Digital Commons Network^™

Examining Religiosity, Suicidality, And Internalized Homonegativity Among Ethnoracially Diverse Sexual Minority Students, Danica Christy

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sexual minority (SM) individuals are at an elevated risk for suicidality, particularly those who hold multiple marginalized identities, including religious and racial minority statuses. While religiosity is generally protective against psychological distress and suicide for heterosexual individuals, its impact on SM individuals is more complex. It may function as both a risk and a protective factor. The current mixed methods study explored the relationships between religiosity, internalized homonegativity (IH), and suicidality among an ethno-racially diverse sample of college students (n = 246). Quantitative analyses revealed that SM participants (n = 123) reported significantly higher rates of suicidality than their heterosexual …

Enviromental Dna (Edna) Tools For Invasive Mosquitofish (Gambusia Affinis) Surveillance At The Shoshone Pupfish (Cyprinidon Nevadensis Shoshone) Refugium, Yusuf Olamilekan Umar

UNLV Theses, Dissertations, Professional Papers, and Capstones

Spring-fed aquatic ecosystems of the North American Southwest and U.S. Great Basin hosts a plethora of endemic fish species due to the effects of hydrologic fragmentation that resulted from Pleistocene aridification. Threats to endemic fishes worldwide include human intentional or unintentional release of exotic species into their habitats. Early detection of invasive species, while corrective actions are still possible, is critical for management, yet traditional survey methods are often disruptive to sensitive ecosystems, costly, and limited in sensitivity. The recent development of environmental DNA (eDNA) approaches offers powerful alternatives for invasive species monitoring in aquatic systems. In this study, a …

Targeting Kinesin Family Member 20a Sensitizes Stem-Like Triple-Negative Breast Cancer Cells To Standard Chemotherapy, Yayoi Adachi, Weilong Chen, Cheng Zhang, Tao Wang, Nina Gildor, Rachel Shi, Haoyong Fu, Masashi Takeda, Qian Liang, Fangzhou Zhao, Hongyi Liu, Jun Fang, Jin Zhou, Hongwei Yao, Lianxin Hu, Shina Li, Lei Guo, Lin Xu, Ling Xie, Xian Chen, Chengheng Liao, Qing Zhang

Faculty, Staff and Student Publications

Triple-negative breast cancer (TNBC), being both aggressive and highly lethal, poses a major clinical challenge in terms of treatment. Its heterogeneity and lack of hormone receptors or HER2 expression further restrict the availability of targeted therapy. Breast cancer stem cells (BCSCs), known to fuel TNBC malignancy, are now being exploited as a vulnerability for TNBC treatment. Here, we dissected the transcriptome of BCSCs and identified kinesin family member 20A (KIF20A) as a key regulator of BCSC survival and TNBC tumorigenesis. Genetic depletion or pharmacological inhibition of KIF20A impairs BCSC viability and tumor initiation and development in vitro and in vivo. …

Itpr1 Autoantibody-Associated Autoimmunity As A Cause Of Newly Emerging Cognitive Decline Mimicking Alzheimer's Disease: Case Report And Brief Review Of The Literature, Nicolas Kunath, Hermod Arne Bollandsås Ramfjord, Elisabeth Volden Kvisvik, Marton Konyves-Kolonics, Gøril Rolfseng Grøntvedt, Irina I Serysheva, Lars Komorowski, Brigitte Wildemann, Sven Jarius

Faculty, Staff and Student Publications

Background: Since its first description in 2014, anti-inositol 1,4,5-trisphosphate receptor type 1 (ITPR1, also termed IP3R1) autoimmunity has been recognized as causing a clinically heterogeneous spectrum of symptoms. While first described in patients with autoimmune cerebellar ataxia, this facultative paraneoplastic disease has been associated also with peripheral neuropathy, dysautonomia, sleep disorders, neuropsychiatric/psychotic symptoms, and cognitive decline.

Methods: Retrospective case study.

Results: We report the case of a 58-year-old patient who was admitted with acute confusion, rapidly progressive cognitive decline, and hallucinations. A history of mild cognitive impairment over several years and low cerebrospinal fluid (CSF) amyloid beta-42 and elevated CSF …

Protocol For Isolation Of Lipid Droplets And Mitochondria From Acute Myeloid Leukemia Cells For Lipidomic Analysis, Ran Zhao, Liang Zhang, Shuxin Dong, Kazuharu Kamachi, Saurabh Kumar Gupta, Hiroki Akiyama, Jalen Nguyen, G Lavender Hackman, Michael Andreeff, Alessia Lodi, Jo Ishizawa

Faculty, Staff and Student Publications

Lipid droplets (LDs) are dynamic organelles critical for lipid and energy homeostasis. LD dysregulation is implicated in various diseases, including acute myeloid leukemia (AML), which exhibits aberrant lipid metabolism and chemoresistance. Here, we describe an effective protocol for the co-isolation of LDs and mitochondria from lipid-deficient cell types, e.g., AML cells. We detail procedures for the isolation, quality verification, and results from mass spectrometry-based lipidomic analysis. This protocol enables the functional study of organellar lipidomic regulation in AML.

Development Of Broadly Protective Vaccines Against New World Arenaviruses, Brian B. Gowen

Funded Research Records

No abstract provided.

The Double Patenting Puzzle, Michael Risch

Faculty Publications

It’s a simple rule: one patent per invention. This is easy to enforce when patent claims in two patents are identical, but what if the second patent claims something close but not quite the same? For more than 150 years, courts have held that obvious improvements over the prior art cannot be patented. But when inventors seek a small improvement in their own follow-on patents, there may not be any prior art because the law does not typically count inventors’ work against themselves. Inventors can include two similar claims in the same patent without objection, but if they split them …

Holistic Support And Development: Collaboration Between Residence Life And Faculty On Short-Term Education Abroad Programs, Kendra Sherman

Seton Hall University Dissertations and Theses (ETDs)

Short-term education abroad programs are designed to increase students’ intercultural competencies, expose them to new cultures and languages, prepare them for future employability, and further their academic development (Castiello-Gutiérrez & Gozik, 2022; Yao, 2021). While education abroad programs may result in strong benefits for students, they are not without their challenges when it comes to facilitating and managing them. Both the faculty who lead these programs and the students who participate in them face challenges respective to their experiences abroad. Many researchers emphasize collaboration between student affairs and academic affairs to alleviate these challenges, but no one office is identified …

When Prayers Aren’T Enough: The Need For Mission Formation And Professional Development For Lay Faculty At Catholic Colleges And Universities, Lucy A. Pesce

Seton Hall University Dissertations and Theses (ETDs)

Current literature suggests that administration and faculty must make a more intentional effort within Catholic higher education to articulate the mission of these religiously-affiliated institutions in response to two current issues: dwindling numbers of clergy and vowed religious faculty and administrators, and fewer students nationwide who self-identify with any form of organized religion. However, few studies have examined the experience of lay faculty at Catholic institutions who are entrusted with advancing the mission, regardless of their religious affiliation, and their professional development needs.

Using the Association of Catholic Colleges and Universities’ Catholic Identity and Mission Assessment (CIMA) as a framework …

Investigation Of Mono-Allelic Rack1 Deletion Effects On Cell Growth And Pkc Mrna Expression, Ashen Quiambao

Seton Hall University Dissertations and Theses (ETDs)

The µ-opioid receptor is a primary target of clinically used opioids, and RACK1 regulates its transcription by physically interacting with MOR transcription regulator PCBP1 in the cytosol to prevent its nucleus translocation. Two mono-allelic RACK1 knockout cell lines named RACKA and RACKB were generated by the CRISPR-Cas9 technique using WT NMB neuroblastoma cells. As RACK1 also contains a PKC-binding domain, this study aims to evaluate the impacts of mono-allelic deletion on cell growth rates and PKC isoform expression. Although a slight decreased tendency of growth rate in RACKA and RACKB cells was observed when compared to that of WT NMB …

Examining Aba Classroom Paraprofessional Training Methods In New Jersey, Melina Campos

Seton Hall University Dissertations and Theses (ETDs)

In recent years, paraprofessionals have become an integral part of educational teams, particularly in classrooms supporting students with disabilities (Giangreco et al., 2010). Their role has been crucial in ensuring that students received necessary academic and social support. This study evaluated the training provided to paraprofessionals in New Jersey, specifically those working in applied behavior analysis (ABA) classrooms. By surveying paraprofessionals on training that they receive and assessing how training influenced their self-perceived knowledge and skills, the study offered insight into how well-prepared these educators felt to support students with disabilities. A total of 57 participants completed the survey. When …

The Implementation Of Tact And Bidirectional Intraverbal Training In Teaching A Foreign Language: A Systematic Replication, Karen Parra Caballero

Seton Hall University Dissertations and Theses (ETDs)

The current study replicates and extends Yamaguchi and Matsuda (2024) to evaluate the effects of foreign tact and bidirectional intraverbal training on teaching foreign-language vocabulary to adults. An adapted alternating-treatments design was used to evaluate the effects of learning vocabulary of a foreign language through tact teaching (tacting a picture in French), foreign-native intraverbal teaching (vocalizing a French word in the presence of the Spanish word), and native-foreign intraverbal teaching (vocalizing a French word in the presence of the Spanish word). Each teaching condition had an assigned stimulus set for teaching, and an additional stimulus set was included as a …

The Impact Of Youth Sports Participation On Academic Performance And Sense Of Belongingness In Middle School Students, Kevin Stahl

Seton Hall University Dissertations and Theses (ETDs)

This quantitative study explored the relationship between youth sports participation, academic achievement, and sense of belonging among middle school students. Using data from the Middle Grades Longitudinal Study of 2017–2018 (MGLS; National Center for Education Statistics [NCES], 2018), the research examined whether involvement in youth sports predicts outcomes in mathematics, reading, and students’ perceived connection to their school environment.

The findings challenged the extent to which Astin’s (1984) theory of student involvement generalizes to early adolescent populations. Although the theory proposes participation in structured activities supports both academic and social outcomes, results indicated stronger and more consistent associations between sports …

Gender Equality Discourse: A Japanese Context, Gabriel Eweje, Hitomi Toyosaki, Kazunori Kobayashi, Sitong Michelle Chen, Masahiro Hosoda

Research outputs 2022 to 2026

Purpose – This review paper aims to critically examine the discourse on gender equality in Japan, focusing on its socio-cultural, economic and political dimensions. By synthesising existing literature, it provides a comprehensive understanding of the complexities and barriers that influence the gender equality debate in Japan, while identifying gaps and opportunities for future research and specifying where practice can be recoupled to policy. Design/methodology/approach – An integrative literature review was conducted across four key institutional domains – markets, government/public sector, families and education – analysed at the macro, meso and micro levels. The synthesis is integrative rather than exhaustive, prioritising …

How Climate For Green Initiatives Drives Eco-Innovative And Citizenship Behaviours: The Role Of Green Engagement And Green Values, Aaron Makafui Ametorwo, Michael Kyei-Frimpong, Abdul Razak Suleman

Research outputs 2022 to 2026

Purpose This study proposes and tests the nexus between climate for green initiatives, green innovative behaviour, organisational citizenship behaviour for the environment, green work engagement, and individual green values. Design/methodology/approach The study adopted the explanatory research design, where data were gathered from 374 star-rated frontline employees at two different waves within a one-month interval. The data retrieved from the respondents were analysed using descriptive and inferential (partial least squares structural equation modelling) statistics. Findings The study revealed that a climate for green initiatives positively and significantly relates to green innovative behaviour and organisational citizenship behaviour for the environment. Also, the …

Elucidating The Role Of Pbaf Chromatin Remodeling Subunit Arid2 In B Cell Development, Rachel Paolini

Arts & Sciences Graduate Student Theses and Dissertations

B cells are key components of the adaptive immune system that mediate humoral immunity through the production of antigen-specific antibodies. The generation of functional B cells involves multiple stages of differentiation across distinct anatomical niches, requiring precise regulation of microenvironmental signals and intrinsic transcriptional networks. SWI/SNF chromatin remodeling complexes have emerged as key regulators of B cell lineage commitment by modulating the accessibility of transcriptional programs required for differentiation and maturation. However, the specific roles of individual SWI/SNF subunits and distinct complexes within early B cell differentiation remain poorly understood. In this thesis, I investigated the function of Arid2, an …

Opening Brief For Plaintiff-Appellant Emery Barron, Steven Mitchell, Carolyn Sacco, Shaina Sikka, Madeline H. Meth

Faculty Scholarship

By the time Emery Barron sued Pennsylvania Department of Corrections officials in 2021, they had kept him caged for almost six years in solitary confinement without providing a pathway for him to reenter general population. Department of Correction policy calls for officials to review the ongoing need for solitary confinement after an initial ninety-day stint in disciplinary confinement. However, procedural carve outs allow officials to leave people like Barron in solitary indefinitely without an opportunity to be heard by a decisionmaker and without requiring officials to assert any legitimate penological interest behind the confinement.

Under this scheme, which violated both …

Oxytocin Varies Across The Life Course In A Sex-Specific Way In A Human Subsistence Population, Abigail E. Colby, Dominik C. Jud, Valerie Baettig, Jordan S. Martin, Camila Scaff, Michael D. Gurven, Benjamin C. Trumble, Bret A. Beheim, Paul L. Hooper, Daniel K. Cummings, Hillard Kaplan, Jonathan Stieglitz, Arnulfo Cary Ista, Adrian V. Jaeggi

ESI Publications

Oxytocin, a hormone linked to reproduction and health, may mediate life-history trade-offs across the human life course. Yet, how oxytocin naturally varies with age remains poorly understood. Here, working with the Tsimane, forager-horticulturalists of lowland Bolivia, we collected the largest sample of oxytocin measurements to date (n = 1,242 samples, n = 405 individuals, age = 2 to 84 y, 51% female), and i) examined how oxytocin varies throughout the life course in females and males, and ii) investigated potential drivers of age- and sex-specific variation. Our sample provides rare insight into the relationship between oxytocin and age in a …

Beyond Barriers: Improving Employment Outcomes For Young Adults On The Autism Spectrum, Kendra L. Cope

UNLV Theses, Dissertations, Professional Papers, and Capstones

Young adults with autism spectrum disorder (ASD) continue to face persistent barriers to employment, often stemming from challenges in communication, adaptability, and multitasking. Virtual reality (VR) has emerged as a promising tool to strengthen these employment skills through immersive, low-stress practice. This study evaluated a VR-based intervention using Floreo VR modules, guided practice, and performance feedback to enhance job readiness among high school students with ASD. A multiple-probe design across three skill domains: multitasking, handling interruptions and changes, and workplace communication to examine skill acquisition and maintenance with three students with ASD aged 16–18. Data from task-analysis checklists, interobserver agreement …

Intervention Outcomes Of A Family-Based Intervention: A Case Review Of An Asian American Adolescent At Clinical High Risk For Psychosis, Monica Elizabeth Done

UNLV Theses, Dissertations, Professional Papers, and Capstones

Schizophrenia is a lifelong and debilitating condition that occurs in approximately 1% of individuals globally and includes positive, negative, disorganized, and other symptoms that interfere with functioning. The onset typically happens in adolescence, and recently, there has been an emphasis on finding individuals who are at high clinical risk for developing psychosis (CHR-P). Additionally, there has been a focus on creating intervention programs that may treat symptoms in the early phases of illness and decrease the likelihood of developing a schizophrenia spectrum and other psychotic disorders (SSD). Furthermore, there is limited research on the potential impacts of cultural identity on …

Towards Spatial Inversion Of Aerial Gamma-Ray Survey Data For Measurement Of Naturally Occurring Radioactivity, Daniel A. Haber

UNLV Theses, Dissertations, Professional Papers, and Capstones

Aerial gamma-ray surveying (AGRS) is used in geologic and environmental contexts to provide data on the surface spatial distribution of naturally occurring radioactive material (NORM) or other gamma-ray-emitting isotopes. The standard data reduction workflow for AGRS data involves a process whereby pointwise gamma-ray spectral data are denoised, corrected for numerous sources of background radiation and aircraft height, and are finally converted to physical values by empirical conversion factors. The reduced pointwise data are then typically spatially interpolated to form a continuous surface map.

This dissertation introduces and explores a novel spatial inversion method for reduced AGRS data that considers aircraft …

A Phenomenological Study Of The Experiences Of Adolescents With Emotional Behavioral Disorders In High School, Melissa Lawson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Adolescents with emotional and behavioral disorders (EBD) face significant challenges in forming and maintaining peer relationships, yet their voices and lived experiences remain largely absent from the research literature. This phenomenological study explored how high school students with EBD perceive the impact of peer relationships on their academic, social, and emotional experiences at school. Using Moustakas's (1994) modification of the StevickColaizzi-Keen method, the researcher conducted in-depth semi-structured interviews with seven high school students (ages 15-18) who had received special education services under the EBD eligibility category for 5 to 10 years in a large, urban southwestern school district.

Five universal …

Reconstructing Central American Hydroclimate Changes Across Time From Isotopic Signatures In Modern And Paleo-Rainfall Records, Giuseppe Lucia

UNLV Theses, Dissertations, Professional Papers, and Capstones

Tropical monsoon rainfall is a key component of Earth’s climate system and supports the livelihood and economy of billions of people. Yet, projections of future monsoons remain highly uncertain, particularly in regions with distinct physiography and complex land-ocean-atmosphere interactions like Central America, where long and continuous high-resolution paleoclimate data to test climate model simulations are still limited. This series of studies aims to reconstruct monsoon dynamics and underlying forcing controls in Central America on multiple timescales by the analysis and integration of stable isotope data in modern and paleo-rainfall records from Guatemala.

In Chapter 2, I present a daily-resolution, two-year-long …

Ankimedbench: Evaluating Hierarchical Medical Knowledge In Language Model Embeddings, Neel Patel

UNLV Theses, Dissertations, Professional Papers, and Capstones

Despite achieving over 90% accuracy on medical benchmarks, recent studies show physicians cannot effectively leverage language models to improve clinical reasoning. Current benchmarks test isolated factual recall, but clinical practice requires hierarchical navigation through diagnostic categories—starting broad and narrowing systematically from chest pain to cardiovascular pathology to myocardial infarction to specific STEMI types. Existing evaluations cannot measure whether models preserve this taxonomic structure essential for clinical reasoning.

We introduce AnkiMedBench, built from 16,512 medical flashcards used by students preparing for licensing exams. Cards are organized across six hierarchy levels spanning 16 broad medical specialties to 672 specific diseases and conditions. …

A Competency Based Pressure Injury Management Program, Madina Qadir

UNLV Theses, Dissertations, Professional Papers, and Capstones

This project aims to implement a simulation-based wound management program to address critical gaps in nurses’ competencies for managing pressure injuries (PIs). The initiative seeks to enhance nurses’ knowledge, clinical skills, and confidence in wound assessment and advanced therapies, fostering evidence-based practice and consistent care delivery. Effective PI management is vital for improving patient outcomes, reducing healing times, and minimizing complications. Yet, nursing education and competency gaps often lead to inconsistent care and increased healthcare costs. A structured competency-based pressure injury management (CB PIM) program integrates evidence-based didactic lectures and interactive simulation-based skills stations to cover essential topics, including wound …

Perceptions And Behaviors Of Female Title I Principals And Faculty Trust In The Post-Covid-19 Educational Environment, Jessica A. Robbins

UNLV Theses, Dissertations, Professional Papers, and Capstones

Faculty trust in principals is essential to a healthy school culture, yet it remains one of the most fragile and complex aspects of leadership, particularly in Title I schools (Tschannen-Moran, 2007, 2014; Tschannen-Moran et al., 2015). While trust has been widely studied, fewer investigations have focused on the specific behaviors female principals use to build trust in the post-COVID era (Berkovich, 2018; Bukko et al., 2021; Handford & Leithwood, 2013; Jeanquart-Barone, 2013; Zajda et al., 2023; Zheng et al., 2021). Research suggests that women in leadership must be deliberate in fostering trust, yet their behaviors are often judged more harshly …

“I Can Gossip With Anybody, I Can’T Chisme With Everybody”: Chisme, Gossip, And Identity In Latina-Americans, Alexa B. Romero

UNLV Theses, Dissertations, Professional Papers, and Capstones

As individuals adjust to their belonging to two distinct cultures, there are various ways of adapting to their navigation of the two cultures (Berry, 1980). The way(s) an individual chooses to adjust to their two cultures can have varying effects on identity. When directly translated, chisme (Spanish) means gossip. Although the two include overlap in function and uses, chisme offers unique purposes for the Latinx community and further, Latina-Americans (González Ybarra & Player 2024; Gutierrez, 2017; Uribe, 2025). By using the communication theory of identity (Hecht, 1993) the purpose of this thesis was to investigate the role of chisme and …

Understanding The Musical Theatre Female Mixed Belt Through The Lens Of The Operatic Tenor: A Comparative Study, Courtney Schwalbe

UNLV Theses, Dissertations, Professional Papers, and Capstones

Since its emergence in the early 20th century, the female belt voice has become central to musical theatre, yet it still receives less systematic attention than classical singing in both scholarship and collegiate pedagogy. This document frames the contemporary female belt, especially the high or mixed belt, in dialogue with the Western operatic tenor to demystify belt production for teachers trained in classical vocal pedagogy. Drawing on historical context, voice science, and applied pedagogy, the study compares defining characteristics, vocal challenges, registration, and resonance strategies across the two traditions. Both voices extend chest-dominant qualities above the primary register transition and …

Las Voices: The Impact On Black Young Males In A Critical Mentorship Program In The Las Vegas Valley, Sean C. Tory

UNLV Theses, Dissertations, Professional Papers, and Capstones

In America, Black young males face an enormous amount of pressure regarding their social and racial identity. They battle with racial macro/microaggressions, stereotypes, racism, and socialization from various industries and systems. The community organization, King of Jewels, has been able to adopt effective strategies to help Black young males navigate these issues through critical mentorship. This paper will first demonstrate the importance of critical mentorship, Black Racial Identity Development, and will then outline the steps necessary to fill the gaps found in mentorship and Black Racial Identity Development literature. This qualitative study investigates the use of critical mentorship (CM) and …

Trauma Beyond Time: Temporal Constructs In Holocaust Testimonies, Sarah Seiselmyer-Snyder

Purdue University Press Books

Trauma Beyond Time: Temporal Constructs in Holocaust Testimonies challenges our understanding of what it means to be a Holocaust survivor, arguing that the term “post-Holocaust” fundamentally misrepresents survivors’ experiences. Through careful analysis of Holocaust literature and testimony, this book reveals how trauma persists across generations, defying conventional historical timelines. For those who perished, there can be no “after” to the Holocaust—their stories were violently ended. Yet for survivors, the Holocaust didn’t simply conclude in 1945. Their experiences demonstrate how trauma continues to shape lives decades later, making “post-Holocaust” a misleading concept that fails to capture their ongoing reality. Using the …