Digital Commons Network^™

Can We Eliminate The Negative Consequences Of Circadian Desynchronization Caused By Night Shift Work By Using A Light Therapy Lamp To Simulate A Sunset?, Amega Nguyen, Madison Payne, Amaka Eziakonwa, Erich Stahmer, Alexis Salinas, Samuel Park, Julie A. Zacharias-Simpson, Deborah Bell-Pedersen

Annual Research Symposium

This poster aims to understand the relationship between desynchronosis of circadian rhythms and night-shift work and how light therapy can mitigate some of the issues of desynchronosis. This study seeks to develop therapies for disrupted circadian rhythms from night-ship works.

Circadian Rhythm And Its Impact On Balance And Physical Performance, Angel Oliver, Christian Mccormick, Eseosa Aigbe, Tanner Erwin, Ariela Khandadash, Benjamin Khavkin, Samuel Park, Jutta Ward, Deborah Bell-Pedersen

Annual Research Symposium

This study explores the relationship between circadian rhythms and human performance across three key domains: cardiovascular endurance, vestibular function, and strength. Through the review of data obtained through performance testing at two different time points along with 24-hour physiological tracking, this study attempts to find correlations between circadian function and physical performance.

Quantifying The Impact Of Circadian Rhythm On Cognitive Domains: An Objective Assessment, Christian Mccormick, Angel Oliver, Neha Doppalapudi, Austin Gibson, Micah Kwallek, Bardia Movafagh, Samuel Park, Jutta Ward, Deborah Bell-Pedersen

Annual Research Symposium

This poster presentation explores the relationship between an individuals circadian clock and its effects on cognitive performance and overall cognitive function. By assessing the rhythms of multiple physiological parameters, this study aims to draw a connection with cognitive function in order to provide potential avenues for individualized treatments for those with disorders affecting cognitive function.

Investigating The Impact Of Shift Work On Circadian Rhythms And Health In Healthcare Workers, Dominique Gillette, Grace Godfrey, Jacob Godfrey, Angela Nguyen, Hannah Gewaid, Carissa Salamatin, Sharon Sengphanith, Samuel Park, Colin Burton, Neha Doppalapudi, Daniel Oraee, Deborah Bell-Pedersen

Annual Research Symposium

This poster presentation aims to discuss how working the night shift contributes to health risks through the disruption of circadian rhythm in healthcare workers. We hope to gain insight on the relationship between these disturbances and the circadian clock in order to establish strategies that optimize healthy lifestyles for healthcare workers.

The Multifaceted Impact Of The Covid-19 Pandemic On Perceptions Of Overall Health, Krystal Robinson, Grace Godfrey, Jacob Godfrey, Carissa Salamatin, Renee Chang, Payson Broome, Dominique Gillette, Kevin Tarrio, Sherli Koshy-Chenthittayil, Karen Duus

Annual Research Symposium

The World Health Organization (WHO) defines health as a “state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.” Previous studies have indicated both mental health and overall physical health can decline due to heightened sedentary behavior. This project investigates these concepts further by analyzing individual’s perceptions of their overall physical and mental health during the pandemic using Qualtrics and R. Participants aged 18 and older (n > 200) provided pre- and post-quarantine data with subgroup comparisons by gender, ethnicity, socioeconomic status, age, residence, and coping mechanisms. Initial results revealed a significant decline in …

Using Variations In The Circadian Rhythm To Identify Optimal Vaccination Times In Healthy Adults Who Receive An Influenza Vaccine, Payson Broome, Karen Duus, Thrisha Reddy, Krystal Robinson, Jutta Ward, Michael Desouza, Samuel Park, Terry Ann Else, Deborah Bell-Pedersen

Annual Research Symposium

This proof-of-concept quasi-experiment investigated the relationship between circadian phase and immune response to the 2024-2025 influenza vaccine. This study will provide insight into the ideal physiological circadian phase to receive the influenza vaccine, better defining the relationship between circadian biology and immunity, and supporting a simple and cost-effective strategy to optimize influenza vaccine efficacy.

Sex-Based Differences In The Utility And Outcomes Of Left Ventricular Assist Devices, Mirvat Alasnag, Waleed Alhabeeb, Feras Khaliel

Journal of the Saudi Heart Association

The totality of evidence suggests that there remains a significant disparity in the use of left ventricular assist devices (LVADs) and heart transplantation (HT) in women. This disparity persists even after accounting for differences in baseline characteristics, comorbidities, and cardiovascular risk factors between men and women undergoing LVAD implantation as a bridge to HT. Generally, women are less likely to undergo HT, leading to a higher mortality rate in women on the HT waiting list. The differences in risk profiles and device-related complications may account for the sex-related disparities in the assignment of device therapies. These findings warrant an urgent …

Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xxxv. Parabuthus Starhai Sp. N. From Somalia (Puntland) (Buthidae), František Kovařík

Euscorpius

A new species Parabuthus starhai sp. n. from Somalia (Puntland) is described. Combination of two characters, pectine teeth number 56–59 in both sexes and pedipalp chela length/ width ratio 3.65 in male and 5.47 in female differ P. starhai sp. n. from all other species in the region. Included is also a map of distribution of Parabuthus species in the Horn of Africa.

Lonza Partners With Unh To Offer Life Sciences Scholarship And Mentorship Program, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Sidi Zin Archaeological Project: New Investigations Into The Acheulean And Middle Stone Age In Tunisia, Eslem Ben Arous, Nabiha Aouadi, Lotfi Belhouchet, Héla Mekki, Kaïs Trabelsi, Mosbah Mabrouki, El Mabrouk Essid, Noômène Fehri, Qingfeng Shao, Christophe Falguères, Vincent Lebreton, Patrick Roberts, Robert Patalano

Biological and Biomedical Sciences Department Faculty Journal Articles

The Sidi Zin Archaeological Project aims to bridge understanding of the Acheulean–Middle Stone Age transition in northern Tunisia, a relatively understudied region in the context of hominin evolution. The Sidi Zin locality will provide chronological, palaeoenvironmental, geomorphological and cultural insights into Acheulean and Middle Stone Age occupations in Tunisia.

Nonadhesive Membranes: Preparation And Characterization Of Modified Phbhx Membranes, Funda Alkan, Murat Demi̇rbi̇lek, Oktay Aydin, Berrak Gümüşkaya Öcal, Neli̇sa Laçi̇n Türkoğlu, Mustafa Türk, Mehmet Ali̇ Onur

Turkish Journal of Chemistry

After abdominal surgery, there is a possibility of adhesions between the abdominal organs and the abdominal wall. Theadhesions can lead to problems such as chronic pain, intestinal blockage, and infertility. To prevent adhesion, antiadhesion patchescan be used. In this study, poly hydroxybutyrate-co-hexanoate membranes were fabricated as antiadhesion patches and modified witheither fatty acids or polyethylene glycol. The homogeneity and protein absorption of the membranes were assessed. The effects onblood coagulation factors were determined and the adhesion-proliferation properties of human fibroblast cells on the membranes weredetermined. The results show that myristic acid slightly increases surface free energy (40.7 ± 4.2 mN/m), …

The Daily Gamecock: February 2025, University Of South Carolina, Office Of Student Media

2025

No abstract provided.

Techno-Economic Analysis For Floating Offshore Wind And Offshore Green Hydrogen, David Pegler, Deborah Greaves, Robert Rawlinson-Smith, Simone Michele, Daniel Conley, James Benhin

School of Engineering, Computing and Mathematics

This paper describes a techno-economic model for exploiting the Celtic Sea wind resource through direct productionof hydrogen offshore. The model conceives a modular approach with eight 510 MW floating windfarms,each with an electrolyser system and export compressor mounted on a jacket. The model ensures an uninterruptedhydrogen supply to an industrial cluster (16.4 te.H2/h) by incorporating salt cavern hydrogen storage.During periods of no power generation, baseload power is provided from hydrogen fuel cells. The base-casemodel with a Discount Rate of 6% returned an Levelised Cost of Hydrogen (LCoH) of £7.25 per kg of hydrogen in2023. The LCoH shows strong sensitivity to …

Mcsa Forum Minutes 02/17/2025, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.

Climate Change As A National Emergency: Exploring Executive Powers, Greg Giunta

LSU Journal of Energy Law and Resources

No abstract provided.

Change Detection Analysis Using Remote Sensing And Gis Approaches For Lake Manzala, Egypt, Mohamed Eraki, Rasha Abd El Ghany, Sameh El Kafrawy, Mostafa Rabah

Mansoura Engineering Journal

Manzala Lake, the largest natural freshwater body in Egypt, is situated in the northeastern part of the Nile Delta. It faces major environmental challenges, largely due to pollution from untreated industrial effluents, sewage, and agricultural runoff. As part of Egypt's national initiative to rehabilitate its lakes, a development project was launched in 2017 and concluded in June 2022. The project aimed to purify the lake by eliminating contaminants, clearing invasive vegetation, deepening the canals, the study focuses on assessing land cover changes using remote sensing and GIS, and offers some recommendations for sustainable lake use following the development efforts. The …

America Runs On Biodiesel: Implementation Of A New Federal Mandate For Increased Renewable Energy Fuel, Asia Jackson

LSU Journal of Energy Law and Resources

No abstract provided.

The Lived Experiences Of Police Officers’ Responses To Stranger And Familial Child Abductions, Kennedy Pierce

Walden Dissertations and Doctoral Studies

When the media covers stories of child abductions, a common misconception is who the abductor is. Despite what the news broadcasts, a child is more likely to be abducted by a family member or acquaintance than a stranger. This qualitative study was conducted to explore the lived experiences of police officers’ responses to stranger and familial abductions using a phenomenological approach to determine how schemas may shape police officers’ perceptions, specifically concerning responding to child abductions. Schema theory suggests schemas are formed based on an occurrence between an individual and their surrounding environment. Nine interviews were conducted of police officers …

Resilience, Joshua Liashenko

Sociology Faculty Articles and Research

Once a ubiquitous framework for assessing the capacity for recovery, perseverance, and success in the face of adversity, resilience has been met with growing critiques in its application. As a frequently used “pretty word” within health disparities research, resilience has come to signify how at-risk communities overcome hardship in ways this work argues overdetermine their labor, activist potential, and existence. This critique examines resilience through the lens of ethnographic research conducted among transgender and nonbinary healthcare providers who provide gender-affirming care within their communities. As a marginalized community experiencing transphobia and increasing structural barriers to life-affirming and life-saving healthcare, trans …

The Rider (2025-02-17), Rebeca Salinas

The Rider Archives

Vol. 10, No. 19

Next-Generation Sequencing-Based Msi Scoring Predicts Benefit In Mismatch Repair-Deficient Tumors Treated With Nivolumab: Follow-Up On Nci-Match Arm Z1d, Jonathan D Schoenfeld, Nilofer S Azad, Jacob Gross, Li Chen, Michael J Overman, Katrina Kao, Latifa Jackson, Donna Brunnquell, Xiangning Bu, Christina Coppola, Ping Guan, Jennifer Lee, David Sims, Rebecca Fuchs, Jason L Weirather, Kathleen L Pfaff, Lauren Gunasti, Srin Ranasinghe, Stanley R Hamilton, Victoria Wang, Peter J O'Dwyer, Catherine J Wu, Scott J Rodig, David R Patton, Lyndsay Harris

Faculty, Staff and Student Publications

Purpose: Mismatch repair-deficient (dMMR) tumors have demonstrated favorable responses to immune checkpoint inhibition targeting PD-1. However, more in-depth identification of predictors of response could further refine patient selection for immunotherapy treatment.

Patients and methods: We undertook integrated evaluation performed on samples collected from 28 of 42 patients enrolled on the NCI-Molecular Analysis for Therapy Choice arm Z1D trial that evaluated PD-1 inhibition treatment with nivolumab in patients with noncolorectal dMMR tumors. Genomic analyses were performed using next-generation sequencing (NGS), whole-exome sequencing, and RNA sequencing and supplemented by multiplex immunofluorescence performed on tissue samples.

Results: In this dMMR population, more extensive …

Triswinunetr Lobe Segmentation Model For Computing Dir-Free Ct-Ventilation, Gabriela Roque Oliveira Nomura, Aarom T. Luong, Ananya Prakash, Annabelle Alemand, Tanish Bhowmick, Alisa Ali, Jaimie Ren, Basil Rehani, Girish Nair, Richard Castillo, Yevgeniy Vinogradskiy, Edward Castillo

Department of Radiation Oncology Faculty Papers

Purpose: Functional radiotherapy avoids the delivery of high-radiation dosages to high-ventilated lung areas. Methods to determine CT-ventilation imaging (CTVI) typically rely on deformable image registration (DIR) to calculate volume changes within inhale/exhale CT image pairs. Since DIR is a non-trivial task that can bias CTVI, we hypothesize that lung volume changes needed to calculate CTVI can be computed from AI-driven lobe segmentations in inhale/exhale phases, without DIR. We utilize a novel lobe segmentation pipeline (TriSwinUNETR), and the resulting inhale/exhale lobe volumes are used to calculate CTVI. Methods: Our pipeline involves three SwinUNETR networks, each trained on 6,501 CT image pairs …

A Qualitative Exploration Of Urgent Care Clinic Providers’ Experiences With Patients With Mental Health Concerns, Teresa L. Hodges

Walden Dissertations and Doctoral Studies

With mental health concerns on the rise in the United States and around the world, there has been a call for non-traditional avenues for the treatment of patients with mental health needs. Existing research indicates that in the current post-pandemic era, urgent care clinic providers have begun playing a pivotal role in the treatment of patients with mental health concerns. However, there is a lack of research currently available on the lived experiences of urgent care clinic providers treating of patients with mental health concerns. The purpose of this phenomenological study was to explore the lived experiences of urgent care …

Recent Developments In Heterologous Expression Of Cellulases Using The Pichia Pastoris Expression System: A Comprehensive Literature Review, Nazish Muzaffar, Abdur Raziq, Muhammad Waseem Khan, Niaz Muhammad Khan, Bushra Shahid, Anbareen Gul, Hayat Ullah

Biological Engineering Student Research

Cellulosic biomass is considered an important and sustainable source of renewable energy, which needs a complex mixture of different enzymes for its degradation. After amylase, cellulases are the second most important enzymes, gain more importance due to their broad range of applications at the industrial level, and are considered more economical and environmentally friendly; researchers have focused more on the production of cellulase with its higher expression rate and low cost. Pichia pastoris, a methylotrophic yeast strain, has a more effective and well-established system for the production of heterologous proteins, particularly for industrial enzymes. Moreover, its readily achievable high-density …

A Hindered Phenol Containing Pvc/Cuo Nanocomposites; Study On The Mechanical And Thermooxidative Properties, Mohsen Hajibeygi, Alireza Ghasemi

Turkish Journal of Chemistry

The effect of synthesized 5-((4-hydroxy-3,5-di-tert-butylphenyl)diazenyl)isophthalic acid (HBA) containing a hinderedphenol derivative on the thermooxidation, hydrochloric acid release time, and mechanical strength of PVC/CuO nanocompositeswas studied. Moreover, 5-((4-hydroxy-2,5-dimethylphenyl)diazenyl)isophthalic acid (HMA) was synthesized for comparison ofcorresponding PVC nanocomposite properties. PVC nanocomposite thin films were prepared through in situ surface modificationof CuO nanoparticles with HBA and HMA, individually, in the PVC solution. The XRD and FE-SEM results clarified the desirabledispersion of CuO nanoparticles. The PVC sample with loading of 5 wt% from each HBA and CuO was found to be the most thermallystable, which was confirmed by thermogravimetric analysis in inert conditions. The …

The Magnetic Beads-Based Sandwich-Shaped Immune Complexes For Rapid And Sensitiveamperometric Detection Of Sox2 Protein, Göksu Özçeli̇kay Akyildiz, Mehmet Altay Ünal, Seçi̇l Gülden, Si̇bel Ayşil Özkan

Turkish Journal of Chemistry

Sex-Determining Region Y-box 2 (SOX2) is a transcription factor protein. SOX2 expression is related to lymph nodemetastasis and distant metastasis in colorectal carcinomas. SOX2 was determined with the first magnetic disposable immunoplatform.The designed sandwich-shaped immune complexes were formed by a capture antibody, SOX2 protein, and biotinylated secondaryantibodies (dAb/HRP). The sandwich-shaped immune complex was linked to carboxylic acid functionalized magnetic beads (HOOC-MBs). This magnetic bioconjugate was dropped on the surface of the screen-printed carbon electrode (SPCE). The amperometricmeasurement was performed at –0.20 V in the presence of hydroquinone (HQ) and H2O2 against a silver pseudo-reference electrode.The optimization parameters affecting the immunoassay …

Masking Of Iron And Other Interferences During The Spectrophotometric Analysis Of Aluminum From Soil Samples Using Alizarin Red S, Hafiz Zain Ul Aabidin, Muhammad Inam Ul Hassan, Tariq Yasin, Muhammad Zubair Rahim, Ahsan Amin Bhatti, Hamayun Imtiaz, Asif Raza

Turkish Journal of Chemistry

In whole-rock geochemical analysis, the quantification of aluminum in geological samples is performed using differentanalytical techniques including UV-Vis spectrophotometry. During the spectrophotometric analysis of aluminum utilizing AlizarinRed S, iron causes significant interference, leading to inaccurate measurements of the amount of aluminum in the sample. In caseswhere leached or processed samples contain titanium, interference is also observed. However, appropriate masking agents can removethese interferences. In this study, various masking agents including Tiron, oxalic acid, ascorbic acid, and thioglycolic acid were utilizedfor the masking of iron. Among these masking agents, ascorbic acid proved to be the best candidate for masking iron. A …

A New Water-Soluble Silicon Phthalocyanine That Catalyzes The Photodegradation Of Pollutant Dyes, Damla Nur Kaya, Behi̇ce Sebnem Sesalan

Turkish Journal of Chemistry

The removal of color arising from water-soluble dyes in wastewaters is necessary to counter the threat to health. Because of thedifficulty in elimination of these dyes by conventional methods, their photodegradation using photosensitizers such as phthalocyanines(Pcs) has been employed recently. When compared to peripherally substituted derivatives, silicon Pcs are reported to be morebiocompatible with low toxicity. Thus a new silicon Pc substituted with two quaternized dimethylamino phenoxy units (compound 1)and its quaternized derivative (compound 2) were synthesized to test its photocatalytic ability employing the dyes methylene blue (MB),eosin B (EB), erythrosine (ERB), sulforhodamine B (SRB), and brilliant blue FCF (BRB), …

Simultaneous Determination Of Sunset Yellow And Tartrazine In Real Samples On An N-Butylamine-Graphite/Polyaminophenol Composite Electrode, Mürşi̇de Ceren Afşar, Zekerya Dursun

Turkish Journal of Chemistry

A composite electrode was fabricated for simultaneous determination of sunset yellow (SY) and tartrazine (Tz) in foods andsyrup. It is based on n-butylamine intercalation into graphite and then dropped on a poly (4-aminophenol)/glassy carbon electrode(GCE). The electrode surface morphologies, chemistry, and electrical properties were identified by scanning electron microscopy(SEM), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (RS), and electrochemical impedance spectroscopy (EIS). Thenew composite electrode significantly increased the electrochemical response of SY and Tz relative to a bare GCE. The peak currentof SY and Tz increased linearly depending on their concentrations from 0.006 μmol L–1 to 1.0 μmol L–1 (r = …

The Role Of Urinary Microbiome Analysis In The Diagnostic Approach And Management Of Urinary Incontinence: A Systematic Review, Pouyan Shaker, Zohreh Roshani, Ehsan Timajchi, Zahra Sharifi, Sarah Nikzadfar Goli, Behrooz Broumand, Mohammad Ali Shafiee

Student Publications

Urinary incontinence (UI) is a significant global health issue that impacts mainly middle-aged women, severely affecting their quality of life. Emerging research highlights the urinary microbiome's complex role in the etiology and management of UI, with microbial dysbiosis potentially influencing symptom severity and treatment outcomes. This systematic review aimed to evaluate the current evidence on the urinary microbiome's role in diagnosing and managing UI, focusing on variations in microbial composition across UI subtypes. We identified 21 studies, mostly employing 16S rRNA sequencing to characterize urinary microbiota and their associations with various UI subtypes, including urgency urinary incontinence (UUI), overactive bladder …