Digital Commons Network^™

The Guardian The Month Of October 2025, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of October 2025. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Escape Of Kdm6a From X Chromosome Is Detrimental To Ischemic Brains Via Irf5 Signaling, Conelius Ngwa, Afzal Misrani, Kanaka Valli Manyam, Yan Xu, Shaohua Qi, Romana Sharmeen, Juneyoung Lee, Long-Jun Wu, Louise Mccullough, Fudong Liu

The Brown Foundation: Institute of Molecular Medicine

The role of chromatin biology and epigenetics in disease progression is gaining increasing recognition. Genes that escape X chromosome inactivation (XCI) can impact neuroinflammation through epigenetic mechanisms. Our previous study has suggested that the X escapee genes Kdm6a and Kdm5c are involved in microglial activation after stroke in aged mice. However, the underlying mechanisms remain unclear. We hypothesized that Kdm6a/5c demethylate H3K27Me3/H3K4Me3 in microglia, respectively, and mediate the transcription of interferon regulatory factor 5 (IRF5) and IRF4, leading to microglial pro-inflammatory responses and exacerbated stroke injury. Aged (17–20 months) Kdm6a/5c microglial conditional knockout (CKO) female mice (one allele of the …

Understanding The Impact Of Transnational Education: Insights From Uk Tne Alumni, Sladana Krstic, Alexander Towne, Liz Worthen

Higher education research

This study explores the impact of UK transnational education (TNE). The research is based on analysis of survey data from 550 UK TNE alumni augmented with interviews of 27 UK TNE graduates. As transnational education (TNE) continues to expand – across borders, institutions, and delivery models—so too does the imperative to understand its impact. This extends not only to students and graduates, but also to the local communities in which TNE is embedded. This is a global study capturing views of individuals who have experienced UK TNE across over 70 countries. The study reveals the substantial impact of UK TNE …

Exploring The Relationships Between Childhood Emotional Neglect, Attachment, Perfectionism, And Adult Mental Health Struggles Across The Socioeconomic Spectrum, Jordan Biedrzycki

Dissertations

This mixed-methods, cross-sectional study investigated the associations between childhood emotional neglect, perfectionism, attachment insecurity, and internalizing symptoms (depression and anxiety) among adults from varying socioeconomic (SES) backgrounds. Participants (N = 210) aged 18 years or older completed five validated self-report instruments for the quantitative analyses and answered two optional open-ended questions that yielded qualitative data. Data from the self-report measures were analyzed using independent samples t-tests, linear regressions, and moderation analyses conducted with the PROCESS macro. Three hypotheses were tested in this study. First, participants from high-SES backgrounds reported experiencing emotional neglect more frequently than other maltreatment subtypes (t = …

Complementary, But Not Equivalent: Clarifying The Role Of Rwe And Rct In Migraine Research, Mario F. P. Peres, Hsiangkuo Yuan, Cristina Tassorelli

Department of Neurology Faculty Papers

No abstract provided.

Necrobiosis Lipoidica Arising In A Port Wine Stain Treated With Topical Ruxolitinib, Neena Edupuganti, Jay Nguyen, Fahad S. Siddiqui, Victoria Dukharan, Rajiv Nathoo

GME Publications

We present a unique case of necrobiosis lipoidica (NL) arising within a port-wine stain (PWS), which, to our knowledge, has not been previously reported. NL is a rare granulomatous disorder often associated with diabetes mellitus, characterized by chronic inflammation and microvascular dysfunction. PWS, a congenital vascular malformation, results from defective endothelial differentiation and capillary malformation. The coexistence of these conditions suggests a potential link in their pathophysiological mechanisms, including inflammation, endothelial dysfunction, and shared signaling pathways such as mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K), and tumor necrosis factor (TNF)-alpha. Our patient's NL lesions demonstrated improvement with topical ruxolitinib, a …

Diabetes-Related Foot Complications And Socioeconomic Influences Among Hispanic Males In South Texas: A Scoping Review, Mariana J. Rodriguez, Demian Rodriguez, Amanda L. Killeen

School of Podiatric Medicine - Student Research

Introduction: Diabetes mellitus is the 7^th leading cause of death in the United States and is 6^th in the state of Texas. Counties from South Texas are primarily affected with higher rates of diabetes than both the state and national average. Diabetes mellitus is a complex and progressive disease which can affect multiple systems of the body, leading to serious complications if untreated, especially in the lower extremities. Uncontrolled diabetes is often associated with diabetic foot ulcers (DFU), foot infections, and lower extremity amputations (LEA). South Texas is a region predominantly populated by Hispanic Americans who are disproportionally …

Manufactured Monstrosity: Analyzing And Challenging The Narrative Of Lgbtq+ Terrorism, Samantha Salter

Colorado Law Student Scholars

No abstract provided.

Wooster Magazine: Annual Report Edition 2024-25, Caitlin Paynich Stanowick

Wooster Magazine: 2021-2030

The fall Annual Report Edition 2024-25 of Wooster magazine highlights a year of meaningful progress and shared achievement across campus. The annual financial review reports on the College’s operating revenues and expenses and showcases the ways donors contributed to the ongoing success of Wooster and its students in the past year. New endowments honoring beloved professors Ralph Bangham of biology and Nancy Ditmer of music are highlighted. Members of the Class of 2025 share their new paths in graduate study, research, and fulfilling careers. Wooster’s new minors in climate studies and humanities, arts and creative computing broaden curricular opportunities, providing …

Suicide Prevention Through The Reduction Of Counseling Stigma In Fort Riley, Kansas, Yanni Kagiwada-Moya

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Goal Statement: The goal of this social change portfolio is to decrease the stigma of seeking mental help through addressing culture, norms, or systems within Fort Riley, Kansas, that contribute to stigma and suicide risk while using preventative measures to reduce suicide ideation and risk.

Significant Findings: This project focuses on reducing counseling stigma to prevent suicide among military personnel and veterans at Fort Riley, Kansas. Despite available mental health services, 44% of soldiers report fearing career impacts if they seek help, highlighting the need for cultural and systemic change (Irwin Army Community Hospital, 2024). Using the Social- Ecological Model …

Diabetes-Related Foot Complications And Socioeconomic Influences Among Hispanic Males In South Texas: A Scoping Review, Mariana J. Rodriguez, Demian Rodriguez, Amanda Killeen

School of Podiatric Medicine Publications

Introduction: Diabetes mellitus is the 7th leading cause of death in the U.S. and 6th in Texas. South Texas counties have higher diabetes rates than state and national averages. This complex, progressive disease affects multiple body systems and can lead to serious complications, especially in the lower extremities. Uncontrolled diabetes is often associated with diabetic foot ulcers (DFU), foot infections, and lower extremity amputations (LEA). South Texas, predominantly Hispanic American, is disproportionately affected. This demographic faces clinical barriers due to a lack of cultural understanding, highlighting the need for culturally sensitive healthcare workers such as promotoras. This study aimed to …

An Effective And Organized Mentorship Model: Does It Affect The Emerging Leaders’ Call To Ministry And The Longevity Of The Universal Church?, Linda F. Parker

Doctor of Ministry (DMin)

The concept of mentorship is undeniably a fundamental tool for personal and professional growth. Statistics show that mentorship has a vital impact on both individuals and organizations. Could having a strategic mentoring plan in ministry make a meaningful difference for individuals and the Universal Church? This dissertation has explored the effects of mentorship and models based on experiences and strategies from those who identify as ministry leaders. For the Apostle Paul, Christ's life serves as a model and example, as he states, “Follow my example, as I follow Christ” (1 Cor 11:1). These words are the exact phrase that Jesus …

Cul3 Postnatal Homozygous Deletion In Forebrain Results In Behavioral Differences, Prathibha Sekar, Qiang‐Qiang Xia, Alex C. Stokes, Feiyu Quan, Jeffrey Singer, Craig M. Powell

Biology Faculty Publications and Presentations

Large-scale human genetic studies implicate multiple genes that regulate protein ubiquitination in autism spectrum disorder (ASD). De novo loss-of-function mutations in the gene CULLIN3 (CUL3) are implicated in autism and intellectual disability (ID). CUL3 is an essential component of an E3 ubiquitin ligase complex required for ubiquitination of substrates, often a signal for proteasomal degradation. Homozygous deletion of Cul3 is embryonically lethal. Recent studies show heterozygous deletion of Cul3 results in phenotypes with some face validity for autism in constitutive and conditional Cul3 heterozygotes. To understand the function of Cul3 in late postnatal development and function in the brain, we …

(Si15-022) Five Efficient Cryptography Authentication Schemes With Functional Relation On General Spaces, L. Sreenivasulu Reddy, S. Lakshmisri

Applications and Applied Mathematics: An International Journal (AAM)

This work addresses the growing demand for diversification in cryptographic schemes to secure communication. This work proposes a novel suite of algorithms, including two block ciphers (TPBlock and TAP-Block), two stream ciphers (TP-Stream and TAP-Stream), and a zero-knowledge proof scheme (F-zero knowledge proof). All schemes leverage functional relations defined over the real number space with a dimension greater than one for encryption, decryption, and key generation, offering an alternative to the number-theoretical aspects and algebraic structures commonly used in existing schemes. The main goal of this work is to introduce and propose these five novel cryptographic schemes to provide authentication …

(Si15-010) On Perturbations Of Gabor Frames, Jamkhongam Touthang

Applications and Applied Mathematics: An International Journal (AAM)

Stability plays a crucial role in frame theory and its applications. The present paper studies the interaction between Gabor frames and perturbations, presenting perturbation results related to small changes of the frame parameters and the window functions both in regular and irregular settings. Examples are provided for illustration. Additionally, the paper briefly discusses algorithms pertinent to Gabor frames under perturbations and highlights challenging areas in the field.

(Si15-121) Analyzing Seitr Tuberculosis Transmission Model Using Caputo–Fabrizio Fractional Derivative With Diverse Contact Rates, S. S. Sumaiya Banu, T. Gunasekar, S. Manikandan, Kamalendra Kumar, M. Suba

Applications and Applied Mathematics: An International Journal (AAM)

In the modern age, tuberculosis remains a pressing global health concern. Our study introduces and evaluates the SEITR pandemic TB transmission model, dividing the population into five compartments to explore distinct characteristics relevant to our investigation. Additionally, we delve into the application of fractional calculus. Through the Laplace transform method, we derive series solutions for all compartments, ensuring their existence and uniqueness. We also investigate the reproduction number of the tuberculosis epidemic model, examining how varying contact rates impact disease spread. We apply the predictor-corrector method for the Caputo-Fabrizio fractional derivative to verify the accuracy of our approach. This accurately …

(Si15-120) Exploring Fractional Difference Equations And Their Applications With Mahgoub-Transform, Tharmalingam Gunasekar, Periyasamy Udhayasankar, Prabakaran Raghavendran, Kamalendra Kumar

Applications and Applied Mathematics: An International Journal (AAM)

We discuss the introduction and study of the nabla discrete Mahgoub transform along with its defining properties. The transform of fractional sums and fractional differences are derived, demonstrating the applicability of the transform from the computational viewpoint. Employing the transform, fractional difference equations with initial value problems are solved, thereby enhancing the knowledge of their closed forms. As a side-effect of the Mahgoub-transforms, an attractive connection is established, showing that the discrete Mittag-Leffler function acts as the eigenfunction for the Caputo-type fractional difference operator nabla. These results strengthen the core basis for fractional calculus and herald industrial applications in various …

Extraterritoriality In Ai: Harmonizing The Digital Market Act And Us Antitrust Law, Daniel Goicouria

Vanderbilt Journal of Transnational Law

No abstract provided.

Arcadia Magazine, 2025-10

Alumni Magazine

No abstract provided.

Une Com Research And Scholarship Fall Forum October 2025, Une Com Research & Scholarship

Osteopathic Student Research Symposia

Program including abstracts from the University of New England College of Osteopathic Medicine’s 2025 Research and Scholarship Fall Forum.

Supplemental content: List of award winners.

Population Genomics And Status Of The Flattened Musk Turtle (Sternotherus Depressus) In The Locust Fork Of The Black Warrior River, Seamus C. O'Brien

Theses

Alabama is home to some of the highest freshwater endemism in the world and ranks near the top in numbers of endangered and extinct species. One of these endangered species is the Flattened Musk Turtle (FMT), only found in the Black Warrior River Drainage of Alabama above the Fall Line. The FMT is listed as “Threatened” by the United State Fish and Wildlife Service under the Endangered Species Act and is considered Critically Endangered by the International Union for the Conservation of Nature due to drastic declines in populations since the 1980s. Declines have been attributed to several factors, including …

Assessing Expected Cover Of Invasive Flora Species Near Corridor Features By Distance, Joshua G. Logan

Theses

Fragmentation of landscapes has been a growing topic of interest within scientific literature over the past several decades, as the way we as humans affect our planet becomes more apparent as the years go on. As humans, we have shaped the land and what it contains in immeasurable ways, erasing or forever altering entire natural ecosystems. Chief among the drivers altering these ecosystems is the fragmentation of landscapes, which can have all kinds of effects on natural ecosystems, from limiting nutrient transport to providing easier access for invasives to permeate throughout a landscape. Corridors are significant areas of interest regarding …

Independent- October 2025, Leslie Lozada

The Independent (1988-present)

No abstract provided.

Alfred Russel Wallace Notes 38. Alfred Russel Wallace's "Revolt Of Democracy": A Critical Analysis Of Early 20th Century Labor Theory And Its Contemporary Relevance, James Williams, Charles H. Smith Editor

Faculty/Staff Personal Papers

This article examines Alfred Russel Wallace’s political treatise The Revolt of Democracy (1913), analyzing his theoretical framework for addressing labor unrest and economic inequality in early 20th-century Britain. Wallace's work presents a comprehensive critique of competitive capitalism and proposes systematic government intervention to address structural poverty. Through close textual analysis and comparison with contemporary UK labor conditions, this study evaluates the enduring relevance of Wallace's economic theories and policy prescriptions. The analysis reveals significant continuities between early 20th-century and contemporary debates about living wages, government employment standards, and wealth redistribution, while highlighting both the prescience and limitations of Wallace’s analytical …

Columns Fall 2025, Southern Adventist University

Alumni Newsletter

The Fall 2025 issue of Columns features articles about Southern's inaugural Bachelor of Science in Engineering graduates, Homecoming Weekend 2025, notes from God in nature, and service opportunities.

Bone Mineral Density Of Willow Ptarmigan (Lagopus Lagopus) As A Potential Taphonomic Factor In Skeletal Part Attrition, Frank J. Dirrigl Jr., Samuel R. Buchanan

School of Integrative Biological & Chemical Sciences Faculty Publications

Agents of taphonomy can bias skeletal parts and the frequency of bones in archaeological sites. An important factor to consider is the possible effect of bone density-mediated attrition on archaeornithological assemblages. We scanned willow ptarmigan (Lagopus lagopus) specimens using a Lunar iDXA and an enCcore small animal body add-on to develop a rank-order scheme based on the volumetric bone mineral density (vBMD) of skeletal parts. Our results identified the tibiotarsus and femur to be the least dense bones, while carpometacarpus, 3rd digit, and coracoid were the densest. This novel scheme allowed us to evaluate a sample of 22 …

Oceanographic Drivers Of Recruitment And Reproductive Potential Of Gopher Rockfish (Sebastes Carnatus) – Historical Variability And Future Projections Under Climate Change, Madison Sandquist

Capstone Projects and Master's Theses

Anticipating climate-change impacts on fisheries requires understanding how marine species respond to future ocean conditions. The productivity and abundance of fish populations are largely shaped by the survival of early life stages, which are highly sensitive to ocean conditions. Variation in ocean conditions can influence early stages of fish species by influencing reproductive output of adults and/or larval health, survival, and retention. The goal of this study was to understand how oceanographic variables can impact reproduction and recruitment of a nearshore rockfish species, gopher rockfish (Sebastes carnatus), helping to forecast potential climate change impacts on the population. I assessed historical …

Combating Obesity: Creating A Comprehensive Wellness Plan For Uninsured & Low-Income Populations, Kayla C. Berrios

Doctor of Nursing Practice Scholarly Projects

Aim: The aim of this project was to research the specific barriers encountered by obese patients that are low-income and uninsured. The goal of this data collection was to inform the stakeholders involved in creating a comprehensive wellness plan for obese patients.

Background: The staff at Good Neighbor Clinic have struggled to support their support their obese patients with weight reduction. Many of the ailments that patients seek care for correlate to their obesity. Health promotion in this community clinic needs a more comprehensive program to support patients during their weight loss experience, providing support and resources to allow for …

Prenatal Exposure To Domestic Violence And Its Impact On Infant Stress-Response Development, Erica Cooper

Expo Student Presentations

2025 Fall Expo Online Poster Presentation

• Health Sciences & Health Professions
• Social & Behavioral Sciences

Reduction And Prevention Of Intimate Partner Violence In King County, Wa, Leta Whitney

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Goal Statement: The goal of my social change project is to reduce and prevent intimate partner violence in King County, WA, through educational awareness, training, and supportive resources for victims and perpetrators, as well as the communities in which they reside. Significant Findings: Intimate Partner Violence (IPV) is a preventable public health issue that affects millions of Americans and their communities, and it can occur across an entire lifespan. The National Intimate Partner and Sexual Violence Survey (NISVS) suggests that an estimated 8.5 million women and 4 million men in the United States have reported experiencing a level of IPV …