Digital Commons Network^™

Cv: Christina Jeslis (Nursing), Christina Jeslis

Nursing Department Faculty Curricula Vitae

No abstract provided.

Bluefish (Pomatomus Saltatrix) Neurocranium, Courtney R. Schober, Alyssa Olmeda, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Monotone Positive Solutions Of Impulsive Differential Equations Asymptotic To Nonprincipal Solutions, Si̇bel Doğru Akgöl, Ağacik Zafer

Turkish Journal of Mathematics

This study investigates the asymptotic behavior of monotone positive solutions for a general class of nonlinear second-order impulsive differential equations. By employing the principal and nonprincipal solutions of the associated homogeneous equation, we establish the existence of a monotone positive solution asymptotic to a nonprincipal solution at infinity. To achieve this, we also prove a compactness criterion for an effective use of Schauder’s fixed-point theorem. Under suitable conditions, similarly to the classical case, it is demonstrated that a monotone positive solution asymptotic to a nonprincipal solution exists. A concrete example is given to illustrate the results.

Daily Eastern News: November 12, 2025, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

Adsorptive Removal Of Arsenite And Cobalt By Commercial Sorbents, Sevda Joudiazar, Sushma Yadav, Zhiming Zhang, Anshuman Satpathy, Eustace Fernando, Roxana Rahmati, Junchul Kim, Rupali Datta, Dibyendu Sarkar

Michigan Tech Publications

Despite the prevalence and toxicity of heavy metals in the environment, arsenic and cobalt are of particular concern due to their high mobility and bioaccumulation potential, particularly in contaminated groundwater. Herein, we studied the adsorption behavior of commercially available sorbents, including Fluorosorb-100 (FS-100), Fluorosorb-200 (FS-200), and Filtrasorb-400 (F-400), for the removal of arsenite (As(III)) and cobalt (Co(II)), aiming at the selection of filter media in terms of future groundwater remediation. Kinetic analysis revealed that As(III) adsorption followed a pseudo-second-order model, while Co(II) showed mixed first- and second-order behavior, reflecting sorbent-dependent mechanisms. Equilibrium isotherm modeling revealed strong correlations with both Langmuir …

An Annotated Chromosome-Level Genome For The Red-Fronted Brown Lemur (Eulemur Rufifrons) Sheds Light On Brown Lemur Evolution, Kathryn M. Everson, Andrew N. Black, Mariah E. Donohue, David W. Weisrock

Biology Faculty Publications

The red-fronted brown lemur (Eulemur rufifrons) is an important species to the function of Madagascar’s ecosystems, contributing to critical ecological processes such as seed dispersal. Given its ecological, as well as cultural, importance, genomic resources for E. rufifrons are valuable for understanding evolutionary history and informing conservation strategies. In this study, we present an annotated chromosome-level genome assembly for E. rufifrons, generated using PacBio HiFi long reads and Hi-C proximity ligation data, and demonstrate its utility for understanding patterns of divergence among members of the genus Eulemur. The chromosome-level genome size is 2.41 Gb, and it exhibits high-quality metrics including …

People-Centred Care (3rd Ed.), Registered Nurses' Association Of Ontario

General Submissions: Community and Population-based Materials

This BPG replaces the RNAO BPG Person- and Family-Centred Care (2015) (22), and includes the combination of two other BPGs, Establishing Therapeutic Relationships (2006) (23) and Strengthening and Supporting Families through Expected and Unexpected Life Events (2006) (24). These BPGs were merged because of the overlapping clinical concepts. Additionally, RNAO’s Best Practice Spotlight Organizations® (BPSO®)G provided feedback that merging the three would streamline the implementation and evaluation of the BPGs.

The Association Between Social Determinants Of Health And Pressure Injury Development In Middle-Aged Adult Oncology Patients, Ashley Marston

Electronic Theses and Dissertations Archive

In the United States, pressure injuries are a severe health problem that affect over 2.5 million people while approximately 60,000 of the affected will die annually from complications or infections related to the pressure injury. However, few studies have explored associated factors in the middled-aged adult oncology patient population Social Determinants of Health (SDOH) are known to affect health and well-being; yet there is limited evidence that SDOH directly affect oncology patients and the risk for pressure injuries. This study will explore clinical factors associated with these social determinants of health, as well as several demographic categories such as race, …

2025-11-12 Timeout Session: Caroline Penner Makes Her Mark In Wcc, Julia Pilch

The Spectator Online

No abstract provided.

Implementing Pst In Older Adults Facing Major Surgery: A Randomised Controlled Pilot Study, Victoria Tang, Lejla Pepic, Erika Higuchi, Christina Keny, Elizabeth Macias Lopez, Ezenwa C Onyema, Harleen Sandhu, Veronica Yank, Patrick J Raue

Faculty, Staff and Student Publications

Introduction: Depressive symptoms are common in the growing geriatric surgical population and are associated with important patient-centred surgical outcomes, including postoperative delirium, discharge to postacute care facility and decline in functional status. Few interventions have been developed to address depressive symptoms in the perioperative setting.

Methods and analysis: We designed a feasibility and acceptability study of a nine-session problem-solving therapy (PST) telehealth perioperative intervention aimed at reducing postoperative functional decline and depressive symptoms among at-risk older adults undergoing major surgical procedures. Acceptability will be evaluated using a patient-centred five-question survey, assessing participant satisfaction and perceived usefulness of the perioperative intervention. …

Telemental Health Utility: Working Toward Foster Carer Role Satisfaction And Placement Stability, Carlos David Ortiz

Walden Dissertations and Doctoral Studies

Approximately 400,000 children in the Child Welfare System have an average of more than three placement disruptions while in care in what is termed placement instability (PI). PI is a known toxin to children’s neurodevelopment that predisposes them to a life of poor behavioral outcomes. Previous research shows that foster parents dissatisfied with their carer role contributed to PI by quitting or terminating a child’s placement. However, an important gap remains in the PI literature about the ability of telemental health (TMH) to provide adequate support to foster parents, to increase satisfaction in the carer role and potentially decrease the …

The College Voice, Vol. 62, No. 4 [November 12, 2025], Connecticut College

2025-2026

No abstract provided.

Antibiofilm Potential Of Zanthoxylum Zanthoxyloides Bark-Extract Against Biofilm-Producing Streptococcus Mutans In Dental Caries, Efunwole Omonike Omolade, Olaitan J. Olubukola, Wahab Abideen A, Oyedara Opemipo Omotayo, Oluwajide O. Odunola

Tanzania Journal of Science

Streptococcus mutans is the major cause of dental caries, which is costly to treat. The burden is worse in low- and middle-income countries, due to poor access to oral health services and diets high in free sugars. Conventional antibiofilm agents in oral health often have side effects, prompting the search for safer and affordable alternatives. This study investigates the antibiofilm activity of Zanthoxylum zanthoxyloides bark extract against biofilm-forming S. mutans. Dental plaque and tooth samples were collected from hospitals after ethical approval. S. mutans was identified using standard microbiological methods on Mitis Salivarius agar supplemented with Bacitracin and potassium tellurite. …

Nepenthes Megastoma (Nepenthaceae), A Micro-Endemic Pitcher Plant From Puerto Princesa Subterranean River National Park, Palawan, Philippines, John Charles A. Altomonte, John Paul R. Collantes, Vernaluz Mangussad, Rene Alfred Anton Bustamante, Alastair S. Robinson

Environmental Science Faculty Publications

Nepenthes megastoma is described and illustrated as a new species from the Puerto Princesa Subterranean River National Park, a UNESCO World Heritage Site in Palawan Philippines. This carnivorous tropical pitcher plant is currently known from just three locations in the Mount Saint Paul karst formation, where it grows on vertical limestone walls. Morphologically, N. megastoma is characterised by its highly branched stems, campanulate pitchers, peltate tendril exsertion, dimorphic upper pitchers, and unidirectionally upturned female flowers. It is assessed as Critically Endangered under the IUCN Red List criteria, based on its restriction to three subpopulations comprising few total individuals. Pitcher morphology …

Apoe-Targeted Therapeutics For Alzheimer’S Disease, Hussein N. Yassine, Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory Cole, Julia Tcw, Jan Johansson, Kassandra Kisler, Ornit Chiba-Falek

Physiology Faculty Publications

Apolipoprotein E (APOE) is the major lipid transport protein in the brain. Produced primarily by astrocytes and microglia, it delivers cholesterol and other lipids for membrane repair, synaptic maintenance, and immune regulation. Through interactions with specific lipid receptors, APOE maintains neuronal and vascular health. The APOE ε4 allele (APOE4), carried by approximately one-quarter of the population, has an altered protein conformation, which reduces lipid transport efficiency and modifies receptor binding. These changes disrupt lipid homeostasis, increase risk of chronic unresolved neuroinflammation and vascular inflammation, and cause breakdown of the blood–brain barrier (BBB), thus increasing neuronal vulnerability to disease pathology and …

Threads Of Attachment: Exploring Relationship Development Among Marginalized Populations Of Childhood Sexual Abuse Survivors, Eunique S. Powell

Walden Dissertations and Doctoral Studies

Childhood Sexual Abuse (CSA), traumatic sexual violence within trusted relationships, continues to impact children in the United States and often leads to insecure attachments in adulthood. There was a gap in the literature concerning the experiences of adult survivors of CSA within marginalized communities, where such experiences are frequently ignored. The purpose of this qualitative descriptive phenomenological study was to explore how adult survivors of CSA from marginalized populations develop attachments. Bowlby argued that maintaining mental health in adulthood depends on forming healthy and secure relationships during childhood. Bowlby’s attachment theory served as the framework to understand how early attachment …

Transforming Public Services For Stem Students And Faculty, Tessa Withorn, Robert Detmering

Faculty and Staff Scholarship

Despite institutional priorities to expand STEM education and research activity, some academic libraries struggle to engage faculty and students in these disciplines with library resources and services. This column shares and reflects on how strategic liaison librarianship can address the needs of STEM programs at a large, public university. Implementing new services around research impact and data management and building fruitful connections with STEM researchers has reinvigorated and increased engagement with the library. In the future, a team-based liaison model shows promise for sustaining relationships and forging new paths that communicate the value and impact of the library.

Shade As An Agro-Technique To Improve Gas Exchange, Productivity, Bioactive Potential, And Antioxidant Activity Of Fruits Of Hylocereus Costaricensis, Milena Maria Tomaz De Oliveira, Noemi Tel-Zur, Francisca Gislene Albano-Machado, Daniela Melo Penha, Monique Mourão Pinho, Marlos Bezerra, Maria Raquel Alcântara De Miranda, Carlos Farley Herbster Moura, Ricardo Elesbão Alves, William Natale, Márcio Cleber De Medeiros Corrêa

Plants, Soils, and Climate Faculty Publications

Hylocereus species are promising for enhancing fruit productivity in arid regions, but high solar radiation often leads to yield loss. This study aimed to evaluate the short-term impact of different shading levels on the physiological performance, productivity, and post-harvest quality of Hylocereus costaricensis under semi-arid conditions. Plants were grown in the field under two shade levels, i.e., 35 and 50% and their performances were compared to plants under control, i.e., 0% of shade or full sunlight. The nighttime CO₂ assimilation and productivity increased significantly by 310.5 and 114.6% and 34.3 and 50.14% for plants under 35 and 50% of …

Morphometric And Meristic Analysis Of Labeo Coubie In Esa-Odo Water Reservoir, Esa-Odo, Osun State Nigeria, Olugbemi V. Ekundare, Funmilayo B. Oyekanmi, Mahmud Sanni, Azeez Aransi, Dorcas O. Owolabi

Tanzania Journal of Science

One of the common species of family Cyprinidae found in Nigeria and West Africa is Labeo coubie. They are of commercial importance in West Africa. This study embarked on the assessment of the length- weight relationship, condition factor, morphometrics and meristic characteristics of L. coubie from Esa-Odo water reservoir, Esa-Odo, Osun State Nigeria. A total of 135 (65 males and 70 females) individual L. coubie collected from fishermen were subjected to morphometric and meristic analysis. Results showed 4.90, 5.46 and 5.24 as the b value for male, female and combined sexes respectively, describing positive allometric growth for all the fish …

Phenomenon-Based Learning And Storylines In K-12 Science Education: A Systematic Review Of Current Research, Implementation, And Future Directions, Kate Ireton Walker, Noushin Nouri

Teaching and Learning Faculty Publications

Phenomenon-based learning (PhBL) and storylines represent emerging pedagogical approaches in K-12 science education that emphasize student-centered inquiry and real-world connections, yet comprehensive synthesis of research in this field remains limited. This systematic review synthesizes current literature on PhBL and storyline approaches to identify key themes, implementation practices, and research gaps in K-12 science education. Using PRISMA guidelines, we systematically searched education journals, identifying 24 articles published between 2013 and 2024. Qualitative inductive analysis revealed six major themes through iterative coding and collaborative discussion. Six interconnected themes emerged: (1) Theoretical Foundations encompassing constructivist frameworks and pedagogical principles; (2) Curriculum Design and …

Immunogenomic Diversity Of Triple-Negative Breast Cancers In Obese And Non-Obese Black And White Women, Fokhrul Hossain, Denise Danos, Jovanny Zabaleta, Xiao-Cheng Wu, Luis Del Valle, Chindo Hicks, Jiande Wu, Jerneja Tomsic, Susan Neuhausen, Yuan Chun Ding, Kavitha Mukund, Zahra Mesrizadeh, Shankar Subramaniam, Augusto Ochoa, Victoria Seewaldt, Lucio Miele

School of Medicine Faculty Publications

Racial disparities in incidence and outcomes of triple-negative breast cancer (TNBC) have been attributed to ancestry, socioeconomic factors and/or obesity. We studied 253 TNBCs from 128 Black and 125 White women. Arms were balanced for age, AJCC stage, histological grade and molecular subtypes, and differed significantly in BMI distribution, obesity, and Area Deprivation Index. We examined survival rates, whole-transcriptome RNASeq and genetic ancestry. In our sample, Black race or obesity were not intrinsically predictive of poor outcomes. TNBC molecular portraits varied with stage and biological aggressiveness, irrespective of race. We identified a novel group of TNBCs with a distinctive luminal-like …

Dendritic Inhibition Effects In Memory Retrieval Of A Neuromorphic Microcircuit Model Of The Rat Hippocampus, Nikolaos Andreakos, Vassilis Cutsuridis

School of Engineering, Computing and Mathematics

Background: Studies have shown that input comparison in the hippocampus between the Schaffer collateral (SC) input in apical dendrites and the perforant path (PP) input in the apical tufts dramatically changes the activity of pyramidal cells (PCs). Equally, dendritic inhibition was shown to control PC activity by minimizing the depolarizing signals in their dendritic trees, controlling the synaptic integration time window, and ensuring temporal firing precision. Objectives: We computationally investigated the diverse roles of inhibitory synapses on the PC dendritic arbors of a CA1 microcircuit model in mnemonic retrieval during the co-occurrence of SC and PP inputs. Results: Our study …

Integrating Heritage Assets Into Peatland Restoration: Finding, Assessing And Valuing The Palaeoenvironmental Archive, Heather Davies, Ralph Fyfe

School of Geography, Earth and Environmental Sciences

Peatland restoration projects aim to improve the delivery of ecosystem services. Cultural heritage and Historic Environment assets are usually identified as co-beneficiaries of restoration but are not commonly well-integrated at the planning or design stages. This paper considers the heritage value of upland peatlands and methods for integrating these values in ecosystem services approaches. Taking Exmoor National Park as a case study, an extensive walkover survey identified 119 small mires and assessed their cultural heritage asset potential. Many were not previously recognised as part of the Historic Environment potential of the upland. A novel valuation system based on proximity of …

Phanerozoic Paleoenvironmental And Paleoclimatic Evolution In Svalbard, Aleksandra Smyrak-Sikora, Peter Betlem, Victoria S. Engelschiøn, William J. Foster, Sten Andreas Grundvåg, Mads E. Jelby, Morgan T. Jones, Grace E. Shephard, Kasia K. Śliwińska, Madeleine L. Vickers, Valentin Zuchuat, Lars Eivind Augland, Jan Inge Faleide, Jennifer M. Galloway, William Helland-Hansen, Maria A. Jensen, Erik P. Johannessen, Maayke Koevoets, Denise Kulhanek, Gareth S. Lord, Tereza Mosociova, Snorre Olaussen, Sverre Planke, Gregory D. Price, Lars Stemmerik, Kim Senger

School of Geography, Earth and Environmental Sciences

Sedimentary rocks can provide information about the Earth paleoenvironment and are studied extensively to understand the causes and consequences of global climate changes in deep time. They facilitate long-time perspectives that constrain climate models and provide analogues for how Earth systems may respond to, and recover from, intervals of profound environmental change, including projected anthropogenic change. The Norwegian Svalbard archipelago offers an extensive Phanerozoic stratigraphic record that reflects the geological evolution of the northern flanks of continental assemblages that include Laurentia, Eurasia, and Pangea. Svalbard’s Phanerozoic sedimentary and paleoclimatic archive is controlled largely by Svalbard’s overall northward plate-tectonic motion from …

Genome-Wide Discovery Of Multiple Sclerosis Genetic Risk Variant Allelic Regulatory Activity, Marissa Granitto, Lois Parks, Molly S Shook, Carmy Forney, Xiaoting Chen, Lee E Edsall, Omer A Donmez, Sreeja Parameswaran, Kristen S Fisher, Aram Zabeti, Lucinda P Lawson, Matthew T Weirauch, Leah C Kottyan

Faculty, Staff and Students Publications

Multiple sclerosis is an immune-mediated demyelinating disease of the central nervous system with a complex etiology involving environmental and genetic factors. Numerous genetic risk loci for multiple sclerosis have been nominated through genome-wide association studies, with most associated variants residing in noncoding regions. However, further work is needed to understand how genetic variation contributes to disease-related alterations to gene expression. Here, we use Massively Parallel Reporter Assays to identify genetic risk variants with genotype-dependent enhancing or silencing activity within a set of 14,275 variants distributed among multiple sclerosis risk loci that have reached genome-wide or suggestive significance. We applied our …

Low Mutation Rate But High Male-Bias In The Germline Of A Short-Lived Opossum, Yadira Peña-García, Richard J Wang, Muthuswamy Raveendran, R Alan Harris, Paul B Samollow, Jeffrey Rogers, Matthew W Hahn

Faculty, Staff and Students Publications

Age and sex have been found to be important determinants of the mutation rate per generation in mammals, but the mechanisms underlying these factors are still unclear. One approach to distinguishing between alternative mechanisms is to study species that reproduce at very young ages, as competing hypotheses make different predictions about patterns of mutation in these organisms. Here, we study the germline mutation rate in the gray short-tailed opossum, Monodelphis domestica, a laboratory model species that becomes reproductively mature at less than 6 mo of age. Whole-genome sequencing of 22 trios reveals one of the lowest mutation rates per generation …

Discovery Of A Novel Small Molecule Degrader Of Wild Type And Mutant Estrogen Receptors Using Dna Encoded Libraries, Anil Kumar Devakrishnan, Chandrashekhar Madasu, Yong Wang, Ramkumar Modukuri, Kurt M Bohren, Kevin R Mackenzie, Damian W Young, Suzanne A W Fuqua, Martin M Matzuk, Murugesan Palaniappan

Faculty, Staff and Students Publications

Estrogen receptor α (ERα) variants with mutations in the ligand binding domain (LBD) are less sensitive than wild type to standard-of-care drugs that bind ERα directly. To identify novel small-molecule drugs that target ERα mutants, we screened our multibillion-compound DNA-encoded libraries against ERα LBD variants. CDD-1274, which was highly enriched with all three variants, blocked spontaneous coactivator peptide recruitment to mutant ERα LBDs and inhibited estradiol-driven proliferative markers in several ER-positive breast cancer cell lines, but not in ER-negative breast cancer cells. We demonstrated that CDD-1274 induced proteasomal degradation of ERα variants in breast cancer cell lines and caused Y537S …

Slc35g3 Is A Udp-N-Acetylglucosamine Transporter For Sperm Glycoprotein Formation And Underpins Male Fertility In Mice, Daisuke Mashiko, Shingo Tonai, Haruhiko Miyata, Martin M Matzuk, Masahito Ikawa

Faculty, Staff and Students Publications

Despite the recognized importance of glycans in biological phenomena, their complex roles in spermatogenesis and sperm function remain unclear. SLC35G3, a 10-transmembrane protein specifically found in early round spermatids, belongs to the sugar-nucleotide transporter family, indicating its involvement in glycan formation. In this study, we found that Slc35g3 knockout male mice were sterile due to impaired sperm functions in uterotubal junction passage, zona pellucida binding, and oocyte fusion. Mouse SLC35G3 has UDP-GlcNAc transporter activity, and its ablation caused abnormal processing of the sperm plasma membrane and acrosome membrane proteins. Reported human SLC35G3 mutations (F267L and T179HfsTer27) diminished the UDP-GlcNAc transporter …

Integrated Analysis Of The Safety Of Fecal Microbiota, Live-Jslm In Adults With Recurrent Clostridioides Difficile Infection From Five Prospective Clinical Trials: An Update, Christine Lee, Paul Feuerstadt, Thomas Louie, Lindy Bancke, Beth Guthmueller, Adam Harvey, Frederikke Hoeyer, Robert Orenstein, Erik R Dubberke, Sahil Khanna

2020-Current year OA Pubs

BACKGROUND: Fecal microbiota, live-jslm (RBL) is approved in the United States and Canada for prevention of recurrent

OBJECTIVES: Provide an updated integrated safety analysis, incorporating final safety data from Punch CD3-OLS.

DESIGN: Safety data were combined from five RBL trials: three phase II and two phase III trials.

METHODS: Adult participants had documented rCDI and completed SOC therapy before receiving one or two doses of RBL or placebo, rectally administered as one treatment course. Treatment-emergent adverse events (TEAEs) were recorded for ⩽6 months.

RESULTS: TEAEs were reported in 70.9% (845/1192) of RBL recipients; most TEAEs were mild to moderate and …

In Vitro Antiviral Activity Of Cat’S Claw (Uncaria Tomentosa) Bark Extract Against Human Influenza A Virus, Juliann N. Makau, Keith K. Talaam, Mike Odiwuor, Janet M. Majanja, Sophia Musenjeri, Ratika Rahmasari, Samoel A. Khamadi, Ken Watanabe

Pharmaceutical Sciences and Research

Influenza A viruses mutate very fast and this leads to the development of resistance to antivirals, hence the need to find new therapeutics. Due to their extensive traditional use, natural products are crucial resources for the discovery of drugs. Cat’s claw (Uncaria tomentosa), is a tropical vine known for various health benefits and in this study we evaluated its anti-influenza activity. Pulverized material of the stem bark was extracted using 80% ethanol, hot water, and 1% sodium bicarbonate. The extracts were dried and dissolved in dimethylsulfoxide before testing for cytotoxicity and antiviral activity using crystal violet assay. The …