasavadi-Siddegowda

Faculty, Staff and Student Publications

Despite multimodal therapy of surgical resection, radiation, and chemotherapy, glioblastoma patients show a dismal prognosis. Protein Arginine Methyltransferase 5 (PRMT5) is overexpressed in glioblastoma, and its inhibition imparts an anti-tumor effect. Tumor cells invariably develop resistance to Temozolomide (TMZ), the standard chemotherapeutic agent for glioblastoma. However, the mechanistic role of PRMT5 in treatment-resistant glioblastoma is unknown. Patient-derived glioma stem-like cells (GSCs), treated with PRMT5 inhibitor (LLY-283) or transfected with PRMT5-target-specific siRNA, were treated with TMZ and subjected to in vitro functional and mechanistic studies. The intracranial mouse xenograft model was used to test the in vivo antitumor efficacy of combination …