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2025

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Defiance Through Noise, Tyler Paz Dec 2025

Defiance Through Noise, Tyler Paz

Capstones

Defiance Through Noise analyzes the eviction of Punk HQ from 39 Eldridge Street within the broader history of punk-led, DIY, and squatted spaces in New York City. Using court records, historical context, and firsthand accounts from organizers, former nonprofit workers, and participants, the project examines Punk HQ as both a community space for marginalized youth and a continuation of Lower East Side squatting traditions from the 1970s and 1980s. The reporting situates its closure within intersecting forces of government disinvestment, housing policy, post-pandemic economic pressures, and the nonprofit industrial complex that have contributed to the decline of autonomous cultural spaces. …


Beyond The Model Minority: South Asian New Yorkers Confront Poverty, Mizuki Uchiyama Dec 2025

Beyond The Model Minority: South Asian New Yorkers Confront Poverty, Mizuki Uchiyama

Capstones

This capstone project examines poverty among South Asian immigrants in New York City, challenging the “model minority” myth that portrays Asian Americans as uniformly successful. Through a reported NY1 television news package and accompanying written narrative, the project highlights how language barriers, economic insecurity and limited access to public benefits shape daily life for many immigrant families in Queens.

Reporting from the South Asian Council for Social Services (SACSS) in Flushing, the story connects individual experiences in workforce and sewing programs to broader data showing that Asian New Yorkers experience poverty at rates comparable to Black and Latino residents, with …


Building Another World, Christopher Edwards Dec 2025

Building Another World, Christopher Edwards

Capstones

"Another World" is a mutual aid hub in Crown Heights, Brooklyn. The space was opened in June 2025 and is ran by the Crown Heights Care Collective, a mutual aid network started in 2022. Another World hosts free events surrounding political education and provides basic needs like food and clothing to residents of the area. In just a few months, the group has made inroads in a diverse community altered by gentrification.


From Plaque To Tumour: Follicular Neoplasm Arising In Congenital Nevus Sebaceous, Tasneem Hamed Al Salmani, Suad Al Jahdhami, Nawaf Al Muqaimi, Ayida Al Khalili Dec 2025

From Plaque To Tumour: Follicular Neoplasm Arising In Congenital Nevus Sebaceous, Tasneem Hamed Al Salmani, Suad Al Jahdhami, Nawaf Al Muqaimi, Ayida Al Khalili

Sultan Qaboos University Medical Journal

No abstract provided.


Krasg12d Mutation Promotes Pancreatic Tumorigenesis By Suppressing Sirtuin Three Via The Guanine Nucleotide Exchange Factor Rcc1, Taoyi Mai, Mengwen Wang, Ya Qiu, Wenhua Lu, Hongyu Wu, Shuna Chen, Paul J Chiao, Peng Huang Dec 2025

Krasg12d Mutation Promotes Pancreatic Tumorigenesis By Suppressing Sirtuin Three Via The Guanine Nucleotide Exchange Factor Rcc1, Taoyi Mai, Mengwen Wang, Ya Qiu, Wenhua Lu, Hongyu Wu, Shuna Chen, Paul J Chiao, Peng Huang

Faculty, Staff and Student Publications

KRASG12D mutation is a prevalent gain-of-function mutation that drives pancreatic cancer tumorigenesis, but the underlying mechanisms that promote KRAS-induced cell proliferation and tumor formation remain elusive. To uncover the molecular pathways that facilitate KRASG12D-driven malignant transformation, we measured the transcriptomic alterations at various time points after induction of KRASG12D expression in human pancreatic normal epithelial cells. KEGG pathway enrichment of the differentially expressed genes (DEGs) showed that the major DEGs were located in pathways that regulate nicotinate/nicotinamide metabolism, TNF signaling, and microRNAs associated with cancer. Among these molecular alterations, the NAD-dependent deacetylase gene SIRT3 was significantly down-regulated by KRASG12D. Conversely, …


Methodology For The Pediatric Dose Optimization For Seizures In Emergency Medical Services (Pedidose) Study, Manish I Shah, Kathleen M Adelgais, James M Chamberlain, Henry E Wang, Lindsey A Morgan, James J Riviello, Rana R Said, Joseph E Sullivan, Kimia F Ghaffari, Kathryn M Kothari, Mohsen Saidinejad, Robert A Lowe, Raymond L Fowler, Catherine R Counts, Claudia R Morris, Jonathan R Studnek, Nancy K Glober, Caleb E Ward, Brian M Clemency, Nicholas Patrick, Rachel D Munn, Graham M Brant-Zawadzki, Christian Martin-Gill, Daniel K Nishijima, Kevin Li, Neomi Sepulveda, John M Vanburen Dec 2025

Methodology For The Pediatric Dose Optimization For Seizures In Emergency Medical Services (Pedidose) Study, Manish I Shah, Kathleen M Adelgais, James M Chamberlain, Henry E Wang, Lindsey A Morgan, James J Riviello, Rana R Said, Joseph E Sullivan, Kimia F Ghaffari, Kathryn M Kothari, Mohsen Saidinejad, Robert A Lowe, Raymond L Fowler, Catherine R Counts, Claudia R Morris, Jonathan R Studnek, Nancy K Glober, Caleb E Ward, Brian M Clemency, Nicholas Patrick, Rachel D Munn, Graham M Brant-Zawadzki, Christian Martin-Gill, Daniel K Nishijima, Kevin Li, Neomi Sepulveda, John M Vanburen

Faculty, Staff and Student Publications

Background: Seizures are one of the most common reasons for emergency medical services (EMS) activation for children, and current EMS practice results in underdosing and delayed delivery of anti-seizure medication. A prehospital evidence-based guideline recommends using intranasal or intramuscular midazolam as first-line treatment for pediatric seizures. Despite attempts to implement these guidelines, one-third of children having a paramedic-witnessed seizure have ongoing seizures on emergency department (ED) arrival; this may be due to inadequate or delayed midazolam dosing. Replacing the error-prone, sequential calculations with age-based midazolam dosing may be simpler, faster, and more effective without compromising safety. The objective of this …


Diplomacy Derailed: Discrimination’S Detour On Route 40, Gage A. Kivlen Dec 2025

Diplomacy Derailed: Discrimination’S Detour On Route 40, Gage A. Kivlen

Masters Theses, 2020-current

The 1961 Route 40 campaign in Maryland became a critical battleground where three competing approaches to addressing racial segregation revealed deep contradictions in Cold War America. Route 40, a major highway between Washington D.C. and New York, became an international embarrassment when African diplomats from newly independent nations were repeatedly refused service at restaurants and hotels. This crisis prompted responses from three distinct actors: the Congress of Racial Equality (CORE), which employed grassroots organizing and direct action; the State Department's Special Protocol Service Section (SPSS), which pursued top-down diplomatic solutions; and the Federal Bureau of Investigation (FBI), which conducted extensive …


Pen And Punishment: Revenge And Role Reversal In Edith Wharton’S World. A Rewriting Of Gender Roles And The Subversion Of Patriarchy., Shelly Ann Justin Dec 2025

Pen And Punishment: Revenge And Role Reversal In Edith Wharton’S World. A Rewriting Of Gender Roles And The Subversion Of Patriarchy., Shelly Ann Justin

Arts & Sciences Graduate Student Theses and Dissertations

ABSTRACT OF THE DISSERTATION Pen and Punishment: Revenge and Role Reversal in Edith Wharton’s World. A Rewriting of Gender Roles and the Subversion of Patriarchy. by Shelly Ann Justin An unlikely feminist writer sometimes becomes one of the greatest advocates for the feminine movement, and that is exactly what American novelist, Edith Wharton (1862-1937) has done for over 120 years through her essays, short stories, and more specifically, her novels. She is best known for her vivid novels that explore the complexities of American society, especially the upper class which examines the constraints and social expectations of New York’s upper …


Catherine Shipman Burgess Dec 2025

Catherine Shipman Burgess

African American Funeral Programs

No abstract provided.


Lycopene, Race And Periodontitis: Disparities In Older Adults, Katherine Kwong, You Lu, Zhuo Huan Li, Susu Luo, Zhaoyu Huang, Zhong Chen, Na Zhao, Tung Sung Tseng Dec 2025

Lycopene, Race And Periodontitis: Disparities In Older Adults, Katherine Kwong, You Lu, Zhuo Huan Li, Susu Luo, Zhaoyu Huang, Zhong Chen, Na Zhao, Tung Sung Tseng

School of Public Health Faculty Publications

Background Periodontitis is a severe gum disease that can be an indicator of other health conditions such as cardiovascular disease and diabetes. Lycopene has been suggested as an adjunct therapy for periodontitis. This study aims to investigate the association between insufficient lycopene intake and the risk of Periodontitis among non-Hispanic White (NHW) and non-Hispanic Black (NHB) older adults. Methods The study included 1,227 adults aged 65–79 years from the National Health and Nutritional Examination Survey (2009–2014). Total lycopene intake from daily diet was studied with age, race, marital status, smoking status, BMI, diabetes, sex, and education as independent variables in …


Empowering Wireless Mesh Uav Networks Through Software-Defined Networking, Hieu Quang Dec 2025

Empowering Wireless Mesh Uav Networks Through Software-Defined Networking, Hieu Quang

Electrical and Computer Engineering ETDs

Unmanned Aerial Vehicles (UAVs) have been widely deployed in applications such as environmental monitoring, disaster response, and surveillance. Effective coordination between UAVs depends on low-latency inter-UAV communication to exchange state information, decisions, and other critical data. UAV networks are inherently dynamic which necessitates a framework capable of handling scenarios such as traffic re-routing, and resilience to communication failures. To address the challenges of managing dynamic UAV networks, this thesis proposes a dual network approach composed of three main components. First, the Better Approach to Mobile Ad-hoc Networking (BATMAN) protocol is used to enable communication among UAVs. Second, the OpenFlow protocol …


“Bridging The Gap To Midwave Infrared Event-Based Sensors: Design, Sensitivity, And Radiation-Hardness Characterization Of A Single-Pixel Iii-V Event-Based Infrared Sensor For Space Applications, Zinah M. Alsaad Dec 2025

“Bridging The Gap To Midwave Infrared Event-Based Sensors: Design, Sensitivity, And Radiation-Hardness Characterization Of A Single-Pixel Iii-V Event-Based Infrared Sensor For Space Applications, Zinah M. Alsaad

Electrical and Computer Engineering ETDs

Event-based sensing presents a revolutionary paradigm shift for next-generation space surveillance systems, where power consumption is an ever-worsening constraint as temporal resolution demands increase. In addition to reduced power consumption, low latency, and wide dynamic range, the event-based sensor fundamentally only produces data when there is a change in illumination from which events are generated; no data is produced if the scene remains static. With their event-based datastream being inherently focused on the dynamic information of the scene, they are particularly well-suited to machine vision and autonomous sensing applications. While these sensors have many compelling advantages, there are presently no …


Emulation Of Orbital Dynamics And Control Of Fully Actuated Seven-Axis Prismatic Joint Systems, Bennett Russell Dec 2025

Emulation Of Orbital Dynamics And Control Of Fully Actuated Seven-Axis Prismatic Joint Systems, Bennett Russell

Electrical and Computer Engineering ETDs

This thesis details the system modeling, design, control, simulation, construction, and testing of a fully-actuated seven axis prismatic joint system created for the primary purpose of emulating on-orbit maintenance tasks. Additionally, it seeks to further research of space-based control schemas and investigate stiction as a case study with a mountable hybrid hinge system that emulates stiction. Controllers are evaluated under common limits and metrics, including time to escape, overshoot, mechanical work, and limit-exceedance counts. Comparisons span a PID baseline, deterministic MPC/MPPI, and a probabilistic POMDP policy. Results verify the emulator and hybrid hinge meet the intended design criteria and show …


A Bump Hunting Approach To Finding Interpretable Data Pockets, Tushar Ojha Dec 2025

A Bump Hunting Approach To Finding Interpretable Data Pockets, Tushar Ojha

Electrical and Computer Engineering ETDs

This dissertation approaches the problem of extracting simple interpretations from local regions of data. This is sometimes called bump hunting because the local regions of interest have a high concentration of a particular output value. This work develops a bump hunting method for discrete-valued tabular data where each bump is modeled by a rectangular region of the input data space so its rule-based description admits a simple logical interpretation that can inform decisions. This method is designed for labeled data where each input feature has a distinct meaning that may or may not be related to the output, and the …


Paper Straws At Usd, Rodrigo J. Mor Gimeno Dec 2025

Paper Straws At Usd, Rodrigo J. Mor Gimeno

Sustainable Supply Chain Management

This learning journal reflects my experience throughout the semester learning about sustainability, climate change, and supply chains. Through class discussions, documentaries, and assignments, I explored topics such as carbon footprint, circular economy, ethics, and life cycle analysis. The paper on plastic straws and the group life cycle project helped me understand how everyday products have environmental, social, and economic impacts, and how consumer choices and global systems are strongly connected.


Knowledge Production As Identity Expression: A Third-Space Perspective On Sustainable Careers, Alicja Syska Dec 2025

Knowledge Production As Identity Expression: A Third-Space Perspective On Sustainable Careers, Alicja Syska

School of Law, Humanities and Social Sciences

This conceptual paper advances our understanding of sustainable careers by focusing on the knowledge creation activities of third-space practitioners in higher education. Specifically, we apply and extend the Process Model of Sustainable Careers to examine how different forms of knowledge production in three different institutional and national contexts – writing for publication, practice-based expertise, and curriculum development – contribute to career sustainability at the intersection of academic and professional/administrative roles and domains. The critical element of this extension is ‘identity expression’ in the form of knowledge production, which acts as an integrating mechanism that flows through and connects the original …


Protein-Nucleic Acid Language Model-Assisted Design Of Precise And Compact Adenine Base Editor, Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang Dec 2025

Protein-Nucleic Acid Language Model-Assisted Design Of Precise And Compact Adenine Base Editor, Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang

Faculty, Staff and Students Publications

Adenine base editors (ABEs) are powerful tools for gene therapy. However, efficient version of ABEs (e.g. ABE8e) always induce excessive bystander and off-target editing events and are large in size, hindering their potential in clinical disease treatment. Here, we develop a pre-trained Protein-Nucleic Acid Constrained Language Model to design ABE8e with high activity, reduced editing window and decreased size. By further engineering, the smallest ABE8e- PNLM-pcABE- with a 27% size reduction, exhibits high activity, precise 3-nt editing window, and reduced off-target events near background level in HEK293T cells. Compared to ABE8e, PNLM-pcABE has up to 133.5-fold precision improvement in pathogenic …


Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana Dec 2025

Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana

2020-Current year OA Pubs

Intermittent fasting (IF) has gained attention as a potential intervention for cardiometabolic health, though its long-term effects remain unclear. In this randomized clinical trial, we assessed the impact of 6 months of IF on body composition, cardiovascular risk factors, and related molecular pathways in middle-aged (30-65 years) men and women with overweight (BMI 24.8-35 kg/m²). In this trial, 41 participants were randomized to either an intermittent fasting (IF) intervention or to maintain their habitual diet. The primary outcome (circulating CRP concentration) was previously reported; here, we present exploratory analyses focusing on metabolomic and transcriptomic responses. IF led to an 8% …


A Multivalent Capsule Vaccine Protects Against Klebsiella Pneumoniae Bloodstream Infections In Healthy And Immunocompromised Mice, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Isra Darwech, Aline M Matsuguma, Evgeny Vinogradov, Nichollas E Scott, Christian M Harding, David A Rosen Dec 2025

A Multivalent Capsule Vaccine Protects Against Klebsiella Pneumoniae Bloodstream Infections In Healthy And Immunocompromised Mice, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Isra Darwech, Aline M Matsuguma, Evgeny Vinogradov, Nichollas E Scott, Christian M Harding, David A Rosen

2020-Current year OA Pubs

Klebsiella pneumoniae is a leading cause of nosocomial infections, bacteremia, and worldwide mortality. Further, a drastic rise in antibiotic-resistant isolates poses an urgent threat to humanity. Unfortunately, despite its clinical importance, a licensed K. pneumoniae vaccine is not yet available. Here, we report on the production and characterization of the broadest K. pneumoniae capsule bioconjugate vaccine to date. We tested this vaccine for its immunogenicity, functionality, efficacy, and antibody durability against a variety of K. pneumoniae isolates in a murine bacteremia model. We also established an immunocompromised murine model of bacteremia to better recapitulate human infection and tested our vaccine's …


Revisiting The 2015 Mds Diagnostic Criteria For Parkinson Disease: Insights From Autopsy-Confirmed Cases, Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder Dec 2025

Revisiting The 2015 Mds Diagnostic Criteria For Parkinson Disease: Insights From Autopsy-Confirmed Cases, Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder

2020-Current year OA Pubs

The 2015 International Parkinson and Movement Disorder Society (MDS) Diagnostic criteria for Parkinson Disease are based on expert consensus opinion and defines core motor features, 'Absolute Exclusion Criteria' and a balance of 'Supportive Criteria' and 'Red Flags'. To assess validity of each criterion in pathologically-confirmed cases, a scoping literature review between 1988-2024 using search terms for clinicopathological PD and atypical parkinsonian disorders identified 28 articles. Supportive criteria were higher in PD, with excellent levodopa response and rest tremor most useful. Absolute exclusion criteria and red flags were present more often in atypical parkinsonian disorders. However, supranuclear gaze palsy, rapid progression …


Book Review: Academic Coaching: Coaching College Students For Success, Corinne Bishop Dec 2025

Book Review: Academic Coaching: Coaching College Students For Success, Corinne Bishop

Journal of Graduate Librarianship

Book review: Howlett, M. A., & Rademacher, K. (2023). Academic coaching: Coaching college students for success. Routledge. 196 pp. ISBN: 9781032272214 (paperback), 9781032265711 (hardcover), 9781003291879 (ebook).


Pembuktian Sederhana Dalam Proses Kepailitan Terhadap Perusahaan Pengembang Pasca Surat Edaran Mahkamah Agung Nomor 3 Tahun 2023, Maya Iswandi Dec 2025

Pembuktian Sederhana Dalam Proses Kepailitan Terhadap Perusahaan Pengembang Pasca Surat Edaran Mahkamah Agung Nomor 3 Tahun 2023, Maya Iswandi

Jurnal Hukum & Pembangunan

Abstract

After the issuance of Sema No. 3/2023, there were various pros and cons to its implementation. This is because the sema has limited and in quotes has protected development companies from bankruptcy proceedings. Sema No. 3/2023 provides immunity to development companies from bankruptcy because they are deemed not to meet the simple proof that must be met in the bankruptcy process. This provision seems to deny the judicial system that should determine the evidence in a case. This certainly causes degradation of legal certainty and consumer protection. Therefore, this research will discuss simple proof in development companies after the …


Prevention Of Suicide As Perceived By Educated Adults In Ondo Metropolis, Ondo State, Nigeria, Margaret Kehinde Soetan Dec 2025

Prevention Of Suicide As Perceived By Educated Adults In Ondo Metropolis, Ondo State, Nigeria, Margaret Kehinde Soetan

Buletin Konseling Inovatif

This study investigated prevention of suicide as perceived by educated adults in Ondo metropolis, Ondo State, Nigeria. Descriptive survey research design was adopted for this study. Population of the study consisted of all educated adults in Ondo metropolis, Ondo State. The sample comprised two hundred (200) educated adults randomly selected from the metropolis. Structured questionnaire was used as instrument to collect data for the study. Data collected was analysed using mean, ranking, t-test and analysis of variance (ANOVA). The results revealed the perception of prevention of suicide as giving people hope for a better life after current problems are resolved, …


Needs Analysis: Ar As An Innovative Learning Media Solution For Elementary School Students, Rosfaniarti Rosfaniarti, Makmum Raharjo, Meilinda Meilinda Dec 2025

Needs Analysis: Ar As An Innovative Learning Media Solution For Elementary School Students, Rosfaniarti Rosfaniarti, Makmum Raharjo, Meilinda Meilinda

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims to identify the need for the development of Augmented Reality (AR)-based learning media as an innovative solution in elementary school learning. The needs analysis method was conducted using a mixed methods approach through questionnaires and interviews with 103 students and 5 teachers. The data were analyzed descriptively and quantitatively to obtain a comprehensive picture of instructional needs. The results showed that student needs were in the high category, with a percentage of 80.64%-85.30%. The socio-cultural aspect was the highest need (85.30%), followed by the pedagogical and technical aspects, while the cognitive aspect had the lowest value (80.64%). …


Improvising Across Abilities: Pauline Oliveros And The Adaptive Use Musical Instrument [Book Review], Maria A. Souliotis Dec 2025

Improvising Across Abilities: Pauline Oliveros And The Adaptive Use Musical Instrument [Book Review], Maria A. Souliotis

Disability in LIS (DisLIS)

This book reviews how the AUMI movement has evolved in the years since its inception, with the people involved in it most closely detailing its impact on music education and disability activism. Narratives, case studies, and personal reflections highlight Oliveros’ philosophical and realized contributions to the AUMI movement, which until this book’s publication has received little attention.


Becoming Steve Bright, Robert L. Tsai Dec 2025

Becoming Steve Bright, Robert L. Tsai

Kentucky Law Journal

No abstract provided.


¿Cómo Se Dice, "Liberty And Justice For All Cannot Exist Without Equal Access For All" En Español?, Turner Denise Reynolds Dec 2025

¿Cómo Se Dice, "Liberty And Justice For All Cannot Exist Without Equal Access For All" En Español?, Turner Denise Reynolds

Kentucky Law Journal

No abstract provided.


Like Balance On Ice: Towards A New Approach To The Open And Obvious Doctrine Under Kentucky Law, Hayden T. Crosby Dec 2025

Like Balance On Ice: Towards A New Approach To The Open And Obvious Doctrine Under Kentucky Law, Hayden T. Crosby

Kentucky Law Journal

No abstract provided.


Just A Place Or A Just Place?: Domestic Violence, Urban-Rural Differences, And Access To Justice, Cassie Chambers Armstrong Dec 2025

Just A Place Or A Just Place?: Domestic Violence, Urban-Rural Differences, And Access To Justice, Cassie Chambers Armstrong

Kentucky Law Journal

No abstract provided.


Prosecutorial Discretion And Digital Democracy, Erin Sheley Dec 2025

Prosecutorial Discretion And Digital Democracy, Erin Sheley

Kentucky Law Journal

No abstract provided.