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Evaluation Of Il-17/Il-23 Axis In Iraqi Patients With Essential Hypertension, Fatima Jalal Ayez, Manal Mohammed Kadhim

Al-Qadisiyah Medical Journal

Background: Essential hypertension is a multifactorial disorder and a major global public health concern. Emerging evidence suggests that chronic low-grade inflammation plays a key role in its pathogenesis. The interleukin-17/interleukin-23 (IL-17/IL-23) axis has been identified as a critical inflammatory pathway linking immune activation to vascular dysfunction and elevated blood pressure. Aim of study: Evaluate the IL-17/IL-23 axis including the levels of IL-17A and IL-23 in patients with essential hypertension and to investigate their potential role as inflammatory biomarkers. Patients, Materials and Methods: A case-control study was conducted in Al-Diwaniyah Governorate, Iraq, from October 2025 to February 2026. The study …

Three Centuries Of Technological Innovation, Jordan G. Okie, James H. Brown, Astrid Kodric-Brown, Joseph R. Burger, Tatiana P. Flanagan, Trevor S. Fristoe, Sean T. Hammond, Norman Mercado-Silva, Jeffrey C. Nekola, Jennifer Richter

Biology Faculty Publications

What socioecological conditions nurture the ingenuity and collaborative interactions underlying transformative technological innovations? We compiled a dataset on more than 400 major technological inventions from 1690 to 1990 spanning seven categories (agriculture, armaments, information and communication, household, industry, medical, and transportation) and performed inductive macroecological analyses to address how attributes of inventors, teams, and their social and geographic environments contributed to the innovation of new technologies that have changed the way people live. The vast majority of inventions were attributed to single inventors of various ages. The frequency, size, and cultural diversity of teams increased in the 20th Century, as …

Tier 2 Monitoring In The Great Bay Estuary, Nh/Me Field Season 2025, Christopher Whitney, Amanda Giacchetti, Lara M. Martin, Trevor Mattera, Kalle Matso, David M. Burdick, Thomas K. Gregory

PREP Reports & Publications

No abstract provided.

Association Between Cooking Fuel Type And The Incidence Of Acute Respiratory Infections In Toddlers In Indonesia: A Cross-Sectional Study Based On 2017 Sdki Data, Ghina Puspa, Meiravigliosi Hermawan, Nuha Rafida Yumna

Jurnal Nasional Kesehatan Lingkungan Global

Acute Respiratory Tract Infection (ARI) remains a major health problem among toddlers in Indonesia and is closely related to exposure to indoor air pollution. This study aims to analyze the relationship between the type of cooking fuel used by households and the incidence of ARI in toddlers in Indonesia. The study used a cross-sectional design based on data from the 2017 Indonesian Demographic and Health Survey. The study sample included 196,804 respondents who met the inclusion criteria, namely having complete information on the type of cooking fuel and ARI symptoms. The independent variable was the type of cooking fuel divided …

Context-Specific Legitimacy In English Language Teaching: Rethinking Nativeness In The Korean Efl Context, Kenn Arcenal, Teri An Joy G. Magpale

Journal of English and Applied Linguistics

Although non-native English-speaking teachers now make up the majority of the global ELT workforce, perceived nativeness continues to function as an enduring filter in hiring and evaluation. This perspective paper examines how that filter operates unevenly across the institutional sectors of South Korea’s EFL labor market, arguing that Filipino English Teachers (FETs) face a distributive rather than a uniformly ideological inequity, with the biggest disadvantage concentrated in commercially driven private academies. Drawing on two companion studies of FETs working across Korean academic sectors (Magpale & Arcenal, 2025, in press) and integrating more recent scholarship on native-speakerism with comparative evidence from …

Clinical Interactions Of Celiac Disease And Relationship With Type 1 And Type 2 Diabetes Mellitus, Noor Thair Tahir, Raghda Shams Akram, Aseel Ibrahim Abbas, Sahar Abdul Wahab Alshaban, Fatma Abd Alhamza Obed

Al-Esraa University College Journal for Medical Sciences

Celiac disease is a typical autoimmune ailment that can be brought on by gluten, a protein present in wheat, barley, and rye. It is estimated that one person out of every 100 worldwide has celiac disease, with the majority going untreated. Although it can manifest asymptomatically, celiac disease is typified by a variety of gastrointestinal and extra-intestinal symptoms. The consistency of clinical, serological, and histopathological data is essential for the diagnosis of celiac disease. The diagnosis, nevertheless, is often missed and can be difficult. A higher risk of complications and a negative impact on quality of life are linked to …

Mpox Preparedness And Pandemic Memory: An Exploratory Study Among Young And Highly Educated Populations In Iraq, Israa M. Ali Alameen

Al-Esraa University College Journal for Medical Sciences

No abstract provided.

Determination The Prevalence Of Multidrug Antimicrobial Resistance Of Nosocomial Enterobacter Cloacae Isolates From Clinical Specimens In Baghdad Hospitals, Baidaa Mijbel Ali

Al-Esraa University College Journal for Medical Sciences

Background: Enterobacter cloacae have challenged global health through nosocomial infections, especially among immunocompromised patients. In the most overburdened healthcare systems, more study and strategy are anticipated. Aim of the study: To determine the prevalence of Enterobacter cloacae in hospital-acquired infections in Baghdad hospitals and to evaluate its antimicrobial resistance patterns across burn, wound, and urine samples, with a focus on multidrug resistance and antibiotic resistance trends. Methods: Three hundred and seventy-seven patient samples were collected and examined at a teaching laboratory in Baghdad between January 2024 and December 2024. These had 513 samples, 238 burn swabs, 139 wound swabs, and …

From Tragedy To Liberation: The Tragic Mulatta And Abolition Democracy At The Intersection Of Race And Gender In The Quadroons And The Octoroon, Maram Mohammed Mahmoud Samman

University of Tabuk Journal for Humanities and Social Sciences

This essay explores the figure of the tragic mulatta in Lydia Maria Child’s The Quadroons and Dion Boucicault’s The Octoroon, analyzing how mixed-race female characters critique the racial and gender hierarchies of 19th-century America. Using an intersectional lens, it examines how race, gender, and class shape the identities and tragic fates of Xarifa and Zoe—women who were socially excluded from both Black and White communities. Drawing on W.E.B. Du Bois’s concept of double consciousness and the framework of Abolition Democracy, the essay argues that the tragic mulatta is not merely a narrative trope but a site of political tension and …

Clinical Epidemiology Of Stroke In The Productive Age Population In Indonesia: A Scoping Review, Satria Akbar Putra Asmara, Ulil Albab Habibah

Jurnal Epidemiologi Kesehatan Indonesia

Data from the 2018 Indonesian Basic Health Research (Riskesdas) demonstrates a marked increase in stroke prevalence, rising from 7% in 2013 to 10% in 2018. This upward trend is accompanied by a notable epidemiological shift, with stroke no longer predominantly affecting older adults ≥65 years, but increasingly occurring among the productive-age population (15–64 years). This scoping review was conducted in February 2026 in accordance with the JBI methodological guidelines and PRISMA-ScR. Searches were conducted in Google Scholar, PubMed, Garuda, and ScienceDirect. Inclusion criteria include articles published within the last 10 years (2016–2026), articles discussing the characteristics of stroke patients in …

Sexuality-Related Lexical (In)Visibility In Asian Englishes: A Corpus-Based Study Using The International Corpus Of English (Ice), Jess V. Mendoza, April N. Salvador, Teri An Joy G. Magpale

Journal of English and Applied Linguistics

This study examines the visibility and invisibility of sexuality-related terms in four Asian Englishes using data from the International Corpus of English (ICE). Drawing on Wilkinson’s (2022) sexuality-related lexical set and informed by scholarship on heteronormativity, the study analyzes the proportional visibility of 19 target lexemes across Englishes in Hong Kong, the Philippines, Singapore, and India. The findings show that only a small subset of terms (gay, lesbian, same sex, sexual preference, bisexual, and sexual orientation) appear in the corpora, and even these occur at low frequencies. Among these, gay emerges as the most recurrent. The remaining terms are not …

Binara: A Game-Based 3d Simulation Framework For Pre-Occupancy Architectural Design Evaluation, Doaa Sinnari

Journal of King Abdulaziz University: Computing and Information Technology Sciences

Architectural design workflows still rely heavily on post-occupancy evaluation (POE), where usability and experiential issues are often identified only after buildings have been constructed. Although advances in real-time rendering and game engines enable immersive architectural visualization, most existing tools primarily support passive walkthroughs and remain disconnected from systematic user-experience evaluation. This limitation highlights the need for interactive approaches that allow stakeholders to experience and assess architectural spaces prior to construction. This paper presents Binara, a game-based three-dimensional simulation framework designed to support immersive pre-occupancy architectural design evaluation. The proposed framework integrates architectural construction tools, immersive walkthrough exploration, and conversational feedback …

Examining The Effects Of Interdependent Group Contingencies As A Classwide Intervention To Reduce Unsafe Behavior On The Playground, Elizabeth K. Linton

LSU Doctoral Dissertations

The purpose of this study was to evaluate the effects of different class wide interdependent group contingencies on unsafe playground behavior and student preferences for each intervention. In Experiment 1, we assessed the effects of the Good Behavior Game (GBG) on unsafe behavior across three third-grade classes. The GBG effectively reduced unsafe playground behavior relative to baseline, though student-choice data indicated that students did not prefer the intervention. This finding prompted Experiment 2, in which we evaluated synchronous schedule of reinforcement (SSR) as a classwide interdependent group contingency and compared its effectiveness and preference to the GBG. Participants in Experiment …

Immersive Virtual Reality For Enhancing Learning Of Transport Phenomena In Undergraduate Chemical Engineering, Muhammad Nawaz, Afiq Mohd Laziz, Kok Keong Lau, Bawadi Abdullah, Ratri Rahmawati

Platform: A Journal of Engineering (PAJE)

```python text = """As experiential learning becomes more central to engineering education, immersive technologies such as virtual reality (VR) are emerging as transformative tools for delivering abstract and spatially intensive subjects. This study investigates the effectiveness of a custom-designed VR for enhancing student understanding of transport phenomena (TP) concepts in undergraduate chemical engineering education. A mixed-method evaluation involving 160 students from the Chemical Engineering Department, Universiti Teknologi PETRONAS (UTP), Malaysia, was conducted using pre\x02and post-intervention surveys. Likert-scale ratings and word cloud analyses were used to assess perceived conceptual gains, usability, engagement, and perceived instructional value. Findings reveal that 85.6% of …

The Development Of An In Silico Vaccine Design-Based E-Module To Improve Students' Biological Literacy, Qairinasherin Qwine Ferendi, Rusdi Rusdi, Hanum Isfaeni

Jurnal Pendidikan Sains

Low levels of biological literacy among students, particularly in biotechnology, highlight the need for innovative digital learning media that facilitate meaningful and contextual learning experiences. This study aimed to develop and evaluate an interactive biotechnology e-module based on in silico vaccine design to improve students’ biological literacy. The study employed Educational Design Research (EDR) using the Hannafin and Peck model, which consists of three phases: needs assessment, development, and implementation. The participants included 73 tenth-grade science students and one biology teacher from SMAN 68 Jakarta, Indonesia. The e-module was developed using Canva and Heyzine to create an interactive flipbook integrating …

Lesson-1 On Mni Wiconi (Water Is Life): Understanding The Problem Of Water Contamination, Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students investigate a scenario of water contamination in a fictional community. They define the engineering problem of dirty water and explore the cultural and ecological significance of water through the lens of indigenous principles. This lesson introduces students to the concept of water contamination and the need for purification, grounding the learning in a real-world problem and connecting to Indigenous knowledge about the land and water.

Problem-Based Learning (PBL) Scenario: Students receive a letter from a fictional community whose water source has become cloudy and is making people sick. They are tasked with becoming “Water Engineers” to investigate the …

Lesson-2 On Mni Wiconi (Water Is Life): Designing And Testing Solutions (Water Filtration), Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students apply the engineering design process to build, test, and refine a simple water filter prototype. This hands-on experiential learning activity focuses on the properties of filtering materials and iterative problem-solving.  In this lesson, students will apply the engineering design process to build and test their own simple water filters. They will use their newfound knowledge to begin developing a practical solution to the problem presented in Lesson 1 - Mni Wiconi: A Water Engineering Challenge for 4th Graders.

Problem-Based Learning (PBL) Scenario: Having identified the problem, students are now tasked with designing and building a prototype water filter …

Developing Biodegradable Packaging Films And Beads From Agricultural Residues, Sandeep Paudel, Santosh Rijal, Srinivas Janaswamy, Madhav P. Nepal

iLEARN Teaching Resources

Agricultural waste is produced in large amounts worldwide. These are often discarded despite being valuable sources of cellulose and renewable, biodegradable products. At the same time, rising environmental concerns about petroleum-based plastic packaging have created demand for sustainable alternatives. Introducing K-12 students to biodegradable packaging materials developed from agricultural waste can enhance understanding of sustainability, basic materials science, and circular bioeconomy concepts while encouraging interest in STEM fields. Another concern is the presence of microplastics and nanoplastics in drinking water, which can pose serious risks to human health. Traditional coagulation agents, such as ferric and aluminum salts, are less effective …

Anthropology 230 "Culture And Crime": Syllabus, Assignments And Brightspace Quiz Files, Eliza Darling

Open Educational Resources

As part of a project to convert online asynchronous sections in John Jay’s fully online program to OER, Dr. Eliza Darling compiled all of her materials for a 200-level anthropology course, “Culture and Crime,” into a single PDF that can be easily converted to other file types. The assignments and lessons make frequent use of open pedagogical principles. Dr. Darling has also included 14 quizzes as ZIP files that can be imported directly into any LMS, including Brightspace, Canvas, and Blackboard. Because these quizzes are already packaged for LMS import, instructors can add them directly to a course shell without …

Lesson-3 On Mni Wiconi (Water Is Life): Analyzing Evidence And Communicating Solutions (Community Stewardship), Reycel Jugo, Madhav P. Nepal

iLEARN Teaching Resources

Students analyze the data collected from their filter tests, construct an evidence-based argument for their most effective design, and communicate their solution to a “community council” (the class), connecting their technological solution back to community well-being. In the final lesson, students will analyze their data, draw conclusions, and communicate their findings. They will present their improved water filter designs to the class, acting as consultants for the fictional community.

Problem-Based Learning (PBL) Scenario: Students are now ready to present their final water filter prototypes and a summary of their findings to a “community council” (the rest of the class). They …

The Multifaceted Medicinal Properties Of Momordica Charantia: Insights Into Phytochemistry And Therapeutic Applications, Maham Ashfaq, Haroon Ur Rashid, Javaria Ashfaq, Shazia Ramzan, Fatma Hussain

Journal of Bioresource Management

Momordica charantia (bitter melon) is a significant medicinal plant, having been long used in traditional medicine in Asian, African and South American systems. M. charantia is more than a traditional medicine; by consolidating existing evidence, it is a promising source of drug discovery and can serve as a complementary in contemporary therapeutics. Over the last several decades, it has become the subject of contemporary biomedical studies due to its abundance of phytochemicals, such as saponins, flavonoids, alkaloids, and polypeptides. These bioactive compounds present a wide range of pharmacological processes that M. charantia can be a natural solution to some of …

Anti-Photoaging Activity Of Kombucha Coffee (Coffea Canephora) Extract Antioxidant Moisturizer On Ultraviolet-B Induced Malondialdehyde In Mice Skin, Renata Prameswari, Lifia Chandra, Dian Ardiana

Folia Medica Indonesiana

Photoaging caused by chronic sun exposure exhibits characteristics similar to intrinsic aging, including skin thinning, moisture loss, roughness, collagen degradation, and wrinkle formation. This process is driven by oxidative stress and the formation of malondialdehyde (MDA) as a result of lipid peroxidation. Topical intervention using antioxidant-based moisturizers could prevent further damage. Robusta coffee (Coffea canephora), high levels of chlorogenic acid and caffeine, is known for its antioxidant properties. When fermented with a Symbiotic Culture of Bacteria and Yeast (SCOBY) to produce kombucha coffee, its bioactive compounds are enhanced, potentially offering additional protection against oxidative stress and photoaging. This …

The Inflammatory Link Between Obesity, Quality Of Life, And Female Sexual Dysfunction: The Role Of Interleukin-6, Amelia Putri Ariyani, Lilik Herawati, Zidni Imanurrohmah Lubis, Alifia Syafira Putri, Adhiratih Ken Sari

Folia Medica Indonesiana

Female sexual dysfunction (FSD) is a common condition that impairs women's quality of life and is frequently associated with obesity. Beyond hormonal and vascular mechanisms, chronic low-grade inflammation, particularly elevated interleukin-6 (IL-6), has been proposed as a biological mediator of this association. This systematic review, registered in PROSPERO (CRD420251046082), aimed to evaluate the role of IL-6 in mediating the association between obesity and FSD. A comprehensive search of PubMed, Scopus, Embase, and Web of Science was conducted for studies published between 2018 and 2025, focusing on obese women, quantitative IL-6 measurements, and validated assessments of sexual function such as the …

Comparative Screening Of Cytotoxic Potential Of Berberis Aristata And Senna Alexandrina Extracts, Rida Noor Akhtar, Javaria Zahoor, Rizwan Ullah Khan, Aziz Ullah, Naila Malkani

Journal of Bioresource Management

Medicinal plants provide a safe and efficient source of drugs for cancer treatment. Berberis aristata and Senna alexandrina are traditionally used to treat several ailments because they contain compounds with antimicrobial, antitoxic, anti-inflammatory, and other properties. The objective of the study was to prepare crude ethanolic extracts of B. aristata and S. alexandrina and to determine their cytotoxic potential against cancer cells. Ethanolic extracts were prepared for both plants. Hepatocellular carcinoma cells (HepG2) were used for all assays. The cytotoxicity of extracts was determined by 3‑(4,5‑Dimethylthiazol‑2‑yl)‑2,5‑diphenyltetrazolium bromide (MTT) assay using various concentrations of extracts. The obtained sub-lethal concentrations were used …

Nanotechnology In Wound Healing And The Rising Role Of Bionanocomposites, Humaira Yasmeen, Saher Mahmood, Iqra Munir, Hubza Ruatt Khan, Iram Asim, Abeera Abid, Kashaf Junaid, Asif Raheem, Sara Janiad

Journal of Bioresource Management

Nanotechnology holds considerable promise in the field of biomedical research, particularly in the creation of innovative materials. Its influence extends significantly to medication formulation, drug delivery systems, and the realm of nanomedicine. These materials are being increasingly investigated for a range of applications; nevertheless, it is essential to conduct thorough assessments of their safety and environmental implications. Globally, millions of people suffer from slow wound healing, which leads to heightened mortality rates and escalated healthcare expenses. The primary factors contributing to impaired wound healing include microbial infection, unstable inflammation, and persistent inflammation. Regrettably, these critical issues have not been adequately …

Effect Of High Protein Diets On Kidney Health Among Athletes And Bodybuilders With Normal Kidney Function, Mustafa Mehdi Alqazzaz, Sajad Abdullah Jleep, Nouran Hussein Mutlaq, Ali Jabbar Jassem

Al-Esraa University College Journal for Medical Sciences

This study emphasizes the effect of high-protein diets(HPD) on kidney function, focusing on key biomarkers (Albumin, Urea, Creatinine & GFR). A HPD is defined as a protein consumption >1.5g/kg per day. Results indicated variations in certain biomarkers among the participants (healthy athletes & bodybuilders with normal kidney function) suggesting potential changes in renal workload. Many studies in resistance-trained athletes focusing at HPD, concluded that there are no harmful effects of HPD on renal health. While no immediate kidney damage was observed, we suggest further investigation into the long -term implications of HPD, particularly for individuals with specific health conditions.

Measuring The Concentration Of Heavy Metals In The Serum Of Traffic Police And Their Impact On Heart Disease In The Future, Hanaa Khalil Sacheat

Al-Esraa University College Journal for Medical Sciences

The spread of heavy metals such as lead, cadmium and nickel is a clear danger that threatens the earth and disrupts the ecological balance. In this research, we evaluated the danger of these metals present in the areas of traffic points for traffic policemen who are present for long periods at traffic points. 25 blood samples were collected from traffic policemen present at traffic points, with information about age, date of joining the job, and smoking, The comparison was made with the same number of samples of people who were in a job inside buildings, The results showed a significant …

Crispr/Cas9-Based Genome Editing: Understanding Differences In Dna Repair Pathways, Profiles, And Outcomes, Samuel Effah, Shirley Barrera, Nahia Urturi Ortiz, Will Dampier, Michael Nonnemacher, Brian Wigdahl

Kimmel Cancer Center Faculty Papers

Over a decade of advances in Clustered Regularly Interspersed Short Palindromic Repeats (CRISPR) and CRISPR-associated protein 9 (Cas9)-based technologies have culminated in the first-ever FDA-approved CRISPR/Cas-based therapy. Aside from this approved therapy for sickle cell anemia, several CRISPR/Cas-based therapies are currently under development or testing for a range of chronic diseases, including viral diseases like human immunodeficiency virus type 1 (HIV-1) infection, genetic diseases like familial hypercholesterolemia, and cancer. The success of these therapies hinges on the effective delivery of CRISPR/Cas9 components to target regions, efficient Cas endonuclease editing, repair profiles generated, and their resulting outcomes. Here, we discuss the …

An Interactive Multi-Objective Programming Approach For Optimizing Fully Trapezoidal Spherical Fuzzy Linear Programming Problem With Application, Sultan S. Alodhaibi, Hissah Ibrahim Almuzini, Hamiden Abd El-Wahed Khalifa

Neutrosophic Systems with Applications

In this paper, a linear programming framework with completely uncertain parameters is investigated by employing trapezoidal spherical fuzzy numbers (TrSFNs). The proposed formulation incorporates a spherical fuzzy (SF) decision environment in which the optimization process simultaneously maximizes the degree of positive membership while minimizing the corresponding neutral and negative membership degrees. By utilizing the concept of the α -cut associated with TrSFNs, the original fully fuzzy linear programming problem is transformed into an interval-valued linear programming model with confidence levels. To rank and compare the resulting interval objective values, an interval ordering approach based on the decision maker's preferences—considering the …

Vitamin C (Ascorbic Acid) Supplementation In Caprine Semen Extenders: Current Evidence, Knowledge Gaps, And Implications For Triladyl® Based Preservation Systems, Abdul Saboor Brohi, Qudratullah Kalwar, Muhammad Mohsen Rahimoon, Hidayatullah Soomro, Hubdar Ali Kolachi, Rafique Ahmed Shar, Muhammad Awais Soomro, Abdul Aleem Korejo, Muhammad Arslan Yousaf Rehan, Sajad Ali Laghari

Journal of Bioresource Management

Cryopreservation of goat semen is an essential tool for genetic improvement, germplasm conservation, and the expansion of artificial insemination programs in caprine breeding. However, buck spermatozoa are highly susceptible to cryo-induced oxidative stress due to their membrane composition rich in polyunsaturated fatty acids. Excessive generation of reactive oxygen species during semen processing, freezing, and thawing compromises sperm motility, viability, membrane integrity, mitochondrial function, and DNA stability, ultimately reducing post-thaw fertilizing potential. Semen extenders play a pivotal role in mitigating these detrimental effects by providing cryoprotection and maintaining cellular homeostasis. Among commercial extenders, Triladyl® is widely used in ruminant semen preservation; …