Digital Commons Network^™

Optimizing Death To Effectuate Deterrence, Lucas Brolin

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Remedying Public Disapproval Of The Supreme Court: Expanding The Role Of The Public Information Officer, Brown James

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Political Deepfakes And The Limits Of The Law, R. George Wright

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The Dilemmas Of The 2023 Merger Guidelines, Aurelian Portuese

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The End Is Still To Come: How The Law’S Interaction With Digital Replicas And Derivative Digital Replicas Will Shape The Future, Spencer Kweskin

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The World’S Oldest Profession Needs New Answers, Ariana Zaimi

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The Case For Climate Refugee Protection, Nicole Theriot

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Design Of A Laser Writing Instrument For Selective Local Patterning Of Vanadium Oxide Phases, Junjie Li

Faculty Publications

No abstract provided.

An Analysis Of The Effectiveness Of Informational Interviews On Biomedical Engineering Students' Professional Growth, Career Preparedness, And Networking Skills Development, Thomas H. Mcgehee, Bryce Williams, Alyssandra Navarro, Mostafa Elsaadany

2025 Research Poster Competition

Bone fractures and complete joint replacements are becoming more common, primarily because of accidents and age-related issues. Conventional solutions to treat these orthopedic injuries involve inert metal alloys to correct bone fractures until the healing process is complete, where a secondary revision surgery is then required to remove the implant. Issues regularly associated with these solutions include stress shielding, bone resorption, infection, inflammation, and implant loosening. Magnesium (Mg)-based nanocomposites offer promising potential as an alternative to commonly used metal alloys because of their favorable mechanical properties and biocompatibility. A particularly advantageous property of Mg is its natural biodegradation in vivo, …

In Vitro Comparative Study Of Composite Coatings For Magnesium-Based Bone Implants, Abdelrahman Amin, Bryce Williams, Thomas Mcgehee, Alyssandra Navarro, Vipul Patil, Mostafa Elsaadany, Hanna Ibrahim

Biomedical Engineering Faculty Publications and Presentations

This study provides a comparative assessment of the corrosion, morphology, and biological properties of four of the most promising coating methods for magnesium in biomedical applications, namely micro-arc oxidation (MAO), graphene oxide (GO)-containing MAO coating, MAO/sol-gel composite coating, and MAO/polycaprolactone (PCL) polymer dip coating approaches. Despite the abundance of research focused on these promising coating approaches, there is a notable lack of comparative studies evaluating their properties. To this end, the investigated composite coatings are ZK60+MAO, ZK60+MAO/GO, ZK60+MAO/Sol-gel, and ZK60+MAO/PCL composite coating. Several tests were used to assess various properties of the prepared groups such as in vitro corrosion characteristics, …

Loss Of Endogenous Circadian Clock Function In Mice Alters Respiratory Cycle Timing In A Time Of Day- And Sex-Specific Manner, Aaron A. Jones, Deanna M. Arble

Biological Sciences Faculty Research and Publications

Resting breathing and ventilatory chemoreflexes are regulated in a 24-hr manner by the endogenous circadian clock. However, it is unclear how circadian biology influences different phases of the breath-to-breath respiratory cycle which are predominantly controlled by pontomedullary regions of the brainstem. Here, we performed whole-body plethysmography during quiet wakefulness in young adult male and female mice lacking the core clock gene Brain and Muscle Arnt-like 1 (BMAL1) to determine the extent to which the molecular clock affects respiratory cycle timing and ventilatory airflow mechanics. Breath waveform analysis revealed that male BMAL1 knockout (KO) mice exhibit time of day-specific differences in …

Diabetes Potentiates The Emergence And Expansion Of Antibiotic Resistance, John C. Shook, Benjamin P. Darwitz, Kaleb J. Tyson, Amanda Z. Velez, Sophia K. Bridwell, Joshua B. Parsons, Sarah E. Rowe, Christopher Marshall, Brian P. Conlon, Lance R. Thurlow

Biological Sciences Faculty Research and Publications

Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. We examined how diabetes affects the emergence of antibiotic resistance in a Staphylococcus aureus SSTI. We determined that S. aureus evolves antibiotic resistance rapidly in diabetic mice, while resistance did not occur in nondiabetic mice over the course of infection. Diabetes-associated immune cell dysfunction plays a minor role in the emergence of resistance, while hyperglycemia plays a dominant role facilitating the expansion and takeover of resistant mutants in diabetic infections. Furthermore, vancomycin intermediate resistant isolates display a pronounced fitness defect in …

The Rad6-Like Ubiquitin Conjugase Gene Osubc7 Has A Positive Role In The Early Cold Stress Tolerance Response Of Rice, Huy Phan, Michael Schläppi

Biological Sciences Faculty Research and Publications

Background/Objectives: Cold stress poses a significant threat to Asian rice cultivation, disrupting important physiological processes crucial for seedling establishment and overall plant growth. It is, thus, crucial to elucidate genetic pathways involved in cold stress tolerance response mechanisms. Methods: We mapped OsUBC7, a Radiation-sensitive 6 (RAD6)-type homolog of rice, to a low-temperature seedling survivability (LTSS) QTL and used genomics, molecular genetics, and physiological assays to assess its role in plant resilience against low-temperature stress. Results: OsUBC7 is cold responsive and has higher expression levels in cold-tolerant japonica than cold-sensitive indica. Overexpression of OsUBC7 enhances LTSS of indica and freezing tolerance …

Editorial: Women In Antimicrobials, Resistance And Chemotherapy: 2023, Cindy Shuan Ju Teh, Krassimira R. Hristova, Ana R. Freitas

Biological Sciences Faculty Research and Publications

No abstract provided.

Evaluation Of The Accuracy Of The Niti K-Files And Gutta-Percha Cones In Gauging The Apical Foramen Using The Scanning Electron Microscope: An In Vitro Study, Marie-Louise Slim, Roula El Hachem, Lara Nasr, Romy Zouein, Rami Mhanna, Mia Karam, Issam Khalil

International Arab Journal of Dentistry

Objectives: The aim of this study was to compare the accuracy of apical gauging using NiTi K-files and gutta-percha cones and determine the level of agreement between the two methods using a Scanning Electron Microscope (SEM).

Methods: 75 circular and straight canals of mandibular first premolars were used. Canals were shaped using the R-Motion system (RM; FKG Dentaire, La Chaux-de-Fonds, Switzerland) and gauged using NiTi K-Files and gutta-percha cones matching the shaping instrument. Diameters measured on SEM images were used as the reference standard.

Results: There was a statistically significant difference in the prediction of apical diameter …

Accuracy And Reliability Of Anatomical Landmarks Compared Between 3d Facial Scanning And Cbct Radiographs: A Comparative Study, Mohamad Ahmad Munir Sakhita, Nayer Aboelsaad, Aly Osman

International Arab Journal of Dentistry

Introduction: Facial soft tissue evaluation is an important key for the overall patient diagnosis, treatment planning, and long-term prognoses. 3D patient imaging can be an alternative way to define the face providing the clinician with more accurate details, in comparison to the 2D imaging of soft tissues.

Objectives: The objective of this study was to evaluate the accuracy and reliability of anatomical landmarks comparing the 3D facial scanning with the CBCT radiographs.

Methods: The study was a comparative, crossover and descriptive study. Thirty patients (12 males and 18 females) with 15 to 30 years with a mean …

Continuous Monitoring Of Sterility: Bacterial Contamination And Disinfectant Performance In Dental Clinics, Nathaly Alsalloum, Tarek Aboajwa, Shuaib Alahmad, Nermin Almouhammad

International Arab Journal of Dentistry

Objectives: This study aimed to (1) evaluate contamination levels across three clinics (endodontic, extraction and surgery, and fixed prosthodontics), (2) identify the types and prevalence of bacteria, (3) estimate the effectiveness of a commercial disinfectant, and (4) determine the bacterial species most responsive to the disinfectant.

Methods: Equal surfaces (17.98 cm²) were swabbed, cultured on nutrient agar for the total aerobic microbial count before and after disinfection, and analyzed using settle plates. Bacterial identification was conducted through colony characteristics, Gram staining, and biochemical tests. Data were processed using SPSS version 26.

Results: The endodontic clinic exhibited …

Conservative Non-Surgical Endodontic Management Of A Large Cyst-Like Periapical Tunnel Lesion With 22-Month Cbct Follow-Up: A Case Report, Smriti Rohilla, Sameer Makkar, Sandeep Gupta

International Arab Journal of Dentistry

The present case report epitomises the successful non-surgical management of a large cyst-like periapical tunnel lesion of endodontic origin due to trauma using Lesion Sterilization and Tissue Repair technique. Endodontic orthograde treatment (and re-treatment) was performed in association with triple antibiotic paste as an intra-canal medication in a sixteen-year boy. Preoperative CBCT as well as at the 22 months CBCT followup were used to compare the evolution of the healing of the lesion. Accurate diagnosis in combination with non-surgical orthograde endodontic treatment can lead to can lead to complete healing of large lesions without any need of surgical intervention.

Symbols Of Sovereignty And How They Speak To Us: Reading Contemporary Wampum Artwork In New York State Museums, Marie Peterson

Electronic Theses & Dissertations (2024 - present)

Contemporary Haudenosaunee artworks in exhibit spaces across New York State are bringing cultural information and counter-historical narratives to the public that they might not encounter otherwise. Artwork that includes wampum depictions or materials has heuristic qualities that can engage viewers with Haudenosaunee ways of knowing and relating. Wampum heuristics and Haudenosaunee scholarship are employed to interrogate how wampum materials were collected, categorized, and researched by the New York State Museum during the salvage anthropology era. The narratives embedded in wampum artworks are traced from this salvage era history, throughout the century between the salvage era that began at the end …

“History Is Within And Around Us:” High School Students Actively Engage The Past In New York City, Alina Lewis

Electronic Theses & Dissertations (2024 - present)

Background/Context: Research on history education in the United States context has focused narrowly on history as a cognitive practice. This body of research assumes that it is difficult for students to “think like historians” (Wineburg, 1999) and is largely focused on advancing a discrete set of historical thinking skills through curricular interventions. Largely ignored in this discourse are the ways in which students engage with the past in out-of-school contexts.

Purpose/Objective: This study examines students’ engagements with history in out-of-school contexts. It is my hope that better understanding and describing how students experience history outside of school spaces will suggest …

Adaptive Evolution Shapes The Transmissibility Of West Nile Virus In New York State, Sean M. Bialosuknia

Electronic Theses & Dissertations (2024 - present)

Arthropod-borne viruses (arboviruses), which are maintained in nature in complex transmission cycles involving hematophagic invertebrates and their vertebrate hosts, are the cause of a significant and expanding global health burden. Defining arbovirus-host interactions is necessary if we are to understand the adaptive and epidemiological potential of arboviruses. The results presented with West Nile virus (WNV Flaviviridae: Orthoflavivirus), are a compilation of such studies. WNV is the most prevalent arboviral pathogen in the U.S. and the most geographically distributed arbovirus in the world. Despite the evolutionary potential of these RNA viruses, WNV and other arboviruses have experienced only limited …

Socio-Economic And Infrastructural Determinants Of Response Time Disparities Across Emergency Service Agencies, Alice N. Ottah

Electronic Theses & Dissertations (2024 - present)

This study comprehensively analyzes the determinants of disparities in emergency response times for EMS, Fire, and Police agencies in San Francisco from 2021 to 2023, utilizing a multilevel modeling framework and publicly accessible data. Contrary to a primary reliance on structural neighborhood factors, this research reveals that while neighborhood disadvantage statistically significantly interacts with agency type to influence response times, its direct effect is weak and not uniformly consistent across services. Specifically, the analysis demonstrates that variance in call response times across neighborhoods is minimal (Intraclass Correlation Coefficients < 0.02), the effects of disadvantage are agency-specific (null effects for Police and Fire), and even when significant (for EMS calls only), response times are faster in more disadvantaged neighborhoods. These findings challenge the existing literature on emergency response times and highlight the need for tailored policy interventions that consider both neighborhood context and agency-specific operations to promote equitable emergency response.

Musical Motivation: Investigating Musical Contingent Self-Worth And Its Interactions With Music Training And Perceived Musical Ability, Douglas Allan Kowalewski

Electronic Theses & Dissertations (2024 - present)

This program of research centers on a novel measure of how much value one places on having and displaying their musical ability – musical contingent self-worth – and how that construct interacts with existing measures of music training and perceived musical ability to predict performance on both musical and general cognitive tasks. Two studies (Experiments 1 and 2) provide evidence for the validity and reliability of an MCSW scale and additionally show that it uniquely predicts both reactions to, and performance on, a musical skills task (Experiment 1). These initial studies also show that MCSW interacts with music training to …

Framing Ethnicity: How Ideological Threats Shape State Policies Towards The Ethnic Chinese In Southeast Asia, Zheng Wang

Electronic Theses & Dissertations (2024 - present)

Post-colonial multiethnic societies still face significant challenges in nation-building today. Not only do countries follow different paths in dealing with ethnic diversity, but many also shift their strategies across time. State policies towards the ethnic Chinese in Southeast Asia, including accommodation, integration, marginalization, and assimilation, vary along two dimensions: the state’s discrimination towards the ethnic Chinese and the room for negotiation between the state and the ethnic Chinese in formulating these policies. Based on puzzling empirical observations on differing levels of changes in state policies towards the ethnic Chinese in Indonesia, Malaysia, and Singapore in the 1960s and 1970s, my …

School Contexts And The Construction Of Literacy Practices And Identities Among Middle School Students Of Color, Eugene K. Gyekye

Electronic Theses & Dissertations (2024 - present)

This dissertation investigates how middle school students of color construct and negotiate their literacy identities within an urban public school's institutional, classroom, and online contexts. The study is situated at Oakville Middle School, a culturally and linguistically diverse setting that reflects the complexities of adolescent literacy education in contemporary urban environments. The research explores how students' literacy practices are shaped by their interactions with school structures, pedagogical approaches, peer dynamics, and digital platforms and how these experiences influence their development as literate individuals.

The study responds to the persistent challenge of educational inequity, particularly the disconnect between students' cultural identities …

Waveforms For Next Generation Non-Stationary Channels, Zhibin Zou

Electronic Theses & Dissertations (2024 - present)

Waveform design aims to achieve orthogonality among data signals/symbols across all available Degrees of Freedom (DoF) to avoid interference while transmitted over the channel. Precoding involves the decomposition of the channel matrix into orthogonal components for the purpose of constructing a precoding matrix that is then combined with the data signal to achieve orthogonality in the spatial dimension. On the other hand, modulation uses orthogonal carriers in a certain signal space to carry data symbols with minimal interference from other symbols. However, it is widely evident that next Generation (xG) wireless systems will experience very high mobility, density and time-varying …

Walk The Talk? Public Libraries And Organizational Responsiveness To Marginalized Communities, Soohyun Park

Electronic Theses & Dissertations (2024 - present)

Public libraries are public service organizations, playing a critical role in ensuring equitable access to education and information for the community. Despite their growing importance, there is limited empirical evidence on how local libraries respond to the needs of diverse socioeconomic populations within their communities. This study examines the collection management decisions of local public libraries to assess whether they make differentiated service decisions and what factors influence their responsiveness. Using the concept of organizational responsiveness, it explores organizational responsiveness through the lens of equitable distribution of public service benefits and considers the role of public administrators in shaping those …

Contributions Of Birthing People’S Prenatal Parasympathetic Nervous System Functioning And Postnatal Sensitivity On Infant Temperament, Amanda M. Flagg

Electronic Theses & Dissertations (2024 - present)

Grounded in developmental psychobiology, this research aimed to elucidate how birthing people’s physiological regulation during pregnancy may shape the early emergence of socioemotional development in early infancy. The present study examined how birthing people’s prenatal parasympathetic nervous system (PNS) activity, specifically baseline high-frequency heart rate variability (HF-HRV) and HF-HRV withdrawal, and postnatal sensitivity contributes to infant temperamental reactivity at six months of age. The study aimed to clarify early developmental mechanisms through which birthing people’s PNS shapes emerging infant temperament. Data were drawn from a longitudinal cohort of Black and African American birthing people, a population underrepresented in psychophysiological research, …

Betti Numbers Of Generic Ideals, Jason R. Howell

Electronic Theses & Dissertations (2024 - present)

We present results related to Betti numbers of so called generic ideals over a polynomial ring $T = \Bbbk[x_1, \ldots, x_n]$. For each $m$ define $T(m) = T/(x_{m+1}, \ldots, x_n)$ and for a homogeneous ideal $J$ we use the notation $J(m) = JT(m)$. Also we set $Q(m) = T(m)/J(m)$, and $L(m) = ann_{Q(m)}(x_m)$. The first main result is Theorem \ref{Long Exact Sequence} where we produce the following long exact sequence \begin{align*} \cdots \rightarrow &Tor_{k+1,j}^{T(m-1)}(Q(m-1),\Bbbk) \rightarrow Tor_{k-1,j+1}^{T(m-1)}(L(m),\Bbbk)_{j-1} \rightarrow Tor_{k,j}^{T(m)}(Q(m),\Bbbk) \rightarrow \\ &Tor_{k,j}^{T(m-1)}(Q(m-1),\Bbbk) \rightarrow Tor_{k-2,j-1}^{T(m-1)}(L(m),\Bbbk) \rightarrow \cdots. \end{align*} The second main result is Theorem \ref{Theorem F(j,m) equiv k(j,m)} where we explicitly describe …

Interactions Between Lipopolysaccharide And Capsule Retention In Klebsiella Pneumoniae And The Resultant Effects On Macrophages, Juliane Leigh Nguy

UNF Graduate Theses and Dissertations

Klebsiella pneumoniae is the third most common cause of nosocomial infections in the United States. The capsular polysaccharides (CPS) are virulence factors allowing K. pneumoniae to evade host immune systems. The current model of capsule structure indicates that CPS fibrils interact with the external O-antigen of lipopolysaccharide molecules to enhance retention to the bacterial outer membrane. These interactions may influence pathogenicity in clinically relevant strains. This study characterized alterations to LPS and CPS structure, the impact of these changes on capsule retention, membrane permeability, biofilm formation, and macrophage interactions. LPS and CPS were quantified and visualized in four strains of …