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Il-7: A Potential Next-Generation Adjuvant For Immune Cell Therapies, Richard S Hotchkiss, John F Dipersio, Cassian Yee, Russell K Pachynski, Marcel R M Van Den Brink

2020-Current year OA Pubs

Cell-based immune therapies ranging from CAR-T cells to tumor infiltrating lymphocytes (TILs) and endogenous T-cell products, have produced unprecedented clinical responses in hematologic malignancies and are currently under active investigation for solid tumors. Nevertheless, several key challenges continue to limit the durability and breadth of clinical benefit. IL-7 is a pleiotropic cytokine that increases both the number and function of lymphocytes. Although not yet clinically approved, IL-7 has been used in over 620 adult and pediatric patients for a variety of reasons including, for example, to hasten bone marrow recovery after allogenic stem cell transplantation, to reverse lymphopenia due to …

"I Feel Like People Would Look At Me Like I'M Dirty Or Like I'M A Thief:" A Qualitative Exploration Of Interpersonal And Intrapersonal Experiences That Influence Recovery Among Adults At Risk Of Opioid-Related Overdose, Hannah S Szlyk, Sara Jones, Jordan Michener, Zhuoran Zhang, Nina Kaiser, Heidi Holtz, Melody Rachel Konadu Frempong, Husain Lateef, William Hutson, Patricia Cavazos-Rehg

2020-Current year OA Pubs

OBJECTIVE: Due to the nature of early termination of treatment and the transient lifestyles of many people who use substances, many providers are unaware of the factors that may have contributed to their client's engagement in treatment. Treatment providers and researchers need a better understanding of intrapersonal and interpersonal factors that impact recovery from the clients' perspective. This study uses qualitative methods to explore these factors.

METHODS: Eligible participants were adults who had used opioids and/or stimulants and were receiving treatment at a consenting facility. Participants completed one-month follow-up interviews after using a mobile health intervention. Transcripts were analyzed using …

Obesity, Metabolic Health, And Diabetic Complications In People With Type 1 Diabetes., Yuanjie Mao, Jen-Tzer Gau, Ning Jiang

Ambulatory and Primary Care Articles

AIM: The concept of metabolically healthy obesity (MHO) has not been studied in type 1 diabetes (T1D). By analysing datasets from the DCCT/EDIC study, we compared the development of diabetic complications by obesity and metabolic health over 30 years of follow up.

MATERIALS AND METHODS: Insulin resistance was calculated by estimated glucose disposal rate (eGDR). The participants (n = 1127) were then divided into four groups based on time-weighted mean body mass index and mean eGDR: metabolically healthy non-obesity (MHN, n = 874), metabolically unhealthy non-obesity (MUN, n = 66), MHO (n = 146) and metabolically unhealthy obesity (MUO, n …

Petechiae And A Persistent Violaceous Nodule: A Presentation Of Blastic Plasmacytoid Dendritic Cell Neoplasm To Dermatology., Madison Anzelc, Christina Druskovich, Austin Cusick, Matthew Franklin

Ambulatory and Primary Care Articles

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive CD4+ CD56+ hematopoietic malignancy. The cutaneous presentation is variable but often includes violaceous nodules. We present a rare case of BPDCN, which featured dermatological findings consisting of erythematous macules, petechiae, purpura, and a violaceous nodule. A skin biopsy and peripheral blood smear supported a diagnosis of BPDCN. With BPDCN favoring cutaneous involvement, we urge dermatologists to be aware of the possibility of a BPDCN diagnosis in patients who present with purpuric nodules and petechial skin findings, especially when it is not easily explainable by another pathology or medication.

Editors’ Introduction: 25th Anniversary Issue Of The Jiws, Diana J. Fox, Kimberly Chabot Davis, Priyanka Tripathi, Catherine Ndinda

Journal of International Women's Studies

No abstract provided.

Modernity, Domesticity, And Women’S Subjectivity: A Comparative Study Of The Fiction Of Jane Austen And Ling Shuhua, Rou Li

Journal of International Women's Studies

This study examines how Jane Austen and Ling Shuhua represent women’s conceptions of selfhood through domestic narratives during periods of modernization in their respective societies. Drawing on Anthony Giddens’ theory of modern intimacy and Gary Kelly’s analysis of the bourgeois cultural revolution, this comparative analysis explores how their works reflect broader societal transformations through the depiction of intimate domestic spaces. Through detailed textual analysis of Austen’s novel Pride and Prejudice and several of Ling Shuhua’s short stories in Collected Essays of Ling Shuhua, this study demonstrates how both authors employ domestic settings not merely as backdrops but as dynamic …

Unveiling The Vulnerability Of Return Migration: A Feminist Embeddedness Perspective On Bangladeshi Women Workers, Faraha Nawaz, Tania Afrin Tonny

Journal of International Women's Studies

This study explores the vulnerability of migrant workers returning to Bangladesh through the lens of van Houte and Davids’ (2008) embeddedness framework. Centering women’s narratives offers a feminist method of embeddedness, focusing on the economic, social, and psychosocial dimensions of returning migrants’ experiences. This paper addresses the vulnerabilities experienced by women upon their return, particularly those returning from the Middle East. Drawing on qualitative data from in-depth interviews with 30 Bangladeshi women domestic workers, this study identifies two primary causes for their return from the Middle East to Bangladesh: coercion by family members and coercion by employers. The findings indicate …

Migration And Work: An Intersectional Perspective On Women Workers In Brick Kilns In The Sivasagar District Of Assam, India, Kashmiri Saikia, Sikha Das

Journal of International Women's Studies

This paper is based on fieldwork regarding brick kiln workers in the Sivasagar district of Assam, located in Northeast India. Apart from family migration, women migrate alone to these brick kilns in search of work opportunities. Despite progress, evidence suggests that many women who work in brick kilns are not afforded workplace rights and are underrepresented, unregistered, and paid lesser wages compared to men workers. Many kilns are unregulated and remain outside the purview of workplace laws. Through interviews and conversations with women workers, this paper aims to understand and analyse the dynamics of gender, migration, and work in the …

Recasting Gender Roles: The New Woman And The New Man In Women-Centred Contemporary Malayalam Films, Roshan B. Karimpaniyil, Shashikantha Koudur

Journal of International Women's Studies

This article examines the representation of gender roles in select women-centred contemporary Malayalam films. It attempts to expand on the idea of the “new Indian woman” and develop a concept of the “new Indian man.” The new Indian woman is a byproduct of the cultural metamorphosis caused by liberalisation, while the new Indian man could be understood as the product of modern culture’s attempt to undermine traditional masculinity. By analysing the movies Biriyaani (2020), The Great Indian Kitchen (2021), Aanum Pennum (2021), and Sara’s (2021), as well as the short films Memories of a Machine (2016), Freedom @ Midnight (2021), …

Al-Rawabi School For Girls: The Arab Mean Girls?, Leen Masoud

Journal of International Women's Studies

Released in 2021 on Netflix and directed by Jordanian actress and director Tima Shomali, the television series Al-Rawabi School for Girls garnered international attention for its daring depiction of Jordanian girlhood and discussions of hard-hitting topics such as bullying, domestic abuse, sexual harassment, and honor killings. Despite its Jordanian context, the series engaged heavily with Hollywood tropes regarding girlhood, specifically the “mean girl” trope; the show referenced this trope so often that it began to be called “the Arab Mean Girls,” referring to the cult classic US film Mean Girls (2004). This essay critically examines the utilization of popular …

“Western Feminism” Is Not A Slur, But It Is A Monolith, Diana Fox

Journal of International Women's Studies

No abstract provided.

Book Review: Memory, Voice, And Identity: Muslim Women’S Writing From Across The Middle East, Mohammed Yassin Mohd Aba Sha’Ar

Journal of International Women's Studies

No abstract provided.

Book Review: Ethical Encounters: Transnational Feminism, Human Rights, And War Cinema In Bangladesh, Masrufa Nusrat

Journal of International Women's Studies

No abstract provided.

Book Review: Janet Jagan: Freedom Fighter Of Guyana, Suzanne C. Persard

Journal of International Women's Studies

No abstract provided.

Film Review: Breasts And Body Politics In B 32 Muthal 44 Vare, Aswathy A., Meenu B.

Journal of International Women's Studies

No abstract provided.

Chromium Removal From Tannery Wastewater Via A Hydroponic Technique With Vetiver Grass (Vetiveria Zizanioides), Ismot Zereen, Zainul Abedin, Siddikur Rahman, Debasish Pandit

Applied Environmental Research

This research aimed to investigate the effects of hydroponically cultivated vetiver grass (Vetiveria zizanioides) on the treatment of tannery wastewater for chromium (Cr) removal in Bangladesh. The field experiment involved 9 containers, which were separated into 3 groups: tannery wastewater with hydroponically planted vetiver, tannery wastewater without vetiver (control), and a group with vetiver grown in tap water. The tap water group was used solely for plant growth assessment, whereas only the control and hydroponic vetiver groups were evaluated for Cr and water quality parameters. Throughout the 45-day trial period, Cr and other water quality parameters were analyzed …

Enhanced Co2 Capture Performance Using Methyl Diethanolamine-Functionalized Silica Gels: Assessing Co2 Capture Capacity, Petpitcha Boonmatoon, Pacharapol Nokpho, Pornpote Piumsomboon, Benjapon Chalermsinsuwan

Applied Environmental Research

Carbon dioxide (CO2) is a significant greenhouse gas. This causes harm to the environment and to humans. In 2023, atmospheric CO2 levels rose to 420 ppm, marking a new record high. Therefore, technology for capturing CO2 has been developed. At present, a wide variety of technologies have been proposed to capture CO2. Adsorption technology is more affordable and requires less energy for regeneration. There are many potential solid adsorbents for CO2 capture, such as zeolites, alumina, metal‒organic frameworks (MOFs), and mesoporous silicas. Silica materials possess unique properties that make them promising candidates as solid sorbents for CO2 capture. They provide …

Government Support And Local Residents’ Behavior In E-Waste Management: Evidence From Thailand, Peeranart Kiddee, Somsiri Decharat, Suttiporn Bunmak

Applied Environmental Research

Electronic waste (e-waste) management is a critical global pollution concern. This study investigates government support; local residents' perceptions, knowledge, attitudes, and behaviors related to e-waste management; and collaborative governance in southern Thailand. Employing both quantitative and qualitative methods, this research involves expert government officers who are well versed in e-waste management and local residents. The study utilized in-depth interviews, questionnaires, and workshops. The results revealed that the government is responsible for four e-waste management approaches, encompassing various e-waste collection, transportation, and disposal methods. Local residents exhibited low perceptions of e-waste news but possessed substantial knowledge and positive attitudes toward e-waste …

Examining The Variability In Planetary Boundary Layer Height Over Thailand: Correlations With Enso And Aerosol Optical Depth, Sirapong Sooktawee, Khwanruthai Renuhom, Siriwan Kaewket, Aduldech Patpai, Pramet Kaewmesri, Thongchai Kanabkaew, Pichnaree Lalitaporn

Applied Environmental Research

Thailand has been facing air pollution, e.g., PM2.5, and impacts from climate phenomena, e.g., the El Niño‒Southern Oscillation (ENSO). Both air pollution and climate interact with each other. Changes in the planetary boundary layer height (PBLH) can affect PM2.5, represented by the aerosol optical depth (AOD), and are influenced by ENSO related to changes in the PBLH. The relationships among the PBLH, ENSO, and AOD were investigated via an empirical orthogonal function (EOF), which decomposes the spatiotemporal data of the PBLH into spatial patterns and corresponding time series. Correlation analysis was used to determine the relationships between the PBL variability …

Spatial And Temporal Pattern Assessment Of Agricultural Drought Sensitivity And Its Potential Impact On Economic Crops In Nakhon Ratchasima, Thailand, Suwit Ongsomwang, Siripon Kamontum

Applied Environmental Research

Agricultural drought sensitivity (ADS) is highly diverse across regions, primarily due to differences in climate, soil types, and farming practices. Agricultural drought impacts depend on drought intensity, severity, duration and timing relative to crop growth stages. Therefore, spatial and temporal pattern assessments of ADS and its potential impact on economic crops in three scenarios via multicriteria decision-making methods were conducted. As a result, the spatial distributions of the ADS index and its classification at 3 m7, 3 m10 and 6 m10, covering the planting and growing periods, displayed different patterns. The percentages of moderate, high and very high severity levels …

Exploring The Co-Composting Potentials Of Raw Grease Trap And Grease Trap-Derived Soaps: Insights Into Grease Trap Modification, Calcium Supplementation, And Microbial Community Analysis, Pokchat Chutivisut, Panaya Kotchaplai, Bualuang Faiyue, Nattapong Tuntiwiwattanapun

Applied Environmental Research

Managing waste with grease traps poses a challenge because of the potential environmental issues associated with its disposal. In this study, two approaches were investigated to increase the biodegradability of grease trap waste: 1) converting raw grease trap waste into soap and 2) supplementing grease trap soap as inoculum with calcium material. The preparation of grease trap soap was optimized to attain a soap yield of 103% by utilizing a water-to-ethanol ratio of 9:1 at 80 °C for a processing time of 3 hours. A comparison of the composting results revealed higher nitrate yields with increased ratios of grease trap …

Nationwide Household Food Waste Generation Rates In Rural And Urban Settings: Evidence In Thailand, Vilasinee Krutprong, Chanathip Pharino

Applied Environmental Research

To achieve sustainable development goals, addressing food waste requires evidence-based solutions grounded in a nuanced understanding of waste generation rates and the factors influencing them. This study explores the intricate dynamics of food waste generation in Thai households, encompassing both liquid and solid waste streams. Empirical data were collected from 2,700 diverse households across urban and rural areas over a four-week period. The study revealed an average food waste generation rate of 0.332±0.003 kg per capita per day when liquids were included and 0.228± 0.002 kg per capita per day when liquids were excluded. Surprisingly, rural households generated more food …

The Role Of Remittances In Economic Growth And Environmental Sustainability: A Cross-Country Analysis, Bishnu B. Khatri, Omkar Poudel, Pradeep Acharya

Applied Environmental Research

Although remittances significantly influence economic stability, their role in sustainable growth and environmental impact remains uncertain. While these financial inflows enhance household welfare, their effects on gross domestic product (GDP), carbon emissions, and trade openness require further exploration. This study investigates the economic and environmental linkages of remittances in India, Mexico, China, the Philippines, and Pakistan, the top five remittance-receiving countries. Using panel data analysis, this study employs Dumitrescu Hurlin causality tests and dynamic ordinary least squares (DOLS) to assess the long-term and causal relationships between urbanization, trade openness, GDP per capita, carbon emissions, and remittances. Data from the World …

Microplastic Contamination In Commercially Important Bivalves Of Sorsogon Bay, Philippines, Sarina M.B. Arciga, Charmaine A. Malon, Kenneth N. Ballaran

Applied Environmental Research

Sorsogon Bay, a key fishing ground in the Philippines, is known for its commercially important bivalve species: Perna viridis, Atrina pectinata, and Paphia undulata. Despite their ecological and economic value, limited research has been conducted on microplastic contamination in bivalves harvested from this area. This study aimed to assess the abundance and types of microplastics in commercially important bivalves (P. viridis, A. pectinata, and P. undulata) from Sorsogon Bay, Philippines. Commercial bivalve samples were randomly collected, digested with 10% w/v potassium hydroxide (KOH) solution, filtered (8 µm), and examined under a compound microscope. …

Sediment Grain Size Analysis And Characteristics Of Sedimentation Processes In The Bang Berd-Khao Tham Thong Beach, Chumphon Province, Rawadee Meeprasit, Sujaree Bureekul, Suriyan Saramul

Applied Environmental Research

This study investigated the sedimentological characteristics of the Bang Berd-Khao Tham Thong beach system, which is located along the western shore of the central Gulf of Thailand, an area that is minimally disturbed by human activity and is ideal for studying natural coastal processes. Sediment samples were collected from both coastal and marine environments across four sampling periods (July 2022, September 2022, April 2023, and June 2023). The analysis focused on the grain size distribution, sorting, skewness, kurtosis, and sediment composition, revealing a predominance of medium sand in coastal sediments and increased silt and clay contents in marine sediments. The …

Effects Of Herbicides On 2,4-D-Resistant Soil Microorganisms In Maize Cultivation In Lopburi Province, Thailand, Boontarik Chimchart, Jitra Kokaew, Amnat Eamvijarn, Kanokon Bunpha, Sontaya Khamtib, Monchai Manassila, Tawatchai Inboonchuay

Applied Environmental Research

This study aimed to assess the impact of herbicide application on soil micro-organism density and to identify microorganisms resistant to 2,4-D-dimethyl-ammonium (2,4-D) for potential biodegradation. Research was conducted in maize plots in Lopburi Province, where 2,4-D was applied at a rate of 120 g of active ingredient per 160 m2. The soil samples were collected at various intervals: before application; 2 and 4 hours postapplication; and 1, 3, and 7 days after application. The analyses included soil property and microorganism population analyses. The results indicated that 2,4-D applications significantly increased bacteria and fungi in the treated plots compared with those …

Low-Temperature Catalytic Oxidation Of White Spirit Vapor In Air By Binary Oxides Of Feo-Mnox Supported On Oms-2 Material, Ngo Quoc Nguyen, Pham Duy Quang, Nguyen Ha Nhu, Le Thi Van Anh, Nguyen Thi Thuy, Vo Thanh Hang, Le Van Thang, Nguyen Thi Le Lien, Nguyen Trung Thanh, Nguyen Nhat Huy

Applied Environmental Research

In this work, catalysts of iron and manganese oxides supported on OMS-2 were prepared and applied to remove white spirit (WS) in air. Among the fabricated catalysts, the FeO-MnOx/OMS-2 catalyst with a surface Fe+Mn loading of 15% (Fe:Mn = 6:4) exhibited the highest catalytic performance, achieving a high WS removal efficiency of 97.91% at 200 °C. The catalyst retained the cryptomelane-type tunnel structure of OMS-2 and possessed enhanced redox activity due to the synergistic interaction between surface Fe and Mn species. The physico-chemical properties were characterized via BET, EDS, FTIR, XRD, and SEM. The suitable conditions for WS oxidation were …

Investigating Spatial And Temporal Changes In Vegetation Via Remote Sensing Indicators And Revealing Their Trends In The Central Desert Of Iran, Peyman Akbarzadeh, Shima Nikoo, Mehran Akbarzadeh

Applied Environmental Research

Vegetation changes can significantly affect the conditions and productivity of ecosystems. Consequently, studying vegetation dynamics across various temporal and spatial scales has emerged as a critical environmental concern. The aim of this study was to investigate changes in vegetation cover via vegetation indices, including the normalized difference vegetation index (NDVI), ratio vegetation index (RVI), soil adjusted vegetation index (SAVI), and difference vegetation index (DVI), derived from multitemporal Landsat 5, 7, and 8 satellite images processed via the Google Earth Engine. The study area is located in the Damghan arid and desert watershed, which represents the central desert of Iran. Furthermore, …

Halotolerant Biodegradation And Detoxification Of Synthetic Dyes By Marine-Derived Penicillium Oxalicum M6a: Metabolite Profiling And Ecotoxicity Assessment, Ugochukwu Okechukwu Ozojiofor, Mohammed Sani Abdulsalami, Nkechi Eucharia Egbe, Ahmed Ali Haroun, Yakubu Magaji

Applied Environmental Research

The complex aromatic structures of synthetic dyes in contaminated water bodies make them difficult to degrade, posing a serious environmental challenge and representing a significant emerging pollutant that warrants urgent intervention. This study evaluated the biodegradation and detoxification potential of a halotolerant, marine-derived fungal strain, Penicillium oxalicum M6A, isolated from the Nigerian coastline, against Indigo carmine (IC) and Remazol Brilliant Blue R (RBBR). The effects of pH, temperature, salinity, and dye concentration on degradation efficiency, alongside enzymatic activity, were assessed. FTIR and GC‒MS analyses were employed to identify degradation products and predict metabolic pathways, whereas toxicity was evaluated in three …

Kinetics Of Hexavalent Chromium Adsorption And Reduction By Living Cells Of The Marine Bacterium Bacillus Cereus, Jittima Charoenpanich, Wachiraphorn Cherdchoo, Jutamas Pantab, Jariya Supakrit

Applied Environmental Research

This study identified Bacillus cereus, an efficient Cr(VI) bioreducer, isolated from marine sediment in Thailand. Batch experiments verified the complete removal of 25 mg L-1Cr(VI) from synthetic wastewater (pH 7.0) after 6 days at 37 °C, 50 rpm,and a biomass concentration of 25% (v/v) culture inoculum. The Freundlich isotherm model demonstrated the best correlation with the Cr(VI) adsorption equilibrium data in the 25–100 mg L-1concentration range (R2= 0.9831). Kinetic analyses indicated that the removal of Cr(VI) by living B. cereusfollowed a pseudo-second-order adsorption model (R2= 0.9875) and a pseudo-second-order reduction model (R2= 0.9807). The adsorption rate can be accuratelycharacterizedvia the …