Digital Commons Network^™

Engineering Novel Biomimetic Models Of Equine Host-Microbe Interactions, Lynn M. Leedhanachoke

Theses and Dissertations--Veterinary Science

One major limitation to the study of equine disease is the lack of in vitro models that accurately reflect the dynamic physiology of the horse. Thus, there is a pressing need to develop in vitro systems that recapitulate diverse equine tissue and organ microenvironments. To overcome this deficiency, we developed multiple biomimetic equine organoid systems that can be employed for a variety of investigations aimed at resolving outstanding questions in infectious disease pathogenesis, therapeutic development and drug metabolism, host defense mechanisms, immune-modulated disease, and equine developmental biology. Our innovative platform incorporates novel equine intestinal enteroid and airway organoid models derived …

Researching Dementia Indicators Among Rural Populations, Justin S. Yount

Theses and Dissertations--Community & Leadership Development

The study explored potential dementia indicators and risk factors among older adults residing in rural areas who are actively engaged in farming operations. Data was collected in three components a questionnaire, an audiogram test, and a memory impairment screening. 104 people responded to the questionnaire, 133 participants took the audiogram test, and 94 participated in the memory impairment screening. The findings revealed that 80.9% of participants showed no sign of cognitive impairment while 19.1% showed signs of possible impairment. Participants reported moderate levels of physical and social activity, but common risk factors such as elevated BMI, diabetes, hearing loss, and …

Influence Of Agrochemical Mixtures On Nitrogen Transformations In Floating Treatment Wetlands, Matthew Russell

Theses and Dissertations--Biosystems and Agricultural Engineering

Controlling losses of nitrate-N from agricultural fields to ground and surface water environments is one of the most pressing water resources problems today. Increasing levels of nitrate-N pollution in surface and groundwater is a critical threat to human and environmental health across the globe. To mediate nitrate-N losses, natural and constructed wetlands have been increasingly used as nutrient mitigation technologies and strategies. The use of wetlands as a treatment approach for nitrogen in runoff is a common practice in agroecosystems, however, nitrate-N is not the sole constituent present in agricultural runoff, and other biologically active contaminants have the potential to …

Nanopesticide Fate And Transport In Agroecosystems: A Field Study, John C. Stickney

Theses and Dissertations--Biosystems and Agricultural Engineering

Nanopesticides are an emerging class of pesticides associated with engineered nanoparticles that provide agricultural and environmental benefits. However, nanopesticide fate, transport, and persistence remain poorly understood. As do their potential impacts on the health of agroecosystems and influence on nutrient release. Therefore, this project investigated the fate, transport, and persistence of two widely available nanopesticides, an insecticide, nano-imidacloprid, and a fungicide, nano-copper hydroxide. The fate and transport in runoff water and soils of these nanopesticides, as well as their impacts on nutrients retention, were assessed through a field plot study over 2 growing seasons. Runoff from rainfall events and soil …

Impacts Of Utilizing Reverse Osmosis Concentrate On Mashing, Fermentation, And Water Use In Bourbon Whiskey Production, Ryan C. Sarhan

Theses and Dissertations--Biosystems and Agricultural Engineering

This thesis addresses the feasibility of reusing reverse osmosis concentrate (ROC) in the bourbon whiskey fermentation processes. Initial work compared laboratory-scale mashing and fermentation methods, demonstrating that simultaneous saccharification and fermentation reliably reflects industrial-scale processes, with lower complexity and process time. Building upon this, laboratory and distillery-scale experiments demonstrated that reusing ROC in the mashing and fermentation steps does not negatively impact ethanol yields. ROC produced by systems with a water softener was found to significantly increase mash rheology, suggesting a need for potential process adjustments. Softened ROC also altered the production of flavor-influencing volatile congeners. Under worst case conditions, …

Development Of A Cultivation System For Producing Pure Mycelium Materials From Distillers' Spent Grains, Keya Rani Roy

Theses and Dissertations--Biosystems and Agricultural Engineering

Stillage is a byproduct of distilleries which is rich in organic matter, minerals, and acidic components. It is commonly used as animal feed and has high potential for use as an alternative substrate for microorganisms. Filamentous fungi are saprophytes that can utilize stillage solids to grow as threadlike mycelium. The structure and composition of the filamentous mycelium has shown promise to produce pure mycelium materials (PMM), which might have many potential applications, for instance as a leather-like material or alternative protein food ingredient. Basidiomycota fungi (including true mushrooms) species are presently used in industry to produce PMM due to the …

Power Struggle: The Disproportionate Burden State Surrogacy Requirements Impose Upon Women, Courtney Harper Turkington

William & Mary Journal of Race, Gender, and Social Justice

The use of gestational surrogacy as a means to grow a family is increasing each year as fertility rates decline and single individuals and same-sex couples seek to have children who are genetically related to them. The United States does not have a uniform law governing surrogacy, leaving states to enact their own. While twenty-four states in this country have passed legislation permitting surrogacy and twenty-four others allow surrogacy in practice, the vast majority of states impose laws or practices that unduly burden women. In particular, Louisiana has the most restrictive surrogacy regime in the country. The state’s gestational carrier …

"'Let's Not Go To Camelot, 'Tis Illegal'": History And Tradition In Discriminatory Charter School Policy Justifications: The Chivalry Edition, J.M. Long

William & Mary Journal of Race, Gender, and Social Justice

This Article will begin in Part I with an overview of charter schools in the United States and a brief history of charter school growth in the United States. Part II then turns to focus upon charter schools and their growth in the state of North Carolina, emphasizing their legal uniqueness in relation to the North Carolina Constitution.

Second, CDS’s [Charter Day School, Inc.] dress code included a restriction for girls only— girls were required to wear either a dress or skorts (a combination of shorts covered with a skirt). Girls were not permitted to wear pants or shorts. The …

For The Right To Repair Oneself: Cybernetic Imds And The Plight Of Manufacturer Abandonment, Kathy Bacuta

William & Mary Journal of Race, Gender, and Social Justice

One in four people in the United States are disabled, making them the country’s largest minority. Yet they are well-known as the forgotten minority because they are often overlooked by governments and international organizations, and are rarely included in diversity and equity discussions. This is clear in how little the United States fights for the rights of the disabled. The disability aid and big pharma industries have been accused of being parasitic, the public has been accused of being unaccommodating, and the state and federal government has been accused of being unhelpful towards supporting the lives of the disabled. However, …

Sex Life Post Childbirth And The Role Of The Partner Relationship: A Qualitative Study, Agata Kopacz

PCOM Psychology Dissertations

Sexual problems are common among postpartum women, and sexual functioning during the postpartum period is affected by biological, psychological, and social factors. There is limited research exploring women’s experiences within their romantic relationships and sex lives during the postpartum period. This qualitative study utilized the phenomenological approach to gain a better understanding of the experiences of postpartum women in their romantic relationships and their sexual functioning after childbirth. A total of eight eligible postpartum women were interviewed individually. Data from the interviews were analyzed utilizing the phenomenological data analysis approach and grouped into emerging themes. Four themes were extracted for …

Front Matter

Transactions: The Tennessee Journal of Business Law

No abstract provided.

Enhancing Patent Valuation: Strategies For Improved Monetization And Market Impact, Daniel Mendoza

Transactions: The Tennessee Journal of Business Law

No abstract provided.

Get Ready With Me For Court: Increasing Ftc Enforcement In Influencer Marketing, Rosalena Morrell

Student Works

No abstract provided.

Let’S Negotiate: Analyzing The Impact The Inflation Reduction Act’S Drug Price Negotiation Program May Have On The Pharmaceutical Industry, Kristen Liu

Student Works

No abstract provided.

Scythian Spoils: Cultural Property Law And Antiquities Looting During The War In Ukraine, Charles Buschmann

Student Works

No abstract provided.

Florida’S “Don’T Say Gay” And “Don’T Say They” Laws: A Constitutional Inquiry Into Free Speech And Education, Sally A. Bright

Student Works

No abstract provided.

Essential But Unvalued: Incarcerated Workers Deserve The Same Standards And Protections As Free Workers., Lisa Roe

Student Works

No abstract provided.

The Undertreatment Of Patients With Chronic Pain Due To The Opioid Crisis, Nicole Ng

Student Works

No abstract provided.

Damping Modulation Of Dampened Kapton Surfaces, Sebastian Esteban

Honors Undergraduate Theses

When droplets are vibrated or disturbed, they can exhibit a complex sloshing motion, an understudied behavior in drop physics. Droplet sloshing involves a complex combination of transverse and longitudinal motion that changes the droplet's effective weight on the surface the droplet is on. Our current understanding stems from preliminary work focusing on a cantilever beam of fixed thickness and variable viscosity of the liquid being sloshed. This investigation will focus on how variable cantilever thickness and constant viscosity for a liquid being sloshed affects the beam's deflection under consistent vibration. It will also investigate how the natural frequency of a …

Integrated Compliant Structure For A Hand Exoskeleton, Tristan R. Koopman

Honors Undergraduate Theses

This thesis presents the design and prototyping of a wearable hand exoskeleton that integrates a flexible structural framework to assist with hand movement while maintaining comfort and anatomical conformity. The goal was to create a device that supports tendon-driven actuation through a compliant structure, combining elements of rigidity and flexibility to match the natural geometry and motion of the human hand. Traditional hand exoskeletons often trade off motion for structure or vice versa. This project aims to bridge that gap with a hybrid compliant design that balances flexibility and support. The design process followed an iterative approach involving rapid prototyping …

Fabricating Silver-Ceria Polymer Nanocomposite Scaffolds For Biomedical Therapeutic Applications, Shreya S. Pawar

Honors Undergraduate Theses

Improper healing of bone fractures and limited regeneration of bone following bone tumor resection remain a prevalent complication worldwide. Long-term effects of this include joint instability, limited movement, and arthritis. Bone infections (osteomyelitis), reactive oxygen species (ROS) generation via excessive inflammation, and underlying conditions such as osteoporosis can contribute to suboptimal bone tissue regeneration. ROS accumulation stimulates osteoblast apoptosis, while promoting osteoclast differentiation. These processes inhibit mineralization and osteogenesis. Conventional therapeutics involve the utilization of drugs and bone grafts. However, these approaches pose limitations and can result in subsequent complications. Microbial infections, ROS accumulation, and excessive inflammations are factors that …

Novel Nanomaterial-Based Platforms For Bio-Electrochemical Sensing And Photocatalytic Treatment Of Contaminants Of Emerging Concern In Water, Jonghyun Baik

Graduate Thesis and Dissertation post-2024

This dissertation presents the development of novel nanomaterial-based platforms for bio-electrochemical sensing and photocatalytic treatment of contaminants of emerging concern (CECs) in water, including heavy metals, polycyclic aromatic hydrocarbons (PAHs), per- and polyfluoroalkyl substances (PFAS), and microcystin toxins. Conventional detection and remediation methods are often costly, time-consuming, and impractical for field use. To overcome these limitations, in this dissertation, five distinct platforms were designed, developed, and evaluated under various water conditions.

First, a microbial fuel cell (MFC)-based biosensor was developed for detecting heavy metals (Cu²⁺ and Hg²⁺) and PAHs (benzene and xylene). The system exhibited rapid, linear …

Utilization Of Assessment Results To Improve Identification Of Prenatal Substance Exposure, Whitney R. Mendenhall

Doctor of Psychology (PsyD)

Prenatal substance exposure (PSE) significantly increases the risk of behavioral, emotional, and neurological challenges in children (Eiden et al., 2023). Children with PSE present similarly to children with attention deficit hyperactivity disorder (ADHD) and are often diagnosed with ADHD due to shared symptomatology (Garrison-Desany et al., 2022). However, PSE has a greater association with long-term cognitive, emotional, social, and behavioral deficits (Eiden et al., 2023). While PSE and ADHD share similar symptomologies, treatment and outcomes vary substantially, where early identification and treatment is a critical protective factor against the development of other psychological conditions in children with PSE. PSE can …

Sport-Related Concussions In Division Iii Athletes: A 10-Year Prospective Analysis Of Trends And Incidence, Shaylyn R. Thorne

Doctor of Psychology (PsyD)

Sports-related concussions (SRCs) among college athletes remain a growing area of concern due to a myriad of potential short and long-term implications. Understanding concussion trends and incidence in collegiate sports is critical for guiding prevention and management strategies. This study examined concussion injuries among NCAA Division III collegiate athletes at a single institution over a 10-year period. Analyses focused on trends in concussion incidence across sports, genders, and changes associated with institutional and NCAA policy updates. Results indicated that concussion incidence varied across sports and time, with higher rates in contact sports such as football and soccer. Significant differences occurred …

Multi-Trait Convergent Evolution Correlated With Host Ecology Suggests Trait Syndromes In Parasitoid Wasps (Hymenoptera: Braconidae)., Christina L. Watkins

Graduate Thesis and Dissertation post-2024

Convergent evolution, the independent evolution of similar traits in different lineages under shared ecological pressures, provides information on patterns of adaptation and character evolution. In Braconidae (Hymenoptera), a diverse and abundant parasitoid wasp family, the assorted biological and ecological traits of their insect hosts have been frequently hypothesized to drive repeated morphological evolution. This study presented the first family-wide phylogenetically informed test of host-driven convergence in Braconidae, integrating morphological and ecological data across 74 genera representing 32 subfamilies on the most current and robust phylogeny. Analyses revealed multiple instances of correlated evolution between host traits and parasitoid morphology, suggesting trait …

An Ailment I Will Fight With: Differential Diagnosis And Methodology Evaluation Of Possible Treponemal Infection At Dayr Al-Barsha, Egypt, Lindsey D. Lefebvre

Graduate Thesis and Dissertation post-2024

Treponemal diseases, including bejel, yaws, pinta, and venereal syphilis, have long plagued human populations and continue to pose public health challenges today. Despite their persistent global presence, the origins, transmission pathways, and archaeological identification of these diseases—caused by various subspecies of Treponema pallidum—remain contested. This study explores the utility of standardized diagnostic criteria, as proposed by Baker et al. (2020), in assessing the presence of treponemal disease in highly fragmentary skeletal remains from the Roman-period necropolis at Dayr al Barsha, Egypt. Through the examination of 14 individuals, this research seeks to (1) identify indicators consistent with bejel (T.p. …

Investigating The Impacts Of Peer Support And Online Information Seeking In Chronic Pain Online Health Communities, Aaron Necaise

Graduate Thesis and Dissertation post-2024

Chronic pain is a highly prevalent medical condition that contributes to intense emotional distress and social isolation in patients. With the growth of social media, online health communities (OHCs) have become a popular resource for patients to learn about their pain and establish social connections with peers. Although there is some evidence suggesting that curated online resources can benefit patient well-being, social media interactions have the potential to propagate medical misinformation and negativity. This dissertation expands upon the Social Communication Model of Pain to examine how interactions within social media-based OHCs impact chronic pain and uncover practical insights into OHC …

Genomic Consequences Of Habitat Fragmentation In The Florida Scrub-Jay: Diversity, Adaptation, And Disease Susceptibility, Maryam Ghoojaei

Graduate Thesis and Dissertation post-2024

Habitat fragmentation is a severe threat to biodiversity by reducing population size, gene flow, and adaptive potential, especially in habitat specialists like the Florida Scrub-Jay (Aphelocoma coerulescens). This dissertation integrates whole-genome sequencing and immunogenetics to assess the genomic consequences of habitat fragmentation across three primary Florida Scrub-Jay strongholds: Archbold Biological Station, Ocala National Forest, and Florida’s East Coast. In Chapter 2, I focused on adaptive genetic diversity at the Major Histocompatibility Complex (MHC) class II genes. I characterized MHC allelic richness, evaluated signatures of selection, and examined associations with pathogen infections. Despite population declines, I found moderate MHC diversity, suggesting …

Contagion Chronicles: A Spatiotemporal Analysis Of Armed Conflict And Infectious Disease, Devyn Escalanti

Graduate Thesis and Dissertation post-2024

This dissertation examines the relationship between armed conflict and infectious disease transmission through a novel theoretical framework that integrates ecological disturbance and health systems resilience theories into epidemiological contexts. The framework conceptualizes diseases along a continuum from "pulse" to "press." Pulse diseases, like Ebola, are characterized by sudden onset, high mortality, and short-term outbreaks. Press diseases, like HIV, progress gradually with lower mortality and long-term persistence. Grounded in this pulse–press disease typology and ecological and health systems resilience, the theory suggests that the absorptive capacity, adaptive capacity, and resilience of community health workers in conflict areas can influence disease transmission, …

Structure-Property Relationship For Silver-Incorporated Cerium Oxide Nanoparticles, Shanza Nusrat

Graduate Thesis and Dissertation post-2024

Cerium oxide nanoparticles are known for their applications across several domains due to their biocompatibility, high oxygen storage capacity, redox behavior, and stability. However, their intrinsic electrical conductivity is relatively low, which can limit their performance in energy storage applications. Doping cerium oxide with transition metals has proved to enhance conductive properties and, hence, their performance in related applications. This research investigates the doping of cerium oxide with silver (Ag) and its correlation with the properties of the material. Silver-doped cerium oxide nanoparticles were synthesized by wet-chemical synthesis at room temperature by a facile procedure. Cerium oxide was doped with …