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Articles 150811 - 150840 of 157171
Full-Text Articles in Entire DC Network
Anemia, Hematinic Deficiencies, Hyperhomocysteinemia, And Serum Gastric Parietal Cell Antibody Positivity In Oral Lichen Planus Patients With Macrocytosis, Chung-Pin Chiang, Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, Andy Sun
Anemia, Hematinic Deficiencies, Hyperhomocysteinemia, And Serum Gastric Parietal Cell Antibody Positivity In Oral Lichen Planus Patients With Macrocytosis, Chung-Pin Chiang, Julia Yu-Fong Chang, Yu-Hsueh Wu, Yi-Pang Lee, Yi-Ping Wang, Andy Sun
Journal of Dental Sciences
Abstract Background/purpose Macrocytosis is defined as having the mean corpuscular volume (MCV) ≥ 100 fL. This study evaluated whether 36 oral lichen planus (OLP) patients with macrocytosis (macrocytosis/OLP patients) had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than 588 healthy control subjects or 588 OLP patients. Materials and methods Complete blood count, serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 36 macrocytosis/OLP patients, 588 OLP patients, and 588 healthy control subjects were measured and compared. Results We found that 66.7 %, 8.3 %, 91.7 %, 0.0 %, 94.4 …
Innovative 3d-Printed Dental Teaching Model For Root Canal Treatment Simulation, Szu-Yu Chen, Yu-Chiao Wu, Jia-Rong Wu, Che-Yi Lin, Yi-Jen Hung, Tsai-Wang Huang, Yi-Shing Shieh
Innovative 3d-Printed Dental Teaching Model For Root Canal Treatment Simulation, Szu-Yu Chen, Yu-Chiao Wu, Jia-Rong Wu, Che-Yi Lin, Yi-Jen Hung, Tsai-Wang Huang, Yi-Shing Shieh
Journal of Dental Sciences
Abstract Background/purpose Effective endodontic education requires realistic models for simulating clinical procedures, particularly working length (WL) determination using electronic apex locators (EALs). Traditional training methods using extracted or plastic teeth lack standardization, realism, and compatibility with EALs. This study aimed to develop and evaluate a 3D-printed tooth model with conductive properties that allows realistic and standardized training in EAL-based WL determination. Materials and methods Custom 3D-printed teeth with two distinct working lengths (20.0 mm and 21.9 mm) were designed using cone-beam computed tomography (CBCT) and 3D scanning. Each tooth was embedded in two types of conductive media—tap water and saline. …
Effects Of Varying Anteroposterior Craniodentofacial Morphologies On Three-Dimensional Smile Variables, Hsin-Chung Cheng, Patcharamas Banditsaowapak
Effects Of Varying Anteroposterior Craniodentofacial Morphologies On Three-Dimensional Smile Variables, Hsin-Chung Cheng, Patcharamas Banditsaowapak
Journal of Dental Sciences
Abstract Background/purpose Research regarding clinical facial assessment has increasingly shifted toward three-dimensional (3D) methods. This cross-sectional study examined the associations between 3D smile variables and two anteroposterior craniodentofacial morphologies (overjet [OJ] and point-A-nasion-point-B angle [ANB]) and quantified facial soft tissue displacement during the transition from rest to posed smiles. Materials and methods This study included 119 participants aged 18–30 years. They were divided into three OJ groups (0–4 mm, >4 mm, and <0 mm) and three ANB groups (0°–4°, >4°, and <0°). 3D facial images were taken at rest and during smiling. Subsequently, landmark positions were analyzed. Linear, angular, and proportional measurements were obtained, and landmark displacements were measured. Results Of the 257 3D soft tissue variables considered, 41 differed significantly among the 3 OJ groups, and 46 differed significantly among the 3 ANB groups during smiling. The intercommissural width measured during smiling in ANB group 1 was more significant than that in the other two groups. Labiomental angles were larger in ANB group 3 at rest and during smiling, whereas the angle at rest was smaller in OJ group 2. Lower lip movements in OJ group 3 and ANB group 3 were more restricted than those in groups 1 and 2. Conclusion OJ and ANB primarily affect soft tissue landmarks during smiling. A large OJ may lead to a deep labiomental sulcus, whereas a negative ANB may result in a flattened sulcus. Reverse OJ and Class III skeletal malocclusion affect the lower lip by restricting its movement.
A Scientometric Study On Wnt And Notch Signaling Pathways In Oral Potentially Malignant Disorders And Oral Cancer, Xiaoliang Luo, Yiwen Deng, Hao Wu
A Scientometric Study On Wnt And Notch Signaling Pathways In Oral Potentially Malignant Disorders And Oral Cancer, Xiaoliang Luo, Yiwen Deng, Hao Wu
Journal of Dental Sciences
Abstract Background/purpose Accumulating evidence indicates that aberrant activation of certain cellular signaling pathways occurs during the development and progression of oral cancer. The purpose of this study was to analyze the scientometric characteristics of Wnt and Notch pathways in oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC). Materials and methods All the papers on Wnt and Notch pathways in OPMD/OSCC were comprehensively retrieved from the Scopus database. Results A total of 301 and 169 papers on Wnt and Notch signaling pathway in the field of OPMD/OSCC were retrieved, respectively. As for Wnt pathway in OPMD/OSCC research, distinctive …
Accelerated Senescence Animal Models And Application In Dentistry: A Scoping Review, Siwei Wang, Jiayu Mou, Jiarui Jiang, Qi He, Mulan Qahar, Daniele De Santis, Fang Qi, Guangchao Xu, Jianguo Liu
Accelerated Senescence Animal Models And Application In Dentistry: A Scoping Review, Siwei Wang, Jiayu Mou, Jiarui Jiang, Qi He, Mulan Qahar, Daniele De Santis, Fang Qi, Guangchao Xu, Jianguo Liu
Journal of Dental Sciences
Abstract Accelerated senescence models are increasingly utilized in aging research; however, their application in dental studies remains relatively limited. This scoping review investigates the use of these models within oral research. A systematic search of PubMed and Web of Science was conducted, following PRISMA-ScR guidelines and registered with the Open Science Framework, to identify relevant in vivo studies published between January 2020 and March 2025. Eligible studies involved accelerated senescence animal models in oral health contexts. Data were extracted on animal types, induction methods, aging biomarkers (e.g., P53, P21, P16, SA-β-gal), and outcomes for narrative synthesis. From 377 screened articles, …
Mir-376a/Neuropilin-1 Axis Mediates The Cancer Stemness In Oral Squamous Cell Carcinoma-An In Vitro Study, Yu-Chao Chang, Yi-Wen Liao, Cheng-Chia Yu, Heng-Yi Liao
Mir-376a/Neuropilin-1 Axis Mediates The Cancer Stemness In Oral Squamous Cell Carcinoma-An In Vitro Study, Yu-Chao Chang, Yi-Wen Liao, Cheng-Chia Yu, Heng-Yi Liao
Journal of Dental Sciences
Abstract Background/purpose The incidence of oral cancer has been steadily increased over the years. Recent researches indicated that exploring oral cancer stem cells (CSCs) characterized by self-renewal, pluripotency, and aggressiveness have emerged as a promising strategy for predicting oral squamous cell carcinoma (OSCC) recurrence and metastasis. Previous studies have demonstrated that microRNAs regulate cancer stemness. However, the mechanisms that miR-376a/neuropilin-1 (NRP1) axis influences CSC traits have not yet been fully understood. Therefore, an in-depth investigation was conducted in this study. Materials and methods miR-376a expression in CSCs derived from OSCC cell line SAS was quantified by quantitative real-time polymerase chain …
Career Choices In Graduates From The Taipei Third Girls High School In 1936 – With Special Emphasis On Those Hoping To Study Dentistry, Feng-Chou Cheng, Ling-Hsia Wang, Chun-Pin Chiang
Career Choices In Graduates From The Taipei Third Girls High School In 1936 – With Special Emphasis On Those Hoping To Study Dentistry, Feng-Chou Cheng, Ling-Hsia Wang, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
A Novel Surgical Approach For Benign Deep Lobe Of Parotid Gland Tumors: Utilizing The Santorini Fissure, Hao Lu, Shengwen Liu, Wanlin Xu, Wenjun Yang
A Novel Surgical Approach For Benign Deep Lobe Of Parotid Gland Tumors: Utilizing The Santorini Fissure, Hao Lu, Shengwen Liu, Wanlin Xu, Wenjun Yang
Journal of Dental Sciences
No abstract provided.
Evaluating The Impact Of Varying Post Angulations On The Fracture Resistance Of Maxillary Incisors Restored With Polyethylene Fiber Posts, Chung-Ming Liu, Christine Rovani, Nurhayaty Natsir, Irfan Yamin, Aries Trilaksana, Li-Rong Kuo, Bai-Hung Huang
Evaluating The Impact Of Varying Post Angulations On The Fracture Resistance Of Maxillary Incisors Restored With Polyethylene Fiber Posts, Chung-Ming Liu, Christine Rovani, Nurhayaty Natsir, Irfan Yamin, Aries Trilaksana, Li-Rong Kuo, Bai-Hung Huang
Journal of Dental Sciences
Abstract Background/purpose Restoring anterior teeth requiring angulation correction remains clinically challenging. Polyethylene fiber posts have been introduced, offering superior adaptability within the root canal and improved aesthetics. However, the effect of varying degrees of post angulation on the fracture resistance of restored teeth has not been thoroughly investigated. This study aimed to evaluate the fracture resistance of maxillary incisors restored using polyethylene fiber posts at varying angulations. Materials and methods Thirty-two extracted incisors were selected according to the study criteria. Root canal treatment and gutta-percha removal were performed to prepare for polyethylene fiber posts. All study samples were subsequently divided …
The Potential Effect Of Photobiomodulation On Oral Mucositis Induced By Head And Neck Radio-Chemotherapy: A Literature Review, Rashin Bahrami, Shahriar Eftekharian, Raha Jafarieh, Maryam Pourhajibagher, Abbas Bahador
The Potential Effect Of Photobiomodulation On Oral Mucositis Induced By Head And Neck Radio-Chemotherapy: A Literature Review, Rashin Bahrami, Shahriar Eftekharian, Raha Jafarieh, Maryam Pourhajibagher, Abbas Bahador
Journal of Dental Sciences
Abstract Oral mucositis (OM) is a common side effect of head and neck radio-chemotherapy. It manifests as painful, ulcerative lesions in the oral mucosa, significantly impairing essential functions such as eating, speaking, and maintaining oral hygiene. It finally has adverse effects on the patient's quality of life. Photobiomodulation therapy (PBMT) has emerged as a promising non-invasive modality for preventing and treating OM. Due to controversy among the results of studies, this literature review synthesizes findings from recent randomized controlled trials that evaluated the use of PBMT in adult and pediatric cancer patients. This review also highlights the mechanisms, clinical efficacy, …
Limited Field-Of-View Cone-Beam Computed Tomography For Resolving Working Length Discrepancy Between Electronic Apex Locator And Periapical Radiography, He Liu, Ya Shen
Limited Field-Of-View Cone-Beam Computed Tomography For Resolving Working Length Discrepancy Between Electronic Apex Locator And Periapical Radiography, He Liu, Ya Shen
Journal of Dental Sciences
No abstract provided.
Microrna Let-7a Mitigates The Progression Of Oral Submucous Fibrosis By Targeting High-Mobility Group At-Hook 2, Hui-Wen Yang, Chih-Yuan Fang, Shih-Chi Chao, Yi-Wen Liao, Cheng-Chia Yu, Yu-Wei Chiu
Microrna Let-7a Mitigates The Progression Of Oral Submucous Fibrosis By Targeting High-Mobility Group At-Hook 2, Hui-Wen Yang, Chih-Yuan Fang, Shih-Chi Chao, Yi-Wen Liao, Cheng-Chia Yu, Yu-Wei Chiu
Journal of Dental Sciences
Abstract Background/purpose Oral submucous fibrosis (OSF) is an irreversible fibrotic disorder of the oral cavity with a high potential for malignant transformation. MicroRNA lethal-7a (let-7a) has been recognized as a key antifibrotic regulator, but its specific role in OSF remains unknown. Therefore, this study aimed to elucidate the functional significance and the molecular mechanism of let-7a in OSF progression. Materials and methods The expression of let-7a was quantified by real-time quantitative polymerase chain reaction in fibrotic buccal mucosal fibroblasts (fBMFs) isolated from OSF lesions and patient–matched non-fibrotic BMFs (BMFs). Myofibroblastic characteristics were evaluated using collagen-gel contraction, Transwell migration, and wound-healing …
Evaluation Of An Anti-Snoring Device Featuring A Ni–Ti Alloy Elastic Linkage In A Simulated Clinical Environment, Chun-Pin Lin, Ming-Sung Hsu, Tung-Lin Tsai, Shih-Jung Cheng, Yu-Sheng Lin, Li-Wen Weng
Evaluation Of An Anti-Snoring Device Featuring A Ni–Ti Alloy Elastic Linkage In A Simulated Clinical Environment, Chun-Pin Lin, Ming-Sung Hsu, Tung-Lin Tsai, Shih-Jung Cheng, Yu-Sheng Lin, Li-Wen Weng
Journal of Dental Sciences
Abstract Background/purpose Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder that is often treated by mandibular advancement devices (MADs). However, conventional MADs are frequently associated with discomfort, rigidity, and limited patient compliance. This study aimed to design and evaluate a custom-made anti-snoring device featuring a nickel-titanium (Ni–Ti) alloy elastic connector to improve comfort, durability, and clinical performance. Materials and methods The device consisted of dual-layer upper and lower trays and was connected via Ni–Ti alloy rods. Finite element analysis (FEA) was conducted to compare the stress and deformation characteristics of three materials (Ni–Ti, stainless steel, and polycarbonate). Fatigue …
Unveiling The Characteristics And Surface Modification Of Titanium, Zirconia, And Polyetheretherketone Dental Implants, Shinn-Jyh Ding, Yu-Hsuan Cheng, Chun-Cheng Chen
Unveiling The Characteristics And Surface Modification Of Titanium, Zirconia, And Polyetheretherketone Dental Implants, Shinn-Jyh Ding, Yu-Hsuan Cheng, Chun-Cheng Chen
Journal of Dental Sciences
Abstract Titanium, zirconia, and polyetheretherketone (PEEK) are among the most extensively studied materials in dental implantology, each offering unique properties that influence their clinical performance. This review systematically compared their physicochemical characteristics and their in vitro and in vivo behaviors. It also evaluated various surface modification techniques designed to enhance osseointegration and antibacterial properties. Titanium, recognized as the gold standard, is renowned for its exceptional mechanical strength and superior osseointegration, although it is associated with a higher risk of peri-implantitis. Zirconia, valued for its excellent aesthetics and compatibility with soft tissues, presents a promising metal-free alternative; however, its brittleness can …
Evaluating The Impact Of Orthognathic Surgery On Mental Health, Function, And Quality Of Life, Chia Tze Kao, Chuan-Yi Kao, Tsui-Hsein Huang, Chun-Te Ho, Yi Hsien Hsieh
Evaluating The Impact Of Orthognathic Surgery On Mental Health, Function, And Quality Of Life, Chia Tze Kao, Chuan-Yi Kao, Tsui-Hsein Huang, Chun-Te Ho, Yi Hsien Hsieh
Journal of Dental Sciences
Abstract Background/Purpose Prior research highlights the psychological burden of facial deformities, yet there remains a lack of evidence regarding which postoperative variables most strongly influence mental well-being. This study explored the relationship between psychological status, physical function, and quality of life in patients with craniofacial malocclusion undergoing orthognathic surgery, aiming to identify predictors of psychiatric referral and patient satisfaction. Materials and methods A retrospective, single-center study was conducted at Chung Shan Medical University Hospital, reviewing 60 de-identified medical records of patients who received orthognathic surgery between 2019 and 2024. Variables assessed included pain, oral function, anxiety, depression, body image, facial …
Corylin Attenuates Oral Squamous Cell Carcinoma Progression Through C-Myc Inhibition, Chin-Chuan Chen, Chi-Yuan Chen, Li-Fang Chou, Chau-Ting Yeh, Yi-Tsen Liu, Yu-De Chu, Hsin-Wei Lin, Kai-Yin Chen, Cheng-Chia Yu, Tong-Hong Wang
Corylin Attenuates Oral Squamous Cell Carcinoma Progression Through C-Myc Inhibition, Chin-Chuan Chen, Chi-Yuan Chen, Li-Fang Chou, Chau-Ting Yeh, Yi-Tsen Liu, Yu-De Chu, Hsin-Wei Lin, Kai-Yin Chen, Cheng-Chia Yu, Tong-Hong Wang
Journal of Dental Sciences
Abstract Background /purpose : Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy of the head and neck, with current treatment options often limited by low efficacy and drug resistance. In this study, we investigated the anticancer activity and underlying mechanisms of corylin, a flavonoid extracted from Psoralea corylifolia, in OSCC. Materials and methods OSCC cell lines (SAS and OECM1) were treated with corylin, and its effects on cell proliferation, migration, and invasion were assessed using cell function assays. Flow cytometry and DiOC6/PI staining were performed to analyze cell cycle progression and apoptosis, while Western blotting was used to …
Brain Activation Generated By Periodontal Initial Treatment, Kosuke Muraoka, Masafumi Oda, Kenichi Yoshino, Tatsurou Tanaka, Masaki Morishita, Taiji Nakamura, Shino Yamaguchi, Kazuo Sonoki, Yasuhiro Morimoto, Keisuke Nakashima, Shuji Awano
Brain Activation Generated By Periodontal Initial Treatment, Kosuke Muraoka, Masafumi Oda, Kenichi Yoshino, Tatsurou Tanaka, Masaki Morishita, Taiji Nakamura, Shino Yamaguchi, Kazuo Sonoki, Yasuhiro Morimoto, Keisuke Nakashima, Shuji Awano
Journal of Dental Sciences
Abstract Background/purpose There is a close relationship between the dental field and the cognitive function of the brain. The aim of this research was to examine the effect of periodontal initial treatment on brain functional activity. Materials and methods The subjects were 16 patients with periodontitis. After informed consent was obtained, periodontal initial treatment included brushing instruction, scaling and root planing. No occlusal adjustments were conducted. Periodontal examination and functional magnetic resonance imaging (fMRI) were performed at the initial visits and subsequent reassessments. Results Periodontal tissue improved significantly after periodontal initial treatment. From fMRI testing, during both the language and …
Beyond Dental Radiographs, A Radiomics-Based Study For The Classification Of Caries Extension And Depth, Gianrico Spagnuolo, Niccolò Giuseppe Armogida, Francesca Angelone, Parisa Soltani, Luigi Esposito, Mario Sansone, Sandro Rengo, Francesco Amato, Carlo Rengo, Alfonso Maria Ponsiglione
Beyond Dental Radiographs, A Radiomics-Based Study For The Classification Of Caries Extension And Depth, Gianrico Spagnuolo, Niccolò Giuseppe Armogida, Francesca Angelone, Parisa Soltani, Luigi Esposito, Mario Sansone, Sandro Rengo, Francesco Amato, Carlo Rengo, Alfonso Maria Ponsiglione
Journal of Dental Sciences
Abstract Background/purpose Traditional caries detection relies on visual and radiographic analysis. While deep learning has been applied to classify caries extent, no studies classify caries depth using radiomic features in intraoral photographic images. This study evaluated a radiomics-based approach with machine learning (ML) to classify caries extent and depth, traditionally assessed via radiographs, using intraoral photographs. Materials and methods Standardized intraoral photographs were taken with a Nikon D7500 and Macro Flash MF-R76. Only images of healthy teeth or carious lesions were included. Images were resized, segmented with Labelme, and classified using ICDAS and E-D scales. Data augmentation increased sample size. …
Influence Of The Coronavirus Pandemic On Domiciliary Dental Care And Associated Problems In Japan -A Questionnaire Study, Yoshiyuki Hagiwara, Hiroyasu Yasuda, Keisuke Seki, Daisuke Akita, Kenji Ito, Tetsuo Ohyama
Influence Of The Coronavirus Pandemic On Domiciliary Dental Care And Associated Problems In Japan -A Questionnaire Study, Yoshiyuki Hagiwara, Hiroyasu Yasuda, Keisuke Seki, Daisuke Akita, Kenji Ito, Tetsuo Ohyama
Journal of Dental Sciences
Abstract Background/purpose The coronavirus disease (COVID-19) pandemic had a major impact on many patients receiving domiciliary dental care, and many services were suspended. This study aimed to assess the interruption of domiciliary dental care due to COVID-19 and the oral and general condition of patients whose care was interrupted. Materials and methods We randomly selected 1500 dentists providing domiciliary dental care in the Tokyo area and mailed them a questionnaire about the impact of COVID-19 on domiciliary dental care. The questionnaire investigated the level of interruption in care, infection prevention measures, oral care status, the motivation and psychological state of …
Serotonin Promotes Lip Sensory Recovery After Inferior Alveolar Nerve Transection Via Histone Serotonylation, Li Ye, Suning Mao, Gaowei Zhang, Zhongkai Ma, Pingchuan Ma, Chunjie Li
Serotonin Promotes Lip Sensory Recovery After Inferior Alveolar Nerve Transection Via Histone Serotonylation, Li Ye, Suning Mao, Gaowei Zhang, Zhongkai Ma, Pingchuan Ma, Chunjie Li
Journal of Dental Sciences
Abstract Background/purpose Sensory impairment due to Inferior alveolar nerve injury in mandibular tumor ablation severely impairs the survivors’ quality of life. This study explored the role of serotonin in lip sensory recovery after inferior alveolar nerve transection. Materials and methods We established an in vivo inferior alveolar nerve transection model using C57BL/6J mice and an in vitro model of primary neurons in trigeminal ganglia. Serotonin or transglutaminase 2 inhibitor (GK921) were administrated to mice or neurons. The degree of lip sensory recovery was confirmed by quantitative sensory testing with Von Frey filaments. The axonal length was directly measured under optical …
Lunar Life Drives Jawbone Formation, Kotaro Sato, Naoka Kouyama, Shinya Akatsuka, Yashiro Motooka, Qinhong Wang, Hideharu Hibi, Shinya Toyokuni
Lunar Life Drives Jawbone Formation, Kotaro Sato, Naoka Kouyama, Shinya Akatsuka, Yashiro Motooka, Qinhong Wang, Hideharu Hibi, Shinya Toyokuni
Journal of Dental Sciences
Abstract Background/purpose The Japan Aerospace Exploration Agency bred mice in the “Kibo” module on the International Space Station to clarify the effects of gravity changes on the body. We determined the effects of lunar gravity (partial gravity, 1/6G) on the jawbone and elucidated its relationship with the oral cavity. Materials and methods Mandibular bones of C57BL/6J male mice from the Kibo group (1/6G) and the Earth group (1G) were obtained. Ribonucleic acid was extracted from the samples; microarray and gene set enrichment analysis (GSEA) were performed; bone structure and histology were evaluated via micro-computed tomography, immunohistochemistry, and specific staining. Results …
Association Between Dental Scaling And The Lower Risk Of Oral Cancer: A Population-Based Nested Case-Control Study, Yu-Chao Chang, Ying-Ting Yeh, Chiao-Wen Lin, Ping-Ju Chen, Chia-Yi Lee, Yu-Hsun Wang, Shun-Fa Yang, Chao-Bin Yeh
Association Between Dental Scaling And The Lower Risk Of Oral Cancer: A Population-Based Nested Case-Control Study, Yu-Chao Chang, Ying-Ting Yeh, Chiao-Wen Lin, Ping-Ju Chen, Chia-Yi Lee, Yu-Hsun Wang, Shun-Fa Yang, Chao-Bin Yeh
Journal of Dental Sciences
Abstract Background/purpose Oral cancer is a common malignancy that associates with oral inflammatory reactions. Dental scaling can effectively reduce periodontal inflammation to facilitate oral health. This may contribute to a less conducive environment for oral cancer initiation and progression. The aim of this study was to investigate the association between dental scaling and oral cancer. Materials and methods A retrospective nested case-control study was conducted by using Taiwanese Longitudinal Health Insurance Database. This study captured patients with oral cancer identified from the cancer registry. Each oral cancer patient was matched with eight non-oral cancer controls based on age and sex. …
Recombinant Human Fibroblast Growth Factor-2 Promotes Surgical-Wound Healing In The Rat Gingiva, Yasunori Yoshinaga, Naoki Maruo, Kimiko Ohgi, Hiroaki Yamato, Nanako Tsuchimochi, Masanobu Nakagami, Ryuji Sakagami
Recombinant Human Fibroblast Growth Factor-2 Promotes Surgical-Wound Healing In The Rat Gingiva, Yasunori Yoshinaga, Naoki Maruo, Kimiko Ohgi, Hiroaki Yamato, Nanako Tsuchimochi, Masanobu Nakagami, Ryuji Sakagami
Journal of Dental Sciences
Abstract Background/purpose Fibroblast growth factor-2 (FGF-2) has been shown to promote periodontal tissue regeneration in clinical settings. However, reports on the effects of FGF-2 on soft-tissue wound healing after periodontal surgery are scarce. This study aimed to investigate the effects of FGF-2 on gingival wound healing. Materials and methods Seven-week-old male Sprague–Dawley rats were divided into three groups. Each group included 15 rats, with five animals in each experimental period. Five untreated rats were used as the no-treated group. Incisions were made bilaterally in the palatal mucosa from the mesial corner of the maxillary first molar up to the incisor, …
A Scientometric Study On Research Trends And Characteristics Of Halitosis, Xiaole Liu, Ye Zhang, Qingqing Liu, Chengsu Hou, Ling Xu
A Scientometric Study On Research Trends And Characteristics Of Halitosis, Xiaole Liu, Ye Zhang, Qingqing Liu, Chengsu Hou, Ling Xu
Journal of Dental Sciences
Abstract Background/purpose Halitosis is a condition characterized by unpleasant odors originating from the oral cavity. The purpose of this study was to analyze the scientometric characteristics and research trends of halitosis. Materials and methods All the papers on halitosis were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and after 2015 in the analysis of research trends. Results There were 1252 papers on halitosis, with total citations of 26,932 and the h index of 76. Poor oral hygiene, periodontitis, periodontal disease, gingivitis, dental caries, xerostomia, periodontics, and smoking were halitosis-related conditions. The trend …
Benchmarking Multimodal Large Language Models On The Dental Licensing Examination: Challenges With Clinical Image Interpretation, Yuichi Mine, Shota Okazaki, Tsuyoshi Taji, Hiroyuki Kawaguchi, Naoya Kakimoto, Takeshi Murayama
Benchmarking Multimodal Large Language Models On The Dental Licensing Examination: Challenges With Clinical Image Interpretation, Yuichi Mine, Shota Okazaki, Tsuyoshi Taji, Hiroyuki Kawaguchi, Naoya Kakimoto, Takeshi Murayama
Journal of Dental Sciences
Abstract Background /purpose: Large language models (LLMs) have been studied in text-based healthcare tasks, but their performance in multimodal dental applications has not yet been fully explored. This study evaluated the performance of four multimodal LLMs on dental licensing examination questions with both text-only and visually-based components. Materials and methods Four multimodal LLMs, ChatGPT-4o (4o), OpenAI o1 (o1), Claude 3.5 Sonnet (Sonnet), and Gemini 2.0 Flash Thinking Experimental (Gemini), were tested on 353 questions from the 2024 Japanese National Dental Examination, including 204 text-only and 149 visually-based questions spanning 17 dental specialties. A zero-shot approach was used without prompt engineering. …
Γ-Mangostin Mitigates Impaired Wound Healing And Pyroptosis In Human Gingival Fibroblasts Induced By Advanced Glycation End Products, Chao-Yen Huang, Pei-Yin Chen, Min Yee Ng, Yi-Wen Liao, Cheng-Chia Yu, Szu-Han Chen
Γ-Mangostin Mitigates Impaired Wound Healing And Pyroptosis In Human Gingival Fibroblasts Induced By Advanced Glycation End Products, Chao-Yen Huang, Pei-Yin Chen, Min Yee Ng, Yi-Wen Liao, Cheng-Chia Yu, Szu-Han Chen
Journal of Dental Sciences
Abstract Background/purpose The incidence of diabetes mellitus (DM) has gradually increased in recent years. DM and its complications impose a substantial burden on healthcare systems. Chronic hyperglycemia results in the accumulation of advanced glycation end products (AGEs), which in turn elevate oxidative stress and inflammation, thereby contributing to diabetic complications, including impaired wound healing. γ-Mangostin, a mangostin isolated from the pericarp of mangosteen fruit, has been reported to possess antioxidant and anti-inflammatory properties. Our study aimed to investigate the effects of γ-mangostin on AGEs-induced impairment of wound healing and inflammaging. Materials and methods Human gingival fibroblasts (HGFs) were isolated from …
A Japanese Dentist Immigrant Described By The Writer, Chihei Nakamura, During The Japanese Colonial Period, Feng-Chou Cheng, Ling-Hsia Wang, Wen-Hsun Chang, Chun-Pin Chiang
A Japanese Dentist Immigrant Described By The Writer, Chihei Nakamura, During The Japanese Colonial Period, Feng-Chou Cheng, Ling-Hsia Wang, Wen-Hsun Chang, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
The Story Of A Radiation Technician Covering Dental Radiology In Taiwan During The Japanese Colonial Period - Mr. Sakae Kawahara (1904–1943), Feng-Chou Cheng, Ling-Hsia Wang, Yu-Ting Hu, Chun-Pin Chiang
The Story Of A Radiation Technician Covering Dental Radiology In Taiwan During The Japanese Colonial Period - Mr. Sakae Kawahara (1904–1943), Feng-Chou Cheng, Ling-Hsia Wang, Yu-Ting Hu, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Exploring The Framework Of Professional Subspecialties For Dental Technicians, Ching-Shuen Wang, Feng-Chou Cheng, Wei-Chun Lin, Chun-Pin Chiang
Exploring The Framework Of Professional Subspecialties For Dental Technicians, Ching-Shuen Wang, Feng-Chou Cheng, Wei-Chun Lin, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
Digital Workflow For Full-Arch Immediate Loading: Dynamic Navigation And 3d Printing Fixed Dental Prostheses, Cheng-Chung Lin, Han-Wei Lin, Yu-Chieh Lin, Wei-Chun Lin
Digital Workflow For Full-Arch Immediate Loading: Dynamic Navigation And 3d Printing Fixed Dental Prostheses, Cheng-Chung Lin, Han-Wei Lin, Yu-Chieh Lin, Wei-Chun Lin
Journal of Dental Sciences
No abstract provided.