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2025

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Mcsa Forum Minutes 09/28/2025, Morris Campus Student Association Sep 2025

Mcsa Forum Minutes 09/28/2025, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.


The Effects Of Mangosteen Pericarp (Garcinia Mangostana Linn.) Extract On Necrotic And Apoptotic Cells In A Periodontitis Model Following X-Ray Exposure, Deny Saputra, Sri Wm. Mulyani, Rini D. Ridwan, Eha R. Astuti, Nastiti F. Ramadhani, Hafshah Zs. Hanun, Kurnia C. Muslimah, Faiza M. Rusdi, Tengku Nebta. Noor Sep 2025

The Effects Of Mangosteen Pericarp (Garcinia Mangostana Linn.) Extract On Necrotic And Apoptotic Cells In A Periodontitis Model Following X-Ray Exposure, Deny Saputra, Sri Wm. Mulyani, Rini D. Ridwan, Eha R. Astuti, Nastiti F. Ramadhani, Hafshah Zs. Hanun, Kurnia C. Muslimah, Faiza M. Rusdi, Tengku Nebta. Noor

Journal of Dentomaxillofacial Science

Objective: To evaluate the effect of mangosteen (Garcinia mangostana Linn.) pericarp extract application on necrotic and apoptotic cell counts in an experimental periodontitis model following X-ray exposure.

Material and Methods: A total of 35 male Rattus norvegicus were randomly assigned to seven experimental groups. Mangosteen pericarp extract was obtained via maceration, and a mucoadhesive gingival patch was formulated using the solvent casting technique. Following group-specific interventions and X-ray irradiation, mandibular tissue samples were harvested, processed histologically, and stained with hematoxylin and eosin. The microscopic examination was performed to quantify necrotic and apoptotic cells. Data were analyzed using one-way …


Autogenous Bone Graft From Alvolar Exostosis With Combination Of Xenograft And Platelet-Rich Fibrin For Treatment Of Intrabony Defects: A Case Report, Nurul H. Danial, Sitti R. Juanita, Endo Sadewa, Dian Setiawati, Venda N. Rianta Sep 2025

Autogenous Bone Graft From Alvolar Exostosis With Combination Of Xenograft And Platelet-Rich Fibrin For Treatment Of Intrabony Defects: A Case Report, Nurul H. Danial, Sitti R. Juanita, Endo Sadewa, Dian Setiawati, Venda N. Rianta

Journal of Dentomaxillofacial Science

Introduction: Intrabony defects are the result of periodontal destruction and are associated with the progression of periodontitis. This case report describes the treatment of an intrabony defect using autograft from alveolar exostosis combined with xenograft and platelet-rich fibrin (PRF). Case Report: A 55-year-old man came with complaints of his right upper back teeth being mobile and feel uncomfortable when eating since five months ago. Clinical examination revealed an average pocket depth 6 mm and average tooth mobility 2 degree. On radiographic examination, vertical bone defects were found. The patient received initial therapy followed by surgical flap surgery using autograft from …


Comparative Assessment Of Malocclusion In The Sagittal Plane Based On Clinical Dental And Skeletal Characteristics, Vyzhenko Yevhenii, Kuroiedova Vira, Halych Liudmila, Makarova Oleksandra Sep 2025

Comparative Assessment Of Malocclusion In The Sagittal Plane Based On Clinical Dental And Skeletal Characteristics, Vyzhenko Yevhenii, Kuroiedova Vira, Halych Liudmila, Makarova Oleksandra

Journal of Dentomaxillofacial Science

ABSTRACT

Objective: The aim of this study was to provide a comparative assessment of sagittal malocclusion based on clinical dental and skeletal characteristics in a sample of the Ukrainian population and to identify cephalometric variables that are contributing factors in the formation of malocclusion in the sagittal plane.

Material and methods: The study included 200 subjects with malocclusion, aged 9–20 years. Clinical sagittal molar occlusion was determined according to Angle’s classification. Skeletal characteristics were classified based on the ANB angle. Cephalometric analysis was performed using cone-beam computed tomography. Statistical analysis was conducted using the Shapiro-Wilk hypothesis test with …


Correlation Of Actn3 R557x And Q523r Gene Polymorphism On Skeletal Patterns In Indonesian Subpopulations (Laboratory And Lateral Cephalometry Study), Ninis Y. Wulandari, Fadli Jazaldi, Nurtami Soedarsono, Maria Purbiati Sep 2025

Correlation Of Actn3 R557x And Q523r Gene Polymorphism On Skeletal Patterns In Indonesian Subpopulations (Laboratory And Lateral Cephalometry Study), Ninis Y. Wulandari, Fadli Jazaldi, Nurtami Soedarsono, Maria Purbiati

Journal of Dentomaxillofacial Science

Background: The protein Alpha-actinin-3 (ACTN3) is an actin-binding protein that influences muscle performance and the proportion of muscle fiber types in human skeletal muscle, including masticatory muscle. Previous studies have incorporated muscle fiber type into craniofacial development that may lead to malocclusion.

Aim: To determine the correlation between polymorphisms of ACTN3 R557X and Q523R gene on skeletal patterns in Indonesian Subpopulations.

Materials and methods: Subjects are patients with class I, II, and III skeletal malocclusion at the Faculty of Dentistry Universitas Indonesia with a total of 171 patients involved. Research samples consisted of 10 hair follicles and lateral cephalometric …


Adipose Tissue Insulin Resistance: A Key Driver Of Metabolic Syndrome Pathogenesis, Atefeh Rabiee, Md A. Hossain, Ankita Poojari Sep 2025

Adipose Tissue Insulin Resistance: A Key Driver Of Metabolic Syndrome Pathogenesis, Atefeh Rabiee, Md A. Hossain, Ankita Poojari

Pacific Faculty Work

Metabolic syndrome (MetS), characterized by obesity, insulin resistance, dyslipidemia, and hypertension, is a growing global health concern. This review examines the relationship between adipose tissue insulin resistance (AT-IR) and MetS. Adipose tissue functions beyond energy storage as an endocrine organ that regulates metabolism through hormone and cytokine secretion. When adipose tissue becomes insulin resistant, it contributes to systemic metabolic dysfunction through impaired glucose uptake and dysregulated adipokine production. This creates a bidirectional relationship where AT-IR promotes MetS development, while MetS-associated inflammation further worsens adipose insulin sensitivity. Key mechanisms include inflammatory signaling, altered adipokine profile, and mitochondrial dysfunction. Understanding these interactions …


Serum Factors In Primary Podocytopathies, Edward J. Filippone, John L. Farber Sep 2025

Serum Factors In Primary Podocytopathies, Edward J. Filippone, John L. Farber

Division of Nephrology Faculty Papers

Primary podocytopathies, including minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS), are caused by a circulating factor or factors injurious to the podocyte. An immunologic origin seems likely based on responsiveness to corticosteroids or other immunosuppressive agents, including calcineurin inhibitors targeting T-cells and rituximab targeting B-cells. Potential non-antibody-mediated circulating factors have been identified, including cardiotrophin-like cytokine 1, soluble urokinase plasminogen activator receptor, and angiopoietin-like 4, among others. More recent research supports a primary antibody pathogenesis, with anti-nephrin antibodies found in a significant percentage of cases. Such antibodies also predict recurrence after transplantation. Other potential antigenic targets besides nephrin include …


Defining Marketing In The Digital Age: An Opportunity To Advance Marketing Thought And Practice, Norman Mafuratidze, Marius Wait, Ilse Struweg Sep 2025

Defining Marketing In The Digital Age: An Opportunity To Advance Marketing Thought And Practice, Norman Mafuratidze, Marius Wait, Ilse Struweg

The Qualitative Report

Our study consolidates and refines diverse marketing definitions that have emerged over six decades to formulate a contemporary definition encapsulating the discipline’s current practices and theoretical advancements. We investigate how diverse conceptualizations of marketing can be synthesized into a modern definition that accurately reflects current practices and theoretical advancements while providing practical guidance. Using qualitative document analysis methodology, we conducted first- and second-cycle coding on existing marketing definitions from academic literature and industry publications, identifying recurring themes through thematic analysis. Our findings reveal that marketing can be effectively conceptualized through the DIVE framework (Dynamism, Interconnectivity, Value co-creation, and Exchange), positioning …


Plant-Based Extracts And Biocompatible Materials In Dental Tissue Regeneration: An Editorial Review, Muhammad Ikbal, H. Hasanuddin, Acing H. Mude, Erni Marlina, Muhammad Ruslin Sep 2025

Plant-Based Extracts And Biocompatible Materials In Dental Tissue Regeneration: An Editorial Review, Muhammad Ikbal, H. Hasanuddin, Acing H. Mude, Erni Marlina, Muhammad Ruslin

Journal of Dentomaxillofacial Science

Background: This editorial review systematically examines the current issue of The Journal of Dentomaxillofacial Science, highlighting the growing importance of biocompatible materials and plant-based extracts in dental regenerative therapies.

Method: Modulation of growth factors, including VEGF, FGF-2, and TGF-β, is crucial for improving tissue repair and regeneration in dental treatments. The studies reviewed show that combining plant extracts, such as galam leaf, with tricalcium silicate cement enhances growth factor expression and promotes angiogenesis, odontoblast differentiation, and fibroblast proliferation.

Results: Modulation of growth factors significantly accelerated tissue healing and regeneration. The integration of biocompatible materials and plant-based extracts has a significant …


Body Mass Index And Dental Caries Among Indonesian Adults: A Survey-Weighted Analysis Of Riskesdas 2018 In Banten Province, Helwiah Umniyati, Nazillah L. Khaer, Nurhanifah Hamdah, Mondastri K. Sudaryo Sep 2025

Body Mass Index And Dental Caries Among Indonesian Adults: A Survey-Weighted Analysis Of Riskesdas 2018 In Banten Province, Helwiah Umniyati, Nazillah L. Khaer, Nurhanifah Hamdah, Mondastri K. Sudaryo

Journal of Dentomaxillofacial Science

Objective: This study aimed to determine the relationship between nutritional status and DMFT among adults in Banten using Riskesdas 2018 data. Material and Methods: The design of this study was cross-sectional, with a total sample of 1580 respondents aged 18-95 years. The relationship between BMI and DMFT was analyzed using Cox regression analysis, controlled for age, gender, educational level, work status, timing of tooth brushing, sweet food consumption, and diabetes mellitus status. Ethical permission was obtained from the YARSI University Research Institute, reference number No: 406/KEP-UY/BIA/XII/2021. Results: The mean DMFT was 8.3 (± 7.9). The prevalence of decay was 87.7%. …


Correlation Of Alpha-Amylase And Orthodontic Pain Perception: Standard Edgewise Vs Straight-Wire Appliances, Elih Sayuti, Ida A. Evangelina, Avi Laviana, Zenith Paskalin, Endah Mardiati, Santhra S. Balan, Ardiansyah Pawinru Sep 2025

Correlation Of Alpha-Amylase And Orthodontic Pain Perception: Standard Edgewise Vs Straight-Wire Appliances, Elih Sayuti, Ida A. Evangelina, Avi Laviana, Zenith Paskalin, Endah Mardiati, Santhra S. Balan, Ardiansyah Pawinru

Journal of Dentomaxillofacial Science

Introduction: Pain is a biological response to orthodontic forces and a major concern during orthodontic treatment. This leads some patients to delay or avoid orthodontic treatment. Pain intensity during orthodontic treatment is generally assessed using the visual analogue scale (VAS). Pain stimulates the sympathetic adrenal medullary system, which increases salivary α-amylase (sAA) secretion. This study aimed to evaluate the relationship between VAS pain intensity and alpha-amylase pain biomarker concentration during the initial stages of orthodontic tooth movement. Methods: This was a cross-sectional study. Fourteen patients requiring orthodontic treatment with maxillary premolar extraction and canine distalization using the Standard Edgewise (SE) …


Capacity Of Gum Arabic As Immunomodulator And Antibacterial Agent Against Oral Cavity Periodontopathogen In Diabetes Mellitus Rats With Periodontitis, Tantin Ermawati, Suhartini, Tecky Indriana, Zahreni Hamzah Sep 2025

Capacity Of Gum Arabic As Immunomodulator And Antibacterial Agent Against Oral Cavity Periodontopathogen In Diabetes Mellitus Rats With Periodontitis, Tantin Ermawati, Suhartini, Tecky Indriana, Zahreni Hamzah

Journal of Dentomaxillofacial Science

Objective: This study aims to determine the benefits of gum arabic as an immunomodulatory and antibacterial drug therapy in the oral cavity of diabetic mellitus rats.

Material and Methods: Male wistar rats induced by diabetes mellitus accompanied by periodontitis and Gum Arabic therapy.  This study was divided into 5 treatment groups, namely group I (control), group II (diabetes mellitus) and group III (diabetes mellitus and periodontitis with P. gingivalis injection), group IV (diabetes mellitus treated with gum arabic), group V (diabetes mellitus with periodontitis and treated with gum arabic). The parameters studied were TNF-α anti-inflammatory mediators and the number of …


The Evaluation Of Variants Within Eight Collagen Genes Col1a1, Col1a2, Col3a1, Col5a1, Col11a1, Col15a1, Col22a1, And Col27a1 And A Risk Of Non-Contact Knee Ligament Rupture In Elite Handball Players: A Case-Control Study, Katarzyna Krawczak-Wójcik, Andrzej Mastalerz, Aleksandra Bojarczuk, Monika Johne, Alison V. September, Aleksandra Garbacz, Katarzyna Komar, Ewelina Maculewicz Sep 2025

The Evaluation Of Variants Within Eight Collagen Genes Col1a1, Col1a2, Col3a1, Col5a1, Col11a1, Col15a1, Col22a1, And Col27a1 And A Risk Of Non-Contact Knee Ligament Rupture In Elite Handball Players: A Case-Control Study, Katarzyna Krawczak-Wójcik, Andrzej Mastalerz, Aleksandra Bojarczuk, Monika Johne, Alison V. September, Aleksandra Garbacz, Katarzyna Komar, Ewelina Maculewicz

Baltic Journal of Health and Physical Activity

Introduction: Knee ligament ruptures are common injuries among athletes. While most previous studies examined single collagen gene polymorphisms, few have investigated haplotype-level associations across multiple genes, particularly in elite handball players. Materials and methods: This case-control study analyzed variants in eight collagen genes (COL1A1, COL1A2, COL3A1, COL5A1, COL11A1, COL15A1, COL22A1, and COL27A1) in 103 elite Polish handball players with non-contact knee ligament rupture and 226 matched controls. Results: The COL22A1 rs11784270 CC genotype was associated with an increased risk (OR = 2.88, p = 0.01), with the strongest effect in the …


Scaling Symmetry Of The Hodgkin-Huxley Mathematical Model, Vladimir Valerievich Galanin Sep 2025

Scaling Symmetry Of The Hodgkin-Huxley Mathematical Model, Vladimir Valerievich Galanin

Progress in Scale Modeling, an International Journal

A computational method based on the application of a scaling transformation to the Hodgkin-Huxley mathematical model of the biological neuron and its generalizations to the case of various neural systems is proposed. The method makes it possible: 1) to obtain invariants of the scaling transformation of the Hodgkin-Huxley model; 2) to find self-similarity regions corresponding to the modes of neural activity; 3) to determine the conditions for the similarity of models of various types of biological neurons; 4) to reduce the order of the system of differential equations of the Hodgkin-Huxley model for neural systems with synchronous activity. The capabilities …


Comparative Transcriptomics Reveals Novel And Differential Circular Rna Responses Underlying Interferon-Mediated Antiviral Regulation In Porcine Alveolar Macrophages, Jiuyi Li, Oluwaseun Adeyemi, Laura C. Miller, Yongming Sang Sep 2025

Comparative Transcriptomics Reveals Novel And Differential Circular Rna Responses Underlying Interferon-Mediated Antiviral Regulation In Porcine Alveolar Macrophages, Jiuyi Li, Oluwaseun Adeyemi, Laura C. Miller, Yongming Sang

Food and Animal Sciences Faculty Research

Porcine Reproductive and Respiratory Syndrome (PRRS) causes significant economic losses in the swine industry. Circular RNAs (circRNAs), a class of stable non-coding RNAs, are increasingly recognized as regulators in immune responses and host–virus interactions. This study investigated the genome-wide circRNA responses in porcine alveolar macrophages (PAMs), key cell targets of PRRSV, following treatment with a modified live virus (MLV) vaccine or two interferon (IFN) subtypes (IFN-α1, IFN-ω5). Using RNA sequencing, we identified over 1000 differentially expressed circRNAs across treatment groups, revealing both conserved and distinct expression profiles. Gene Ontology and KEGG pathway analyses indicated that circRNA-associated genes are significantly enriched …


A Few Millimeters Of Bone: How Male Supremacists Leverage Scientific Sexism To Reinforce Misogynistic Ideologies, Robin O'Hanlon Sep 2025

A Few Millimeters Of Bone: How Male Supremacists Leverage Scientific Sexism To Reinforce Misogynistic Ideologies, Robin O'Hanlon

Publications and Research

In recent years, male supremacist actors have reinforced their misogynistic worldviews by using narrative strategies centered on authoritative “common sense” and scientific “fact.” This paper presents a thematic narrative analysis of The Incel Wiki and the Wiki4Men, representing the first formal analysis of the wiki for the men’s rights organization A Voice for Men. The analysis indicates male supremacists use techniques including misappropriation of scientific information, manipulation of statistics, and leveraging pseudoscientific information to develop their narrative strategies of supremacy. The most consistent narrative strategies of scientific sexism on the wikis are male victimhood, denial of inequality between men and …


Genomic Prediction And Association Mapping Of Early Season Flood Tolerance In Soybean, Caio Canella Vieira, Chengjun Wu, Derrick Harrison, Rafael Marmo, Liliana Florez-Palacios, Andrea Acuna, Daniel Rogers, Samuel B. Fernandes, Igor Fernandes, Grover Shannon, Heng Ye, Henry T. Nguyen Sep 2025

Genomic Prediction And Association Mapping Of Early Season Flood Tolerance In Soybean, Caio Canella Vieira, Chengjun Wu, Derrick Harrison, Rafael Marmo, Liliana Florez-Palacios, Andrea Acuna, Daniel Rogers, Samuel B. Fernandes, Igor Fernandes, Grover Shannon, Heng Ye, Henry T. Nguyen

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Flooding has become a major threat to soybean [Glycine max (L.) Merr.] production as the frequency and intensity of extreme precipitations have been increasing due to climate change. While advances have been made in identifying soybean genetic resources and genomic regions associated with mid-season flood tolerance, there is limited understanding of early season flood tolerance at the vegetative growth stages V2/V4. This study aimed to identify genomic regions associated with early season flood tolerance using a diverse panel of 254 soybean accessions, as well as investigate the viability of implementing genomic prediction models for flood tolerance. Field trials were conducted …


Comparison Of Authentic Urine N-Ethylpentedrone Metabolites To Predicted In Silico And In Vitro Human Hepatocyte Metabolism, Gloria Daziani, Omayema Taoussi, Diletta Berardinelli, Giulia Bambagiotti, Marilyn A. Huestis, Francesco P. Busardò, Jeremy Carlier Sep 2025

Comparison Of Authentic Urine N-Ethylpentedrone Metabolites To Predicted In Silico And In Vitro Human Hepatocyte Metabolism, Gloria Daziani, Omayema Taoussi, Diletta Berardinelli, Giulia Bambagiotti, Marilyn A. Huestis, Francesco P. Busardò, Jeremy Carlier

Institute of Emerging Health Professions Faculty Papers

Synthetic cathinones are the second most common class of substances belonging to the category of new psychoactive substances (NPS). N-ethylpentedrone (NEPD) self-administration was reported, making it important to elucidate its metabolic pathway to improve its detection. NEPD is often taken together with other substances; confidently identifying its intake is important for accurate toxicological analysis and understanding its toxicity. NEPD metabolism was studied following incubation with human hepatocytes and analysis by liquid chromatography-high-resolution mass spectrometry paired with Compound Discoverer software (Thermo Fisher Scientific). Prediction of possible metabolites was performed with the online software GLORYx. In vivo NEPD metabolism was evaluated by …


Outcomes Of The Modified Cabrol Technique In Aortic Root Replacement: Early And Midterm Experience, Nayeem Nasher, Joshua R. Chen, Purab Kothari, Colin King, Jacqueline Mcgee, Vishal Shah, Saarah Khairi, Konstadinos A. Plestis Sep 2025

Outcomes Of The Modified Cabrol Technique In Aortic Root Replacement: Early And Midterm Experience, Nayeem Nasher, Joshua R. Chen, Purab Kothari, Colin King, Jacqueline Mcgee, Vishal Shah, Saarah Khairi, Konstadinos A. Plestis

Department of Surgery Faculty Papers

OBJECTIVES: The modified Cabrol technique has been associated with excellent graft patency. However, prior studies were limited to patients largely on long-term anticoagulation. We sought to analyze outcomes in patients primarily managed without mechanical prostheses.

METHODS: We retrospectively analyzed all patients who underwent aortic root replacement by a single surgeon from 2014 to 2024. Patients who underwent reimplantation of one or both coronary ostia using the modified Cabrol technique with separate interposition grafts were identified. Baseline characteristics and postoperative outcomes were reported. Predictors of mortality were analyzed using Cox proportional hazards, and overall survival was reported using Kaplan-Meier analysis.

RESULTS: …


Growth Plate Skeletal Stem Cells And Their Actions Within The Stem Cell Niche, Natalie Kiat-Amnuay Cheng, Shion Orikasa, Noriaki Ono Sep 2025

Growth Plate Skeletal Stem Cells And Their Actions Within The Stem Cell Niche, Natalie Kiat-Amnuay Cheng, Shion Orikasa, Noriaki Ono

Faculty, Staff and Student Publications

The growth plate is a specialized cartilage structure near the ends of long bones that orchestrates longitudinal bone growth during fetal and postnatal stages. Within this region reside a dynamic population of growth plate skeletal stem cells (gpSSCs), primarily located in the resting zone, which possess self-renewal and multilineage differentiation capacity. Recent advances in cell-lineage tracing, single-cell transcriptomics, and in vivo functional studies have revealed distinct subpopulations of gpSSCs, which are defined by markers such as parathyroid hormone-related protein (PTHrP), CD73, axis inhibition protein 2 (Axin2), forkhead box protein A2 (FoxA2), and apolipoprotein E (ApoE). These stem cells interact intricately …


Analyze The Mechanistic Role Of Lox-1 In Cardiovascular Diseases: A Review, Mohammed Algebory, Zainab Ali Hussein, Amira Shamseldin Mohamed Khalafalla, Emaan Mohammed Zina Sep 2025

Analyze The Mechanistic Role Of Lox-1 In Cardiovascular Diseases: A Review, Mohammed Algebory, Zainab Ali Hussein, Amira Shamseldin Mohamed Khalafalla, Emaan Mohammed Zina

Hilla University College Journal For Medical Science

Cardiovascular disease (CVD) is a major global health concern that leads to illness and death. One of the primary risk factors for CVD is dyslipidemia, which can cause an elevation of oxidized LDL. Recently, the lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1 receptor), a transmembrane protein found in endothelial cells, platelets, cardiomyocytes, and other cells, has gained attention. LOX- 1 receptors are responsible for recognizing oxLDL, and overactivation can trigger pathways that cause tissue damage, including endothelial dysfunction and apoptosis, process under investigation involves the following: promotion of platelet activation and adhesion to endothelial cells; ADP-mediated aggregation; and the development …


The Concept Of Preeclampsia In Biochemistry: Molecular Mechanisms, Oxidative Stress, And Emerging Biomarkers, Dunia Abbas Khudhair, Ammar Hatem Abdullateef, Abbas Hamza Khudhair Sep 2025

The Concept Of Preeclampsia In Biochemistry: Molecular Mechanisms, Oxidative Stress, And Emerging Biomarkers, Dunia Abbas Khudhair, Ammar Hatem Abdullateef, Abbas Hamza Khudhair

Hilla University College Journal For Medical Science

Preeclampsia is a complex, pregnancy-related hypertension condition that significantly endangers mother and fetal health. While its clinical diagnosis is based on hypertension and proteinuria, its origins lie in a cascade of biochemical and molecular disturbances. This review highlights the central concept of preeclampsia from a biochemical perspective, with emphasis on abnormal placental development, oxidative stress, and endothelial dysfunction. Placental hypoxia and an excess of reactive oxygen species (ROS) are caused by inadequate spiral artery remodeling, which also leads to lipid peroxidation and systemic inflammation. A critical biochemical characteristic is the disparity between anti-antigenic (sFlt-1, sENG) and pro-antigenic (PlGF, VEGF) molecules, …


Age-Dependent Associations Of Etanercept And Methotrexate In Stage Ii And Iii Rheumatoid Arthritis Patients, Saif M. Hassan, Zainab Ali Hussein Sep 2025

Age-Dependent Associations Of Etanercept And Methotrexate In Stage Ii And Iii Rheumatoid Arthritis Patients, Saif M. Hassan, Zainab Ali Hussein

Hilla University College Journal For Medical Science

Background: Rheumatoid arthritis (BC) is a complex disease that involves molecular and cellular alterations mediated by endogenous and exogenous factors.

Objectives: This study aimed to determine the osteoblastic and osteoclastic activities at baseline and three months after therapy in RA patients treated with methotrexate (MTX) and Etanercept (ETN).

Methods: investigated the relationship between Etanercept 1 (ETN1) and Methotrexate levels in Rheumatoid arthritis patients positive for cancer antigen 15–3 (CA15-3). This study included 90 patients with stage II and III BC divided into two age groups (25–44 and 45–60 years) and 90 age-matched healthy controls. Serum concentrations of ETN1 and …


"Our River Is Full Of Trash And Many Fish Die" Children's Voices From Pasuruan, Indonesia: Discursive Strategies In Positive Discourse Analysis For Sustainability, Bambang Prastio, Ahsani Maulidina, Agung Rinaldy Malik, Achmad Tantowi Azis Sep 2025

"Our River Is Full Of Trash And Many Fish Die" Children's Voices From Pasuruan, Indonesia: Discursive Strategies In Positive Discourse Analysis For Sustainability, Bambang Prastio, Ahsani Maulidina, Agung Rinaldy Malik, Achmad Tantowi Azis

The Qualitative Report

Addressing river pollution and understanding the role of children in environmental conservation are essential for maintaining ecosystem health and sustainability. This study used positive discourse analysis to explore children's discourse about river pollution in Pasuruan, East Java, Indonesia. Data were collected using walk-and talk ethnographic interviews with 15 children aged 7 to 11 years. The findings reveal that these children employed five discursive strategies: (1) nomination: metaphor, comparison, and cultural practices; (2) predication: positive attitude in the forms of disposition and behavior; (3) argumentation: contrast and parallelism; (4) perspectivisation, involving a type of religious representation that includes references to the …


Early-Life Exposure To Organic Chemical Pollutants As Assessed In Primary Teeth And Cardiometabolic Risk In Mexican American Children: A Pilot Study, Vidya S. Farook, Feroz Akhtar, Rector Arya, Alice Yau, Srinivas Mummidi, Juan Lopez Alvarenga, Alvaro Diaz-Badillo, Roy G. Resendez, John Blangero Sep 2025

Early-Life Exposure To Organic Chemical Pollutants As Assessed In Primary Teeth And Cardiometabolic Risk In Mexican American Children: A Pilot Study, Vidya S. Farook, Feroz Akhtar, Rector Arya, Alice Yau, Srinivas Mummidi, Juan Lopez Alvarenga, Alvaro Diaz-Badillo, Roy G. Resendez, John Blangero

Human Genetics Publications

Early-life exposure to organic chemicals (OCs) may influence childhood obesity and associated cardiometabolic risk. These conditions have been shown to disproportionately affect minority populations such as Mexican Americans (MAs). However, information on the impact of organic chemicals on cardiometabolic risk in MA children is limited. Therefore, we conducted a pilot study to assess the extent to which exposure to organic chemicals influences cardiometabolic traits (CMTs) in MA children. We recalled 25 children from a previous study and collected 25 primary teeth from them. Chemical analyses of the teeth were performed using established protocols. Target analytes included acetaminophen (APAP); 3,5,6-trichloro-2-pyridinol (TCPy), …


Fiber Reinforced Concrete Composites - Seminal Contributions Of Surendra Shah, Vellore S. Gopalaratnam, Wengui Li Sep 2025

Fiber Reinforced Concrete Composites - Seminal Contributions Of Surendra Shah, Vellore S. Gopalaratnam, Wengui Li

C3 Symposium 2025

The authors review the scholarly contributions of Surendra P. Shah during a prolific six-decade academic career in fiber reinforced concrete composites. This compilation includes discussions on often cited seminal publications encompassing experimental mechanics, analytical modeling, the development of test standards, materials characterization and innovations in the science of fiber reinforced concrete (FRC) materials. Collectively, these contributions have greatly improved our insights on how the nano- and micro-mechanics of such composites and processing techniques affect the macroscopic performance of creatively engineered reinforced cement composites. Starting with his Ph.D. the first contribution to understanding the inelastic behavior and fracture of concrete, the …


Transforming Agricultural Residues Into High-Performance Scms Through Mechanochemical Activation, Dia Brown, Juan Pablo Gevaudan Sep 2025

Transforming Agricultural Residues Into High-Performance Scms Through Mechanochemical Activation, Dia Brown, Juan Pablo Gevaudan

C3 Symposium 2025

Despite the abundance of ashed agricultural residues and their potential as supplementary cementitious materials (SCMs), given a high silica content (up to 90 wt.%), their high water demand limits their use. This challenge compromises both the fresh-state workability and mechanical performance of supplemented concrete – a pivotal challenge for countries in the Global South with large agricultural sectors and low production of other industrial SCMs. To address this limitation, we investigate two innovative mechanochemical methods and their effects on the fresh-state workability issues of these ash-based SCMs. This presentation will share our latest results describing how the mechanochemical activation of …


Thermochemical Pre-Treatments On Corn Stover Ash To Boost Its Reactivity, P V P Moorthi, Zhihui Sun Sep 2025

Thermochemical Pre-Treatments On Corn Stover Ash To Boost Its Reactivity, P V P Moorthi, Zhihui Sun

C3 Symposium 2025

When treated properly, corn stover ash (CSA) is known to be an effective source of supplementary cementitious materials (SCM) for use in concrete. The influence of thermochemical pre-treatments on the reactivity of CSA was studied in this project. The result shows that acid pre-treatment was effective and necessary in the removal of organic and inorganic compounds from the corn stover. The pre-treatment conditions including type and concentration of acid used, temperature, pre-treatment duration, and the acid/ash (A/A) ratio are important factors that affect the reactivity of the final product. This study shows that a proper pre-treatment condition will lead to …


Evaluation On Basic Properties And Surface Quality Of Pca Members Using Scallop Shell Sand Concrete With Blue Carbon Fixation, Nene Uesugi, Masaki Tamura, Tetsuya Sasaki, Takashi Saito, Ryota Ozeki, Taichi Yamamoto, Ayano Koseki Sep 2025

Evaluation On Basic Properties And Surface Quality Of Pca Members Using Scallop Shell Sand Concrete With Blue Carbon Fixation, Nene Uesugi, Masaki Tamura, Tetsuya Sasaki, Takashi Saito, Ryota Ozeki, Taichi Yamamoto, Ayano Koseki

C3 Symposium 2025

With carbon neutrality gaining importance as one of the measures against global warming, the building industry is focusing on the development of environmentally friendly building materials to help realize a sustainable society. Japan has the second longest coastline in the world, and its fisheries industry along the coast is well developed and fisheries resources are considered important. In Hokkaido in particular, approximately 400,000 tons of scallops are landed annually, with approximately 110,000 tons of shells becoming waste. In order to make effective use of these discarded and unused resources, the development of blue carbon concrete components, in which scallop shells …


Advancing Characterization Of Cementitious Systems Via Raman Imaging, Chirayu Kothari, Sudharsan R. Kumar, Yaman Garg, Nishant Garg Sep 2025

Advancing Characterization Of Cementitious Systems Via Raman Imaging, Chirayu Kothari, Sudharsan R. Kumar, Yaman Garg, Nishant Garg

C3 Symposium 2025

The drive for sustainability within the cement industry has resulted in the formulation of complex low-carbon cements that show considerable variation in their mineralogical phases, chemical compositions, and particle sizes. These differences can impact the workability, strength, and durability of concrete. Accurately characterizing these properties is challenging and requires a combination of techniques such as microscopy, spectroscopy, and diffraction. Raman imaging is particularly valuable for investigating the entire lifecycle of cement, covering everything from anhydrous cements to hydration and long-term durability. Here, we present its capability to analyze the phase composition of Ordinary Portland Cement (OPC) and Calcium Sulfoaluminate (CSA) …