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Articles 158311 - 158340 of 158362
Full-Text Articles in Entire DC Network
A Unified, Data-Informed Model For Shoreline Evolution Due To Longshore And Cross-Shore Processes, Mark Davidson, Emily Hunt, Nieves Valiente
A Unified, Data-Informed Model For Shoreline Evolution Due To Longshore And Cross-Shore Processes, Mark Davidson, Emily Hunt, Nieves Valiente
School of Biological and Marine Sciences
Due partially to a changing global climate, there is an increasing need to develop a modelling approach capable of providing warnings of coastal evolution, including erosion at storm, interannual and decadal timescales and in complex coastal settings. This research presents a reduced complexity model with a common approach to predicting shoreline change due to cross-shore and longshore processes. The model architecture is designed to be flexible and data-informed, incorporating an Extended Kalman (eKF) for the assimilation of field measurements of shoreline change. Depending on the values of the optimised model free parameters resulting from the eKF assimilation, the longshore and …
From Hospital Discharge To Long-Term Care: Unmet Rehabilitation Needs In Cauda Equina Syndrome Patients From A National Uk Cohort, Uces Collaborators, British Neurosurgical Trainee Research Collaborative, Holly Roy, Krithika Anil, Jack Read, Marcus J. Drake, Ingrid Hoeritzauer, Julie Woodfield
From Hospital Discharge To Long-Term Care: Unmet Rehabilitation Needs In Cauda Equina Syndrome Patients From A National Uk Cohort, Uces Collaborators, British Neurosurgical Trainee Research Collaborative, Holly Roy, Krithika Anil, Jack Read, Marcus J. Drake, Ingrid Hoeritzauer, Julie Woodfield
Peninsula Medical School
Objectives: Although long term disability may be a consequence of cauda equina syndrome (CES), the evidence base for the effect of rehabilitation or different rehabilitation strategies is lacking. Our aim was to understand long term neurological deficits (understood as rehabilitation needs) and current rehabilitation provision for patients with CES. Methods: We retrospectively analysed data from a large UK wide cohort of CES patients presenting between 1st June 2018 and 31st May 2019. Rehabilitation referrals and attendance were described, and symptoms at discharge and one year were identified as potential targets for rehabilitation. Results: Physiotherapy was the most common inpatient rehabilitation …
Surf Stewardship And Coastal Change: A Combined Report For The North Devon Unesco Biosphere Reserve And The North Devon World Surfing Reserve, Kizzy Beaumont
Surf Stewardship And Coastal Change: A Combined Report For The North Devon Unesco Biosphere Reserve And The North Devon World Surfing Reserve, Kizzy Beaumont
School of Biological and Marine Sciences
Executive summaryNorth Devon’s coastline sits within a layered governance setting, including statutory marine plans, inshore fisheries management, coastal and shoreline planning, protected areas, and seasonal bathing water monitoring, led by national regulators and local authorities. Within this wider context, this study focuses on how two non-statutory designations, the North Devon UNESCO Biosphere Reserve and the North Devon World Surfing Reserve (WSR), canwork together. The work forms part of a PhD on Transformative Ocean Governance and was motivated by the North Devon WSR’s designation and the opportunity to understand how the two designations might complement each other in practice. We convened …
Surfing Towards Shared Futures - Comparative Insights From Australia's World Surfing Reserves: Part Of The Series: Transformative Ocean Governance In Australia’S World Surfing Reserves - A Community-Centred Perspective, Kizzy Beaumont
School of Biological and Marine Sciences
Executive summaryThis comparative report brings together insights from the Noosa, Gold Coast, and Manly-Freshwater World Surfing Reserves (WSRs), showing how locally led stewardship delivers cultural, environmental, and economic value for coastal communities. Using a Transformative Ocean Governance lens, the analysis synthesises participant perspectives from focus groups and interviews alongside a desk-based review of official materials. Across the three sites there is clear commitment to surf culture, environmental care, and participation, with practical innovations already visible in education, etiquette, and community engagement.The sites follow different but complementary governance paths. Noosa demonstrates how independent stewardship can sit alongside council activity and deliver …
Climate Adaptation For A Natural Atoll Island In The Maldives - Predicting The Long-Term Morphological Response Of Coral Islands To Sea Level Rise And The Effect Of Hazard Mitigation Strategies, F. E. Roelvink, G. Masselink, C. Stokes, R. T. Mccall
Climate Adaptation For A Natural Atoll Island In The Maldives - Predicting The Long-Term Morphological Response Of Coral Islands To Sea Level Rise And The Effect Of Hazard Mitigation Strategies, F. E. Roelvink, G. Masselink, C. Stokes, R. T. Mccall
School of Biological and Marine Sciences
Coral atoll islands, common in (sub)tropical oceans, consist of low-lying accumulations of carbonate sediment produced by fringing coral reef systems and are of great socio-economic and ecological importance. Previous studies have predicted that many atoll islands will become uninhabitable before the end of this century due to sea level rise exacerbating wave-driven flooding. However, the assumption that such islands are morphologically static has been challenged by observations and modeling that show the potential for overwashing and sediment deposition to maintain island freeboard. Reliable long-term predictions of island change and future flood risk, essential for adaptation planning, are, however, lacking. Here, …
Measuring Juvenile Habitat Quality For Fishes And Invertebrates, Benjamin J. Ciotti, Elliot J. Brown, Francesco Colloca, David B. Eggleston, A. Challen Hyman, Olivier Le Pape, Romuald N. Lipcius, Margot A. M. Maathuis, Suzanne S. H. Poiesz, Kenneth A. Rose, Rochelle D. Seitz, Daniele Ventura, Karen E. Van De Wolfshaar
Measuring Juvenile Habitat Quality For Fishes And Invertebrates, Benjamin J. Ciotti, Elliot J. Brown, Francesco Colloca, David B. Eggleston, A. Challen Hyman, Olivier Le Pape, Romuald N. Lipcius, Margot A. M. Maathuis, Suzanne S. H. Poiesz, Kenneth A. Rose, Rochelle D. Seitz, Daniele Ventura, Karen E. Van De Wolfshaar
School of Biological and Marine Sciences
Identifying the role of marine and estuarine habitats in supporting fish and invertebrate populations during vulnerable juvenile life stages is essential to achieve effective conservation and fisheries management. There remains general agreement that: (i) the quality of juvenile habitat is best measured as the contribution of juveniles to adult populations (here “juvenile–adult contribution”) and (ii) this contribution may be measured directly or inferred from habitat-specific abundance, growth and survival. Obtaining effective estimates of juvenile habitat quality using these four metrics, however, is challenging. Through a systematic review of approaches to measure juvenile habitat quality, we critically evaluate current abilities to …
Characterisation Of Tyre Wear Particle Transport From Road Runoff To Sea In Coastal Environments, Florence N.F. Parker-Jurd, Geoffrey D. Abbott, Daniel C. Conley, Cijo M. Xavier, Florian Pohl, Richard C. Thompson
Characterisation Of Tyre Wear Particle Transport From Road Runoff To Sea In Coastal Environments, Florence N.F. Parker-Jurd, Geoffrey D. Abbott, Daniel C. Conley, Cijo M. Xavier, Florian Pohl, Richard C. Thompson
School of Biological and Marine Sciences
Data on the fate of tyre wear particles (TWPs) within aquatic environments is limited. This study quantified TWPs entering estuaries in stormwater drainage and atmospheric fallout, and once they have reached the marine environment, within surface waters and sediments. TWPs were found at concentrations of 0.4 mg/L, 2.55 mg/m2/d, 0.00063 mg/L, and 0.96 g/kg respectively. Samples were partitioned by size to examine the distribution of TWP mass. 80-90% of TWP mass entering marine systems (stormwater and atmospheric fallout) lay between 31-125 µm. Larger particles preferentially accumulated in sediments where ∼50 % of TWP mass was >250 μm, compared to surface …
Tetrazole-Containing Naphthalene Bis-Sulfonamide Keap1-Nrf2 Interaction Inhibitors With Unexpected Binding Modes, Nikolaos D Georgakopoulos, Sandeep K Talapatra, Sharadha Dayalan Naidu, Dina Dikovskaya, Maureen Higgins, Jemma Gatliff, Roxani Nikoloudaki, Marjolein Schaap, Jasmine M Walker, Christopher Wardby, Albena T Dinkova-Kostova, Sarah Harris, Frank Kozielski, Geoff Wells
Tetrazole-Containing Naphthalene Bis-Sulfonamide Keap1-Nrf2 Interaction Inhibitors With Unexpected Binding Modes, Nikolaos D Georgakopoulos, Sandeep K Talapatra, Sharadha Dayalan Naidu, Dina Dikovskaya, Maureen Higgins, Jemma Gatliff, Roxani Nikoloudaki, Marjolein Schaap, Jasmine M Walker, Christopher Wardby, Albena T Dinkova-Kostova, Sarah Harris, Frank Kozielski, Geoff Wells
Peninsula Medical School
Naphthalene bis-sulfonamides are amongst the most studied inhibitors of the interaction between Kelch-like ECH-associated protein-1 (Keap1), a ubiquitination facilitator protein and the nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor associated with diverse cytoprotective responses. The compounds bind to the C-terminal Kelch domain of Keap1 and occupy the Nrf2 binding pocket, causing Nrf2 to accumulate and increase the expression of a battery of antioxidant response element genes. The binding modes of the compounds have been characterised through a series of X-ray crystallography and binding assay studies. In this work we have evaluated a series of symmetric and asymmetric …
Stronger Shores: A Natural Capital Asset And Risk Register For The Northeast England Coastline Part Three: Application Of The Natural Capital Asset And Risk Register To Appraise Options And Assess Benefits Within Flood And Coastal Erosion Risk Management. A Report Has Been Compiled By Staff At The Marine Institute, School Of Biological And Marine Science, University Of Plymouth., Matthew Ashley, Helen Agosti, Tom Mullier, Tom Mullier, Riley Bibaud, Sian Rees
Stronger Shores: A Natural Capital Asset And Risk Register For The Northeast England Coastline Part Three: Application Of The Natural Capital Asset And Risk Register To Appraise Options And Assess Benefits Within Flood And Coastal Erosion Risk Management. A Report Has Been Compiled By Staff At The Marine Institute, School Of Biological And Marine Science, University Of Plymouth., Matthew Ashley, Helen Agosti, Tom Mullier, Tom Mullier, Riley Bibaud, Sian Rees
School of Biological and Marine Sciences
The Part Three report identifies the role and opportunity for application of the Natural Capital Asset and Risk Register evidence, provided in Reports Part One and Two, in appraisal of Nature-based Solutions (NbS) options within Flood and Coastal Erosion Risk Management (FCERM). Interventions applying NbS aim to increase extent and condition of specific habitat assets (ecosystem assets), therefore, considerable environmental benefits, as well as relevant cross-policy objectives are met when NbS are considered as an option. As such, the linked contribution to ecosystem services and associated benefits to people, and where possible economic value, needs to also be documented when …
More Than Just A Magic Trick? Exploring An Audience's Supernatural Attributions For Magicians' Performances, Paul J. Silvia, Sara J. Crasson, Gil Greengross, Gustav Kuhn
More Than Just A Magic Trick? Exploring An Audience's Supernatural Attributions For Magicians' Performances, Paul J. Silvia, Sara J. Crasson, Gil Greengross, Gustav Kuhn
School of Psychology
Performing magicians have long believed that some audience members attribute their magical effects to supernatural methods—to their use of “real magic”. In two samples of adults (n = 412 and 292), we explored personality traits and broader beliefs that might predict supernatural attributions for performance magic. Supernatural attributions were uncommon—many respondents wholly rejected the possibility that magicians' magic was sometimes real—but nevertheless highly variable. In Study 1, a greater belief that magic tricks at least sometimes involve supernatural powers was associated with relatively higher extraversion, higher neuroticism, and lower openness to experience. In Study 2, random forests suggested that supernatural …
How Decontextualised Risk Information Affects Clinicians’ Understanding Of Risk And Uncertainty In Primary Care Diagnosis: A Qualitative Study Of Clinical Vignettes, Alex Burns, Elizabeth Shephard, Raff Calitri, Adrian Mercer, Edmund Jack, Mark Tarrant, Sarah Dean
How Decontextualised Risk Information Affects Clinicians’ Understanding Of Risk And Uncertainty In Primary Care Diagnosis: A Qualitative Study Of Clinical Vignettes, Alex Burns, Elizabeth Shephard, Raff Calitri, Adrian Mercer, Edmund Jack, Mark Tarrant, Sarah Dean
School of Psychology
Background: Decontextualised risk information (DRI) is any information pertaining to diagnosis, which is introduced into a clinical consultation, or a diagnostic thought process, without being requested by the clinician. It can be risk scores, computerised warnings, or laboratory tests or diagnostic imaging requests ordered by other clinicians. It is an increasing, and yet under-researched phenomena in UK primary care. Aim: To investigate how GPs integrate DRI into their clinical decision making and how might they communicate this to patients. Design & setting: Clinical vignettes of cases that involve DRI, designed to increase the diagnostic uncertainty of the case, were presented …
“Being Away From Everything”: Exploring The Importance Of Access To Nature For Individuals Living With Chronic Low Back Pain, Alexander Smith, Kayleigh Wyles, Patricia Schofield, Sam Hughes
“Being Away From Everything”: Exploring The Importance Of Access To Nature For Individuals Living With Chronic Low Back Pain, Alexander Smith, Kayleigh Wyles, Patricia Schofield, Sam Hughes
School of Psychology
Chronic low back pain is a persistent and debilitating condition, and therapeutic outcomes in the long term are generally poor. There is growing evidence to support the ineffectiveness of ‘one-size-fits-all’ pharmacological approaches to pain management. To that end, alternative non-pharmacological therapies such as green social prescribing and time spent in nature are gaining popularity. But it is imperative to understand to what extent these potential interventions are viable by gaining a deeper insight into the lived experiences of the chronic low back pain community. The present qualitative cross-sectional study employed ten semi-structured interviews (9 women, M age = 50.1, M …
Metaphors And Myths: Using The Board Game Dixit To Understand The Autistic Lived Experience, Gray Atherton, Emily Dawson, Liam Cross
Metaphors And Myths: Using The Board Game Dixit To Understand The Autistic Lived Experience, Gray Atherton, Emily Dawson, Liam Cross
School of Psychology
Autism is a condition that takes on many meanings, particularly to those with lived experience. Exploring these meanings is paramount to being able to improve the way that autistic people are treated in the wider world. To further examine autistic lived experience, a new form of qualitative analysis was developed in line with the growing trend of gamification, or creating a game-like condition for exploring different domains. In this paper, we present Dixit-elicitation, a form of qualitative inquiry that uses the popular board game Dixit to interview autistic people about their experiences living with the condition. Themes and subthemes relating …
A Preliminary Study On The Role Of Personal History Of Infectious And Parasitic Diseases On Self-Reported Health Across Countries, Gerit Pfuhl, Filipe Prazeres, Marta Kowal, Toivo Aavik, Beatriz Abad-Villaverde, Reza Afhami, Leonardo Aguilar, Grace Akello, Laith Al-Shawaf, Jan Antfolk, Chiemezie S. Atama, Derya Atamturk Duyar, Roberto Baiocco, Sercan Balım, Carlota Batres, Yakhlef Belkacem, Théo Besson, Adam Bode, Merve Boğa, Jordane Boudesseul, Mahmoud Boussena, Hamdaoui Brahim, Nana Burduli, Ali R. Can, Hakan Cetinkaya, Antonio Chirumbolo, Dimitri Chubinidze, Clément Cornec, Bojana M. Dinić, Seda Dural
A Preliminary Study On The Role Of Personal History Of Infectious And Parasitic Diseases On Self-Reported Health Across Countries, Gerit Pfuhl, Filipe Prazeres, Marta Kowal, Toivo Aavik, Beatriz Abad-Villaverde, Reza Afhami, Leonardo Aguilar, Grace Akello, Laith Al-Shawaf, Jan Antfolk, Chiemezie S. Atama, Derya Atamturk Duyar, Roberto Baiocco, Sercan Balım, Carlota Batres, Yakhlef Belkacem, Théo Besson, Adam Bode, Merve Boğa, Jordane Boudesseul, Mahmoud Boussena, Hamdaoui Brahim, Nana Burduli, Ali R. Can, Hakan Cetinkaya, Antonio Chirumbolo, Dimitri Chubinidze, Clément Cornec, Bojana M. Dinić, Seda Dural
School of Psychology
Objectives: Infectious diseases are often associated with decline in quality of life. The aim of this study is to analyze the relationship between personal history of communicable, i.e., infectious and parasitic diseases and self-rated health. Study design: Secondary analysis of a large dataset multi-country observational study. Methods: We used a four-pronged analysis approach to investigate whether personal history of infectious and parasitic diseases is related to self-reported health, measured with a single item. Results: Three of the four analyses found a small positive effect on self-reported health among those reporting a history of pathogen exposure. The meta-analysis found no support …
What Can Conjuring Tell Us About Cognition? The Future Of The Science Of Magic, Geoff G. Cole, Gustav Kuhn
What Can Conjuring Tell Us About Cognition? The Future Of The Science Of Magic, Geoff G. Cole, Gustav Kuhn
School of Psychology
During the past 20 years a number of articles have appeared within a field that has become known as the “science of magic.” This subdiscipline of psychology posits that the ancient art of conjuring can be used to develop psychological theories and knowledge, and more than 150 peer-reviewed articles have now been published. In the current article, we critically evaluate what can be considered as the three central tenets of the discipline: that the methods used in magic can be incorporated within experimental research, that magicians have particular insight into human cognition and behavior, and that the deconstruction of magic …
Nature Contact And Health Risk Behaviours: Results From An 18 Country Study, Leanne Martin, Mathew P. White, Sabine Pahl, Jon May
Nature Contact And Health Risk Behaviours: Results From An 18 Country Study, Leanne Martin, Mathew P. White, Sabine Pahl, Jon May
School of Psychology
Emerging evidence suggests that residential greenspace is associated with a lower prevalence of health risk behaviours, but it remains unclear whether these effects are generalizable across countries or different types of nature contact. Using representative cross-sectional samples from 18 countries/regions, we examined the associations between two types of nature contact (greenspace, nature visits), current smoking and everyday drinking. After controlling for a range of covariates, greenspace was inversely associated with current smoking and everyday drinking. Visiting natural spaces at least once a week was linked to a lower prevalence of current smoking, but unrelated to everyday drinking. Increasing residential greenspace …
Imagine For Tomorrow, What You Cannot Feel Now – The Role Of Anhedonia In Imagery-Enhanced Behavioral Activation, Max Heise, Julie L. Ji, Jessica Werthmann, Fritz Renner
Imagine For Tomorrow, What You Cannot Feel Now – The Role Of Anhedonia In Imagery-Enhanced Behavioral Activation, Max Heise, Julie L. Ji, Jessica Werthmann, Fritz Renner
School of Psychology
Preliminary evidence suggests that mental imagery-based elaboration of rewarding activities enhances anticipated pleasure, motivation, and behavioral engagement in non-clinical samples, but its effects in individuals experiencing anhedonia (loss of pleasure/interest) is unclear. Study 1 (N = 90) contrasted imagery-enhanced activity scheduling with two scheduling-only control conditions (Reminder/No Reminder Control) in an unselected sample. Study 2 (N = 108) compared imagery-enhanced activity scheduling with two control conditions (Neutral Imagery/Motivational Verbal Reasoning) in individuals experiencing mild to moderate anhedonia. Both studies measured changes in activity appraisal (anticipated pleasure, anticipated reward/mastery, motivation) in the lab, and behavioral engagement across a subsequent 7-day period. …
Transgenerational Plasticity Research: Challenges And Opportunities, Caitlin Mcandry, Alastair J. Wilson, Peter A. Cotton, Manuela Truebano
Transgenerational Plasticity Research: Challenges And Opportunities, Caitlin Mcandry, Alastair J. Wilson, Peter A. Cotton, Manuela Truebano
School of Biological and Marine Sciences
Transgenerational plasticity (TGP) is a type of non-genetic inheritance whereby one generation's environment affects a subsequent generation's phenotype. It can influence the persistence of organisms in stressful climatic conditions through allowing rapid phenotypic change. TGP has been proposed to have the potential to alter an organism's response to selective forces or buffer their effects, yet the interaction of these two processes is neither well understood nor often accounted for via appropriate experimental design. The rapid expansion of TGP research in recent years has led to a lack of clarity surrounding terminology for different phenomena, sometimes undermining the interpretation of research. …
Community, Culture, And Capacity: Transformative Governance In The Gold Coast World Surfing Reserve, Kizzy Beaumont, Andrew Mckinnon, Scott Gillies
Community, Culture, And Capacity: Transformative Governance In The Gold Coast World Surfing Reserve, Kizzy Beaumont, Andrew Mckinnon, Scott Gillies
School of Art, Design and Architecture
Executive summary This report presents findings from interviews and a focus group held in September 2024 with stakeholders involved in the Gold Coast World Surfing Reserve (WSR). Participants shared perspectives on the evolution of the WSR, its governance structures, and its role in balancing surf culture, community needs, and environmental sustainability on one of Australia’s most urbanised coastlines.Participants praised the WSR Stewardship Committee, Council leadership, and strong data partnerships with universities. However, concerns were raised about increasing surf congestion, tourism pressure, development impacts, and the lack of formal legal protections for surf zones. The region’s surf culture was described as …
Balancing Nature And Tradition: Ocean Governance In The Noosa World Surfing Reserve, Kizzy Beaumont, Kirra Molnar, Michael Court
Balancing Nature And Tradition: Ocean Governance In The Noosa World Surfing Reserve, Kizzy Beaumont, Kirra Molnar, Michael Court
School of Art, Design and Architecture
Executive summary This report captures insights from focus groups and interviews held in Noosa in September 2024 as part of ongoing research into Transformative Ocean Governance. Participants shared reflections on the successes and struggles of the Noosa World Surfing Reserve (WSR) and outlined visions for its future.The WSR was praised for its cultural importance, environmental values, and grassroots leadership, but concerns were raised about crowding, tourism pressure, outdated policies, and fragmented governance. Participants highlighted gaps in environmental and surf-amenity data, funding shortages, and limited capacity to engage diverse community voices. Governance overlaps between the WSR, Council, and Biosphere Reserve have …
An Exploration Of The Experiences And Factors Influencing Physical Activity In People With Parkinsons, Heather Hunter
An Exploration Of The Experiences And Factors Influencing Physical Activity In People With Parkinsons, Heather Hunter
School of Health Professions Theses
Abstract:Background: Physical activity plays a crucial role in enhancing the well-being and quality of life of people with Parkinsons. Despite substantial evidence supporting its benefits, people with Parkinson’s struggle to maintain an active lifestyle. This thesis explored the perspective of people with Parkinsons on their engagement in physical activity.Methodology: This research employed a person-centred approach, comprised of three sequential phases. Phase One: A systematic review utilising the JBI approach of meta-aggregation synthesised the best available qualitative evidence of people with Parkinson's' views and preferences regarding physical activity interventions. Phase Two: Constructive Grounded Theory was used to explore the beliefs, attitudes, …
The Role Of A Pelvic Orthotic In The Management Of Chronic Pregnancy-Related Pelvic Girdle Pain: A Feasibility Study And Validation Of A Novel Body Perception Measure, Bradley Halliday
School of Health Professions Theses
Chronic pregnancy-related pelvic girdle pain (PPGP) affects an estimated 10% of post-partum women and is typically recalcitrant to conservative management. One novel option to manage this is a customised Dynamic Elastomeric Fabric Orthosis (DEFO), however, currently non studies have evaluated the clinical and cost-effectiveness or acceptability of this orthotic in post-partum women. Further, the mechanism of action of this orthotic is unknown. One mechanism may be to impart an effect on the disturbed body perception, which preliminary evidence has demonstrated is affected in women with PPGP. Current understanding is limited by an absence of research into women with PPGP and …
Co-Producing Healthcare Guidance For Children And Young People With Ataxia Telangiectasia (A-T) Including The Exploration And Design Of A Home-Based Complex Intervention, Munira Khan
School of Health Professions Theses
This doctoral research aimed to co-produce allied healthcare guidance to improve therapeutic care, self-management, and quality of life for children and young people (CYP) living with ataxia telangiectasia (A-T), a rare and complex neurodegenerative condition. Addressing significant gaps in non-medical care provision, the project was structured into four interrelated work packages (WPs), each contributing original insights and practical tools for families and professionals. WP1 involved a comprehensive scoping review of published and grey literature to map the existing evidence on allied health and nursing management of A-T related symptoms in CYP. The review synthesises 50 sources of evidence and highlighted …
The Revolving Door Of Epilepsy Emergencies, Sarah Lennard
The Revolving Door Of Epilepsy Emergencies, Sarah Lennard
School of Health Professions Theses
This thesis explores the revolving doors of epilepsy emergencies, focusing on the key factors that contribute to repeated attendances at emergency departments (ED) following seizures. The study is based on five peer-reviewed journal articles that provide a comprehensive review of current evidence, risk factors for ED attendance, clinicians' perspectives, and the use of technology in epilepsy management. The research identifies several critical factors influencing ED attendances, including mental health issues, medication adherence, and social determinants such as deprivation and homelessness. The findings highlight the need for integrated care pathways, improved communication between healthcare providers, and targeted interventions for vulnerable populations. …
Pride In Plymouth Archive (Part Of 37 Looe Street Portfolio), Angela Piccini, Sefryn Penrose, Alan Butler
Pride In Plymouth Archive (Part Of 37 Looe Street Portfolio), Angela Piccini, Sefryn Penrose, Alan Butler
School of Art, Design and Architecture
The Pride in Plymouth Community Trust's award-winning community archive contains stories of queer lives over the last 70 years in the city and, on 1 Feb, they will be collaborating with 37 Looe Street to open up the archive and co-curate an exhibition to share these stories
The Role Of Oral Nitrate Reducing Bacteria In Cardiovascular Health: Impacts Of Diet And Exercise, Craig Clarke
The Role Of Oral Nitrate Reducing Bacteria In Cardiovascular Health: Impacts Of Diet And Exercise, Craig Clarke
School of Health Professions Theses
This thesis investigated the important role of oral bacteria in blood pressure regulation and vascular function through the NO3--NO2--NO pathway following exercise or dietary interventions. Study 1 examined the effect of antibacterial mouthwash on the oral microbiome and nitrate metabolism in vegetarians and omnivores. Notable alterations in bacterial composition were observed after mouthwash administration, including reductions in the Prevotella genus (from 27.7% to 9.6%, P = 0.001) and Actinomyces genus (from 9.5% to 5.7%, P = 0.001), along with decreases in Prevotella melaninogenica (from 18.1% to 6.2%, P = 0.001) and Rothia dentocariosa (from 0.09% to 0.04%, P = 0.001). …
A Critical Exploration Of Social Transformation Through Occupation, Miranda Cunningham
A Critical Exploration Of Social Transformation Through Occupation, Miranda Cunningham
School of Health Professions Theses
Background: In occupational therapy and occupational science, scholars and practitioners advocate for a stronger focus on social transformation. However, there is limited evidence on how occupation-based interventions contribute to addressing inequalities and fostering change for marginalised populations. Methods: This study applied critical occupational science and realist theoretical frameworks to examine the use of arts-based occupations for social transformation. It comprised three strands: (1) a narrative review of arts-based occupations in social change, (2) a realist review of participatory photography, and (3) a realist evaluation of a socially engaged art group in primary schools. Findings: Arts-based occupations have been employed by …
Rhce Genotyping Using Next Generation Sequencing:Allele Specific Reference Sequences, Wajnat A. Tounsi, Amr J. Halawani, Kelly A. Sillence, Michele Kiernan, Neil D. Avent, Tracey Madgett
Rhce Genotyping Using Next Generation Sequencing:Allele Specific Reference Sequences, Wajnat A. Tounsi, Amr J. Halawani, Kelly A. Sillence, Michele Kiernan, Neil D. Avent, Tracey Madgett
School of Biomedical Sciences
BackgroundThe Rh blood group system (ISBT004) is encoded by two homologous genes, RHD and RHCE. Polymorphism in these two genes gives rise to 56 antigens, which are highly immunogenic and clinically significant. This study extended previous work on the establishment of RHD allele specific reference sequences using next generation sequencing (NGS) with the Ion Personal Genome Machine (Ion PGM) to sequence the complete RHCE gene.Study Design and MethodsGenomic DNA (gDNA) samples (n = 87) from blood donors of different serologically predicted genotypes including R1R1 (DCe/DCe), R2R2 (DcE/DcE), R1R2 (DCe/DcE), R2RZ (DcE/DCE), R1r (DCe/dce), R2r (DcE/dce), R0r (Dce/dce), rr (dce/dce), r'r …
The Effect Of Exercise Training On Blood Lipids: A Systematic Review And Meta-Analysis, Neil A. Smart, David Downes, Tom Van Der Touw, Swastika Hada, Gudrun Dieberg, Melissa J. Pearson, Mitchell Wolden, Nicola King, Stephen P.J. Goodman
The Effect Of Exercise Training On Blood Lipids: A Systematic Review And Meta-Analysis, Neil A. Smart, David Downes, Tom Van Der Touw, Swastika Hada, Gudrun Dieberg, Melissa J. Pearson, Mitchell Wolden, Nicola King, Stephen P.J. Goodman
School of Biomedical Sciences
Background: Dyslipidemia is a primary risk factor for cardiovascular disease (CVD). Exercise training (EXTr) improves some lipid markers but not others; the literature is dated and analyses may be underpowered. Objectives: To clarify which lipid markers are altered with ExTr and establish if information size had yet reached futility. Methods: We conducted a systematic review/meta-analysis, with meta-regression, to establish expected effect size in lipid profile with aerobic (AT), resistance (RT) and combined (CT = AT + RT) ExTr. We conducted trial sequence analysis (TSA) to control for type I and II error and establish if information size had reached futility. …
The Micronutrient Gap: Understanding Modern Dietary Shortfalls, Kathy Redfern
The Micronutrient Gap: Understanding Modern Dietary Shortfalls, Kathy Redfern
School of Biomedical Sciences
Nutrition science is a relatively young discipline, yet our understanding of how diet impactshealth, wellbeing, and performance has grown significantly over the past century. Despite thissurge in research and heightened public awareness, many modern diets in developed nationsare falling short in key micronutrients such as vitamin D, vitamin B12, and folic acid (1). Thesetrends are driven by a range of factors, including rising consumption of ultra-processed foods(UPFs), declining nutrient density in produce, reduced sunlight exposure, and chronic stress.