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Physiologically Derived, Per-Control Input Debouncing For Tremor-Affected Touch And Key Input, Gerard Ziemski

Defensive Publications Series

This disclosure describes an accessibility technique, making no health claim: filtering the unintended repeated activations caused by hand tremor from discrete user input, deriving the rejection window from the physiology of the tremor rather than choosing it by feel or exposing it as a user setting.

A tremor at frequency f spaces its repeats approximately 1/f apart. The method sets the debounce window to one full tremor period, W = 1/f, and makes explicit the rule that follows: a window W rejects every repeat sooner than W, and so suppresses every tremor faster than 1/W. The uncovered edge is therefore …

Transfemoral Approach To Patent Ductus Arteriosus Occlusion Using Acdo In A Dog With Complex Surgical History, Nawat Sannamwong, Hataichon Owatdhumma, Kornrawee Tharavanij, Thitinan Tangarsasilp, Nardtiwa Chaivoravitsakul, Kongthit Horoongruang, Patmanachatr Bunnag, Nakkawee Saengklub, Krishaporn Kradangnga, Sirilak Disatian Surachetpong, Anusak Kijtawornrat

The Thai Journal of Veterinary Medicine

A five-year-old spayed female Welsh Corgi weighing 12.4 kg presented with exercise intolerance and was diagnosed with a patent ductus arteriosus (PDA). Due to signs of left-sided volume overload, the dog was initially managed with oral pimobendan and was subsequently referred to the Small Animal Teaching Hospital at Chulalongkorn University for further evaluation and intervention. Upon presentation, the patient was bright, alert, and responsive, with a body condition score of 6 out of 9 and normal muscle condition. The mucous membranes were pink and moist, with a capillary refill time of 1 to 2 seconds. A continuous heart murmur was …

Evaluating The Potential Of Cajanus Cajan (L.) Millsp. Root To Improve Atopic Dermatitis With Different Anti-Inflammatory Models And Active Compounds, Shu-Er Yang, Xiang-Ming Cai, Yu-Wen Chu, Jen-Chieh Tsai, Mey-Fann Lee, Tuzz-Ying Song

Journal of Food and Drug Analysis

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent bacterial infections that cause pruritus, erythema, xerosis and thickening. Cajanus cajan root extract prepared with 95% ethanol (EECR95) has been shown to possess antioxidant, anti-inflammatory, and antibacterial properties in previous studies. This study aimed to evaluate EECR95’s ability to improve AD by inhibiting methicillin-resistant Staphylococcus aureus (MRSA) growth and reducing inflammation. This study found EECR95 effectively inhibits MRSA growth (IC₅₀ = 103.74 μg/mL) and reduces pro-inflammatory cytokine production in an MRSA-keratinocyte-macrophage model. LC/MS/MS analysis revealed the presence of active compounds- flavonoids, isoflavones, and flavonoid glycosides, highlighting EECR95's potential …

The Defining Role Of Ago4 And Its Catalytic Activity During De Novo Rna-Directed Dna Methylation, Tianyi Li

Arts & Sciences Graduate Student Theses and Dissertations

Plant transposable elements and transgenes are continuously targeted for transcriptional repression via the pathway of RNA-directed DNA methylation (RdDM). Although perpetual RdDM of the endogenous genomic loci has been well studied in the field, much less is known about the de novo RdDM pathway, the pioneering round of DNA methylation responsible for triggering and initiating silencing of new transgenes. Despite being two distinct pathways, both perpetual and de novo mechanisms of RdDM require the production of small interfering RNAs (siRNAs) and the key proteins of the ARGONAUTE4 (AGO4) clade. However, the order and likely mechanism of recruitment of AGO4 to …

Interplay Between Patterning And Morphogenesis During Zebrafish Embryonic Development, Chia-Teng Chang

Arts & Sciences Graduate Student Theses and Dissertations

Patterning and morphogenesis occur concurrently during embryonic development. In many contexts, both processes are regulated by morphogen signaling: morphogens specify spatially organized cell identities while also influencing the cell behaviors that shape tissues. This creates a reciprocal problem. Morphogen signaling can affect how cells move, while cell movement can change how cells experience and interpret morphogen signals. This dissertation investigates this reciprocal problem during zebrafish gastrulation and neurulation. First, it examines how the ventral-to-dorsal bone morphogenetic protein (BMP) activity gradient regulates germ-layer morphogenesis during gastrulation. BMP signaling is known to pattern dorsal–ventral cell fate and regulate mesodermal convergence and extension …

Th17 Effector Cytokines Induce Shared And Distinct Microglial And Endothelial Cell Responses In A Mouse Model For Post-Streptococcal Encephalitis, Charlotte Wayne, Uğur Akcan, Travis Faust, Violeta Durán-Laforet, Danny Jamoul, Luca Bremner, Nicole Ampatey, Büşra Akcan, Sarah Ho, Bogoljub Ciric, Shannon Delaney, Wendy Vargas, Susan Swedo, Vilas Menon, Dorothy Schafer, Tyler Cutforth, Dritan Agalliu

Department of Neurology Faculty Papers

Group A Streptococcus (GAS) infections cause neuropsychiatric complications in children, but the mechanisms linking peripheral infection to brain dysfunction remain unclear. Using mouse genetics, single-cell RNA sequencing, and spatial transcriptomics, we show that GAS infections induce inflammatory transcriptional programs in microglia and brain endothelial cells (BECs), accompanied by loss of blood-brain barrier (BBB) gene expression in female mice. Spatial transcriptomic analyses reveal that GAS-responsive microglia localize near infiltrating CD4+ T cells. Several microglial chemokines induced in mice are elevated in sera from affected patients. Deletion of GM-CSF in CD4⁺ T cells partially reduces microglial chemokine gene expression, without restoring BBB …

Transient Activation Of Potent Progenitor Cells Is Required For Spinal Cord Regeneration, Chase Alexander Weinholtz

Arts & Sciences Graduate Student Theses and Dissertations

Mammalian spinal cord injury is an intractable biomedical problem driven by interlocking maladaptive cellular responses that prioritize acute stabilization over long-term recovery. However, this deficient regenerative capacity is not an inherent limitation. The zebrafish, for example, capably regenerates and regains motor function with 2 months of a full transection injury. This ability is thought to rely on the transient expansion of stem cell-like progenitors marked by sox2 expression. Yet our understanding of the identities and contributions of this crucial population remains limited. Here, we determine the molecular identities and cellular contributions of sox2+ progenitors during innate spinal cord repair in …

After A Fire: Considerations Of Personal Safety When Visiting Fire-Damaged Property, Andrew J. Whelton, Todd Thalhamer, Eric Bollens

Resilience to Emergencies and Disasters

No abstract provided.

Comparing Non-Invasive Survey Methods For Southern Flying Squirrels (Glaucomys Volans) At The Western Edge Of Their Range, Jay E. Winfield, Jeremy A. White

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The southern flying squirrel (Glaucomys volans) is a threatened species in Nebraska that occurs along the Missouri River in the southeastern corner of the state. Recently, a population was discovered in the city of Lincoln, but it is unknown whether this population represents a natural range expansion from the Missouri River population or whether it is isolated and results from a human-assisted movement. A survey of southern flying squirrels in Nebraska is needed, but surveys of this elusive species are challenging. This study investigated and compared two noninvasive survey techniques for rapid detection of flying squirrels: acoustic detectors …

Threads Of The Frightening: The Uncanny, Alienation, And Horror In Otsuichi's Fiction, Kathryn Lawhon Stephens

Arts & Sciences Graduate Student Theses and Dissertations

The “J-horror boom” of the 1990s and early 2000s saw the international success of films like Nakata Hideo’s Ring (1998), bringing considerable and laudable attention to Japanese horror in the realm of film and media studies. Yet even Ring’s Sadako, one of the most popular contemporary figures in Japanese horror, first appeared as a literary character years before her debut on screen. The average layperson’s unfamiliarity of such a famous horror icon’s literary origins illuminates the comparative lack of literature-centric scholarship on major writers and figures of Japanese horror that this dissertation seeks to rectify.

First interrogating the fluidity …

Co-Opting Modernity: The Semantic Retooling Of Faith At The 1893 World’S Parliament Of Religions, Erik P. Palmer

The Thetean: A Student Journal for Scholarly Historical Writing

The 1893 World’s Parliament of Religions in Chicago served as a high-stakes arena where the boundaries of religious legitimacy were redrawn through the intentional adoption of social science vocabulary. Staged within the Neo-Classical architecture of the White City of the World’s Columbian Exposition, the event was more than a civil gathering; it functioned as a “Museum of Faiths” where religious traditions were curated, categorized, and evaluated against the perceived benchmarks of Western civilization. The physical environment of the Fair, a monument to industrial triumph, was built to display things that worked. The organizers demanded that religions demonstrate they were useful …

Advanced Manufacturing And Materials Of A Bio-Mimetic Hoof For Space Robotics Applications, Benjamin Heckel

Discovery Day - Daytona Beach

Planetary surfaces often feature steep, uneven, and unpredictable terrain conditions that resemble some of the most challenging natural environments on Earth. In these terrestrial settings, certain animals have evolved to navigate complex landscapes with remarkable agility. One example is the mountain goat, an animal whose hooves have evolved for stable and precise movement across rocky, inclined surfaces. This biological adaptation provides a useful model for improving robotic mobility in planetary exploration. This study draws inspiration from that natural adaptation to develop a bio-mimetic robotic hoof designed to enhance traction, durability, and adaptability for extraterrestrial exploration. By replicating the mechanical properties …

A Qualitative Analysis Of Human-Ai Interaction Through Animated Shapes, Kavya Dipen Shah, Angel Hinojosa, Caroline Deck

Discovery Day - Daytona Beach

As technology becomes more advanced, it is important to understand how people perceive the intentions and abilities of machines. This project, conducted in the InTeRACT Lab, explores how we attribute humanlike qualities to different types of agents, ranging from animals to robots. The study analyzes data from an experiment where participants watched animations of moving triangles. Although the videos were identical, participants were told the shapes represented either humans, robots, dogs, or inanimate objects. While previous math-based data showed that these labels changed how people felt, those structured scales didn't allow for a natural, unbiased explanation of what people actually …

Social Attributions Of Moving Shapes: Comparing Qualitative Analyses Of Humans Vs. Ai, Angel Hinojosa

Discovery Day - Daytona Beach

As technology becomes more intelligent, the relationship between humans and machines is rapidly shifting. Whether a machine is perceived as a capable partner or a source of wariness often depends on the intentions and abilities, we attribute to it. My research in the InTeRACT Lab seeks to empirically assess these perceptions by comparing how we view different nonhuman agents, ranging from animals to robots.   This study analyzes qualitative data from a task where participants viewed animations of moving triangles. While the videos remained the same, participants were told the shapes represented either humans, robots, dogs, or inanimate shapes. Previous quantitative …

Phaëthon System, Brady Roudabush, Lauren Gallo, Emelia Thompson, Jacob Woods

Discovery Day - Daytona Beach

Phaëthon System is the project name for the Search and Rescue Drone Initiative. This initiative will improve the current search and rescue drone industry by introducing new techniques to get through dense forest canopies and other places where an overhead view is not useful. The Phaëthon System uses a swarm of drones that can penetrate under the tree canopy to map and search with the utmost efficiency and safety for rescuers. A command drone is launched to survey the overall search area, and set up a communications and data link. The next component is then released, which is a swarm …

From Sunscreen To Seafood: Tracing The Ecological And Human Health Risks Of Oxybenzone Contamination In Local Fish, Alyssa Brasko

Discovery Day - Daytona Beach

Oxybenzone (benzophenone-3) is a widely used ultraviolet (UV) filter in sunscreens, offering protection against harmful radiation but raising significant environmental concerns due to its persistence and toxicity in aquatic ecosystems. This ongoing study aims to investigate the bioaccumulation and ecological impact of oxybenzone in fish species along Florida’s Space Coast, contributing to a broader understanding of its environmental fate and potential human exposure through seafood consumption. The research will employ advanced analytical techniques, including Gas Chromatography-Mass Spectrometry (GC-MS) and High-Performance Liquid Chromatography (HPLC), to quantify oxybenzone levels in locally sourced fish. Fish samples will be obtained from the non-profit organization …

Accelerating Search And Rescue Response: A Simulation Study On The Dynamic Efficiency Of Flocking-Enabled Drone Swarms, Sophia Beckwith, Carys Del Prete

Discovery Day - Daytona Beach

This project explores how imitations observed in animal group behavior, specifically flocking in birds, can be applied to the functionality of autonomous drone systems to aid in search and rescue efforts. The goal is to demonstrate how incorporating code based on the Boids, Vicsck and predictive control linear algebraic mathematical models for drone flight controls and the collective behaviors of flocks will increase the efficiency of drone maneuvers, allowing them to reorganize and fill gaps when one is removed. A MATLAB-based simulation was developed to model the behaviors using research conducted on the symmetric and synchronized behaviors observed from flocks …

Numerical Investigation Of The Nonlinear Simple Pendulum And The Dependence Of Oscillation Period On Initial Angle, Kelly Wold, Aidan Hart, Patrick Gilliam

Discovery Day - Daytona Beach

Numerical Investigation of the Nonlinear Simple Pendulum and the Dependence of Oscillation Period on Initial Angle examines how the oscillation period of a simple pendulum varies with initial angular displacement and evaluates the accuracy of numerical methods in capturing this behavior. In classical treatments, the small-angle approximation simplifies the governing differential equation and predicts a constant period independent of amplitude; however, this assumption breaks down for larger angles, where the system exhibits nonlinear dynamics. The objective of this project is to model the full nonlinear equation of motion and quantify how the period depends on initial conditions. To achieve this, …

Book Review: Cold War On Five Continents, Sviatoslav Kozlov

History in the Making

No abstract provided.

The Impact Of Technology On The Chinese Queer Community, Samantha Collasco

History in the Making

This project’s aim is to analyze the various ways in which the internet has influenced the Chinese LGBTQ+ community. The Chinese government has created an immense censorship over the community and any accompanying terms, therefore leading to their discrimination and marginalization within Chinese society. How has queer representation changed in China since the decriminalization of homosexuality? How has the internet affected the public perception of the LGBTQ+ community? What role does censorship play in the shaping of public perception of queer identities? How has westernization and globalization affected the attitudes towards queer identities? This work engages with the existing scholarship …

The Shorthorn: August 1, 1984

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

Behavioral Effects Of Novel Treatments For Pain Management Using Combinatorial Methods, Rohit Rajeev Nambiar

Theses and Dissertations

Pain, despite being an uncomfortable feeling to experience, is a necessary protective mechanism for the body1. Understanding that pain results from several different mechanisms within the body is important to discovering the optimal way to treat and manage a person’s pain. Modern medicine has seen numerous advancements in treating or managing acute and chronic pain, particularly with opioid drugs. However, these treatments come with potential side effects, including opioid use disorder (OUD) and fatal overdose. Finding new treatment methods, or improving existing methods, is crucial for patients with pain. This thesis explores two projects looking to develop safer analgesia using …

Experience Of Using Rho Kinase Inhibitor Eye Drops In Corneal Edema At Tertiary Care Hospital In Thailand, Pakornkit Phrueksaudomchai, Aekchanok Watcharapanjamart, Ploypak Thanakroekkiat

Asian Medical Journal and Alternative Medicine

Purpose: This study aimed to evaluate the experience of using Rho kinase inhibitor eye drops in corneal edema.

Setting/Venue: Thammasat University Hospital, Thailand

Methods: This retrospective longitudinal cohort study included patients with corneal edema treated with topical ripasudil. Clinical data were collected from medical records, including diagnosis, demographic characteristics, dosage regimen, and outcomes such as visual acuity (VA), intraocular pressure (IOP), central corneal thickness (CCT), endothelial cell count (EEC), coefficient of variation (CV), and percentage of hexagonal cells (%Hexa). Patients were followed across multiple visits (Visit 0-5). Subgroup analyses were performed according to underlying etiologies.

Results: 46 eyes of 46 …

Melatonin In Pediatric Critical Care: From Physiology To Bedside Roles, Chanapai Chaiyakulsil

Asian Medical Journal and Alternative Medicine

Melatonin is an endogenous indoleamine synthesized by the pineal gland. Though melatonin is best known for its chronobiologic effects, regulating the circadian rhythm and sleep, it might play a wider role in critical illness. It has been proposed for use as an analgesic and sedative, an antihypertensive, an anti-inflammatory, and for the prevention of delirium. Melatonin use in children has increased dramatically over the years, but the evidence on its use in critically ill children remains limited. This review article aimed to describe the basic physiology and biology of melatonin, including its production and functions, dosing, and side effects, …

Analyzing The Transition From Writing Center Tutor To Graduate Student Instructor, Luci Mackenzie Sullivan

Theses and Dissertations

Writing center tutoring is almost universally considered to be beneficial preparation for graduate student instructors (GSIs) of writing, so much so that many programs require writing center experience as part of their GSI training. Despite various similarities between the roles of tutor and teacher, the precise ways in which writing center experience influences GSIs as teachers remain unclear. This IRB-approved, mixed-methods study builds on previous empirical scholarship on transfer between tutoring and teaching to determine how new GSIs with previous writing center experience integrate practices, knowledge, and dispositions developed in the writing center. My findings echo those of previous studies …

Malt1 Protease Inhibition Restrains Glioblastoma Progression By Reversing Tumor-Associated Macrophage-Dependent Immunosuppression In Mice, Juliana Hofstätter Azambuja, Saigopalakrishna Yerneni, Lisa Maurer, Hannah Crentsil, Gabriela Debom, Linda Klei, Mei Smyers, Chaim Sneiderman, Kristina Schwab, Rajesh Acharya, Aivi Nguyen, Josie Emery, John Little, Jeffrey Meridew, Yijen Lin Wu, Prasanna Ekambaram, Dong Hu, Pete Gough, John Bertin, Ari Melnick, Gary Kohanbash, Riyue Bao, Peter Lucas, Linda Mcallister-Lucas

College of Life Sciences Faculty Papers

MALT1 protease is an intracellular signaling molecule that promotes tumor progression via cancer cell-intrinsic and cancer cell-extrinsic mechanisms. MALT1 has been mostly studied in lymphocytes, and little is known about its role in tumor-associated macrophages. We show that MALT1 is expressed in glioblastoma (GBM)-associated macrophages. Mechanistically, GBM tumor cells induce a MALT1-NF-κB signaling axis in macrophages, leading to enhanced macrophage migration and polarization toward an immunosuppressive ('M2-like') phenotype. Inactivation of MALT1 protease promotes transcriptional reprogramming that reduces migration and restores a macrophage anti-tumor 'M1-like' phenotype. Preclinical in vivo analysis shows that MALT1 inhibitor treatment results in immuno-reactivity of GBM-associated macrophages …

Grieving And Attentiveness: Perception As Flourishing In Ocean Vuong And Mary Oliver, Madison Smith

Papers

The paper argues that poets Ocean Vuong and Mary Oliver treat grief as something formative to one's life and character rather than purely destructive; through their suffering, the subject has the opportunity to cultivate a sense of attentiveness that transforms perceptions of the self, others, history, and the natural world.

This project was an output for The Belmont Formation Scholars Cohort for Character Research and Writing, which received generous support funding from The Kern Family Foundation.

I gratefully acknowledge peer review feedback on this project, and I am accountable for writing of this product without generative AI and in alignment …

Mystical Revelation And Knowledge Of God: Reclaiming Spirituality In Theology Through The Mystics, Elizabeth A. Merski

Electronic Theses and Dissertations

Since the scholastic era, the pursuit of God has occurred preeminently through reason, leading to an imbalanced theology of God that persists to the present day in the form of intellect-centered theology. As a resolution, this work proposes that the mobilization of private, mystical revelation as a source of legitimized theological knowledge of God has the potential to close the existent epistemological gap between reason/belief and theology/spirituality, demonstrating the integral unity between authentic knowledge of God and the receiver’s personal acceptance of God in faith. After examining the required methodological components for the discipline of theology and identifying criteria for …

Cross-Reactivity Of 15 Jev Antigen-Directed Rabbit Antisera With Three Clinically Important Jev Serogroup Members: Wnv, Mvev, And Slev, Sang-Im Yun, Young-Min Lee

Animal, Dairy, and Veterinary Science Faculty Publications

Japanese encephalitis virus (JEV), the prototype member of the JEV serogroup within the genus Orthoflavivirus (family Flaviviridae), is closely related to West Nile virus (WNV), Murray Valley encephalitis virus (MVEV), and St. Louis encephalitis virus (SLEV). To characterize antigenic cross-reactivity within this group, we evaluated 15 region-specific rabbit antisera, previously generated against nearly the entire JEV protein-coding region, by immunoblotting whole-cell lysates from BHK-21 cells infected with WNV, MVEV, or SLEV, with JEV included as a reference. Six antisera (α-E^N-term, α-NS2B, α-NS3^N-term, α-NS3^C-term, α-NS5^N-term, and α-NS5^C-term) robustly recognized homologous …

Understanding The Long-Term Patterns Of Change Of A Tidal Marsh In Mission Bay, San Diego, California, Carrie A. Shuster, Theresa Sinicrope Talley Ph.D., Drew Talley Ph.D., Zhi-Yong Yin Ph.D., Kellie Uyeda Ph.D.

Theses

Coastal marshes are among California’s most productive ecosystems and the most impacted, having been extensively modified by dredging, filling, and urban development. This thesis investigates over a century of change for a marsh in Northern Mission Bay, San Diego, California using ecological and spatial analyses.

Chapter 1 provides an overview of the environmental history and current land use of the Northern Mission Bay marsh, tracing changes from pre-contact Indigenous stewardship through colonial and modern urban development. It also introduces a restoration plant palette derived from historical and contemporary species occurrences, ecological functions, and documented cultural uses. By integrating ethnobotanical knowledge …