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2025

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Examining Effects Of A Cultural And Family Resilience Program On Improving Physical Activity And Eating Behaviors Among Overweight Black Adolescents, Mary Quattlebaum Jan 2025

Examining Effects Of A Cultural And Family Resilience Program On Improving Physical Activity And Eating Behaviors Among Overweight Black Adolescents, Mary Quattlebaum

Theses and Dissertations

Black adolescents have higher rates of physical inactivity, lower quality dietary intake, and fewer family meals compared to their White peers. These health inequities place Black adolescents at greater risk for overweight and obesity, as well as long-term health consequences, including chronic disease and early mortality. However, few health promotion programs have been successful in improving health behaviors among Black adolescents and families. Elevated rates of chronic stress, namely racial stress, among Black families may be a prominent obstacle for engagement in and effectiveness of health promotion initiatives. Limited family-based health promotion programs with Black families have incorporated cultural and …


Choice Overload In The Digital Age: A Cognitive Neuroscience Approach, Jacob Matthew Stanley Jan 2025

Choice Overload In The Digital Age: A Cognitive Neuroscience Approach, Jacob Matthew Stanley

Theses and Dissertations

This dissertation examines the neural mechanisms of value-based multiattribute decision making through the lens of choice overload during consumer choice. Two behavioral experiments established that choice sets of a moderate size with nine options were perceived as most optimal compared to choice sets with three and 24 options, and options chosen from the largest set size were judged to be the least satisfying. A functional MRI study then examined how the brain responds to choice sets varying in size and complexity by manipulating the number of options presented as well as the presence of asymmetrically dominated decoy alternatives during a …


Delayed Excretion Of High-Dose Methotrexate In Pediatric Acute Leukemia Correlates With Laxative And Constipation Management, Jennifer A Belsky, Ashley Chavana, Ankona Banerjee, Mark Zobeck, Eric S Schafer, Karen R Rabin, Monica Gramatges, Alex Sim, Audrey Leisinger, Trisha Reddy, Megan J Parod, Philip Lupo, Michael Scheurer, Austin L Brown, M Brooke Bernhardt Jan 2025

Delayed Excretion Of High-Dose Methotrexate In Pediatric Acute Leukemia Correlates With Laxative And Constipation Management, Jennifer A Belsky, Ashley Chavana, Ankona Banerjee, Mark Zobeck, Eric S Schafer, Karen R Rabin, Monica Gramatges, Alex Sim, Audrey Leisinger, Trisha Reddy, Megan J Parod, Philip Lupo, Michael Scheurer, Austin L Brown, M Brooke Bernhardt

Faculty, Staff and Students Publications

Background: Delayed excretion of high-dose methotrexate (HD-MTX) in pediatric acute lymphoblastic leukemia (ALL) can result in significant morbidity. While methotrexate is primarily renally excreted, HD-MTX may overwhelm renal excretion and increase reliance on fecal elimination. This study evaluated the association between laxative use for constipation and delayed excretion of HD-MTX.

Methods: This multisite chart review included pediatric patients with ALL (2010-2020) who received HD-MTX (5 g/m2). Delayed excretion was defined as a serum MTX concentration greater than 0.4 µM at Hour 48. We identified use of laxative medications after each HD-MTX infusion, with receipt of two or more doses considered …


Voice-Activated Self-Monitoring Application (Vois): User Acceptance And Satisfaction In The Field, Hyunkyoung Oh, Li Yang, Tala Abu Zahra, Shiyu Tian, Min Sook Park, Jake Luo, Sheikh Iqbal Ahamed, Evelyn Chan, Jeffrey Whittle Jan 2025

Voice-Activated Self-Monitoring Application (Vois): User Acceptance And Satisfaction In The Field, Hyunkyoung Oh, Li Yang, Tala Abu Zahra, Shiyu Tian, Min Sook Park, Jake Luo, Sheikh Iqbal Ahamed, Evelyn Chan, Jeffrey Whittle

Computer Science Faculty Research and Publications

This paper illustrates the processes and results of user acceptance and satisfaction tests for the voice-activated self-monitoring (VoiS) application conducted in the field. VoiS was designed and developed for individuals with diabetes (DM) and hypertension (HTN) to support their routine and convenient self-management using a smart speaker platform. VoiS is also accessible on users’ mobile devices to visualize user-generated data. A total of nine adults with DM and HTN participated and were asked to use the VoiS system at home for a week to identify its acceptability in real-world conditions. Participants completed phone interviews to report operational errors and a …


Bayesian Covariate-Dependent Circadian Modeling Of Rest-Activity Rhythms, Beniamino Hadj-Amar, Vaishnav Krishnan, Marina Vannucci Jan 2025

Bayesian Covariate-Dependent Circadian Modeling Of Rest-Activity Rhythms, Beniamino Hadj-Amar, Vaishnav Krishnan, Marina Vannucci

Faculty, Staff and Students Publications

We propose a Bayesian covariate-dependent anti-logistic circadian model for analyzing activity data collected via wrist-worn wearable devices. The proposed approach integrates covariates into the modeling of the amplitude and phase parameters, facilitating cohort-level analysis with enhanced flexibility and interpretability. To promote model sparsity, we employ an l1-ball projection prior, enabling precise control over complexity while identifying significant predictors. We assess performances on simulated data and then apply the method to real-world actigraphy data from people with epilepsy. Our results demonstrate the model’s effectiveness in uncovering complex relationships among demographic, psychological, and medical factors influencing rest-activity rhythms, offering insights for …


Epilepsy Clinic Analytics: Leveraging Emr Reporting Tools To Characterize Center Volume And Complexity, Vanuli Arya, Arindam Ghosh Mazumder, Muna Nnamani, Mark A Abboud, Samuel C Lee, Michael S Guzman, Vaishnav Krishnan Jan 2025

Epilepsy Clinic Analytics: Leveraging Emr Reporting Tools To Characterize Center Volume And Complexity, Vanuli Arya, Arindam Ghosh Mazumder, Muna Nnamani, Mark A Abboud, Samuel C Lee, Michael S Guzman, Vaishnav Krishnan

Faculty, Staff and Students Publications

Introduction: Epilepsy centers connect patients to multidisciplinary provider groups that can coordinate surgical interventions and/or investigational treatments. Automated techniques to cross-sectionally review patient volume and complexity may reveal objective metrics to assign appropriate personnel and resources. Here, we leveraged an electronic medical record (EMR) reporting tool to examine how patient and visit volumes, antiseizure medication (ASM) prescriptions and neuromodulation use evolved over an 11-year epoch at a single level 4 adult epilepsy center in Texas, USA.

Methods: Using Epic Workbench Reporting, we acquired the dates of (i) all clinic visits (office or telemedicine), (ii) CPT codes for neuromodulation interrogation/programming, and …


Relationships Of Personality Traits With The Taxonomic Composition Of The Gut Microbiome Among Psychiatric Inpatients, William Orme, Sandra L Grimm, Divya S N Vella, J Christopher Fowler, B Christopher Frueh, Benjamin L Weinstein, Joseph Petrosino, Cristian Coarfa, Alok Madan Jan 2025

Relationships Of Personality Traits With The Taxonomic Composition Of The Gut Microbiome Among Psychiatric Inpatients, William Orme, Sandra L Grimm, Divya S N Vella, J Christopher Fowler, B Christopher Frueh, Benjamin L Weinstein, Joseph Petrosino, Cristian Coarfa, Alok Madan

Faculty, Staff and Students Publications

Objective: Through the brain-gut-microbiome axis, myriad psychological functions that affect behavior share a dynamic, bidirectional relationship with the intestinal microbiome. Little is known about the relationship between personality-a stable construct that influences social- and health-related behaviors-and the bacterial ecosystem. The authors of this exploratory study examined the relationship between general and maladaptive personality traits and the composition of the gut microbiome.

Methods: In total, 105 psychiatric inpatients provided clinical data and fecal samples. Personality traits were measured with the five-factor model of personality, the Structured Clinical Interview for DSM-IV Axis II Personality Disorders, and the Personality Inventory for DSM-5; 16S …


Poststroke Impulsivity: A Narrative Review, Melissa B Jones, Dakota E Broadway, Malena Gimenez-Zapiola, Ricardo E Jorge Jan 2025

Poststroke Impulsivity: A Narrative Review, Melissa B Jones, Dakota E Broadway, Malena Gimenez-Zapiola, Ricardo E Jorge

Faculty, Staff and Students Publications

In this narrative review, the authors examine the multidimensional nature and presentations of impulsivity after stroke. Impulsivity manifests as immediate or premature responses, impaired delayed gratification, perseverance despite punishment, and other displays of impaired emotional and behavioral regulation. The literature on the assessments, outcomes, and treatment of patients with these various manifestations after a cerebrovascular injury is reviewed. Findings from case reports indicate that poststroke impulsivity may manifest across neurobehavioral syndromes that are not well defined in the psychiatric nomenclature, such as alien hand syndrome and atypical impulse control disorders. Overall, impulse control disorders appear to be rare poststroke. Therapeutic …


Towards A Common Approach For Managing Food Allergy And Serious Allergic Reactions (Anaphylaxis) At School. Ga2len And Efa Consensus Statement, Antoine Deschildre, Montserrat Alvaro-Lozano, Antonella Muraro, Marcia Podesta, Debra De Silva, Mattia Giovannini, Simona Barni, Timothy E Dribin, Mónica Sandoval-Ruballos, Aikaterini Anagnostou, Alessandro Fiocchi, Alice Toniolo, Andrew Bird, Angel Sánchez Sanz, Anna Asarnoj, Anna Nowak-Wegrzyn, Berber Vlieg-Boerstra, Brian P Vickery, Carina Venter, Caroline Nilsson, Cecilia Parente, Céline Demoulin, David M Fleischer, Diola Bijlhout, Edward F Knol, Eleanor Garrow, Emma E Cook, Fallon Schultz, Francesca Lazzarotto, Francesca Mori, Gary Wong, Gideon Lack, Graham Roberts, Gustavo Andres Marino, H N G Oude Elberink, Helen A Brough, Hugh A Sampson, Jay Lieberman, Jennifer Gerdts, Jing Zhao, Josefine Gradman, Julia E M Upton, Julie Wang, Kati Palosuo, Kirsi M Järvinen, Kirsten Beyer, Kunling Shen, Laura Polloni, Lianne Mandelbaum, Luciana Kase Tanno, Lucy A Bilaver, Marcus S Shaker, Margitta Worm, Maria Said, Mary Kelly, Mary Jane Marchisotto, Michael Makris, Mikaela Odemyr, Montserrat Fernandez-Rivas, Motohiro Ebisawa, Nandinee Patel, Pablo Rodríguez Del Río, Pakit Vichyanond, Paul Turner, Pete Smith, Pilar Morón Gaspar, R Sharon Chinthrajah, Rima Rachid, Roberta Bonaguro, Ruchi Gupta, Sabine Schnadt, Sakura Sato, Stefania Arasi, Stephanie Leonard, Sung Poblete, Susanne Halken, Thuy-My Le, Guillaume Pouessel, Tracey Dunn, Victoria Cardona, Torsten Zuberbier Jan 2025

Towards A Common Approach For Managing Food Allergy And Serious Allergic Reactions (Anaphylaxis) At School. Ga2len And Efa Consensus Statement, Antoine Deschildre, Montserrat Alvaro-Lozano, Antonella Muraro, Marcia Podesta, Debra De Silva, Mattia Giovannini, Simona Barni, Timothy E Dribin, Mónica Sandoval-Ruballos, Aikaterini Anagnostou, Alessandro Fiocchi, Alice Toniolo, Andrew Bird, Angel Sánchez Sanz, Anna Asarnoj, Anna Nowak-Wegrzyn, Berber Vlieg-Boerstra, Brian P Vickery, Carina Venter, Caroline Nilsson, Cecilia Parente, Céline Demoulin, David M Fleischer, Diola Bijlhout, Edward F Knol, Eleanor Garrow, Emma E Cook, Fallon Schultz, Francesca Lazzarotto, Francesca Mori, Gary Wong, Gideon Lack, Graham Roberts, Gustavo Andres Marino, H N G Oude Elberink, Helen A Brough, Hugh A Sampson, Jay Lieberman, Jennifer Gerdts, Jing Zhao, Josefine Gradman, Julia E M Upton, Julie Wang, Kati Palosuo, Kirsi M Järvinen, Kirsten Beyer, Kunling Shen, Laura Polloni, Lianne Mandelbaum, Luciana Kase Tanno, Lucy A Bilaver, Marcus S Shaker, Margitta Worm, Maria Said, Mary Kelly, Mary Jane Marchisotto, Michael Makris, Mikaela Odemyr, Montserrat Fernandez-Rivas, Motohiro Ebisawa, Nandinee Patel, Pablo Rodríguez Del Río, Pakit Vichyanond, Paul Turner, Pete Smith, Pilar Morón Gaspar, R Sharon Chinthrajah, Rima Rachid, Roberta Bonaguro, Ruchi Gupta, Sabine Schnadt, Sakura Sato, Stefania Arasi, Stephanie Leonard, Sung Poblete, Susanne Halken, Thuy-My Le, Guillaume Pouessel, Tracey Dunn, Victoria Cardona, Torsten Zuberbier

Faculty, Staff and Students Publications

GA2LEN and EFA propose minimum specifications for all industrialised countries/regions to work towards to support students with food allergies in educational settings. We reviewed research and legislation and gained feedback from over 100 patient and professional groups. We built shared expectations around: 1. training all school staff about what food allergy is, the symptoms of allergic reactions, what to do in an emergency, and when and how to use and store devices that laypeople can use to administer adrenaline (epinephrine). 2. preventing allergic reactions by using clear labelling on school menus and prepacked and non‐prepacked foods and regular cleaning where …


Plasma Protein-Based And Polygenic Risk Scores Serve Complementary Roles In Predicting Inflammatory Bowel Disease, Jakob Woerner, Thomas Westbrook, Seokho Jeong, Manu Shivakumar, Allison R Greenplate, Sokratis A Apostolidis, Seunggeun Lee, Yonghyun Nam, Dokyoon Kim Jan 2025

Plasma Protein-Based And Polygenic Risk Scores Serve Complementary Roles In Predicting Inflammatory Bowel Disease, Jakob Woerner, Thomas Westbrook, Seokho Jeong, Manu Shivakumar, Allison R Greenplate, Sokratis A Apostolidis, Seunggeun Lee, Yonghyun Nam, Dokyoon Kim

Faculty, Staff and Students Publications

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), has a significant genetic component and is increasingly prevalent due to environmental factors. Current polygenic risk scores (PRS) have limited predictive power and cannot inform time of symptom onset. Circulating proteomics profiling offers a novel, non-invasive approach for understanding the inflammatory state of complex diseases, enabling the creation of proteomic risk scores (ProRS). This study utilizes data from 51,772 individuals in the UK Biobank to evaluate the unique and combined contributions of PRS and ProRS to IBD risk prediction. We developed ProRS models for CD and UC, assessed …


Integrated Multi-Omics Analyses Of Synaptosomes Revealed Synapse-Associated Novel Targets In Alzheimer’S Disease, Subodh Kumar, Enrique Ramos, Axel Hidalgo, Daniela Rodarte, Bhupender Sharma, Melissa M. Torres, Davin Devara, Shrikanth Gadad Jan 2025

Integrated Multi-Omics Analyses Of Synaptosomes Revealed Synapse-Associated Novel Targets In Alzheimer’S Disease, Subodh Kumar, Enrique Ramos, Axel Hidalgo, Daniela Rodarte, Bhupender Sharma, Melissa M. Torres, Davin Devara, Shrikanth Gadad

School of Medicine Publications

Synapse dysfunction is an early event in Alzheimer’s disease (AD) caused by various factors, including amyloid beta, p-tau, inflammation, and aging. However, the precise molecular mechanism underlying synapse dysfunction in AD remains largely unknown. To understand this, we comprehensively analyzed the synaptosomes fraction in post-mortem brain samples from AD patients and cognitively normal individuals. We conducted high-throughput transcriptomic analyses to identify changes in microRNA (miRNA) and mRNA levels in synaptosomes extracted from the brains of unaffected individuals and those with AD. Additionally, we performed mass spectrometry analysis of synaptosomal proteins in the same sample group. These analyses revealed significant differences …


Infants’ Resting-State Functional Connectivity And Event-Related Potentials: A Multimodal Approach To Investigating The Neural Basis Of Infant Novelty Detection, Dana Kanel, Santiago Morales, Kathryn Altman, John E. Richards, Anderson M. Winkler, Daniel Samuel Pine, Nathan A. Fox, Courtney A. Filippi Jan 2025

Infants’ Resting-State Functional Connectivity And Event-Related Potentials: A Multimodal Approach To Investigating The Neural Basis Of Infant Novelty Detection, Dana Kanel, Santiago Morales, Kathryn Altman, John E. Richards, Anderson M. Winkler, Daniel Samuel Pine, Nathan A. Fox, Courtney A. Filippi

School of Medicine Publications

Individual differences in how the brain responds to novelty are present from infancy. A common method of studying novelty processing is through event-related potentials (ERPs). While ERPs possess millisecond precision, spatial resolution remains poor, especially in infancy. This study aimed to balance spatial and temporal precision by combining ERP data with functional magnetic resonance imaging (fMRI) data. Twenty-nine infants (15 female) underwent resting-state fMRI (Mage = 4.73 months) and electroencephalography (EEG) during a three-stimulus auditory oddball task (Mage = 5.19 months). The mismatch response (MMR) and P3 were computed from ERP data, and resting-state functional connectivity …


Affective Bias Predicts Changes In Depression During Deep Brain Stimulation Therapy, Brian Cui, Madaline M Mocchi, Brian A Metzger, Prathik Kalva, John F Magnotti, Jess G Fiedorowicz, Allison Waters, Christopher K Kovach, Yvonne Y Reed, Raissa K Mathura, Camille Steger, Bailey Pascuzzi, Kourtney Kanja, Ashan Veerakumar, Vineet Tiruvadi, Andrea Crowell, Lydia Denison, Christopher J Rozell, Nader Pouratian, Wayne Goodman, Patricio Riva Posse, Helen S Mayberg, Kelly Rowe Bijanki Jan 2025

Affective Bias Predicts Changes In Depression During Deep Brain Stimulation Therapy, Brian Cui, Madaline M Mocchi, Brian A Metzger, Prathik Kalva, John F Magnotti, Jess G Fiedorowicz, Allison Waters, Christopher K Kovach, Yvonne Y Reed, Raissa K Mathura, Camille Steger, Bailey Pascuzzi, Kourtney Kanja, Ashan Veerakumar, Vineet Tiruvadi, Andrea Crowell, Lydia Denison, Christopher J Rozell, Nader Pouratian, Wayne Goodman, Patricio Riva Posse, Helen S Mayberg, Kelly Rowe Bijanki

Faculty, Staff and Students Publications

Introduction: Deep brain stimulation (DBS) is a promising treatment for refractory depression, utilizing surgically implanted electrodes to stimulate specific anatomical targets within the brain. However, limitations of patient-reported and clinician-administered mood assessments pose obstacles in evaluating DBS treatment efficacy. In this study, we investigated whether an affective bias task, which leverages the inherent negative interpretation bias seen in individuals with depression, could serve as a reliable measure of mood changes during DBS therapy in patients with treatment-resistant depression.

Methods: Two cohorts of patients (n = 8, n = 2) undergoing DBS for treatment-resistant depression at different academic medical centers …


Diagnostic And Prognostic Value Of Cystatin C In Acute Coronary Syndrome: An Up-To-Date Meta-Analysis, Michal Pruc, Damian Swieczkowski, Basar Cander, Milosz J Jaguszewski, Sagar Galwankar, Salvatore Di Somma, Fatimah Lateef, Indrani Sardesai, Ayman El-Menyar, Michal Zembala, Jacek Kubica, Togay Evrin, Burak Katipoglu, Zubaid Rafique, Frank William Peacock, Lukasz Szarpak Jan 2025

Diagnostic And Prognostic Value Of Cystatin C In Acute Coronary Syndrome: An Up-To-Date Meta-Analysis, Michal Pruc, Damian Swieczkowski, Basar Cander, Milosz J Jaguszewski, Sagar Galwankar, Salvatore Di Somma, Fatimah Lateef, Indrani Sardesai, Ayman El-Menyar, Michal Zembala, Jacek Kubica, Togay Evrin, Burak Katipoglu, Zubaid Rafique, Frank William Peacock, Lukasz Szarpak

Faculty, Staff and Students Publications

Background: The role of Cystatin C (CysC) in the diagnosis and prognosis of cardiovascular disease, particularly acute coronary syndrome (ACS), is increasingly significant. The goal of this meta-analysis was to assess the diagnostic and prognostic value of CysC in patients with ACS, as well as its association with major adverse cardiovascular events (MACE), defined as mortality, myocardial infarction, heart failure, and stroke.

Methods: The present study is a systematic review and meta-analysis. Using PubMed, Web of Science, Cochrane Library, and Embase, a literature review of cohort and case control studies reporting MACE and using the terms ACS and Cystatin C …


Examining Parents’ Perceptions Of Their Children’S Autism And Completion Of Genetic Testing, Georgina J Sakyi, Sarah S Mire, Robin P Goin-Kochel, Chaya N Murali, Susan X Day Jan 2025

Examining Parents’ Perceptions Of Their Children’S Autism And Completion Of Genetic Testing, Georgina J Sakyi, Sarah S Mire, Robin P Goin-Kochel, Chaya N Murali, Susan X Day

Faculty, Staff and Students Publications

Though genetic testing is recommended for children diagnosed with autism spectrum disorder (ASD), both internal (e.g. parents’ and providers’ valuation of genetic testing) and external (e.g. insurance coverage) barriers exist, and exploration of these factors is required to close the gap between provider recommendations and parent follow-through. In a sample of 290 parents, we explored (a) how parents’ ASD-related etiological beliefs and symptom attributions, as well as income, affected genetic testing completion; and (b) whether these factors influence parents’ hopes or concerns about genetic testing. Principal component analysis (PCA) was used to investigate the factor structure of the ASD attribution …


“The Culture - I Wish It Were Less Intense And More Joyful And Full Of Life”: A Youth Participatory Action Study On Teen Mental Health And Wellness, Marna Wolak Jan 2025

“The Culture - I Wish It Were Less Intense And More Joyful And Full Of Life”: A Youth Participatory Action Study On Teen Mental Health And Wellness, Marna Wolak

Doctoral Dissertations

Studies indicate that a grave mental health crisis is disproportionately impacting female-identified youth. While school districts have made attempts to address this problem, those most impacted - young people - have frequently found their voices overlooked by adults seeking solutions. Therefore, this Youth Participatory Action Research (YPAR) study, grounded in humanizing and liberatory pedagogy, examines how high school-aged students in an urban school district understand and define their experiences with mental health challenges and suggest strategies and interventions for improved wellness. Two sets of research questions guide this study: 1) Primary questions: What are youth perspectives about how their mental …


Tb And Diabetes In Eswatini: Addressing Suboptimal Treatment Outcomes Through Integrated Services, Yael Hirsch-Moverman, Dana Bezuidenhout, Sakthi Senthilvelan, Lobsang Palmo, Debrah Vambe, Ntombifuthi Ginindza, Nonhlanhla Dlamini, Andrea A Howard, Joanne E Mantell Jan 2025

Tb And Diabetes In Eswatini: Addressing Suboptimal Treatment Outcomes Through Integrated Services, Yael Hirsch-Moverman, Dana Bezuidenhout, Sakthi Senthilvelan, Lobsang Palmo, Debrah Vambe, Ntombifuthi Ginindza, Nonhlanhla Dlamini, Andrea A Howard, Joanne E Mantell

Faculty, Staff and Students Publications

Tuberculosis (TB) remains a significant public health challenge in Eswatini, a country with the highest global HIV prevalence. Diabetes mellitus (DM) is increasingly common among people newly diagnosed with TB, contributing to suboptimal TB treatment outcomes, including relapse and death. The DETECT study employed a multi-method approach to assess the prevalence and DM impact on TB treatment outcomes among adults with TB in 10 Ministry of Health facilities in Eswatini, and explore barriers and facilitators to integrating TB/DM services. DM screening was conducted using laboratory-based glycated hemoglobin (A1c) testing, with DM defined as A1c ≥ 6.5% and preDM as A1c …


An Innovative Approach To Assessing The Psychosocial Impacts On Liver Transplant Recipients: The Prediction-By-Correspondence Analysis, Se-Kang Kim, Rachel A Annunziato Jan 2025

An Innovative Approach To Assessing The Psychosocial Impacts On Liver Transplant Recipients: The Prediction-By-Correspondence Analysis, Se-Kang Kim, Rachel A Annunziato

Faculty, Staff and Students Publications

Background: Innovative analytic techniques are applied to the psychological functioning of liver transplant (LT) recipients to comprehend its effect on post-transplant survival, hypothesizing that adherence will be predicted by psychosocial functioning.

Methods: The psychosocial functioning of 248 LT recipients (88 females) aged 19 to 74 is assessed using the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT). In addition, the Medication Level Variability Index (MLVI) and biopsy-proven rejection are utilized to evaluate successful adherence. The Z-scores of the SIPAT scores are used to transform them into an ordinal variable with excellent, good, minimally acceptable, and poor categories. We employ a modified …


Multidisciplinary Approach To Treating Complex Immune Dysregulation Disorders: An Adaptive Model For Institutional Implementation, Lauren A Henderson, Roshini S Abraham, Aisha Ahmed, Lindsey Blount, Scott W Canna, Natalia S Chaimowitz, Shanmuganathan Chandrakasan, Bria Coates, James A Connelly, Megan A Cooper, Christine N Duncan, Anthony French, Melissa Hazen, Michelle L Hermiston, Brian Nolan, Anish Ray, Melissa J Rose, Lisa Forbes Satter, Grant Schulert, Sara Kristen Sexson Tejtel, Tiphanie Vogel, Kelly Walkovich, Matt S Zinter, Edward M Behrens Jan 2025

Multidisciplinary Approach To Treating Complex Immune Dysregulation Disorders: An Adaptive Model For Institutional Implementation, Lauren A Henderson, Roshini S Abraham, Aisha Ahmed, Lindsey Blount, Scott W Canna, Natalia S Chaimowitz, Shanmuganathan Chandrakasan, Bria Coates, James A Connelly, Megan A Cooper, Christine N Duncan, Anthony French, Melissa Hazen, Michelle L Hermiston, Brian Nolan, Anish Ray, Melissa J Rose, Lisa Forbes Satter, Grant Schulert, Sara Kristen Sexson Tejtel, Tiphanie Vogel, Kelly Walkovich, Matt S Zinter, Edward M Behrens

Faculty, Staff and Students Publications

Patients with immune dysregulation may present with varying combinations of autoimmunity, autoinflammation, immunodeficiency, atopy, lymphoproliferation, and/or malignancy, often with multisystem involvement. Recognizing specific patterns of immune dysregulation, coordinating and interpreting complex diagnostic testing, and choosing initial (often empiric) treatment can be challenging. Centers are increasingly assembling multidisciplinary teams (MDTs) to standardize evaluation and optimize treatment of patients with complex immune dysregulation (immune dysregulation MDTs [immMDTs]). However, published information on the composition and function of immMDTs is sparse, and there is little guidance for those seeking to establish or optimize an immMDT. To inform this review, we assembled a panel of …


Healthcare Utilization Unchanged In The Control Arm Of A Randomized Clinical Trial, Pratik Gongloor, Saad Nadeem, Xiaoying Yu, Mukaila Raji, Kristina D Mena, Elizabeth M Vaughan Jan 2025

Healthcare Utilization Unchanged In The Control Arm Of A Randomized Clinical Trial, Pratik Gongloor, Saad Nadeem, Xiaoying Yu, Mukaila Raji, Kristina D Mena, Elizabeth M Vaughan

Faculty, Staff and Students Publications

including among control groups. Increased access to care and heightened health awareness during trial enrollment could lead to altered behaviors, a phenomenon known as the Hawthorne effect, which may obscure true intervention impacts; however, this effect remains poorly studied in low-income environments.

Aim: To conduct a secondary exploratory analysis of healthcare utilization among control participants of a randomized clinical trial (RCT).

Methods: We retrospectively analyzed electronic medical records from the control arm (n = 26) of an RCT involving low-income Hispanic adults with type 2 diabetes receiving care at a community clinic. Before randomization to a 12-month diabetes education intervention …


Strategies For The Secondary Prevention Of Atherosclerotic Cardiovascular Disease, Madelyn Hurwitz, Olayinka J Agboola, Abhishek Gami, Marlene S Williams, Salim S Virani, Garima V Sharma, Jaideep Patel Jan 2025

Strategies For The Secondary Prevention Of Atherosclerotic Cardiovascular Disease, Madelyn Hurwitz, Olayinka J Agboola, Abhishek Gami, Marlene S Williams, Salim S Virani, Garima V Sharma, Jaideep Patel

Faculty, Staff and Students Publications

Patients with atherosclerotic cardiovascular disease (ASCVD), such as those with a history of MI or stroke, are at high risk for morbidity and mortality associated with future cardiovascular events. Ideal management of these patients requires a multifactorial strategy for risk factor mitigation and prevention of additional cardiovascular events. Traditional management of secondary prevention patients involves lipid-lowering with statins, blood pressure control, and anti-platelet treatment. Several additional targets have been identified to optimize the secondary prevention of ASCVD, such as further lipid control, inflammation management, lifestyle and weight optimization, strict diabetes control, use of β-blockers, use of renin-angiotensin-aldosterone system inhibitors, vaccinations, …


A Comparative Analysis Of The Past Three Fifa World Cups: Nations’ Regulations, Policies, And Global Impact, Arturo Flores Jan 2025

A Comparative Analysis Of The Past Three Fifa World Cups: Nations’ Regulations, Policies, And Global Impact, Arturo Flores

History and Political Science | Senior Theses

The current study investigates the relationship between alcohol and sports marketing. Throughout this research paper, the primary focus is to look at the three previous World Cups and their hosting Countries: Brazil, Russia, and Qatar. To do this, the methods that are used to analyze the three countries will consist of a collection of digital archives consisting of YouTube ads, alcohol policies of the countries hosting the World Cup, and the effects of the World Cup on the hosts overall. In addition, the study goes into how the alcohol policies of each country have shifted before, during, and after being …


Virginia Woolf And The Lesbian Literary Tradition, Hunter Candrian-Velez Jan 2025

Virginia Woolf And The Lesbian Literary Tradition, Hunter Candrian-Velez

English and Creative Writing | Senior Theses

Modernist English authors, such as Virginia Woolf in her novel Orlando: A Biography, built upon a pre-existing and long tradition of underground lesbian literature dating back to Sappho in Ancient Greece. Before Woolf, female writers of the 19th century continued this tradition by establishing the literary trope of the “Victorian Romantic Female Friendship,” which would later take on different shapes and connotations with discoveries made in the early 1900s related to sexology and homosexual inversion. These discoveries would lead writers to code their work in the hopes of avoiding censorship and government punishment. Writers such as Virginia Woolf, Elizabeth Gaskell, …


Exposed! Students’ Personal Reproductive Healthcare Information, Janet Levit Jan 2025

Exposed! Students’ Personal Reproductive Healthcare Information, Janet Levit

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Interpretive Rules Are The New Regulations: Agency Guidance After Loper Bright, Gwendolyn Savitz Jan 2025

Interpretive Rules Are The New Regulations: Agency Guidance After Loper Bright, Gwendolyn Savitz

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Designing Tpack-Driven Mobile Learning With Digital Citizenship For Biology Education: Insights From Ngt And Ism Approaches, Cik Jamaliah Abd Manaf, Shakinaz Desa, Muhamad Ikhwan Mat Saad, Helen Crompton Jan 2025

Designing Tpack-Driven Mobile Learning With Digital Citizenship For Biology Education: Insights From Ngt And Ism Approaches, Cik Jamaliah Abd Manaf, Shakinaz Desa, Muhamad Ikhwan Mat Saad, Helen Crompton

STEMPS Faculty Publications

The rapid digitization of education and the complexity of scientific content demand the integration of digital citizenship in TPACK-based mobile learning for Biology. This study aimed to identify and prioritize relevant digital citizenship practices using a Design and Development Research approach. In Phase One, the Nominal Group Technique with 10 experts evaluated eight proposed practices. Phase Two employed Interpretive Structural Modeling with nine experts to structure hierarchical relationships. Seven practices were retained, with Ethical Use of Digital Resources as the top-level driver. The resulting framework supports ethical and discipline-specific mobile learning models, promoting responsible digital engagement in Biology education.


Lived Experiences Of Marginalized Pre-Service Teachers' Technology Ownership And Acquisition Of Digital Skills, Jerolyn Brown, Tian Luo Jan 2025

Lived Experiences Of Marginalized Pre-Service Teachers' Technology Ownership And Acquisition Of Digital Skills, Jerolyn Brown, Tian Luo

STEMPS Faculty Publications

Aim/Purpose

Despite increasing access to technology, persistent disparities in digital competence and self-efficacy remain among marginalized pre-service teachers, often exacerbated by systemic inequities and the digital divide. This research explores the gap in knowledge of the lived experiences of marginalized pre-service teachers’ (PST) prior access to technology and their current perceptions about educational technology integration.

Background

Grounded in Sociocultural Theory and the Theory of Planned Behavior, this study seeks to answer how marginalized pre-service teachers perceive prior and current technology ownership and related skill acquisition, what beliefs and intentions they have for future classroom technology integration, and what systemic disparities …


Problem-Solving Training To Improve Caregiver Burden And Depressive Symptoms Among Dementia Caregivers: Personal And Clinical Factors Of Responders Vs. Non-Responders, Shannon B Juengst, Matthew Lee Smith, Kristin Wilmoth, Brittany Wright, Gang Han, Charlene Supnet, Gladys Maestre Jan 2025

Problem-Solving Training To Improve Caregiver Burden And Depressive Symptoms Among Dementia Caregivers: Personal And Clinical Factors Of Responders Vs. Non-Responders, Shannon B Juengst, Matthew Lee Smith, Kristin Wilmoth, Brittany Wright, Gang Han, Charlene Supnet, Gladys Maestre

2020-Current year OA Pubs

INTRODUCTION: Metacognitive strategy training interventions, like Problem-Solving Training/Descubriendo Soluciones Juntos (PST/DSJ), have efficacy for improving caregiver burden and depressive symptoms. We previously demonstrated that PST/DSJ improved caregiver burden and depressive symptoms among caregivers of adults with Alzheimer's Disease and related dementias (ADRD), regardless of the number of sessions or boosters received. However, these results did not examine factors characterizing those who responded (improvement in caregiver burden or depressive symptoms) or did not respond to the intervention.

OBJECTIVE: To identify key personal and clinical factors associated with response to PST/DSJ. Personal factors included age, gender, race, Hispanic ethnicity, education, and employment …


Usft 2025-2026 Usf Libraries Annual Report, Usf Libraries Jan 2025

Usft 2025-2026 Usf Libraries Annual Report, Usf Libraries

Library Annual Reports

No abstract provided.


Strabismus And Amblyopia Disrupt Spatial Perception But Not The Fidelity Of Cortical Maps In Human Primary Visual Cortex, D. Schluppeck, D. Arnoldussen, Z. Hussain, J. Besle, S. T. Francis, P. V. Mcgraw Jan 2025

Strabismus And Amblyopia Disrupt Spatial Perception But Not The Fidelity Of Cortical Maps In Human Primary Visual Cortex, D. Schluppeck, D. Arnoldussen, Z. Hussain, J. Besle, S. T. Francis, P. V. Mcgraw

School of Psychology

Amblyopia is a common disorder of spatial vision and is frequently associated with the presence of anisometropia, strabismus, or both, during visual development. For highly visible stimuli, subjects with strabismic amblyopia often report marked spatial distortions, but the neural basis of this supra-threshold deficit is not well understood. Here, we used a combination of behavioural measurements and visual field mapping with high spatial-resolution functional magnetic resonance imaging (fMRI) at 7 T to assess perceptual distortions in 12 participants with strabismic amblyopia and 9 control subjects. We measured both behavioural and cortical visual field maps monocularly through each eye. Although amblyopic …