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Articles 3061 - 3090 of 14349
Full-Text Articles in Entire DC Network
The Effect Of Aquatic Pollution On (Green) Microbial Communities In The Greater Rochester Area, Francesca Molee
The Effect Of Aquatic Pollution On (Green) Microbial Communities In The Greater Rochester Area, Francesca Molee
Theses
Retention ponds are built in urban and suburban areas to catch the polluted runoff that would otherwise go into highly-valued freshwater ecosystems like the Great Lakes. They therefore make ideal model ecosystems to consider the effect of chemical, common pollution on aquatic communities. To understand the impact this aquatic pollution on both microbial community composition alongside green microbial physiological stress response, water column and sediment microbial communities were sampled from three retention ponds, and three non-retention, created ponds. The first part of this study focused on the microbial community composition. Using 16s amplicon sequencing on and subsequent analysis using Qiime2, …
Colostrum Management For Dairy Calves: Key Practices For Calf Health And Performance, Drew Swartz, Jacob Hadfield, Kalen Taylor, Maggi Mathews
Colostrum Management For Dairy Calves: Key Practices For Calf Health And Performance, Drew Swartz, Jacob Hadfield, Kalen Taylor, Maggi Mathews
All Current Publications
This fact sheet provides practical recommendations for dairy producers to improve colostrum management and support calf health and performance.
Program (Pdf), Department Of Orthopaedics
Program (Pdf), Department Of Orthopaedics
Dept. of Orthopaedics: Robert D. D’Ambrosia Lectureship & Research Day
Program with abstracts for the 22nd Annual Dept of Orthopaedics Annual Robert D. D’Ambrosia Lectureship & Research Day held June 20, 2026.
Vector-Borne Viral Diseases In Horses, Sunutcha Suntrarachun
Vector-Borne Viral Diseases In Horses, Sunutcha Suntrarachun
The Thai Journal of Veterinary Medicine
Vector-borne viral diseases are major threats to equine health worldwide. These infections are transmitted by arthropod vectors such as mosquitoes, biting midges, and horseflies, resulting in clinical manifestations ranging from mild febrile illness to severe neurological, respiratory, circulatory, or hematologic disorders with high mortality rates. Major equine vector-borne viral diseases include African horse sickness (AHS), equine infectious anemia (EIA), equine encephalomyelitis (Eastern: EEE, Western: WEE, and Venezuelan: VEE), West Nile virus (WNV), and Japanese encephalitis (JE). Each disease is caused by a distinct viral pathogen and transmitted by specific vectors that influence their epidemiology and geographic distribution. Transmission occurs through …
Reference Values For Intraocular Pressure In Collared Scops Owls (Otus Lettia) Measured Using Rebound Tonometry, Yun-Shan Chiu, Chau-Hwa Chie, Pin-Huan Yu, Chung-Tien Lin
Reference Values For Intraocular Pressure In Collared Scops Owls (Otus Lettia) Measured Using Rebound Tonometry, Yun-Shan Chiu, Chau-Hwa Chie, Pin-Huan Yu, Chung-Tien Lin
The Thai Journal of Veterinary Medicine
In this study, we aimed to establish species-specific reference values for intraocular pressure (IOP) in clinically healthy collared scops owls (Otus lettia) using rebound tonometry. Twelve free-living owls were included, and twentyfour eyes were examined. All owls were physically restrained in an upright position without sedation. Intraocular pressure was measured in both eyes using rebound tonometry (TONOVET; iCare Finland Oy, Vantaa, Finland) in d mode. No significant difference in IOP was observed between the right and left eyes. The mean IOP values were 10.42 ± 1.24 mmHg (median, 11 mmHg; range, 8–12 mmHg) in the right eye and 10.75 ± …
Calibration And Validation Of An Ogden Material Model For Thermoplastic Polyurethane In 3d-Printed Tensegrity Structures, Caleb C. Swain
Calibration And Validation Of An Ogden Material Model For Thermoplastic Polyurethane In 3d-Printed Tensegrity Structures, Caleb C. Swain
Theses and Dissertations
This work is motivated by ongoing efforts within the Smart Materials, Adaptronics, and Shock Laboratory (SMASH Lab) at Brigham Young University (BYU) to develop variable-stiffness, external fixators using 3D-printed tensegrity structures. In the process of designing and evaluating these systems, the need arose to accurately model the nonlinear mechanical behavior of thermoplastic polyurethane (TPU), the primary material used in prototype fabrication. This thesis investigates how accurately a calibrated Ogden material model can predict the nonlinear mechanical response of TPU in 3D-printed tensegrity structures. Experimental data were used to calibrate the parameters of the hyperelastic constitutive model through nonlinear optimization. An …
From The Edge To The Grounds Of “Sentientism”, David Degrazia
From The Edge To The Grounds Of “Sentientism”, David Degrazia
Animal Sentience
Birch’s book is a remarkable exploration of the nature of sentience, its moral salience, evidence for its presence, and how to arrive at humane policies regarding our treatment of human beings, animals, brain organoids, and AI systems of uncertain sentience. Although Birch endorses the view that sentience is of fundamental moral importance, he endeavors to remain neutral among reasonable moral views and work out how to navigate through uncertainty—both ethical and epistemological—to arrive at defensible policies. While making common cause with Birch’s project, my own recent book advances a developed case in favor of the “sentientism” Birch endorses.
Prmt5 As A Key Driver Of Stemness And Metastatic Potential In Triple-Negative Breast Cancer, Jae Jin Jeong, Mauli Maniar, Shahrzad Ghane, Sakshi Deshpande, Claire Ellis, Ashakumary Lakshmikuttyamma
Prmt5 As A Key Driver Of Stemness And Metastatic Potential In Triple-Negative Breast Cancer, Jae Jin Jeong, Mauli Maniar, Shahrzad Ghane, Sakshi Deshpande, Claire Ellis, Ashakumary Lakshmikuttyamma
College of Pharmacy Faculty Papers
Protein arginine methyltransferase 5 (PRMT5) mediates arginine methylation of a wide range of proteins and plays context-dependent oncogenic or tumor-suppressive roles. In cancer, PRMT5 represses several tumor suppressor genes, including E-cadherin, TP53BP1, ST7, PTEN, and RB (retinoblastoma). Elevated PRMT5 expression has been reported across multiple cancer types, notably triple-negative breast cancer (TNBC). In TNBC, high PRMT5 levels are associated with enhanced cancer stem cell self-renewal, increased tumor growth and metastasis, and reduced patient survival. Mechanistically, PRMT5 promotes breast cancer stem cell maintenance and proliferation through stabilization of the transcription factors KLF4 and KLF5. Disruption of the PRMT5-KLF4 axis results in …
The Effect Of Flaxseed Oil On Fertility, Mohammad F. Albadran, Ahmed B. Abdulwahid, Assad H. Eissa, Nehaya M. Al-Aubody, Shaymaa F. Abbas, Zainab M. Mohammed
The Effect Of Flaxseed Oil On Fertility, Mohammad F. Albadran, Ahmed B. Abdulwahid, Assad H. Eissa, Nehaya M. Al-Aubody, Shaymaa F. Abbas, Zainab M. Mohammed
Hilla University College Journal For Medical Science
Background: Infertility can be defined as the inability to conceive pregnancy when sexually active and not having used any contraception in 12 months. Flaxseed oil has wide-spectrum applications in health. It has been receiving special interest in infertility treatment.
Objectives: This research aimed to determine the impact of flaxseed oil on the fertility of mice.
Methods: It involved seventy-five mice. These mice were sex-separated and randomly classified into three groups; one group served as a control group, and the other two groups were exposed to flaxseed oil extract at a dose of 60 mg/Kg body weight/day or 120 mg/Kg body …
Factors Associated With Discharge Against Medical Advice Among Patients Attending The Emergency Departments In Babylon Governorate, Hasan Alwan Baiee, Ali Mohsen Al-Jobury, Ola Mosheb
Factors Associated With Discharge Against Medical Advice Among Patients Attending The Emergency Departments In Babylon Governorate, Hasan Alwan Baiee, Ali Mohsen Al-Jobury, Ola Mosheb
Hilla University College Journal For Medical Science
Background: With the increasing number of patients leaving the emergency department against medical advice, morbidity, mortality, and readmission rates have risen, placing a strain on the healthcare system.
Objectives: This study aimed to identify the demographic characteristics and the reasons why patients left against medical advice among those attending the emergency departments of teaching hospitals in Babylon Governorate.
Materials and Methods: A descriptive cross-sectional study was conducted in Babylon Governorate, encompassing three hospitals. using a convenience sample of patients who left the hospital against their physician's advice. Data were collected between August 2024 and February 2025 using a semi-structured questionnaire …
Infection By Entamoeba Histolytica Among Children Attending Maysan Pediatric And Maternity Hospital In Amarah City, Ali Idan Al-Musaedi, Ahmed Hussain Rahim
Infection By Entamoeba Histolytica Among Children Attending Maysan Pediatric And Maternity Hospital In Amarah City, Ali Idan Al-Musaedi, Ahmed Hussain Rahim
Hilla University College Journal For Medical Science
Background: Most parasites impose some level of damage to their hosts. Factors such as the number of parasites, the site of infection, the size and mobility of the parasite, along with the host's physiological condition and whether it serves as an intermediate or final host, affect the severity of infections in both humans and animals.
Objectives: To determine the prevalence of Entamoeba histolytica infection in children under the influence of some risk factors.
Materials and Methods: A total of 1213 stool samples were collected from children attending Maysan Pediatric and Maternity Hospital in Amarah City, Maysan Governorate, southern Iraq. Microscopy …
Fragile Hope And The Cultural Life Of Law, Shefali Jain
Fragile Hope And The Cultural Life Of Law, Shefali Jain
Socio-Legal Review
This review of Sandhya Fuchs’ Fragile Hope: Seeking Justice for Hate Crimes in India (Stanford University Press 2024) highlights that the book makes a genuinely original ethnographic and conceptual contribution to caste studies and hate crime scholarship. At the same time, the essay argues that there are three limitations to its framework that require greater engagement: the book’s failure to engage with the legal consciousness tradition in socio-legal scholarship, an underdeveloped account of “legal meliorism,” and an unresolved tension between the book’s stated commitment to victim-centred analysis and its ethnographic evidence that frequently discusses movement-level aspirations.
Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori
Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori
Al-Bahir
Globally, the issue of air pollution keep being one of most serious challenges that affecting environment and human health, coming from emissions of industries, transport, agriculture and also from the fuel people use in homes, in addition to natural events that make the situation worse. This review try to bring together the available evidences about the sources, types, and the health impacts of the main air pollutants, including the gaseous ones like SO₂, O₃, NO₂, and CO, and the particulate matter (PM₁₀, PM₂.₅). Exposure for short or long time to these pollutants is linked with many harmful outcomes, such as …
Investigations On The Effect Of Nano Titanium Oxide On The Properties Of Nickel Alloy Using Powder Metallurgy Technique, Sawsan F. Ahmed, Muaamar A .Kamil
Investigations On The Effect Of Nano Titanium Oxide On The Properties Of Nickel Alloy Using Powder Metallurgy Technique, Sawsan F. Ahmed, Muaamar A .Kamil
Al-Bahir
Powder metallurgy method was used to prepare nickel-based samples enriched with nano-chromium at a fixed ratio of 5 %wt. Different percentages of nano-titanium oxide were added at (0, 5, 10, 15, 20) %wt. . A 10 mm diameter die was used and the pressing process was carried out with a hydraulic press in one direction at a pressure of 10 tons. The resulting alloys were sintered at 1000°C for two hours. Several tests were performed, including X-ray diffraction of the primary and post-mixed powders, which showed that the nickel was in the FCC (Cubic) system and completely pure, the nano-chromium …
From Athens To Jerusalem: Platonism, Richard Owen, And The Road Not Taken In Biology, Michael A. Flannery
From Athens To Jerusalem: Platonism, Richard Owen, And The Road Not Taken In Biology, Michael A. Flannery
Libraries Professional Work
Tertullian provocatively asked (circa 200 AD), “What indeed has Athens to do with Jerusalem? What concord is there between the Academy and the Church?” The relationship between formal philosophy and religion has been a contentious battleground ever since. It has historically come into sharpest focus in biology generally, and evolutionary theory specifically. Charles Darwin clearly won the day in the short-term. His evolutionary functionalism looked like an inglorious abandonment of time-honored metaphysical realism for positivist empirical reductionism with a concomitant horizontalization of perspective that has secularized and flattened the intellectual landscape. But more recently the rise of evo-devo (evolutionary developmental …
Exploring Teachers' Perceptions Of The Influence Of Social Emotional Competencies On Virtual Students' Academic Success, Melanie Cheyanne Spence
Exploring Teachers' Perceptions Of The Influence Of Social Emotional Competencies On Virtual Students' Academic Success, Melanie Cheyanne Spence
Student Theses and Dissertations
The problem addressed in this study is that the effects of Social Emotional Learning (SEL) competencies on academic achievement for virtual learners in a Grades 5-8 classroom are not well known. The purpose of this qualitative narrative study was to explore teachers’ perceptions of how the practice of SEL competencies by students influence their academic success in a virtual Grades 5-8 classroom. This qualitative narrative inquiry was based around Social Emotional Learning (SEL), a conceptual framework identified by CASEL as including five competencies: self-awareness, self-management, social awareness, relationship skills, and responsible decision-making. The target audience was educational stakeholders who are …
Assessing The Effectiveness Of Wetland Reserve Easements As Habitat For Birds In The Mississippi Alluvial Valley Of Eastern Arkansas, Colin K. Dobson
Assessing The Effectiveness Of Wetland Reserve Easements As Habitat For Birds In The Mississippi Alluvial Valley Of Eastern Arkansas, Colin K. Dobson
Student Theses and Dissertations
Globally, wetland habitats suffered major declines during the 20th century. In the 1990s, the United States government created the Wetland Reserve Program (later consolidated into the Agricultural Conservation Easement Program), to combat the loss of wetlands. Despite success in attracting landowners, minimal monitoring of properties enrolled into the program (easements) has occurred. In this study, we monitored avian communities at easements, compared avian diversity at easements to agriculture and bottomland forests, and quantified microhabitat, site-specific, and surrounding landscape features at easements. We also studied the demographic rates of an indicator species of bottomland forests, the Prothonotary Warbler (Protonotaria citrea) at …
"Using A Sledgehammer To Crack A Nut" A Proposal To Re-Frame The Media Industry's Perspective On Generative Ai, Reace Barnett
"Using A Sledgehammer To Crack A Nut" A Proposal To Re-Frame The Media Industry's Perspective On Generative Ai, Reace Barnett
Student Theses and Dissertations
Generative Artificial Intelligence (GenAI) continues to be a divisive topic in the media industry and there are concerns about technical challenges that may affect GenAI’s trustworthiness and reliability. As such, fears of degraded public trust in media products and services have arisen, and while we have a tendency to trust machines, it is clear that public attitudes toward automated decision-making are contentious. Previous research on machine cues found that they are associated with increased perceived objectivity and willingness to disclose information. Conversational GenAI may reduce political polarization, yet many people remain worried about risks such as bias, hallucinations, improper attribution, …
Natural Behavior Vs. Subjective Experience In Fish Welfare Assessments, Ronald G. Oldfield
Natural Behavior Vs. Subjective Experience In Fish Welfare Assessments, Ronald G. Oldfield
Animal Sentience
Several commentaries on the Oldfield & Bonano (2024) target article proposed that natural behavior should play a larger role in assessing the welfare of fishes in zoos and aquariums. However, the natural-behavior concept of animal welfare has been widely criticized because natural behaviors do not necessarily improve welfare, and unnatural behaviors do not necessarily reduce it. I review the three major concepts of animal welfare — physical health, natural behavior, and affect/feelings — and argue that behavior patterns, whether natural or otherwise, should be evaluated according to their effects on health and subjective experience. Using the affect/feelings concept and the …
Assessing Rural Homelessness: A Mixed-Methods Case Study, Matthew J. Lyons
Assessing Rural Homelessness: A Mixed-Methods Case Study, Matthew J. Lyons
Faculty Articles
Rural homelessness represents a significant public health and human rights challenge, but research on homelessness in the United States has predominantly focused on urban settings. This case study describes a mixed-methods assessment of the prevalence, causes, and consequences of homelessness in a rural county. Through both surveys and interviews with stakeholders from multiple sectors (including both service providers and those experiencing homelessness), we built a rich picture of the scale and experiential dimensions of homelessness within the county. Here, we present our research methods, the main findings of each primary data collection arm, and the actionable conclusions drawn from the …
The Ecotoxicological Implications Of Switching From Fluorescent To Light Emitting Diode Lighting For Zooplankton Culturing And Whole Effluent Toxicity Testing, Orithea Z. Regn
Student Theses and Dissertations
In the global transition toward light emitting diode (LED) lighting, an understudied area is the impact on the culturing and testing of Whole Effluent Toxicity (WET) testing organisms, more specifically, the zooplankton species. Without comparison to the current lighting used for culturing and testing, it is unknown if there will be an impact on performance, which could affect effluent, regulatory, and product safety decisions. This dissertation investigated if culturing and reference toxicity testing using sodium chloride for Ceriodaphnia dubia, Daphnia magna, and D. pulex under LED lighting was comparable to fluorescent. Comparisons were made between two laboratories and by season, …
Efficacy Evaluation Of An Allopathic & Homeopathic Anthelmintic On Small Ruminant Parasite Loads, Kennon Leigh Harrington
Efficacy Evaluation Of An Allopathic & Homeopathic Anthelmintic On Small Ruminant Parasite Loads, Kennon Leigh Harrington
Student Theses and Dissertations
This study aimed to compare the efficacy of an allopathic and homeopathic anthelmintic in sheep and goats naturally infected with internal parasites. Animals with a threshold of ≥1000 EPG (n=30) were enrolled. The allopathic group received a single 14.79 mL per 50 lbs. BW drench solution of Prohibit®. The homeopathic group received a mixed herbal aqueous suspension, 2x/day D1-D3, thereafter 2x/day once a week W1-W4. There was an effect of anthelmintic treatment (P=0.0234) and day (P=0.0116) on total EPG, but no interaction effect for treatment by day (P=0.2440). For Initial sampling, there was a weak correlative tendency between weight and …
Protocol For Purifying And Sequencing Cell Subpopulations Based On Rna Fish Signal In Planaria, Mary Cathleen Mckinney, Jason A Morrison, Frederick G Mann, Dung M Vuu, Carolyn E Brewster, Kate E Hall, Blair W Benham-Pyle, Alejandro Sánchez Alvarado
Protocol For Purifying And Sequencing Cell Subpopulations Based On Rna Fish Signal In Planaria, Mary Cathleen Mckinney, Jason A Morrison, Frederick G Mann, Dung M Vuu, Carolyn E Brewster, Kate E Hall, Blair W Benham-Pyle, Alejandro Sánchez Alvarado
Faculty, Staff and Students Publications
Isolation and characterization of rare cell types in non-model organisms present a challenge. Here, we provide a protocol to purify specific cells from planaria for downstream RNA sequencing. We employ a one-step dissociation and fixation method that avoids RNA-degrading formaldehyde. We label cells using RNA fluorescence in situ hybridization (RNA FISH) and flow sort to enrich sequencing reads from cells of interest for deeper biological insight.
For complete details on the use and execution of this protocol, please refer to Mann et al.1
Neddylation Maintains Oocyte Quality By Stabilizing Mitochondrial Transcription, Avery A Ahmed, Tessa E Steenwinkel, Bethany K Patton, Peixin Jiang, Matthew D Meyer, Jaspreet K Rishi, Mei Leng, Alexander B Saltzman, Elizabeth S Anaya, Momal Sharif, Laurie J Mckenzie, Laura Detti, Anna Malovannaya, Sean M Hartig, Stephanie A Pangas
Neddylation Maintains Oocyte Quality By Stabilizing Mitochondrial Transcription, Avery A Ahmed, Tessa E Steenwinkel, Bethany K Patton, Peixin Jiang, Matthew D Meyer, Jaspreet K Rishi, Mei Leng, Alexander B Saltzman, Elizabeth S Anaya, Momal Sharif, Laurie J Mckenzie, Laura Detti, Anna Malovannaya, Sean M Hartig, Stephanie A Pangas
Faculty, Staff and Students Publications
Age-related decline in oocyte quality increases the risk of infertility, miscarriage, and birth defects. Mitochondrial dysfunction is a key contributor to this decline. Here, we report that oocyte-specific deletion of Uba3, which encodes the catalytic subunit of the E1 NEDDylation-activating complex, causes sterility in mice. Fully grown, germinal vesicle–stage Uba3 conditional knockout oocytes exhibit mitochondrial dysfunction, including elevated reactive oxygen species, impaired oxidative phosphorylation, and depletion of mitochondrially encoded RNA transcripts. Proteomic analysis identified alterations in mitochondrial-associated proteins, including enrichment of mitochondrial matrix and respiratory chain components and reduced abundance of electron transport chain complexes. These defects were associated …
Reproductive Trends Of Male Atlantic Spotted Dolphins (Stenella Frontalis) Following Two Hurricanes In The Bahamas, Tara Southerland Pedersen
Reproductive Trends Of Male Atlantic Spotted Dolphins (Stenella Frontalis) Following Two Hurricanes In The Bahamas, Tara Southerland Pedersen
USF Tampa Graduate Theses and Dissertations
Marine mammals are impacted by hurricanes that may influence reproductive success and genetic diversity. Understanding how populations respond to demographic change is increasingly important as extreme weather events become more frequent. A population of Atlantic spotted dolphins (Stenella frontalis) on Little Bahama Bank in the Bahamas has been observed continuously since 1985. In 2004, two hurricanes struck the region within one month, resulting in the loss of approximately 36% of the population. Population declines can alter the operational sex ratio (OSR), social structure, and encounter rates among potential mates, potentially influencing patterns of reproductive success. Previous molecular studies showed that …
Trophic Structure Of Reef-Fish Assemblages In The Eastern Gulf Of Mexico Varies By Depth And Reef Type, Jessica L. Van Vaerenbergh
Trophic Structure Of Reef-Fish Assemblages In The Eastern Gulf Of Mexico Varies By Depth And Reef Type, Jessica L. Van Vaerenbergh
USF Tampa Graduate Theses and Dissertations
Globally, marine ecosystems are increasingly threatened by anthropogenic stressors, leading to reef degradation, changes in reef-fish assemblages, and altered trophic structure. In this study, I investigated reef-fish underwater visual survey data collected over a decade (2013-2023) from paired natural and artificial reefs in the eastern Gulf of Mexico. I applied the novel Normalized Reef Status Index (NRSI) to evaluate how biomass was distributed across the three trophic categories (i.e., Lower Trophic Position (LTP; 2.0-2.9), Central Trophic Position (CTP; 3.0-3.9), and Upper Trophic Position (UTP; ≥4.0). This index is a metric to assess the ecological status of reef systems by investigating …
Development And Evaluation Of The East Florida Coastal Ocean Model (Efcom), Orion B. Scharton-Witmer
Development And Evaluation Of The East Florida Coastal Ocean Model (Efcom), Orion B. Scharton-Witmer
USF Tampa Graduate Theses and Dissertations
Florida’s Atlantic coast has abundant resources in beaches, state parks, aquatic preserves, and wildlife refuges as well as densely populated coastal cities in low lying areas that are all subjected to natural disaster threats from the oceans. There is an urgent need for a high-resolution coastal ocean circulation model for this region. Based on the application of the Finite Volume Community Ocean Model (FVCOM), an East Florida Coastal Ocean Model (EFCOM) is developed, downscaling from the deep ocean, across the continental shelf, and into the estuaries. It employs an unstructured grid with horizontal resolution varying from 3 kilometers at the …
Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal
Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal
The Thai Journal of Pharmaceutical Sciences
Animal research has played a major role in the development of vaccinations and therapies for illnesses such as tetanus, polio, meningitis, hepatitis, and Severe Acute Respiratory Syndrome Coronavirus 2. For every prescription drug available today, animal testing and research have contributed immensely. This narrative review aims to explore the contribution of animals to biomedical advancements in the current era, which involved a search of peer-reviewed literature using electronic databases such as Scopus, Web of Science, and PubMed. In current biomedical research, animals help develop new treatments for long-term illnesses such as cancer, HIV, and Alzheimer’s. Animals also aid in the …
Anti-Inflammatory Activities Of Muntingia Calabura L. In Monosodium Urate-Induced Acute Gout Arthritis: Regulation Of Nlrp3 And Il-1Β, Nita Parisa, Eva Rianty, Nia Savitri Tamzil, Debby Handayati Harahap, Veny Larasati, Bintang Arroyantri Prananjaya, Theodorus Theodorus
Anti-Inflammatory Activities Of Muntingia Calabura L. In Monosodium Urate-Induced Acute Gout Arthritis: Regulation Of Nlrp3 And Il-1Β, Nita Parisa, Eva Rianty, Nia Savitri Tamzil, Debby Handayati Harahap, Veny Larasati, Bintang Arroyantri Prananjaya, Theodorus Theodorus
The Thai Journal of Pharmaceutical Sciences
Background: Acute gout arthritis, which is caused by hyperuricemia, is a common inflammatory joint disease, leading to monosodium urate (MSU) crystal deposition. These crystals trigger inflammation, causing pain and significantly impairing the patient’s quality of life. Colchicine is commonly used to treat and prevent acute gout arthritis, but it has several side effects. Cherry tree (Muntingia calabura L.) leaves, which possess anti-inflammatory properties, show promise as an alternative treatment. The potential benefit of the leaves may be due to the flavonoid content.
Objectives: This study aimed to assess the anti-inflammatory activities of cherry tree leaves in an MSU-induced acute …
Microwave-Assisted Extraction Optimization And Bioactivity Assessment Of Flavonoid-Rich Extract From Lantana Camara L. Leaves In Zebrafish Epilepsy Model, Prem Kumar B R, Shwetha Krishnamurthy, Gouri Nair, Sundara Saravanan Kamatchi
Microwave-Assisted Extraction Optimization And Bioactivity Assessment Of Flavonoid-Rich Extract From Lantana Camara L. Leaves In Zebrafish Epilepsy Model, Prem Kumar B R, Shwetha Krishnamurthy, Gouri Nair, Sundara Saravanan Kamatchi
The Thai Journal of Pharmaceutical Sciences
Background: Lantana camara L. (Verbanaceae) is known for its bioactive compounds and has been reported for its potential therapeutic applications. Flavonoids from natural sources are acknowledged for their antioxidant and neuroprotective properties, suggesting a possible role in seizure management.
Objectives: This study intended to optimize the microwaveassisted extraction (MAE) of flavonoid-rich extract from L. camara L. leaves utilizing a designof- experiment approach and evaluate its antiepileptic property using the zebrafish model.
Materials and Methods: Four solvents (ethyl acetate, acetone, ethanol, and water) were initially used, with ethanol yielding the highest total flavonoid content (TFC). A central composite design was employed …