Digital Commons Network^™

Rebuilding Possible: Pilgrimage And Learned Helplessness, Christianna Soumakis

International Journal of Religious Tourism and Pilgrimage

Learned helplessness is a belief in one’s own powerlessness which may develop after repeated exposure to stressful situations ranging from domestic abuse to public education. It is associated with pessimism, passivity in the face of obstacles, and depression. Pilgrimage, conversely, is associated with agency — striking out on one’s own in search of physical, emotional, cognitive, and / or spiritual transformation. Combining psychological literature with my personal experience as a pilgrim, special education student, artist, art facilitator for people with special needs, and professor, I argue that walking pilgrimages such as the Camino de Santiago offer a comprehensive opportunity to …

Precision Data-Driven Modeling Of Cortical Dynamics Reveals Person-Specific Mechanisms Underpinning Brain Electrophysiology, Matthew F Singh, Todd S Braver, Michael Cole, Shinung Ching

2020-Current year OA Pubs

Task-free brain activity affords unique insight into the functional structure of brain network dynamics and has been used to identify neural markers of individual differences. In this work, we present an algorithmic optimization framework that directly inverts and parameterizes brain-wide dynamical-systems models involving hundreds of interacting neural populations, from single-subject M/EEG time-series recordings. This technique provides a powerful neurocomputational tool for interrogating mechanisms underlying individual brain dynamics ("precision brain models") and making quantitative predictions. We extensively validate the models' performance in forecasting future brain activity and predicting individual variability in key M/EEG metrics. Last, we demonstrate the power of our …

High Cellular Plasticity State Of Medulloblastoma Local Recurrence And Distant Dissemination, Hailong Liu, Jing Zhang, Ziwei Wang, Wei Wang, Dongming Han, Xuan Chen, Yu Su, Jiao Zhang, Craig Daniels, Olivier Saulnier, Zeyuan John Wang, Chunyu Gu, Fei Liu, Kaiwen Deng, Dongyang Wang, Zhaoyang Feng, Yahui Zhao, Yifei Jiang, Yu Gao, Zijia Liu, Mingxu Ma, Yanong Li, Zitong Zhao, Hongyu Yuan, Youliang Sun, Yanfeng Shi, Tao Yang, Wenxing Li, Xueling Qi, Zejun Duan, Junping Zhang, Mingshan Zhang, Chunjiang Yu, Wei Jin, Xinguang Yu, Yu Tian, Shuaicheng Li, Chunde Li, Michael D Taylor, Jiankang Li, Yong-Qiang Liu, Xiaoguang Qiu, Tao Jiang

Faculty, Staff and Students Publications

Medulloblastoma (MB), a heterogeneous pediatric brain tumor, poses challenges in the treatment of tumor recurrence and dissemination. To characterize cellular diversity and genetic features, we comprehensively analyzed single-cell/nucleus RNA sequencing (sc/snRNA-seq), single-nucleus assay for transposase-accessible chromatin sequencing (snATAC-seq), and spatial transcriptomics profiles and identified distinct cellular populations in SHH (sonic hedgehog) and Group_3 subgroups, with varying proportions in local recurrence or dissemination. Local recurrence showed higher cycling tumor cell enrichment, whereas disseminated lesions had a relatively notable presence of differentiated subsets. Chromosomal alteration evaluation revealed distinct genetic subclones during MB progression, such as chr7q gain and chr11 loss in Group_3 …

Traf2 And Ripk1 Redundantly Mediate Classical Nfκb Signaling By Tnfr1 And Cd95-Type Death Receptors, Jennifer Wagner, David Vredevoogd, Xin Yu, Dong Lu, Daniel S Peeper, Heike M Hermanns, Jin Wang, Harald Wajant, Daniela Siegmund

Faculty, Staff and Students Publications

This study suggests a modified model of TNFR1-induced complex I-mediated NFκB signaling. Evaluation of a panel of five tumor cell lines (HCT116-PIK3CAmut, SK-MEL-23, HeLa-RIPK3, HT29, D10) with TRAF2 knockout revealed in two cell lines (HT29, HeLa-RIPK3) a sensitizing effect for death receptor-induced necroptosis and in one cell line (D10) a mild sensitization for TNFR1-induced apoptosis. TRAF2 deficiency inhibited death receptor-induced classical NFκB-mediated production of IL-8 only in a subset of cell lines and only partly. TRAF5, furthermore, failed to improve DR-induced NFκB signaling in HCT116-PIK3CAmut and HCT116-PIK3CAmut-TRAF2KO cells. These findings argue for a non-obligatory role of TRAF2 in death receptor-induced …

Geographic Disparities Impacting Oral Vaccine Performance: Observations And Future Directions, Rachel M Burke, Sasirekha Ramani, Julia Lynch, Laura V Cooper, Haeun Cho, Ananda S Bandyopadhyay, Carl D Kirkwood, A Duncan Steele, Gagandeep Kang

Faculty, Staff and Students Publications

Oral vaccines have several advantages compared with parenteral administration: they can be relatively cheap to produce in high quantities, easier to administer, and induce intestinal mucosal immunity that can protect against infection. These characteristics have led to successful use of oral vaccines against rotavirus, polio, and cholera. Unfortunately, oral vaccines for all three diseases have demonstrated lower performance in the highest-burden settings where they are most needed. Rotavirus vaccines are estimated to have >85% effectiveness against hospitalization in children < 12 months in countries with low child mortality, but only ~65% effectiveness in countries with high child mortality. Similarly, oral polio vaccines have lower immunogenicity in developing country settings compared with high-resource settings. Data are more limited for oral cholera vaccines, but suggest lower titers among children compared with adults, and, for some vaccines, lower efficacy in endemic settings compared with non-endemic settings. These disparities are likely multifactorial, and available evidence suggests a role for maternal factors (e.g. transplacental antibodies, breastmilk), host factors (e.g. genetic polymorphisms-with the best evidence for rotavirus-or previous infection), and environmental factors (e.g. gut microbiome, co-infections). Overall, these data highlight the rather ambiguous and often contradictory nature of evidence on factors affecting oral vaccine response, cautioning against broad extrapolation of outcomes based on one population or one vaccine type. Meaningful impact on performance of oral vaccines will likely only be possible with a suite of interventions, given the complex and multifactorial nature of the problem, and the degree to which contributing factors are intertwined.

Yield And Fruit Quality Of Two Strawberry Cultivars (Fragaria X Ananassa Duch.) Under Three Types Of Hydroponic Systems, Shwan Mohammed Baper, Shabaq Mohammed Nafea Hawezy

Polytechnic Journal

The experiment was carried out in greenhouse at Directorate of Agriculture Researches/ Ankawa - Erbil Ministry of Agriculture and water resources / Kurdistan Regional Government – Iraq during 26-9-2021 to 1-4-2022 to the aim, which are yield and fruit quality of two strawberry cultivars (Sabrina and Camarosa) production and fruit characteristics under three systems Hydroponics (Vertical Nutrient Film (NFT), deep water culture (DWC) and horizontal Nutrient Film (NFT). The results showed significant differences among the treatments, As the Sabrina cultivar had a superiority over Camarosa in terms of the size of the fruits, the percentage of un-marketed fruits, ( TSS%) …

Heterophily-Informed Message Passing

Defensive Publications Series

Graph neural networks (GNNs) are known to be vulnerable to oversmoothing due to their implicit homophily assumption. We mitigate this problem with a novel scheme that regulates the aggregation of messages, modulating the type and extent of message passing locally thereby preserving both the low and high-frequency components of information. Our approach relies solely on learnt embeddings, obviating the need for auxiliary labels, thus extending the benefits of heterophily-aware embeddings to broader applications, e.g. generative modelling. Our experiments, conducted across various data sets and GNN architectures, demonstrate performance enhancements and reveal heterophily patterns across standard classification benchmarks. Furthermore, application to …

The Effectiveness Of Cognitive Behavioral Therapy (Cbt) And Medication For Treating Major Depressive Disorder In Adults 18-45 And Factors Contributing To Treatment Resistance: A Case Series., Shavon R. Romita, Lindsay Gietzen

Pacific Journal of Health

Cognitive behavioral therapy (CBT) and antidepressant medications are often used to treat major depressive disorder (MDD). After examining the existing research on the treatment of MDD, a study was conducted using a vignette methodology to determine if there is a decreased rate of symptoms for patients who are currently being treated for MDD by a mental health professional utilizing CBT and antidepressant interventions. The study explored the effectiveness of CBT in reducing depressive symptoms when antidepressants alone had limited efficacy. The target population included adult patients experiencing MDD, with some presenting additional challenges such as cultural barriers, difficult diagnoses, and …

Conservation Of The Ancient Boat From The Sea Of Galilee, Orna Cohen

'Atiqot

The Galilee or Kinneret Boat, also dubbed “Jesus’ Boat,” was found and excavated in 1986. The various degrees of deterioration of the wood, the wood species and the size of the vessel were factors that reflected on the choice of the conservation method. Iron elements, such as nails, were also treated, and biological and bacterial problems were addressed. This report describes the chemical process of the conservation treatment of the wood and iron nails; the overcoming of biological and bacterial problems; and additional technical aspects of the conservation process. The report also describes the stages of preparation of the boat …

The Utah Statesman, January 20, 2025, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Current Issues Of Taiwan's Marine Protected Areas Legal Regime, Adrian Nugraha

Hasanuddin Law Review

As an 'Ocean Nation,' it is essential for Taiwan to make efforts to conserve its aquatic zones through marine protected areas (MPAs). Marine protected areas have considered one of the most precise methods of maintaining sustainable ecosystems and restoring fish stocks. This article discusses the legal regime for marine protected areas currently applied and its institutional arrangements in Taiwan. This study emphasizes legal issues in Taiwan's marine conservation efforts. This paper analyzes eight primary legislation relating to marine protected areas in Taiwan. Furthermore, to acquire actual field data, this study conducted interviews with a semi-structured questionnaire in three prominent Taiwan …

Children Rights To "Zero Hunger" And The Execution Challenges During The Covid-19 Crisis, Nurul Hidayat Binti Ab Rahman, Redwan Bin Yasin

Hasanuddin Law Review

Zero hunger is the world's pledge under the Sustainable Development Goals 2030, which aims to end hunger, achieve food security and improve nutrition. Nevertheless, the mission had been seized as the world faced economic turndown due to the outbreak of the COVID-19 virus. The circumstances have brutally affected societies ideal living standards and raised social problems such as extreme poverty, famishment, malnutrition, and medical conditions, specifically among vulnerable children. The essential purpose of this writing is to elucidate the zero hunger goal as one of the central legal rights and identify challenges in executing it during the COVID-19 crisis. Data …

Conceptualization Of Region-Specific Comprehensive Ocean Management Regime For Maritime Economic Exploration, M Rezaul Karim Chowdhury, Saharuddin Abdul Hamid, Nurul Haqimin Mohd Salleh

Hasanuddin Law Review

The history of the global economy is closely tied to the control of international trade routes, with maritime dominance playing a central role—evident in the supremacy of the Phoenicians, Arabs, and later European colonial powers. In the post-Cold War unipolar era, the USA has leveraged globalization through its maritime military hegemony. The Indian Ocean, particularly the Bay of Bengal (BoB), represents a critical hub for global sea trade and economic connectivity, intersecting with the South China Sea. Ensuring regional peace and stability is essential for sustaining international maritime trade and blue economic growth. This research introduces a novel Comprehensive Ocean …

Genetic Context Modulates Aging And Degeneration In The Murine Retina., Olivia J Marola, Michael Maclean, Travis L Cossette, Cory A Diemler, Amanda A Hewes, Alaina M Reagan, Jonathan Nyandu Kanyinda, Daniel A Skelly, Gareth R Howell

Faculty Research 2025

BACKGROUND: Age is the principal risk factor for neurodegeneration in both the retina and brain. The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain. Genetic makeup strongly influences susceptibility to age-related retinal disease. However, studies investigating retinal aging have not sufficiently accounted for genetic diversity. Therefore, examining molecular aging in the retina across different genetic backgrounds will enhance our understanding of human-relevant aging and degeneration in both the retina and brain-potentially improving therapeutic approaches to these debilitating conditions.

METHODS: Transcriptomics and proteomics were employed to …

Fast 3d Printing Of Fine, Continuous, And Soft Fibers Via Embedded Solvent Exchange, Wonsik Eom, Mohammad Tanver Hossain, Vidush Parasramka, Jeongmin Kim, Ryan W. Y. Siu, Kate A. Sanders, Dakota Piorkowski, Andrew Lowe, Hyun Gi Koh, Michael F. L. De Volder, Douglas S. Fudge, Randy H. Ewoldt, Sameh H. Tawfick

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Nature uses fibrous structures for sensing and structural functions as observed in hairs, whiskers, stereocilia, spider silks, and hagfish slime thread skeins. Here, we demonstrate multi-nozzle printing of 3D hair arrays having freeform trajectories at a very high rate, with fiber diameters as fine as 1.5 µm, continuous lengths reaching tens of centimeters, and a wide range of materials with elastic moduli from 5 MPa to 3500 MPa. This is achieved via 3D printing by rapid solvent exchange in high yield stress micro granular gel, leading to radial solidification of the extruded polymer filament at a rate of 2.33 μm/s. …

Timber Harvesting Was The Most Important Factor Driving Changes In Vegetation Composition, As Compared To Climate And Fire Regime Shifts, In The Mixedwood Temperate Forests Of Temiscamingue Since Ad 1830, Daniela Robles, Yan Boulanger, Jesus Pascual, Victor Danneyrolles, Yves Bergeron, Igor Drobyshev

Aspen Bibliography

Context The vegetation composition of northeastern North American forests has significantly changed since pre-settlement times, with a marked reduction in conifer-dominated stands, taxonomic and functional diversity. These changes have been attributed to fire regime shifts, logging, and climate change.

Methods In this study, we disentangled the individual effects of these drivers on the forest composition in southwestern Quebec from 1830 to 2000 by conducting retrospective modelling using the LANDIS-II forest landscape model. The model was run based on pre-settlement forest composition and fire history reconstructions, historical timber harvest records, and climate reanalysis data. We compared counterfactual scenarios excluding individual factors …

The Association Of Interoception, Emotion, And Reasoning In Social Conflict And Moral Decision Making, Jackson Thomas Hassler

Master's Theses

No abstract provided.

Biodiversity And Cold Tolerance Of Dung Beetles In Cattle Pastures And Forested Habitats In Northeast Arkansas, Becca Lynn Lett

Student Theses and Dissertations

Dung beetles play vital ecological roles, including dung removal and pest reduction. They rely on environmental temperature for activity, and forest habitats typically provide more favorable temperatures. This study occurred in Northeast Arkansas and compared dung beetle diversity in forests and pastures, finding greater diversity in forests. In addition, this study looked at abundance in one pasture 15 years apart and found that abundance remained stable over 15 years, while overall diversity increased. Thermal limit assays on three Onthophagus species provided insights into temperature tolerances. These findings offer valuable information on dung beetle abundance and diversity in the region and …

A Sensitivity Analysis Of The Modeling Of Polycyclic Aromatic Hydrocarbon Emission In Galaxies, A. Maragkoudakis, C. Boersma, P. Temi, J. D. Bregman, L. J. Allamandola, Vincent J. Esposito, A. Ricca, E. Peeters

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

We have conducted a sensitivity analysis on the mid-infrared spectral decomposition of galaxies and the modeling of the polycyclic aromatic hydrocarbon (PAH) emission spectrum with the NASA Ames PAH Infrared Spectroscopic Database (PAHdb) to assess the variance on the average galaxy PAH population properties under a grid of different modeling parameters. We find that the short-low and short-low+long-low Spitzer-IRS decomposition with PAHFIT provides consistent modeling and recovery of the 5–15 μm PAH emission spectrum. For PAHdb modeling, application of a redshift to the calculated spectra to account for anharmonic effects introduces a 15%–20% variance on the derived parameters, while its …

Scaling Arctic Landscape And Permafrost Features Improves Active Layer Depth Modeling, Wouter Hantson, Daryl Yang, Shawn P. Serbin, Joshua B. Fisher, Daniel J. Hayes

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Tundra ecosystems in the Arctic store up to 40% of global below-ground organic carbon but are exposed to the fastest climate warming on Earth. However, accurately monitoring landscape changes in the Arctic is challenging due to the complex interactions among permafrost, micro-topography, climate, vegetation, and disturbance. This complexity results in high spatiotemporal variability in permafrost distribution and active layer depth (ALD). Moreover, these key tundra processes interact at different scales, and an observational mismatch can limit our understanding of intrinsic connections and dynamics between above and below-ground processes. Consequently, this could limit our ability to model and anticipate how ALD …

The Constitutionality Of Inheritance Rights For Extramarital Children: Assessing The Legal Response Under Balinese Customary Law, I Nyoman Sujana, Irma Rachmawati Maruf

Hasanuddin Law Review

This article analyzes the inheritance rights of extramarital children under the post-Constitutional Court decision of Balinese customary law. Any child born of unmarried parents or out of adultery is stigmatized as an extramarital child (walad al zina) for his entire life and forbidden from inheriting an estate from his biological father. This legal issue is chosen as the main subject of this study is because of the legal circumstance in which the Balinese community does not grant status to extramarital children in matters of inheritance from the Purusa line. Hindu-Balinese religious leaders such as Parisada and the …

Water Quality Contributions Of Selected Buffalo River Headwaters In Searcy County, Arkansas, 2019–2023, Patrick Michael Dyer

Student Theses and Dissertations

Regulated by the National Park Service since 1972, the Buffalo River faces nitrogen, phosphorous, sediment, and fecal coliform contamination. Research assessing tributary water quality began with collecting water samples weekly from November 2019 until January 2023 (n = 156) near Tyler Bend Campgrounds. Pairwise analysis measured minimal water quality change from upstream to downstream on four headwater creeks. Data revealed that Tomahawk Creek’s fecal coliform bacteria were elevated above background levels, frequently exceeding state standards. National Land Cover Dataset class data were extracted to index land use at different scales. Simple linear regression, stepwise multiple linear regression, and a random …

Eia In Strengthening Law Enforcement And Penalties: A Case Of Corruption In Natural Resource Sector, Mochamad Agung Sasongko, Kosuke Mizuno, Suyud Warno Utomo, Raldi Hendro Koestoer

Hasanuddin Law Review

Corruption in Indonesia's natural resource sector is a significant issue with far-reaching consequences for environmental sustainability. Despite the detrimental effects of corrupt practices on the environment, law enforcement penalties for corruption often fail to compensate for their environmental impact. The aim of the study is to explore how the use of Environmental Impact Assessments (EIAs) strengthens law enforcement efforts and increase penalties for corrupt practices in Indonesia's natural resource sector. The method used is to collect and analyze regulations, policies, and corruption study cases to examine the relationship between EIA and corruption penalties. The results showed that EIA can help …

A New Treaty For Fully Autonomous Weapons: A Need Or A Want?, Maskun Maskun, Rafika Nurul Hamdani Ramli

Hasanuddin Law Review

Autonomous Weapon System (AWS) is still discussed and is considered to the principle of International Humanitarian Law (IHL) particular the principle of distinction and proportionality. In line with moral and ethical issues, some experts and global citizens agree that AWS will likely to distract moral and ethical on a battlefield and are never able to replace human’s feeling. Human beings are responsible over AWS because there is no such a fully autonomous weapons exist. It is always a human commander behind the actions. To bridge the situation on discussion of AWS, a new treaty should be created in order to …

Evaluating Sympton Clusters In First-Time Ischemic Stroke Survivors Who Discharge From The Hospital To Home, Paula De La Pena

Dissertations

The purpose of this study was to examine symptoms and relationships between those symptoms in first-time ischemic stroke survivors who discharge home after their initial stroke. Current measurement of recovery after stroke places emphasis on the physical aspects of recovery when current literature suggests that other, more subtle symptoms may be equally contributory to recovery. This descriptive, exploratory research study was conducted via a secondary analysis of both structured and unstructured data in a study cohort of 115 first-time ischemic stroke survivors from a tertiary academic medical center in the Midwest. Unstructured clinical notes were analyzed for the presence of …

Harmonization Of State, Custom, And Islamic Law In Aceh: Perspective Of Legal Pluralism, Mursyid Djawas, Abidin Nurdin, Muslim Zainuddin, Idham Idham, Zahratul Idami

Hasanuddin Law Review

Indonesia recognizes several legal systems i.e., state law, customary law, Islamic law, and international law. Islamic sharia in Aceh is part of legal pluralism in Indonesia. This study aims to discuss the application of Islamic sharia from the perspective of legal pluralism. This normative legal study employed a legal pluralism theory analysis. Legal pluralism is a theory that views law not only as positive or written law made by the state but also as a recognition of the legal reality that exists in a pluralistic society. The study collected data by means of a literature review. Findings revealed that Islamic …

Predicting Customer Churn In B2b Consulting Services, Mediya Alfalasi

Theses

The aim of this research was to develop a machine learning model that can predict customer churn in the consulting industry. The goal was to help businesses identify customers who might leave, allowing them to take action before it happens. To achieve this, a dataset was created by combining different data sources to reflect real-world customer behaviors. After cleaning the data and addressing issues like missing values and data imbalance, four machine learning algorithms—XGBoost, Neural Network, Random Forest, Logistic Regression, and Support Vector Machines (SVM)—were used to build the prediction models. The findings showed that XGBoost performed the best, achieving …

Government Policy In The Natural Resource Management Of Local Community, Revency Vania Rugebregt, Abrar Saleng, Farida Patittingi

Hasanuddin Law Review

Natural resource management is an important thing that should be done by the community for survival. Consciously of many ways in the management of natural resources has resulted in environmental damage, coupled with government policies that give permission without good supervision to entrepreneurs or private individuals in natural resource management adds a long list of environmental damage. In the last three decades, governments tend to ignore the phenomenon of legal pluralism in the legal development policy, preparation of legal instruments, as well as the implementation of the law through political neglect of the fact legal pluralism. So the product of …

Sistem Hukum Dan Teori Hukum Chaos, Amir Syarifudin, Indah Febriani

Hasanuddin Law Review

Keteraturan alam semesta dan objek lainnya dapat dideskripsikan baik oleh kosmologi maupun fisika. Namun dari keteraturan objek itu terdapat segi atau aspek ketidakteraturan atau fraktal (patah) yang sulit dideskripsikan oleh matematika model Auklides dan Kalkulus. Benoit Medelbrot mencoba menjelaskan objek kacau tersebut dengan teori Fraktal yang pada dasarnya merupakan cabang dari matematika. Teori Fraktal tersebut mempengaruhi pandangan terhadap hukum yang mengilhami Charles Sampford yang kemudian mencetuskan teori hukum chaos. Inti teori hukum chaos ialah (1) hubungan sosial, termasuk hubungan hukum dibentuk berdasarkan hubungan kekuatan (power relation), (2) pihak-pihak yang membuat hubungan itu tidak memiliki memiliki kekuatan yang sama atau seimbang, …

Reconstruction Of Strengthening The Right To Sustainable Groundwater (Assessing Model Policy In Bandar Lampung City), Erina Pane

Hasanuddin Law Review

Implementation of sustainable development related to the management of groundwater resources in the area can be realized with the establishment of a policy which is inseparable from the values prevailing in the society. The formation of ground water resources management policies is not only technically partial, but must also be comprehensive-holistic. Groundwater management activities include the conservation and utilization of groundwater organized to realize the sustainability and continuity of availability of groundwater and its sustainable benefit. Water resources policy in the form of government intervention should be able to improve the efficient use of water resources in an optimal and …