Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 5701 - 5730 of 31416

Full-Text Articles in Entire DC Network

Stabilized Weak-Gradient Discontinuous Finite Elements With Optimal Error Estimates For Second-Order Elliptic Pdes, Aymen Laadhari Sep 2025

Stabilized Weak-Gradient Discontinuous Finite Elements With Optimal Error Estimates For Second-Order Elliptic Pdes, Aymen Laadhari

Mathematical Modelling and Numerical Simulation with Applications

This work introduces an accurate finite element approach employing a new stabilized discrete weak gradient, designed for second-order elliptic problems on arbitrary conforming meshes. We formulate the approach within a discontinuous Galerkin framework and derive a consistent and coercive bilinear form. Appropriate error analysis on a model problem confirms optimal convergence. Building on the core analysis, we extend the method to more challenging settings, including time-dependent heterogeneous scenarios and a biophysically realistic optimal-control model of photobleaching in the budding yeast cell. We further illustrate the versatility of the weak-gradient construction by applying it to an unsteady level-set equation relevant to …


High-Order Adaptive Solutions For Coupled Fractional Riccati Equations Via Daubechies Redundant Frames, Mutaz Mohammad, Alexander Trounev Sep 2025

High-Order Adaptive Solutions For Coupled Fractional Riccati Equations Via Daubechies Redundant Frames, Mutaz Mohammad, Alexander Trounev

Mathematical Modelling and Numerical Simulation with Applications

Coupled fractional Riccati equations play a fundamental role in modeling complex systems with memory effects and anomalous diffusion, frequently arising in engineering, control theory, finance, and quantum mechanics. Their analytical and numerical treatment remains highly challenging due to the nonlocal nature of fractional-order derivatives and the presence of nonlinear coupling terms. This study introduces an adaptive numerical framework that combines the Caputo fractional derivative with redundant Daubechies wavelet frames. The method leverages multi-resolution analysis, compact support, and controlled redundancy to achieve accurate approximation of both localized and global solution features, particularly in scenarios characterized by singular behavior and long-range memory …


Cold-Shock Protein Scaffold For Engineering Non-Antibody Binding Proteins, Jack Mathew Webster Sep 2025

Cold-Shock Protein Scaffold For Engineering Non-Antibody Binding Proteins, Jack Mathew Webster

USF Patents

Disclosed herein are compositions and methods directed to non-antibody protein scaffolds derived from cold-shock proteins.


Diazotime: A Metabolically-Resolved Reference Database Of Nitrogen-Fixing Microbial Genomes, Julian Damashek, Cody S. Sheik, Caitlin Petro, Christian F. Reeder, Subhadeep Chowdhury, Benjamin J. Kramer, Stephen E. Devilbiss, Juan J. Pierella Karlusich, Jane C. Marks, Patricia M. Valdespino-Castillo, Paula C. Furey, Megan E. Berberich, Amy M. Marcarelli, J Thad Scott, Robinson W. Fulweiler Sep 2025

Diazotime: A Metabolically-Resolved Reference Database Of Nitrogen-Fixing Microbial Genomes, Julian Damashek, Cody S. Sheik, Caitlin Petro, Christian F. Reeder, Subhadeep Chowdhury, Benjamin J. Kramer, Stephen E. Devilbiss, Juan J. Pierella Karlusich, Jane C. Marks, Patricia M. Valdespino-Castillo, Paula C. Furey, Megan E. Berberich, Amy M. Marcarelli, J Thad Scott, Robinson W. Fulweiler

Michigan Tech Publications

Microbial nitrogen fixation (diazotrophy) is a critical ecological process. We curated DiazoTIME (Diazotroph Taxonomic Identity and MEtabolism), a comprehensive database of diazotroph genomes including taxonomic annotation and metabolic prediction. DiazoTIME is unique among databases for classifying diazotrophs because it resolves both taxonomy and metabolic functionality.


Quality Improvement Project Improve Staff Knowledge On Spravato For Treatment Resistant Depression, Cynthia Barraza Guerra Sep 2025

Quality Improvement Project Improve Staff Knowledge On Spravato For Treatment Resistant Depression, Cynthia Barraza Guerra

Doctor of Nursing Practice Projects

Treatment-resistant depression (TRD), defined as major depressive disorder unresponsive to at least two adequate antidepressant trials, is linked to higher morbidity, diminished quality of life, and increased healthcare utilization. Spravato (intranasal esketamine), approved by the U.S. Food and Drug Administration, provides a novel mechanism of action through N-methyl-D-aspartate (NMDA) receptor modulation but requires strict safety oversight due to risks including dissociation and hypertension. This Doctor of Nursing Practice (DNP) quality improvement (QI) project evaluated whether a targeted educational intervention improved staff knowledge and confidence in Spravato safety protocols. Guided by Lewin’s Change Theory, Bandura’s Social Learning Theory, and implemented with …


The Impact Of Hot And Arid Conditions On Dehydration Levels, Some Physiological Variables, And The Performance Some Of Basic Basketball Skills, Ahmed Hassan Yas, Fatmah Abd-Alredah Hatam Sep 2025

The Impact Of Hot And Arid Conditions On Dehydration Levels, Some Physiological Variables, And The Performance Some Of Basic Basketball Skills, Ahmed Hassan Yas, Fatmah Abd-Alredah Hatam

Modern Sport

The atmosphere in Baghdad and most regions of Iraq during the summer is characterized by extreme heat and aridity. These climatic conditions are among the negative factors that significantly impact cognitive function and the performance of athletic skills.

Consequently, The current study was designed to investigate the impact of hot and arid conditions on dehydration levels, specific physiological indicators, and the performance of key basketball skills among first-stage students at Al-Mustansiriya University. A sample of 30 students was randomly divided into a control group and an experimental group. The control group was permitted to consume water and fluids ad libitum …


Compressibility Behavior On Stabilised Peat Soil: A Review, Khairun Najihah Kamarudin, Nurmunira Muhammad, Duraisamy Youventharan Sep 2025

Compressibility Behavior On Stabilised Peat Soil: A Review, Khairun Najihah Kamarudin, Nurmunira Muhammad, Duraisamy Youventharan

Platform: A Journal of Engineering (PAJE)

Peat soil is problematic in geotechnical engineering due to its high compressibility, low shear strength, and low bearing capacity, making it prone to settling under loads. Effective soil treatment is essential, as traditional removal and replacement methods are unsustainable. This review evaluates the compressibility behaviour of peat stabilised with various stabilising agents, including the conventional and non-conventional additives. Soil stabilisation using chemical additives, including cement, lime, fly ash, gypsum, and recycled concrete aggregate (RCA), is widely applied. However, non-conventional additives alone are often less effective in stabilising peat. For example, peat treated with fly ash shows a behaviour similar to …


Multiomics Analysis Of Skeletal Muscle Identifies Dysregulation Of Hypoxia-Induced Genes In Peripheral Artery Disease, Ahmed Ismaeel, Emma Fletcher, Evlampia Papoutsi, Nicholas T. Thomas, William T. Bohannon, Iraklis I. Pipinos, Yuan Wen, Dimitrios Miserlis, Panagiotis Koutakis Sep 2025

Multiomics Analysis Of Skeletal Muscle Identifies Dysregulation Of Hypoxia-Induced Genes In Peripheral Artery Disease, Ahmed Ismaeel, Emma Fletcher, Evlampia Papoutsi, Nicholas T. Thomas, William T. Bohannon, Iraklis I. Pipinos, Yuan Wen, Dimitrios Miserlis, Panagiotis Koutakis

Physiology Faculty Publications

BACKGROUND: Epigenetic modifications such as DNA methylation play a critical role in hypoxic cell programs. However, no previous studies have investigated the epigenetic regulation of gene expression in peripheral artery disease (PAD), a condition characterized by intermittent ischemia. Our study aims to examine how PAD affects the DNA methylome in skeletal muscle of patients with PAD with intermittent claudication or critical limb ischemia compared with non-PAD controls. METHODS: This was a cross-sectional study evaluating differences in the DNA methylome and transcriptome using reduced representation bisulfite sequencing, and small and bulk RNA sequencing, in skeletal muscle from non-PAD controls, intermittent claudication, …


Global Stability And Bifurcation Analysis Of A Predator-Prey Model Involving Allee Effect And Monod-Haldane Functional Response, Resmawan Resmawan, Agus Suryanto, Isnani Darti, Hasan S. Panigoro Sep 2025

Global Stability And Bifurcation Analysis Of A Predator-Prey Model Involving Allee Effect And Monod-Haldane Functional Response, Resmawan Resmawan, Agus Suryanto, Isnani Darti, Hasan S. Panigoro

Mathematical Modelling and Numerical Simulation with Applications

In this paper, the complexity of the dynamic behavior of the interaction between prey and predator is studied. The predator-prey relationship involves Allee effects and Monod-Haldane functional response. The constructed model has been shown to have validity in several respects, including the existence and uniqueness of the solution, as well as its non-negativity and boundedness. Three equilibrium points, namely trivial, axial, and coexistence points, are found, including their global dynamics using the Lyapunov function together with the LaSalle's invariance principle. The effect of the predation conversion rate causes changes in the dynamic behavior of predators and prey, which is characterized …


Solution Of Fractional Order Diffusion Equations With Clique Neural Network, Merve Zeynep Kaya, Mesut Karabacak, Ercan Çelik Sep 2025

Solution Of Fractional Order Diffusion Equations With Clique Neural Network, Merve Zeynep Kaya, Mesut Karabacak, Ercan Çelik

Mathematical Modelling and Numerical Simulation with Applications

In this paper, the clique artificial neural network method is used to solve the fractional diffusion equation, which is a subclass of partial differential equations. The clique neural network architecture is constructed using input, hidden, and output layers. Several degrees of clique polynomials were used as activation functions, and the output layer was obtained by multiplying them with weight coefficients. Subsequently, the optimization equation was derived, and the exact solution, numerical solution, and error function graphs were obtained using a specialized algorithm. Analysis of the results demonstrates that the clique artificial neural network method provides quicker and more accurate results …


Synergistic Modeling Of Hydrogel Gelation Via Time-Delay Dynamics And Machine Learning Algorithms, Mine Babaoglu, Dipesh ., Pankaj Kumar, Jagjit Singh Dhatterwal, Mansoor Alsulami Sep 2025

Synergistic Modeling Of Hydrogel Gelation Via Time-Delay Dynamics And Machine Learning Algorithms, Mine Babaoglu, Dipesh ., Pankaj Kumar, Jagjit Singh Dhatterwal, Mansoor Alsulami

Mathematical Modelling and Numerical Simulation with Applications

This paper presents an integrated framework in which delay differential equation (DDE) modeling and machine learning (ML) approaches are coupled to study hydrogel formation kinetics, with emphasis on delayed crosslinker addition. Conventional mechanistic models disclose many physical and kinetic complexities of reacting mixtures; they seldom depict the nonlinear and time-evolving complexities inherent in developing polymer networks. To address this, a mathematical model is developed that examines how the insertion of crosslinkers affects system stability and equilibrium. Analytical and numerical results show that delays nearing critical levels cause bifurcation behavior with substantial implications on gelation kinetics. Sophisticated machine learning systems, including …


Dynamics And Optimal Intervention Strategies In A Shigellosis Transmission Model, Mehmet Gümüs, Shewafera Wondimagegnhu Teklu, Kemal Türk Sep 2025

Dynamics And Optimal Intervention Strategies In A Shigellosis Transmission Model, Mehmet Gümüs, Shewafera Wondimagegnhu Teklu, Kemal Türk

Mathematical Modelling and Numerical Simulation with Applications

This research explores how water treatment contributes to limiting the transmission of Shigellosis, an infection caused by bacteria from the Shigella genus. A mathematical framework is formulated to evaluate the influence of protective strategies and water purification on the spread of the disease. To confirm the model's biological relevance, its well-posedness is investigated. The basic reproduction number $(\mathfrak{R}_0)$, a critical indicator of disease behavior, is derived using the matrix operator method. Findings indicate that if $\mathfrak{R}_01$, the infection persists, with the endemic equilibrium exhibiting local asymptotic stability. A comprehensive cost-effectiveness analysis reveals that combining environmental protection with water treatment represents …


Htlv-1 And Atll: Epidemiology, Oncogenesis, And Opportunities For Community-Informed Research In The United States, Adrian D. Altieri, Sean P. Reilly, Abu Mansalay, Alan Khoo, Nettie Johnson, Zafar K. Khan, Amy Leader, Pooja Jain, Pierluigi Porcu Sep 2025

Htlv-1 And Atll: Epidemiology, Oncogenesis, And Opportunities For Community-Informed Research In The United States, Adrian D. Altieri, Sean P. Reilly, Abu Mansalay, Alan Khoo, Nettie Johnson, Zafar K. Khan, Amy Leader, Pooja Jain, Pierluigi Porcu

Kimmel Cancer Center Faculty Papers

Human T-cell leukemia virus type 1 (HTLV-1), the first oncogenic human retrovirus, causes adult T-cell leukemia/lymphoma (ATLL), an aggressive neoplasm of mature CD4+ T-cells that is incurable in most patients and is associated with a median survival of less than 1 year. HTLV-1 also causes inflammatory disorders, including HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and uveitis. The estimated lifetime risks of ATLL and HAM/TSP in HTLV-1 carriers are 3-5% and 0.25-1.8%, respectively. Although there is uncertainty about other health effects of HTLV-1, a recent meta-analysis showed an association between HTLV-1 and cardiovascular, cerebrovascular, and metabolic diseases and a 57% increased risk …


Ketorolac Use Following Operative Clavicle Fracture Fixation Is Not Associated With Increased Nonunion Or Surgical Complications: A Propensity-Matched Analysis, Tuckerman Jones, Tej Joshi, Akhil Katakam, Daniella Ogilvie, Sefy Paulose, Balazs Galdi Sep 2025

Ketorolac Use Following Operative Clavicle Fracture Fixation Is Not Associated With Increased Nonunion Or Surgical Complications: A Propensity-Matched Analysis, Tuckerman Jones, Tej Joshi, Akhil Katakam, Daniella Ogilvie, Sefy Paulose, Balazs Galdi

Wills Eye Hospital Papers

OBJECTIVES: Nonsteroidal anti-inflammatory drugs (NSAIDs), including ketorolac, are commonly used for postoperative pain management. Concerns about their potential impact on bone healing have been raised. This study investigated the relationship between ketorolac use and postoperative complications following clavicle surgery, including nonunion rates.

METHODS: This retrospective cohort study used the TriNetX Research Database to identify patients who underwent surgical fixation of clavicle fractures between 2002 and 2022. Two propensity-matched cohorts were created: patients who received postoperative ketorolac and those who did not. Primary outcomes included nonunion diagnosis and revision surgery; secondary outcomes included opioid use, wound disruption, surgical site infection, and …


Application Of Dematel Based On Bipolar Neutrosophic Sets For Sustainable Agriculture Practices, Lazim Abdullah, Nor Liyana Amalini Binti Mohd Kamal Sep 2025

Application Of Dematel Based On Bipolar Neutrosophic Sets For Sustainable Agriculture Practices, Lazim Abdullah, Nor Liyana Amalini Binti Mohd Kamal

Neutrosophic Systems with Applications

The development of natural capital is a fundamental objective within sustainable agricultural systems, where the optimization of both crop and livestock production is vital to addressing global food demands. Despite this imperative, major agricultural sectors such as paddy and rubber production, often fall short of satisfying consumption needs. This study aims to identify and prioritize the most influential criteria for sustainable agriculture using the Bipolar Neutrosophic Set-based Decision-Making Trial and Evaluation Laboratory (BNS-DEMATEL) method. Expert evaluations were elicited from five agricultural specialists using linguistic assessments to analyze the performance and interdependencies among sustainability criteria. Computational analyses were conducted using MATLAB …


The Lived Experiences Of Mothers Facing Phubbing From Their Adolescent Children, Mye Alexis Sep 2025

The Lived Experiences Of Mothers Facing Phubbing From Their Adolescent Children, Mye Alexis

Walden Dissertations and Doctoral Studies

Widespread use of technology, particularly smartphones, introduced new challenges involving parent–adolescent attachment. Although existing literature primarily examines parental phubbing of adolescents, there is a significant gap in research exploring the experiences of mothers who are phubbed by their adolescent children. To address this gap, the central research question guiding this study was: What are the lived experiences of mothers who have been phubbed by their adolescent (ages 14-18) children? Grounded in Bowlby’s attachment theory, this phenomenological qualitative study aimed to deepen understanding of the emotional impacts of phubbing on mothers’ emotional wellbeing, emotional bonding, and mother–adolescent attachment. A homogeneous convenience …


Review On Exploring The Potential Of Black Soldier Fly (Hermetia Illucens) As A Novel Feed Ingredient For Poultry, Muhammad Naeem Jan, Nasir Rajput, Muhammad Naeem, Sher Ali, Ghulam Shabir Barham, Tehseen Fatima Miano Sep 2025

Review On Exploring The Potential Of Black Soldier Fly (Hermetia Illucens) As A Novel Feed Ingredient For Poultry, Muhammad Naeem Jan, Nasir Rajput, Muhammad Naeem, Sher Ali, Ghulam Shabir Barham, Tehseen Fatima Miano

Journal of Bioresource Management

Poultry provides both direct and indirect employment opportunities to individuals. Every farm owner desires a reduced investment with more earnings. Over 50 % of the overall cost of chicken rearing is allocated to feed stuff. Among all feed ingredients, protein sources are the most expensive, yet protein is essential for production and growth. This exorbitant price cannot be sustained by the small-scale farmers. Consequently, contemporary scientists are attempting to substitute the protein supply with black soldier fly in their formulations. This review study examines the advantageous effect of utilizing Black Soldier Fly powder, larvae or oil, as demonstrated in scientific …


Queering The Classrooms: Filipino Teachers’ Perspectives And Practices Of Queer Pedagogy, Holden Kenneth G. Alcazaren, Jonalou S. Labor Sep 2025

Queering The Classrooms: Filipino Teachers’ Perspectives And Practices Of Queer Pedagogy, Holden Kenneth G. Alcazaren, Jonalou S. Labor

Asia-Pacific Social Science Review

With the increasing progress of queer perspectives in the academic setting, there have been calls for LGBTQ+-inclusive teaching practices. In the Philippines, attempts have been implemented to produce curricula and materials that are more gender-responsive and gender-sensitive. However, these initiatives are without their barriers as conservative traditions and sexist ideologies still affect the eradication of gender-based discrimination in the classrooms. To fully grasp these issues, the present study aimed to elicit insights from queer Filipino teachers about their views and perspectives on using queer pedagogy in their classrooms. With these pedagogical choices, the study tried to understand the queering process …


Understanding Cardiovascular Risk: Insights From Coastal Communities In Southeast Sulawesi, Syahrianti Syahrianti, Lilin Rosyanti, Reni Revianti Usman, Ismail Ismail, Agus Bintara Birawida, Sumarheni Sumarheni, Muhammad Fahmi Aziz Sep 2025

Understanding Cardiovascular Risk: Insights From Coastal Communities In Southeast Sulawesi, Syahrianti Syahrianti, Lilin Rosyanti, Reni Revianti Usman, Ismail Ismail, Agus Bintara Birawida, Sumarheni Sumarheni, Muhammad Fahmi Aziz

Media Kesehatan Masyarakat Indonesia

Cardiovascular Disease (CVD) remains the leading cause of death worldwide, with a greater impact on low- and middle-income countries, particularly coastal communities that depend on fragile ecosystems. This study explores the effects of sociodemographic, behavioral, and metabolic factors on CVD incidence among the coastal population of Soropia, Konawe, Southeast Sulawesi. This research employs a quantitative approach with a cross-sectional design and applies Structural Equation Modeling (SEM) using Smart PLS software. Data collection was conducted through standardized questionnaires and physical examinations. The findings reveal that age significantly reduces CVD risk (p = 0.043, Exp(B) = 0.378), while gender and occupation show …


Diversity Of Butterflies (Lepidoptera) In Kanju, District Swat, Khyber Pakhtunkhwa, Pakistan, Said Miraj Ud Din, Khushbakht Asad, Hamid Ur Rahman, Attiya Iqbal Sep 2025

Diversity Of Butterflies (Lepidoptera) In Kanju, District Swat, Khyber Pakhtunkhwa, Pakistan, Said Miraj Ud Din, Khushbakht Asad, Hamid Ur Rahman, Attiya Iqbal

Journal of Bioresource Management

Butterflies are one of the most beautiful creatures on earth. They belong to the phylum Arthropoda, class Insecta, and order Lepidoptera. Butterflies play an important role in the ecosystem, contributing significantly to pollen transfer. They play an important role in pollination, and their foraging behavior enhances the genetic diversity. Additionally, they also play an important role in the food chain and serve as prey for birds, reptiles, and other insectivore organisms. The current study was conducted to find out the diversity and distribution of butterflies in Kanju district Swat, Khyber Pakhtunkhwa, Pakistan. A total 203 specimens were collected from August …


A Review On The Ethnozoological Remedies With The Help Of Animal Body Parts And Its Impact On Their Conservation Status, Minahal Fatima, Bushra Nisar Khan, Mudasser Hasan, Amina Tufail, Farhat Batool, Majida Maqbool, Fakhra Nazir Sep 2025

A Review On The Ethnozoological Remedies With The Help Of Animal Body Parts And Its Impact On Their Conservation Status, Minahal Fatima, Bushra Nisar Khan, Mudasser Hasan, Amina Tufail, Farhat Batool, Majida Maqbool, Fakhra Nazir

Journal of Bioresource Management

The use of wildlife in biomedical science has had a long history as it has been used as experimental animals, Sources of unusual physiology, and of bioactive compounds on which life-saving medicines are based. Amphibians are a Source of antimicrobial peptides, analgesic alkaloids, and regeneration. Immune adaptations and venoms of reptiles have produced cardiovascular medications, anti-clotting solutions and diabetes treatment. Birds serve as models of zoonotic diseases and provide immunological tools e.g. IgY antibodies and support embryology and neurobiology. Advanced studies on human disease, vaccines, cancer resistance and hypoxia tolerance have been facilitated by mammals such as rodents, primates, bats, …


Membrane And Electrodialysis Process On Reverse Osmosis Concentrate Treatment And Resource Recovery: A Review, Mei-Zhen Lim, Yeek-Chia Ho, Yuan-Liang Tai Sep 2025

Membrane And Electrodialysis Process On Reverse Osmosis Concentrate Treatment And Resource Recovery: A Review, Mei-Zhen Lim, Yeek-Chia Ho, Yuan-Liang Tai

Platform: A Journal of Engineering (PAJE)

Reverse osmosis (RO) has been increasingly implemented in wastewater treatment facilities due to its effectiveness in producing high-quality effluent suitable for reuse. Nevertheless, the process produces reverse osmosis concentrate (ROC), which presents considerable environmental management challenges. Hence, ROC treatment is becoming a critical aspect of wastewater management due to its high salinity and complex mix of pollutants. Pressure-driven membrane technologies, including microfiltration, ultrafiltration, nanofiltration, and reverse osmosis, offer high removal efficiency but face challenges such as scaling, fouling, and require chemical cleaning to maintain efficiency. Electrically driven processes like electrodialysis (ED) and electrodialysis reversal (EDR) provide alternative solutions with enhanced …


Spartan Daily, September 30, 2025, San Jose State University, School Of Journalism And Mass Communications Sep 2025

Spartan Daily, September 30, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 16


The (4h) Strategy On Emotional Intelligence And Social Interaction And Its Relationship To The Performance Of Sending And Receiving Skills, Zahraa Jawad Ahmed, Luma Sameer Hamoodi Al-Shaikhly Sep 2025

The (4h) Strategy On Emotional Intelligence And Social Interaction And Its Relationship To The Performance Of Sending And Receiving Skills, Zahraa Jawad Ahmed, Luma Sameer Hamoodi Al-Shaikhly

Modern Sport

The research problem lies in the modern use of strategies, including the (4H) strategy and the weak performance of the skills of serving and receiving the serve in volleyball among third-year female students. The researchers have decided to conduct a study. They tried to know the role of each (4H) strategy, emotional intelligence, and social interaction in the performance of the two skills under study. The research aims to know the degree of each of (4H strategy - emotional intelligence- social interaction- serving- receiving the serve) in the research sample, as well as knowing its effect on each of (emotional …


Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo Sep 2025

Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The lymphatic system is critical to the body's immune and circulatory system, and lymphangiogenesis, the development of new lymphatic vessels from pre-existing ones, is a significant process capitalized upon by cancer during tumorigenesis. Decorin is a small leucine-rich proteoglycan which we have previously shown to be anti-tumorigenic and a suppressor of lymphangiogenesis. We have also shown that decorin exercises its anticancer properties through its ability to evoke autophagy. Through a comprehensive and unbiased proteomic analysis, we explored the implications of decorin exposure on protein expression within mouse lymphatic endothelial cells. We discovered that decorin enriches several protein pathways, notably proteasomal …


Hawthorn (Crataegus Spp.): Unlocking Its Potential For Health And Environmental Sustainability – A Comprehensive Review, Abdelhak Maghchiche Sep 2025

Hawthorn (Crataegus Spp.): Unlocking Its Potential For Health And Environmental Sustainability – A Comprehensive Review, Abdelhak Maghchiche

Journal of Bioresource Management

Hawthorn (Crataegus spp.), traditionally regarded as an important medicinal plant and frequently cited in the literature, presents significant potential for sustainable development and medical biotechnology. This review looks at several areas of Hawthorn that can be explored in response to current healthcare and environmental sustainability issues. Bioactive compounds from hawthorn, including active compounds primarily comprised of flavonoids, procyanidins, and triterpenoids, are responsible for potent antioxidant, anti-inflammatory, cardio-protective, and antimicrobial activities, potentially providing a source of potent therapeutic alternatives. Moreover, hawthorn has a well-documented record as a source of cardiovascular benefits to address arterial hypertension, congestive heart failure, and arrhythmias. In …


Contributing To Acari Knowledge: The First Report Of Trombidium Grandissimum From The Soils Of Cholistan Desert, Rahim Yar Khan, Punjab, Pakistan, Muhammad Adnan Bodlah, Alishbah Mohsin, Ayesha Younas, Aleena Kanwal, Imran Bodlah, Yasir Niaz, Shumaila Khan, Shabbir Hussain Sep 2025

Contributing To Acari Knowledge: The First Report Of Trombidium Grandissimum From The Soils Of Cholistan Desert, Rahim Yar Khan, Punjab, Pakistan, Muhammad Adnan Bodlah, Alishbah Mohsin, Ayesha Younas, Aleena Kanwal, Imran Bodlah, Yasir Niaz, Shumaila Khan, Shabbir Hussain

Journal of Bioresource Management

Trombidium grandissimum is also known by names, red velvet mite, real velvet mite, giant red velvet mite and rain bug, belongs to the family Trombidiidae and subclass Acari. Red velvet mite has four life stages: egg, larva, nymph, and adult. Adult red velvet mites were collected from agricultural farm area of Khwaja Fareed University of Engineering & Information Technology. Important taxonomic features were revealed by morphological study, including a body length of around half of an inch, velvety, unridged skin with dense hairs, stalked eyes, and specialized organs on the anterior legs including sensilla and claws. Carotene-induced bright red coloring …


Seroprevalence, Risk Factors, And Diagnostic Accuracy Of Brucellosis In Upper Dir District, Khyber Pakhtunkhwa, Pakistan, Sidra Sanam, Kamran Khan Sep 2025

Seroprevalence, Risk Factors, And Diagnostic Accuracy Of Brucellosis In Upper Dir District, Khyber Pakhtunkhwa, Pakistan, Sidra Sanam, Kamran Khan

Journal of Bioresource Management

Brucellosis is a zoonotic disease caused by the gram-negative, intracellular bacterium Brucella. Although it is endemic in Pakistan, comprehensive data on its prevalence, risk factors, and diagnostic accuracy remain limited. Therefore, this study aimed to assess these parameters in local communities of District Dir Upper, Khyber Pakhtunkhwa, Pakistan. A total of 345 individuals suspected of brucellosis were investigated. Blood samples and structured questionnaires were collected to determine prevalence and identify associated risk factors. Additionally, 50 culture-confirmed positive cases and 50 negative controls were used to evaluate the diagnostic performance of Enzyme-Linked Immunosorbent Assay (ELISA) and Serum Plate Agglutination Test …


Trophic Niche Overlap Between Native And Alien Fish Species: A Challenge For The Aquatic Ecosystems, Rana Manzoor Ahmad, Abdul Majid Khan, Mariya Basharat, Muhammad Rizwan, Neelam Shahzadi, Muhammad Imran Sep 2025

Trophic Niche Overlap Between Native And Alien Fish Species: A Challenge For The Aquatic Ecosystems, Rana Manzoor Ahmad, Abdul Majid Khan, Mariya Basharat, Muhammad Rizwan, Neelam Shahzadi, Muhammad Imran

Journal of Bioresource Management

The different physiological and biological challenges are introduced not only on land but also in aquatic ecosystems due to increasing climatic changes and human needs. One of these challenges is the introduction of invasive alien species to the native freshwater ichthyofauna. These species not only disturb the ecological balance of the native water bodies but can also be a vector for parasitic diseases. The current study is designed to disclose the trophic niche overlap among exotic (Cyprinus carpio and Oreochromis mozambicus) and indigenous fish species (Labeo calbasu and Cirrhinus mrigala) from Head Baloki (Ravi River), Punjab, …


The Phenology Of Nine Native Tree Species In Gera Moist Afromontane Forest, Southwest Ethiopia, Dereje Egeta, Giche Yadesa, Abeje Eshete, Hailu Belay, Urge Charu, Tensay Teshome Sep 2025

The Phenology Of Nine Native Tree Species In Gera Moist Afromontane Forest, Southwest Ethiopia, Dereje Egeta, Giche Yadesa, Abeje Eshete, Hailu Belay, Urge Charu, Tensay Teshome

Journal of Bioresource Management

Phenology is the study of the time series of biological phenomena of plants, such as flowering, fruiting, and leaflessness, related to seasonal change. Ethiopia is rich in vascular plant species. However, the tree phenology of selected species has been less studied. Therefore, the study aimed to document the phenology of nine native tree species in the Gera moist Afromontane forest in southwest Ethiopia. Forty-five mature trees (five of each species) were selected and numbered according to their species. The intensity of flowering and fruiting was assigned to four different classes. PAST software (version 4.03) and Microsoft Excel (version 2016) mapped …