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Sleep, Endocannabinoid Signaling, And Cortical Processing In Mouse Models Of Autism Spectrum Disorder, Bryan Rodriguez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sleep plays a crucial role in memory consolidation, neuronal plasticity, and cognitive function. Individuals with autism spectrum disorder (ASD) often experience sleep disturbances, which are positively correlated with symptom severity. However, on the surface, sleep architecture is remarkably normal under baseline conditions in many rodent models of ASD. The goals if this dissertation were to investigate whether regulation of sleep, biochemical signaling during sleep, and downstream consequences of sleep on behavior are altered in two mouse models of ASD. In Aim 1, we tested the hypothesis that sleep phenotypes emerge in ASD models under conditions of high sleep pressure. We …

Saferespirator: Comprehensive Database For N95 Filtering Facepiece Respirator Leak Detection Including Infrared, Rgb Videos, And Quantitative Fit Testing, Geoffrey Marchais, Mohamed Arbane, Barthelemy Topilko, Jean Brousseau, Clothilde Brochot, Yacine Yaddaden, Ali Bahloul, Xavier Maldague

Études primaires

The COVID-19 pandemic underscored the challenges of performing mandatory Quantitative Fit Tests (QNFT) for healthcare professionals and the limitations of self-administered fit checks. To address this, it is crucial to develop faster and more efficient methods for detecting, locating, and quantifying leaks in Filtering Facepiece Respirators (FFRs), providing wearers with immediate feedback on their safety. Infrared (IR) technology, which relies on temperature variation analysis around the face seal, has proven effective for locating leaks but has not yet achieved automated quantification. This paper introduces a validated protocol for creating a comprehensive database to advance automatic leak detection. The database includes …

Mechanical And Antimicrobial Properties Of Green And Photoactive Agtio2/Poly(3hydroxybutyrate) (Phb) Electrospun Membranes, Safa Ladhari, Nhu Nang Vu, Alireza Saidi, Amine Aymen Assadi, Phuong Nguyen-Tri

Études primaires

The rise of antibiotic-resistant microbes and concerns over non-biodegradable waste highlight the need for innovative materials with integrated functionalities that address these critical issues. In this study, we synthesized poly(3hydroxybutyrate) (PHB) electrospun nanofibers blended with gelatin (Ge) and loaded with photoactive AgTiO2 nanoparticles with improved mechanical and biological properties. Biological tests revealed excellent antibacterial activity of the prepared membrane, with efficiency exceeding 99% against Escherichia coli and 95% against Staphylococcus epidermidis after 90 and 60 min of exposure to low-power commercial LED lights, respectively. Filtration studies using a dead-end stainless-steel cell reveal that both bacteria are eliminated (>99% after …

Study Of The Relationship Between Interoceptive Sensibility And Distress Tolerance In Community And College Samples, William W. Moore, Ashley Howell

Modern Psychological Studies

Interoceptive sensibility involves the detection, integration, and interpretation of internal bodily signals, primarily from cardiovascular, pulmonary, or gastrointestinal systems. Dysfunction in interoceptive processing has been increasingly recognized as a clinically relevant factor in numerous neurological, psychiatric, and behavioral disorders. This study aimed to elucidate the relationship between interoceptive sensibility and distress tolerance, hypothesizing that individuals with heightened interoceptive sensibility may report poorer distress tolerance. This relationship could help identify patterns between interoceptive sensibility and tendencies toward maladaptive coping strategies or emotional dysregulation. To explore these relationships, two studies were conducted utilizing self-report measures of interoceptive sensibility and distress tolerance in …

Born To Be Kind: The Evolutionary Significance Of Prosocial Behaviors In Humans, Yijia Xu

Modern Psychological Studies

Humans prefer kind romantic partners. Worldwide surveys have identified kindness as the defining feature of an ideal long-term partner, often explained as a signal for evolutionary fitness, demonstrating the ability to provide resources and ensure survival. Instead, we propose an alternative explanation: human preference for prosociality stems from an innate desire to be treated well. To test this, we asked participants whether they preferred kindness directed towards them or kindness exhibited more generally. Results indicate that participants were significantly more attracted to people who were kind to them personally than to people who were broadly kind to others. Interestingly, participants …

Leveraging Deep Learning For The Automated Detection Of Hemophilic Arthropathy In Knee Radiographs, En-Wei Lin, Edzer Wu, Ming-Ching Shen, Shao-Li Han

Rehabilitation Practice and Science

Background/Purpose:

Hemophilic arthropathy (HA) is a progressive joint disease caused by recurrent hemarthroses in patients with hemophilia. Early radiographic identification of HA is critical for timely intervention and long-term joint preservation. This study aimed to develop and evaluate deep learning models for automated detection of HA in knee radiographs.

Methods:

A retrospective dataset of 849 knee radiographs (AP and lateral views) was used to train three convolutional neural networks: ResNet-34, DenseNet-121, and EfficientNet-B0. Model performance was assessed using standard classification metrics, including accuracy, precision, recall, F1-score, and AUC. Interpretability was evaluated using Grad-CAM heatmaps.

Results:

DenseNet-121 achieved balanced performance on …

Diabetes Potentiates The Emergence And Expansion Of Antibiotic Resistance, John C. Shook, Benjamin P. Darwitz, Kaleb J. Tyson, Amanda Z. Velez, Sophia K. Bridwell, Joshua B. Parsons, Sarah E. Rowe, Christopher Marshall, Brian P. Conlon, Lance R. Thurlow

Biological Sciences Faculty Research and Publications

Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. We examined how diabetes affects the emergence of antibiotic resistance in a Staphylococcus aureus SSTI. We determined that S. aureus evolves antibiotic resistance rapidly in diabetic mice, while resistance did not occur in nondiabetic mice over the course of infection. Diabetes-associated immune cell dysfunction plays a minor role in the emergence of resistance, while hyperglycemia plays a dominant role facilitating the expansion and takeover of resistant mutants in diabetic infections. Furthermore, vancomycin intermediate resistant isolates display a pronounced fitness defect in …

Giant Cane (Arundinaria Gigantea) And The Swainson’S Warbler (Limnothlypis Swainsonii): Implementing Innovative Monitoring Techniques For Species Of Conservation Concern, Gabriela Carroll

Graduate Theses/Dissertations

In the U.S., following colonization and agricultural expansion, giant cane (Arundinaria gigantea) has been reduced to approximately 2% of its original extent, potentially causing shifts in the abundance and distribution of over 70 associated animal species. Among those species is the Swainson’s Warbler (Limnothlypis swainsonii), which has been known to occupy canebrakes during the breeding season. Though there is little known about the historical range of the Swainson’s Warbler and its current population status, some have hypothesized that its population may have declined due to the reduction of its suitable breeding habitat. As this species is …

The Long-Term Psychological Effects Of Violent Crime On Victims: A Review Of Evidence And Supportive Interventions, Jayden E. Oleksyn-Lamb

Graduate Theses/Dissertations

This study utilizes anonymous survey data collected from 26 mental health professionals in various regions of Canada to understand which psychological disturbances are the most prevalent among victims of violent crime as well as which psychological interventions are most beneficial for treating violent crime victims. The data revealed that Post-Traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), anger, guilt, self-blame, and shame are each highly prevalent. Findings also revealed that certain therapeutic methods including Eye Movement Desensitization Reprocessing (EMDR), Supportive Counselling (SC), Progressive Relaxation (PR), Cognitive Reprocessing Therapy (CPT) and Cognitive Restructuring (CR) are associated with …

Tailwater Trout Population Dynamics, Connor Dylan Cunningham

Graduate Theses/Dissertations

Dams have been constructed throughout the world and provide several resources for humans (e.g., flood control, hydropower). These structures heavily alter the upstream and downstream environment. One consequence of these alterations is the creation of “tailwaters”, which can create cold-water habitat via hypolimnetic releases. In the southeast United States these tailwater environments are often managed for the recreational use of nonnative salmonids. The unnatural flow regimes of tailwaters affect the biotic and abiotic conditions and ultimately the dynamic rate functions (i.e., recruitment, growth, mortality) of the fish inhabiting them. As such, the goal of this research is to provide fisheries …

The Effect Of Hypochlorous Acid On Cultured Osteoblast And Escherichia Coli, Cristina Flaquer Fusté

Graduate Theses/Dissertations

Hypochlorous acid (HOCl), a naturally occurring compound in neutrophils, has been used as an antimicrobial in wound treatment. Osteoblasts, bone-forming cells, within the bone tissue play a large role in bone fracture healing. Orthopedic infections are challenging to treat and highly morbid, including surgical site infection of arthroplasty procedures or infection in the setting of compound fractures. HOCl is being considered as a surgical antiseptic to decrease infections in orthopedic surgical procedures. This study therefore seeks to determine the effects of HOCl on osteoblasts and E. coli. Cultured osteoblasts were incubated with varying concentrations of HOCl to examine osteoblast …

Characterization Of The Overexpression Of Reca Homologs Rad51 And Dmc1 In Tetrahymena Thermophila, Jianna M. Cox

Graduate Theses/Dissertations

RecA homologs, Dmc1 and Rad51, work to repair DNA double-strand breaks (DSBs) within the cell through the recombination of homologous sections of DNA. Dmc1 works to repair programmed DSBs through meiotic recombination, while Rad51 functions to repair both meiotic and non-meiotic DSBs, the latter repaired through the process of homologous recombination repair (HHR). Chemotherapeutics, exogenous agents, work to form DSBs in cancer cells, attempting to inhibit the cell’s growth. A hyper recombinant phenotype is often seen in cancer cells due to the overexpression of RAD51, leading to drug resistance, the persistence of cancers, and an overall poor patient outcome. …

Activity, Movement, And Reproductive Patterns Of The Northern Giant Musk Turtle (Staurotypus Triporcatus) In Belize, Larissa Sage Saarel

Graduate Theses/Dissertations

The Northern Giant Musk Turtle (Staurotypus triporcatus), a near-threatened species native to southern Mexico, Guatemala, Belize, and western Honduras, faces multiple environmental challenges, yet its activity patterns, movement patterns, and reproductive biology remain poorly understood. This thesis investigates both seasonal activity and reproductive cycles of female S. triporcatus in Belize. To assess diel and seasonal activity, I tracked 12 female turtles and collected data using activity loggers. I also collected movement data through radio-telemetry and acoustic tracking methods. Results indicated that the species is primarily nocturnal, with increased activity during the wet season, particularly during flooding events. Turtles …

Cyber Warfare And The Future Of Conflict, Victor A. Mercado

Graduate Theses/Dissertations

This thesis examines whether cyber warfare now poses a more immediate threat to U.S. national security than weapons of mass destruction (WMD). Cyber operations have become a dominant instrument of contemporary conflict, with malicious actors operating in a persistent “grey zone” that blurs traditional boundaries between war and peace. These operations target military and civilian entities, both directly and often as collateral damage due to the uncontrollable nature of cyber threats. WMDs, despite their catastrophic destructive potential, remain largely constrained by established deterrence frameworks.

The evolving nature of cyber warfare warrants comparison to WMD effects and impact, as cyber capabilities …

Responses Of Native And Invasive Aquatic Vegetation To Changes In Water Depth In An Ozark Spring-Fed Pond, Daphne Miles

Graduate Theses/Dissertations

Spring-fed aquatic ecosystems in the Ozark Highlands are characterized by stable water depths, clear water, and diverse aquatic vegetation (filamentous algae, submerged, floating, and emergent plants). Sudden changes in water depth can impact aquatic vegetation dynamics but the impacts of prolonged changes are poorly understood. I investigated seasonal and annual changes to aquatic vegetation abundance in a spring impoundment during and after a two-year period of low water depth that was caused by a broken outlet below an artificial dam. Water depth was significantly lower in 2020 and 2021 (low water years), compared to 2022 and 2023 (high water years). …

An Introduction To U.S. Groundwater Law: Domestic And Transboundary Considerations, Caleb Cook, Gabriel Eckstein

Faculty Scholarship

In light of the scientific and historical factors that have shaped the development of groundwater law and policy, this chapter seeks to provide a primarily descriptive account of its current state in the United States and to lay a foundation for future efforts to address gaps in the regime. Section 8B.02 considers the importance of groundwater in modern American society, with a particular focus on its uses and the threats these resources face. Section 8B.03 describes the U.S. framework for the domestic governance of groundwater resources. Section 8B.04 describes the mechanisms for transboundary governance of groundwater between the United States …

Investigating The Production Challenges Of The P100.1 Phage Endolysin, Jonah O. Frago

EWU Masters Thesis Collection

Acne vulgaris is one of the most common skin diseases globally. One key aspect of acne pathogenesis is the disturbance of healthy strain diversity of the skin bacterium Cutibacterium acnes. Many acne treatments are antimicrobial; however, these treatments are generally nonspecific and carry a variety of side effects in addition to contributing to rising antibiotic resistance. Lytic bacteriophages (or phages) are viruses that infect and kill bacteria. Their lytic lifestyle is facilitated by enzymes called endolysins. Phages have been studied as an alternative to traditional antimicrobials in acne treatment and have shown reduced C. acnes load in acne lesions and …

Osteoclastogenic Potential Of Cd68-Expressing Osteoclast Precursor Cells, Colton Quinn

EWU Masters Thesis Collection

Bone remodeling is a dynamic process maintained by the balance between osteoblast-mediated bone formation and osteoclast-driven resorption. When this balance is disrupted, pathological bone loss occurs, as seen in osteoporosis, rheumatoid arthritis, and cancer-induced bone disease (Teitelbaum, 2007; Korol & Baumeister, 2023; Ensrud & Crandall, 2017). Osteoclasts, derived from hematopoietic stem cells through a macrophage lineage, play a central role in bone resorption. However, the identity of all proteins of osteoclast precursors remains unclear. CD68, a lysosomal glycoprotein widely expressed in macrophages and monocyte-lineage cells (Holness & Simmons, 1993), has been proposed as a marker of osteoclast precursors. Some studies …

Advancing The Environmental Dna And Rna Toolkit For Aquatic Ecosystem Monitoring And Management, Xavier Pochon, Holly A. Bowers, Anastasija Zaiko, Susanna A. Wood

Faculty Research, Scholarly, and Creative Activity

The application of environmental DNA (eDNA) and RNA (eRNA) technologies to aquatic ecosystem monitoring and management has increased rapidly in the last decade. These methods are providing many new and exciting opportunities for enhanced biodiversity assessment, ecological health evaluation, and species detection. This special issue of PeerJ Life and Environment brings together 20 innovative studies that collectively advance the eDNA toolkit. Four key themes are covered: (i) Methodological advancements, (ii) Ecological health assessments and biomonitoring, (iii) Species detection, and (iv) Application and management. The studies cover a suite of topics including; optimizing sample collection, developing species-specific assays, evaluating bioindicator species, …

Layover Start Timing Predicts Layover Sleep Quantity And Timing On Long-Range And Ultra-Long-Range Trips, Michael J. Rempe, Ian Rasmussen, Kevin Gregory, Cheyenne Johnson, Matthew Hsin, Erin Flynn-Evans, Amanda Lamp, Cassie J. Hilditch

Faculty Research, Scholarly, and Creative Activity

Study Objectives: Airline transport pilot sleep during layover is an important factor for alertness on subsequent flights. Assessing pilots' sleep on layover is an important first step in helping them obtain the most recuperative sleep possible on layover. Here, we investigate the quantity and timing of sleep during layovers and determine predictors for layover sleep. Methods: Sleep was assessed in 256 pilots flying a total of 473 long-range (LR; flight time 12-16 hours) or ultra-long-range (ULR; flight time > 16 hours) trips. Sleep was assessed using actigraphy. We employed linear mixed-effects models with layover sleep characteristics as the outcomes. The predictor …

Label-Free Visualization And Segmentation Of Endothelial Cell Mitochondria Using Holotomographic Microscopy And U-Net, Raul Michael, Tallah Modirzadeh, Tahir Bachar Issa, Patrick Jurney

Faculty Research, Scholarly, and Creative Activity

Understanding the physiological processes underlying cardiovascular disease (CVD) requires examination of endothelial cell (EC) mitochondrial networks, because mitochondrial function and adenosine triphosphate production are crucial in EC metabolism, and consequently influence CVD progression. Although current biochemical assays and immunofluorescence microscopy can reveal how mitochondrial function influences cellular metabolism, they cannot achieve live observation and tracking changes in mitochondrial networks through fusion and fission events. Holotomographic microscopy (HTM) has emerged as a promising technique for real-time, label-free visualization of ECs and their organelles, such as mitochondria. This nondestructive, noninterfering live cell imaging method offers unprecedented opportunities to observe mitochondrial network dynamics. …

Rural Families' At-Home Stem Tinkering Stimulates Creativity, Self-Expression, And Social-Emotional Engagement, Kristie S. Gutierrez, Kylie J. Swanson, Margaret R. Blanchard

Teaching & Learning Faculty Publications

Introduction: Informal STEM learning experiences include visits to museums, zoos, and aquariums as well as experiments and other activities performed at home. Family involvement in these experiences has been linked to increased student interest and participation in STEM fields; yet, scant research has been conducted on at-home STEM.

Methods: This descriptive case study investigated the tinkering experiences of nine rural middle school students and their families who participated in a series of interactive, at-home activities. The overarching research question was, in what ways do families engage in at-home STEM interventions? Data analyses of at-home audio recordings were guided by the …

Motion Planning For A Flexible Modular Raft Robot, Chun-Yi She

Dartmouth College Master’s Theses

This thesis presents a hierarchical motion planning framework for SoftRafts, a modular and deformable aquatic robot capable of performing locomotion and manipulation tasks on water surfaces. SoftRafts consist of soft and rigid components that enable structural reconfiguration, offering adaptability in unstructured aquatic environments.

To address the complexity of planning in high-dimensional, deformable systems, the proposed method uses a bounding-shape abstraction, specifically, enclosing circles and rectangular bounding boxes to simplify motion planning. These enclosures abstract the robot's overall shape, reducing the high-dimensional planning problem into a lower-dimensional problem. A global planner uses a probabilistic roadmap (PRM) to compute a collision-free path …

Paleomagnetic Assessment Of The Appekunny And Greyson Fms., Lower Belt Supergroup, Montana, Usa., Olivia C. Moehl

Dartmouth College Master’s Theses

The Belt Supergroup of the northwestern United States is one of the most extensive Mesoproterozoic sedimentary successions in North America. Although certain stratigraphic units have been well studied, correlations across the entire outcrop region remain unresolved. This project uses magnetostratigraphy and lithostratigraphy to investigate a potential lateral equivalency between the 1.4 billion-year-old (Ga) Appekunny Formation (Fm.) in Glacier National Park, MT and the 1.4 Ga Greyson Fm. in the Helena Embayment, MT. Both formations consist predominantly of shallow-water mudstones and contain the only North American occurrences of Horodyskia moniliformis, one of the oldest known macrofossils. Paleomagnetic analyses were conducted on …

Aestheticizing And Engendering Disease: The Case Of Tuberculosis, Abigail Dollries

Dartmouth College Master’s Theses

This thesis examines how tuberculosis, known in the nineteenth century as “consumption,” was aestheticized in American cultural and medical discourse, particularly in industrial cities of the North between 1830 and 1850. It addresses the paradox at the heart of the disease’s representation: while tuberculosis was medically pathologized, it was simultaneously romanticized, especially when afflicting elite white women. The central problem explored is how this aestheticization of illness functioned to reinforce gender, class, and racial hierarchies by transforming suffering into a symbol of virtue, refinement, and social status. Using a cultural-historical methodology, this project analyzes a range of sources, including medical …

Deep Brain Stimulation For Childhood Treatment-Resistant Obsessive-Compulsive Disorder: Mental Health Clinician Views On Candidacy Factors, Ilona Cenolli, Tiffany A Campbell, Natalie Dorfman, Meghan Hurley, Jared N Smith, Kristin Kostick-Quenet, Eric A Storch, Jennifer Blumenthal-Barby, Gabriel Lázaro-Muñoz

Center for Medical Ethics and Health Policy Staff Publications

Introduction: Deep brain stimulation (DBS) is approved under a humanitarian device exemption to manage treatment-resistant obsessive-compulsive disorder (TR-OCD) in adults. It is possible that DBS may be trialed or used clinically off-label in children and adolescents with TR-OCD in the future. DBS is already used to manage treatment-resistant childhood dystonia. Evidence suggests it is a safe and effective intervention for certain types of dystonia. Important questions remain unanswered about the use of DBS in children and adolescents with TR-OCD, including whether mental health clinicians would refer pediatric patients for DBS, and who would be a good candidate for DBS.

Objectives: …

On Minimizing Risk And Harm In The Use Of Psychedelics, Jules Evans, Marc Aixalà, Brian T Anderson, William Brennan, Rebecka Bremler, Joost J Breeksema, Lisa Burback, Abigail E Calder, Robin L Carhart-Harris, Katherine Cheung, Neşe Devenot, Ingmar Gorman, Jakub Greń, Peter S Hendricks, Brian Holoyda, Edward Jacobs, Joy Krecké, Daniel J Kruger, David Luke, Tomislav Majić, Amy L Mcguire, Nicky J Mehtani, David S Mathai, Kristin Nash, Tehseen Noorani, Roman Palitsky, Oliver C Robinson, Otto Simonsson, Elin Stahre, Michiel Van Elk, David B Yaden

Center for Medical Ethics and Health Policy Staff Publications

Objective: This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net.

Methods: A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety.

Results: The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors of those harms, and the most effective way to treat those harms. They also call for better support for those experiencing post-psychedelic difficulties, including better online information, peer support groups, affordable therapy, and psychiatric consultation and medication. Finally, the authors call for better …

Investigative Genetic Genealogy Practices Warranting Policy Attention: Results Of A Modified Policy Delphi, Christi J Guerrini, Louiza Kalokairinou, Jill O Robinson, Whitney Bash Brooks, Stephanie M Fullerton, Sara Huston, Jacklyn Dahlquist, Diana Madden, Norah Crossnohere, Nicola Campoamor, John F P Bridges, Amy L Mcguire

Center for Medical Ethics and Health Policy Staff Publications

A technique known as investigative genetic genealogy (IGG) was first introduced to criminal investigations in 2018, and it has since been used by U.S. law enforcement to help identify hundreds of criminal perpetrators and unidentified human remains. As expertise in IGG grows, policymakers have shown interest in regulating it. To help inform these efforts and to promote coherence in IGG governance as it expands, we recruited experts representing a spectrum of IGG-relevant professions and perspectives to identify and prioritize IGG practices for policy attention and to develop policy options for addressing them. In two rounds of a modified policy Delphi, …

A Hybrid Cloud Data Lake Architecture Supporting The Integration Of Clinical And Genomics Data, Apollo Mcowiti, Heidi Dowst, Fei Zheng, Susan Hilsenbeck, Christopher Amos

Center for Medical Ethics and Health Policy Staff Publications

Objective: Cancer centers must quickly integrate clinical genomics data from different vendors for oncology operations and research. Clinical data warehouse architectures are costly to construct and brittle, and they are not readily amenable to the rapid changes in oncology research. We introduce a cost-effective hybrid cloud Data Lake architecture for storing clinical genomic data from different vendors, aiding both clinical and research workflows.

Methods: We created a Data Lake architecture based on the zone architecture, with four layers: ingestion, storage, transformation, and interaction. The layers are implemented with a hybrid cloud architecture. Rich metadata created from patient and genomic data …

When Families Bridge The Research-Clinical Divide: An Exploration Of Values Regarding Cascade Screening In Genomic Research, Katherine E Bonini, Lauren R Desrosiers-Battu, Ann Katherine M Foreman, Nuriye N Sahin-Hodoglugil, Mary A Majumder, Candice R Finnila, Stephanie A Kraft, Laura M Amendola, Eimear E Kenny, Stephanie M Fullerton, Sara L Ackerman, Benjamin S Wilfond, Amy L Mcguire, Hadley Stevens Smith

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Genetic results are important for both patients and their biological relatives. However, cascade screening (CS) uptake is low, especially when testing occurs through research programs and not clinical care. Ethical guidance is needed for CS implementation when individuals receive clinical genetic results through research.

Methods: We conducted focus groups with 3 groups of individuals in the Clinical Sequencing Evidence-Generating Research Consortium: clinicians, patient representatives, and scholars of the ethical, legal, and social implications of genomics. We used inductive thematic and comparative analyses to analyze data within and across the groups.

Results: All participants (n = 27) agreed that …